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Research scientist jobs in San Diego, CA - 449 jobs
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Sr. Staff Data Scientist
Northrop Grumman Corp. (Au
Research scientist job in San Diego, CA
At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for generations to come. Our pioneering and inventive spirit has enabled us to be at the forefront of many technological advancements in our nation's history - from the first flight across the Atlantic Ocean, to stealth bombers, to landing on the moon. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aeronautics Systems has an opening for a Staff Data Scientist to join our team of qualified, diverse individuals within the Advanced Manufacturing Technology Organization. This position can be located in San Diego or Palmdale, CA; Clearfield, UT; St. Augustine or Melbourne, FL Locations. In this role, you will Provide leadership/direction to ensure technology initiatives and opportunities for process improvements are systematically identified, pursued, and supported. Develop architectures and concepts for advanced digital technologies with a focus on implementation within Northrop Grumman Interact with customers (internal and external) Reach out and work with colleges, universities, government, supplier as part of development and improvement projects Provide leadership/direction to ensure technology initiatives and opportunities for process improvements are systematically identified, pursued, and supported. Introduce and develop new technologies for the manufacturing floor Lead projects consisting of cross functional teams of high performing engineers developing advanced systems designs and concepts. Provide technical leadership and oversight to achieve efficient, effective, and innovative Engineering solutions Apply new technologies as well as common designs and products enabling rapid development, prototyping and affordable solutions. Basic Qualifications Bachelor of Science degree in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 14 years of experience in engineering; OR Master of Science degree in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 12 years of experience in engineering; OR PhD in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 10 years of experience in engineering. Secret Clearance Periodic Re-investigation within the last 5 years Knowledge of data gathering, cleansing and transformation techniques Experience with common data science toolkits/languages such as python/R, scikit-learn, PyTorch/TensorFlow, matplotlib, numpy, C++ or python Exceptional analytical skills. Familiarity with cloud Knowledge and experience performing model uncertainty analysis, error modelling, and/or error propagation. Knowledge of best practices in data analysis. Excellent interpersonal and communication skills. Experience developing mathematical models of dynamic systems from first principles. Knowledge and experience with System Identification techniques using statistical methods to validate dynamic system models with test data. Experience performing parametric and non-parametric system identification. Experience with data acquisition systems and/or post-processing experimental test data. Knowledge and experience performing model uncertainty analysis, error modelling, and/or error propagation. Fluent with Python or Matlab. Documenting processes and maintaining data records. Preferred Qualifications Secret Clearance Periodic Re-investigation within the last 5 years Special Access Program (SAP) Current Proficient with cloud Experience in hardware/software integration of manufacturing systems Experience with querying databases and defining schemas (MS SQL) with the ability to perform data analysis and report findings Proficient in Microsoft Excel and PowerPoint Experience with high volume production ETL pipelines Experience with production assembly/fabrication including Digital Transformation, Augmented Reality/Virtual Reality, Systems Integration, IIoT, RFID, Cloud Based Applications, and/or production manufacturing operations Working knowledge of classified information systems infrastructure Digital Manufacturing experience Architecture, Design & Integration experience for engineering systems and software Technical Writing capability Project / Program Management skills (proposal creation, scheduling, budget tracking) Strong Familiarity with Process Development & Controls Ability to lead through, overcome and adapt to obstacles and challenges Ability to deal effectively with change and challenges and helps others to do the same Ability to travel 10-15% of the time Primary Level Salary Range: $178,600.00 - $310,300.00 The above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate's experience, education, skills and current market conditions. Depending on the position, employees may be eligible for overtime, shift differential, and a discretionary bonus in addition to base pay. Annual bonuses are designed to reward individual contributions as well as allow employees to share in company results. Employees in Vice President or Director positions may be eligible for Long Term Incentives. In addition, Northrop Grumman provides a variety of benefits including health insurance coverage, life and disability insurance, savings plan, Company paid holidays and paid time off (PTO) for vacation and/or personal business. The application period for the job is estimated to be 20 days from the job posting date. However, this timeline may be shortened or extended depending on business needs and the availability of qualified candidates. Northrop Grumman is an Equal Opportunity Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO and pay transparency statement, please visit *********************************** U.S. Citizenship is required for all positions with a government clearance and certain other restricted positions. #J-18808-Ljbffr$96k-147k yearly est. 3d agoAssociate Principal Scientist, Computational Chemistry
Neomorph
Research scientist job in San Diego, CA
