Research scientist jobs in La Mesa, CA

Representative responsibilities will include, but not necessarily be limited to, the following: Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays. Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations. Author and review QC analytical SOPs, protocols, and reports as needed Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures. Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated Skills: Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products. Education: BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role Experience in an FDA-regulated environment Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic Excellent organizational and communication skills Experience with JMP statistical software a plus.

, please email ********************** We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines. RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions. The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery. Duties and Responsibilities: Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform. Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery. Monitor and evaluate the performance of AI/ML models and drug discovery solutions. Utilize software engineering best practices to develop complex AI applications at scale. Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML. Proactively scope and deploy novel computational methods and digital technologies. Education and/or Experience: Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field. Expertise in deep learning and machine learning. Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow) Knowledge, Skills, and Abilities: Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience. Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods. Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs). Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins. Fluency in scientific programming and tool development with Python, R, or equivalents. Proficiency in C++ or Java is a plus. Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications. Experience with software development good practices, including code versioning, documentation, and testing. Experience with cloud computing. Creative, open-minded, and passionate about scientific research. Demonstrated ability to thrive in a team environment. Strong interpersonal, collaborative, organizational, and presentation skills. Understanding of RNA therapeutic modality discovery and development. No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California. Supervisory Responsibilities: This position does not currently have direct reports. Perks and Benefits: Generous employer-paid healthcare for Medical, Dental, and Vision. 100% Employer Paid Life, STD and LTD 401(k) Employer Match Generous Vacation and Sick Leave 13 Holidays Closed over the Christmas and New Year Holiday Break

The Physics Department at San Diego State University (SDSU) is seeking outstanding candidates for a postdoctoral researcher to join the computational materials research group of Prof. Mehmet Dogan to start as soon as possible. The successful candidate will conduct research at the intersection of machine learning, materials theory, and high-pressure physics, with emphasis on superconducting hydrides and related quantum materials. The group develops computational and data-driven methods to discover new compounds, predict stability, and understand materials properties under extreme conditions. The group is also affiliated with the SDSU Computational Science Research Center, which provides a vibrant and collegial scientific environment, as well as cutting-edge computational resources and support. The position involves: Machine learning models for crystal structure and property prediction. High-throughput workflows for hydrides and metastable phases. Dataset development and benchmarking strategies for small-data environments. Opportunities for collaboration with experimental and theoretical groups. Qualifications required: Ph.D. in physics, materials science, chemistry, engineering, or related field. Experience in electronic structure theory, specifically, density functional theory. Strong scientific computing skills. Qualifications preferred: Experience with ML for materials (GNNs, generative models). Background in high-pressure materials, hydrides, or superconductivity. Familiarity with structure prediction tools (e.g., genetic algorithms). Note: Exceptional candidates will be considered for other potential projects in computational materials. What we offer: Collaborative, research-focused environment Opportunities to mentor students and build collaborations Support for conference travel and career development The initial appointment for this position will be for 12 months. Additional 12-month extension will be available based on performance. A competitive salary along with a benefits package will be offered. Please apply at Academic Jobs Online (*********************************************** Applications will be evaluated on a rolling basis, but for best consideration, apply by 01/15/2026. If you have any questions, please contact Mehmet Dogan (***************). SDSU is the oldest institution of higher education in the San Diego region, with a campus in San Diego serving 36,000 undergraduate and graduate students. SDSU is included in the Carnegie Foundation's R1 category. SDSU is a Title IX, equal opportunity employer and does not discriminate against persons on the basis of race, religion, national origin, sexual orientation, gender, gender identity and expression, marital status, age, disability, pregnancy, medical condition, or covered veteran status.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description As a Research Associate you will support the development of novel microfluidic platforms. You will be part of a multidisciplinary team solving complex problems, working on integration issues and investigating new research areas. Candidates that are engineering with a foundation in biology are better suited for this role vs. pure biologists. Hands-on testing, integration and optimization of microfluidic systems including fluidics, hardware, firmware, software, and chemistry/reagents Quickly fabricate and test prototyped microfluidic systems Conduct system level testing, assay testing, image analysis Translate benchtop assays to prototype microfluidic systems Use standard lab instrumentation: fluorescence plate readers, fluorescence microscopes, thermocyclers, bioanalyzers, DNA sequencers, syringe pumps Develop and implement experimental test plans Record and analyze complex data sets Develop creative solutions to troubleshoot issues Willingness to be hands-on Share and record experimental results for an audience with broad technical backgrounds at technical meetings Qualifications Skills: Microfluidics Experience with prototyping microfluidic systems: 3D printers, CO2 laser, laser ablation, profilometry Demonstrated ability to understand and successfully work across multiple disciplines including engineering, biology, and software is highly desired 1-2 years of experience in a clean room 1-2 years of experience in a lab environment with wet biology or chemistry experience 1-2 years of experience in product development is highly desired Experience in a BSL-2 lab is a plus Experience with sequencing, library prep and PCR is highly desired Organized and detail oriented Clear communicator and a team player Multidisciplinary approach to problem solving A desire to be part of face paced dynamic environment Education and Experience Undergraduate degree in Mechanical Engineering, Bioengineering, Chemical Engineering, Analytical Chemistry, or Physics Additional Information Vishnu Kumar Technical Recruiter Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: *************** | Fax: ************

