Machine Learning Researcher (LLMs)
Research scientist job in Cambridge, MA
🌍 Machine Learning Scientist | Applied ML / Deep Science | NYC
A leading science-driven venture group is building a high-impact applied ML team - and they're looking for a Machine Learning Scientist to join them. This is the kind of environment where new scientific platforms are born, supported by serious domain expertise across biology, chemistry, materials and more.
About the role
You'll design cutting-edge LLM workflows, build custom evaluation frameworks, and turn early prototypes into scalable systems that shape how scientific discovery happens.
💡 What you'll work on
Create and test LLM reasoning, planning and tool-use workflows
Build and benchmark models with rigorous, domain-aware evaluations
Scale prototypes and integrate production-ready feedback loops with scientists and engineers
🚀 What they value
Curiosity and depth in applied ML
Strong experimentation habits and clear thinking around evals
Ability to work closely with multidisciplinary teams in a high-ambition environment
If this sounds interesting, drop me a message and we'll arrange a chat.
Applied AI Scientist
Research scientist job in Boston, MA
Data and Evaluation Applied AI Scientist
(Battery Informatics and Scientific AI Systems)
$180k - $310k
A fast growing energy technology company is expanding its AI research division and is looking for a Data and Evaluation Applied AI Scientist. The team builds advanced AI systems to accelerate discovery in energy storage and next generation battery materials. This role focuses on data correctness, scientific reasoning quality, and the integrity of battery domain knowledge used to train LLMs and multi agent scientific frameworks.
The company combines material science and applied AI to develop high energy Li Metal and Li ion battery technologies. Their platform uses AI enhanced discovery to design electrolytes, model electrochemical behavior, and develop new materials with real world applications across transportation, robotics, aerospace, and long duration energy storage.
What You Will Do
• Translate complex battery materials knowledge into structured, high quality, AI trainable datasets
• Lead rigorous data validation, cleaning, and annotation processes to ensure scientific correctness
• Create benchmark datasets and design multimodal evaluation suites for model testing
• Partner with AI architecture teams to assess and refine model reasoning across chemistry, materials, and electrochemical concepts
• Apply techniques that improve correctness and alignment, including methods inspired by human feedback systems
• Ensure that AI models demonstrate accurate understanding of molecular behavior, materials interactions, and battery domain logic
• Drive the application of battery informatics principles across data pipelines and model development
What You Bring
• PhD in Chemical Engineering with a focus on lithium battery systems or in Materials Science or a closely related computational field
• Deep domain expertise in battery materials and electrochemical systems
• Strong experience converting scientific data into AI trainable structures
• Practical experience with data validation, annotation, and benchmark dataset creation
• Exposure to LLM pipelines, AI evaluation, or multi agent scientific workflows
• Background in an applied science or AI for materials role
Preferred Experience
• Hands on experience with RLHF or other model tuning and alignment techniques
• Work history in battery labs, materials informatics teams, or AI4Science groups
• Experience designing domain specific evaluation frameworks for complex AI systems
• Experience as a computational battery AI specialist
Senior DMPK Scientist
Research scientist job in Lexington, MA
Job Title: Principal Research Scientist VI
Pay rate: $120-140/hr on w2
Duration: 12 Months (possible opportunity to convert to perm after contract term)
About the Role
We are seeking an experienced DMPK Project Representative to provide scientific leadership in the discovery and optimization of small-molecule drug candidates. This role leads DMPK strategy across multiple therapeutic areas and collaborates closely with cross-functional scientific teams.
The ideal candidate is an ADME or PK/PD subject matter expert with a strong project-facing background and a track record of impactful scientific contributions.
Top Skills
3+ years in a project-facing scientific leadership role
Expertise in ADME and/or PK/PD modeling
Strong publication/abstract history in metabolism, drug interactions, or PK/PD modeling
Key Responsibilities
Serve as the DMPK representative on global, cross-functional small-molecule project teams
Provide expert guidance on experimental strategy, data interpretation, and DMPK strategy
Lead internal and external research efforts supporting drug discovery
Work closely with pharmacology, medicinal chemistry, and CRO teams
Design, troubleshoot, and interpret complex DMPK experiments (in vitro, in vivo, in silico)
Analyze sophisticated datasets and communicate findings to project stakeholders
Ensure accurate documentation and contribute to scientific reports, manuscripts, and milestone documents
Build collaborations with external scientific partners
Represent the organization as a subject matter expert at scientific conferences
Qualifications
Bachelor's degree with 18+ years experience,
OR Master's degree with 12+ years,
OR Doctoral degree with 6+ years relevant post-doc/industry experience
Deep understanding of ADME principles; PK/PD modeling or biotransformation experience preferred
Experience working with outsourced or hybrid ADME models is a plus
Strong communication skills-verbal, written, and cross-functional
Ideal Candidate
You thrive in a scientifically complex, highly collaborative environment and enjoy integrating DMPK strategy to advance drug discovery programs. You're comfortable leading projects, influencing cross-functional teams, and representing DMPK expertise internally and externally.
