TPO Research & Innovation Intern
Research Internship Job 49 miles from Hagerstown
Join our Thermoplastics Research & Development group as a TPO Research & Innovation Intern, where you'll work on projects related to our TPO Membrane product line. This role offers hands-on experience in both fundamental and applied research, providing an opportunity to contribute to product and process development.
Key Responsibilities:
* Conduct literature research on flexible TPO formulation and processing.
* Prepare samples for and perform physical and analytical testing.
* Analyze and interpret test results to support R&D projects.
* Present findings and conclusions to the team.
Summer Internship: Gene Therapy Research - Neuromuscular
Research Internship Job 49 miles from Hagerstown
Who We Are REGENXBIO is an exceptional place to work. You'll have the opportunity to collaborate with some of the best and the brightest people, touch amazing science, and be a part of extraordinary plans. Our core values: Trust, Accountability, Perseverance, and Innovation drive everything we do. We aim to bring these values to life every day with all that we do, and we believe that what we do matters - to patients, to their families, and to their communities.
The Opportunity
The Gene Therapy Research group is seeking an intern to support basic and translational gene therapy projects in the field of neuromuscular research. Specifically, the intern will probe expression of AAV-encoded transgenes following vector administration in genetic muscular dystrophy. The ideal candidate should have a strong interest in cutting edge therapies for genetic diseases. Curiosity, creativity, strong analytical skills and a desire to apply them to solve biological problems are welcome. This position will provide an immersive opportunity to experience aspects of a career in Research at a leading biotechnology company, including intra- and inter-departmental collaboration, designing and performing experiments, data analysis and presentation, all in a state-of-the-art facility.
What You'll Be DoingExtract DNA/RNA/protein extraction for use in downstream assays like PCR and Western blotting Process samples for fluorescent or brightfield microscopy and perform imaging experiments Analyze, interpret, and present data to audiences of diverse backgrounds Use cell culture models to complement animal studies Read relevant scientific literature, compile information and report findings Attend lab and project specific meetings
What We're Looking ForMinimum 2 years of college and currently enrolled in a Biology/Bioengineering/related major.Strong understanding of biology is required, with some understanding of anatomy and physiology preferred.Previous research experience in a biology, biochemistry, or molecular biology lab is strongly preferred. Experience in a cardiac or skeletal muscle biology/disease lab is highly desirable.Strong written and verbal communication skills.Familiarity with word processing, spreadsheet, and presentation software required. Experience using data analysis and/or graphing software is desirable.
$20 - $30 an hour
Why You Should Apply
By joining REGENXBIO, you will have the opportunity to be a part of a growing company and incredible team passionate about developing novel AAV gene therapy products to our patients. In addition, professional development is important to us. By joining our team, you'll have the opportunity to be exposed to challenging projects and development resources to help you grow personally and professionally.
Research Associate, Discovery
Research Internship Job 49 miles from Hagerstown
Arcellx (************************ is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx's mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible.
Primary Objective:
The Research Associate position is open to candidates who can demonstrate the ability to thrive in a modern and fast-paced biotechnology environment. A successful candidate will work with a cross-functional team responsible for the discovery and development of novel therapeutic proteins. The incumbent will be a result-oriented self-starter with a commitment to teamwork and reliability.
Main Accountabilities:
The main responsibilities will include but are not limited to:
Working with other scientists to design, generate and characterize recombinant proteins.
Execute selection and screening strategies used in discovery workflows.
Plan, execute, record and analyze experiments.
Preferred Qualifications:
Master's in the life sciences (e.g. Biology, Genetics, Biochemistry, Chemistry, Chemical Engineering), with a minimum of one year of work experience in a laboratory setting.
Proficient with molecular biology methods, including: primer design, PCR, gel electrophoresis, plasmid DNA preparation, cloning and sequence analysis.
Experience in with characterization of recombinant proteins, including but not limited to ELISA, MSD, SDS-PAGE, protein quantitation, etc..
Competencies:
Commitment to ethical scientific investigations and rigorous experimental methods.
