Research Scientist IV
Research scientist job in Spring House, PA
Source One is a consulting services company and we're currently looking for the following individual to work as a consultant with our direct client, a global Pharmaceutical Manufacturing client in Spring House, PA.
No Third-Party, No Corp to Corp, No Sponsorship. Must be able to work in the US and must not require sponsorship for employment visa status now or in the future (e.g., FI, H1-B status)
Title: Research Scientist IV
Location: Spring House, PA
Onsite (Mon-Fri, 40 hours)
Contract Duration: 12 months, with likely extension
Pay Rate: $67.88 per hour (w2)
Key Responsibilities:
• Support membrane protein expression and purification.
• Conduct protein production, purification and characterization.
• Characterization and quality check of membrane proteins to support biotherapeutics development.
• Collaborate effectively in a multi-team environment.
• Contribute to both internal and external efforts in membrane protein production.
Education:
• Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required.
Required Skills:
• Experience with membrane protein expression and optimization, purification, and characterization of proteins
• Well-versed with analytical characterization to determine quality, conformation, purity and stability
• Knowledge of protein expression construct design and optimization, and expression platforms
• Excellent communication skills to collaborate with internal and external partners
Preferred:
• Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs
• Experience in independently operating AKTA FPLC and analytical HPLC instruments
• Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery
• Knowledge and experience with CROs for protein production
Scientist 4 - Research and Development
Research scientist job in Spring House, PA
Immediate need for a talented Scientist 4 - Research and Development. This is a 12+ Months Contract opportunity with long-term potential and is located in Spring House, PA (Onsite). Please review the job description below and contact me ASAP if you are interested.
Job ID:25-94738
Pay Range: $57 - $67/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location).
Key Responsibilities:
Support membrane protein expression and purification.
Conduct protein production, purification and characterization.
Characterization and quality check of membrane proteins to support biotherapeutics development.
Collaborate effectively in a multi-team environment.
Contribute to both internal and external efforts in membrane protein production.
Key Requirements and Technology Experience:
Skills-Experience in independently operating AKTA FPLC and analytical HPLC instruments.
Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs.
Minimum of BS Degree with a minimum of 2-4 years of academic/industry experience or MS Degree with a minimum of 1-2 years is required.
Experience with membrane protein expression and optimization, purification, and characterization of proteins
Well-versed with analytical characterization to determine quality, conformation, purity and stability
Knowledge of protein expression construct design and optimization, and expression platforms
Excellent communication skills to collaborate with internal and external partners
Proficient in protein purification optimization, detergent screening, and reconstitutions into lipid nanodiscs
Experience in independently operating AKTA FPLC and analytical HPLC instruments
Experience in generating DNA/RNA constructs and or other tools as antigen for supporting antibody discovery
Knowledge and experience with CROs for protein production
Our client is a leading Pharmaceutical Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration.
Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
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Senior Scientist, Analytical Research & Development
Research scientist job in West Deptford, NJ
Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
The Sr. Scientist is responsible for the implementation, development, and validation of analytical test methods in support of process research, and cGMP production with emphasis on development of LC, GC, GC-MS and LC/MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc) methods for small molecules, ADCs, Oligonucleotides and Peptides Major support functions include sample analysis by various analytical techniques including HPLC, GC, LC-MS/MS, GC-MS, ICP-MS, CE, SEC-MALS, CE-SDS, cIEF, NMR, KF, titrations, and instrumental and wet chemical techniques. Other duties may involve analytical method modification, development, and validation. The incumbent may function as the primary contact on one or more development projects. In- depth involvement with the project team concerning the chemistry of the project and analytical chemistry needs is expected
Core Responsibilities:
Develop and validate new analytical procedures. Independently, detects and solves complex problems of high technical difficulty.
Perform sample analysis using various analytical techniques (e.g., LC, GC, LC-MS, GC-MS, ICP-MS, ELISA, SEC-MALS, CE-SDS, cIEF, etc.), interpret results, and prepare high-quality documentation such as protocols, analytical reports, and summary reports.
Document all analyses per SOPs.
Prepare SOPs, test methods, and other GMP documentation.
Independently, detect and solve complex problems of high technical difficulty.
Apply knowledge and expertise from multiple disciplines (including QA, QC, Analytical and production) to achieve project goals.
Conduct investigations independently.
Troubleshoot analyses and instruments.
Support qualification of reference materials.
Develop new analytical procedures.
Validate analytical methods.
Prepare and review scientific reports.
Interface with internal and external clients.
Qualifications:
PhD in Analytical Chemistry or equivalent
Minimum of 8 years' experience in a GMP environment.
Minimum of 5 years' experience in method development and validation for small molecules Active Pharmaceutical Ingredients (APIs). Experience with Process Development of APIs.
