Research and development technician jobs in Memphis, TN - 20 jobs

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description They must have protein purification experience including non-labeled proteins and They are NOT looking for candidates with molecular/PCR/gene cloning, etc. Summary Description: Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. Duties: o Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). o Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. o Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. o Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. o Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. o Train Production Technicians in upstream and downstream manufacturing processes. o Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. o Write and execute validation protocols for new and existing manufacturing processes. o Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications Required Qualifications: o Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. o Extensive knowledge and hands on experience of protein purification and characterization. o Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. o Hands on experience with in vitro cell culture and recombinant protein fermentation o Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. o Proven experience with process scale-up procedures. o Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). o Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. Requirements (Physical, Mental, Environmental Demands): o Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. o Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. o Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. o Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. o Must be able to lift up to 30lbs. multiple times daily. o Must be able to travel by air/car to other locations of MBI as needed. o May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Manisha Jathar 732 429 1850

Life Unlimited. At Smith+Nephew we design and manufacture technology that takes the limits off living. This position is responsible for working in a cross-functional team of scientists and engineers to deliver on milestones associated with the entire lifecycle of additive-manufactured (AM), orthopedic products (i.e., early-phase research, new product development and product support). The individual is expected to apply his or her knowledge and practical skills in the field of materials science and engineering and additive manufacturing to serve as a technical leader within project teams and manage large-scope projects. With a minimal level of guidance, the individual will develop and execute testing plans, evaluate testing risk, and ensure adherence to all appropriate standards and documentation requirements. The individual's decisions will be guided by the existing policies, procedures, and business plans. What will you be doing? Design and conduct AM research studies to support the business throughout the product lifecycle. Work with minimal guidance and within cross-functional teams to achieve milestones for research programs where key focus is additive manufacturing, materials research, and materials process development. Work in a cross-functional team and provide direction on materials testing (internal vs external) based on capacity and capability. Liaise with regulatory bodies for testing requirements. Comply with laboratory management system according to international (e.g., ISO 17025) and S&N standards. Write, present and review test reports, retrieval reports, research manuscripts, presentations, white papers, customer communication documents, and invention disclosures related to materials research, process development and AM. Liaise with the national as well as international regulatory bodies as needed. Use expertise to solve unique and complex problems with broad impact on the business using innovative solutions. Propose, initiate, co-ordinate and review appropriate internal or external studies that will satisfy internal and external testing requirements. Communicate test plans and results to senior management as needed. Interact with and present to internal or external experts, HCPs, etc. Maintain strong knowledge of the AM and Ortho industries, current technical developments, customer needs and business opportunities to match unmet needs with AM solutions. Prepare presentations and technical material needed for sales, marketing and medical education teams as needed. Comply with the laboratory management practices set-up by the management including S&N global health, safety and environment practices. Create work instructions for safe and effective use of equipment in the laboratory. Manage laboratory equipment maintenance and calibration with internal and external resources. Assist other members of the team to order laboratory consumables, assist in the management of budgets and write capital requests as needed. Perform administrative functions as necessary (objective setting, development plans, training, self-appraisal, etc.). Write technical reports and ensure maintenance of complete and accurate records for all controlled documentation. Other miscellaneous activities include attending meetings, submitting financial/travel requests, coordinating team activities, conducting tours and making presentations. What will you need to be successful? In-depth knowledge of metal additive-manufacturing methods like laser powder bed fusion, e-beam powder bed fusion and/or binder jetting In-depth knowledge of the relationship between materials processing, microstructure and properties Experience characterizing materials via various methods (e.g., mechanical testing, metallography, microscopy, etc.) Bachelor of Science, Master of Science or Ph.D. in Mechanical, Materials, or Biomedical Engineering, or another appropriate field. Must have good team and communication skills. Requires use of email, internet and Microsoft Office software. 0 - 4 years hands-on experience. While performing the duties of this job, the employee is regularly required to stand; use hands to finger, handle, or feel objects, tools, or controls; reach with hands and arms; and talk or hear. The employee frequently is required to walk. The employee is occasionally required to sit and stoop, kneel, crouch, or crawl. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision, distance vision, depth perception, and the ability to adjust focus. You Unlimited. We believe in creating the greatest good for society. Our strongest investments are in our people and the patients we serve. Inclusion and Belonging- Committed to Welcoming, Celebrating and Thriving on Inclusion and Belonging, Learn more about Employee Inclusion Groups on our website ( ******************************* Your Future: 401k Matching Program, 401k Plus Program, Discounted Stock Options, Tuition Reimbursement Work/Life Balance: Flexible Personal/Vacation Time Off, Paid Holidays, Flex Holidays, Paid Community Service Day Your Wellbeing: Medical, Dental, Vision, Health Savings Account (Employer Contribution of $500+ annually), Employee Assistance Program, Parental Leave, Fertility and Adoption Assistance Program Flexibility: Hybrid Work Model (For most professional roles) Training: Hands-On, Team-Customized, Mentorship Extra Perks: Discounts on fitness clubs, travel and more! #LI-HYBRID Smith+Nephew provides equal employment opportunities to applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability. Stay connected by joining our Talent Community. We're more than just a company - we're a community! Follow us on LinkedIn to see how we support and empower our employees and patients every day. Check us out on Glassdoor for a glimpse behind the scenes and a sneak peek into You. Unlimited., life, culture, and benefits at S+N. Explore our website and learn more about our mission, our team, and the opportunities we offer.

