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Research biochemist skills for your resume and career
15 research biochemist skills for your resume and career
1. Assay Development
Assay development is a process in molecular biology to test or measure the activity of a drug or biochemical substance in an organic sample or organism and to screen putative compounds to determine the interaction and/or modification of the target. The aim is to standardize the assay and to be able to use it repeatedly and reproducibly.
- Produced proteins in large scale for structure determination, HTS screens and in-vitro assay developments.
- Supported basic research by providing high quality purified monoclonal antibodies from mammalian, hybridoma culture for preclinical development and assay development.
2. Protein Analysis
- Study Director for regulatory studies requiring detailed GLP protein analysis for submission to Global regulatory agencies.
- Developed purification and characterization methods related to plant- and microbe-derived protein analysis and degradation.
3. R
R is a free software environment and a language used by programmers for statistical computing. The R programming language is famously used for data analysis by data scientists.
- Created R Shiny applications for variant analysis and data visualization to support complex queries, exploratory analysis, and result interpretation.
- Explored generalized linear models and generalized additive models using R statistical software and ArcGIS software.
4. Research Projects
- Acquired Skills: Management: Designed and supervised independent research projects.
- Performed statistical analyses for quantitative/qualitative research projects.
5. HPLC
- Conducted TNT extraction efficiency experiments using HPLC methodology.
- Developed both a radioactive TCA precipitation and HPLC assays for the Insulin Receptor Activator program to quantify bound vs. unbound substrate.
6. Data Analysis
- Worked extensively with data analysis/interpretation and presentation.
- Train and supervise undergraduate students in study design, assay development and validation, experiments, and data analysis and interpretation.
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An enzyme-linked immunosorbent assay or ELISA is an examination or test to measure and detect a person's specific antigen, antibodies, and protein. This type of test will identify if the sample component is infected with a relative disease or condition such as HIV infection, anemia, Zika Virus, and Lyme disease with just a single experiment.
- Performed ELISA assay platform optimization, validation, and transfer assessments to maximize quality and quantity of clinical trial data reporting.
- Evaluated compounds for cancer research programs in the cell-based ECL and ELISA assays.
8. RT-PCR
- Established single-cell nested RT-PCR technique.
- Designed and optimized RT-PCR and real time RT-PCR assays.
9. Sops
A standard operating procedure or simply SOP is a particular operation that needs to be done in accordance with the rules and guidelines of a company or an industry. It is an important way for a company to run smoothly, especially in small businesses. It is like a practice wherein everything an individual or an employee is under a particular standard that is implemented.
- Developed, optimized protocols and recorded SOPs.
- Created SOPs for operation, CIP and troubleshooting of fermenters.
10. RNA
A Ribonucleic acid (RNA) has a vital role in determining the biological macromolecule commonly found in all bodily cells. It is the synthesis of protein, carriers message instruction from the Deoxyribonucleic acid or DNA. RNA is a kind of single-stranded cell that has different forms. It allows the molecule to go back and forth to its original condition.
- Studied hormonal regulation of animal cell gene expression Purified and characterized yeast mitochondrial RNA polymerase
- Sub-cloned and end-labeled neuropeptide cDNAs for use as templates for RNA probes in the ribonuclease protection assay.
11. SDS-PAGE
- Characterized purified product by SDS-PAGE, Western blot and BCA/Bradford.
- Ensured quality of purified protein by SEC-HPLC, SDS-PAGE and LAL analysis.
12. Cell Lines
- Constructed monitor vectors to measure Flu virus replication in cell lines and established two 293 cell lines for Flu virus.
- Established an indicating gene (SEAP) expressing method to detect delivered gene expression in cell lines and animals.
13. DNA
Deoxyribonucleic acid, or only DNA, which is considered the king of molecules, is a macromolecule that contains the main component of chromosomes. Shaped like a double helix, DNA is usually found in the nucleus of a cell. It is a type of material that transports characteristics in many forms, developed in nucleotides around one another.
- Conducted recombinant DNA technology studies to support both HIV and Hepatitis A Vaccine programs.
- Investigated DNA / protein homologies between species using DNA analysis software.
14. FDA
The Food and Drug Administration (FDA) is a division of the US Department of Health and Human Services that regulates the production and sale of food, pharmaceutical products, medical equipment, and other consumer goods, as well as veterinary medicine. The FDA is now in charge of overseeing the manufacture of products like vaccines, allergy treatments, and beauty products.
- Prompt method development of protein aggregation assays, which enabled process and formulation groups to make FDA approved products.
- Coordinated IQ/OQ/PQ testing for new equipment and maintenance of PQ testing as per FDA guidelines.
15. Analytical Assays
- Trouble shooting for Process and Manufacturing groups using analytical assays.
- Support R&D efforts through development/implementation of analytical assays for small molecule drug candidates.
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Dr. Christopher Nygren Ph.D.
Associate Professor, University of Pittsburgh
What soft skills should all research biochemists possess?
Alexandra (Sasha) Ormond Ph.D.
Associate Professor of Chemistry, Director of Dual Degree Engineering, Meredith College
What hard/technical skills are most important for research biochemists?
Alexandra (Sasha) Ormond Ph.D.
Associate Professor of Chemistry, Director of Dual Degree Engineering, Meredith College
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Assistant Department Chair, Geology, Auburn University
What type of skills will young research biochemists need?
What technical skills for a research biochemist stand out to employers?
List of research biochemist skills to add to your resume

The most important skills for a research biochemist resume and required skills for a research biochemist to have include:
- Assay Development
- Protein Analysis
- R
- Research Projects
- HPLC
- Data Analysis
- Elisa
- RT-PCR
- Sops
- RNA
- SDS-PAGE
- Cell Lines
- DNA
- FDA
- Analytical Assays
- Enzymes
- Biomarkers
- Molecular Biology Techniques
- QC
- HPV
- GMP
- Clinical Trials
- Gene Expression
- Cell-Based Assays
- HTS
- Electrophoresis
- Basic Research
- Clinical Studies
- GLP
- Immunoassay
- NMR
- SAR
- Clinical Samples
- Hazardous Materials
- Clinical Development
- Pharmacokinetics
- PowerPoint
- Data Management
- Lims
Updated January 8, 2025