Experience with LC, GC, GC-MS, LC-MS, IC, spectroscopy, and wet chemistry.
Experience mentoring staff members in an analytical department.
Formal project management training.
Experience with writing method validation protocols and reports desirable.
Experience with Microsoft Office and other complex computer software (UPLC, Empower 3) desirable.
Salary Range : $115,000 - $125,000 annual base salary
Our Commitment:
Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .
Associate Scientist - Decisional Analytics
Research scientist job in Spring House, PA
One of our large pharmaceutical clients in Spring House, PA is seeking an Associate Scientist to join their growing Decisional Analytics team within the Cell Therapy Development group under the R&D Cell & Gene Therapy organization. This group is responsible for generating rapid and robust, high throughput analytical platforms that support multiple cell therapy programs from early to late-stage clinical readiness for rapid progression of process development. This position will be focused on designing, optimizing, and executing assays to assess the attributes and quality of viral vectors and CAR-T cell therapy processes and products as a part of cell therapy manufacturing platforms. The primary function of the role is characterization of CAR-T cells, predominantly with flow cytometry. Other responsibilities include:
Developing and executing analytical assays with a particular focus on immune assays (Flow cytometry, Viral titer assays, potency and cell killing assays, ELISA, MSD platform, qPCR/dd PCR)
Actively participate with the program teams and lead efforts to design, optimize and execute bioanalytical methods to assess Cell therapy drug products during process development and product testing.
Support, develop and optimize CAR-T process development platforms with a focus on rapid decisional analytics.
Apply scientific expertise to evaluate alternative technologies, troubleshoot assays, and write technical documents involving CAR-T programs.
Support CAR-T process and development, perform cell cultures and decisional analytics assays associated with these activities as required.
Routinely support non-clinical study sample analytical testing and participate in routine lab operations, equipment maintenance, reagent qualifications, and/or other duties.
Analyze high volume data, present research findings and data to the group through both written and oral communication.
Qualifications:
Bachelor's or Master's Degree in a related field of study
Minimum of 1 year of Flow Cytometry experience
1+ years of ELISA and mammalian cell culture experience
Prior experience with CAR-T or Cell Therapy is preferred
Salary: $70,000 - $90,000 (can be flexible based off experience)
Hours: Monday-Friday, 8:00am-5:00pm
Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year
PTO: 10 PTO days, 6 paid sick days & paid Holidays
Benefits: Medical, Dental, Vision and 401K plans available
Exact compensation may vary based on several factors, including skills, experience, and education.
Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.
Oncology Early Stage Clinical Scientist (Director, Non-MD)
Research scientist job in Collegeville, PA
You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine).
Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results
Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders
Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics.
Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors
May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials.
Participate in project teams to help implement clinical development and contribute to key milestones (e.g., Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents.
Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas.
Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization.
Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations.
Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification.
Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results.
Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues.
Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR
Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies
Experience in or strong understanding of Oncology Drug Development especially in Early Development
Strong scientific writing skills and communication skills (written and verbal)
Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis.
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations.
Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance.
Experience building consensus and driving change across all levels of the organization including senior management.
Data listing review experience
Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform
This position does not require you to be medical qualified.
Perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
5-10% Travel Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
Perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Imaging Research and Development Scientist
Research scientist job in Philadelphia, PA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Organization Overview:
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Responsibilities:
Lilly Imaging/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The scientist will provide expertise for biological assay development for the discovery and characterization of novel PET imaging agents, with a focus on neuroscience or oncology imaging and other therapeutic areas. This scientist will work independently, coordinating experimental details of internal and external partnered projects, conducting experiments him/herself, performing data analysis, and presenting data to internal teams and the international scientific community.
Establish and execute imaging research projects supporting oncology, neuroscience or other drug discovery and biomarker projects
Design and conduct novel binding assays, including radioligand binding assays
Characterize and purify biological targets
Collaborate with internal project teams, implement translatable imaging biomarker assays and ensure seamless translation of projects
Publish results of research projects as appropriate
Participate in extramural scientific organizations and attend scientific symposia as well as workshops in order to continue educational/professional development
Other duties as assigned
Basic Requirements:
Degree in physical or biological sciences or imaging-related field
Bachelor's degree with min of 15 years' experience, master's with a min of 12 years' experience, or PhD in scientific field.