National Carwash Solutions has grown over the past 45 years to become North America's largest equipment, service, and cleaning solutions provider in the car wash industry. Our world-class brands are backed by the largest service network in the country with more than 300 dedicated service professionals and growing! Come join us for an extraordinary career in a high growth, team-oriented company! The Gig: The Chemical Technician plays a critical role in our engagement and customer longevity. It is responsible for ensuring maximum customer satisfaction, troubleshooting and resolving immediate issues, proactively addressing any potential issues and identifying areas of opportunity as it relates to the customer experience. The typical number of sites this role is responsible for is 50-75 sites per month. What You'll Do: Provide professional, expert solutions to all customers, to enable their business to be profitable and leave their customers satisfied with a clean, shiny, dry vehicle every time they use our products Site Preventative Care & troubleshooting: Titration of product as needed Volumemetrics for product as needed Minor chemical equipment/application repairs Customer Satisfaction: Responsible for site chemical conversions & installations, and keeping the customers informed of progress Monitor customer levels and responsible for Chemical Inventory & replenishment orders placed at sites under responsibility Maintain Wash Key Reporting - Service Report Conduct NCS Site Surveys using the template Support & execute on corporate accounts (CTC) per the protocols Provide on-site revenue program training Conduct Technical & Chemistry basic training with appropriate location personnel Maintain accurate and up-to-date computer files (SF, Portal, Google & CTM) of customers and their issues Analyze customer outputs, and make recommendations on technical updates or ways to increase efficiency and wash counts for the designated site. Customer Expansion: Identify areas of opportunity for our account, conduct an initial intake discussion and communicate to sales management This individual is expected to comply with all applicable OSHA, EPA, Local Regulatory Law, and company safety policies. Management retains the discretion to add or change the duties of this position at any time. Qualifications: Associate Degree in Business Administration or related field preferred; or equivalent practical experience. Car Wash experience is preferred but not required Basic mechanical knowledge & aptitude Ability to communicate internally and externally across all levels of the organization Good microsoft office skills and basic knowledge of a computer Demonstrated ability to provide the highest level of customer service and support. Ability to function with minimal supervision and work in a team environment. Must be a self-starter and be extremely motivated. Exemplary organizational skills and attention to detail Ability to support overnight travel up to 40% based on territory & customer needs Pay: $28 - $33 hr Grow your career supported by an energized and passionate team, professional development, training, flexibility and opportunities for advancement. We offer competitive wages and benefits including comprehensive health, dental and vision coverage, matching 401(k), paid time off and more. National Carwash Solutions is a proud equal opportunity employer. We are a drug free, EEO employer committed to a diverse workforce. We will consider all qualified candidates regardless of race, color, national origin, sex age, marital status, personal appearance, sexual orientation, gender identity, family responsibilities, disability, education, political affiliation or veteran status.