Senior Scientist
Research scientist job in Lexington, MA
QUALIFICATIONS:
• Bachelor's Degree within subject matter expertise required.
• 18+ years' relevant experience required, or a master's degree with 12+ years' relevant experience, or a Doctoral degree with 6+ years' post-doctoral and/or industry-relevant experience can be considered.
• Relevant required experience includes: Excellent understanding of ADME principles with knowledge of PK/PD modeling or biotransformation, highly desirable
• Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced models
• Demonstrates excellent verbal and written communication skills.
TOP SKILLS PER MGR:
1. Project-facing role (3+ years)
2. ADME or PKPD subject matter expert
ESSENTIAL FUNCTIONS:
• Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals
• Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
• Troubleshoot highly complex tasks through independent and team-based efforts
• Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
• Make independent decisions related to day-to-day experimental activities
• Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
• Analyze complex data with a high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
• Ensure proper documentation of all experiments and data
• Collaborative teamwork
• Communicate regularly with international colleagues within the Client
• Actively participate in cross-functional teams and meetings to drive project success
• Achieve business goals, share learnings, knowledge, and skills & promote cross-functional teamwork
• Share knowledge & expertise to expand team capabilities and goals
• Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
• Write and review collaborative research manuscripts, project documents, and milestone documents
• Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
• Represent the organization as NN-subject matter expert by attending and presenting at scientific conferences and global meetings
Senior Assay Development Scientist/Engineer
Research scientist job in Burlington, MA
+++
SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker.
We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing.
+++ The Opportunity +++
We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today.
This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels.
+++ What You'll Do +++
Core Assay Development
Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform.
Design, execute, and interpret experiments focused on:
Binding kinetics & equilibrium optimization
Surface functionalization strategies
Competitive assay dynamic-range shaping
Calibrator and control development (matrix selection, commutability)
Assay precision, stability, robustness
Analytical Performance & Validation
Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17).
Establish and demonstrate performance for:
Analytical sensitivity & functional limit (LoB/LoD/LoQ)
Linearity & reportable range (including hook effects, competitive assay inflection characterization)
Repeatability, reproducibility, and nested CV analysis
Interference and cross-reactivity studies
Matrix equivalency & recovery studies
Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks).
Cross-Functional Integration
Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance.
Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing.
Documentation & Execution
Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations.
Present results across the company to inform design decisions and product milestones.
+++ What We're Looking For +++
Technical Background
PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields.
Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus.
Demonstrated ability to independently solve complex analytical and biochemical problems.
Hands-on experience with complex analytical workflows, assay automation, and instrumentation.
Strong understanding of calibration design, commutability, and control strategies.
Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks.
Regulatory & Platform Experience (Bonus)
Experience with IVD development, ISO 13485, or 21 CFR 820.
Experience with POC or novel-platform assay development.
Knowledge of label-free sensors, waveguides, or photonic resonance systems.
Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation.
Personal Traits
Strong scientific intuition paired with rigorous data discipline.
Thrives in a fast-paced, milestone-driven startup environment.
Creative problem solver willing to challenge established assay paradigms.
High integrity, willingness to own outcomes, and a collaborative mindset.
+++ Why This Role Is Unique +++
Most assay developers spend their careers optimizing assays on platforms that already exist.
At SiPhox, you will:
Build the first generation of photonic immunoassays deployed in consumer health.
Design assays whose constraints are shaped by semiconductor physics as much as biochemistry.
Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins.
See your work ship in a product used at home by real people, not just research labs.
If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
Senior Food Scientist
Research scientist job in Ayer, MA
MUST HAVES:
Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus).
5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries.
Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company.
Strong background in food science, ingredient interactions, and process impact on nutrient stability.
Knowledge of food safety standards and aseptic processing
Computational Biology / Bioinformatics / Machine Learning Postdoc - Single Cell and Spatial Technologies
Research scientist job in Boston, MA
The Vlachos Lab and the Spatial Technologies Unit (************************** are currently looking for talented postdoctoral researchers to lead large-scale spatial/single cell initiatives within our research program as well as to devise novel AI/ML and computational biology methods that will enable us to bring these two novel technologies closer to translation. The researcher will have the ability to leverage some of the most extensive single cell and spatial transcriptomic datasets to date, generated in-house.
Available projects revolve around cancer immunology, novel immunotherapies (CAR-T, bi-specifics, mRNA cancer vaccines), and autoimmunity research. We generate extensive data and employ, develop, utilize cutting-edge artificial intelligence and machine learning (AI/ML) to generate next-generation insights for novel targets or patient stratification.
The Vlachos lab is also part of large scale initiatives, such as the Human Biomolecular Atlas Project (HuBMAP - ************************** enabling the postdoctoral researcher become an integral part of the single cell and spatial community.
