Research fellow jobs in Lakewood, WA - 556 jobs

Meta's mission is to give people the power to build community and bring the world closer together. Through our family of apps and services, we're building a different kind of company that connects billions of people around the world, gives them ways to share what matters most to them, and helps bring people closer together. Whether we're creating new products or helping a small business expand its reach, people at Meta are builders at heart. Our global teams are constantly iterating, solving problems, and working together to empower people around the world to build community and connect in meaningful ways. Together, we can help people build stronger communities - we're just getting started. Our team at Meta Reality Labs is dedicated to exploring new technologies and integrating them into custom image sensors. As an intern, you will have the opportunity to work on projects that push the boundaries of what is possible in the field of image sensors and contribute to the development of AR/VR devices. Our internships are twelve (12) to sixteen (16), or twenty-four (24) weeks long and we have various start dates throughout the year. Minimum Qualifications * Currently has or is in the process of obtaining a Ph.D. degree in the fields of Electrical Engineering, Computer Science, or related field * Research experience in one or more of the following aspects of Image Sensors: Device physics and fabrication, Analog/mixed signal circuit design, Imaging systems (camera, ISP, algorithm) * Experience with analog/mixed-signal circuit design CAD tools such as Cadence Virtuoso * Successful tape-out and hands-on bench testing experience * Simulation and modeling experience with scripting languages such as Python, Matlab * Must obtain work authorization in the country of employment at the time of hire and maintain ongoing work authorization during employment Preferred Qualifications * 3+ years of experience in circuit design * Tape out experience with advanced technology nodes * Image signal processing experience (noise reduction, HDR processing) * Proven track record of achieving significant results as demonstrated by grants, or fellowships, as well as first-authored publications in major conferences and journals such as IISW, IEDM, VLSI, ISSCC, JSSC, TED Responsibilities * Investigate and propose novel pixel architectures and sensor architectures * Perform pixel schematic/layout design and simulation in advanced process nodes * Architect and design readout and processing circuits to achieve ultra-low power consumption * Characterize image sensors and experiment with new image sensor operation schemes * Collaboration with and support of other researchers across various disciplines * Communication of research agenda, progress and results About Meta Meta builds technologies that help people connect, find communities, and grow businesses. When Facebook launched in 2004, it changed the way people connect. Apps like Messenger, Instagram and WhatsApp further empowered billions around the world. Now, Meta is moving beyond 2D screens toward immersive experiences like augmented and virtual reality to help build the next evolution in social technology. People who choose to build their careers by building with us at Meta help shape a future that will take us beyond what digital connection makes possible today-beyond the constraints of screens, the limits of distance, and even the rules of physics. Equal Employment Opportunity Meta is proud to be an Equal Employment Opportunity employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, reproductive health decisions, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, genetic information, political views or activity, or other applicable legally protected characteristics. You may view our Equal Employment Opportunity notice here. Meta is committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans in our job application procedures. If you need assistance or an accommodation due to a disability, fill out the Accommodations request form.

About the Role We're looking for an experienced Staff / Senior Staff Research Scientist to push the boundaries of applied machine learning and AI at Opendoor. While this role will have a significant impact on our valuation systems - ensuring we provide the most accurate and transparent pricing possible - the scope goes well beyond pricing. You'll work across a range of challenging ML problems, from multi-modal modeling to operational optimization, helping us rethink how we use structured and unstructured data to make better decisions for our customers. What You'll Need Strong software engineering and coding skills in Python, with experience contributing to production codebases 9+ years of experience developing and deploying ML models end-to-end - from research and prototyping to implementation in production systems Hands-on experience with deep learning architectures, including ConvNets, Transformers, or similar Advanced degree (MS or PhD) in computer science, statistics, mathematics, or a related quantitative field Solid foundation in statistics and experimental design Strong communication and collaboration skills - you're comfortable working with cross-functional stakeholders and can communicate technical ideas clearly Nice to Have Familiarity with Pyspark and distributed data processing Background in search, recommendation systems, or personalization Experience working with large language models (LLMs) or vision-language models (VLMs) A genuine interest in real estate - no prior experience required, but you'll engage deeply with housing data What You'll Do Design and deploy architectural improvements to our deep neural network (DNN)-based home valuation models Build interpretable ML models that can help us explain pricing decisions to customers Incorporate unstructured data - like images, videos, or text - into our forecasting and valuation pipelines using cutting-edge AI models (LLMs, VLMs, etc.) Collaborate with Engineering and Ops to enhance our human-in-the-loop pricing systems Improve the feature engineering and model training pipelines that power our production systems Rethink our risk and optimization models using real-world data and domain insight We're a small, nimble team - there's ample opportunity to work across the entire research and modeling stack. Compensation The base pay range for this position is $238,400 - $327,800 annually, plus RSUs and bonuses. Pay within this range varies by work location and may also depend on your qualifications, job-related knowledge, skills, and experience. We also offer a comprehensive package of benefits including unlimited PTO, medical/dental/vision insurance, life insurance, and 401(k) to eligible employees. At Opendoor our mission is to tilt the world in favor of homeowners and those who aim to become one. Homeownership matters. It's how people build wealth, stability, and community. It's how families put down roots, how neighborhoods strengthen, how the future gets built. We're building the modern system of homeownership giving people the freedom to buy and sell on their own terms. We've built an end-to-end online experience that has already helped thousands of people and we're just getting started.

Clinical Research Investigator DM Clinical Research, the largest privately-owned research management organization in the Houston area and one of the top 50 in the country, is looking for an Investigator for our sites in Seattle, WA. This individual will conduct all clinical trials (studies) according to ICH, GCP, local regulations, study protocols, and company processes. Responsibilities Ensures the medical well-being and safety of the participants through the safe performance and execution of the studies. Assists in maintaining clinical oversight and quality on the studies registered on and delivers on study targets, thereby contributing to the commercial success of the site. Reviews enrollment progress, pre-screening and screening success rates, screen failure rates, safety, and retention of participants. Interprets protocols and IB and participates in initiatives to strategize for patient recruitment. Carries out clinical evaluation and assessment of participants to ensure eligible participants are enrolled onto studies. Ensures and protects the welfare and safety of participants through ethical conduct. Fulfills and comply with all medical duties as per protocol, SOP/COP and ICH GCP and local regulations. Exercises meticulous attention to detail in documentation and patient care. Requirements Medical License (MD, DO) At least 2 years of experience as a Clinical Research Investigator. Spanish Bilingual a plus.

