Staff Research Associate 2 Non-Exempt - Irvine, CA, Job ID 74113
Research Scientist Job 47 miles from Santa Monica
The Staff Research Associate II (SRA II) will assist the Cooperative Extension Advisors (Advisors) with research and education in nurseries and greenhouse production in California, focusing on irrigation and water quality management, pest management, disease management, fertilization management and other topics. The projects' audience is composed of predominantly Hispanic population and Spanish language skills are important.
Under supervision, incumbents perform a wide variety of standard repetitive laboratory and/or field experimental procedures at the full operational or journey level of skill in one field of specially; or perform a limited variety of non-standard laboratory and/or field experimental procedures requiring ingenuity, resourcefulness, and adaptability to special and changing needs of research in one specialized field.
Incumbent will perform a wide variety of standard procedures without detailed technical supervision, in horticulture. They may also modify, vary or adapt standard procedures to meet the needs of research projects, or improve tests that are unsatisfactory, and after studying available literature, analyze and alter conditions under which determinations are made.
The position is a full-time position requiring 40 hours per week, but flexibility is required according to travel schedule and seasonal work schedule. Occasionally it may be required to work during the weekend or on holidays. The position requires frequent travel to nursery and greenhouse operations in southern California and infrequent but regular travel to Central Valley, Ventura/Santa Barbara, Watsonville/Salinas/Gilroy, Sacramento. The expected frequency of travel for data collection and organizing trainings is 2 days per week.
This position is a career appointment that is 100% fixed, with grant funding available through 10/01/2026.
Pay Scale: $28.88/hour to $36.62/hour
Job Posting Close Date:
This job is open until filled. The first application review date will be 11/15/2024.
Key Responsibilities:
10%
Reporting and Writing
Summarize research findings for use in articles (popular press, newsletter and journal) using MS Office suite programs and statistical programs.
Assist in preparation of grant proposals and in summarizing literature and data needed for funding group reports and assist in writing publications and peer reviewed publications in scientific journals.
Prepare graphical summaries, using Microsoft Excel, that will be used to demonstrate the discovered data in publications.
Review studies, literature, attend workshops, seminars, training.
Prepare travel reports in accordance with University policies.
15%
Data Preparation
Collect data and prepare initial reports. Modify, vary or adapt standard procedures to meet the needs of the research project.
Convert raw data into testable value; conduct basic statistical analysis. Ensure that there is the necessary information to evaluate each trial.
Generate summary and overview reports of program activities as needed. This includes educational event and field demonstration evaluations and monthly, quarterly, and annual reporting as needed.
Manage survey data from training events.
40%
Outreach
Coordinate and collaborate with federal, state, county, and local agencies and community-based organizations on the delivery of programs to support program functional area.
Produce educational videos which may include filming and editing
Delivers trainings, with guidance and oversight from the Advisors, on the topic of irrigation and water management in English and Spanish for California nursery irrigators and production managers
Organizes all aspect of trainings including booking travel and coordinating with cooperators.
35%
Field Work/Research
In consultation with the supervisor, plan and assist in coordination of project experiments. Ensure that sufficient materials are available to provide required safety training and documentation to assure safe work environment.
Under direction of the Advisors, set up experiments and collect data at various nurseries throughout Southern California regarding irrigation and pest management
Requirements:
Demonstrated scientific/research experience or formal education in horticulture, agriculture, or related field.
Experience with research and/or teaching, training, or workshops.
Experience with scientific field studies including data collection, data management and data entry.
Scientific knowledge and skill to make technical determinations and/or observations.
Ability to deliver effective presentations in conjunction with Advisor coaching and guidance.
Ability to set up scientific experiments and collect data with Advisor supervision.
Knowledge of the principles of horticulture, which may include: irrigation and water quality, pest, disease, and fertilization management.
Demonstrated ability to develop and outreach to community partners.
Demonstrated experience with computers, software, and social media for the development and delivery of newsletters, presentations, and other educational materials. Experience using Microsoft Office.
Excellent oral and written communication skills.
Bilingual Spanish speaking, reading, and writing.
Preferred Skills:
Experience with data compilation in order to produce reports.
Special Conditions of Employment:
Ability to work a flexible work schedule including early mornings, evenings, and weekends and holidays as needed to meet project needs.
Travel, including travel outside of normal business hours may be requested.
