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Phosphoramidite Scientist - Process Research & Development
Veranova
Research and development technician job in Devens, MA
Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
The Scientist role within the Chemical Development group will focus on the synthesis, process development, and analytical strategy for protected phosphoramidite precursors used in therapeutic oligonucleotide API manufacturing. This position is key to building Veranova's commercial capability in producing high-quality oligonucleotide building blocks. The ideal candidate will have strong expertise in phosphoramidite chemistry, including impurity profiling and customer-specific requirements. This role will also collaborate closely with the Analytical Team to establish robust characterization and control strategies that ensure exceptional product quality.
Core Responsibilities:
Develop and optimize synthetic routes for protected Phosphoramidite subunits used in therapeutic oligonucleotide API synthesis.
Identify and mitigate side reactions commonly associated with Phosphoramidite chemistry.
Define and implement specifications aligned with customer expectations for commercial-grade oligonucleotide precursors.
Provide expert guidance to the Analytical Team on the selection and application of appropriate analytical methods for product and impurity characterization, based on prior experience and industry standards.
Collaborate with cross-functional teams including Analytical Development, Quality, and Manufacturing to ensure successful scale-up and tech transfer.
Prepare technical documentation including batch records, specifications, and development reports in accordance with SOPs and cGMP guidelines.
Present scientific findings and project updates to internal stakeholders and external customers.
Support the establishment of quality and regulatory standards for commercial production of oligonucleotide precursors.
Contribute to project planning, budgeting, and timeline management for precursor development programs.
Other duties as assigned .
Qualifications:
Required
BS in Organic Chemistry or equivalent with 3-5 years related experience in a pharmaceutical industry, or
MS in Organic Chemistry or equivalent with 0-2 years related experience in the pharmaceutical industry.
Ability to read, analyze, and interpret English-language chemical periodicals, scientific journals, and regulatory documents.
Experience with organic synthesis and process development
Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS.
Experience in establishing integrated plans with defined resources and tasks.
Ability to write clear and concise technical reports.
Good understanding of Microsoft Office and statistical software.
Demonstrate ability to exercise good judgment and make decisions quickly.
Good written and verbal communication skills.
Ability to work independently and in a team environment.
Salary Range : $110,000 - $120,000 annual base salary
Our Commitment:
Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
$110k-120k yearly 2d ago
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Research Associate
Aequor 3.2
Research and development technician job in Framingham, MA
Title:- Research Associate I
Duration: Contract until Feb 2027 (Possible extension)
Overview/Department Description
We are seeking a contract upstream Research Associate to join our Cell Culture Platform group in Cell Culture Development department (CCD-CCP). CCD-CCP is a global business unit responsible for the development of cell culture platforms including media and bioprocess technologies for both fed-batch and perfusion from early and late-stage biologics projects, as well as all upstream CMC development activities for early phase projects (up to Phase II).
The candidate will be self-motivated and strongly driven to succeed while demonstrating the ability to function well within a fast-paced and collaborative team-oriented environment. The candidate will also be inquisitive and innovative, exhibiting scientific curiosity and the ability to acquire new skills for fed-batch and perfusion based upstream cell culture processes.
This is an exciting opportunity to learn cutting-edge cell culture techniques and develop cell culture subject matter expertise. This role will have significant impacts on early pipeline projects, next generation cell culture process development and manufacturing strategies within the global *** network.
Main Duties & Responsibilities
• Require to be on site daily; Weekend work required occasionally.
• Plan and execute experiments to optimize upstream cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
• Perform upstream experiments and collaborate with other functional groups to speed Phase I pipeline projects
• Contribute to technical reports, experimental protocols, and technical summaries for presentation internally and externally
• Participate in the technology transfer of processes into manufacturing facilities
• Ensure safety and environmental compliance are maintained in the workplace
• Some weekend working may be required for this role
Basic Qualifications
• Bachelor or Master's degree in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
• Post-education experience ?=3 years
• Understanding of aseptic technique and principles of mammalian cell culture
• Detailed in lab operations and quick learner for new technologies
Preferred Qualifications
• Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors
• Knowledge of CMC
MINAKSHI SANGWAN
Recruiting Lead - US Recruitment
O ************
E ***************************
W **********************
$64k-100k yearly est. 2d ago
Research Associate - Injectable Formulation
JMD Technologies Inc.