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets. Position Overview As a Research Associate III at Immunome, Inc., you will be a key contributor to our research and development initiatives, driving the optimization and delivery of antibody-drug conjugates (ADCs). In this role, you will design, produce, and characterize ADCs in support of program-specific objectives, while collaborating closely with cross-functional partners. Your expertise in bioconjugation will provide critical insights that help advance our therapeutic pipeline and strengthen our scientific capabilities. Responsibilities Research Design and Execution * Generate high quality ADCs to enable advancement of named programs. * Evaluate innovative bioconjugation and linker technologies. * Assess developability of discovery stage ADCs. * Work collaboratively with cross-functional teams to plan experiments aimed at advancing drug development projects. * Independently perform laboratory experiments in accordance with established protocols, maintaining the highest standards of scientific rigor, documentation, and data integrity. * Continuously optimize laboratory processes to improve workflow efficiency, reproducibility, and throughput. * Manage ADC inventory and coordinate delivery of samples to cross-functional partners. * Data Analysis and Interpretation: * Characterize biophysical properties of ADCs using various techniques, such as analytical SEC, HIC, PLRP, and LC-MS. * Interpret results and draw meaningful conclusions to guide decision-making. Project Collaboration * Collaborate with colleagues from diverse scientific disciplines to achieve project goals. * Participate in project team meetings, providing expertise and insights to drive projects forward. Continuous Learning and Development * Stay informed about the latest bioconjugation advancements in the ADC field. * Proactively seek opportunities for professional development and contribute to the scientific growth of the research team. Qualifications * BS or MS in Biochemistry, Chemistry, or related field. * Minimum of 5 years of experience (or 3 years of experience for MS) in preclinical drug development in the biotechnology or pharmaceutical industry. * Proficiency in bioconjugation techniques and demonstrated experience in ADC pre-clinical development is a requirement. Knowledge and Skills * Proficient in analytical techniques and purification methods relevant to biologics and ADC development (SEC, HIC, PLRP, and LC-MS, etc). * Experience in antibody engineering and protein modification is a plus. * Excellent communication skills, both written and verbal, to effectively collaborate with cross-functional teams and communicate scientific concepts to non-scientific stakeholders. * Proven ability to adapt to changing priorities and work in a fast-paced, dynamic environment. * Experience with Agilent OpenLab and Benchling is a plus. Please note, the internal title for this role is Research Scientist II, Bioconjugation Chemistry Washington State Pay Range $96,044 - $107,008 USD E/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish). Create a Job Alert Interested in building your career at Immunome, Inc.? Get future opportunities sent straight to your email. Create alert

**The Department of Anesthesiology & Pain Medicine has an outstanding opportunity for a Research Scientist/Engineer 4 to join their team.** The Raftery research group focuses on developing new methods and applications of metabolite profiling using a combination of mass spectrometry (MS) and NMR platforms which provide a broad-based approach for biomarker discovery and systems biology research. The main purpose of this position is to analyze the metabolomics data that we generate, as well as complementary, available genomic or proteomic data for several projects focused on understanding the biology of aging. The aging studies focus on numerous organisms, including humans, dogs, flies and through the Nathan Shock Center, mice or other model organisms. The Department of Anesthesiology & Pain Medicine has an outstanding opportunity for a Research Scientist/Engineer 4 to join the Raftery lab to investigate the biology of aging using metabolomics, genomics, and systems biology. This position is at 100% FTE. The RSE4 will need a high level of skill in oral and written scientific communication and extensive knowledge of systems biology, statistics and computational methods. The position will focus primarily on the statistical and pathway analysis of the complex metabolite data, including generating creative and new methods of analysis of the data, but will also involve biological interpretation and assisting other researchers with study design. The Scientist will be responsible for generating draft manuscripts and in assisting with proposal writing. **DUTIES AND RESPONSIBILITIES** **_Research Responsibilities = 70%_** + Consult and coordinate on research efforts and study design with collaborators focused on aging. + Write, develop, and modify data analysis code and workflows. + Perform data transfer, data preparation, and cleanup of high-dimensional experimental data. + Perform advanced statistical analysis of high-dimensional experimental data. + Interpret findings within the biological context. + Contribute experimental hypotheses for new scientific inquiries and novel directions of research. + Assist researchers associated with the Shock Center pilot program by providing scientific feedback to enhance their research objectives. + Participate in and contribute to scientific meetings of the Nathan Shock Center. **_Prepare analytic results for reports, publications, and presentations = 30%_** + Initiate and/or contribute to the scientific writing of peer-reviewed publications. Contributeto scientific writing for grant applications. Communicatewith collaborators and the larger scientific community via research presentations. **MINIMUM REQUIREMENTS** + Master's degree in Genetics or Biochemistry and four years of relevant experience _Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration._ **A** **D** **DITIONAL REQUIREMENTS** + This position requires extensive systems biology, statistics, and computational methods knowledge as well as knowledge in the biology of aging. + A high level of skill in oral and written scientific communication, including presenting at national and international conferences, and authorship and co-authorship of publications and grants. + Extensive knowledge of statistical methods including multivariate and univariate analysis of large data sets, learning and predictive modeling, network analysis, and probabilistic approaches to test theories and develop hypotheses in systems biology. + Systems biology knowledge requires a foundation in biology ranging from a detailed understanding of genetics, biochemistry, and molecular biology to whole organism physiology, development, and population demography. Those elements are utilized in developing and testing theories of aging and other biological phenomena using high-dimensional metabolomics, genomics, knowledge-based networks, and other data type. **DESIRED QUALIFICATIONS** · This position is best served by someone who can work independently to facilitate collaboration between investigators working across different fields of aging, biology and chemistry. · A fundamental understanding of mass spectrometry and chemical analysis is highly desired as it greatly increases the breadth of collaborations with the UW Northwest Metabolomics Research Center. **Compensation, Benefits and Position Details** **Pay Range Minimum:** $99,996.00 annual **Pay Range Maximum:** $120,000.00 annual **Other Compensation:** - **Benefits:** For information about benefits for this position, visit ****************************************************** **Shift:** First Shift (United States of America) **Temporary or Regular?** This is a regular position **FTE (Full-Time Equivalent):** 100.00% **Union/Bargaining Unit:** UAW Research **About the UW** Working at the University of Washington provides a unique opportunity to change lives - on our campuses, in our state and around the world. UW employees bring their boundless energy, creative problem-solving skills and dedication to building stronger minds and a healthier world. In return, they enjoy outstanding benefits, opportunities for professional growth and the chance to work in an environment known for its diversity, intellectual excitement, artistic pursuits and natural beauty. **Our Commitment** The University of Washington is committed to fostering an inclusive, respectful and welcoming community for all. As an equal opportunity employer, the University considers applicants for employment without regard to race, color, creed, religion, national origin, citizenship, sex, pregnancy, age, marital status, sexual orientation, gender identity or expression, genetic information, disability, or veteran status consistent with UW Executive Order No. 81 (*********************************************************************************************************************** . To request disability accommodation in the application process, contact the Disability Services Office at ************ or ********** . Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law (********************************************************* . University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.

Talus Bioscience, a venture-backed early-stage biotechnology company, is at the forefront of developing innovative therapies for incurable cancers. Driven by the belief that "nothing is undruggable," we harness cutting-edge proteomics and AI during the initial stages of discovery to unlock previously inaccessible targets in cancer. At Talus Bio, we combine functional proteomics, automated biology, and machine learning to target hard-to-treat transcription factor proteins driving cancer. Exciting opportunities await at Talus Bio - your chance to be part of something transformative! Research Associate II Job Description Talus Bio is looking for a Research Associate II (RA II) to join our Biology / Drug Discovery team full-time in our Seattle office (this is an in-person role). This person will be naturally curious, results-driven, and eager to work in a small preclinical biotech environment. The person in this role will play a key role in supporting our drug discovery programs targeting transcription factors implicated in cancer, working closely with a multidisciplinary team of scientists to design, execute, and analyze experiments, providing critical data to advance our lead compounds through preclinical stages. This role is part of a pioneering team contributing to the development of innovative cancer therapies from the ground up. This role will assist with hit validation from our primary screens, primarily through running multiplex RT-qPCR and other assays as viability or reporter assays. It will involve extensive optimization, assay development, and medium-throughput testing and work on multiple projects simultaneously. Responsibilities Conduct laboratory experiments to support the discovery and characterization of small molecules targeting transcription factors in cancer. Perform cell-based assays (e.g., cell viability, apoptosis, and reporter assays) to evaluate compound efficacy and mechanistic effects on transcription factors. Utilize molecular biology techniques (e.g., PCR, RT-qPCR, CRISPR, RNAi) to analyze gene expression and validate targets Contribute to the design, optimization, and execution of assays for high-throughput screening and compound profiling. Maintain detailed and accurate laboratory notebooks and records in compliance with company policies. Collaborate effectively with team members to solve technical challenges and streamline workflows. Stay current on relevant literature and emerging technologies in cancer biology, transcription factor research, and drug discovery Ability to multitask and advance multiple projects at different stages simultaneously from assay development to compound screening Maintain complete, timely, and accurate records of all experiments performed, including experimental design, procedures, and data analysis Analyze/interpret experimental data and communicate the results and recommendations to other team members (oral and written formats) Must be highly-motivated and able to work independently QualificationsRequired Bachelor's degree in Molecular Biology, Biochemistry, Cancer Biology, or a related field Minimum of 3 years of laboratory experience with cell culture techniques and handling cancer cell lines, including a minimum of 2 years of hands-on research experience running RT-qPCR assays (including selection and custom-design of oligos). Alternately: Master's degree with at least 1 year of experience in a similar role Preferred Prior experience in drug discovery, especially with transcription factor targets in cancer. Familiarity with high-throughput screening assays and/or experience in hit-to-lead workflows. Familiarity with cell-based assays (e.g., cell viability, reporter assays for evaluating compound effects. Working knowledge of data analysis software (e.g., GraphPad Prism, Excel) and basic statistical methods. This position is only open to applicants that are legally authorized to work in the US. A cover letter is required to be submitted with the CV for all applicants. Our Commitment to Diversity & Inclusion Talus Bio is committed to creating a diverse, inclusive, and empowering workplace. We believe that having employees, interns, and contractors with diverse backgrounds enables Talus Bio to better meet our mission and serve healthcare communities around the world. We recognize that opportunities in the life sciences have historically excluded and continue to disproportionately exclude Black and Indigenous people, people of color, people from working class backgrounds, people with disabilities, and LGBTQIA+ people. We welcome all people including cisgender, transgender, agender, and intersex and are inclusive of non-binary folx. We strongly encourage individuals with these identities to apply. Salary and Benefits The salary range for this position is $80,000 - $90,000 per year. Despite being a small early-stage biotech, Talus Bio's first priority is the safety and wellbeing of all our employees and their families, both inside and outside of the lab. As part of this commitment, we have put a great deal of thought and care into developing a cost-effective and comprehensive benefits package for our team. Our benefits package includes but is not limited to the following: Medical/dental/vision insurance coverage with 100% company-paid premiums for employees and 50% company-paid for dependents $124/month commuter and transportation reimbursement program 401(k) plan with a 4% Talus Bio contribution (regardless of employee contribution) Basic Life and AD&D insurance coverage with 100% company-paid premiums Short- and Long-Term Disability insurance coverage with 100% company-paid premiums Paid sick leave (52 hours/year) 4 weeks of paid time off PLUS a paid end-of-year shutdown between Christmas Day and New Year's day 10 paid holidays Weekly meals, snacks, and drinks Flexible working hours Flexible working environment and schedule Yearly company retreat and quarterly company events Our Commitment to Diversity & Inclusion Talus Bio is committed to creating a diverse, inclusive, and empowering workplace. We believe that having employees, interns, and contractors with diverse backgrounds enables Talus Bio to better meet our mission and serve healthcare communities around the world. We recognize that opportunities in the life sciences have historically excluded and continue to disproportionately exclude Black and Indigenous people, people of color, people from working class backgrounds, people with disabilities, and LGBTQIA+ people. We welcome all people including cisgender, transgender, agender, and intersex and are inclusive of non-binary folx. We strongly encourage individuals with these identities to apply. Talus Bioscience, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Job Posted by ApplicantPro