Must possess valid California Driver's License to drive a County or University vehicle. Ability and means to travel on a flexible schedule as needed, proof of liability damage insurance on vehicle used is required. Reimbursement of job-related travel will be reimbursed according to University policies.
The University reserves the right to make employment contingent upon successful completion of the background check. This is a designated position requiring a background check and may require fingerprinting due to the nature of the job responsibilities. UC ANR does hire people with conviction histories and reviews information received in the context of the job responsibilities.
As of January 1, 2014, ANR is a smoke- and tobacco-free environment in which smoking, the use of smokeless tobacco products, and the use of unregulated nicotine products (e-cigarettes), is strictly prohibited.
To apply, please visit: https://careerspub.universityofcalifornia.edu/psc/ucanr/EMPLOYEE/HRMS/c/HRS_HRAM_FL.HRS_CG_SEARCH_FL.GBL?Page=HRS_APP_JBPST_FL&JobOpeningId=74113&PostingSeq=1&SiteId=17&language Cd=ENG&FOCUS=Applicant
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Associate Scientist- Cell culture
Research Scientist Job 22 miles from Santa Monica
Top 3 Must Have Skill Sets:
Must have:
Western Blots
Cell culture
Transient transfection
Nice to have: Assay development experience, small molecule screening.
Job Details:
Basic Qualifications: Master's degree or Bachelor's degree and 2-3 years of relevant scientific experience.
Responsibilities include:
1) Follows established experimental design and protocols, as well as routine tasks and studies, to obtain reproducible and reliable results under supervision.
2) Plan, monitor or conduct experiments, analyze and record experiments and data, collaborate with group members, and communicate and present data to the team.
3) Effectively trouble-shoots equipment and experimental difficulties ? Contributes to internal/external reports, papers, presentations, regulatory documents,
4) Skilled and/or knowledgeable in the use of standard laboratory equipment
5) Participates in department-wide support efforts such as safety, data recording and centralizing by ELN
Preferred Qualifications:
• Skills: degree in Biology, Biochemistry; experience in a Biopharmaceutical working environment
• Prior experience with biochemical, biophysical, molecular and cellular techniques including basic cell culturing, transient transfection and stable cell lines generation
• Experience with small molecule drug screening campaigns
• Excellent organizational, interpersonal and communication skills
• Flexibility to work in teams to achieve changing project goals and meet timelines
• Strong data analysis, interpret complex data sets and critical thinking skills
Founding Head of AI Products
Research Scientist Job 5 miles from Santa Monica
Clear Skies is incubating a stealth venture that uses an AI-powered platform to serve major stakeholders in private equity. We operate at the intersection of finance/AI to optimize deal flow, automate decisioning, and integrate networks into a seamless customer journey. Our team is composed of seasoned professionals from private equity, financial advisory, human capital, and AI engineering.
We are seeking a Founding Head of AI Products to spearhead the development of AI-driven solutions that redefine how investments are sourced, evaluated, and executed. You will define the product and lead AI initiatives to solve real-world problems in a multi-billion-dollar industry.
Key Responsibilities:
Product Strategy
Execute AI product strategies for market fit and business impact.
Analyze customer needs and competitive landscape to uncover new product opportunities.
Build business cases with market analysis, ROI projections, and scalability assessments.
AI Product Development
Define features and workflows to gather customer feedback and iterate on MVP development.
Build AI-powered engines to transform large-scale unstructured data into actionable intelligence.
Implement NLP techniques for semantic search and keyword matching from unstructured data.
Utilize embedding models for vector-based search and context understanding.
Workflow Automation
Establish scalable AWS-based infrastructure and data pipelines.
Develop automated communications, scheduling, and self-service AI tools.
Implement best practices for AI model versioning, monitoring, and optimization.
Leadership & Collaboration
Lead and mentor AI and product teams, promoting innovation and learning.
Collaborate with business leaders to align AI strategies with goals.
Define and track KPIs to measure product success and guide development.
Key Qualifications:
10+ years in product leadership with focus on AI/ML platforms and generative AI technologies.
Expertise in AI/ML frameworks (TensorFlow, PyTorch, etc.) and cloud infrastructure.
Experience in financial services or private equity is a plus.
Application Process: Interested candidates are invited to submit their CV and cover letter detailing relevant experience and qualifications to ***************************.
About Clear Skies: Clear Skies is a private equity investment firm that acquires middle-market businesses. We partner with management teams to drive growth and value through our global networks.
Research Associate - In Vivo
Research Scientist Job 5 miles from Santa Monica
Partnered with a growing biotech startup dedicated to CNS drug delivery. As a Research Associate - In Vivo, you will play a crucial role in preclinical research and early drug development, assessing therapeutic candidates in animal models.
Key Responsibilities
Design and execute in vivo studies using rodent or other mammalian models.
Handle and process blood and tissue samples for biochemical and histological assays.
Collaborate with cross-functional teams to advance preclinical studies.
Maintain laboratory equipment, generate documentation, and assist in data analysis.
Present findings to multidisciplinary discovery teams.
Adapt to evolving research needs and support various lab tasks as required.
Basic Qualifications
B.S. or M.S. in Life Sciences (Biology, Neuroscience, Pharmacology, or related field).
Strong understanding of CNS disease biology.
Hands-on experience with rodent or mammalian animal models.
Skilled in tissue processing and sample handling with attention to precision.
Familiarity with biochemical/histological analysis techniques and standard lab equipment.
Excellent communication, multitasking, and problem-solving skills.
Preferred Qualifications
Experience with plate-based assays (e.g., ELISA, RT-qPCR).
Knowledge of biologics delivery (antibody, oligonucleotide, peptide) in in vivo studies.
Proficiency in animal handling techniques (behavioral experiments, perfusion) and tissue processing (sectioning, imaging).
Commitment to a two-year tenure for team consistency and growth.
Bioinformatics Scientist
Research Scientist Job 47 miles from Santa Monica
About Burning Rock Dx.:
Burning Rock Dx. (NASDAQ:BNR) was foundedin 2014, and it is a leading innovator in next-generation sequencing (NGS) technologies, dedicated to advancing precision medicine, genomics research, and clinical diagnostics. We collaborate with global partners to deliver cutting-edge solutions for complex biological challenges.
About the Role:
We‘re seeking a highly skilled and motivated Clinical Bioinformatics Scientist to join our CAP-accredited molecular oncology laboratory. The candidate will play a crucial role in analyzing and interpreting Next-Generation Sequencing (NGS) data for cancer diagnostics, ensuring compliance with CLIA/CAP guidelines, and contributing to the development of robust bioinformatics pipelines for somatic and germline variant analysis.
Key Responsibilities:
Analyze and interpret NGS data for molecular oncology applications, including somatic and germline variant calling, copy number alterations, structural variations, and tumor mutational burden (TMB)/microsatellite instability (MSI) analysis.
Develop, optimize, and maintain bioinformatics pipelines for clinical NGS testing, ensuring compliance with CAP, CLIA, and FDA regulatory requirements.
Perform variant annotation, curation, and classification using public and proprietary databases (e.g., ClinVar, COSMIC, gnom AD, OncoKB).
Support quality control (QC) and quality assurance (QA) activities by identifying and troubleshooting technical and computational issues.
Collaborate with molecular pathologists, clinical scientists, and laboratory personnel to ensure accurate variant interpretation and reporting.
Stay up to date with emerging bioinformatics tools, guidelines, and best practices for NGS-based oncology testing.
Assist in validation and verification of new assays, software updates, and enhancements to bioinformatics workflows.
Participate in CAP/CLIA audits, proficiency testing, and regulatory documentation.
Maintain and develop Laboratory Information Management Systems (LIMS) to support efficient clinical sample tracking, data management, and workflow automation.
Work closely with laboratory staff to ensure seamless LIMS integration with NGS pipelines and other bioinformatics tools.
Qualifications:
PhD in Bioinformatics, Computational Biology, Genomics, Molecular Biology, or a related field, OR MS with at least 3 years of relevant clinical experience.
Strong experience with NGS data analysis in a clinical setting, preferably in molecular oncology.
Proficiency in Python, R, Perl, Bash, and Linux-based environments for bioinformatics workflows.
Familiarity with NGS analysis tools such as GATK, SAMtools, BCFtools, VarDict, Mutect2, Annovar, VEP, and other variant callers/annotators.
Experience working with NGS assay validation, quality control metrics, and regulatory compliance (CAP/CLIA/FDA guidelines).
Strong knowledge of human genetics, cancer genomics, and clinical variant interpretation (ACMG/AMP/ASCO guidelines).
Ability to work in a collaborative, fast-paced clinical laboratory environment with strong analytical and problem-solving skills.
Nice to Have:
Prior experience working in a CAP/CLIA-certified clinical laboratory.
Knowledge of cloud-based bioinformatics workflows (e.g., AWS, Terra, DNAnexus).Experience with database management, pipeline automation, and high-performance computing (HPC) environments.
Understanding of laboratory information management systems (LIMS).
Prior involvement in NGS assay development, validation, or FDA submission processes.
Benefits & Perks:
Competitive salary and performance-based bonuses
Comprehensive healthcare, dental, and vision insurance
401(k) retirement plan with company matching
Paid time off and flexible work arrangements
Professional development and conference opportunities
Join us in advancing precision oncology through cutting-edge clinical bioinformatics.
Equal Opportunity Statement:
It is the policy of Burning Rock Dx. LLC to provide equal employment and advancement opportunities to all colleagues and applicants for employment without regard to race, color, ethnicity, religion, gender, pregnancy/childbirth, age, national origin, sexual orientation, gender identity or expression, disability or perceived disability, genetic information, citizenship, veteran or military status or a person's relationship or association with a protected veteran, including spouses and other family members, marital or domestic partner status, or any other category protected by federal, state and/or local laws.
As an equal opportunity employer, Burning Rock Dx LLC is committed to a diverse workforce.
Machine Learning Researcher
Research Scientist Job 47 miles from Santa Monica
We're seeking a sharp, highly analytical individual to take ownership of advanced forecasting and optimization efforts in a unique, energy-focused environment. This role is heavily centered on time series modeling and algorithm design. You'll be building models that directly inform the real-time operation of large-scale systems-not constructing pipelines, managing infrastructure, or deploying models in production environments.
Your focus will be on creating accurate, adaptable forecasting tools and optimization logic. We're specifically looking for someone with deep expertise in time series forecasting and a passion for applying modeling techniques to complex, data-rich problems.
This is not a fit for candidates whose strengths are in data engineering, MLOps, or infrastructure.
In This Role, You'll:
Collaborate closely with cross-functional teams to ensure your models align with operational and business objectives.
Create optimization routines to drive intelligent control strategies for energy storage and load scheduling.
Incorporate new and external data sources to strengthen forecasting reliability.
Keep up with recent advancements in forecasting, ML, and algorithmic optimization to inform your work.
Work with diverse datasets to continuously improve model accuracy and responsiveness.
Write clean, maintainable, and efficient Python code focused on modeling and analytics.
Develop and refine time series forecasting models for key metrics such as energy pricing, datacenter load, and renewable generation.
Who We're Looking For:
Strong communication and collaboration skills.
Masters or PhD in Mathematics, Machine Learning, Statistics, or a related quantitative field.
Comfortable working independently on modeling tasks, without the need to build or maintain data pipelines or infrastructure.
Background in applied math, machine learning, statistics, or related fields.
Strong understanding of model validation, backtesting, and performance metrics specific to forecasting.
Excellent problem-solving skills and the ability to translate messy real-world data into clear modeling approaches.
Proficiency in Python and ML libraries like PyTorch or TensorFlow.
Interest in energy systems, sustainability, or large-scale resource optimization is a plus.
Extensive experience with time series modeling techniques (ARIMA, Prophet, RNNs, LSTMs, Transformers, etc.).
Senior Research Associate In Vivo
Research Scientist Job 22 miles from Santa Monica
AcuraStem is a patient-based biotechnology company pioneering the development of treatments for amyotrophic lateral sclerosis (ALS), Frontotemporal dementia (FTD), and additional neurodegenerative diseases. We are a purpose-driven company on a mission to get our promising treatments into patients' hands as quickly as possible.
AcuraStem's best-in-class disease modeling platform, iNeuroRx , is the gold standard for discovering novel, effective, and broadly-acting treatments. The AcuraStem team's extensive expertise in ASO technology is accelerating the advancement of treatments to the clinic.
At AcuraStem, we know that empowered and supported colleagues strengthen our commitment and significantly enhance our collective mission. We are committed to scientific excellence, impactful results, persistence, attention to detail, teamwork, sound decision-making, and continuous learning.
We are seeking a highly skilled and well-organized Senior Research Associate to contribute to our research programs and drive scientific progress. The Senior Research Associate will work closely with AcuraStem scientists, executing and refining experimental protocols with precision. The ideal candidate will have experience handling rodents and be adept at following detailed protocols meticulously while also demonstrating the ability to propose improvements when necessary.
Responsibilities:
Design, execute and manage in vivo experiments assessing the efficacy and safety of test agents in various rodent models.
Perform a range of in vivo techniques, including rodent handling, various routes of compound administration (IV, ICV, IT), tissue collection, and behavioral assessments.
Manage mouse colonies and perform breeding, weaning, and genotyping.
Conduct various laboratory assays, including immunohistochemistry, microscopy, and biochemistry/molecular biology.
Analyze and interpret experimental data, and prepare scientific documents including study reports, protocols, and other related materials for presentations, regulatory submissions and publications.
Maintain accurate records of experimental data and protocols in accordance with AcuraStem guidelines.
Collaborate effectively with internal/external resources to schedule and execute tasks independently with minimal training/guidance from manager.
Independently conducts multiple complex experiments and provides technical guidance and problem solving related to methods, procedures and processes, and obtain optimum solutions.
Provide technical guidance and problem-solving related to methods, procedures, and processes to the work group.
Mentor and train junior lab members, promoting a positive and collaborative research environment.
Desired Skills and Experience:
Minimum 6+ years of hands-on experience conducting in vivo research with mice or rats.
B.S. in Biology, Neuroscience, Bioengineering, or a related discipline, with 4+ years of industry experience or 6+ years of academic research experience.
Strong verbal and written communication skills for effective collaboration and documentation.
Strong organizational and analytical skills to manage multiple projects simultaneously.
Proven ability to work effectively both independently and as part of a team.
Knowledge of and adherence to Environmental Health & Safety (EH&S) procedures.
Additional Information:
Scheduling Flexibility: Availability for late evening, weekend, and holiday work as needed to support animal welfare needs.
Travel Requirement: Frequent travel (>50%) to various AcuraStem laboratory sites in Los Angeles.
Work Authorization: Candidate must be currently in the USA and authorized to work immediately.
Compensation/Benefits:
The salary range for this position is $82,000 - $115,000 with actual compensation determined by factors such as experience, qualifications, location, and other role-specific requirements.
AcuraStem offers a comprehensive and competitive benefits package tailored to attract top talent. All regular-status employees receive compensation, performance-based bonuses, equity, and extensive benefits, including health, dental, vision, life, and disability insurance. AcuraStem also provides paid time off, annual company holidays, 401K matching, and bi-weekly lunch for onsite staff.
Diversity, Inclusion, and Recruitment Practices at AcuraStem:
Applicants must be authorized to work in the United States. AcuraStem is an equal-opportunity employer and values diversity and inclusion throughout the hiring process. Employment decisions are made based on relevant qualifications, experience, and business needs, without regard to race, color, religion, sex, gender identity, sexual orientation, age, marital status, national origin, disability, veteran status, or any other protected characteristic.
AcuraStem's commitment to diversity and inclusion extends to all areas of employment, including hiring, compensation, performance evaluations, promotions, training, and career development. We strive to provide a supportive and inclusive workplace, free from discrimination or harassment.
For staffing inquiries, AcuraStem's Human Resources team manages all recruitment activities directly. We ask that external recruiters avoid contacting hiring managers or submitting candidates without prior authorization, as unsolicited resumes will not establish any contractual relationship with AcuraStem.
Qualified candidates, please submit your CV/resume to ******************
Principal Applied AI Scientist
Research Scientist Job 5 miles from Santa Monica
Gusto is a modern, online people platform that helps small businesses take care of their teams. On top of full-service payroll, Gusto offers health insurance, 401(k)s, expert HR, and team management tools. Today, Gusto offices in Denver, San Francisco, and New York serve more than 400,000 businesses nationwide.
Our mission is to create a world where work empowers a better life, and it starts right here at Gusto. That's why we're committed to building a collaborative and inclusive workplace, both physically and virtually.
Gusto is looking for a Principal Applied AI Scientist to join our AI team and build out our Generative AI capabilities.
About the Role:
We're looking to accelerate AI investments across the business to solve customer pain points, and are growing our Applied AI team. You'll be a part of the core group of experts exploring big, innovative bets, quickly prototyping solutions and shipping to customers. You're also responsible for quickly iterating on improvements and eventually scaling to production-grade AI applications. You'll be working alongside a multidisciplinary group of Product Engineers, PMs, and Design.
In this role, you'll be responsible for designing, building, evaluating, and shipping products that use proprietary and open source LLMs. You'll be responsible for all aspects of the AI development lifecycle: framing the problem, designing the system, making decisions on frameworks, building, evaluation, and deploying. As an Applied AI Scientist, you'll own the customer impact end-to-end.
Here's what you'll do day-to-day:
Design, develop and deploy innovative AI solutions
Experiment with multi-agent frameworks to build autonomous systems
Improve LLMs through pre-training, fine-tuning, and RLHF
Build evaluation for LLMs and LLM based products, and assess best methods required to build LLMs suited for purpose
Collaborate with the engineering team to determine technical requirements and SLAs for API-enabled services
Research novel AI techniques and strategies that create magical customer experiences
Here's what we're looking for:
8+ years experience designing, evaluating, and productionizing AI applications.
Experience with Agentic AI frameworks (LangGraph and Llama-Index) and experience building, deploying and maintaining LLM-based applications in production are essential
Demonstrated expertise in writing production-level Python code
Proven ability to design and prototype AI solutions quickly
Experience working on multi-agent AI systems to automate end to end workflows
Our cash compensation amount for this role is targeted at $191,000-$237,000/year in Denver, Chicago, and Atlanta, $208,000-$258,000/year in Los Angeles and Seattle, and $225,000-$279,000/year for San Francisco and New York. Final offer amounts are determined by multiple factors including candidate experience and expertise and may vary from the amounts listed above.
Gusto has physical office spaces in Denver, San Francisco, and New York City. Employees who are based in those locations will be expected to work from the office on designated days approximately 2-3 days per week (or more depending on role).
Our customers come from all walks of life and so do we. We hire great people from a wide variety of backgrounds, not just because it's the right thing to do, but because it makes our company stronger. If you share our values and our enthusiasm for small businesses, you will find a home at Gusto.
Gusto is proud to be an equal opportunity employer. We do not discriminate in hiring or any employment decision based on race, color, religion, national origin, age, sex (including pregnancy, childbirth, or related medical conditions), marital status, ancestry, physical or mental disability, genetic information, veteran status, gender identity or expression, sexual orientation, or other applicable legally protected characteristic.
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Principal Scientist - Cardiometabolic Disorders
Research Scientist Job 22 miles from Santa Monica
Apply remote type On Site locations US - California - Thousand Oaks time type Full time posted on Posted 2 Days Ago job requisition id R-203821
Career Category
Research
Job DescriptionJoin Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
We are building upon our solid Cardiovascular foundation and long-term dedication to patients by developing a whole new class of novel molecules. We are seeking a dedicated and highly motivated Principal Scientist to become a member of the Department of Cardiometabolic Disorders within Amgen Research located in Thousand Oaks, CA. In this vital and exciting role you will be an ideator and drug hunter and are expected to conduct biology research and identify therapeutic targets in cardiometabolic disease that are tractable and offer the opportunity of delivering disease-modifying potential in patients. The proposal and advancement of a drug discovery program will be based on a sound and compelling scientific rationale that may include validation from human genetics and/or clinical studies. Critical thinking, ingenuity, the ability to design and conduct mechanistic studies and deep biology, technical proficiency, excellent communication skills, integrity and the ability to work in a multi-disciplinary environment will be critical toward advancing programs in the cardiometabolic pipeline. You will initially work at the bench conducting in vivo and/or in vitro preclinical studies with a focus on PAH, vascular disease and/or heart failure. Over time, you will also demonstrate strong leadership skills and the ability to manage a team of scientists conducting drug discovery research.
As part of the team, the candidate may also support other new and existing drug discovery programs in the department to help advance the best assets in the Cardiometabolic Disorders portfolio.
Conceptualizing and proposing therapeutic targets for the treatment of cardiometabolic disease
Designing and performing in vitro and cell-based experiments
Independently performing data analysis and interpreting results
Communicating scientific results through written and oral presentations
Collaborating with teams from other functions in the company to advance our programs
Documenting work through written protocols, electronic laboratory notebooks and study reports.
Advising colleagues in areas of expertise
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.