Experience with in vitro assay development
Peer-reviewed publications
Additional Skills/Preferences:
PhD degree preferred
Experience in Oncology or Neuroscience, preferably in molecular imaging
Experience designing and executing novel biochemical, cellular and tissue assays, including radioligand binding assays (e.g. filtration binding, ELISA/AlphaLISA, SPR and LC/MS)
Experience working with amyloidogenic proteins
Demonstrated ability to independently conceive, design and execute the characterization and purification of biological targets
Experience in drug discovery of PET molecular imaging agents
Peer reviewed publications
Willingness/desire to learn and incorporate additional technologies or therapeutic area biology to address imaging needs
Excellent communication skills (both written and verbal)
Excellent presentation skills
Strong organizational skills and ability to effectively manage multiple priorities
Creativity and critical thinking skills
Team Player
Additional Information:
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$121,500 - $198,000
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyResearch Associate
Research scientist job in West Chester, PA
LanceSoft is a nationally certified Minority Business Enterprise (MBE) that has established itself as a pioneer in providing highly scalable, cost-effective workforce solutions to a diverse set of customers across various industries in the United States. Headquartered in Virginia, LanceSoft currently operates out of several locations in the US and Canada.
Title: Research Associate
Location: West Chester, PA
Duration: 12 Months
Job Description:
OVERALL RESPONSIBILITIES:
The Research Associate - Biomaterials R&D will work in a laboratory environment performing research and development activities on in collaboration with scientists and engineers in support of R&D or product development projects for the DePuy Synthes Biomaterials organization.
POSITION DUTIES & RESPONSIBILITIES:
The individual will be actively involved in laboratory work related to physical, biological, or chemical testing of prototype medical devices, or drug-device combination products.
The individual will work in a team environment, and will use standard chemical or biological laboratory methods and electronic instruments to generate data in collaboration with other researchers.
The individual will help design experiments, write protocols, execute experiments, document data appropriately, and communicate results to the research team.
The individual will contribute to the efficient operation of laboratories, including maintaining inventories of materials and supplies, and monitoring function of lab instruments, and will provide other project or product support as needed in order to support Synthes' business demands.
The individual will know and follow all laws and policies that apply to one's job, and maintain the highest levels of professionalism, ethics and compliance at all times. They will diligently participate in our compliance program-related activities as denoted by your supervisor or our Chief Compliance Officer.
This position requires work in a Biosafety Level 2 lab.
PROFESSIONAL EXPERIENCE REQUIREMENTS:
Experience conducting laboratory experiments is required.
Experience with standard biology and chemistry methods and computerized instruments is preferred
Ability to multitask and meet deadlines in a fast-paced environment.
Must be highly motivated, well organized, team oriented, analytical and flexible.
Skilled in Microsoft PowerPoint, Word, Excel, and standard experimental analysis software.
EDUCATIONAL REQUIREMENTS:
Bachelors degree in chemistry, biology, materials science, or related discipline
BS with 3 years of experience or MS with 1 year of experience preferred.
OTHER REQUIREMENTS:
This position requires less than 5% travel.
Additional Information
Regards,
Anuj Mehta
************
Trainee - Postbaccalaureate Research Request
Research scientist job in Philadelphia, PA
The Monell Chemical Senses Center provides post-baccalaureate students with opportunities for hands-on lab research and other professional activities.
Enrollment in any post-baccalaureate program
Ability to commute to Monell (3500 Market Street, Philadelphia, 19104)
Scientist, Biotherapeutics Research & Development
Research scientist job in Spring House, PA
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at *******************
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
Innovative Medicine:
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at *******************/innovative-medicine
We are searching for the best talent for a Scientist, Cell Therapy to be located in Spring House, PA.
Purpose:
The Cell & Genetic Medicines (CGM) organization is dedicated to developing, testing, and producing high-quality new molecular entities (NMEs) through innovative cell and genetic platforms within Therapeutics Discovery. Within CGM, the CAR Screening & Lead Selection (CSLS) group plays a crucial role in screening and selecting candidates for CAR-based therapies while also providing valuable automation support to enhance efforts across the organization.
We are looking for a Scientist to join our Automation team. In this role, you will collaborate with a talented group of professionals across CGM to transition benchtop assays from manual processes to streamlined automated workflows. Your efforts will significantly contribute to increasing sample testing volume while reducing time-to-results, hands-on time, repetitive strain, and assay variability.
Moreover, you will have the opportunity to partner with stakeholders beyond CGM to translate additional workflows into automation and support the successful execution of these initiatives within the organization.
If you are passionate about making a meaningful impact in therapeutic development and enjoy working in a collaborative environment, we welcome you to apply.
You will be responsible for:
Collaborating within a cross-functional team to design, develop, and deploy laboratory automation solutions
Creating, optimizing, maintaining, and continuously improving high-throughput workflows using liquid-handling robots and integrated automation workcells
Expanding the scope of existing automation by introducing new functionalities
Evaluating novel devices/instruments/technologies for the enhancement of laboratory processes
Troubleshooting laboratory automation by liaising with internal subject matter experts and external vendors to perform root cause analysis based on thorough scientific and technical investigations
Executing automated workflows and assisting others to do so
Sharing knowledge and documenting best practices within the automation team, supporting and training end-users to independently execute automated workflows, and presenting results both within CGM and to wider audiences
Qualifications / Requirements:
Education:
M.S., or B.S. in Immunology or related field, Chemistry, Engineering, or equivalent
M.S./B.S. with a minimum 5 years of laboratory experience is required. Industry experience is preferred.