Local and International Applicants are encouraged to apply
The Postdoc Single Cell and Spatial Technologies Bioinformatician will have the chance to be incorporated in cutting-edge research conducted in the Vlachos Lab, the Spatial Technologies Unit (**************************, in Beth Israel Deaconess Medical Center, Harvard Medical School, and the Broad Institute of MIT and Harvard.
The position aims for candidates with a strong quantitative and computational background with extensive experience in genomics/transcriptomics (analysis of different bulk/single cell/spatial Next Generation sequencing Techniques as well as development of novel methods). A strong background in machine learning applications is considered a plus.
Our location within the CRI, the first Institute for RNA Medicine in Boston, Harvard Medical School, and the Broad Institute of MIT and Harvard, creates a unique environment for avant-garde research and scientific growth. The researcher will receive training on research, grant writing, career development, and mentoring. She/he will have the opportunity to lead impactful projects and collaborate directly with an extensive network of leading researchers and companies in the US and internationally. Successful applicants will receive a competitive remuneration and benefits package.
Essential Skills
· Extensive experience in handling and analyzing Next Generation Sequencing data
· PhD in a relevant subject area (Computational Biology, Population Genetics/Genomics, Bioinformatics, Biostatistics)
· Strong quantitative background (e.g. BSc in Computer Science, Applied Math, Engineering, Biostatistics)
· Experience in bioinformatics/data analysis using R/Bioconductor
· Experience in linux-based environments and high-performance computing
· Proven experience in AI/ML solutions
· Great programming skills
· Effective science communication
Ideal Skills
· Single cell and/or spatial -omics data analysis experience
· Strong publishing record
· Theoretical and practical AI/ML background
· Lead and coordinate extensive projects
For methods builders we also welcome links to github/bitbucket pages, and relevant bioinformatics/computational biology/machine learning community contributions.
We are an equal Opportunity Employer and we welcome applications from women, persons with disabilities, protected veterans, and members of minority groups. International applicants are welcome to apply.'
Senior Research Scientist - Computational Wind Engineering
Research scientist job in Norwood, MA
Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection.
Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research.
The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research.
This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering.
Responsibilities:
Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions.
Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements.
Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies.
Publish and present research in peer-reviewed journals and at scientific or industry conferences.
Contribute to strategic planning and innovation in wind engineering research initiatives.
PhD degree. Mechanical, Civil, Aerospace Engineering or related fields.
Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent).
Proficient in programming languages such as C++, Python, R, MATLAB.
Skilled in high-performance computing (HPC) and parallel computing environments.
Experience with wind tunnel testing or field measurements is highly desirable.
Familiarity with relevant building codes and standards is a plus.
Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively.
The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more.
FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.
Auto-ApplyEquity Research Associate - Biotechnology
Research scientist job in Boston, MA
Responsibilities:
Conducting proprietary research evaluating biotech companies' therapeutic pipeline by analyzing scientific literature, attending medical conferences, and consulting industry experts
Writing research reports for initiations of coverage, analysis of data, deep dive in disease/ technology/ IP/ regulation/ policy, and industry/ company news
Building and maintaining financial models
Conceiving and executing on differentiated project ideas
Interfacing with company management teams, internal sales and trading personnel, and institutional investors
Candidate should understand that the team is highly motivated to become top-ranked in the biotech equity research
Qualifications:
~1+ years of biopharmaceutical investment research, consulting, or industry; prior experience in biopharmaceuticals equity research with full license is a plus
Motivated to rise in the sell-side industry in the long-term
Advanced degree (PhD/MD/ PharmD) in life sciences preferred, though not required; a strong academic track record is essential
Proficiency in written/verbal communication
Experience building financial models using excel a required on-the-job skill; prior experience is a plus
Motivated, hard-working, attention to detail, team player
Can type >120 words per minute
Primary Location Full Time Salary Range of $100,000 - $120,000.
Auto-ApplyResearch Scientist II, Cancer Cell Model Development and Resistance Project
Research scientist job in Cambridge, MA
General information Location Cambridge, MA Ref # 43395 Job Family Research Date published 12/09/2025 Time Type Full time Pay Range 100,000 - 140,000 Usd Annual Description & Requirements The Broad Institute of MIT and Harvard is the world's leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. We seek to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.
We are seeking a highly motivated and innovative scientist to lead collaborative initiatives in partnership with the Cancer Dependency Map and Cancer Cell Line Factory programs and the Sellers and Getz labs at the Broad Institute. The primary goal of this role is to develop advanced laboratory cellular models to enable functional genomics, drug screening, and drug resistance studies. Our current focus is on deriving 3D models for pediatric and rare cancers, with an initial pilot to generate cancer-resistant cell lines for major oncology drugs. This work will lay the foundation for expanding cancer cell line diversity through additional grant funding and external collaborations. The ideal candidate will be a proactive, curious scientist with a strong background in cell biology, patient-derived cancer models, drug resistance research, and platform development. This position also offers the opportunity to build leadership skills while working closely with Senior Group Leaders.