Job Description **Role: Microbiology QC Analyst ** Duration: 6 Months Contract** **Shift: **Tue-Sat 2pm-11pm / Sun-Thu 2pm-11pm The Quality Control Analyst for the QC Microbiology Department will be responsible for performing processing of routine environmental monitoring samples, product-release testing, and raw material testing. The position requires the utmost attention to detail, good organizational skills, computer proficiency, and a basic understanding of microbiology and laboratory instrumentation. In addition, effective communication skills and the ability to function in a fast-paced, highly technical environment with minimal supervision are essential for success. ESSENTIAL DUTIES AND RESPONSIBILITIES:QC QC analyst QUALIFICATIONS:QC

Market Range: 05 Hiring Range: $19.10/Hourly THIS IS A PART-TIME GRANT FUNDED POSITION FUNDED UNTIL XXX (20 HOURS PER WEEK) JOB SUMMARY/ESSENTIAL JOB FUNCTIONS: The Research Technician 2 plans, implements, analyzes data needed for our large database studies, primarily working with software and datasets such as TriNetX, SEER-Medicare and other clinical datasets. This position assist with IRB and other regulatory requirements for the study. EDUCATION: Bachelor's Degree. (TRANSCRIPT REQUIRED) EXPERIENCE: OR Combination of college course work and work experience to equal four (4) years. KNOWLEDGE, SKILLS, ABILITIES: CITI training. Skill with SAS or R-programming. HIPAA training. Coordinates and prepares laboratory meetings with the Principal Investigator. Performs weekly updates on data cleaning, analysis, and planning. Performs regulatory checks. Writes scientific papers, submissions, and attends poster presentations. Performs data cleaning and reviews and assesses statistical methodology and data analysis. Assist with IRB and regulatory approvals. Assists in grant writing, manuscript preparation, and future analysis. Performs other duties as assigned.

The Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results. The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. St. Jude Children's Research Hospital is seeking a talented and motivated Associate Scientist or Scientist to join the clinical assay development team in Molecular Pathology. This bench-focused role, ideal for early-career researchers, will contribute to the advancement of innovative assays for future clinical applications. Our current priorities include developing assays that leverage long-read sequencing platforms and emerging methylation detection technologies. Strongly Desired Qualifications and Skills: Strong background in genomics, molecular biology, or a related field. Hands-on experience with different next-generation sequencing platforms. Ability to work effectively in a collaborative, multidisciplinary environment. Excellent communication skills and attention to detail. Experience with long-read sequencing and methylation detection would be a plus. Clinical laboratory training and experience with CAP-compliant documentation would be a plus. Experience with automation platforms would be a plus. Key Responsibilities: Contribute to the development and optimization of novel molecular assays for clinical implementation. Conduct pre-validation and validation wet-lab experiments with minimal supervision. Ensure high standards of data accuracy and reliability. Collaborate with bioinformatics scientists and pathologists to ensure analysis and interpretation of complex genomic data. Author and maintain SOPs and validation documentation in compliance with CAP regulations. Train laboratory staff on newly developed assays. Present research findings at internal and external conferences. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Scientist Minimum Experience: Eight (8) years of relevant work experience is required Six (6) years of relevant work experience is required with a Master's degree Three (3) years of relevant work experience is required with a PhD Salary range: $86,320.00 - $154,960.00 Associate Scientist Minimum Experience: 7 + years of research experience is required 5 + years of research experience is required with a Master's degree 2 + years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel preferred Proven performance in earlier role/comparable role Salary range: $65,520.00 - $114,400.00 Position is primarily onsite in Memphis, TN. Schedule Monday-Friday 8 a.m. to 4:30 p.m. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Associate Scientist or Scientist - Molecular Pathology. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description Job Position: Senior Manufacturing Technician or Senior Manufacturing Process Scientist Location: Memphis, TN Duration: Fulltime Permanent Relocation: Relocation Package is Provided Our Client is looking for Senior Manufacturing Process Scientist- With protein purification etc. experience…..!!!!! Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. SUMMARY & RESPONSIBILITIES: • Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). • Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. • Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. • Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. • Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. • Train Production Technicians in upstream and downstream manufacturing processes. • Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. • Write and execute validation protocols for new and existing manufacturing processes. • Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications QUALIFICATIONS AND SKILLS NEEDED: • Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. • Extensive knowledge and hands on experience of protein purification and characterization. • Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. • Hands on experience with in vitro cell culture and recombinant protein fermentation • Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. • Proven experience with process scale-up procedures. • Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). • Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. • MUST BE US CITIZEN or GREEN CARD holder only. Requirements (Physical, Mental, Environmental Demands): • Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. • Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. • Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. • Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. • Must be able to lift up to 30lbs. multiple times daily. • Must be able to travel by air/car to other locations of MBI as needed. • May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Regards Pooja Mishra Clinical Recruiter Integrated Resources, Inc. IT Life Sciences Allied Healthcare CRO Certified MBE |GSA - Schedule 66 I GSA - Schedule 621I Tel: 732 429 1636 (W) 732-549-2030 x 214 | (F) 732-549-5549 Gold Seal JCAHO Certified ™ for Health Care Staffing “INC 5000's FASTEST GROWING, PRIVATELY HELD COMPANIES” (8th Year in a Row)