Job Title: Research Associate I Duration: 18+ Months Job Description: We are seeking a highly motivated contract Research Associate with strong interpersonal communication skills to conduct in vivo studies in mice in our In-Iivo Pharmacology group at La Jolla to support oncology research. RESPONSIBILITIES: • Support in vivo experiments • Flexible working hours including late shift, weekends and holidays • Strong interpersonal communication skills and team player. TECHNICAL SKILLS: • Proficient in handling mice. • Proficient in administering compounds via various routes (PO, IV, IP, SC). • Blood collection (via cheek bleed, RO, intra-cardiac). • Necropsy, collection of various tissue samples for biomarker analysis. • Experience with tumor cell subcutaneous implantation in mice and live animal surgery is a plus. • Proficient in data collection/documentation, either in electronic or hardcopy forms. Qualifications What is the minimum education experience required?: ALAT/ALATg, or BS degree in a life science with minimum 1-2 years of hands on laboratory experience in small animal experimentation. ****** • This position requires flexible working hours: A regular 5 day work week will include and require: late shift and include Sat/Sun and holidays. BID dosing schedules are central to this position. • Lift animal cages. • Handle hazardous materials and work in animal facility which will require additional medical testing and/or apparatus fitting for OSHA compliance. Thank You ! Additional Information All your information will be kept confidential according to EEO guidelines.

Job Description Pave Talent is excited to present an incredible opportunity for a Research Associate to join a cutting-edge stem cell research team in San Diego, CA! ???? This role supports pioneering work in creating induced pluripotent stem cell (iPSC) models to advance medical research for rare diseases and drug discovery. If you're eager to dive into hands-on lab work and make a difference, this is your chance! ???? About the Company Pave Talent is hiring on behalf of a dynamic San Diego-based life sciences company specializing in innovative cell-based technologies. This organization collaborates with academic, pharmaceutical, and clinical partners to deliver high-quality preclinical research solutions. Key Responsibilities Perform cell culture tasks, including iPSC and embryonic stem cell (ESC) culture and colony picking ???? Conduct molecular biology experiments such as PCR, gel electrophoresis, and DNA/RNA isolation Support iPSC reprogramming, gene editing, and differentiation under lead scientist supervision Maintain accurate data records and assist in preparing project reports Update standard operating procedures (SOPs) and perform routine lab management duties Ensure strict adherence to laboratory safety and aseptic protocols Qualifications Bachelor's degree in biology, molecular biology, or a related field preferred 0-3 years of biological lab experience with hands-on cell culture and aseptic techniques Proficiency in molecular biology techniques (e.g., PCR, electrophoresis, transfection) Strong organizational skills and attention to detail for precise record-keeping Basic computer skills, including Microsoft Office for data tracking Excellent communication and teamwork abilities for cross-functional collaboration Why Join? This company fosters a collaborative, inclusive culture where scientific innovation thrives. Enjoy a comprehensive benefits package and opportunities to grow in San Diego's vibrant life sciences hub, and you'll contribute to life-changing research! ???? Ready to shape the future of stem cell research? Apply now with your LinkedIn profile and resume to join this impactful team! ????

Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************

R&D Scientist - NGS Technology and Applications title depends on qualification and experience) Universal Sequencing Technology (UST) Corporation (universalsequencing.com), a leading NGS technology company engaged in long range/long read sequencing technology and single cell sequencing technology development, headquartered in greater Boston with a branch in San Diego, is looking for an outstanding R&D scientist to join our NGS technology and product development team in San Diego. This position is a unique opportunity to work on a cutting edge NGS library technology which enables many previously unachievable applications, especially in the clinical space. This person will work closely with a team of molecular biologists, bioinformatics scientists, instrument engineers and manufacturing specialists to develop a revolutionary single cell sequencing technology. He/she will play a key role in the development and validation of the technology as well as the commercial launch of products. He/she will also interact with external collaborators and early access customers, and provide technical support. The ideal candidate should have extensive cellular and molecular biology experience. He/she must have direct experience on cellular assay development and RNA manipulation; strong project management skills; ability to take initiative; effective verbal and written communication skills; and be an excellent team player. RNA-Seq, NGS library preparation, and sequencing data analysis skill under both Linux and Windows environment are desired; Molecular biology reagent kit development experience is a plus. Key Responsibilities: Lead NGS based single cell sequencing assay and reagent kit development Establish product quality control assays for in-process & final product test and deliver well-characterized & robust processes to manufacture Design and execute experiments, and analyze data independently Support current product improvement and commercialization Interact with collaborators and customers to promote UST technology and product Qualifications: Ph.D. in molecular biology, cellular biology, biochemistry or related fields (M.Sc. with exceptional experience will be considered) Minimum 3-years of cellular assay development and gene expression profiling experience Single cell sequencing library preparation, immune repertoire sequencing or early tumor detection experience is a plus Product development experience is preferred

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience Responsibilities: The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat Qualifications Minimum Bachelor's degree in a biological science discipline Additional Information College degree or HS Diploma with +5 years biopharmaceutical industry experience

Research Biologist needs 2-3 years experience Research Biologist requires: Degree in biology Laboratory equipment and procedures. MS Office Lab techniques Research Biochemistry Cell biology Experience in running biochemical and immunological assays. Research Biologist duties: Ø Conduct experiments to identify and validate drug targets. Ø Support assay design, optimization, validation, and data analyses. Ø Design and execute molecular and cell biology experiments. Ø Troubleshoot and analyze complex data in support of drug discovery projects. Ø Presentation of results and conclusions both orally and written.

How you will contribute: We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company. What you will be working on: Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing. Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes. Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color. Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing. Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research. What you bring to Plantible: B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering. 3 to 5+ years of industry experience in assay development in an industrial environment. Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer. Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes. A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action. Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred. Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills. Excellent verbal and written communication and presentation skills. Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment. Thrive in a fast-paced environment where the primary focus is on simplification and optimization. Choose Plantible Foods Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment. At Plantible we are continually working on our offerings to foster the best team. Check it out! Competitive health and wellness benefits Medical, Dental and Vision Insurance Discretionary Unlimited PTO Program Paid Holidays 401k Program Career Stipend Career development and growth opportunities Working in a rapidly growing, flexible and entrepreneurial environment Team building and company-wide events Financial support with your relocation, if necessary, ensuring a smooth transition Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time. If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!