AltPep Corporation is a biomedical company based along Seattle's Lake Union developing groundbreaking disease-modifying treatments and detection tools for amyloid diseases by targeting a novel early molecular trigger: alpha sheet oligomers. Our lead programs focus on Alzheimers and Parkinsons diseases, with other amyloid diseases on the horizon. AltPeps goal is to change the course of these debilitating diseases that affect over a billion people around the globe. AltPep draws its origins to Dr. Valerie Daggett's lab at the University of Washington's Bioengineering Department. We are looking for additional team members to join us at our state-of-the-art, headquarters located on the Eastside of Lake Union in Seattle. About this Role We are seeking a meticulous and dynamic Research Associate to join our team. You will be responsible for conducting and supporting laboratory research, including peptide synthesis, characterization (spectroscopy, biophysical, etc.), formulation activities, bioanalytical (pharmacokinetics) experiments, and stability studies, while ensuring the highest standards of quality and precision. Your contributions will be critical to the success of our research and development efforts, and you will have opportunities to work both independently and collaboratively within our innovative team. What Youll Do: Characterize peptides by UHPLC, mass spectrometry, circular dichroism, etc. Engage in chemical synthesis and peptide modifications to meet research and development objectives. Operate both manual and automated solid-phase peptide synthesis systems. Conduct (prep- and semi-prep) HPLC purification of peptides. Support novel Drug Product formulation development Support bioanalytical experiments and stability studies Troubleshoot and maintain instrumentation to ensure smooth laboratory operations. Maintain rigorous quality of experimental details outlined in Standard Operating Procedures (SOPs). Document research findings meticulously in lab books and records. Work both independently and collaboratively within an innovative team to achieve project goals. Prioritize and organize workflow to manage multiple tasks efficiently. Maintain a clean and orderly laboratory environment. Analyze and interpret data and generate reports Regularly communicate results, in written form and oral presentations, to the rest of the team and occasionally to senior management and in All-Company meetings. What You Bring: Must Haves: Bachelor's degree in chemistry, chemical engineering, biochemistry, bioengineering, or a related field. Experience in instrumental analysis using HPLC, UHPLC, and LC-MS. Ability to conduct quantitative analysis and apply quality control criteria effectively. Meticulous record-keeping abilities and attention to detail. Flexibility to adapt to a fast-paced and dynamic work environment and responsiveness to quick changes in tasks/priorities. Ability to learn rapidly and implement new laboratory techniques as needed Strong organizational skills to manage multiple tasks and prioritize workflow. What Will Separate You From the Rest: 2+ years of post-graduate experience in a relevant field, with previous biotech experience being a plus. Hands-on experience with solid-phase peptide synthesis and HPLC purification. Experience with productivity and scientific software, including ChemDraw /Marvinsketch Familiarity with PubMed and other information sources for pharmaceuticals. Ability to work independently while also valuing team collaboration. Knowledge of Quality Management Systems. Ability to learn and implement new analytical and synthetic chemistry techniques. Effective communication practices with peers and senior personnel. Flexible approach to structure and workflow management. Commitment to maintaining high standards of precision and cleanliness in laboratory work. Debilitating diseases such as Alzheimer's and Parkinson's affect more than a billion people worldwide. Drawing upon decades of academic research, AltPep was founded to create groundbreaking tools to detect and treat such diseases. Although a young company, AltPep has been recognized for its scientific accomplishment and potential. While still small and nimble, we have grown to a team of thirty talented individuals dedicated to improving the lives of billions. We continue to grow and are looking for talented people to join the team and help us accomplish our mission. We offer competitive compensation to those joining our fight. The compensation range for a Research Associate is $78,000 - $88,000, depending on experience. AltPep takes care of its employees and offers generous stock options, medical, vision, and dental coverage for its employees and their dependents. We understand, and value, life outside of work and offer competitive PTO so you can rest and recharge.

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are looking for a creative and motivated individual to execute and improve our Computational Protein Design pipeline using data-driven approaches to augment our first-in-class multi-specific biological programs. The ideal candidate will have experience applying computational methods to design novel peptides and proteins, with expertise in structural modeling, prediction, and optimization. Responsibilities: * Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach * Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms * Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process * Analyze, interpret, document, and present data to the scientific and leadership team * Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision Qualifications: * PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field * 8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required * Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger) * Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET) * Proven contribution to therapeutic antibody development and selection is desirable; design and validation of novel biologically relevant antibodies are highly desirable Compensation and Benefits: The expected base salary range for this position is $80,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are looking for a creative and motivated individual to execute and improve our Computational Protein Design pipeline using data-driven approaches to augment our first-in-class multi-specific biological programs. The ideal candidate will have experience applying computational methods to design novel peptides and proteins, with expertise in structural modeling, prediction, and optimization. Responsibilities: Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process Analyze, interpret, document, and present data to the scientific and leadership team Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision Qualifications: PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field 8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger) Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET) Proven contribution to therapeutic antibody development and selection is desirable; design and validation of novel biologically relevant antibodies are highly desirable Compensation and Benefits: The expected base salary range for this position is $80,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