Qualified candidates should have:
A Ph.D.in a biological science (such as cell biology, biochemistry, cancer biology, or a related field) and a completed or soon-to-be-completed postdoctoral fellowship in a similar field.
2+ years of experience as a postdoc or in the industry.
Excellent organizational and time management skills with strong attention to detail.
Experience in cell biology with a focus on method development, team management, and mentoring junior research associates is highly desirable.
Required Skills:
Self-motivated and curious, with the ability to lead scientific research effectively.
Demonstrated excellent problem-solving and communication skills with leadership, colleagues, and junior research associates.
Track record of independently delivering scientific results.
Expertise in molecular and cell biology techniques, including flow cytometry, immunofluorescence staining, Western blotting, ELISA, HTS cell culturing, 3D cell culturing, drug testing, etc.
Impeccable and efficient experimental design, assay development, and execution.
Strong commitment to "leading from the bench".
Excellent interpersonal, written, and oral communication skills, perform detailed data analysis, and accurate record-keeping to support the cell model team members.
Extensive experience in following and improving assay protocols is preferred.
Responsibilities:
Lead experimental design for cell model development, implement newly developed protocols, and conduct proof-of-concept studies to evaluate feasibility and optimize workflows.
Serve as the technical lead and subject matter expert for cell model development efforts, driving strategic improvements to enhance efficiency, success rates, and overall platform capabilities.
Validate cell models through sequencing technologies and oversee model fidelity assessments using flow cytometry, immunofluorescence, western blotting, and other relevant assays in collaboration with internal Scientists and Research Associates.
Lead drug resistance modeling projects to establish oncology drug-resistant clones for functional genomics analyses.
Manage and mentor Research Associates, fostering scientific and professional growth while ensuring high-quality data generation.
Collaborate with Sellers Lab, Getz Lab, Cancer Dependency Map, PRISM drug screening, Cancer Genomics, and Cancer Data Sciences teams to advance research initiatives and share expertise.
Coordinate closely with cancer genomics core staff to integrate experimental data with genomic insights for comprehensive analysis and interpretation.
Identify opportunities for platform innovation and expansion to address emerging scientific needs and challenges.
Partner with internal teams on large-molecule discovery and validation efforts to support broader oncology research goals.
The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact ***************************** for assistance.
Biology Scientist
Research scientist job in Cambridge, MA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
• The purpose of this position is to provide support in evaluating various rodent genetic backgrounds in eliciting robust immune response within GBT.
• By performing phenotypic analysis of B cell compartment, deep sequencing of B cell repertoire, and studying antibody responses from immunized rodents, we will be able to understand the utility of these animals in biotherapeutic development.
• The incumbent, under the supervision by Pharmaceutical scientist, will be involved in the evaluation of the animals through the use of various immunogens, immunization approaches, and characterization method
Specific job description:
• Perform phenotypic analysis of lymphocyte compartments of rodents
• Perform deep sequencing of B cell repertoire of animals and analyze repertoire diversity pre and post immunization
• Immunize rodents using various strategies
• Characterize antibodies diversity post immunization
• Clone and express desired monoclonal antibodies for further analysis
Experience:
• Knowledge and work experience in the B cell phenotypic analysis by Flow Cytometry
• Knowledge and work experience in hybridoma generation
• Knowledge and work experience in rodent primary B cell culture
• Knowledge and work experience in Ig cloning from B cell
• Knowledge and work experience in affinity purification of polyclonal antibodies
• Knowledge and work experience in screening and functional assay development for selecting specific monoclonal antibodies
• Work experience in NGS of Ig repertoire
• Relevant industrial experience is preferred
Specific work plan:
a) Perform all aspects of phenotypic analysis of lymphocyte compartments of rodents
b) Perform, design and analyze B cell repertoire of rodents by deep sequencing
c) Perform and design immunization strategies and generate hybridoma
d) Evaluate and characterize immune response and monoclonal antibodies from desired rodents
e) Contribute to drafting relevant documentation such as immunization protocols, phenotypic and repertoire analysis reports and laboratory methods.
Qualifications
Bachelor's degree required
Additional Information
Best Regards,
Anuj Mehta
************
Computational Biologist - Obesity Research
Research scientist job in Boston, MA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company focuses on new therapeutic approaches for the treatment of diabetes, obesity and cardiometabolic diseases. Starting from an idea, we work with partners across Lilly to discover and develop novel biologic, small molecule and nucleic acid-based therapeutics. Our focus is the patient: by understanding the biology and pathophysiology underlying disease states, we aim to address the root cause of disease, and develop breakthrough therapies. We have one of the strongest pipelines in the industry and a track record of delivering impactful medicines that improve people's lives.
Are you a computational scientist passionate about addressing some of the most pressing global health challenges of our time? Do you stay current with the latest advances in metabolic disease research and obesity pathophysiology? Are you eager to apply pioneering computational and statistical approaches to analyze multi-omics data and unravel the complex biology of obesity, adipose tissue function and metabolic dysregulation?