Research and development technician job in Lexington, MA
Prepare injectable (parenteral) peptide and protein formulations to support in vivo and in vitro animal studies, including buffer, excipient, and surfactant selection
Execute preclinical formulation development activities to support early research and screening programs
Perform biophysical characterization and stability studies to assess formulation performance and robustness
Support animal dosing studies by preparing, documenting, and delivering study-ready formulations
Maintain accurate experimental records using ELN (Electronic Laboratory Notebook) and manage formulation requests/workflows
Operate, maintain, and troubleshoot formulation, biophysical, and analytical laboratory instruments
Analyze experimental data and contribute to scientific documentation and reporting
Collaborate closely with cross-functional research teams to resolve formulation challenges and meet project timelines
$59k-86k yearly est. 1d ago
R&D Reliability Engineer
Formlabs 4.3
Research and development technician job in Boston, MA
## R&D Reliability Engineer---To all recruitment agencies: Formlabs does not accept agency resumes. Please do not forward resumes to our jobs alias, Formlabs employees or any other company location. Formlabs is not responsible for any fees related to unsolicited resumes. Unsolicited resumes received will be considered our property and will be processed accordingly.**Department:** Hardware Engineering **Location:** Boston, MA**What Formlabs Does:**At Formlabs, we're building the tools that make it possible for anyone to bring their ideas to life, from cutting-edge products to life-saving medical devices. Our 3D printing technology powers innovation at more than 50,000 industry leaders worldwide, including Apple, Google, Tesla, New Balance, and NASA. Together, we're helping creators design, prototype, and manufacture faster than ever before.We're a team of hands-on builders, engineers, and innovators reinventing how the world makes physical things. If you're ready to shape the future of fabrication, come build it with us.**Your Impact:**The Reliability Engineering Team is the company's independent voice on product robustness, ensuring our hardware products are reliable so that Customers spend more time printing and less time troubleshooting. We architect effective testing strategies, engineer advanced electro-mechanical test rigs, and extract valuable, actionable insights from the data.**R&D Reliability Engineering Team.****What You'll Do:*** Develop, execute, and manage system, subsystem, and component level validation test plans to ensure products meet design and reliability requirements.* Perform hands-on and data-driven root cause analysis (RCA) of electromechanical subsystems and field failures, utilizing common problem-solving methodologies and a "physics of failure" approach.* Design, build, and implement automated testing equipment for subsystem characterization and reliability/environmental testing.* Collaborate with R&D design teams throughout product development to perform risk assessments, manage continuous testing, and contribute to design reviews, influencing product design for reliability from day one.* Analyze field failure data to identify trends, prioritize investigations based on business value, and develop clear, actionable corrective action plans (CAPAs).**Our team did the testing to ensure Form 4 would be the most reliable printer Formlabs has ever built:*** **LCD & Light Engine:** Developed custom rigs to simulate UV light and heat, continuously monitoring performance over thousands of hours.* **Mixer Scraper:** Tested our proprietary debris detection hardware to protect the LPU from damage.* **Z-Axis:** Conducted millions of cycles of accelerated lifetime testing to ensure consistent motion.Tank Film: Developed custom pneumatic fixtures to ensure that tank tension remained high after tens of thousands of layers.* **Cartridge & Dispense System:** Optimized cartridge geometry to ensure reliable dispensing of all kinds of Formlabs materials.**to see a breakdown of these systems in action!****About You:*** Well-versed with complex electromechanical systems and passionate about understanding what it takes to make them work reliably.* Have experience with testing a wide range of sensors, actuators, and mechanical components.* Have experience developing system test plans and know how to execute them efficiently within fast-paced product development timelines.* Can prototype and run your own tests, from experimental setup to hardware and software implementation in Python.* Possess strong data analysis skills, capable of distilling complex test results and field data into clear, concise, and compelling insights that drive action.**Bonus Skills:*** Familiarity with Linux systems and scripting in various languages.* Experience with SQL for data analysis.* Prior experience with field failure analysis or quality engineering roles is a plus.**Our Benefits & Perks:*** Robust equity program to build future wealth through RSUs* Comprehensive healthcare coverage (Medical, Dental, Vision)* Low cost fund options in our 401K and access to advisors* Generous paid Parental Leave (up to 16 weeks)* Tenure-based paid Sabbatical Leave (up to 6 weeks)* Flexible Out of Office Plan - Take time when you need it* Ample on-site parking & pre-tax commuter benefits* Healthy on-site lunches, snacks, beverages, & treats* Regular sponsored professional development opportunities* Many opt-in culture events across our diverse community* And of course… unlimited 3D prints*We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.***Even if you don't check every box, but see yourself contributing, please apply.** Help us build an inclusive community that will change the face of 3D printing.**Compensation**We are all owners of Formlabs and direct beneficiaries of our success. We believe that equity is a critical component of compensation at Formlabs, and we want our newest team members to understand the potential value of their equity compensation. Full time employees receive equity, in the form of RSUs. Your financial investment will grow with us in accordance to your impact.At Formlabs, base pay is one part of our total compensation package and is determined within a range. Your base pay will depend on your skills, qualifications, experience, location and expected impact on the organization.The annual base pay range for this role is:$80,000-$125,000 USD
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$80k-125k yearly 5d ago
Downstream Scientist - Top Pharmaceutical Company
Insight Global
Research and development technician job in Andover, MA
We are looking for a Downstream Scientist to join our client's Manufacturing Sciences and Technology (MSAT) organization based in Andover, MA. The MSAT downstream purification team supports purification process development and optimization for commercial processes and next generation process development.
This person will be expected to execute and qualify various downstream purification unit operations, ensure the proper and timely execution of purification processing at both pilot and/or bench scale of various biologics using a variety of unit operations, such, depth filtration, TFF (UF/DF), and chromatography.
Experience with process development and characterization for a polysaccharide based programs and/or second-generation process development of biologics using various purification techniques.