Ability and desire to multitask and function in a fast-paced entrepreneurial environment.
Demonstrated ability to think critically and analyze and interpret data independently.
Sense of urgency in performance of duties.
Interpersonal skills that promote a collaborative and productive lab environment.
Effective and efficient written and oral communication skills.
Submit cover letter and resume
Without exception, applicants must submit both a cover letter and resume to be considered for these positions and must have experience in one of the fields listed above.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate
Research Internship Job 49 miles from Hagerstown
About us
CommunicateHealth is a growing health communication firm with a passion for health literacy and inclusive design. Our mission is simple: to improve lives by designing health information that's easy to understand and use. By making health communications that are clear, accessible, and inclusive, we give people what they need to make informed decisions about their health - and ultimately help advance health equity. Together, our mission-driven team designs inspiring solutions that transform the way people think about health.
About you
You're a mission-driven super organizer, with a knack for helping things run efficiently and effectively. You have research experience and are excited to support a variety of quantitative and qualitative health communication-related studies. You have a working knowledge of the end-to-end research process, strong communication skills, and enjoy developing new systems and processes. You like working both independently and collaboratively and display outstanding attention to detail.
What you'll do
Support research studies, including:
Conducting literature scans and environmental scans
Moderating study sessions, like interviews and usability tests
Helping to develop research briefs, study plans, reports, and research instruments like screeners, surveys, and moderator's guides
Oversee research logistics, including:
Communicating with recruitment vendors
Scheduling with research participants and managing the consent process
Facilitating research review and clearance processes, like Institutional Review Board (IRB) submissions
Tracking on the team's use of research tools and software
Requirements
At least 2 years of related work experience + a bachelor's degree in public health, communication, human-computer interaction, the social sciences, or other related field
Experience conducting research with diverse audiences
Experience conducting qualitative and quantitative research
At least 1 semester of formal quantitative research methods
Proficient in SPSS or other statistical analysis software
Excellent communication, planning, and organizational skills
CommunicateHealth is committed to workplace diversity and providing equal employment opportunities for all qualified applicants and employees. We proactively seek out diverse perspectives and apply them to strengthen our work and our employee experience.
As federal contractors, we are required to ask applicants to submit a voluntary demographics form. No personnel selections are made based on this information.
Benefits
We care
CommunicateHealth is committed to workplace diversity and providing equal employment opportunities for all qualified applicants and employees. We proactively seek out diverse perspectives and apply them to strengthen our work and our employee experience.
At CommunicateHealth, we acknowledge that our employees are the best and brightest, and we want to compensate you accordingly!
Excellent benefits
Open paid time off policy
401K with 3% company contribution
Comprehensive health, dental, and vision insurance plans (CH pays 85% for individuals and 80% for families and couples)
Up to 6 weeks paid parental leave (up to 6 additional weeks of unpaid leave) and flexible schedules for working parents
Life insurance base plan of $50,000
A healthy social and emotional work environment
Flexible schedules, including Summer Fridays
14 paid Holidays
Monthly all-staff Creative Time
Home office reimbursement
Standing desks
Co-working space reimbursement
Gym membership reimbursement (included with company-sponsored health insurance plan)
Personal and professional development and training
$1,500 of professional development funds annually
Tuition reimbursement
Student loan reimbursement
Company support for applying to and presenting at professional conferences
Individual coaching and mentoring
Company-wide and team-based trainings
Compensation range: $58,000 to $75,000
*This position requires physical presence in the United States. Candidates must reside in the United States to be eligible.
Research Associate, Bacteriology (#1860)
Research Internship Job 23 miles from Hagerstown
BACKGROUND
The National Biodefense Analysis and Countermeasures Center (NBACC) is a one-of-a-kind facility located on Fort Detrick in Frederick MD and is dedicated to defending the nation against biological threats. Its work supports DHS and National biodefense preparedness planning, response, emerging threat characterization and bioforensic analyses. It is the first national laboratory created by DHS in response to biodefense gaps identified following the Amerithrax attacks of 2001 and has been operated by the Battelle National Biodefense Institute (BNBI) since 2006. Since its inception, NBACC and its staff have filled critical shortfalls in our scientific knowledge of biological agents needed to protect the public and defend the Nation from biological threats, whether naturally occurring, accidental, or deliberate and provided federal law enforcement with scientific data to support the investigation and attribution of biocrimes and protection of the US bioeconomy.
NBACC includes two centers: the National Bioforensic Analysis Center (NBFAC), which conducts the technical analyses in support of federal law enforcement investigations, and the National Biological Threat Characterization Center (NBTCC), which conducts experiments and studies to obtain data required for a better understanding of biological vulnerabilities and hazards. Together these centers offer a unique national resource for understanding the risks posed by biological agents and emerging technologies to inform biodefense policy and response planning and the operational capability to support the investigation, prosecution, and prevention of biocrimes and bioterrorism.
PRIMARY FUNCTION
Utilizes standard methods for the identification of bacteria obtained from forensic evidence at the NBFAC in support of the FBI and other federal partners. Characterizes bacterial agents using phenotypic, biochemical and/or automated identification systems at Biosafety Levels 2, 3, and 4 under an ISO 17025 Quality Management System.
MINIMUM REQUIRED QUALIFICATIONS
Bachelor of Science (or equivalent) in a scientific discipline or engineering, and a minimum of 4 years of related experience.
Clinical laboratory experience and/or ASCP certification in Microbiology is highly desired.
Intermediate scientific proficiency in laboratory functions. Possesses the ability to identify issues with laboratory protocols, procedures, and experimental plans.
Proficiency and clarity of oral and written communications are essential.
Exemplary organizational skills with a proven track record of working effectively both independently and as a team player.
Knowledge or experience with biocontainment facilities and procedures, laboratory safety, biosurety, and decontamination is desirable.
Skills and experience to support laboratory activities and work in accordance with NBACC's management system (e.g., ISO).
Must be a citizen of the United States, able to obtain and maintain an interim secret clearance leading to a top secret clearance, suitability for DHS, and a favorable adjudication of the Department of Justice (DoJ) for select agent access.
Participation in the Immunization Program, Medical Surveillance Program and enrollment in the Personnel Reliability Program (PRP) is required.
May be required to participate in NBACC's alternative work and/or on-call schedule, dependent upon business needs.
PRIMARY RESPONSIBILITIES
Conducts bioforensic casework at BSL-2, BSL-3 and BSL-4 by performing standard bacteriological analyses such as gram staining, antibiotic resistance testing, phenotypic/biochemical testing and automated bacterial identification (Vitek 2 and BIOLOG). Participates in Laboratory Response Network (LRN) analyses on environmental and clinical (if required) samples.
Accurately documents and maintains results, equipment, and reagents in a computerized Laboratory Information System (LIMS) and interprets data for the preparation of analytical reports.
Participates in the research and development of new methods and technologies for bacterial characterization.
Performs maintenance and characterization of the Bioforensic Repository Collection including shipment of materials.
Ability to cross-train with other NBFAC teams.
Possesses the ability to work on multiple science tasks simultaneously, while performing assignments outside of area of expertise.
Exercises judgment within generally defined practices and policies in selecting methods and techniques for obtaining solutions.
Follows established procedures on routine work, requires instruction only on new assignments, and is self-sufficient in monitoring and reporting on quality and compliance.
Participates in the testing and evaluation of new technologies and protocols including writing and updating NBACC Standard Operating Procedures (SOPs), work instructions and forms to improve NBACC's ability to serve its customers.
Identifies departures from the Quality Management System (QMS) and initiates actions to investigate and prevent such occurrences.
With minimal supervision, operates, maintains, and characterizes the performance of equipment ensuring the reagents and supplies are maintained and used properly.
Serves as a member of a team in developing, validating and maintaining methods for identifying and characterizing biological threat agents.
Must be a team player, communicate clearly, be open to hearing ideas and suggestions from others, diffuse situations, and exercise empathy and patience with colleagues.
Must have the ability to multi-task, maintain composure under pressure, and utilize effective time management skills to prioritize tasks.
Must be a self-starter driven by an eagerness to succeed, maintain flexibility, adapt to change in a productive and positive manner, learn new concepts, and utilize critical thinking to resolve complex problems.
Maintains appropriate records.
Performs other duties as assigned/authorized.
BNBI prohibits discrimination and employs and advances individuals without regard to race, color, religion, age, sex, national origin, disability or veteran status.
Research Associate
Research Internship Job 49 miles from Hagerstown
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).
Axle is seeking
Research Associates
to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.
We are seeking Research Associates to support various program areas for clients such as the NIH. The interns will collaborate with their manager, mentor, and teams to actively contribute to project execution and decision-making processes. This role offers invaluable hands-on experience and exposure to the work life at NIH.
This is a 12-week paid internship program. There will be two cohorts: Summer and Fall. Each cohort will accept up to 20 interns. This position is hybrid and interns will be expected to report to Axle's HQ three days a week.
PLEASE NOTE: Axle will not be reviewing applications until April 2024.
Program Areas:
Software Development for AI
Data Science AI/ML/LLMs
Automation/IoT/Robotics
DevSecOps and MLOps
Cyber Security for AI
Generative AI
The ideal candidate:
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
div id="apply-description"div class="description"pspanspanstrong Research Associate, Next Gen Sequencing/strong/span/span/p pspan My client is expanding and seeks a Research Associate to join their team./span/p p /p pspanstrong Key Responsibilities:/strong /span/p
divspan1.span /span Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device./span/div
divspan2.span /span Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated./span/div
divspan3.span /span Prepare and present technical data and reports./span/div
divspan4.span /span Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly./span/div
div /div
pspan /span/p
pspanstrong Essential Qualifications:/strong/span/p
ul
lispan BS/MS in molecular biology or similar./span/li
lispan Excellent analytical and problem-solving skills./span/li
lispan Strong communication and collaboration abilities to work effectively in interdisciplinary teams./span/li
/ul
pspan /span/p
pspanstrong Essential Experience:/strong/span/p
ul
lispan1-5 years of next generation sequencing /span/li
lispan Familiarity and experience working with Oxford Nanopore methods./span/li
lispan Data analysis and presentation./span/li
/ul
divspan /span/div
pspanstrong Additional notes:/strong/span/p
pspan--This is a Research Associate or Sr Research Associate role./span/p
pspan--Compensation includes base salary + discretionary bonus + exceptional benefits package./span/p
pspan--Relocation allowance is available./span/p
p /p/div/div
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate
Research Internship Job 49 miles from Hagerstown
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).
Axle is seeking
Research Associates
to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.
We are seeking Research Associates to support various program areas for clients such as the NIH. The interns will collaborate with their manager, mentor, and teams to actively contribute to project execution and decision-making processes. This role offers invaluable hands-on experience and exposure to the work life at NIH.
This is a 12-week paid internship program. There will be two cohorts: Summer and Fall. Each cohort will accept up to 20 interns. This position is hybrid and interns will be expected to report to Axle's HQ three days a week.
PLEASE NOTE: Axle will not be reviewing applications until April 2024.
Program Areas:
Software Development for AI
Data Science AI/ML/LLMs
Automation/IoT/Robotics
DevSecOps and MLOps
Cyber Security for AI
Generative AI
The ideal candidate:
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate, Next Gen Sequencing
Research Internship Job 49 miles from Hagerstown
My client is expanding and seeks a Research Associate to join their team.
Key Responsibilities:
1. Contribute to the NGS platform, receiving and processing samples for sequencing using Oxford Nanopore device. 2. Optimize the NGS pipeline from nucleic acid extraction to sequence read processing to ensure that high quality data is generated. 3. Prepare and present technical data and reports. 4. Maintain an up-to-date lab notebook, actively participate in meetings, prepare presentations, and communicate to leadership team regularly.
Essential Qualifications:
BS/MS in molecular biology or similar.
Excellent analytical and problem-solving skills.
Strong communication and collaboration abilities to work effectively in interdisciplinary teams.
Essential Experience:
1-5 years of next generation sequencing
Familiarity and experience working with Oxford Nanopore methods.
Data analysis and presentation.
Additional notes:
--This is a Research Associate or Sr Research Associate role.
--Compensation includes base salary + discretionary bonus + exceptional benefits package.
--Relocation allowance is available.
Research Associate - Biology - I
Research Internship Job 44 miles from Hagerstown
Kite, a Gilead Company, is a biopharmaceutical company focused on the development and commercialization of Client cancer immunotherapy products designed to harness the power of a patients own immune system to selectively target and kill cancer cells. Our core technology involves the genetic engineering of T cells, or white blood cells, to express either chimeric antigen receptors (CARs) or T cell receptors (TCRs) for the treatment of advanced solid and hematological malignancies. We are on a rapid growth trajectory and have a highly energized and accomplished team driving to new frontiers of care for cancer patients.
Kite is seeking a highly motivated individual with cell culture experience to work on innovative T cell therapy for cancer treatment at a new research and clinical production facility located in Gaithersburg, Maryland. This facility will focus on the new challenging field of fully personalized T cell neoantigen reactive therapy for solid tumors using individual patient neoantigen TCRs. As a Research Associate / Associate Engineer in Process Development, you will provide process development support for New INDs, technology transfers, process validations and GMP manufacturing for Kites neoantigen TCR therapy product. Additionally, you will draft and review protocols, production procedures, and process development reports. You will work with the Viral Vector Process Development team to design and scale-out cell therapy processes, manage equipment qualification and support process validation, as well as draft documentation for regulatory filings to advance Kites product portfolio.
Key responsibilities:
Hands on execute and collaborate on process design laboratory studies to support process development, optimization and characterization and essential viral vector process improvements.
Perform hands on work in a cell culture lab and process training for GMP clinical production.
Participate and influence a cross-functional development team to advance CMC activities
Perform process analysis and trend process performance
Develop manufacturing processes for cell therapy products
Design and execute process development studies to develop a thorough understanding of operating and performance parameters
Perform statistical analysis including design of experiments (DOEs) as appropriate
Write and review technical documentation from writing technical SOPs, draft manufacturing batch records, technical reports and summary reports.
Other duties as assigned
Qualifications:
Degree in Biology, biochemistry or biotechnology degree or related discipline with 1-2 years of pharmaceutical manufacturing, technology transfer & process development experience required
Demonstrated cell culture and aseptic processing experience is required including basic cell culture lab techniques such as cell passaging, cryopreservation, formulation of media, aseptic technique using a BSC, cell counting, and managing reagents.
Practical knowledge of cGMP manufacturing and regulatory regulations and requirements for pharmaceuticals and devices.
Practical demonstration of hands on process development including use of statistical design of experiments is required. Experience with bioreactors is desired.
Mastery of scientific and engineering principles
Skills:
Demonstrated knowledge of pharmaceutical manufacturing of biotechnology products, aseptic processing, cell therapy products and process development
Ability to think critically, and demonstrated troubleshooting and problem solving skills
Excellent interpersonal, verbal and written communication skills are required.
Ability to function efficiently and independently in a changing environment
Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description
Well-developed computer skills
High energy level and a positive outlook coupled with the requisite can do attitude and a willingness to do what it takes to achieve personal and organizational goals and overcome obstacles
Comfortable in a fast-paced environment with minimal direction and able to adjust workload based upon changing priorities
Ability to work and collaborate in cross functional teams, research, development, manufacturing in a fast pace, dynamic team setting
Experience:
Must have 1-2 years of pharmaceutical process development experience
Pharmaceutical products GMP manufacturing experience is desired
Cell culture or aseptic processing experience is a plus
Previous experience with cell therapy products is a plus
Understands and employs principles and concepts of Lean Six Sigma or design of experiments to improve process capability is a plus
Experience in statistical analysis using JMP or Minitab
Proven track record of working within cross functional teams
Knowledge of data management tools and statistical process controls
Laboratory Research Technician III
Research Internship Job 23 miles from Hagerstown
Zachary Piper Solutions is seeking a Laboratory Research Technician III to join a Federal Program located in Frederick, MD. The Laboratory Research Technician will support the Department of Defense by conducting tests, collecting data, and analyzing scientific studies.