The computational biology role within DOCTA is an exciting opportunity for a team-oriented scientist with deep expertise in obesity biology and computation methods to drive therapeutic discovery in metabolic diseases. In this hands-on role, you will work cross-functionally with researchers across DOCTA to design and implement multi-omic studies specifically focused on obesity pathophysiology, energy regulation, adipose tissue biology, metabolic pathway dysregulation and CNS pathways concerning obesity. You will collaborate closely with experimental project leads and scientific domain experts to drive scientific discovery through the comprehensive analysis of single-cell genomics data from preclinical models and human studies. In this role, you will not only apply established computational methods to understand obesity pathophysiology and identify novel therapeutic targets in metabolic pathways, but also pioneer the application of innovative AI/ML approaches to extract deeper biological insights from complex multi-modal datasets. The successful candidate will have the opportunity to directly impact the DOCTA pipeline, ultimately driving the scientific field forward and bringing innovative therapies to patients.
Key Responsibilities:
Design and complete studies using omics-related data sources, including RNA-seq, spatial transcriptomics, single-cell omics, proteomics, functional genomics, metabolomics, and more.
Integrate standard analytical approaches as well as emerging AI/ML models to answer scientific questions of high-dimensional data
Partner with discovery statistics team to create novel analytical frameworks for high-throughput studies and develop specialized methodologies to enhance insights from small-sample datasets.
Stay up-to-date on current technical and scientific advances through deep understanding of the literature and attendance of relevant technical and disease-related conferences
Clearly communicate complex results to cross-functional partners in a prompt and transparent manner
Perform ad-hoc bioinformatics analyses and data visualizations as needed
Work collaboratively with other Data Sciences and Computational Biology (DSCB) scientists to develop innovative, best in class computational workflows and data repositories for advanced analyses
Engage in code and documentation review within the team and across other teams within the DSCB team
Adhere to industry-standard protocols for scientific project documentation
Basic Requirements:
PhD or equivalent in Computational Biology, Bioinformatics, Biomedical Informatics, or related field with 2+ years of experience post-PhD in relevant disease area.
Additional Skills/Preferences:
Strong track record of execution of computational biology and/or bioinformatics-based projects, potentially including RNA-seq, metabolomics, multi-omics, human genetics, proteomics, AI/ML, and other related research modalities required
Prior experience and deep expertise in obesity and related areas, preferably with data from preclinical models, patient cohorts or cell lines preferred
Expertise in programming languages including R and Python and experience with workflow management systems such as Nextflow required
Experience developing production-grade bioinformatics pipelines, including working with standardized workflow tools preferred
Experience with implementation and maintenance of industry-standard documentation practices including Git, Confluence, JIRA, or equivalent preferred
Ability to prioritize and manage multiple competing priorities within a fast-paced environment required
The ability to communicate complex scientific and computational concepts to non-computational and non-scientist audiences required
Ability to represent the DOCTA DSCB team internally and externally required
Strongly team-oriented thinking mentality required
Prior industry experience preferred
Experience with scalable cloud computing platforms (e.g. Databricks, AWS) and big data analytics frameworks preferred
Experience with containerized technologies (e.g. Docker) for computational reproducibility preferred
Knowledge of human genetics preferred
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$138,000 - $224,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplyResearch Associate/Associate Scientist, Assay Development
Research scientist job in Woburn, MA
Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.
Research Associate/Associate Scientist:
We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs.
This role is based onsite in our lab in Woburn, MA 5 days/wk.
Responsibilities:
Test and execute immunoassay workflows on high-throughput, semi-automated platforms
Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development
Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects
Assist in data analysis
Acquire necessary equipment and supplies for various projects
Qualifications:
Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab
Direct experience running biofluid-based immunoassays and qPCR experimentation is required
Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.)
Experience characterizing and troubleshooting immunoassays
Strong proficiency in molecular biology lab techniques
General Qualifications:
Self-motivated and ability to perform complex tasks in an effective manner
Ability to follow instructions and grow in a mentorship setting
Excellent organizational and documentation skills
Desire to learn and implement new technologies
Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team
Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position.
We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.
Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.
Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
Auto-ApplyPre-Clinical Research Scientist
Research scientist job in Boston, MA
Dana-Farber Cancer Institute (DFCI) is seeking a highly motivated Pre-Clinical Scientist to support the research activities at the Experimental Therapeutics (ETx) Core and the Lurie Family Imaging Center (LFIC). The ETx Core and LFIC are co-located in a state-of-the-art 14,000 square-foot preclinical facility, fully equipped with housing and procedure rooms, as well as a suite of in vivo imaging scanners. The Pre-Clinical Scientist will integrate with a highly skilled team of Scientists and Research Associates, and report directly to the Director. The in vivo studies conducted at the facility are focused on cancer research, with an emphasis on in vivo pharmacology, the assessment of novel cancer therapeutics, and multimodality imaging of cancer, and provide key information for the improvement of cancer patient treatment and care.