Required:
Experience operating, maintaining, developing, and optimizing in one or both of the following domains: Liquid-handling robots from Hamilton, Tecan, Beckman Coulter, Dynamic Devices, Agilent, PerkinElmer, etc.
Experience with a wide variety of cell lines, as well as demonstrated ability in aseptic cell culture techniques
Demonstrated ability to work collaboratively in cross-functional teams
Strong organizational, time management, and interpersonal skills (both written and oral), and a commitment in close collaboration with scientists, vendors, and end users across seniority levels with the ability to independently manage multiple projects in parallel
Prior experience with electronic laboratory notebooks
Preferred:
Experience with analytical assay/method development
Experience migrating biological or biochemical assays/methods onto automated systems
Experience with integrated automation workcells using scheduling software such as Biosero Green Button Go, HighRes Biosolutions Cellario, or Thermo Scientific Momentum
Experience with software for the visualization of experimental data, such as GraphPad Prism or Spotfire
Experience with flow cytometry and flow cytometry technique, automation, and software
Proven proficiency and experience in biologics (mAbs, gene therapies, cell therapies, etc.) within the pharmaceutical industry with a high level of technical understanding are preferred.
Other:
The anticipated compensation for this position is 92,000-166,000.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected vertebras and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
The anticipated base pay range for this position is :
92000-166000
Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. *********************************************
Auto-ApplyScientist, Biotherapeutics Research & Development
Research scientist job in Spring House, PA
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at *******************
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
Innovative Medicine:
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at *******************/innovative-medicine
We are searching for the best talent for a Scientist, Cell Therapy to be located in Spring House, PA.
Purpose:
The Cell & Genetic Medicines (CGM) organization is dedicated to developing, testing, and producing high-quality new molecular entities (NMEs) through innovative cell and genetic platforms within Therapeutics Discovery. Within CGM, the CAR Screening & Lead Selection (CSLS) group plays a crucial role in screening and selecting candidates for CAR-based therapies while also providing valuable automation support to enhance efforts across the organization.
We are looking for a Scientist to join our Automation team. In this role, you will collaborate with a talented group of professionals across CGM to transition benchtop assays from manual processes to streamlined automated workflows. Your efforts will significantly contribute to increasing sample testing volume while reducing time-to-results, hands-on time, repetitive strain, and assay variability.
Moreover, you will have the opportunity to partner with stakeholders beyond CGM to translate additional workflows into automation and support the successful execution of these initiatives within the organization.
If you are passionate about making a meaningful impact in therapeutic development and enjoy working in a collaborative environment, we welcome you to apply.
You will be responsible for:
Collaborating within a cross-functional team to design, develop, and deploy laboratory automation solutions
Creating, optimizing, maintaining, and continuously improving high-throughput workflows using liquid-handling robots and integrated automation workcells
Expanding the scope of existing automation by introducing new functionalities
Evaluating novel devices/instruments/technologies for the enhancement of laboratory processes
Troubleshooting laboratory automation by liaising with internal subject matter experts and external vendors to perform root cause analysis based on thorough scientific and technical investigations
Executing automated workflows and assisting others to do so
Sharing knowledge and documenting best practices within the automation team, supporting and training end-users to independently execute automated workflows, and presenting results both within CGM and to wider audiences
Qualifications / Requirements:
Education:
M.S., or B.S. in Immunology or related field, Chemistry, Engineering, or equivalent
M.S./B.S. with a minimum 5 years of laboratory experience is required. Industry experience is preferred.
Required:
Experience operating, maintaining, developing, and optimizing in one or both of the following domains: Liquid-handling robots from Hamilton, Tecan, Beckman Coulter, Dynamic Devices, Agilent, PerkinElmer, etc.
Experience with a wide variety of cell lines, as well as demonstrated ability in aseptic cell culture techniques
Demonstrated ability to work collaboratively in cross-functional teams
Strong organizational, time management, and interpersonal skills (both written and oral), and a commitment in close collaboration with scientists, vendors, and end users across seniority levels with the ability to independently manage multiple projects in parallel
Prior experience with electronic laboratory notebooks
Preferred:
Experience with analytical assay/method development
Experience migrating biological or biochemical assays/methods onto automated systems
Experience with integrated automation workcells using scheduling software such as Biosero Green Button Go, HighRes Biosolutions Cellario, or Thermo Scientific Momentum
Experience with software for the visualization of experimental data, such as GraphPad Prism or Spotfire
Experience with flow cytometry and flow cytometry technique, automation, and software
Proven proficiency and experience in biologics (mAbs, gene therapies, cell therapies, etc.) within the pharmaceutical industry with a high level of technical understanding are preferred.