Neomorph is seeking a highly experienced and strategically minded Associate Principal Scientist or Principal Scientist in Computational Chemistry to join our dynamic and collaborative discovery team. This is a hands‑on, individual contributor role - you will lead cutting‑edge computational chemistry efforts, roll up your sleeves to generate design hypotheses and deliver actionable insights, while influencing program strategy and scientific direction. Whether you join as an Associate Principal or Principal level depends on your years of experience and track record. In either case, you will play a key role in advancing our discovery pipeline from target assessment through candidate nomination, partnering with medicinal chemistry, structural biology, biophysics, and biology teams. Key Responsibilities Serve as the primary computational chemistry contributor on one or more drug discovery programs - designing, executing and interpreting computational workflows to support hit identification, hit‑to‑lead, and lead optimization. Integrate structure- and ligand‑based design, cheminformatics, predictive modeling and molecular simulation to propose novel compounds and drive progression of small‑molecule therapeutics (including molecular glues/degraders). Translate SAR, structural and modeling data into innovative design hypotheses; prioritize compounds and support decision‑making alongside drug discovery teams. Collaborate cross‑functionally with medicinal chemistry, structural biology, biophysics, and biology to impact program strategy, compound design and project milestones. Develop, optimize and deploy computational tools, workflows and methods (e.g., docking, MD, free energy calculations, ML/AI‑driven design) to enhance our internal capabilities and accelerate discovery. Present scientific results and strategic recommendations to internal project teams and senior leadership; provide mentorship and scientific guidance to less‑experienced colleagues (without direct line‑management responsibility). Stay abreast of emerging computational chemistry technologies, apply deep domain knowledge and help shape the future of our computational capability. Required Qualifications Associate Principal Scientist level PhD in Computational Chemistry, Theoretical Chemistry, or a related field with 6+ years, MS with 9+ years, or BS with 12+ years of relevant industry experience in drug discovery. Principal Scientist level Ph.D. in Computational Chemistry, Theoretical Chemistry, Chemistry or related field with 8+ years, M.S. with 11+ years or B.S. with 14+ years of relevant industry experience. For both levels Demonstrated hands‑on experience in small‑molecule drug discovery, with proven ability to apply molecular modeling, docking, free energy calculations, QSAR/ML, and cheminformatics to support compound design and progression. Strong record of working independently and delivering high‑quality scientific work, while also collaborating effectively in cross‑functional teams. Proficiency with commercial and/or open source computational chemistry and molecular modeling software (e.g., Schrödinger, OpenEye, AMBER, GROMACS, etc.), and fluency in scripting/programming (e.g., Python, R). Excellent communication and collaboration skills, with ability to influence project teams and senior leadership through scientific insight. Self‑starter attitude, willing to roll up sleeves and execute hands‑on work while contributing strategically. Please note: This role is not a people‑manager/line‑management position - it is a senior individual contributor role, intended for a strong computational scientist who thrives doing the work directly and influencing through scientific leadership rather than managerial oversight. Base salary range for Associate Principal Scientist is $176,000 ‒ $198,000 Base salary range for the Principal Scientist is: $187,000 - $240,000 Why Neomorph? At Neomorph, we believe scientific excellence thrives in an environment rooted in transparency, integrity, inclusivity, passion and flexibility. You'll join a growing team at the forefront of targeted protein degradation, where your contributions as an individual contributor will have significant impact on the company's discovery trajectory. What we offer Industry competitive compensation Annual target bonus Stock options 401K plan Career advancement opportunities Monthly town halls to share business and scientific updates Work Hard, Stay Well Comprehensive medical, dental, and vision plans for employees and their dependents Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution Employee Assistance Program 10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave. Supplemental pay for Pregnancy Disability Leave Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care Lifestyle Casual work environment Volunteer days off each year to spend time contributing to causes you care about Flexible work schedule Access to onsite gym Onsite space to store your bicycle (or surfboard) Have Fun! We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company‑wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day). About Us Neomorph is a venture backed biotechnology company solving critical problems in human health through the discovery and development of innovative new medicines against ‘undruggable targets'. Our team is comprised of industry leading experts in protein degradation and molecular glues who have a track record of ground‑breaking discoveries in the field. We are committed to leadership in advancing the science and technology of molecular glue drug discovery, while prosecuting a pipeline of projects through clinical development. Our patient‑first, science‑driven approach is complemented by our dedication to a supportive and collaborative work environment. Neomorph is headquartered in San Diego, California. Neomorph is committed to pursuing and hiring a diverse workforce and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of any characteristic protected by applicable federal, state or local law. Notice to agencies: Neomorph will not accept unsolicited assistance from recruiting/search agencies for this employment opportunity. Please, no phone calls or emails. All resumes submitted by recruiting or search agencies to any employee at Neomorph via email, the Internet or in any form and/or method without a valid written search/recruitment agreement in place for this position will be deemed the sole property of Neomorph. No fee will be paid in the event the candidate is hired by Neomorph as a result of the referral or through other means. #J-18808-Ljbffr$187k-240k yearly 2d agoLead In Vitro Pharmacology Scientist - GPCR Drug Discovery
Crinetics Pharmaceuticals, Inc.