The position is at 27 Dry Dock Ave, South Boston
******************************
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The successful candidate will work collaboratively and in concert with a staff of dedicated scientists, animal/imaging technologists/associates, administrative personnel, and clinical counterparts to design and execute oncology related mouse studies using various imaging modalities (BLI/MRI/SPECT/PET/CT, etc) as well as the entire spectrum of conventional (e.g., caliper measurements, clinical scoring) endpoints to evaluate pre-clinical novel cancer therapies. The Pre-Clinical Scientist will work closely with the Director to execute the vision and strategic direction of translational cancer research. The Pre-Clinical Scientist will partner with clinical affiliates to facilitate bidirectional translational cancer science. The Pre-Clinical Scientist will work closely with other Centers and Departments at Dana-Farber that are engaged in research on small animal modeling in cancer and in experimental therapeutics. The Scientist will be expected to develop research projects for presentation at national meetings and publication in peer-reviewed journals. The Pre-Clinical Scientist will build collaborations with principal investigators, other departments, and industrial partners to design experimental therapeutics studies, and will be responsible for the execution, analysis and generation of reports for studies.
**Skills and Abilities Required**
+ Hands-on experience using various cell line and PDX mouse/rat models and orthotopic models to execute in vivo workflows is highly desired.
+ Familiar with IVIS, PET/CT, MRI and other imaging approaches.
+ Demonstrated ability to deploy novel in vivo models to enable drug discovery and translational research.
+ Excellent interpersonal and communication skills with the ability to interact effectively with internal and external collaborators.
+ Demonstrated expertise in various in vitro methodologies such as immune profiling by flow cytometry, ELISA and Western blot analysis.
+ Ability to establish independent research and secure external funding
+ Full-time, M-F; hours may vary with project needs
Dana-Farber Cancer Institute supports a robust Scientist career track with multiple opportunities for advancement, leadership, and recognition. The successful candidate will be appointed to a level within the Scientist career track commensurate with his or her accomplishments and abilities. Promotion on this track will be based on achievement of goals.
+ PhD cancer biology, biology or relevant biological sciences
+ Minimum of 5 years' experience in pre-clinical pharmacology pre- or post-PhD
+ Established track record of research publications, preferably in cancer research
+ Builds productive internal/external working relationships.
+ Having wide-ranging experience, uses technical concepts and Institute objectives to resolve complex issues in creative and effective ways.
+ Works on complex issues where analysis of situations or data requires an in-depth evaluation of variable factors.
+ Exercises judgment in selecting methods, techniques and evaluation criteria for obtaining results.
+ Networks with key contacts outside our own area of expertise.
**Pay Transparency Statement**
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$80,000 - $82,900
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
**EEOC Poster**
Behavior Scientist
Research scientist job in Lawrence, MA
Established in 1980, the Greater Lawrence Family Health Center, Inc. (GLFHC) is a multi-site, mission-driven, non-profit organization employing over 700 staff whose primary focus is providing the highest quality patient care to a culturally diverse population throughout the Merrimack Valley. Nationally recognized as a leader in community medicine (family practice, pediatrics, internal medicine, and geriatrics), GLFHC has clinical sites in Lawrence, Methuen, and Haverhill and is the sponsoring organization for the Lawrence Family Medicine Residency program.
About Lawrence Family Medicine Residency Program: GLFHC was the first federally-qualified community health center in the United States to host a teaching residency program. Started in 1994, the Lawrence Family Medicine Residency is accredited through GLFHC and is affiliated with Lawrence General Hospital. From 1994 through 2021, LFMR has 210 physician graduates.
While most family medicine residencyâ¯programsâ¯are three years in length,â¯LFMR is a four-year training programâ¯that is part of a national pilot looking at training innovation. Residents spend an extra year of training toâ¯further expand their scope of practice, particularly in an area of concentration,â¯and to develop further expertise in population health, health systems management and leadership,â¯and integrating that care into communities. Resident physicians also participate in a nationally recognized curriculum where they learn to speak and provide medical care in Spanish. The goal of the training program is to train family physicians who provide comprehensive primary care to vulnerable populations and can improve the health and health equity of these communities.â¯â¯
GLFHC is currently seeking a Behavior Scientist. The Behavior Scientist teaches family residents on an individual basis, in group settings including didactic lectures, workshops, and seminars on behavioral science topics. Assists in the development and implementation of a family medicine behavioral science curriculum and professional development activities for family medicine residents. Provides residents with skills needed to maintain their commitment to practicing high quality patient-focused care within a high stress work environment. Ensures compliance with ACGME behavioral science/professional development requirements for family medicine residents. Provides residents with the tools necessary to develop the skills needed to work effectively with underserved and multi-ethnic populations. Provides clinical services in the outpatient setting inclusive of diagnostic and crisis assessment, psychological education and intervention, individual and systematic interventions and health and behavior coaching.
Qualifications
Experience with Family Medicine residency medical education.
Experience in providing integrated care with a team of physicians and a track record of working with teams of health care providers and support staff from different disciplines.
Experience providing psychotherapy to a socioeconomically challenged and ethnically underprivileged community
Interest in conducting research consistent with the complexity of issues that arise in primary care and the delivery of integrated care and associated curricular development.
Massachusetts state license.
Expertise with motivational interviewing and cognitive behavioral therapy techniques.
Bilingual in Spanish preferred (faculty development in Spanish language learning is available)
Education
Ph.D. or Psy.D. in Psychology, or LICSW with expertise in individual and family therapy.
GLFHC offers a setting that's flexible, rewarding and challenging. If you want to make an impact to the community we serve, apply today!
Machine Learning Scientist
Research scientist job in Cambridge, MA
Machine Learning Scientist - LLM Systems for Scientific Discovery
About the Team
Join the internal AI initiative of a prominent venture studio that has launched 100+ life sciences companies (including Moderna). You'll be part of a ~20-person technical team in Cambridge building advanced LLM and ML systems that accelerate scientific breakthroughs and help launch new AI-first ventures.
What Will I Be Doing:
Research & prototype novel LLM workflows (agents, reasoning systems, tool-use frameworks) tailored to scientific applications
Define success metrics and design custom benchmarks to evaluate AI systems across diverse scientific domains
Collaborate with ML engineers to scale promising prototypes into production systems
Stay at the frontier by synthesizing state-of-the-art research and validating findings through rigorous experimentation
Build feedback loops that incorporate user testing into system development
What We're Looking For:
PhD in machine learning, computer science, statistics, physics, mathematics, or related quantitative field
Research excellence in LLMs or adjacent areas (reasoning/agents, sequence modeling, representation learning, optimization) demonstrated through publications at top venues or impactful work
Hands-on ML experience with PyTorch or JAX, including reproducible experiment workflows
Strong Python skills and fluency with standard ML tools
Ability to work independently while collaborating effectively in a small team
Experience building LLM systems: agentic frameworks, RAG, multi-agent simulations, RLHF/DPO, or evaluation methodologies
Domain knowledge in chemistry, biology, physics, materials science, or related fields
What's in it for me:
Competitive Compensation: $140k-$240k dependent on experience
Work on originating and fostering breakthrough ventures transforming human health and sustainability
Relocation assistance available (typically $10k sign-on bonus)
Apply now for immediate consideration!
Senior Food Scientist
Research scientist job in Ayer, MA
Job Tittle: Senior Food Scientist
Work Authorization : US Citizen and Green Card
This role will lead the development and improvement of nutritional beverages and powders from concept to commercialization, driving innovation that ensures exceptional quality, stability, and clinical impact.
Responsibilities
Develop and optimize nutritional beverage and powder formulations that meet nutritional, sensory, and stability goals.
Partner with Medical Nutrition, Marketing, and Sales to align product design with business and patient needs.
Research and evaluate new ingredients and explore new medical nutrition opportunities.
Support leadership with technical and scientific expertise for product and clinical development.
Build vendor relationships to source ingredients that meet product requirements.
Present company research at scientific meetings and conferences.
Ensure strong intellectual property protection for new products and processes.
Follow all GMP, food safety, and workplace safety policies.
MUST HAVES:
Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus).
5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries.
Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company.
Strong background in food science, ingredient interactions, and process impact on nutrient stability.
Knowledge of food safety standards and aseptic processing
AI-generated to support your search process-please use them as guidance and apply your own best judgment when making decisions
Benefits
Competitive salary and performance-based bonus (12.5%) program
Comprehensive health, dental, and vision insurance
Paid time off and holidays
401(k) with company match
Opportunities for professional growth and advancement
Employee discount programs
Senior Research Scientist - Material Flammability, Fire Dynamics and Lithium-ion Battery Safety
Research scientist job in Norwood, MA
Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection.
The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss.
The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group.
The position is responsible for all aspects of project management including project proposals, execution, and reporting.
The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems.
The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more.
FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.
#FMG
#LI-TA1
Auto-ApplyPre-Clinical Research Scientist
Research scientist job in Boston, MA
Dana-Farber Cancer Institute (DFCI) is seeking a highly motivated Pre-Clinical Scientist to support the research activities at the Experimental Therapeutics (ETx) Core and the Lurie Family Imaging Center (LFIC). The ETx Core and LFIC are co-located in a state-of-the-art 14,000 square-foot preclinical facility, fully equipped with housing and procedure rooms, as well as a suite of in vivo imaging scanners. The Pre-Clinical Scientist will integrate with a highly skilled team of Scientists and Research Associates, and report directly to the Director. The in vivo studies conducted at the facility are focused on cancer research, with an emphasis on in vivo pharmacology, the assessment of novel cancer therapeutics, and multimodality imaging of cancer, and provide key information for the improvement of cancer patient treatment and care.