Other:
The anticipated compensation for this position is 92,000-166,000.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected vertebras and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
The anticipated base pay range for this position is :
92000-166000
Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. *********************************************
Auto-ApplyScientist- Biologics
Research scientist job in Exton, PA
Job DescriptionScientist, Biologics
Full-time
Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Responsibilities:
Primary responsibilities include, but are not limited to the following:
Perform analytical and biological sample testing
• Conduct method development and validation studies
• Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency
• Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays
• Maintenance of instruments, and address technical and instrumental issues
• Assist the Principal Investigator with study conduct
• Maintain study documentation
• Meet regulatory compliance requirements
• Maintain a safe work environment
Requirements:
Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience
• At least 2 years working in a laboratory preferred
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Senior Embryologist Sign On Bonus
Research scientist job in Chesterbrook, PA
Enjoy what you do while contributing to a company that makes a difference in people's lives. Shady Grove Fertility, one of the premier fertility centers in the United States, continually seeks experienced, compassionate, and dynamic team players who are committed to delivering exceptional patient care to join our growing practice. The work we do building families offers stimulation, challenge, and personal reward.
If you're an Embryologist looking for a new opportunity to work in a fast-paced, professional environment where your talent contributes to changing people's lives, then we want to talk to you. This position requires collaborating with physicians and other medical providers by providing expert care and service for fertility treatments.
Sign on Bonus of 10K! We currently have an opening for a full-time Embryologist to work in our fast paced, high volume, Embryology Lab located in our Chesterbrook, PA office. Working Monday - Friday 7:30 AM to 4:00 PM with rotating weekends, holiday rotation. Approximately 1 weekend/month
How You'll Contribute:
We always do whatever it takes, even if it isn't specifically our “job.” In general, the Embryologist is responsible for:
Identification, assessment and culture of oocytes; sperm preparation and insemination of oocytes (conventional insemination and ICSI)
Assessment and selection embryos for transfer; embryo vitrification, warming and storage
Oocyte vitrification, warming and storage
Preparation and care of gametes/embryos throughout the laboratory process: IVF, ICSI, VIT, ET, Warming and Embryo Biopsy
Vitrification and warming of embryos at varying stages of development
Assessing fertilization and zygote quality following insemination
Familiarity with data entry into an EMR
Familiarity with MESA, PESA, TESA and TESE collection
Experience with regulatory guidelines and inspections (e.g. CLIA, FDA, TJC, CAP)
What You'll Bring:
Minimum 5 years experience in Embryology.
Must have a Bachelor's degree or higher in a relevant laboratory science.
Must demonstrate the ability to function effectively without direct supervision, and to perform laboratory services in accordance with the Laboratory Philosophy and Operating Standards.
Proven ability to access, input, and retrieve information from a computer.
Knowledge of office procedures and office machines (i.e. computer, fax, copier, etc.).
Ability to work as part of a multidisciplinary team.
Ability to work in a high standard, stressful environment.
Ability to communicate accurately and concisely.
Ability to develop interpersonal working relationships with colleagues
Must be authorized to work in the U.S.A.
More important than the best skills, however, is the right person. Employees who embrace our mission, vision, and core values are highly successful.
What We Offer:
We are proud to provide a comprehensive and competitive benefits package tailored to support the needs of our team members across all employment types:
Full-Time Employees (30+ hours/week):
Medical, dental, and vision insurance, 401(k) with company match, tuition assistance, performance-based bonus opportunities, generous paid time off, and paid holidays
Part-Time Employees:
401(k) with company match and performance-based bonus opportunities
Per Diem Employees:
401(k) with company match
At Shady Grove Fertility, we promote and develop individual strengths in order to help staff grow personally and professionally. Our core values guide us daily to work hard and enjoy what we do. We're committed to growing our practice and are always looking to promote from within. This is an ideal time to join our team!
How To Get Started:
To have your resume reviewed by someone on our Talent Acquisition team, click on the “Apply” button. Or if you happen to know of someone who might be interested in this position, please feel free to share the job description by clicking on an option under “Share This Job” at the top of the screen.