Independently plan, design, and execute downstream experiments to enable technology transfer of polysaccharide programs and/or second-generation purification processes to receiving units.
Direct hands on experience with operation and maintenance of downstream equipment (AKTAs, Repligen TFF, etc.. and associated analytical tools (SoloVPE and Stunner etc..)
Proficient with data analysis, technical writing, reporting, and presenting to internal teams.
Support investigational studies and purification process troubleshooting as needed.
Drive a culture of safety, continuous improvement and operational excellence initiatives within department.
Independently plan, prepare, execute, and conclude critical material production campaigns.
Emphasize strong communication, teamwork, growth mindset and cross functional collaboration with other project teams as needed
EDUCATION AND EXPERIENCE
Bachelor's degree or higher in a relevant discipline with at least 3 years of applicable bioprocess experience.
Experience with process purification of biomolecules (mAbs, vaccines, etc…) from harvest to drug substance
Familiarly working in GxP cross matrix organizations
Lab-scale purification process development and troubleshooting experience with standard downstream equipment (e.g. AKTAs, Repligen TFF, etc…)
Direct hands on experience and knowledge of templated processes such as mAbs, pDNA, mRNA etc…
Proficient experience with data analysis tools such as Minitab, JMP, etc…
Working knowledge of PAT applications development and implementation from bench scale to pilot
Experience with HTS instrumentation for protein purification and process development
Working knowledge of GxP/ICH/Quality compliance systems of the biopharmaceutical industry
$70k-104k yearly est. 5d ago
Research Associate - Upstream Cell Culture
Spectraforce 4.5
Research and development technician job in Framingham, MA
Research Associate I
Assignment Duration: 12 Months
Work Arrangement: Onsite
Work Schedule
M-F 9 AM-5 PM EST (May require weekend work)
HM Notes:
Possibility of extension
• Local candidates ONLY
• References will be requested for finalists
• ***Weekend works is required and is occasionally. This is a rotating, schedule 1-4 hours on 1 weekend day and will include a Saturday or Sunday.
This will be included in 40 work week and no to exceed 40 hours.
Weekend work is pre-planned through end of year; new hire can swap with colleagues if available.
• Team of 13 members
• No chemicals
• No extreme heat or cold
• Cell culture media preparation
• Ability to lift 10 kg
• Free parking onsite
• Over 3 years of experience and PHD's considered overqualified
• No full gowning requirement
• PPE will be provided
Must Have Skills:
• Bachelor's or master's degree in chemical engineering Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
• Experience can include co-op or internships, 6+ months of experience.
• Understanding of aseptic technique and principles of mammalian cell culture
• Lab operations experience
• Understanding of aseptic technique and principles of mammalian cell culture
• Some lab mammalian cell culture experience, however, microbial experience is not a match
• MS Office, Word, Excel
• Quick learner for new techniques and technology
• Strong attention to details
Preferred Qualifications
• Up to 3 years of professional experience, or including internships
• Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors
• Knowledge of CMC
• Cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
• Strong GPA is a plus
Description:
We are seeking a contract upstream Research Associate to join our Cell Culture Platform group in Cell Culture Development department (CCD-CCP). CCD-CCP is a global business unit responsible for the development of cell culture platforms including media and bioprocess technologies for both fed-batch and perfusion from early and late-stage biologics projects, as well as all upstream CMC development activities for early phase projects (up to Phase II).
The candidate will be self-motivated and strongly driven to succeed while demonstrating the ability to function well within a fast-paced and collaborative team-oriented environment. The candidate will also be inquisitive and innovative, exhibiting scientific curiosity and the ability to acquire new skills for fed-batch and perfusion based upstream cell culture processes.
This is an exciting opportunity to learn cutting-edge cell culture techniques and develop cell culture subject matter expertise. This role will have significant impacts on early pipeline projects, next generation cell culture process development and manufacturing strategies within the global network.
Main Duties & Responsibilities
• Require to be on site daily; Weekend work required occasionally.
• Plan and execute experiments to optimize upstream cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
• Perform upstream experiments and collaborate with other functional groups to speed Phase I pipeline projects
• Contribute to technical reports, experimental protocols, and technical summaries for presentation internally and externally
• Participate in the technology transfer of processes into manufacturing facilities
• Ensure safety and environmental compliance are maintained in the workplace
• Some weekend working may be required for this role
Basic Qualifications
• Bachelor or Master's degree in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
• Post-education experience ?=3 years
• Understanding of aseptic technique and principles of mammalian cell culture
• Detailed in lab operations and quick learner for new technologies
Preferred Qualifications
• Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors
• Knowledge of CMC
$68k-96k yearly est. 3d ago
Research Associate I
Pyramid Consulting, Inc. 4.1
Research and development technician job in Framingham, MA
Immediate need for a talented Research Associate I. This is a 06+ Months Contract opportunity with long-term potential and is located in Framingham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.
Job ID:26-01448
Pay Range: $34 - $44/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).
Key Responsibilities:
Require to be on site daily; Weekend work required occasionally.
Plan and execute experiments to optimize upstream cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
Perform upstream experiments and collaborate with other functional groups to speed Phase I pipeline projects
Contribute to technical reports, experimental protocols, and technical summaries for presentation internally and externally
Participate in the technology transfer of processes into manufacturing facilities
Ensure safety and environmental compliance are maintained in the workplace
Some weekend working may be required for this role.
Key Requirements and Technology Experience:
Must have skills: - Understanding of aseptic technique and principles of mammalian cell culture, Cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
Bachelor or Master's degree in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
Post-education experience ?=3 years
Understanding of aseptic technique and principles of mammalian cell culture
Detailed in lab operations and quick learner for new technologies.
Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors
Knowledge of CMC
Note- Weekend works is required and is occasionally.
This is a rotating, schedule 1-4 hours on 1 weekend day and will include a Saturday or Sunday. This will be included in 40 work week and no to exceed 40 hours.
Weekend work is pre-planned through end of year; new hire can swap with colleagues if available.
Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.
Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.
$34-44 hourly 3d ago
Associate Scientist, Assay Development
Rangam 4.3
Research and development technician job in Cambridge, MA
Rangam is seeking candidates for a Direct Hire role as an Associate Scientist, Assay Development with our client, one of the world's largest pharmaceutical companies.
Seeking candidates in Cambridge, MA or willing to relocate.
Use Your Power for Purpose
Client's purpose is to deliver breakthroughs that change patients' lives. At the core of fulfilling this purpose is Research and Development, where we translate advanced science and technologies into the therapies and vaccines that matter the most. You will be at the forefront of this mission, contributing to the discovery and development of innovative treatments that improve patients' lives.
Client's BioMedicine Design (BMD) Assay Development group is seeking a highly motivated research associate to establish binding and functional assays and support hit-to-lead discovery of peptide and antibody-based therapeutics. The candidate will play a critical role in the design and execution of biochemical and of cell-based functional assays and high-throughput screening to support the BioMedicine Design portfolio. The candidate will be responsible for the development and execution of experiments using a variety of detection technologies including homogenous technology including HTRF, ELISA/DELFIA, FACS, imaging and cell-based functional assays focused on signaling, proliferation, or cytotoxicity. In addition, the candidate will analyze data, present results at internal meetings, and closely collaborate with project team members to develop strategies and identify lead molecules. We are looking for a creative, solution-oriented individual who enjoys the opportunity to explore new methods.
What You Will Achieve
In this role, you will:
Develop assays to identify and characterize peptide, antibody and multispecific candidates to support programs across multiple therapeutic areas. Biochemical assay formats may include protein binding, competition and enzymatic cleavage assays. Cell based assays may include binding (FACS and ELISA), competition, cell signaling (NanoBiT, calcium flux, cAMP, phospho-protein HTRF/AlphaLISA, etc) and reporter gene assays using a variety of cell lines.
Execute high-throughput screens using automated and semi-automated platforms and analyze results.
Collaborate with project teams to establish screening strategies, interpret results, and make decisions to drive programs forward.
Write protocols, maintain electronic lab notebook, and regularly review literature to maintain knowledge of scientific trends and new technologies.
Here Is What You Need (Minimum Requirements):
Bachelor's degree and 0-3 years of experience in molecular biology, biochemistry, cell biology or related discipline, along with a basic understanding of biologics drug discovery workflows.
Demonstrated experience in assay development and troubleshooting with methods such as HTRF, ELISA/DELFIA, FACS, and cell-based functional assays focused on signaling, proliferation, or cytotoxicity.
Demonstrated experience with plate-based assay formats and maintaining cell cultures is required.
Track record of strong problem solving and organizational skills, attention to detail, and ability to multi-task.
Strong written and oral communication skills
Bonus Points If You Have (Preferred Requirements):
Experience with Tecan or Beckman liquid handling platforms is preferred but not required.
Experience with high content imaging and multiplex assay formats is preferred.
Experience writing scripts to automate data processing or other coding experience is preferred.
PHYSICAL/MENTAL REQUIREMENTS
Requires work in BL2 laboratory environment with appropriate PPE
Work Location Assignment: On Premise
Last Day to Apply: January 22, 2026
The annual base salary for this position ranges from $60,200.00 to $97,500.00. In addition, this position is eligible for participation in client's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with client's Matching Contributions and an additional client's Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at client's Candidate Site - U.S. Benefits | (uscandidates.my**benefits.com). Compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
To find out more about Rangam, and this role, click the apply button.
Satnam Singh
SA Technical Recruiter | Rangam Consultants, Inc
M: **************
E: *****************| W: **************
$60.2k-97.5k yearly 2d ago
Associate Synthetic Chemist
Quadratic 3D, Inc.
Research and development technician job in Boston, MA
We are seeking an enthusiastic Associate Synthetic Chemist to support the discovery of small molecules for next-generation 3D printing resins. You will work hands-on in the lab, executing syntheses of novel molecules, characterizing products, and exploring photochemical and photophysical structure-property relationships. This role is ideal for highly motivated early-career chemists who love synthesis and are excited to accelerate innovation through fast, iterative chemistry. You will be closely mentored by experienced synthetic chemists and will collaborate with analytical scientists and engineers developing our printing systems.