Program Description In October 2021, Washington Emergency Care Physicians (WECP) proudly opened the first Pacific Northwest-based emergency medicine post graduate program for advance practice providers (APPs). The Program is specifically designed for physician assistants and nurse practitioners who are interested in a life-long career in emergency medicine with training sites in the Puget Sound through Tacoma Emergency Care Physicians (TECP), a subsidiary of WECP. Program Objectives To provide exceptional training and experience for APP professionals to have a successful career in any emergency department setting. To prepare candidates well for recognized emergency medicine APP examinations (NCCPA-CAQ for physician assistants, AANPCB Boards for nurse practitioners) Curriculum Fifteen (15) months program duration with over 3000 hours of post graduate training Close to 2400 hours of clinical training Over 300 hours of didactics to include over an introductory bootcamp followed my weekly activities that include conferences, meetings, case presentations, ultrasound training, procedure lab or simulation. Over 400 hours of independent study to include case review & presentation preparation, assigned CME and readings, and scholarly research project. Expected commitment of 50 hours per week of the above activities Phased Training with increasing levels of expected competency and confidence. Post Graduate APP 0: Pre-Boot Camp: 37 hours of on-line Emergency Medicine CME months before start of Program Boot Camp: First 2 weeks at start of Program Post Graduate APP 1: Six (6) months of ED clinical shifts in low acuity zones Post Graduate APP 2: Two and half (2.5) months of external rotations - Trauma (4 wks), Peds UCC & ED(4 wks), Ophthalmology/Critical Care/Interventional Rad(1.5 wks), Vacation(1wk) Post Graduate APP 2: Six (6) months of ED clinical shifts in high acuity zones Continuing Medical Education Required 150+ CME hours (provided and paid for by Program) Original EM Boot Camp on-line course, to be completed before start of program EMRAP subscription for duration of program DynaMed subscription ATLS, PALS Faculty Advisor & Mentor will be assigned to each post graduate candidate Regularly scheduled monthly meetings with Faculty Advisor Advisor to monitor progress and identify strengths/areas of improvement Advisor with candidate will develop individualized plan to ensure continued growth and development Senior Post Grad APPs are expected to mentor Junior Postgrads. Two (2) classes per year Fall - October 1st with 2 candidates Spring - April 1st with 2 candidates Training Locations All sites are part of MultiCare Health Systems Puget Sound: MultiCare Tacoma General (Level 2 Trauma, primary cardiac & stroke), Allenmore (Level 4 Trauma), and Covington Hospitals Admission requirements Must have graduated from an accredited PA/NP school Must be certified/licensed in Washington State after 4 weeks of starting program Must be able to evaluate and treat both pediatric and adult patients Must be willing to relocate to the Puget Sound for duration of program. Must be ACLS and PALS certified for duration of program Compensation & Benefits Salary: $65,780 per year ($82,150 for the 15-month Term) Reimbursement for licensing, certification, credentialing fees Benefits: medical and dental insurance, short-term disability insurance, 80 hours of PTO Eligible for retirement benefits if permanently hired after completion of program How to Apply Submit you most current Curriculum Vitae on ******************************************** Submit personal statement explaining why you are applying to the program along with your long-term professional goals Send three (3) letters of recommendation to the Program Director - to be sent directly from the authors of the letters. At least one letter must be from school director or faculty. Send your PA/NP school transcripts to the Program Director. Selected applicants will be asked to participate in an initial interview using a virtual video conference format. From those, applicants will be further selected to advance to a secondary in-person interview in Tacoma, WA Application Timeline Preliminary interviews will be scheduled once submitted application is completed (which include Letters of Recommendation) Spring class: please submit application with LORs by June 1st (10 months prior to start) Fall class: please submit application with LORs by December 1st (10 months prior to start). Frequently Asked Questions Weblink Contact Information Jaime Delcampo, MD, FACEP Program Director ***************************** ************** Cody Balogh, PA-C Assistant Program Director ************************** Joe Montgomery, PA-C Core Faculty/ Advisor ******************************** Amanda Stalder, PA-C Core Faculty/ Advisor *****************************

We are the leading oncology CRO, developing novel treatments for patients that need them most. Our team is fully dedicated to oncology - it is all we do - combining innovation and expertise to quickly move medicines from preclinical development into clinical trials. Adaptive and forward-thinking - we guide our client's therapy through the most critical development milestones from the lab to planning their regulatory and clinical strategy. Our ultimate goal? To help patients. Position Summary: The Flow Cytometry Research Associate llI executes and provides support for sample processing, acquisition, and data analysis in preclinical and/or clinical development within a Good Laboratory Practice (GLP) / Washington State Medical Test Site/ CAP Accredited environment. Essential Functions: * Interprets and follows, with accuracy, both study and flow cytometry protocols. * Prepares and run samples for flow cytometry analysis. * Independently performs tissue culture activities. * Maintains detailed and organized laboratory notes, documents, and files. * Performs quality control review and verification of scientific data. * Works with laboratory leadership to properly prepare for and execute assigned studies and protocols. * Maintains and calibrates lab equipment daily and/or weekly, including but not limited to the flow cytometer. * Prepares various solutions for stock or project use. * Performs QC and verification of flow cytometry data and/or maintenance records. * Independent troubleshooting of data and various pieces of equipment * Participates in team and scientific meetings as appropriate. * Work in a team-oriented environment and as well as independently. * Suggests topics and prepares data for poster presentations. * Adheres to protocols and standard operating procedures. * Develop standard operation procedures, as appropriate. * Perform other duties as assigned. Job Requirements: * 7-15 years Flow Cytometry experience and Bachelor's Degree/Biotechnology Certificate in science required or Master's degree with 2-4 years flow cytometry experience. * Experience in tissue/cell culture and aseptic technique. * Flexibility to adjust work hours as needed, including periodic late evenings and rotating Saturday coverage. Required Specialized/Technical Skills: * Proficiency in Microsoft Office * Experience in a Good Laboratory Practice (GLP)/CAP setting. * Strong communication skills, both written and verbal. * Experience communicating with a variety of individuals and personality types is preferred. * Strong time management skills. * Ability to work as a team and independently. * Good at multitasking and detail oriented TD2 is an equal opportunity employer and does not discriminate on the basis of race, color, national origin, creed, disability, veteran's status, gender, sexual orientation, gender identity, or gender expression. #LI-TD2

The discovery immunology research team is seeking a highly motivated Principal Research Associate. This is a laboratory-based role where the successful candidate will contribute directly to research efforts by designing, executing, and analyzing experiments related to immune mechanisms, target validation, and therapeutic development. The position requires strong attention to detail and ability to multitask while working in a highly collaborative environment. Key Duties and Responsibilities: Isolate, culture, and manipulate primary human immune cells and cell lines. Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays. Troubleshoot experiments and optimize protocols. Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records. Collaborate with scientists across discovery teams to achieve project goals. Prepare data for internal reports and presentations for internal meetings. Perform other duties as needed. Knowledge and Skills: Hands-on tissue culture experience, including the isolation and maintenance of primary human immune cells and human cell lines. Experience with nucleic acid techniques to quantify gene expression such as PCR, qPCR, and RNA sequencing. Experience with a variety of cell-based immunology assays to interrogate immune cell phenotype and function including multicolor flow cytometry and Incucyte assays. Experience measuring soluble analytes such as by ELISA, Luminex, or MSD. Critical thinking and self-reliance to solve tasks independently or ask questions. Strong organizational skills and attention to detail. Willingness and ability to work in a highly collaborative environment. Foundational knowledge of immunology and an eagerness to learn new techniques and skills. Strong analytical skills and proficiency in the following software packages: Microsoft Office, GraphPad Prism, FlowJo and Methodical Mind Analysis Software. Education and Experience: Master's degree (or equivalent degree) in biological sciences and 2+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) in biological sciences and 5+ years of relevant employment experience Pay Range: $92,900 - $139,300 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