The position is at 27 Dry Dock Ave, South Boston
******************************
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities
The successful candidate will work collaboratively and in concert with a staff of dedicated scientists, animal/imaging technologists/associates, administrative personnel, and clinical counterparts to design and execute oncology related mouse studies using various imaging modalities (BLI/MRI/SPECT/PET/CT, etc) as well as the entire spectrum of conventional (e.g., caliper measurements, clinical scoring) endpoints to evaluate pre-clinical novel cancer therapies. The Pre-Clinical Scientist will work closely with the Director to execute the vision and strategic direction of translational cancer research. The Pre-Clinical Scientist will partner with clinical affiliates to facilitate bidirectional translational cancer science. The Pre-Clinical Scientist will work closely with other Centers and Departments at Dana-Farber that are engaged in research on small animal modeling in cancer and in experimental therapeutics. The Scientist will be expected to develop research projects for presentation at national meetings and publication in peer-reviewed journals. The Pre-Clinical Scientist will build collaborations with principal investigators, other departments, and industrial partners to design experimental therapeutics studies, and will be responsible for the execution, analysis and generation of reports for studies.
Skills and Abilities Required
* Hands-on experience using various cell line and PDX mouse/rat models and orthotopic models to execute in vivo workflows is highly desired.
* Familiar with IVIS, PET/CT, MRI and other imaging approaches.
* Demonstrated ability to deploy novel in vivo models to enable drug discovery and translational research.
* Excellent interpersonal and communication skills with the ability to interact effectively with internal and external collaborators.
* Demonstrated expertise in various in vitro methodologies such as immune profiling by flow cytometry, ELISA and Western blot analysis.
* Ability to establish independent research and secure external funding
* Full-time, M-F; hours may vary with project needs
Dana-Farber Cancer Institute supports a robust Scientist career track with multiple opportunities for advancement, leadership, and recognition. The successful candidate will be appointed to a level within the Scientist career track commensurate with his or her accomplishments and abilities. Promotion on this track will be based on achievement of goals.
Qualifications
* PhD cancer biology, biology or relevant biological sciences
* Minimum of 5 years' experience in pre-clinical pharmacology pre- or post-PhD
* Established track record of research publications, preferably in cancer research
* Builds productive internal/external working relationships.
* Having wide-ranging experience, uses technical concepts and Institute objectives to resolve complex issues in creative and effective ways.
* Works on complex issues where analysis of situations or data requires an in-depth evaluation of variable factors.
* Exercises judgment in selecting methods, techniques and evaluation criteria for obtaining results.
* Networks with key contacts outside our own area of expertise.
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$80,000 - $82,900
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEOC Poster
Auto-ApplyBioinformatician II
Research scientist job in Boston, MA
The **Center for Cancer Genomics** **(CCG)** at Dana-Farber Cancer Institute facilitates genomic discoveries in cancer using novel technology platforms to assist researchers in both genome-wide and gene-focused efforts. Technologies are selected and developed with a view to research-oriented ventures, as well as translational medicine and clinical relevance. Our clinical and research environments currently use state-of-the-art massively parallel sequencing assays of DNA and RNA from patient tumor samples. Data from these environments are used to advance research on both adult and pediatric cancers, improve our understanding of cancer biology, and advance the field of precision cancer medicine. This opportunity offers the chance to work at the forefront of translational cancer technologies and applications, in an informatics group that enables analyses in both arenas.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
The **Bioinformatician II** will report to CCG's Lead Informaticist and have the main responsibility of independently performing data analysis on a wide array of cancer multiomics projects ( _sc/sn RNAseq, sc ATACseq, Crispr screens, SNV/CNV, longread Oxford Nanopore Direct RNA sequencing,_ etc.) in consultation and collaboration with internal Dana-Farber research collaborators and external research partners. Some limited orchestration of automated pipelines may be required as necessary. The Bioinformatician II will have no direct reports. Dana-Farber has a wealth of local, on-premises, and cloud-based computing resources available to extensively explore the large body of data generated annually by Dana-Farber researchers and collaborators. Given these resources, the development of novel computational methods is strongly encouraged.
**MINIMUM JOB QUALIFICATIONS:**
Minimum Education:
Bachelor's degree required in a STEM field. Master's degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field.
Minimum Education:
3 Years of experience required; Master's degree with 1 year experience required; PhD with 0 years.
+ Experience with bioinformatics tools and databases for sequence alignment/analysis; germline and somatic variant calling; bulk and single-cell/nuclei RNAseq; long read sequencing (Oxford Nanopore).
+ Proficiency in programming languages commonly used in bioinformatics and data analysis, such as Python, R, and Perl. Experience with workflow languages such as WDL or Nextflow is a plus.
+ Excellent communication skills and ability to work collaboratively in multi-disciplinary team.
**Pay Transparency Statement**
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA)
$83,800 - $90,800
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
**EEOC Poster**