Job Description National Carwash Solutions has grown over the past 45 years to become North America's largest equipment, service, and cleaning solutions provider in the car wash industry. Our world-class brands are backed by the largest service network in the country with more than 300 dedicated service professionals and growing! Come join us for an extraordinary career in a high growth, team-oriented company! The Gig: The Chemical Technician plays a critical role in our engagement and customer longevity. It is responsible for ensuring maximum customer satisfaction, troubleshooting and resolving immediate issues, proactively addressing any potential issues and identifying areas of opportunity as it relates to the customer experience. The typical number of sites this role is responsible for is 50-75 sites per month. What You'll Do: Provide professional, expert solutions to all customers, to enable their business to be profitable and leave their customers satisfied with a clean, shiny, dry vehicle every time they use our products Site Preventative Care & troubleshooting: Titration of product as needed Volumemetrics for product as needed Minor chemical equipment/application repairs Customer Satisfaction: Responsible for site chemical conversions & installations, and keeping the customers informed of progress Monitor customer levels and responsible for Chemical Inventory & replenishment orders placed at sites under responsibility Maintain Wash Key Reporting - Service Report Conduct NCS Site Surveys using the template Support & execute on corporate accounts (CTC) per the protocols Provide on-site revenue program training Conduct Technical & Chemistry basic training with appropriate location personnel Maintain accurate and up-to-date computer files (SF, Portal, Google & CTM) of customers and their issues Analyze customer outputs, and make recommendations on technical updates or ways to increase efficiency and wash counts for the designated site. Customer Expansion: Identify areas of opportunity for our account, conduct an initial intake discussion and communicate to sales management This individual is expected to comply with all applicable OSHA, EPA, Local Regulatory Law, and company safety policies. Management retains the discretion to add or change the duties of this position at any time. Qualifications: Associate Degree in Business Administration or related field preferred; or equivalent practical experience. Car Wash experience is preferred but not required Basic mechanical knowledge & aptitude Ability to communicate internally and externally across all levels of the organization Good microsoft office skills and basic knowledge of a computer Demonstrated ability to provide the highest level of customer service and support. Ability to function with minimal supervision and work in a team environment. Must be a self-starter and be extremely motivated. Exemplary organizational skills and attention to detail Ability to support overnight travel up to 40% based on territory & customer needs Pay: $28 - $33 hr Grow your career supported by an energized and passionate team, professional development, training, flexibility and opportunities for advancement. We offer competitive wages and benefits including comprehensive health, dental and vision coverage, matching 401(k), paid time off and more. National Carwash Solutions is a proud equal opportunity employer. We are a drug free, EEO employer committed to a diverse workforce. We will consider all qualified candidates regardless of race, color, national origin, sex age, marital status, personal appearance, sexual orientation, gender identity, family responsibilities, disability, education, political affiliation or veteran status.

**Role: MicrobiologyQC Analyst ** Duration: 6Months Contract** **Shift:**Tue-Sat 2pm-11pm / Sun-Thu 2pm-11pm The Quality Control Analyst for the QC Microbiology Department will be responsible for performing processing of routine environmental monitoring samples, product-release testing, and raw material testing. The position requires the utmost attention to detail, good organizational skills, computer proficiency, and a basic understanding of microbiology and laboratory instrumentation. In addition, effective communication skills and the ability to function in a fast-paced, highly technical environment with minimal supervision are essential for success. ESSENTIAL DUTIES AND RESPONSIBILITIES:QC QC analyst QUALIFICATIONS:QC Salary info: $21 - $24.50 / hr

Market Range: 05 Hiring Salary: $19.10/Hourly FUNDED UNTIL 10/31/2027 JOB SUMMARY/ESSENTIAL JOB FUNCTIONS: Under the direction of the Principal Investigator, Research Technician 2 conducts experiments following the behaviors of mice. EDUCATION: Bachelor's Degree. (TRANSCRIPT REQUIRED) EXPERIENCE: OR a combination of college coursework and work experience to equal four (4) years. KNOWLEDGE, SKILLS, AND ABILITIES: Skill in database analysis. Knowledge of brain surgery, brain Ca2+ imaging in vivo, behavioral testing, brain histology, and computational/statistical analyses. Ability to work independently, self-motivated and detail oriented. Assists with mouse brain surgery, molecular/cellular biology, and Ca2+ imaging. Assists in behavioral testing. Performs data analysis with assistance. Assists with brain clearing and imaging. Orders and maintains lab materials and equipment. Maintains and handle mouse lines in the vivarium. Assists with genotyping for the mouse lines. Performs other related duties as assigned.