Research scientist job in San Diego, CA
A biopharmaceutical company in San Diego seeks a Principal Scientist to lead an in vitro pharmacology team. Candidates should have a Ph.D. and over 8 years in drug discovery, particularly with GPCRs. Responsibilities include designing assays, managing a team, and collaborating on research projects. The competitive salary ranges from $158,000 to $197,000, with comprehensive benefits including health insurance and PTO. #J-18808-Ljbffr$158k-197k yearly 5d agoOnline Research Participant - Earn Cash for Sharing Your Views
Opinion Bureau
Research scientist job in El Cajon, CA
Take quick online surveys and earn rewards for sharing your thoughts. Join today - it's free and easy!$58k-110k yearly est. 2d agoSr Staff Data Scientist
Intuit Inc.
Research scientist job in San Diego, CA
Join the Intuit Customer Success team as a Principal Data Scientist within our Expert Network. In this role, you will help shape the AI strategy for our product support and live experiences. You'll be central to optimizing our greatest resource, our people, through innovating, experimenting, learning, pivoting, and scaling AI-driven solutions. This is a mission-critical role requiring a strategic thought partner who brings cutting-edge data science techniques and deep domain expertise to influence our Customer Success strategy and drive business growth at scale. You will partner directly with cross-functional leaders-across Product Management, Engineering, Data, Customer Success, and Service Delivery-to architect the analytical frameworks and modeling solutions that shape our Expert Network and our AI Driven platform. This role demands a strong foundation in statistical methods, machine learning, experimentation design, and causal inference, coupled with a demonstrated ability to lead with influence, navigate ambiguity, and execute with precision. Responsibilities Advanced Predictive Modeling & Machine Learning: Design, build, and deploy scalable models-includi Experimentation Science & Design: Own the end-to-end experimentation pipeline-from hypothesis generation and design (e.g., CUPED, multi-armed bandits, Bayesian Inference) to rigorous causal interpretation and impact q Causal Inference: Lead causal inference and econometric analyses to understand and influence key levers of business growth with a crisp understanding of incremental impact. Metric Design & Impact Attribution: Define and evolve success metrics using state-of-the-art measurement frameworks, ensuring that business KPIs are both predictive and causally informative. Communication: Deliver compelling, data-driven narratives to VP and Director stakeholders; distill complex findings into clear, actionable strategy recommendation ML Engineering & Native AI: Collaborate with the Central AI team to productionaliz models that enhance personalization, recommendation, or AI-assisted UX. Thought Leadership & Mentorship: Mentor senior data scientists and establish best practices in experimental design, model validation, and responsible AI usage; drive a culture of analytical excellence and scientific rigor. Strategic Influence: Demonstrate extreme ownership across cross-function initiatives, influencing product vision and delivering measurable impact through analytics innovation. Qualifications Master's or PhD degree in Computer Science, Statistics, Econometrics, Data Science, or a quantitative field. 10+ years of progressive experience in applied data science roles with increasing scope and complexity. Proven experience applying state-of-the-art machine learning and causal inference methodologies in high-impact, product-facing applications. Expert-level proficiency in SQL as well as Python or R. Demonstrated success integrating ML models into production environments, especially within personalization, recommendation, or AI-assisted UX. Deep understanding of Generative AI and other evolving technologies. Application of GenAI at scale in a production environment Deep knowledge of experimental design, including non-standard A/B testing methods, uplift modeling, and sequential testing frameworks. Hands-on experience with data visualization tools like Tableau or Qlik. Strong communication and storytelling abilities-adept at translating sophisticated analytics into strategic guidance. Proven leadership in mentoring technical talent and driving cross-team alignment through data science innovation. Intuit provides a competitive compensation package with a strong pay for performance rewards approach. This position will be eligible for a cash bonus, equity rewards and benefits, in accordance with our applicable plans and programs (see more about our compensation and benefits at Intuit : Careers | Benefits). Pay offered is based on factors such as job-related knowledge, skills, experience, and work location. To drive ongoing fair pay for employees, Intuit conducts regular comparisons across categories of ethnicity and gender. The expected base pay range for this position is: #J-18808-Ljbffr$142k-196k yearly est. 1d agoPrincipal CADD Scientist
Genesis Therapeutics
Research scientist job in San Diego, CA
Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US. What You Will Do (Key Responsibilities) Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents. Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts. Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches. Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making. Adapt to a fast-paced environment where innovation and quick iteration are encouraged. What you'll bring PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD. Deep understanding of structure-based drug design and protein-ligand interactions. Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite. Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs. Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists. We are open to remote team members too. What we offer Competitive Pay Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) Stock Option Eligibility 401(k) Plan Open PTO Policy Paid Company Holidays Subsidized lunch and snacks at our offices Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer. #J-18808-Ljbffr$112k-173k yearly est. 3d agoLead Biologics Scientist: Protein Engineering & Antibody Design
MSD Malaysia
Research scientist job in San Diego, CA
A global healthcare company based in San Diego is looking for an experienced scientist to lead biologics discovery and development. This role involves working cross-functionally with Immunology teams and external partners to innovate therapeutics focusing on antibodies and multicentric projects. Candidates should possess a strong background in protein therapeutics with respective educational qualifications and experience. A commitment to diversity and inclusion within the workplace is essential. #J-18808-Ljbffr$69k-114k yearly est. 3d agoLead Scientist, In Vitro Antibody Display & Discovery
Eli Lilly and Company
Research scientist job in San Diego, CA
A leading global healthcare firm in San Diego is seeking a highly motivated scientist to contribute to biotherapeutics development. The successful candidate will discover and engineer antibodies, oversee experiments, and utilize various molecular biology techniques. Applicants should have at least 6 years of relevant experience and a strong background in flow cytometry. This position offers competitive compensation ranging from $110,250 to $187,000 along with comprehensive benefits. #J-18808-Ljbffr$110.3k-187k yearly 4d agoPostdoctoral Scientist - Sharma Lab - Regenerative Medicine Institute
Cedars-Sinai
Research scientist job in San Diego, CA
The Postdoctoral Scientist in the Sharma Lab at Cedars-Sinai Regenerative Medicine Institute conducts advanced research using human induced pluripotent stem cells, CRISPR technology, and cardiac organoids to study cardiovascular diseases and drug toxicities. The role includes designing experiments, data analysis, mentoring, and contributing to publications under the guidance of the principal investigator. This position focuses on cutting-edge regenerative medicine with potential applications in cardiac disease modeling, drug toxicity prediction, and space biology. Job Description Join Dr. Arun Sharma and his research group as a Postdoctoral Scientist in the Cedars-Sinai Regenerative Medicine Institute! The Sharma Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for personnel to join our new and dynamic group. The mission of the Board of Governors Regenerative Medicine Institute aims to prevent and treat the world's most prevalent diseases through cell revitalization and transplantation. Work in the laboratory of Arun Sharma, PhD, focuses on applying human induced pluripotent stem cells (hi PSCs) to model cardiovascular diseases in vitro. The lab utilizes cutting-edge technologies, including hi PSCs, CRISPR/Cas9 genome editing, cardiac microfluidic organ-chips and cardiac organoids in our studies. Specifically, we have used hi PSC-derived cardiomyocytes (heart muscle cells) to model cardiac viral infections during COVID-19, examine developmental mechanisms underlying congenital heart disease and understand ways to alleviate cardiac toxicity caused by cancer drugs. In our ongoing studies, we have a unique background and interest in space biology, notably exploring ways in which stem cell biology can intersect with this emerging field. To learn more, please visit Sharma Research Lab | Cedars-Sinai. Are you ready to be a part of breakthrough research? Under the direction of Dr. Arun Sharma, the incumbent will be a part of a new collaborative project recently funded by ARPA-H, on the topic of predictive modeling of drug toxicities using pluripotent stem cells. The Postdoctoral Scientist may develop, adapt, and implement new research techniques and protocols, and will analyze, compile, and interpret data. Primary Job Duties and Responsibilities: May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds. Participate in publications and presentations as author or co-author. Designs and performs experiments, especially in regards to stem cell culture. Keeps appropriate experimental records and documentation and analyze the results with the Co-Principal Investigator. May mentor/train research associates, technicians, and students. Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments, and general lab maintenance. Operates and maintains equipment and instruments. Qualifications Education: • Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. Experience and Skills: Acquires technical and theoretical knowledge of research project and objectives during one to fiveyear post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated skills to perform experimental protocols and procedures, including detailed data collection, and analysis. Experienced in research animal husbandry and handling. Scheduling flexibility including evening, weekend and holiday rotation commitment may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 12755 Working Title : Postdoctoral Scientist - Sharma Lab - Regenerative Medicine Institute Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00 Keywords: postdoctoral scientist, regenerative medicine, stem cell research, human induced pluripotent stem cells, cardiovascular disease modeling, CRISPR genome editing, cardiac organoids, drug toxicity prediction, biomedical research, space biology$62.4k-93.6k yearly 5d agoIn Vivo Research Associate II - Large Animal
Proven Recruiting
Research scientist job in Carlsbad, CA
In Vivo Research Associate II/III, Large Animals (Contract to Hire) Looking to hone your animal surgery skills? One of San Diego's leading biotech companies is looking for a competent, reliable Research Associate to add to their dynamic team. This role offers the opportunity to build upon the foundation you've already laid in your industry experience and refine your in-vivo surgical skills. Don't miss this rare opportunity to learn from top professionals, grow into a more senior role, and excel in a challenging and supportive environment. What you will do: Administer test substances by various dosing methods, perform catheter placements, and prepare study activities. Manage and observe animals pre/post-surgery for general health and well-being. Collection of biological specimens including but not limited to skin, tissue, and blood from all animal species onsite. Who you are: AS OR BS with at least 4 years of experience with medical device studies or similar. Must have experience handling large animals (pigs, sheep, goats, rabbits, etc) Experience with dosing/injections (IM, SubQ, IV, IP, oral) Experience in a surgical environment is preferred. What does this position pay? Compensation is determined by several factors which may include skillset, experience level, and geographic location. The expected range for this role is $28.00 to $35.00 per hour. Please note this range is an estimate and actual pay may vary based on qualifications and experience. Please email your resume to sshields@provenrecruiting.com if you'd like to work alongside some of the finest professionals in the Life Sciences industry! Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!$28-35 hourly 3d agoField Technical Support Scientist (Mass Spectrometry)
Shimadzu Scientific Instruments
Research scientist job in San Diego, CA
DescriptionField Technical Support Scientist (Mass Spectrometry) Location: Los Angeles, CA Salary: $97,000 - $99,500 per year * Based on your location, a Cost of Living Adjustment (COLA) is available as part of the total compensation package Who are we? Established in 1975, Shimadzu Scientific Instruments is one of the largest suppliers of analytical instrumentation, physical testing, and environmental monitoring systems in the world. Ground-breaking scientific research, manufacturing ideas and results continue to propel Shimazu's outstanding reputation and "Excellence in Science." People dedicated to our mission have the largest impact on Shimadzu's continued growth and success. Would YOU like to join a diverse team of professionals working together with researchers, scientists and manufacturers to help better lives worldwide? What can Shimadzu offer YOU? Our Culture - A work environment that values diversity, inclusion & belonging Competitive Compensation - Day 1 Benefits & Competitive Salary Retirement Benefits - Matching 401K & Profit-Sharing Program Professional Growth - Clear pathways for Career, Leadership and Personal Development Health Benefits - Flexible Spending/Health Savings Accounts Work-Life Balance - Generous & Front-Loaded Paid Time Off Plan Education - Tuition Assistance Program for both graduate and undergraduate levels Insurance Perks - Pet Insurance, optional Identity theft, legal pre-paid and critical care buy-up insurance benefits, generous company paid life insurance & short-term disability programs Work Flexibility - Business casual Dress Attire & casual (jeans) Friday! Employee Engagement - Employee Resource Groups to network, build a sense of community and enhance one's career and personal development ADDITIONAL COMPENSATION: For Service, Technical Support, Marketing & Sales Roles: Additional compensation is available through either an Incentive and/or Commission Plan. For Employees residing in Connecticut, Massachusetts, New Jersey, and California: Additional compensation is offered through a Cost-of-Living Adjustment (COLA). Position Summary: Shimadzu Scientific Instruments is seeking an MS Technical Support Scientist to join our team and provide expert technical support for our LC-MS products. In this role, you'll support our sales teams by conducting product demonstrations, installations, training, and post-sales assistance to ensure our customers maximize the value of their instrumentation. If you thrive in a customer-facing, technical environment and enjoy collaborating with a dynamic team, this position could be the perfect fit for you. JOB FUNCTIONS INCLUDE, BUT ARE NOT LIMITED TO: Provide technical expertise during sales calls and product demonstrations. Conduct training sessions for customers and regional personnel. Run customer samples and develop application notes to showcase Shimadzu's LC-MS capabilities. Assist customers with adapting their analytical methodologies for our MS products. Oversee the regional MS demonstration inventory. Frequent travel to customer sites and regional offices (20%-50% overnight travel). Support and collaborate with regional teams and assist with training new technical support specialists. EDUCATION AND QUALIFICATIONS: Bachelor's degree in Chemistry or a related field (MS or PhD preferred). At least 1 year of laboratory experience with LC-MS instrumentation. Strong communication and problem-solving skills, ability to interpret analytical data, and excellent customer relations. Valid driver's license and willingness to travel. At Shimadzu Scientific Instruments, we believe in providing structured career paths that recognize and reward talent. If your expertise surpasses the level specified in the listed position, we offer the flexibility to upgrade positions to better suit your qualifications, accompanied by a salary adjustment. COMPENSATION AND BENEFITS: This exempt, full-time position comes with a competitive salary range of $95,000 to $97,500 annually, paid semi-monthly. Eligible benefits include a 401K matching program and discretionary yearly contributions, with detailed information provided at the final interview stage. In your first year, you will receive 10 paid vacation days, 8 paid personal days (or state sick leave in California/Puerto Rico), 8 scheduled holidays, and 3 floating holidays. After one year, you'll have access to a generous short-term disability program, with premiums fully covered by the company. Employees are insured at 100% of their salary for the first 6 weeks and 66 2/3% for weeks 7 to 12. Additional variable compensation includes an incentive plan based on performance goals, paid semi-annually in April and October, along with a potential discretionary year-end bonus. The offer also includes a company car (with a $55 deduction for personal use) and a company phone, fully funded by the employer, which remains company property but can be used for personal calls. For more details on benefits, please visit ************************** Shimadzu is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Shimadzu via email, the Internet or in any form and/or method without a valid written search agreement in place for this position (and agency was requested to work the requisition) will be deemed the sole property of Shimadzu. No fee will be paid in the event the candidate is hired by Shimadzu as a result of the referral or through other means. EEO Statement: Shimadzu Scientific Instruments (SSI) is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, color, family or medical care leave, gender identity or expression, genetic information, immigration status, marital status, medical condition, national origin, physical or mental disability, political affiliation, protected veteran or military status, race, ethnicity, religion, sex (including pregnancy), sexual orientation, or any other characteristic protected by applicable local laws, regulations and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application process, please click here . Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.$97k-99.5k yearly 4d agoResearch Associate II
BPS Bioscience
Research scientist job in San Diego, CA
BPS Bioscience is a leading biotechnology company based in San Diego, CA, specializing in the development and production of high-quality recombinant proteins, cell lines, assay kits, and related products to accelerate life science research and drug discovery. Our mission is to empower innovation by providing cutting-edge tools and services to scientists worldwide. Job Overview: This position requires the ability to perform and independently interpret protein purification experiments. The successful candidate will be tasked with duties in biochemistry, including affinity and FPLC chromatography, SDS-PAGE, Western Blot, and spectrophotometric analysis. This position will also include data entry and general lab maintenance. Responsibilities: • Perform routine, bench-scale protein purifications following standard work instructions. • Perform necessary quality control experiments, including SDS-PAGE, UV/Vis Spectroscopy and Western Blot. • Prepare buffers, reagents, and other materials necessary for experiments. • Handles documentation needed for project validation and research quality control; keeps an updated laboratory and database record with project details and information. • Ensures lab cleanliness and safety by maintaining equipment and technician attire, and keeping all samples properly labeled and stored. • Maintains common lab supply stocks as needed. • Performs internet searches to gather relevant information, record and present any relevant findings in a manner pursuant to facility protocol. • Other duties as assigned. Requirements: • Bachelor's plus 1.5 years' experience, or master's degree in biological sciences or equivalent. • Ability to calculate molar solutions, use a micropipette, follow written procedures precisely. • Knowledge of basic protein purification principles and protein analysis techniques is preferred. • Good communication, interpersonal, and teamwork skills are essential. Benefits 401k with 4% company match Companywide lunches provided quarterly Medical/Dental/Vision health insurance plans Vacation and paid holidays Why Join BPS Bioscience: Contribute to the development of cutting-edge life science tools used by researchers worldwide. Work in a collaborative, innovative, and scientifically driven environment. Opportunity to gain experience in both production and R&D workflows. Competitive compensation, benefits, and opportunities for professional growth. BPS Bioscience is an equal opportunity employer, without regard to race, color, religion, age, gender, sexual orientation, disability, or any other characteristic protected by applicable law.$56k-81k yearly est. 10d agoScientist, Protein Production and Characterization
Deerfield Management Companies
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI$98.5k-140k yearly Auto-Apply 60d+ agoScientist, Protein Production and Characterization
Director, Business Development In San Diego, California
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI$98.5k-140k yearly Auto-Apply 60d+ agoScientist, Protein Production and Characterization
Alivamab Discovery Services
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI$98.5k-140k yearly Auto-Apply 60d+ agoResearch Biologist
Global Channel Management
Research scientist job in San Diego, CA
Research Biologist needs 2-3 years experience Research Biologist requires: Degree in biology Laboratory equipment and procedures. MS Office Lab techniques Research Biochemistry Cell biology Experience in running biochemical and immunological assays. Research Biologist duties: Ø Conduct experiments to identify and validate drug targets. Ø Support assay design, optimization, validation, and data analyses. Ø Design and execute molecular and cell biology experiments. Ø Troubleshoot and analyze complex data in support of drug discovery projects. Ø Presentation of results and conclusions both orally and written.$61k-93k yearly est. 60d+ agoAssociate Scientist I, Discovery Chemistry (Bioconjugation)
Arrowhead Pharmaceuticals
Research scientist job in San Diego, CA
Job Description Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy$60k-80k yearly 25d agoSenior Bioinformatics Scientist
Invivoscribe Inc.
Research scientist job in San Diego, CA
Job Description Invivoscribe is an industry pioneer, dedicated to Improving Lives with Precision Diagnostics . Invivoscribe has been the global leader in driving international standardization of testing and accelerating patient access to the newest and best cancer treatments for over 30 years. Headquartered in sunny San Diego, California with locations across the world, we offer a comprehensive portfolio of products and services. We work with key collaborators to develop molecular assays, reagents, controls and bioinformatics tools under ISO 13485 design control that are used by over 700 clinical laboratories in over 160 countries. Our global network of laboratories offers internationally standardized next generation molecular and flow cytometry panels to support drug development and accelerate drug approvals worldwide. We work with pharmaceutical partners and international regulatory agencies across the globe to develop companion diagnostics, which are necessary to gain approval of new drugs and treatments for cancer patients. Our harmonized ISO15189 accredited and CLIA/CAP clinical laboratories offer a test menu focused on biomarkers which are clinically actionable to support therapeutic decisions, measurable residual disease (MRD) testing, patient stratification, and trial enrollment, all designed to accelerate approvals of new oncology drugs and treatments. For 30 years, we have been at forefront of precision diagnostics, and we're just getting started! We are looking to add a Senior Bioinformatics Scientist. The Senior Bioinformatics Scientist is a hands-on technical leader with advanced knowledge of scientific principles and concepts who designs, builds, and validates production-grade bioinformatics software and scalable NGS pipelines (on-prem and cloud) to diagnose and track disease (MRD) for clinical and research applications. This role independently identifies opportunities, defines technical roadmaps, and leads delivery from requirements and design through implementation, verification/validation, release, and lifecycle support. Core Responsibilities Include: Lead the design and development of bioinformatics software and pipelines to support Whole Genome Sequencing (WGS), hybrid-capture, and amplicon based NGS assays. Work in close collaboration with the R&D and clinical lab teams, representing bioinformatics from a technical leadership role. Evaluate and develop novel methods and external tools; perform benchmarking and method comparisons, and document recommendations and decisions; own projects end-to-end. Develop reproducible, testable bioinformatics software using modern engineering practices (git, code review, unit/integration tests, CI/CD, containerization), and workflow technologies (e.g., Nextflow). Apply deep Next Generation Sequencing (NGS) analytics expertise and partner with scientific stakeholders to translate bioinformatics outputs into actionable conclusions. Lead bioinformatics software development for CAP/CLIA/NYA environments, including requirements definition, design documentation, verification and validation planning/execution, traceability, change control, and release documentation. Provide technical leadership across cross-functional teams and influence others to raise team standards (R&D, clinical labs, QA/RA, DevOps). You Bring: Ph.D. degree in bioinformatics, computational biology, molecular biology, or related field with, typically, 8+ years applicable post-graduate experience. M.S. degree in bioinformatics or related field and 10+ years of applicable post-graduate experience. Equivalent combination of education and experience may be considered. Advanced proficiency with Linux and strong programming skills (Python, bash required; additional languages welcome). Experience building and/or leveraging AI agents and LLMs for various tasks and optimization