Associate Scientist (Biologic Discovery)
Research scientist job in Spring House, PA
Our large pharmaceutical client is seeking an Associate Scientist to join their growing Biophysics & Molecular Attributes Group in Spring House, PA. The Biophysics & Molecular Attributes Group within Biologics Discovery uses innovative biophysical, biochemical, and mass spectrometry based analytical tools to help select best therapeutic candidates for clinical development. You will be a critical member of the Higher Order Structure (HOS) team that characterizes developability attributes like thermal stability, chemical stability, solubility, and aggregation on a broad range of biologics platforms including monoclonal antibodies, multi-specific antibodies, antibody drug conjugates, antibody radio conjugates, and other therapeutic proteins. You will design and perform experiments using a variety of technologies like HPLC, DSF, DSC, cIEF, GXII, DLS, and more.
Key Responsibilities:
Execute automated methods for biophysical and structural characterization of antibody therapeutics. Integrate robotic liquid handling systems (e.g., Hamilton, Tecan) with analytical platforms to improve efficiency, consistency, and sample throughput.
Execute analytical analysis of biologics candidates using a wide variety of technologies such as size-exclusion HPLC, plate-based HIC/Heparin binding, DSF.
Evaluate results to deliver scientifically supported conclusions and recommendations that are documented in appropriate technical reports.
Maintain lab and equipment.
Collaborate with colleagues in the global organization to support discovery projects.
Assist in developing recommendations for improving standard procedures.
Required Skills & Experience
Master's or Bachelor's degree in a relevant scientific field
2 years of experience in protein characterization (biologics/large molecules)
Hands-on expertise in using and troubleshooting analytical techniques such as HPLC, DSF, DSC, cIEF, GXII, and DLS for protein and antibody analysis
Nice to Have Skills & Experience
Protein purification
Salary: $67,000 - $75,000 (can be flexible based off experience)
Hours: Monday-Friday, 8:00am-5:00pm
Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year
PTO: 10 PTO days, 6 paid sick days & paid Holidays
Benefits: Medical, Dental, Vision and 401K plans available
Exact compensation may vary based on several factors, including skills, experience, and education.
Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.
Oncology Early Stage Clinical Scientist (Director, Non-MD)
Research scientist job in Collegeville, PA
You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine).
POSITION RESPONSIBILITIES
Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s)
Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results
Support execution for all FIH programs through proof-of concept
Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders
Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics.
Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors
Support and assist in the development of publications, abstracts, and presentations
May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials.
Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials).
Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents.
Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas.
Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization.
Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations.
Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification.
Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results.
Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues.
Perform other duties as assigned related to clinical programs.
Support functional area priorities and contribute to or lead departmental initiatives as requested.
MINIMUM QUALIFICATIONS / KEY SKILLS
Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR
MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR
BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO
Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies
Experience in or strong understanding of Oncology Drug Development especially in Early Development
Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations.
Strong scientific writing skills and communication skills (written and verbal)
Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis.
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations.
Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance.
Experience building consensus and driving change across all levels of the organization including senior management.
Data listing review experience
Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate
Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform
PREFERRED QUALIFICATION
Experience leading a team
This position does not require you to be medical qualified.
Demonstrates diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
Perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
5-10% Travel
Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
Perform complex data analysis
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Work Location Assignment: Hybrid
The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Medical
Scientist - Imaging Research and Development
Research scientist job in Philadelphia, PA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Organization Overview:
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.
Responsibilities:
Lilly Imaging/Avid Radiopharmaceuticals provides technical expertise for molecular imaging to Lilly Research Laboratories. The scientist will provide expertise for biological assay development for the discovery and characterization of novel PET imaging agents, with a focus on neuroscience or oncology imaging and other therapeutic areas. This scientist will work independently, coordinating experimental details of internal and external partnered projects, conducting experiments him/herself, performing data analysis, and presenting data to internal teams and the international scientific community.
* Establish and execute imaging research projects supporting oncology, neuroscience or other drug discovery and biomarker projects
* Design and conduct novel binding assays, including radioligand binding assays
* Characterize and purify biological targets
* Collaborate with internal project teams, implement translatable imaging biomarker assays and ensure seamless translation of projects
* Publish results of research projects as appropriate
* Participate in extramural scientific organizations and attend scientific symposia as well as workshops in order to continue educational/professional development
* Other duties as assigned
Basic Requirements:
* Degree in physical or biological sciences or imaging-related field
* Bachelor's degree with min of 10 years' experience or master's with a min of 8 years' experience in scientific field
* Experience with in vitro assay development
Additional Skills/Preferences:
* Experience with in vitro assay development
* Experience in Oncology or Neuroscience, preferably in molecular imaging
* Experience designing and executing novel biochemical, cellular and tissue assays, including radioligand binding assays (e.g. filtration binding, ELISA/AlphaLISA, SPR and LC/MS)
* Experience working with amyloidogenic proteins
* Demonstrated ability to independently conceive, design and execute the characterization and purification of biological targets
* Experience in drug discovery of PET molecular imaging agents
* Peer reviewed publications
* Willingness/desire to learn and incorporate additional technologies or therapeutic area biology to address imaging needs
* Peer-reviewed publications
* Excellent communication skills (both written and verbal)
* Excellent presentation skills
* Strong organizational skills and ability to effectively manage multiple priorities
* Creativity and critical thinking skills
* Team Player
Additional Information:
* Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status
* Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$63,000 - $162,800
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyResearch Associate- I
Research scientist job in Spring House, PA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
Responsibilities
Applicant must be experienced with animal handling and be competent in basic laboratory skills.