We are seeking a highly motivated and talented associate scientist to join our team and lead cutting-edge research investigating the therapeutic potential of intrinsically disordered regions. The project will leverage pooled lentiviral screening pipelines of peptide inhibitors to systematically perturb key molecular interactions. This is an exciting opportunity to apply innovative high-throughput screening technologies to reveal new regulatory mechanisms and therapeutic targets. The successful candidates will play a central role in developing and implementing advanced lentiviral-based screening platforms across diverse biological systems, working at the interface of molecular biology, genomics, and translational discovery. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Design, optimize, and execute pooled lentiviral screening workflows for large-scale peptide inhibitor characterization Collaborate closely with bioinformaticians and project investigators to ensure robust experimental design, data acquisition, and analysis. Support the development of innovative experimental strategies to expand and enhance existing screening capabilities. Contribute to collaborative research outputs, including publications and conference presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Demonstrated expertise in the design, production, and application of lentiviral vectors for genetic manipulation and screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Excellent organisational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Extensive expertise in the design, production, and application of lentiviral libraries for large-scale screening. Familiarity with large-scale data generation and interpretation in screening contexts. Proven expertise in the design and execution of assays to characterise protein-protein interactions. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The post-holder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterization of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localisation. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in a relevant scientific area Minimum Experience: 7 + years of research experience is required with a Bachelor's degree. 5 + years of research experience is required with a Master's degree. 2 + years of research experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist (Pooled Lentiviral Base Editing Screening). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Our client is a public and rapidly growing diagnostics company that is looking to expand their Quality team in Memphis TN. They are willing to assist with relocation. This position will have no direct reports. Overview: This position is responsible for carrying out T-SPOT assays and other processes during validation of procedures, QC of finished product and raw materials, and to support the Quality Manager in the running of the Quality Management System and general administration of documentation for the QMS. This will include the following: Responsibilities: Overall responsibilities: 1. Maintenance of reference material, including cell culture and stock validation 2. QC of raw materials, incoming goods and any product manufactured by Oxford Immunotec 3. QC of manufactured products and assembled kits 4. Validation of procedures, equipment and software 5. Planning and conducting of stability testing procedures 6. Performing other laboratory testing as required 7. Maintaining the equipment databases to ensure all equipment is calibrated, maintained and serviced as required 8. Assisting with the control of Quality Management system documentation 9. Assisting with the preparation of further documentation for the Quality Management system 10. Assisting with the monitoring of compliance with the QMS and with tracking systems associated with CLIA, CAP, State requirements, ISO 13485:2012, ISO 9001:2008 and ISO 17025:2005 and the QSR 11. Assist the Quality Manager to ensure the continuing effectiveness of the QMS 12. Assist during internal and external audits 13. Conduct laboratory spot check audits 14. Assist with the QA review of documentation including non-conformances, CAPAs and complaints 15. Perform miscellaneous duties as necessary and requested by the Quality Manager Specific deliverables for the role are: 1. Contributing towards the maintenance of the quality of the Company's products in fulfillment of the Company goals 2. Control and conduct of product stability testing to support expiry dates and shipping claims 3. Monitoring of product conformity through archive kit testing 4. Assisting with ensuring compliance in the manufacturing process and documentation 5. Ensure that areas of responsibility do not contribute to any major non-conformance during external audits for GMP, ISO 13485:2003, ISO 17025:2005 and ISO 9001:2008 6. Regular communication with QA/QC team members and other functional groups to provide QC and validation support for both Process and Design controls 7. Working to Oxford Immunotec's Company Values at all times. 8. Follows all company safety policies & other safety precautions within work area 9. Regular attendance and timeliness is essential Qualifications QUALIFICATIONS: • Bachelor's degree, or college education and equivalent experience • 5+ years Quality experience, preferably in laboratory or medical device environmen ***Must have cell culture experience*** • Good working knowledge of MS Office • Experienced in working to GLP and Quality Management principles • Strong attention to detail and Quality commitment • High standards of mathematics and writing ability • Conscientious, thrives in high pressure work, and demonstrates strong initiative PHYSICAL DEMANDS: The physical demands described within the Position Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Minimal travel required including international travel. Job requires employee to walk considerable distances in the facility during the course of his or her work. Additional InformationAll your information will be kept confidential according to EEO guidelines.