Responsibilities
Design, execute, and troubleshoot small molecule synthetic routes, with a focus on divergent or modular approaches to rapidly generate lead candidates.
Purify products using chromatography and crystallization techniques.
Characterize compounds via UPLC, NMR, UV/Vis and IR spectroscopy, and mass spectrometry.
Work with cross-functional teammates to explore photochemical and photophysical structure-property relationships that drive 3D printing performance.
Maintain excellent electronic lab notebook documentation.
Contribute to management of chemical databases (e.g., commercial, proprietary, and virtual compound libraries).
Minimum Qualifications
Bachelor's degree in Chemistry or a closely related field with equivalent advanced chemistry coursework.
≥2 years of intensive organic synthesis laboratory experience (academic research and/or industrial roles).
Experience with synthetic planning with chemical databases (e.g., SciFinder, Reaxys).
Excellent command of synthetic and physical organic chemistry fundamentals.
Experience with air-sensitive techniques (e.g., Schlenk line), purification (chromatography/crystallization), and data interpretation (NMR / LC-MS).
Evidence of strong documentation and organizational skills, attention to detail, and the ability to manage multiple workflows efficiently.
Evidence of strong collaboration and teamwork talents/skills.
Ability to thrive in a fast-paced, collaborative R&D environment.
Preferred Qualifications
Command of the basics of photochemistry.
Experience with heterocyclic and/or extended aromatic systems, especially those relevant to organic (opto)electronics.
Benefits
We offer competitive compensation packages in our VC-backed startup.
Benefits include a full suite of offerings covering medical, dental, vision and 401k plan.
Beautiful setting looking out over a river and seaport; outdoor seating and picnic areas.
Highly collaborative work environment.
Additional Information
Travel: Occasional travel may be required from time to time
Location: Boston, Massachusetts
We value diversity in our company and are an Equal Opportunity Employer.
$62k-92k yearly est. 3d ago
Biomedical Informatics Associate - Research & Knowledge Graphs
Harvard University 4.2
Research and development technician job in Boston, MA
A prestigious research institution in Boston is seeking an Associate in Biomedical Informatics to support biomedical research training and projects. The role involves developing knowledge graphs, conducting data analyses, and writing research reports under the guidance of experienced mentors. Applicants should have a Bachelor's degree in computer science and a keen interest in healthcare technologies.
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$61k-87k yearly est. 4d ago
Analytical Scientist
Nextcea, Inc.
Research and development technician job in Woburn, MA
Nextcea Inc. is a pharmaceutical services company that focuses on assessing drug efficacy and safety during late-stage drug development and clinical trials. We are currently seeking full-time Analytical Chemists to join our team.
Qualified candidates will actively participate in LC-MS biomarker analysis at Nextcea. Successful applicants should hold an MS or PhD in Analytical Chemistry or a related field, along with relevant laboratory experience. While experience with LC-MS is preferred, it is not mandatory.
We are seeking self-motivated candidates who are excellent team players and can effectively contribute to established laboratory procedures and protocols. Candidates should be able to work independently, demonstrate flexibility, and adapt to the challenges of pharmaceutical biomarker projects.
At Nextcea, we value diversity and inclusion. We offer competitive compensation and benefits, including medical, vision, dental, and 401(k) plans, to all employees, regardless of their background or identity.
Applicants are required to submit their resumes online via LinkedIn.
$77k-109k yearly est. 3d ago
Senior Assay Development Scientist/Engineer
Siphox Health
Research and development technician job in Burlington, MA
+++
SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker.
We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing.
+++ The Opportunity +++
We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today.
This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels.
+++ What You'll Do +++
Core Assay DevelopmentDevelop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform.
Design, execute, and interpret experiments focused on:
Binding kinetics & equilibrium optimization
Surface functionalization strategies
Competitive assay dynamic-range shaping
Calibrator and control development (matrix selection, commutability)
Assay precision, stability, robustness
Analytical Performance & Validation
Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17).
Establish and demonstrate performance for:
Analytical sensitivity & functional limit (LoB/LoD/LoQ)
Linearity & reportable range (including hook effects, competitive assay inflection characterization)
Repeatability, reproducibility, and nested CV analysis
Interference and cross-reactivity studies
Matrix equivalency & recovery studies
Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks).
Cross-Functional Integration
Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance.
Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing.
Documentation & Execution
Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations.
Present results across the company to inform design decisions and product milestones.
+++ What We're Looking For +++
Technical Background
PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields.
Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus.
Demonstrated ability to independently solve complex analytical and biochemical problems.
Hands-on experience with complex analytical workflows, assay automation, and instrumentation.
Strong understanding of calibration design, commutability, and control strategies.
Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks.
Regulatory & Platform Experience (Bonus)
Experience with IVD development, ISO 13485, or 21 CFR 820.
Experience with POC or novel-platform assay development.
Knowledge of label-free sensors, waveguides, or photonic resonance systems.
Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation.
Personal Traits
Strong scientific intuition paired with rigorous data discipline.
Thrives in a fast-paced, milestone-driven startup environment.
Creative problem solver willing to challenge established assay paradigms.
High integrity, willingness to own outcomes, and a collaborative mindset.
+++ Why This Role Is Unique +++
Most assay developers spend their careers optimizing assays on platforms that already exist.
At SiPhox, you will:
Build the first generation of photonic immunoassays deployed in consumer health.
Design assays whose constraints are shaped by semiconductor physics as much as biochemistry.
Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins.
See your work ship in a product used at home by real people, not just research labs.
If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
$64k-94k yearly est. 3d ago
Senior Assay Development Scientist - Cancer Drug Discovery
The Institute of Cancer Research 4.4
Research and development technician job in Chelsea, MA
A leading cancer research institute is seeking a Higher Scientific Officer specializing in assay development and compound profiling. The successful candidate will apply screening science to advance cancer drug projects, developing plate-based assays to identify small-molecule inhibitors. This position offers a dynamic research environment supported by state-of-the-art facilities, a collaborative team, and competitive compensation. Ideal candidates will have laboratory experience and an understanding of enzymology, along with skills in automation equipment.
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$68k-98k yearly est. 1d ago
QC Analyst
Tandym Group
Research and development technician job in Woburn, MA
A recognized pharma company is actively seeking a new Quality Control (QC) Analyst for a great entry-level position with their QC Bioassay group. In this role, the QC Analyst will be trained to perform cell-based bioassays, ELISAs, and other biological methods in a GMP-regulated setting, while also supporting external laboratory testing.
Responsibilities:
Learn and perform immunoassays (e.g., ELISA) and cell-based assays under supervision in a GMP environment to support product release and stability testing
Assist in drafting and reviewing standard operating procedures (SOPs) and technical documents
Support method transfer, qualification of critical reagents, and other assay-related activities
Participate in the review and basic trending of QC data
Assist with routine laboratory upkeep, including cell culture maintenance, instrument calibration, and inventory tracking
Collaborate with internal teams and external partners as part of cross-functional project support
Contribute to investigations and deviation reports under guidance
Perform other duties, as needed
Qualifications:
Bachelor's Degree in Cell Biology, Molecular Biology, Biochemistry, or a related scientific field
Familiarity with basic Lab techniques and Data Analysis methods
Strong organizational, communication, and interpersonal skills
Detail-oriented and eager to develop problem-solving skills in a regulated lab environment
Enthusiasm for learning and the ability to work both independently and within a team
Desired Skills:
Academic or internship experience with Mammalian Cell Culture and/or ELISAs
$48k-78k yearly est. 5d ago
R&D Technologist
Gorton's 4.4
Research and development technician job in Gloucester, MA
Gorton's is seeking a passionate and technically skilled Associate Food Technologist to join our Innovation Team, supporting the development of next-generation frozen seafood products. This role will contribute to product ideation, formulation, and commercialization, with a focus on innovation while upholding our commitment to quality, sustainability, and consumer satisfaction.
What You'll Do:
- Support and potentially lead the creation of new frozen seafood products and improvements to existing products.
- Conduct bench-top formulation, prototype development, and plant trials.
- Develop and optimize cooking instructions and recipes for consumer use.
- Support multiple projects simultaneously and prioritize tasks for robust development plans.
- Maintain detailed records of formulations, testing protocols, and ingredient specifications.
- Ensure all products meet Gorton's quality standards, regulatory requirements (FDA, CFIA), and shelf-life expectations.
- Apply scientific principles and analytical thinking to solve problems and improve products.
- Demonstrate understanding of manufacturing systems, processes, and policies.
- Support production facility tests and process scale-up development.
- Contribute to ingredient optimization, cost savings, and sustainable sourcing initiatives.
- Continuously seek process and product improvements, challenging the status quo appropriately.
- Collaborate with cross-functional teams (marketing, operations, procurement, supply chain, finance, sales) to execute initiatives.
- Organize, facilitate, and lead product evaluation sessions, including cuttings and sensory panels, to assess internal prototypes and benchmark competitive products.
- Communicate project status, findings, and recommendations clearly to managers and cross-functional teams.
- Partner with Quality Assurance and Regulatory teams to ensure compliance with food safety standards.
- Conduct product presentations at sales and management meetings.
- Keep up with new technologies, ingredients, regulations, and industry trends.
- Leverage internal and external data to meet consumer needs and guide decisions.
- Support proper ingredients inventory of the lab for tests and experiments.
- Perform lab management tasks such as cleaning, sorting, and storing lab equipment.
What You'll Need:
- Bachelor's degree in Food Science, Chemistry, Microbiology, Biology, or related field with >2 years of relevant lab experience in food product development or manufacturing.
- Excellent oral and written communication abilities; able to translate technical concepts for diverse audiences.
- Ability to work independently and collaboratively with minimal supervision.
- Strong quantitative, analytical, and project management skills.
- Demonstrated ability to tackle new and unfamiliar tasks with minimal assistance.
- Basic culinary skills for creative recipe development and comfort in a product development kitchen.
- Good interpersonal skills and ability to work well on teams.
- Experience with experimental design and statistical analysis are a plus.
- Flexibility for early plant tests and willingness to travel (up to 30%).
- Proficiency in Microsoft Office, formulation software, and data analysis tools.
- Willingness to taste fish and shellfish prototypes and discriminate subtle flavor differences.