About the Team: The commerce industry has seen tremendous growth in recent years and has become a hotly contested space amongst leading Internet companies, and its future growth can not be underestimated. We aim to bring discovery, inspiration, and joy back to shopping by making TikTok the commerce channel of choice for merchants, creators, and affiliates. We are looking for talented individuals to join our team in 2026. As a graduate, you will get opportunities to pursue bold ideas, tackle complex challenges, and unlock limitless growth. Launch your career where inspiration is infinite at TikTok. Successful candidates must be able to commit to an onboarding date by end of year 2026. Please state your availability and graduation date clearly in your resume. Candidates can apply to a maximum of two positions and will be considered for jobs in the order you apply. The application limit is applicable to TikTok and its affiliates' jobs globally. Applications will be reviewed on a rolling basis - we encourage you to apply early. Responsibilities: * Analyze E-Commerce businesses, focusing on traffic efficiency, user behavior, and merchant operations. Independently undertake special analyses on merchant growth, traffic conversion, creator/content growth, and user behavior. * Develop short-term and long-term scale and revenue targets. * Provide regular reports and insights to facilitate data-driven decision-making. * Monitor and analyze various operating indicators and drivers of the e-commerce operations team on a daily basis. * Leverage insights from analysis to make informed recommendations for future business strategies.Minimum Qualifications: * Final year or recent graduate in MBA. * Have good communication and coordination skills, excellent logical thinking ability, able to quickly understand business. * Strong analytical skills and proficiency in data analysis tools such as SQL/Python. * Excellent communication skills and can effectively handle cross-functional collaboration. Preferred Qualifications: * Experience in e-commerce industry operation analysis, business analysis, data analysis, etc. * Background in Business, Analytics, Mathematics, or a related field.

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets. Position Overview As a Research Associate III at Immunome, Inc., you will be a key contributor to our research and development initiatives, driving the optimization and delivery of antibody-drug conjugates (ADCs). In this role, you will design, produce, and characterize ADCs in support of program-specific objectives, while collaborating closely with cross-functional partners. Your expertise in bioconjugation will provide critical insights that help advance our therapeutic pipeline and strengthen our scientific capabilities. Responsibilities Research Design and Execution Generate high quality ADCs to enable advancement of named programs. Evaluate innovative bioconjugation and linker technologies. Assess developability of discovery stage ADCs. Work collaboratively with cross-functional teams to plan experiments aimed at advancing drug development projects. Independently perform laboratory experiments in accordance with established protocols, maintaining the highest standards of scientific rigor, documentation, and data integrity. Continuously optimize laboratory processes to improve workflow efficiency, reproducibility, and throughput. Manage ADC inventory and coordinate delivery of samples to cross-functional partners. Data Analysis and Interpretation: Characterize biophysical properties of ADCs using various techniques, such as analytical SEC, HIC, PLRP, and LC-MS. Interpret results and draw meaningful conclusions to guide decision-making. Project Collaboration Collaborate with colleagues from diverse scientific disciplines to achieve project goals. Participate in project team meetings, providing expertise and insights to drive projects forward. Continuous Learning and Development Stay informed about the latest bioconjugation advancements in the ADC field. Proactively seek opportunities for professional development and contribute to the scientific growth of the research team. Qualifications BS or MS in Biochemistry, Chemistry, or related field. Minimum of 5 years of experience (or 3 years of experience for MS) in preclinical drug development in the biotechnology or pharmaceutical industry. Proficiency in bioconjugation techniques and demonstrated experience in ADC pre-clinical development is a requirement. Knowledge and Skills Proficient in analytical techniques and purification methods relevant to biologics and ADC development (SEC, HIC, PLRP, and LC-MS, etc). Experience in antibody engineering and protein modification is a plus. Excellent communication skills, both written and verbal, to effectively collaborate with cross-functional teams and communicate scientific concepts to non-scientific stakeholders. Proven ability to adapt to changing priorities and work in a fast-paced, dynamic environment. Experience with Agilent OpenLab and Benchling is a plus. Please note, the internal title for this role is Research Scientist II, Bioconjugation Chemistry Washington State Pay Range $96,044 - $107,008 USD E/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).

AltPep Corporation is a biomedical company based along Seattle's Lake Union developing groundbreaking disease-modifying treatments and detection tools for amyloid diseases by targeting a novel early molecular trigger: alpha sheet oligomers. Our lead programs focus on Alzheimer's and Parkinson's diseases, with other amyloid diseases on the horizon. AltPep's goal is to change the course of these debilitating diseases that affect over a billion people around the globe. AltPep draws its origins to Dr. Valerie Daggett's lab at the University of Washington's Bioengineering Department. We are looking for additional team members to join us at our state-of-the-art, headquarters located on the Eastside of Lake Union in Seattle. About this Role We are seeking a meticulous and dynamic Research Associate to join our team. You will be responsible for conducting and supporting laboratory research, including peptide synthesis, characterization (spectroscopy, biophysical, etc.), formulation activities, bioanalytical (pharmacokinetics) experiments, and stability studies, while ensuring the highest standards of quality and precision. Your contributions will be critical to the success of our research and development efforts, and you will have opportunities to work both independently and collaboratively within our innovative team. What You'll Do: Characterize peptides by UHPLC, mass spectrometry, circular dichroism, etc. Engage in chemical synthesis and peptide modifications to meet research and development objectives. Operate both manual and automated solid-phase peptide synthesis systems. Conduct (prep- and semi-prep) HPLC purification of peptides. Support novel Drug Product formulation development Support bioanalytical experiments and stability studies Troubleshoot and maintain instrumentation to ensure smooth laboratory operations. Maintain rigorous quality of experimental details outlined in Standard Operating Procedures (SOPs). Document research findings meticulously in lab books and records. Work both independently and collaboratively within an innovative team to achieve project goals. Prioritize and organize workflow to manage multiple tasks efficiently. Maintain a clean and orderly laboratory environment. Analyze and interpret data and generate reports Regularly communicate results, in written form and oral presentations, to the rest of the team and occasionally to senior management and in All-Company meetings. What You Bring: Must Haves: Bachelor's degree in chemistry, chemical engineering, biochemistry, bioengineering, or a related field. Experience in instrumental analysis using HPLC, UHPLC, and LC-MS. Ability to conduct quantitative analysis and apply quality control criteria effectively. Meticulous record-keeping abilities and attention to detail. Flexibility to adapt to a fast-paced and dynamic work environment and responsiveness to quick changes in tasks/priorities. Ability to learn rapidly and implement new laboratory techniques as needed Strong organizational skills to manage multiple tasks and prioritize workflow. What Will Separate You From the Rest: 2+ years of post-graduate experience in a relevant field, with previous biotech experience being a plus. Hands-on experience with solid-phase peptide synthesis and HPLC purification. Experience with productivity and scientific software, including ChemDraw /Marvinsketch Familiarity with PubMed and other information sources for pharmaceuticals. Ability to work independently while also valuing team collaboration. Knowledge of Quality Management Systems. Ability to learn and implement new analytical and synthetic chemistry techniques. Effective communication practices with peers and senior personnel. Flexible approach to structure and workflow management. Commitment to maintaining high standards of precision and cleanliness in laboratory work. Debilitating diseases such as Alzheimer's and Parkinson's affect more than a billion people worldwide. Drawing upon decades of academic research, AltPep was founded to create groundbreaking tools to detect and treat such diseases. Although a young company, AltPep has been recognized for its scientific accomplishment and potential. While still small and nimble, we have grown to a team of thirty talented individuals dedicated to improving the lives of billions. We continue to grow and are looking for talented people to join the team and help us accomplish our mission. We offer competitive compensation to those joining our fight. The compensation range for a Research Associate is $78,000 - $88,000, depending on experience. AltPep takes care of its employees and offers generous stock options, medical, vision, and dental coverage for its employees and their dependents. We understand, and value, life outside of work and offer competitive PTO so you can rest and recharge.

Job Description SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. We are looking for a creative and motivated individual to execute and improve our Computational Protein Design pipeline using data-driven approaches to augment our first-in-class multi-specific biological programs. The ideal candidate will have experience applying computational methods to design novel peptides and proteins, with expertise in structural modeling, prediction, and optimization. Responsibilities: Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process Analyze, interpret, document, and present data to the scientific and leadership team Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision Qualifications: PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field 8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger) Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET) Proven contribution to therapeutic antibody development and selection is desirable; design and validation of novel biologically relevant antibodies are highly desirable Compensation and Benefits: The expected base salary range for this position is $80,000 - $180,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills. While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role. SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. Powered by JazzHR zwtspfch CM

We are looking for a highly-motivated Research Scientist/Engr-1 to join the growing and dynamic viral glycoprotein production team in the Veesler lab which supports vaccine and therapeutic development and structural studies of coronaviruses, paramyxoviruses, herpesviruses and other zoonotic pathogens. The position will involve competent participation in key projects, requiring analytical and decision-making skills in addition to technical skills and scientific knowledge of the field. **DUTIES AND RESPONSIBILITIES** Ongoing duties will include skillful management and support for projects and experiments, such as + Recombinant expression and purification of viral glycoproteins and other proteins in mammalian cells and E. coli (50%)with biochemical/biophysical characterization (using biolayer interferometry, ELISA, pull downs, electron microscopy) and serological evaluation of infection/vaccine-elicited antibodies using ELISA (25%). + In addition to the above extensive scientific project work, this position will involve: real-time reporting and analysis of data, providing input to key decisions on the direction of experiments, analyzing and reporting results (15%); participating in writing of scientific papers and manuscripts (10%). Most of these duties require a high level of specialized scientific education and skill, and play a key part in the overall success of the research projects. **MINIMUM REQUIREMENTS** Bachelor's Degree in Biochemistry, Biology or related field and one year of experience working in a biochemistry lab , OR Equivalent combination of education/experience. **ADDITIONAL REQUIREMENTS** + Hands-on experience with recombinant protein expression, prokaryotic and mammalian cell culture, secreted and cytoplasmic proteins, protein purification including common chromatographic methods (affinity, size exclusion, etc.), protein biophysical characterization, binding assays, stability assays, independent planning of timelines and experiments, and effectively communicating results and/or changes/progress with the other members of the team. + The position will involve recombinant expression and purification of viral glycoproteins in mammalian cells with biochemical/biophysical characterization (using biolayer interferometry, ELISA, pull downs, electron microscopy) and serological evaluation of infection/vaccine-elicited antibodies using ELISA. + The position requires a high level of organization, working independently and being a team-player, ensuring clear communication with other members of the team and real-time reporting of data. **DESIRED QUALIFICATIONS** Desire to set up high throughput glycoprotein production pipelines with multiple projects ongoing at a time; good analytical skills, ability to contribute to project decisions **Application Process** : A cover letter is required for this position and must be attached with your application for your application to be considered. **Compensation, Benefits and Position Details** **Pay Range Minimum:** $66,000.00 annual **Pay Range Maximum:** $74,400.00 annual **Other Compensation:** - **Benefits:** For information about benefits for this position, visit ****************************************************** **Shift:** First Shift (United States of America) **Temporary or Regular?** This is a regular position **FTE (Full-Time Equivalent):** 100.00% **Union/Bargaining Unit:** UAW Research **About the UW** Working at the University of Washington provides a unique opportunity to change lives - on our campuses, in our state and around the world. UW employees bring their boundless energy, creative problem-solving skills and dedication to building stronger minds and a healthier world. In return, they enjoy outstanding benefits, opportunities for professional growth and the chance to work in an environment known for its diversity, intellectual excitement, artistic pursuits and natural beauty. **Our Commitment** The University of Washington is committed to fostering an inclusive, respectful and welcoming community for all. As an equal opportunity employer, the University considers applicants for employment without regard to race, color, creed, religion, national origin, citizenship, sex, pregnancy, age, marital status, sexual orientation, gender identity or expression, genetic information, disability, or veteran status consistent with UW Executive Order No. 81 (*********************************************************************************************************************** . To request disability accommodation in the application process, contact the Disability Services Office at ************ or ********** . Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law (********************************************************* . University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.

The discovery immunology research team is seeking a highly motivated Principal Research Associate. This is a laboratory-based role where the successful candidate will contribute directly to research efforts by designing, executing, and analyzing experiments related to immune mechanisms, target validation, and therapeutic development. The position requires strong attention to detail and ability to multitask while working in a highly collaborative environment. Key Duties and Responsibilities: * Isolate, culture, and manipulate primary human immune cells and cell lines. * Design and execute experiments to interrogate immune cell phenotype and function, including cell-based multicolor flow cytometry and Incucyte assays. * Troubleshoot experiments and optimize protocols. * Collect, analyze, and interpret experimental data while maintaining accurate and detailed laboratory records. * Collaborate with scientists across discovery teams to achieve project goals. * Prepare data for internal reports and presentations for internal meetings. * Perform other duties as needed. Knowledge and Skills: * Hands-on tissue culture experience, including the isolation and maintenance of primary human immune cells and human cell lines. * Experience with nucleic acid techniques to quantify gene expression such as PCR, qPCR, and RNA sequencing. * Experience with a variety of cell-based immunology assays to interrogate immune cell phenotype and function including multicolor flow cytometry and Incucyte assays. * Experience measuring soluble analytes such as by ELISA, Luminex, or MSD. * Critical thinking and self-reliance to solve tasks independently or ask questions. * Strong organizational skills and attention to detail. * Willingness and ability to work in a highly collaborative environment. * Foundational knowledge of immunology and an eagerness to learn new techniques and skills. * Strong analytical skills and proficiency in the following software packages: Microsoft Office, GraphPad Prism, FlowJo and Methodical Mind Analysis Software. Education and Experience: * Master's degree (or equivalent degree) in biological sciences and 2+ years of relevant employment experience, or * Bachelor's Degree (or equivalent degree) in biological sciences and 5+ years of relevant employment experience Pay Range: $92,900 - $139,300 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