of software development. Demonstrated experience designing and building production bioinformatics pipelines for WGS/WTS assays. Hands-on experience developing and operating bioinformatics software in the cloud, including workflow execution at scale and management of compute/storage costs. Experience collaborating across multi-disciplinary teams and providing technical leadership through influence (with or without direct reports). Strong foundation in statistics and quantitative analysis of biological datasets. Extensive background in immunology or cancer research is highly preferred. Experience developing software in a regulated environment is a plus (e.g. IVD, IVDR, CAP/CLIA/NYS). Proficient computer skills and good working knowledge of Microsoft Office programs and collaboration tools (Word, Outlook, Teams, Excel and PowerPoint) and the ability to learn new software programs. We Bring: A beautiful modern facility centrally located in San Diego County, with many jobs conducive to flexible scheduling and telework options. A welcoming breakroom for gathering with hosted hot/cold beverages and healthy convenience foods, and an available micro-market to get you through the day. A positive workplace culture with an emphasis on support, respect and belonging. A diverse and inclusive work environment where you will learn, grow, and make new friends. Competitive pay, discretionary bonus program, incentive stock options, generous benefit options, 401k with a fully vested employer match, and generous time off benefits. Invivoscribe is an Equal Opportunity Employer.$86k-134k yearly est. 3d agoTEMP - Scientist, Translational Biology
Neurocrine Biosciences
Research scientist job in San Diego, CA
Who We Are: At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do: Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. ( *in collaboration with AbbVie ) About the Role:The successful candidate will perform experiments and analyze data, especially rodent electroencephalography (EEG) studies related to neural circuit analysis to support drug discovery programs. In addition, this individual will run rodent behavioral assays to support programs in neuropsychiatry drug development to support target validation, lead optimization, translation, and understanding mechanisms of drug action. _ Your Contributions (include, but are not limited to): Supporting a range of activities, including in vivo and translational research Implementation and data collection of pharmaco-EEG experiments Small animal handling/dosing, drug formulation, and tissue collection Rodent survival surgery (stereotaxic) & behavioral experiments Interacting with other research areas within the company Aid in development of novel experimental approaches Conduct experiments independently on a schedule to meet required timelines Histology and imaging of slides Immunoassays and protein quantification This role is primarily focused on data collection, but may include analysis tasks for histological, timeseries, video or behavioral data Other duties assigned as required Requirements: BS/BA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and 2+ years of experience with handling and dosing animals in a laboratory setting OR MS/MA degree in biological sciences preferably related to behavioral neuroscience, pharmacology or biopsychology and some experience with handling and dosing animals in a laboratory setting PhD Preferred Small animal handling experience, including pharmacological dosing Tissue collection/dissection experience Expertise in one or more of the following techniques: In vivo electrophysiology (including EEG, EMG, LFP, spikes etc), stereotaxic surgery, functional ultrasound imaging, rodent behavioral assays (especially those pertaining to psychiatry and neurology), Immunoassays (especially Luminex and MSD) Experience in programming (Matlab, C/C++ or Python) Communication skills including data plotting and presentation Assay development and troubleshooting The pay for this role $88,000.00-$121,000.00 (paid hourly). Decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.$77k-110k yearly est. Auto-Apply 9d agoLead Scientist, In Vitro Antibody Discovery
Eli Lilly and Company
Research scientist job in San Diego, CA
A global healthcare leader in San Diego seeks a highly motivated scientist to contribute to the discovery and development of biotherapeutics. The role involves discovering and optimizing antibodies, utilizing flow cytometry, and requires strong skills in molecular biology and biochemistry. Ideal candidates should have significant industry experience and be detail-oriented, with excellent communication skills. Competitive compensation and benefits include a flexible benefits package and bonus potential. #J-18808-Ljbffr$120k-159k yearly est. 5d ago
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Learn more about research scientist jobs
How much does a research scientist earn in San Diego, CA?
The average research scientist in San Diego, CA earns between $69,000 and $181,000 annually. This compares to the national average research scientist range of $58,000 to $137,000.
Average research scientist salary in San Diego, CA
$112,000
What are the biggest employers of Research Scientists in San Diego, CA?
The biggest employers of Research Scientists in San Diego, CA are:
- ByteDance
- Vertex Pharmaceuticals
- Odyssey Systems
- RPM International
- Iambic Therapeutics
- GroupSolver
- General Atomics
- Allen Spolden
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