Job Description In Vivo Research Associate II FLSA Status: Non-Exempt Pay Rate: $28 - $32 /hr Pharmaron (San Diego) is seeking to hire an outstanding candidate to join our Medical Device department at the Research Associate II level. The Research Associate will play an important role by supporting in vivo studies to test medical devices. This position requires a broad knowledge of animal anatomy, physiology, and biochemistry to help develop and support in vivo models to screen therapeutics and devices being developed for various indications. Responsibilities: Experience in the administration of test substances by various basic methods (i.e., oral gavage, SQ, IV, dermal, etc.) Manage and observe animals for general health and overall wellbeing. Experience in the collection of biological specimens (i.e., blood from appropriate vessels from all species of laboratory animals at the site) Able to perform study related activities in compliance with Good Laboratory Practice Regulations (GLPs), study protocols, and company policies and Standard Operating Procedures (SOPs) Review documentation to ensure functions performed meet quality control requirements. Handle, restrain, and provide care for all species of laboratory animals at the site. Perform study preparation activities, including collection tube labeling and room setup. Perform catheter placements in large animals. Perform surgical procedure: intubation, anesthesia, pain recognition and analgesia. Monitor animals under anesthesia and during post-operating monitoring and recovery. Perform biopsies and skin excisions. Perform necropsies and tissue collection. Interface with different teams, including study director, principal investigator, QC/QA, and Account Managers/Sales. Maintain accurate records in various internal databases. Support internal research projects to optimize service offerings. Perform aseptic techniques. Perform other duties as directed by management. What We're Looking For: We're seeking individuals who have strong communication skills with attention to detail who thrive in fast-paced environments. Associates degree (preferred) in veterinary technology with 3 years relevant experience. BS with at least 2 years relevant experience. Education level requirements could be amended based on relevant years of experience. Certification as a registered veterinarian technician (RVT) is a plus. Background in lab animal (in vivo) research is a must. Working knowledge of preclinical techniques and modalities will be a plus. Position requires good communication skills and attention to detail. Strong work ethic, self-motivation, and ability to adapt to a dynamic team environment. Why Pharmaron? Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. Collaborative Culture: You'll thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences. #LI-MC1

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Research Biologist requires: Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Experience in running biochemical and immunological assays. Highly motivated and agile biochemist Research Biologist duties: Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies Perform basic tasks to support tissue culture and maintenance of immune competent cell lines Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.) Work with a cross-disciplinary team for data analysis Independently execute experiments, analyze, interpret and present experimental data

In Vivo Research Associate II FLSA Status: Non-Exempt Pay Rate: $28 - $32 /hr Pharmaron (San Diego) is seeking to hire an outstanding candidate to join our Medical Device department at the Research Associate II level. The Research Associate will play an important role by supporting in vivo studies to test medical devices. This position requires a broad knowledge of animal anatomy, physiology, and biochemistry to help develop and support in vivo models to screen therapeutics and devices being developed for various indications. Responsibilities: Experience in the administration of test substances by various basic methods (i.e., oral gavage, SQ, IV, dermal, etc.) Manage and observe animals for general health and overall wellbeing. Experience in the collection of biological specimens (i.e., blood from appropriate vessels from all species of laboratory animals at the site) Able to perform study related activities in compliance with Good Laboratory Practice Regulations (GLPs), study protocols, and company policies and Standard Operating Procedures (SOPs) Review documentation to ensure functions performed meet quality control requirements. Handle, restrain, and provide care for all species of laboratory animals at the site. Perform study preparation activities, including collection tube labeling and room setup. Perform catheter placements in large animals. Perform surgical procedure: intubation, anesthesia, pain recognition and analgesia. Monitor animals under anesthesia and during post-operating monitoring and recovery. Perform biopsies and skin excisions. Perform necropsies and tissue collection. Interface with different teams, including study director, principal investigator, QC/QA, and Account Managers/Sales. Maintain accurate records in various internal databases. Support internal research projects to optimize service offerings. Perform aseptic techniques. Perform other duties as directed by management. What We're Looking For: We're seeking individuals who have strong communication skills with attention to detail who thrive in fast-paced environments. Associates degree (preferred) in veterinary technology with 3 years relevant experience. BS with at least 2 years relevant experience. Education level requirements could be amended based on relevant years of experience. Certification as a registered veterinarian technician (RVT) is a plus. Background in lab animal (in vivo) research is a must. Working knowledge of preclinical techniques and modalities will be a plus. Position requires good communication skills and attention to detail. Strong work ethic, self-motivation, and ability to adapt to a dynamic team environment. Why Pharmaron? Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. Collaborative Culture: You'll thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences. #LI-MC1

Job Description Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy