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Top 50 Research Investigator Skills

Below we've compiled a list of the most important skills for a Research Investigator. We ranked the top skills based on the percentage of Research Investigator resumes they appeared on. For example, 8.5% of Research Investigator resumes contained Analytical Methods as a skill. Let's find out what skills a Research Investigator actually needs in order to be successful in the workplace.

These are the most important skills for a Research Investigator:

1. Analytical Methods

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high Demand
Here's how Analytical Methods is used in Research Investigator jobs:
  • Developed and experimentally validated analytical methods to estimate performance of different molecules in optically pumped far infrared lasers.
  • Authored, reviewed and edited scientific reports, operating procedures and analytical methods.
  • Managed the development of analytical methods and process validation for both compounds.
  • Developed and validated BET surface area and particle size analytical methods.
  • Developed and validated analytical methods for multiple analyses per ICH guidelines.
  • Performed technology transfer of multiple analytical methods to the manufacturing site.
  • Develop and GMP-validate solid state analytical methods for pharmaceuticals.
  • Validated and implemented quantitative analytical methods for the determination of biomarkers in biological matrices.

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2. Cell Culture

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3. Lab Equipment

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Here's how Lab Equipment is used in Research Investigator jobs:
  • Evaluated new lab equipment and procedures in order to streamline the processes and increase the turnaround time of in-process samples.
  • Evaluated new lab equipment and procedures.

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4. Drug Discovery

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Here's how Drug Discovery is used in Research Investigator jobs:
  • Designed and synthesized novel and biologically active compounds for drug discovery programs (inflammation and oncology).
  • Carried out antiviral drug discovery studies with hepatitis B virus, for publication and regulatory submission.
  • Led several drug discovery projects in the gene-to-target and lead-to-candidate matrix.
  • Implement laboratory automation for high-throughput drug discovery and analysis.
  • Participated in the design, integration, and deployment of software related to drug discovery.
  • Led HBV drug discovery effort targeting hepatitis B virus (HBV) replication inhibitors.
  • Serve as a Drug Safety Evaluation Representative for drug discovery and development teams.
  • Screened compounds by different assays for the drug discovery.
  • Evaluated application of fusion protein in the drug discovery.
  • Provided bioanalytical support for drug metabolism studies and drug discovery projects.
  • Provided general chemoinformatic support for drug discovery projects in the Active to Lead (A2L) stage.
  • Project leader for two lipid kinases and one ion channel drug discovery program.
  • Developed assays in-house for studying gastrointestinal motility - Delivered data packages for drug discovery programs targeting gastrointestinal motility and visceral pain
  • Developed tubulin polymerization assay in house to examine tubulin agents for the drug discovery.
  • Set up Biologics group in charge of small/medium scale protein production supporting various drug discovery programs within the Musculoskeletal Department.

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6 Drug Discovery Jobs

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5. Research Projects

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Here's how Research Projects is used in Research Investigator jobs:
  • Supervised research projects, coordinated data and ensured university regulatory compliance.
  • Assisted in conducting research projects in an unsupervised working environment.
  • Conduct independent research projects with monthly oversight by the head of the laboratory.
  • Develop and implement new research projects.
  • Support in other research projects and educational programs including the following tasks: administrative and financial managing.
  • Applied microscopy techniques while investigating inhibitory interneuron transmissions relating to Schizophrenia Quantified protein distribution and supported data gatherings for ongoing research projects

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4 Research Projects Jobs

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6. Protein

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Here's how Protein is used in Research Investigator jobs:
  • Established definitive protein binding services in partnership with a major pharmaceutical company.
  • Developed or directed improvements in protein purification protocols and characterization assays.
  • Introduced new technology important for improving protein stability.
  • Established protocols for protein re-folding.
  • Digested purified proteins for use in the cell assay using a method to mimic human gut digestion.
  • Established the role of the Acm1 signal protein within the Anaphase-Promoting Complex.
  • Directed the purification and characterization of recombinant protein targets within the Molecular Sciences department.
  • Apply orthogonal higher order structure methodologies for protein, glycoconjugates and carbohydrates interactions.
  • Determined purified protein concentrations using the bicinchoninic acid assay.
  • Provided support in analyzing protein pegylation substances.
  • Managed a Protein Biochemistry Group consisting of one Ph D. and three associate scientists.
  • Purified and characterized protein targets (e.g.
  • Coordinated protein purification efforts with scientists in enzymology, X-ray crystallography, and bio-analytical chemistry.
  • Study of antihyperglycemic effect of a novel protein from plant in alloxan induced diabetes in mice 5.
  • Used radio-ligand binding, photoaffinity labeling, mass spectrometry and neurotransmitter uptake assays to identify proteins interacting with the drug compounds.
  • Analyzed protein-protein and protein-ligand interactions using techniques such as: microcalorimetry, circular dichroism, and equilibrium binding assays.
  • Established CE-LIF method to determine protein glycosylation (monosaccharide and N-glycan composition).
  • Assessed drug molecules for bioactivation potential through nucleophile trapping studies and protein covalent binding.
  • Developed novel preclinical potency assays to measure activity of human alpha-fetoprotein, MM-093 under clinical and preclinical development.
  • Design and conjugation of various ligands including peptides proteins and folic acid, for the targeting delivery of gold nanoshell.

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2 Protein Jobs

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7. Clinical Trials

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Here's how Clinical Trials is used in Research Investigator jobs:
  • Acted as the representative of the discovery organization to monitor clinical trials of the lead compound in sleep therapy.
  • Developed Point of Care assays for clinical trials and First in Human studies
  • Conducted Phase 1 PK clinical trials.
  • Coordinate clinical trials involving respective patients who qualify for participation, while acting as the Subinvestigator.
  • Conducted numerous clinical trials to determined disease pathogenesis and progression.
  • Develop the process used for preparation of 2 kg drug substance under cGMP to support Phase I clinical trials.
  • Develop biomarker assays to support clinical trials.
  • Worked with team members at Genentech Corp. to ensure a transition from Phase II to Phase IIIclinical trials.
  • Conducted preformulation studies, and developed formulations for clinical trials for NCEs.

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8. Assay Development

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1 Assay Development Jobs

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9. Biology

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Here's how Biology is used in Research Investigator jobs:
  • Manage Research Associates in Cell Biology and Pharmacology Departments.
  • Managed the Quality Control microbiology laboratory.
  • Created, Managed and supervised research laboratories in the Transplantation Biology Program in the Clinical Division.
  • Directed two job rotations of senior biochemists through the molecular biology group.
  • Used extensive cell and molecular biology techniques.
  • Volunteered in the Department of Developmental Neurobiology in the Behavioral Pharmacology Lab.
  • Consulted on sample management, molecular biology, therapeutic, and ADME/Tox departments with their automation and screening projects.
  • Provide primary backup for the Cell Biology and Flow Cytometry Core Facility (CellCore) Manager s responsibilities.
  • Invited speaker at Gordon Research Conferences on Glycolipid & Sphingolipid Biology.
  • Collaborate with Purdue molecular food and microbiology Bunia Lab, training and build up data base for BARDOT machine.
  • Leveraged computational biology, bioinformatics and pathway analysis to assess hepatotoxicity potential for compounds in an in vitro targeted gene assay.

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12 Biology Jobs

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10. Data Analysis

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Here's how Data Analysis is used in Research Investigator jobs:
  • Provide direction and expertise as needed with data analysis and trouble-shooting.
  • Summarized data analysis and conclusions; generated reports and made recommendations.
  • Performed data analysis and assay troubleshooting.
  • Perform small animal nuclear imaging (T2 and T1 MRI) and data analysis.
  • Develop programs (C/C++) to support the data analysis pipeline
  • Developed methods for dose-response surface fitting, and applied them to data analysis of tertiary systems (i.e.

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2 Data Analysis Jobs

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11. PCR

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Here's how PCR is used in Research Investigator jobs:
  • Conducted antibody production, characterization and analysis for GPCR receptor expression.
  • Created robotic friendly paradigm for PCR product characterization and archiving.
  • Developed assays for enzyme and GPCR targets using molecular, cellular, biochemical, and pharmacological techniques.
  • Supported several GPCR targets by screening compounds in calcium mobilization assays.
  • Performed independent DNA work including isolation, purification, PCR replication, and verification of samples using agarose gels.
  • Involved in the synthesis of numerous reported bio-active ligands for internal GPCR focused library screening collection.
  • Generated multiple stable cell lines expressing the desired levels of the GPCRs and used for HTS.
  • Isolated RNA and performed qPCR on panels of specific disease-related transcripts.
  • Performed a wide range of technics including protein purification, Western Blot, qPCR, cloning.

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12. Internal Medicine

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Here's how Internal Medicine is used in Research Investigator jobs:
  • Recruited and screened individuals from the Internal Medicine Outpatient Clinic at the University of Illinois Hospital.

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1 Internal Medicine Jobs

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13. Data Collection

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Here's how Data Collection is used in Research Investigator jobs:
  • Performed literature search, data collection, analysis of results, created written proposals, memorandums and conducted meetings.
  • Included extensive research on the topic, experimental design, data collection, and analysis using SPSS.
  • Assay design, cell and tissue analysis, data collection and validation.
  • Assisted in the development of survey instrument and data collection procedures.
  • Supervised undergraduate research training on-site in Puerto Rico, completing field data collection.

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14. Research Study

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Here's how Research Study is used in Research Investigator jobs:
  • Provided documentation of all individuals who were evaluated for participation in the research study.
  • Recruited and screened participants for the Motivational Interviewing (MI) & Problem Solving Tools (PST) research study.
  • Created the study, coded statistics, wrote and ran 30 trails for the research study
  • Investigated and coordinated research study on success measures in the social and business sectors.
  • Designed a research study with my mentor Dr. Squier, Professor of Oral Pathology at the University of Iowa Dental School.
  • research presentation series to educate clinical residents and fellows on research study design and methodologies (2002- current).
  • Recruited participants for the Impact of Integrated Doula Services research study.
  • Coordinated research study involving the Amgen sponsored drug Epogen.

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15. Hplc

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Here's how Hplc is used in Research Investigator jobs:
  • Worked with a team to develop a HPLC/UV method for analysis of a drug product and its impurities.
  • Collaborated in the development of a fluorescence assay for detection of selected steroids in human urine by HPLC.
  • Developed HPLC method for product quality control.
  • Established HPLC assays from initial method development through final validation to aid in formulation development and preclinical profiling.
  • Purified libraries of compounds using preparative HPLC.
  • Analyzed oxidation, deamidation, aggregation and other product variants with RP-HPLC, IEC, SEC as well as peptide mapping.
  • Developed HPLC/DAD/MSn (trap), HPLC/ MSn, and GC/MSD Methods.
  • Provide expert analytical solution to support purification and chiral resolution of stereoisomers using semi-prepHPLC and SFC.

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16. IRB

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Here's how IRB is used in Research Investigator jobs:
  • Received IRB approval from both the academic institution and the hospital affiliated with existing archival data.
  • Drafted research proposals and grant applications, and underwent an IRB application and review process.
  • Prepared research proposals, IRB applications, written reports, manuscripts, and conference presentations.
  • Prepare Institutional Review Board (IRB) application for submission.
  • Prepared, submit and obtained IRB ethical approval Collecting noninvasive data via transthoracic Echocardiogram Start initial manuscript draft

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17. FDA

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Here's how FDA is used in Research Investigator jobs:
  • Prepared laboratory for FDA inspection.
  • Execute nationwide telephone interviews with doctors, pharmacists and nurses regarding new pharmaceuticals or new FDA indications.
  • Submitted reports to FDA for review and comment once reports were completed.
  • Obtained concurrence from FDA on project proposals for new drug clearances.
  • Contributed to the FDA filling for a marketed pharmaceutical by profiling toxicity-related genes' expression in animal livers with microarray.
  • Prepared and issued the CMC section of the FDA/EMEA dossier for IND for one of these oligonucleotides.
  • Validate realtime PCR assays detecting bacterial pathogens based on FDA and AOAC regulations.
  • Presented echocardiography program for ABT-869 to the FDA and received approval.
  • Contract Assignment: Pharmaceutical Research Investigation Perform tests on medicated subjects of clinical investigation Evaluate and research of pharmaceutical drugs for FDA

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18. DNA

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Here's how DNA is used in Research Investigator jobs:
  • Prepared and formulated antibody-DNA conjugates for target delivery of antigen to immune cells.
  • Conducted enzymatic assays with isolated DNA samples and proteins.
  • Explored mechanistic rationale to target DNA-PK.
  • Managed laboratory to produce and analyze DNA microarrays.
  • Designed and developed protocols for YAC DNA screening and purification to produce a Huntington's disease calpain resistant transgenic mouse model.
  • Explored the biomarker potential of DNA-PK.
  • Assembled mononucleosomes from purified DNA samples.
  • Conducted in vitro and in vivo studies to validate DNA-PK as an effective therapeutic target in aggressive prostate cancer.
  • Conducted research in Drosophila development and genetics by performing deficiency screens of mutant flies Managed DNA and tissue samples.
  • Developed cell tissue culture techniques that enhanced cDNA transfection procedures in this lab.
  • Clone DNA from cDNA library, genomic DNA and other resources.
  • Characterized cDNA library from trabecular meshwork in greater details.
  • Constructed cDNA libraries from various eye tissues including trabecular meshwork, cornea, iris, retina, choroid, etc.

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19. R

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Here's how R is used in Research Investigator jobs:
  • Developed number of stability-indicating HPLC assay/impurity methods to support developments of new drug products in different dosage forms.
  • Developed and maintained internal/external collaborations for evaluation and validation of drug targets for Type II diabetes.
  • Communicated research vision, and provided learning and career development opportunities within group and department.
  • Maintained and utilized multiple MS platforms for experiments involving collaborative projects among multiple laboratories.
  • Collaborated with four sites for method co-validations/method transfers and stability studies.
  • Offered learning and career development opportunities within group/department.
  • Delivered lectures at national and international meetings.
  • Prepared external collaboration agreements with legal department.
  • Performed and guided dissolution method development and validation for number of solid dosage forms, including tier II dissolution method.
  • Attended scientific meetings and reported relevant scientific results within team and department as well as remained abreast of current literature.
  • Provided technical and compliance advice to manufacture site, contract labs, and internal analysts.
  • Completed multiple method transfers for a number of projects at different stages/studies.
  • Attended conferences and discussed research results from 15 different projects.
  • Invited to give 4 seminars on work developed.
  • Authored number of analytical methods, validation protocols/reports, and study reports.
  • Nominated compounds & biologics (AGN X, AGN XX & AGN XXX) for clinical development from discovery research.
  • Designed and executed method validations at different stages, from tox studies, Phase I to Phase III.
  • Developed multiple MS based research projects for the quantification of protein turnover and PTMs.
  • Published more than 22 peer reviewed articles in basic and applied research.
  • Identify and quantify changes in chemokines secreted by human fibroblast cells which regulate the senescence phenotype via a SILAC MS method.

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20. Background Checks

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Here's how Background Checks is used in Research Investigator jobs:
  • Conducted personal-employee background checks to determine any possible criminal, civil and/or fraud violations.
  • Communicated with numerous courts around the nation while conducting background checks.
  • Assist a local private investigator with requested background checks.
  • Conducted reference and background checks on all job applicants.
  • Conduct appropriate research for pre-employment screening and background checks.
  • Performed background checks and conducted mediation sessions Initiated and completed extensive surveillance Coordinated research efforts for clients

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2 Background Checks Jobs

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21. Drug Candidates

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Here's how Drug Candidates is used in Research Investigator jobs:
  • Managed an extramural research program on Immunology and Oncology Drug candidates- over 40 academic investigators.
  • Demonstrated production of drug metabolites matching those from human liver cells, accelerating screening of drug candidates and lowering costs.
  • Served as member of cross-functional integrated development teams (IDT) responsible for coordinating/executing CMC activities for drug candidates.
  • Designed and executed studies in preclinical models to evaluate potential drug candidates for efficacy and to understand their mechanisms of action.

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2 Drug Candidates Jobs

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22. Spss

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Here's how Spss is used in Research Investigator jobs:
  • Utilized SPSS to analyze respondents' results to develop a comprehensive menu for the convention stand.
  • Analyzed all gathered data using SPSS and qualitative coding procedures over twenty months.
  • Conducted all analyses using SPSS.
  • Interviewed participants for study in jail setting Performed data entry into SPSS Supervisor: Lenore Walker, Ed.D., ABPP

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23. NIH

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Here's how NIH is used in Research Investigator jobs:
  • Noted and provided feedback to supervisors to improve study design for NIH grant proposal.
  • Research grants provided by NIH, CEED and Merck/AAAS.
  • Awarded a NIH funded training grant from the Center for Organogenesis at the University of Michigan.

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24. GMP

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Here's how GMP is used in Research Investigator jobs:
  • Authored manufacturing documents for preparation of clinical drug products; assisted GMP manufacture.
  • Developed assay for GMP analysis of product and clinical samples, advised project team on safety protocols and safety evaluation.
  • Surface Area Analysis: Established GMP status of surface area instrument.
  • Audited CRO site to make sure the method transfer complied with GMP regulations.
  • Provided complete analytical leadership and support for 1st GMP pilot runs.
  • Directed research efforts at CMOs to transfer and improve processes for commercial scale production of OLED materials under cGMP conditions.

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25. PHD

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Here's how PHD is used in Research Investigator jobs:
  • Assist PhD Candidate Crystal Bedley in research on the effect of Race in the Media and Interracial families in commercials.
  • Partnered with my PhD mentor in managing lab operations and supervising 18 staff members.

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1 PHD Jobs

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26. III

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Here's how III is used in Research Investigator jobs:
  • Performed late-stage process development on Ph II/III drug substance, including range-finding and impurity fate and purge activities.
  • Investigated second generation IIb / IIIa integrin antagonists as anti-platelet agents in support of Phase II candidates.

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27. Data Entry

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28. Small Molecules

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Here's how Small Molecules is used in Research Investigator jobs:
  • Performed purification and characterization of novel small molecules for biological evaluation in drug discovery HCV programs.
  • Developed and ran cell based and biochemical assays to identify and characterize biotherapeutics and small molecules for immunology projects.
  • Developed novel flow cytometry based high-throughput screens to identify 5 small molecules targeting cancer stem cells.
  • Research on the permeation of small molecules (drugs) through lipid bilayer membranes.

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4 Small Molecules Jobs

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29. Study Protocol

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Here's how Study Protocol is used in Research Investigator jobs:
  • Prepared study protocols, selected Phase 1 sites, monitored studies, and archived trial master files (TMFs).

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30. API

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low Demand
Here's how API is used in Research Investigator jobs:
  • Prepared repair and maintenance budget for Medicinal Chemistry, evaluated instrumentation for capital purchase and wrote their business justifications.
  • Work extensively with both vendors and internal operations groups for capital equipment purchases.
  • Solicited capital budget requests and provided input for capital budget items.
  • Contributed to campaign to rapidly establish new TSU discovery pipeline.
  • Supervised temporary employee in performing API impurity and degradation studies.
  • Focused primarily on small molecule anti-viral and anti-platelet therapies.
  • Manage outsourced projects, and interact with vendors for API sourcing, and device components based on project needs.
  • Work with various vendors for API's and synthesis of compounds.
  • Performed chemical stability and solubility studies on API by LC-UV.
  • Characterized impurities in API and Drug Product.
  • Project and people management experience leading rapid scale-up teams/activities for the production of multi-kilogram deliveries and generation of technical transfer documentation.
  • Design combination strategies for immunotherapies and evaluate targeted cancer agents as combination partners with immune modulators.
  • Performed measurements of intrapixel variation in near-infrared focal plane arrays from two vendors.
  • Established analytical capability to evaluate dispersion products which resulted into rapid product development.
  • Developed, and qualified Ion Chromatography method on Dionex IC system for seven different anion counter-ions for five different API.
  • Helped team meet aggressive API scale-up (150g) synthesis timeline for acute in vivo safety studies.
  • Developed and qualified a LC/MS/MS method for alkyl sulfate quantitation in API using Sciex API LC/MS/MS.

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31. Cros

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Here's how Cros is used in Research Investigator jobs:
  • Presented and defended data generated at appropriate cross-functional project team meetings.
  • Work extensively with cross-functional team to manufacture and supply clinical trial material to sites in both US and EU.
  • Focused on process improvement by created various Microsoft Excel sheets in the effort of providing a better work flow.
  • Entered Data from Investigators as well as hours charged on spread sheets using Excel and Microsoft Word.
  • Utilized knowledge of Microsoft Excel to design a procedure for tracking and protecting participant s personal information.
  • Created spreadsheets in Microsoft Excel to collect an abundance of data and calculate psychological statistics.
  • Lead scientist on cross functional matrix team and bench level formulation development scientist.
  • Post exposure investigations using ESEM, SFEG microscopes equipped with EDX detector.
  • Manage tech transfer project and cross-functional project teams from initiation through close.
  • Lead microscope imaging technology for dirt analysis in oils and grease.
  • Collaborated with cross-functional teams to set project strategies and goals.
  • Conduct performance evaluations for cross-functional team members, if required.
  • Work with management teams across functions to improve organization.
  • Presented results to project teams and cross-functional groups.
  • Initiated a special workgroup for postdoctoral scholars representing multiple disciples across the UM campus.
  • Demonstrated ability to direct research activities at CROs to meet development timelines/objectives.
  • Helped develop cross-functional internal biotech specializing in high throughput, biologically-inspired drug transformations.
  • Negotiated and managed contracts with CROs (Dyax and Genescript).

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32. HIV

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Here's how HIV is used in Research Investigator jobs:
  • Coordinated and selected data for clinical research project from archival data.
  • Collected photographs, criminal history, and background information from Archival data at New York Municipal Archives on The Torso Killer.
  • Design of 2nd generation HIV protease inhibitors in collaboration with Vertex Pharmaceuticals.
  • Project coordinator for HIV projects: specifically HIV Protease and NNRTI agents.
  • Experience with HIV protease and HIV NNRTI resistance.
  • Archived all drugs with anticholinergic and cholinergic effects captured from a national hospital database.

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33. CMC

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Here's how CMC is used in Research Investigator jobs:
  • Interacted with internal experts in drug development within a team matrix (clinical, CMC, manufacturing, etc.)
  • Authored reports and drug product/CMC sections in support of US and ex-US regulatory filings.
  • Participate on Due Diligence initiatives/teams focusing on CMC related issues and challenges.
  • Represented Chemical Development on cross-functional area Integrated Development project teams alongside analytical, regulatory, CMC and supply chain representatives.
  • Authored part of BLA CMC section (ipilumimab).
  • Authored the analytical CMC sections of the ABT-187 and ABT-755 BLAs.
  • Identified CMC issues around chemical synthesis and analytical QC for pegylated peptide.
  • Recognized with sanofi-aventis Special Achievement Award for identification of CMC issues for pegylated peptide.

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34. HTS

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Here's how HTS is used in Research Investigator jobs:
  • Analyzed HTS screening data and provided models aimed at facilitating initial hit selection.
  • Developed a research project on 'how the conceptualization of human rights evolved during the dictatorship in Chile during 1973-1990.'
  • Designed, developed and conducted in vitro HTS for a drug candidate that is currently undergoing clinical trial for prostate cancer.
  • Monitored staff performance in analytical, process crystallization, wet, and synthetic organic chemistry, formulation development, and HTS.
  • Advanced project team from HTS through to advanced lead milestone (acute mechanistic in vivo activity).
  • Developed HTS flow cytometry protocols to study receptor expression in breast cancer cell lines.
  • Triaged a HTS screen focusing on patentable structure classes.
  • Selected highlights: Conceived and created a synthetic amino acid dehydrogenase gene, then evolved it to reverse its product stereochemistry.

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35. Ms

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Here's how Ms is used in Research Investigator jobs:
  • Produced timely resolution of wire transfer research requests resulting from a variety of circumstances.
  • Order laboratory and diagnostic testing to evaluate etiology of symptoms.
  • Received three recognition awards for contributions to various project teams
  • Order laboratory and diagnostic testing to evaluate etiology of symptoms Dictating H&P, discharge summary and daily progress notes.
  • Compiled research and data is then formulated into a complete risk assessment report using Microsoft Office programs.
  • Proposed actions to problems, presented to plant engineer, reporting evaluations of the actions.
  • Mentored and collaborated with plant technical teams globally, transferring technology and product scale up.
  • Isolated and characterized metabolite structures through use of MS and NMR techniques.
  • Manage cross -functional Research & Development and Creative & Applications teams.
  • Executed data entry, reporting, and trending in LIMS.
  • Communicated and presented data to the teams for scientific evaluation.
  • Troubleshooted problems of fixture locating, and other failures.
  • Worked very successfully with formulation and in vivo teams to deliver high quality and result-focused test compounds for biological evaluation.
  • Participate on project teams to ensure that new analytical technology is rugged and applicable to the manufacturing environment.
  • led several programs to identify and validate disease targets for cancer, cardiovascular disease, and rheumatoid arthritis.
  • Experience with kinases and 7TMs.
  • Collaborate in a multidisciplinary research environment to address analytical issues related to biologics programs.
  • Troubleshooted problems on assembling sheetmetals of automotive body-in-white, and fitting the panels of hood, fender and decklid.
  • Used Caliper AMS 90 & Agilent 2200 capillary electrophoresis instruments as part of this process.
  • Led technical transitions meetings for the supported programs from pre-clinical discovery stage to to pre-clinical development teams.

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4 Ms Jobs

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36. NMR

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Here's how NMR is used in Research Investigator jobs:
  • Investigate the half-life of lead compounds by nuclear magnetic resonance (NMR) spectroscopy.
  • Validated this mechanism via biochemical assays and 2D NMR structural analysis.
  • research on structure determination from NMR data.

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37. GLP

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Here's how GLP is used in Research Investigator jobs:
  • Direct all day-to-day operations of a regulated GLP investigative pathology laboratory.
  • Developed, validated, and applied bioanalytical assay methods in a regulated GLP environment through the management of four direct reports.
  • Developed and managed Research Project Support services team Global Project Management: research teams, GLP and non-GLP training groups.
  • Work was conducted according to specific SOPs and protocols in the spirit of GLP.
  • Implemented compliance of GLP and cGMP regulations.
  • Improved the existing procedures that would be amenable for large-scale preparations Synthesized compounds following GLP and GMP guide lines Validated manufacturing processes
  • Train junior chemists on GLP/cGMP, analytical method development, method validation and other laboratory controls.

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38. High Throughput

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Here's how High Throughput is used in Research Investigator jobs:
  • Directed BMS-Seattle High Throughput Screening program and coordinated lead candidate follow-up between NJ and Seattle sites.
  • Developed high throughput open access LC/MS and GC/MS methods.

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1 High Throughput Jobs

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39. Elisa

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Here's how Elisa is used in Research Investigator jobs:
  • Optimized and miniaturized ELISA assay ( from 96 to 384 well/plate) for antibody detection to increase throughput screening.

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40. SAR

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Here's how SAR is used in Research Investigator jobs:
  • Provided necessary project support and resources to ensure timely progression of projects; identified yearly goals and provided evaluation of activities.
  • Collected and organized company data through various channels Assisted Sales Dept and Investigations Manager as necessary Inbound Support Calls
  • Verify previous employment, education and credentials by calling necessary departments within an organization.
  • Reviewed foreclosure and tax deed files to obtain necessary information for asset recovery.
  • Ordered necessary legal documents from various national and international courts.
  • Analyzed SAR which included data mining to advance effective changes in the molecules and improving potency and selectivity of new analogs.
  • Secured proprietary access for each client, staff for all necessary systems.
  • Investigated SAR of two novel series.
  • Collated structure and SAR studies.
  • Conducted many cell based and biochemical assays for SAR and MOA studies for the lead compound.
  • Initiated SAR development of indoles as back up candidates.
  • Explored the SAR study of thiophenol series and their prodrugs that produced initial cell active compounds.
  • Devised and synthesized key analogs to probe the SAR around oncogenic kinase targets.
  • Key contributor to the development and SAR studies of the first in vivo-active sulfhydryl based inhibitors of Ras FPTase.

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41. Immunology

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low Demand
Here's how Immunology is used in Research Investigator jobs:
  • Conducted research focused on exploratory target validation in Immunology/Respiratory areas.
  • Involved in independent research in basic immunology.
  • Supervised activities of analytical cellular and molecular immunology laboratories.

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5 Immunology Jobs

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42. SOP

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low Demand
Here's how SOP is used in Research Investigator jobs:
  • Supported equipment validation activities such as protocol review, PQ/OQ, and wrote SOP(s).
  • Developed and wrote departmental SOP's.
  • Prepared and/or revised procedural documents SOPs, Work Instructions and Guidelines as needed.
  • Work was conducted according to specific SOPs in a highly regulated environment.
  • Maintained up to date knowledge of SOPs, GMPs and site safety standards.
  • Reviewed submitted proposals for compliance and guidelines requirements * Complied with necessary SOPs and system trainings

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43. RNA

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low Demand
Here's how RNA is used in Research Investigator jobs:
  • Collaborate with internal and external clinical research team on multiple strategic investigations.
  • Published in International Journal of Innovative and Advanced Research
  • Designed and developed alternative hybridization chambers.
  • Represent the department on project teams and present data at internal department and/or other company meetings as well as external conferences.
  • Resolve cases in which financial institutions cannot locate collateral or borrowers through internal resources and established practices.
  • Utilized online research sources, such as LexisNexis, and analyze information for journalists and political consultants.
  • Grant through the United States Department of Justice and the International Association of Chiefs of Police.
  • Processed incoming/outgoing flow of funds between banks, clearing housed and internal proof areas.
  • Prepared and presented posters at internal and external meetings.
  • Summarized and interpreted analytical data to generate research reports and presentations for both internal and external use.
  • Trained flavorists in different regions, developed demos and presentations for internal and external customers.
  • Delivered talks and poster presentations in national and international scientific congress.
  • Research and investigations on checking accounts and internal emblezzements.
  • Proposed alternative chemotypes and synthesized analogs that resulted in some of the most potent and selective compounds observed for the project.
  • Managed 6 FTEs at an international CRO for 9 months directing chemical synthesis of compounds and chemical sourcing of materials.
  • Devised trial-scale as well as scale up of protein and peptide production for internal R&D needs.
  • Advocated the development of cost-saving alternative that increased yields of an intermediate for NDA drug (Alvimopan).
  • Participated in ongoing RNA-Seq studies on resistant models to identify oncogenic isoforms.
  • Direct solid state analytical chemistry projects for internal and external clients according to proposal design, timeline, and budget.
  • Research: Alternans Before Cardiac Defibrillator (ABCD) Primary Investigator: Dr. Anne Curtis/Dr.

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3 RNA Jobs

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44. Analytical Support

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low Demand
Here's how Analytical Support is used in Research Investigator jobs:
  • Provided analytical support for both marketed products and new products and stability testing.
  • Provide Leveraged analytical support to manufacturing plants.
  • Lead analytical support to DuPont hydrogen cyanide (HCN) plant in Memphis, Tennessee.
  • Lead analytical support for on-line/in-line analyzers across DuPont manufacturing site in Deepwater, NJ.
  • Provided analytical support for the high throughput In Vitro permeation and metabolism screens.
  • Provide analytical supports to various CRO's for toxicity and pharmacokinetics studies.

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1 Analytical Support Jobs

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45. QC

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low Demand
Here's how QC is used in Research Investigator jobs:
  • Support QC/QA with OOS investigations (Bulk/Drug products) as well as Pharmaceutical Technology (Technical Services) with their investigations.
  • Supported QC by performing column screening and troubleshooting API counter ion assay.
  • Performed QC analysis for polymers being manufactured at various plants.
  • Supervised the acquisition of pertinent physical chemistry data to support the Process Research, QC and Analytical Chemistry groups.
  • Implement the techniques of Raman in the warehouse through collaborative teamwork between QC laboratory and the warehouse.
  • Develop libraries in the Truscan Raman RM to perform the ID test in the warehouse instead of QC laboratory.

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46. PK

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low Demand
Here's how PK is used in Research Investigator jobs:
  • Completed PK contributions to clinical development plans.
  • Served as a co-chair of the CEDD DMPK Science Forum and active member of the Metabolite ID group.
  • Worked on the lead optimization of PKC theta antagonists with the goal of improving selectivity over PKC delta.
  • Devised and implemented chemical optimization plans, which overcame selectivity, PK, and CYP induction issues.
  • Prepared PK sections of Phase 1-3 protocols, PK analyses, and final study reports.
  • Developed HPLC methods for PKDM group.
  • Synthesized novel naphthoic amides libraries, which yielded advanced leads exhibiting excellent oral PK properties.
  • Functioned as the metabolism and pharmacokinetic liaison between project teams and the DMPK department.
  • Addressed Metabolism related in-vitro/ In-vivo and PK/ PD disconnects, and safety related issues.
  • Coordinated compound formulation, eADMET, and in vivo PK and PD studies.

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47. Animal Models

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low Demand
Here's how Animal Models is used in Research Investigator jobs:
  • Developed genuine animal models for primary dystonia.
  • Pursued research on the neurobiological mechanisms of inflammatory as well as non- inflammatory muscle pain using animal models and transgenic mice.
  • Provided the metabolic disease research area with new opportunities for profiling their drugs by applying 2D-gel electrophoresis for studying animal models.
  • Develop ex vivo assays for the characterization of Alzheimer's Disease animal models.

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1 Animal Models Jobs

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48. Oversaw

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low Demand
Here's how Oversaw is used in Research Investigator jobs:
  • Provided technical guidance to and oversaw work of less experienced scientists and other staff.

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49. Psychology

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low Demand

50. Research Data

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low Demand
Here's how Research Data is used in Research Investigator jobs:
  • Organized and presented research data in poster and lecture format at scientific meetings.
  • Presented research data and journal clubs within research group and for collaborator.

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1 Research Data Jobs

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Research Investigator Jobs

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20 Most Common Skills For A Research Investigator

Analytical Methods

12.0%

Cell Culture

9.4%

Lab Equipment

8.8%

Drug Discovery

7.2%

Research Projects

7.0%

Protein

6.6%

Clinical Trials

6.1%

Assay Development

5.9%

Biology

4.6%

Data Analysis

4.3%

PCR

3.4%

Internal Medicine

3.4%

Data Collection

3.3%

Research Study

3.3%

Hplc

2.6%

IRB

2.5%

FDA

2.4%

DNA

2.4%

R

2.4%

Background Checks

2.4%
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Typical Skill-Sets Required For A Research Investigator

Rank Skill
1 Analytical Methods 8.5%
2 Cell Culture 6.6%
3 Lab Equipment 6.3%
4 Drug Discovery 5.1%
5 Research Projects 5.0%
6 Protein 4.7%
7 Clinical Trials 4.3%
8 Assay Development 4.2%
9 Biology 3.2%
10 Data Analysis 3.1%
11 PCR 2.4%
12 Internal Medicine 2.4%
13 Data Collection 2.3%
14 Research Study 2.3%
15 Hplc 1.8%
16 IRB 1.8%
17 FDA 1.7%
18 DNA 1.7%
19 R 1.7%
20 Background Checks 1.7%
21 Drug Candidates 1.3%
22 Spss 1.3%
23 NIH 1.2%
24 GMP 1.2%
25 PHD 1.2%
26 III 1.2%
27 Data Entry 1.2%
28 Small Molecules 1.2%
29 Study Protocol 1.2%
30 API 1.1%
31 Cros 1.1%
32 HIV 1.0%
33 CMC 1.0%
34 HTS 1.0%
35 Ms 1.0%
36 NMR 0.9%
37 GLP 0.9%
38 High Throughput 0.9%
39 Elisa 0.9%
40 SAR 0.9%
41 Immunology 0.9%
42 SOP 0.8%
43 RNA 0.8%
44 Analytical Support 0.8%
45 QC 0.7%
46 PK 0.7%
47 Animal Models 0.7%
48 Oversaw 0.7%
49 Psychology 0.7%
50 Research Data 0.6%
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20,081 Research Investigator Jobs

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