Job Description **Role: MicrobiologyQC Analyst ** Duration: 6Months Contract** **Shift:**Tue-Sat 2pm-11pm / Sun-Thu 2pm-11pm The Quality Control Analyst for the QC Microbiology Department will be responsible for performing processing of routine environmental monitoring samples, product-release testing, and raw material testing. The position requires the utmost attention to detail, good organizational skills, computer proficiency, and a basic understanding of microbiology and laboratory instrumentation. In addition, effective communication skills and the ability to function in a fast-paced, highly technical environment with minimal supervision are essential for success. ESSENTIAL DUTIES AND RESPONSIBILITIES:QC QC analyst QUALIFICATIONS:QC Salary info: $21 - $24.50 / hr

An Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. An Associate Scientist position is available for a highly motivated scientist with a background in Circuits or Systems Neuroscience to coordinate the application of in vivo methodologies to assess neural function and animal behavior with multiple labs in the Developmental Neurobiology (DNB) department. This position is well-suited for an individual interested in transitioning from a postdoctoral position to a more stable, long-term position. The successful candidate will work directly with DNB labs to establish standard and innovative approaches for monitoring animal behavior in a wide variety of assays (motor, stress, cognitive, etc). It's expected that qualified candidates would have direct experience with several of the following methodologies: optogenetics, fiber photometry, in vivo calcium imaging, and/or machine-learning-based behavioral assessment. Additionally, it will be important for candidates to have familiarity with basic coding practices to coordinate data collection across multiple platforms (e.g, coordinating calcium imaging or optogenetic delivery with behavioral tracking). Job Responsibilities: Perform behavior-related experiments in collaboration with DNB lab members for the establishment and advancement of current projects. Implement and optimize algorithms for analyzing behavior data. Build or implement existing scripts to temporally align data across multiple modalities. Coordinate efforts with DNB researchers and established vendors (Med Associates, Inscopix, TDT Systems) to troubleshoot and optimize behavior-related data collection. Contribute to publications and presentations of research findings Maintains regular and predictable attendance Work independently and collaboratively with DNB labs. Provide guidance and training to less-experienced team members and may also train others outside the lab in relevant techniques. Perform other duties as assigned to meet the goals and objectives of the department and the institution. Maintain regular and predictable attendance. Preferred Qualifications: PhD in neuroscience, biology, computational neuroscience, or related fields. Demonstrated hands-on experience with neural circuit-based approaches. Strong programming skills (Python preferred). Experience analyzing time-series data, preferably from neuroimaging or behavioral studies. Knowledge of statistical analysis. Excellent communication skills and ability to work in a collaborative environment. Minimum Education and/or Training: Bachelor's degree in a relevant scientific area Minimum Experience: 7+ years of research experience is required 5+ years of research experience is required with a Master's degree 2+ years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel is preferred Proven performance in earlier role/comparable role. Preference will be given to applicants who have a strong background in leveraging in vivo approaches to solve complex problems in behavioral neuroscience. The candidate will also benefit from an outstanding, highly collaborative work environment in which research labs have diverse interests in understanding the underlying mechanisms of neural circuit function related to neuromodulation, motor output, and psychiatric disease. The Department of Developmental Neurobiology houses specialized departmental shared resources, including an integrated support structure for in vivo and ex vivo neuroimaging, behavioral phenotyping, computational neuroscience, genetic engineering, and single-cell genomics. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist - Circuits/Systems/Behavioral Neuroscience. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Our client is a public and rapidly growing diagnostics company that is looking to expand their Quality team in Memphis TN. They are willing to assist with relocation. Relocation assistance is provided! Excellent benefits, competitive salary, and stock options. Job Description Under direct supervision, responsible for design, performance and interpretation of experiments in support of the company's product development. Responsibilities: Responsible for the design and conduct of experiments as defined by work streams in accordance with the company's Quality System and to regulatory standards Ensures that work is completed to agreed timelines, communicating delays or issues to supervisor in timely manner Prioritizes workload to insure key objectives are met on time May supervise the work of a junior member of staff Presents data at internal and external meetings Ensures that conclusions in written reports reflect the data presented and reports are of the highest quality When required, operate as a scientist in support of running Laboratories, ensuring that the Quality Management System, including ISO 9001:2008, ISO 13485:2003, CLIA and CAP, is adhered to at all times and in all aspects of the job Perform other duties in departments on an occasional basis to meet critical company objectives Follows all company safety policies & other safety precautions within work area Regular attendance and timeliness is essential Qualifications BS or MS Degree in life sciences, Higher preferred Experience with cell culture techniques imperative Hands-on experience with flow cytometry and PCR techniques Demonstrated understanding of the diagnostic and pharmaceutical industries Familiarity with Quality System concepts and requirements including GMP and ISO Working knowledge of ELISA and ELISPOT a distinct advantage Expert at analyzing data Must be proficient in MS Office Additional InformationAll your information will be kept confidential according to EEO guidelines.