Candidate would be responsible for the
planning and execution of in vivo studies in support of bacterial vaccine and monoclonal antibody R&D utilizing a variety of laboratory animals
according to the company s Institutional Animal Care and Use Committee guidelines.
The ideal applicant will be able to perform daily routine tasks efficiently and accurately, and is willing to learn new techniques.
Key responsibilities of the positions involve dosing and infection by various routes of administration, bleeding (interim and terminal), small animal surgery and harvesting of tissues for bacterial quantitation.
Calculating study endpoints, summarizing and recording data, and reporting of results would be required.
In addition to having strong in vivo skills, the candidate would ideally possess basic in vitro laboratory skills
encompassing microbiology, molecular biology, biochemistry and immunology.
Qualifications
BS, BA or MA in animal science, biology or related discipline required with a minimum of two years experience;
Hands-on experience with animal studies in the vivarium setting;
A current understanding of
basic animal models of infection
would be desired;
Experience in
basic in vitro laboratory skills (microbiology, molecular biology, biochemistry and immunology) preferred;
Experience with
vaccine development including immunological assays preferred but not essential;
Excellent computer, verbal and written communication skills;
Works well in a Team environment, but has the ability to execute studies independently;
Flexibility to travel between the Springhouse, PA (Home Base) and Raritan, NJ research facilities.
Additional Information
For more information, please contact
Sneha Shrivastava
Technical Recruiter (Clinical/Scientific)
Artech Information Systems LLC
360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960
Office: ************ | Fax: ************
Connect with us on - LinkedIn | Facebook | Twitter
Scientist- Biologics
Research scientist job in Exton, PA
Scientist, Biologics
Full-time
Frontage Laboratories Inc. is an award winning, full-service, CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Responsibilities:
Primary responsibilities include, but are not limited to the following:
Perform analytical and biological sample testing
• Conduct method development and validation studies
• Perform immunoassay techniques: (ligand binding assays, ELISA, MSD, and/or RIA applicable to Pharmacokinetic and Immunogenicity studies), with proficiency
• Prepare and handle various cell lines, tissue culture media and other reagents for cell-based assays such as Neutralizing Antibody (NAb) assays
• Maintenance of instruments, and address technical and instrumental issues
• Assist the Principal Investigator with study conduct
• Maintain study documentation
• Meet regulatory compliance requirements
• Maintain a safe work environment
Requirements:
Bachelor's degree in related scientific discipline or Bachelors degree with relevant experience
• At least 2 years working in a laboratory preferred
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and benefits package including health and dental insurance, a 401(k) plan, disability insurance, and life insurance.
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Auto-ApplyScientist, Biologics
Research scientist job in Spring House, PA
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at *******************
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at *******************/innovative-medicine
Johnson & Johnson Innovative Medicine R&D is recruiting for a Scientist, Biologics located in Spring House, PA.
We are seeking a Scientist, Biologics to join our innovative team within Discovery, Product Development and Supply (DPDS).
Principal Responsibilities:
Design and execute experiments to assess high-concentration properties of lead molecules, including viscosity, concentratability, stability, aggregation, and self-association.
Set up and manage stability studies; prepare samples for biophysical analysis.
Conduct high-throughput biophysical measurements using techniques such as, NanoDSF, GXII, Chromatography (Size Exclusion (SEC), Hydrophobic Interaction (HIC), CIC), Capillary Isoelectric Focusing (cIEF), Dynamic Light Scattering (DLS), Mass photometry.
Execute methods of automation workflows: execute methods on Liquid Handlers for sample preparation (mixing, dilution, plate transfer, plate mapping).
Independently interpret and communicate experimental results to program teams and senior management.
Innovate and implement new techniques to assess developability and biophysical characteristics of therapeutic candidates.
Optimize biophysics characterization workflows to improve throughput and data quality.
Serve as a Biophysics representative on multidisciplinary project teams, contributing scientific insights and strategic direction.
Qualifications:
A minimum of a Bachelor's degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is required. Master degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is preferred.
A minimum of 5 years of relevant industry experience with a Bachelor's degree or a minimum of 3 years of relevant industry experience with a Master's degree is required.
Solid understanding of protein science and biophysical principles is required.