**The School of Medicine's** **_Division of Urology_** **has an outstanding opportunity for a** **_Temporary_** **Research Scientist/Engineer 1.** The Research Scientist/Engineer 1 (Payroll Title: Pro Staff Temp Position) will facilitate several ongoing research projects spanning basic science studies and clinical medicine, and interactions with several University Departments (Urology, Medicine, and Pathology) as well as collaborations with the Fred Hutchinson Cancer Center. This person will work under limited supervision to complete assigned tasks/projects demonstrating an ability to work independently. Overall direction will be supplied by the Biorepository Manager in routine meetings. The employee will be responsible for following these general guidelines and for making adjustments to these directions as the need arises. The employee will eventually be responsible for overseeing the day- to-day performance of work-study students who help complete routine duties and for assuring that they follow all safety regulations. The employee will also act as a Team Leader for our on-call rapid Tissue Acquisition Necropsy (TAN) program, coordinating and guiding a team of research scientists and physicians through tissue collections. This position is in the Department of Urology's Genitourinary Cancer Research Laboratory, within the biospecimen acquisition and processing group. This position involves acquiring peripheral blood, tissue, tissue biopsies, and urine specimens from the operating room, the urology clinic, and the morgue (a tissue acquisition) and processing and storing the specimens according to protocol. This position will supervise. undergraduate work-study students. Incumbents perform routine scientific work, collecting, processing, and applying standardized scientific procedures and techniques **_Duties and Responsibilities_** **Work closely with Department of Pathology personnel in the processing of specimens removed at surgery with the goal of tumor tissue acquisition: 10%** + Master techniques of tumor dissection following training by the genitourinary pathologist. + Utilize excellent eye-hand coordination in tissue dissection and pay exceptional attention to detailed protocols for tissue acquisition and processing. + Accommodate frequent changes in the operating room schedule, which will necessitate working a variable, on demand, schedule, and varying locations. + Lead an on-call rapid Tissue Acquisition Necropsy (TAN) team: + Rotate (every third week) as a leader of a TAN team. + Coordinate the arrival of the patient, physicians, and team to the morgue and oversee the collection. + Assist with the processing of samples, ensure all documentation is complete and accurate, and arrange for final transportation of the patient. + The TAN program necessitates that the applicant be in the laboratory within two hours of being paged. Each laboratory member participates in approximately 4-5 rapid autopsies per year. **Tissue Processing and Standard Histology: 10%** + There will be the need for the successful applicant to be sufficiently adept with techniques in histology (fixing, decalcification, sectioning, and staining of tissue), so as to make modifications to suit the particular research study with minimal guidance from the supervisor. **Blood and Urine Collection and Processing for clinical trials and research: 40%** + Utilize excellent attention to detail while logging human subjects consent forms, assigning lab IDs, and following clinical study protocols. + Use appropriate precautions while isolating serum, buffy coat, and/or plasma from blood specimens and processing urine samples. + Apply exceptional organizational skill and attention to detail when working with multiple protocols for sample acquisition and processing. + Contribute to the maintenance and organization of the Biospecimen freezers and arrange occasional shipping of specimens to Study Sites. **Collection and Documentation of Data: 20%** + Must be very attentive to detail and keep highly accurate records of specimens received and processed. + Demonstrate proficiency in data collection and input of data into databases. Complement these tasks with ability to run database queries to retrieve selected and sorted data. **Other Related Duties: 20%** + Interact in a collaborative manner with other team members to accomplish organizational goals and provide ideas for improved efficiency. Define and improve practices from experiences on small projects. + Learn new techniques as required for optimal job performance. Perform other duties as assigned. **_MINIMUM REQUIREMENTS_** + A Bachelor's degree in the basic biological sciences is required with an emphasis in one of the biology disciplines, + One year of relevant experience,OR equivalent combination of education/experience + Familiarity with spreadsheets and databases. **_DESIRABLE QUALIFICATIONS_** + Experience in the handling and processing of human tissues and blood is highly desired but not a requirement. + Experience working with clinical databases and/or EPIC systems is desirable. **_Conditions of Employment_** + Must be able to work under limited supervision to complete assigned tasks/projects and demonstrate an ability to work independently. + This position requires flexibility in the working hours, including extension into the evening when mandates by processing of specimens, and on occasion requires working outside of the standard workweek. **Compensation, Benefits and Position Details** **Pay Range Minimum:** $56,448.00 annual **Pay Range Maximum:** $56,448.00 annual **Other Compensation:** - **Benefits:** For information about benefits for this position, visit **************************************************************************************** **Shift:** First Shift (United States of America) **Temporary or Regular?** This is a temporary position **FTE (Full-Time Equivalent):** 100.00% **Union/Bargaining Unit:** Not Applicable **About the UW** Working at the University of Washington provides a unique opportunity to change lives - on our campuses, in our state and around the world. UW employees bring their boundless energy, creative problem-solving skills and dedication to building stronger minds and a healthier world. In return, they enjoy outstanding benefits, opportunities for professional growth and the chance to work in an environment known for its diversity, intellectual excitement, artistic pursuits and natural beauty. **Our Commitment** The University of Washington is committed to fostering an inclusive, respectful and welcoming community for all. As an equal opportunity employer, the University considers applicants for employment without regard to race, color, creed, religion, national origin, citizenship, sex, pregnancy, age, marital status, sexual orientation, gender identity or expression, genetic information, disability, or veteran status consistent with UW Executive Order No. 81 (*********************************************************************************************************************** . To request disability accommodation in the application process, contact the Disability Services Office at ************ or ********** . Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law (********************************************************* . University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to, among other things, race, religion, color, national origin, sexual orientation, gender identity, sex, age, protected veteran or disabled status, or genetic information.