Responsibilities of the Laboratory Research Technician III include:
* Support small and large animal studies in BSL-2, BSL-3, and BSL-4 laboratories.
* Perform inoculations with viruses, vaccines, or testing materials.
* Collect tissues and blood samples for processing.
* Conduct in vitro testing of candidate vaccines and therapeutic compounds.
* Prepare cell culture media and other study supplies.
* Perform immunological procedures (ELISA, Western Blot) and various assays (cell culture, plaque assays, PRNT, PCR).
* Manage lab supplies and assist with Equipment Inventory Management.
Qualifications for the Laboratory Research Technician III include:
* Bachelor's degree in Molecular Biology, Microbiology, Biochemistry, Immunology, Biology, or a related field and 1+ years lab experience
* Skilled in Molecular Biology Assays (ELISA, Western Blot, Plaque Assays, PRNT assays, PCR)
* Experience in handling large and small animals, including NHPs and rodents
* Proficient in performing animal inoculations, blood and tissue collection, and sample processing
* Excellent communication, organizational, and multitasking skills
* Prior experience in BSL-2, BSL-3, and BSL-4 biocontainment labs preferred
* Must have an Active Secret Clearance
Compensation for the Laboratory Research Technician III includes:
* Salary Range: $60,000 - $70,000 depending on experience
* Comprehensive Benefits: Cigna Medical, Dental, Vision, 401K, PTO, Sick Leave if required by law, and Holidays
This job opens for applications on 3/19/2025. Applications for this job will be accepted for at least 30 days from the posting date.
Keywords:
Lab Tech, Lab Research Tech, Secret clearance, BSL-2, BSL-3, BSL-4, BPRP status, Laboratory experiments, Cell culture, Plaque assays, PCR, Animal procedures, Data analysis, Laboratory equipment, ELISA, Western Blot, NHPs, Rodents, Immunological procedures, Lab management, Molecular Biology, Microbiology, Biochemistry, Immunology, Bachelor's degree, Lab experience, GFEBs ordering system, Communication skills, Organizational skills, Multi-tasking, Interpersonal skills, Security investigation, Military-friendly employer, Veterans, Scientific Research Assistant, Research Laboratory Technician, Research Technical Specialist, Frederick, Frederick MD, Maryland, Secret, Active Clearance, Cleared, Laboratory Manager, Research Technician, Laboratory Analyst, Laboratory Assistant, Laboratory Supervisor, Quality Control Technician, Laboratory Specialist, Quality Control Laboratory Technician, Research and Development Technician, Medical Equipment Technician, Phlebotomist, Anesthesia Technician, Medical Technologist, Histology Technician, Pathologist Assistant, Nuclear Medicine Technologist, Cytotechnologist, Chemist, Microbiologist, Analytical Chemist
#LI-KG1
#LI-ONSITE
#PANDOLOGIC
Research Technician, Extraction and Staging Laboratory, CGR
Research Internship Job 49 miles from Hagerstown
Employee Type: nonexempt full-time Division: Clinical Research Program Facility: Rockville: 9615 MedCtrDr
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world's most comprehensive cancer epidemiology research group. CGR is located at the NCI-Shady Grove campus in Gaithersburg, MD and operated by Leidos Biomedical Research, Inc. We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG. Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG's intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. This includes the design and analysis of high throughput studies using various types of “-omics” technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome.
KEY ROLES/RESPONSIBILITIES
The Cancer Genomics Research (CGR) laboratory is a fast-paced, high throughput organization that supports histology, molecular and digital pathology, nucleic acid extraction, sample staging, genotyping, sequencing, and analysis for genetic and epidemiologic studies for the investigators within DCEG. We are recruiting for a Research Technician position within CGR's Extraction and Staging Laboratory that supports sample extraction, quantitation, and normalization of the extracted nucleic acid for all sequencing and genotyping efforts. The Research Technician position will focus on sample extractions from multiple types of human biospecimens, quality and quantity assessment of the extracted nucleic acids, and custom aliquoting of biospecimens to support internal and external assay requirements. The successful candidate will work seamlessly within the extraction, staging and aliquoting teams and will have responsibility for the day-to day execution of laboratory processes and applications including:
Participate in all facets of the sample extraction and QC pipeline, including nucleic acid extraction from various sample types (BSL-1 and BSL-2), sample handling and quantification using multiple automation platforms and laboratory equipment
Use of automated liquid handling robotics and additional methods in BSL-2+ controlled laboratory space to support biospecimen aliquoting tasks for both in house and outsourced assays
Organization of samples, including sorting by tube type and relabeling as needed for automation workflows
Support for sample inventory efforts, including freezer consolidation activities and preparation of samples for return to external collaborators and/or NCI Central Repository
Use of LIMS for tracking all aspects of sample management
Responsible for performing, documenting, and reporting results and deviations for a variety of procedures and assays in the laboratory, governed by SOPs
React to any non-conformances or opportunities for improvement, by taking appropriate corrective actions in consultation with management, development team and other relevant staff members
Ensure proper documentation of all laboratory processes performed in the laboratory and maintain equipment records
Perform routine maintenance of laboratory equipment and maintain a clean work area
Practice safe work habits, including complying with all safety, health and environmental rules and regulations
Other duties as assigned and available
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
Possession of a bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
In addition to education requirements, a minimum of 0-2 years of related molecular biology experience
Knowledge of DNA and RNA extraction, quality, and quantitative assessment of nucleic acid from a variety of biospecimen types
Strong written and oral communication skills
Computer literacy (Microsoft Office products, general computer proficiency)
Ability to apply routine mathematics to laboratory calculations
Ability to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
Experience in nucleic acid extractions from human biospecimens and quantitation of DNA and RNA
Familiarity with liquid handling robotics
Experience with data analysis and visualization tools such as Excel, Spotfire, Tableau
Demonstrated attention to detail
Ability to prioritize and multi-task
JOB HAZARDS
This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.
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Summer Internship: Gene Therapy Research - Ophthalmology Research
Research Internship Job 49 miles from Hagerstown
Who We Are REGENXBIO is an exceptional place to work. You'll have the opportunity to collaborate with some of the best and the brightest people, touch amazing science, and be a part of extraordinary plans. Our core values: Trust, Accountability, Perseverance, and Innovation drive everything we do. We aim to bring these values to life every day with all that we do, and we believe that what we do matters - to patients, to their families, and to their communities.
The Opportunity
The Research & Early Development department has an opportunity for a talented and motivated undergraduate or graduate student interested in pursing a career in gene therapy for ocular diseases. The intern will gain experience in developing assays and performing in vitro laboratory experiments that contribute to the selection of lead gene therapy candidates for treating human ocular disease indications.
What You'll Be DoingPerform in vitro and cell-based assays, ELISA & others Maintain cell lines in culture Perform molecular techniques such as tissue homogenization, DNA/RNA/protein extraction, qPCR, dd PCR, western blot, immunohistochemistry, and microscopy Analyze data, prepare study reports and keep organized experimental records Assist with other activities as assigned REGENXBIO employees must embody our core values by working collaboratively, building strong relationships, and using clear communication to meet shared objectives.
What We're Looking ForCurrently enrolled in an undergraduate or graduate school program or have graduated within 6 months of the internship start date Must be pursuing a degree in Biology, Neuroscience, Life Science, Vision Science, Genetics, Biochemistry, Biomedical Engineering, Immunology, or related fields Must have basic laboratory experience
$20 - $30 an hour
Why You Should Apply
By joining REGENXBIO, you will have the opportunity to be a part of a growing company and incredible team passionate about developing novel AAV gene therapy products to our patients. In addition, professional development is important to us. By joining our team, you'll have the opportunity to be exposed to challenging projects and development resources to help you grow personally and professionally.