Hands-on experience characterizing therapeutic proteins and antibodies using a broad array of biophysical and stability techniques, including SEC, DSF, HIC, GXII, and/or DLS is required.
Experience with high-throughput liquid handling systems is preferred.
Experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required.
Must have excellent verbal and written communication skills.
Must have strong interpersonal skills.
The ability to report data and present findings to management is required.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
Auto-ApplyScientist, Biologics
Research scientist job in Spring House, PA
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at *******************
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Biotherapeutics R&D
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at *******************/innovative-medicine
Johnson & Johnson Innovative Medicine R&D is recruiting for a Scientist, Biologics located in Spring House, PA.
We are seeking a Scientist, Biologics to join our innovative team within Discovery, Product Development and Supply (DPDS).
Principal Responsibilities:
Design and execute experiments to assess high-concentration properties of lead molecules, including viscosity, concentratability, stability, aggregation, and self-association.
Set up and manage stability studies; prepare samples for biophysical analysis.
Conduct high-throughput biophysical measurements using techniques such as, NanoDSF, GXII, Chromatography (Size Exclusion (SEC), Hydrophobic Interaction (HIC), CIC), Capillary Isoelectric Focusing (cIEF), Dynamic Light Scattering (DLS), Mass photometry.
Execute methods of automation workflows: execute methods on Liquid Handlers for sample preparation (mixing, dilution, plate transfer, plate mapping).
Independently interpret and communicate experimental results to program teams and senior management.
Innovate and implement new techniques to assess developability and biophysical characteristics of therapeutic candidates.
Optimize biophysics characterization workflows to improve throughput and data quality.
Serve as a Biophysics representative on multidisciplinary project teams, contributing scientific insights and strategic direction.
Qualifications:
A minimum of a Bachelor's degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is required. Master degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is preferred.
A minimum of 5 years of relevant industry experience with a Bachelor's degree or a minimum of 3 years of relevant industry experience with a Master's degree is required.
Solid understanding of protein science and biophysical principles is required.
Hands-on experience characterizing therapeutic proteins and antibodies using a broad array of biophysical and stability techniques, including SEC, DSF, HIC, GXII, and/or DLS is required.
Experience with high-throughput liquid handling systems is preferred.
Experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required.
Must have excellent verbal and written communication skills.
Must have strong interpersonal skills.
The ability to report data and present findings to management is required.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (********************************) or contact AskGS to be directed to your accommodation resource.
Required Skills:
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression
Auto-ApplyCell Therapy Process Development Scientist (Autologous)
Research scientist job in Spring House, PA
Our large pharmaceutical clients is seeking a Scientist to join their growing Process Development team within the Cell Therapy Development organization in Spring House, PA. This person will be focused on CAR-T cell manufacturing and will spend about 80% of their time in the lab setting up and running automation instruments for T cell manufacturing (primarily Prodigy), doing manipulation with cells, sampling, and making sure equipment is running properly. They will primarily be focused on process development in CAR-T and its transition to manufacturing. In this role, the successful candidate will be involved in process design, unit operation development, and parameter optimization studies resulting in the development of new production processes. Other responsibilities include:
Design and execute process development studies using sound scientific and engineering principles to develop and improve unit operations used for production of autologous T-cell therapies,
Identify, critically assess and evaluate opportunities to improve manufacturing outcomes such as improving success rate, throughput, reducing cost, process time and product quality of the final drug product.
Lead/contribute to the design and execution of phase-appropriate process development study plans, identifying process parameters and appropriate ranges to be assessed for optimal experimental design of the study.
Investigate improvements to current processes used for T-cell selection, activation, transduction and expansion together with their impact on critical quality attributes.
Author reports detailing experimental work and summarizing results, protocols, technical reports and SOPs.
Support technology transfer activities, writing protocols, reports, and performing and coordinating activities to support successful manufacturing
Qualifications:
Minimum of a Bachelor's Degree in a related field of study
Minimum of 2 years of process development for autologous cell therapy or CAR-T manufacturing
Prior experience working with bioreactors (preferably Xuri)
Salary: $80,000-$100,000 (flexible based on experience)
Hours: Monday-Friday, 8:00am-5:00pm
Hiring Method: Multiyear contract - After 1 year on contract, the individual will have the opportunity to apply for a permanent role or have their contract renewed for another year
PTO: 10 PTO days, 6 paid sick days annually & paid Holidays
Benefits: Medical, Dental, Vision and 401K plans available
Exact compensation may vary based on several factors, including skills, experience, and education.
Benefit packages for this role will start on the 31st day of employment and include medical, dental, and vision insurance, as well as HSA, FSA, and DCFSA account options, and 401k retirement account access with employer matching. Employees in this role are also entitled to paid sick leave and/or other paid time off as provided by applicable law.