- Ability to lift up to 50 lbs.
Pay Range:
$60,632 - $71,240/Annual
$60.6k-71.2k yearly 60d+ ago
R&D Analytical Chemist
Dupont de Nemours Inc. 4.4
Research and development technician job in Marlborough, MA
Are you looking to power the next leap in the exciting world of advanced electronics? Do you want to help solve problems that drive success in the rapidly evolving technology and connectivity landscape? Then bring your problem-solving, passion, and creativity to help us power the next leap in electronics.
At Qnity, we're more than a global leader in materials and solutions for advanced electronics and high-tech industries - we're a tight-knit team that is motivated by new possibilities, and always up for a challenge. All our dedicated teams contribute to making cutting-edge technology possible. We value forward-thinking challengers, boundary-pushers, and diverse perspectives across all our departments, because we know we play a critical role in the world enabling faster progress for all. Learn how you can start or jumpstart your career with us.
We are seeking a hands-on, self-motivated Analytical Chemist to support New Product Development (NPD) and commercial product support across the ACP portfolio; ranging from metallization/plating chemistries to advanced packaging polymers and formulated materials. This role will lead development, implementation, and continuous improvement of analytical and characterization methods for specially synthesized raw materials (small molecules through complex polymers) and finished products, partnering closely with cross-functional stakeholders (DE, NPD, Manufacturing, Quality, and Technical Service) to enable scale-up, specifications, and customer support.
Key responsibilities
* Analytical method development & execution: Develop, optimize, and run analytical/characterization methods for raw materials, intermediates, and formulated products supporting NPD milestones and commercial needs.
* Core techniques: Apply techniques such as CVS, HPLC/UPLC, GPC, % solids, titrations, potentiostatic measurements, surface tension, cloud point, densitometry, and rheology (and related wet/physical methods).
* Other techniques relevant: ICP-OES/ICP-MS for metals/impurities, UV-Vis, FTIR, NMR, IC, TOC, DSC/TGA, particle size/zeta potential, SEM/EDS
* Method validation, transfer, and sustainment: Author/maintain methods, validation protocols/reports, and ensure robust method transfer to R&D and Manufacturing as needed.
* Data integrity & documentation: Maintain high-quality written documentation (methods, validation, batch/lot data packages, change control / MOC) and ensure traceable, audit-ready records.
* Troubleshooting & investigations: Support root-cause investigations, out-of-spec troubleshooting, and customer complaint response in collaboration with Quality/Manufacturing.
* Statistical/data analysis: Use statistical tools to analyze method performance, capability, trends, and investigation data (DOE, GR&R, SPC as applicable).
* Safety & teamwork: Work safely with hazardous chemicals in a collaborative, fast-paced lab environment; communicate clearly in both informal updates and formal presentations.
Required qualifications
* Education: B.S. in Chemistry, Biology, Chemical Engineering, Materials Science, or related field.
* Experience: 3-5 years of hands-on experience in analytical chemistry supporting R&D/NPD, development engineering, manufacturing, or quality environments. (Experience characterizing small molecules, polymers, and/or inorganic/metal-containing chemistries is strongly valued.)
* Demonstrated ability to follow procedures with high repeatability, strong attention to detail, and commitment to safe lab practices.
* Strong written and verbal communication skills; able to translate data into clear technical conclusions and recommendations.
* Strong data analysis capability; JMP/Minitab (or similar) preferred.
Preferred qualifications
* Demonstrated success developing/validating new analytical methods and supporting method transfer.
* Experience supporting semiconductor materials (e.g., plating baths, photoresists, dielectrics, silicones, packaging polymers) and working across interdisciplinary teams.
* Six Sigma (Green/Black Belt) or demonstrated experience applying structured problem-solving tools.
Join our Talent Community to stay connected with us!
Qnity is an equal opportunity employer. Qualified applicants will be considered without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability or any other protected class. If you need a reasonable accommodation to search or apply for a position, please visit our Accessibility Page for Contact Information.
Qnity offers a comprehensive pay and benefits package. To learn more visit the Compensation and Benefits page.
We use Artificial Intelligence (AI) to enhance our recruitment process.
$100k-115k yearly est. Auto-Apply 6d ago
Research Associate/Associate Scientist, Assay Development
Spear Bio
Research and development technician job in Woburn, MA
Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.
Research Associate/Associate Scientist:
We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs.
This role is based onsite in our lab in Woburn, MA 5 days/wk.
Responsibilities:
Test and execute immunoassay workflows on high-throughput, semi-automated platforms
Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development
Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects
Assist in data analysis
Acquire necessary equipment and supplies for various projects
Qualifications:
Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab
Direct experience running biofluid-based immunoassays and qPCR experimentation is required
Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.)
Experience characterizing and troubleshooting immunoassays
Strong proficiency in molecular biology lab techniques
General Qualifications:
Self-motivated and ability to perform complex tasks in an effective manner
Ability to follow instructions and grow in a mentorship setting
Excellent organizational and documentation skills
Desire to learn and implement new technologies
Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team
Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position.
We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.
Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.
Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
$69k-97k yearly est. Auto-Apply 44d ago
iPSC Production Scientist - Biology
ZP Group 4.0
Research and development technician job in Medford, MA
Piper Health & Sciences is seeking a full-time iPSC Production Scientist to join a growing organization's Bio/Engineering Production team onsite at their Massachusetts location. The ideal candidate will have a strong biology background and hands-on experience in iPSC stem cell culture, differentiation, and QC within a pharmaceutical or biotech environment.
Responsibilities of the iPSC Production Scientist Include:
* Full-time onsite schedule: Monday-Friday, 9:00 AM - 5:00 PM
* Lead and support iPSC production and related lab activities
* Perform hands-on stem cell culture and differentiation
* Execute QC-related tasks in accordance with SOPs
* Maintain accurate lab documentation and records
* Support Bio/Engineering Production workflows
* Follow all safety, GMP, and GLP standards
Qualifications of the iPSC Production Scientist Include:
* Biology degree is strongly preferred (Biomedical Engineering degrees are NOT a fit)
* Proven hands-on experience with:
* iPSC cell culture
* Stem cell differentiation
* Quality Control (QC) processes
* Pharmaceutical or biotech industry experience preferred
Compensation of the iPSC Production Scientist Includes:
* Salary Range: $83,200.00 - $114,000.00 per year (equivalent to $40.00 - $55.00 per hour), based on experience and certifications.
* Comprehensive Benefits: CIGNA Medical, Dental, Vision; 401k through ADP and sick leave as required by law.
* Ability to work with a well renowned and growing organization that has a robust pipeline and quality culture.
This job opens for applications on 1/12/2026. Applications for this job will be accepted for at least 30 days from the posting date.
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$83.2k-114k yearly 10d ago
Research Technologist - Ordovas-Montanes Lab
Children's Hospital Boston 4.6
Research and development technician job in Boston, MA
This is an opportunity to join Ordovas-Montanes Lab, which specializes in understanding how inflammation drives memory formation in barrier tissues with the goal of developing new therapeutic avenues for human disease. This candidate will contribute to a collaborative project focused on mucosal immunity to respiratory infection and vaccination.
The candidate will work under the direct supervision of Dr. Jose Ordovas-Montanes and be closely integrated within a community of senior scientists, graduate students, and postdoctoral fellows. This position requires substantial technical expertise, the ability to troubleshoot specialized assays, and the capacity to support and train junior lab members as needed.
This role offers the opportunity to develop a wide range of experimental and computational skills while working in an interdisciplinary environment with access to resources across Boston Children's Hospital and Harvard Medical School. The ideal candidate is motivated to understand the biological principles underlying infection-induced inflammatory diseases and may be interested in pursuing future postgraduate education.
Key Responsibilities:
* Independently perform complex experimental workflows, help optimize protocols, and generate high-quality data for single-cell genomics and airway epithelial biology studies.
* Troubleshoot specialized assays.
* Support and train junior lab members as needed.
* Performs routine and highly specialized lab experiments using sophisticated and intricate research equipment and techniques. Performs and devises specialized experiments and research procedures, troubleshooting problems with own and other researchers' results.
* Assists other lab personnel with the use of specialized equipment and techniques within the lab.
Minimum Qualifications
Education:
* Bachelor's degree in biology, immunology, genomics, chemistry, or a related field is required. Master's degree preferred but not required.
Experience:
* Bachelor's and 4 years of relevant experience OR a Master's of Science and 2 years of relevant experience.
* Demonstrated experience performing mammalian cell culture, ideally primary airway epithelial culture or similar complex systems.
* Proficiency in molecular biology techniques.
* Proven ability to independently execute and troubleshoot complex laboratory workflows.
* Experience with single-cell RNA-sequencing methods and data analysis in R and/or python is preferred but not required.
The posted pay range is Boston Children's reasonable and good-faith expectation for this pay at the time of posting.
Any base pay offer provided depends on skills, experience, education, certifications, and a variety of other job-related factors. Base pay is one part of a comprehensive benefits package that includes flexible schedules, affordable health, vision and dental insurance, child care and student loan subsidies, generous levels of time off, 403(b) Retirement Savings plan, Pension, Tuition and certain License and Certification Reimbursement, cell phone plan discounts and discounted rates on T-passes. Experience the benefits of passion and teamwork.
$44k-55k yearly est. 41d ago
R&D Reliability Engineer - Electromechanical Systems & Testing
Formlabs 4.3
Research and development technician job in Boston, MA
A 3D printing technology company in Boston is seeking an R&D Reliability Engineer to ensure product robustness through comprehensive testing strategies. You will build and execute validation plans, analyze failure data, and collaborate with design teams to enhance reliability. The ideal candidate should be proficient with electromechanical systems and data analysis, and can implement tests in Python. This role offers a competitive salary and generous benefits, including equity opportunities.
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$84k-111k yearly est. 5d ago
Learn more about research and development technician jobs
How much does a research and development technician earn in Nashua, NH?
The average research and development technician in Nashua, NH earns between $70,000 and $150,000 annually. This compares to the national average research and development technician range of $55,000 to $125,000.
Average research and development technician salary in Nashua, NH
$103,000
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