The Protein Technologies Center (PTC) comprises a team of 13 scientists within the Department of Structural Biology, specializing in protein biochemistry, molecular biology, biophysics, and structural biology. This center engages in collaborative efforts with various researchers at St. Jude to deepen the understanding of the molecular underpinnings of biological specificity and complexity. We are currently seeking an experienced Biophysicist/Surface Plasmon Resonance (SPR) Scientist to characterize molecular interactions utilizing SPR and other methodologies to support structural biology and ligand discovery initiatives. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. This position is a hands-on laboratory role suitable for an individual who enjoys both the design and execution of assays, while closely collaborating with fellow scientists and investigators. The selected candidate will be responsible for the operation and maintenance of SPR instruments and must possess the capability to independently plan, optimize, and carry out experiments aimed at measuring kinetic and equilibrium binding constants. Additionally, the individual will explore, develop, and apply novel methods and technologies to advance the understanding of protein-ligand interactions, oligomerization, stoichiometry, and stability. Responsibilities: Independently design, execute, and analyze high- to medium-throughput biosensor-based molecular interaction assays utilizing SPR instruments. Oversee daily operations, maintenance, and scheduling for all biophysical instruments within the center. Engage in the preparation of manuscripts and the presentation of findings in various professional forums. Ideal Candidate: Proficient, hands-on experience with Biacore instruments (T200, S200, 8K, or 1K) and/or other systems such as Carterra LSA, Bruker, Nicoya, or Sartorius SF3 for analyzing diverse molecular interactions. A good understanding of macromolecular structure, protein-ligand interactions, and biophysical characteristics. A proven ability to manage multiple projects concurrently. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. PhD strongly preferred. Minimum Experience: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of SPR Scientist in Protein Technologies Center. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us - Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. This position is with my direct client Position Details: Client Direct Client Location Memphis, TN Job Title Laboratory Supervisor Duration Permanent Position Must have skill-set [] Job Summary Under general supervision, implements laboratory policies, procedures, and services in accordance with the Quality Management System and in compliance with applicable regulations. Ensures efficient and effective laboratory operations by directing the work of others. Responsibilities: • Schedules sufficient number of laboratory personnel (i.e. technologists, technicians) to complete laboratory tests • Ensure all required policies and operational procedures are followed • Lead and coordinate daily workflows to support operation • Coordinate metrics to achieve throughput goals • Maintain daily inventory levels • Ensure that all lab staff is current with training, competencies and continuing education • Manage performance including appraisals, improvement plans • Follow and enforce adherence to Quality Management System • Track assay plate inventory • Communicate with cross functional teams to achieve operational efficiencies • Review and revise department standard operating procedures • Continually assess processes and create action plans to make improvements • Ensures compliance with regulatory standards, laws and requirements of requisite agencies by employing appropriate systems/processes. • Lead individuals and work groups to continuously improve performance by creating an environment that ensures application of quality principles and techniques to achieve desired outcomes • Creates an environment which fosters excellence, sensitivity and leadership • Follows all company safety policies & other safety precautions within work area • Regular attendance and timeliness is essential • Complete special projects as assigned within designated timeframe Qualifications Qualifications: • Requires the knowledge of theories, principles, and concepts typically acquired through completion of a Bachelor's degree in Medical Technology including up to one year of practical training and six years of full time clinical laboratory experience • Must have current certification as a Medical Technologist • Must obtain an active TN license as a Laboratory Supervisor • Requires the analytical skills necessary to plan for, design or enhance highly complex systems and programs, resolve problems requiring a comprehensive and state of the art awareness of scientific field • Requires the ability to effectively manage the employees within assigned unit/department and to persuade and negotiate with peer level managers on issues and programs that impact assigned unit/department. Work requires effectively dealing with conflicting views or issues and mediating fair workable solutions • Ability to recruit, develop and retain a high performing team • Ability to work independently and demonstrate a high degree of personal & professional initiative • Problem solving ability - able to develop creative, practical solutions that meet business objectives • Strong project management skills ability to create, adapt and follow work plans • Ability to work in a global, multicultural collaborative team environment • Ability to create cross-functional teams driven by project / business needs; ability to lead teams and secure outcomes without direct line authority • Strong skills in organizational/time management; able to manage multiple competing priorities simultaneously • Excellent verbal and written communication skills PHYSICAL DEMANDS: • The physical demands described within the Position Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. • While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers Feel free to forward my email to your friends/colleagues who might be available Additional Information Thanks!!! Warm Regards, Amrit Singh Clinical Recruiter Integrated Resources, Inc IT REHAB CLINICAL NURSING Tel: (732) 429 1634 Fax: (732) 549 5549 http://www.irionline.com Inc. 5000 - 2007, 2008, 2009, 2010, 2011, 2012,2013 & 2014 (8th Year) Certified MBE I GSA - Schedule 66 I GSA - Schedule 621I I GSA - Schedule 70

We are seeking a highly motivated and talented scientist to join our team and lead cutting-edge research exploring the therapeutic potential of intrinsically disordered regions. This project will harness pooled lentiviral screening platforms for base/prime editing mutagenesis to systematically perturb key molecular interactions. It offers an exciting opportunity to apply innovative high-throughput technologies to uncover new regulatory mechanisms and identify novel therapeutic targets. The successful candidate will play a central role in developing and implementing advanced lentiviral-based screening pipelines across diverse biological systems, working at the interface of molecular biology, genomics, and translational discovery. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Design, optimize, and execute pooled lentiviral screening workflows for large-scale base/prime editing mutagenesis. Collaborate closely with bioinformaticians and project investigators to ensure robust experimental design, data acquisition, and analysis. Drive the development of innovative experimental strategies to expand and enhance existing screening capabilities. Contribute to collaborative research outputs, including publications and conference presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Demonstrated expertise in the design, production, and application of lentiviral vectors for genetic manipulation and screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Excellent organisational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Extensive experience in CRISPR-based genome engineering in mammalian cell systems. Demonstrated expertise in the design, production, and application of lentiviral libraries for large-scale screening. Experience with base or prime editing systems. Familiarity with large-scale data generation and interpretation in screening contexts. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The post-holder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterisation of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localisation. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist (Pooled Lentiviral Base Editing Screening). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Join Our Team! The Center of Excellence for Pediatric Immuno-Oncology (CEPIO) is seeking an experienced Scientist to manage the Center's immuno-oncology preclinical murine modeling core. CEPIO serves as the central hub to advance and coordinate cross-disciplinary studies in immuno-oncology across St. Jude basic and clinical Departments, Cores, and Centers. The successful candidate is expected to have significant prior experience in developing and standardizing preclinical murine models to support target discovery, validation, and functional testing, including the generation of new genetically engineered mouse models (GEMMs). The Scientist will play a central role in developing and managing faithful disease models in vivo (e.g., GEMMs, surgically induced murine models) to support immuno-oncology research and translational efforts. This position offers the opportunity to engage in high-impact research with translational potential, contributing directly to developing novel cancer immunotherapies. Maintaining an up-to-date knowledge of, and having a high level of enthusiasm for, new and emerging technologies in preclinical murine modelling for immuno-oncology and their potential applications will be important. This includes beta-testing new tools, customizing technologies to fit CEPIO's research needs, and developing in-house protocols for complex experiments. The ideal candidate will work with collaborators across CEPIO with the goals of establishing faithful models to enable and support immuno-oncology research and translational efforts. Responsibilities Coordinate multiple aspects of research projects and execute laboratory experiments utilizing appropriate laboratory techniques, tools, and methods. Provide inputs regarding research protocols and experiments, set up protocols, and assist in developing new laboratory techniques as required. Identify, process, organize, summarize, review, and report relevant experimental data. Draft sections of research manuscripts as directed. Support monitoring and stocking of supplies, and calibration, maintenance, troubleshooting, and purchase of equipment within area. Instruct other staff in basic laboratory techniques and procedures. Design, troubleshoot, and refine experimental approaches to answer critical research questions. Process, organize, and analyze complex datasets, providing detailed reports on findings. Provide technical support for ongoing projects, including maintaining datasets, lab documentation, and compliance with safety regulations. Engage in collaborative research projects with internal and external teams to advance research and translation in immuno-oncology. Maintain regular and predictable attendance, contributing to a positive and productive lab environment. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Prior experience in lab techniques is preferred. Experience in lab and scientific project coordination, maintenance, and other research support activities preferred. Prior experience with the generation of GEMMs in immunology and/or cancer biology is highly preferred. Professional Growth Opportunities CEPIO provides a vibrant research environment with access to advanced tools and resources, including state-of-the-art imaging platforms and cutting-edge molecular biology techniques. CEPIO fosters a culture of collaboration, offering opportunities for professional development and advancement. We invite motivated scientists passionate about preclinical murine models and immuno-oncology to apply and join us in pushing the boundaries of immuno-oncology and immunotherapy in the fight against pediatric cancers. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Preclinical Modeling Scientist - Center of Excellence for Pediatric Immuno-Oncology. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.