Basic Qualifications:
Doctorate degree and 2 years of scientific experience
Or
Master's degree and 5 years of scientific experience
Or
Bachelor's degree and 7 years of scientific experience
Preferred Qualifications:
PhD with postdoctoral experience in cardiometabolic disease (industry experience is strongly preferred)
Strong target ideation capabilities and critical thinking to enable discovery of innovative medicines for patients
Exceptional in vivo and/or in vitro pharmacology skills and capability to independently design, implement and analyze studies with proper controls and generate reproducible high-quality data
Technical mastery of general molecular biology, biochemical, and cell-signaling techniques including immunoblotting, immunocytochemistry, RT-qPCR, immunoprecipitation, and ELISA
Basic knowledge of statistical methods applied in a consistent and rigorous manner to all data sets generated
Excellent written and oral communication skills and interpersonal skills that enable effective team interactions and communication of key data to all key stakeholders
A strong ability to collaborate cross-functionally in a multidisciplinary environment is critical
Capability to deliver high quality manuscripts, posters and presentations for internal and external peer-reviewed publication and conference attendance.
Understanding of human genetics and genomic data mining for target identification are a plus.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Salary Range
135,729.00 USD - 168,454.00 USD
About Us
Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.
Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.
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Principal Scientist
Research Scientist Job 22 miles from Santa Monica
Join Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas: Oncology, Inflammation, General Medicine, and Rare Disease, we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Principal ScientistWhat you will do
Let's do this. Let's change the world. We are seeking a highly motivated Principal Scientist to join the Structural Biology group at our site in Thousand Oaks, CA. The Structural Biology group provides comprehensive molecular insights and structure-based design for drug-target assessment, mechanism of action, protein-protein and protein-ligand interactions, as well as protein engineering to facilitate drug discovery across various therapeutic areas. The Principal Scientist will be responsible for structure determination of target molecules using X-ray crystallography and cryo-electron microscopy (cryo-EM).
Interact directly with small molecule scientists including computational scientists, medicinal chemists, and protein engineers.
Apply knowledge to new areas of study, with strong interpersonal and communication skills to thrive in a highly collaborative environment.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a leader with these qualifications.
Basic Qualifications:
Ph.D. with a deep understanding of structural biology and general biochemistry and biophysics.
Significant postdoctoral AND industrial (pharma/biotech) research experience, in large macromolecular complex structure determination. Knowledge of state-of-the-art protein structural biology techniques including all aspects of construct design, expression, purification, characterization, structure determination, and analysis.
Proven expertise on protein crystallography AND cryo-EM single particle analysis, to determine atomic resolution structures.
Experience with ubiquitin-proteasome system for protein degradation is a plus.
Excellent presentation skills (written and oral) for effective team-based communication of results.
Ability to work independently and effectively within timelines and to collaborate in a multidisciplinary environment.
Willingness to take on new/unfamiliar responsibilities to help the team.
Skills in managing multiple projects and capability to prioritize.
Preferred Qualifications:
Experience with other protein biochemical and/or biophysical characterization of protein complexes.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
Stock-based long-term incentives.
Award-winning time-off plans.
Flexible work models, including remote and hybrid work arrangements, where possible.
Apply now
for a career that defies imagination.
Objects in your future are closer than they appear. Join us.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Protein Scientist (Molecular Biology)
Research Scientist Job 22 miles from Santa Monica
Who we are: 20bloc, Inc. (*************** is an early-stage biopharma company creating breakthrough protein-based drugs to save lives. We are developing a safe and effective hemoglobin-based oxygen carrier for first response, organ preservation and oxygen therapy. We value and encourage innovations through robust information exchange, hard work, and team interaction. We are collaborative. We are intellectual. We are hands-on.
Job Title: Protein Scientist (Molecular Biology)
Position Overview: We are seeking an experienced Protein Scientist with a background in molecular biology and hands-on experience in genetic engineering and yeast-based expression systems.
Key responsibilities:
Design, construct and optimize innovative recombinant expression systems with yeast such as Pichia/ komagataella phaffii and Saccharomyces strains to produce high-level expression of target proteins.
Characterize genetic and phenotypic engineered strains, and analyze expression levels, post-translational modifications, and product quality.
Collaborate with fermentation scientists to integrate molecular biology work with bioprocess development and production scale-up.
Identify, qualify and manage CROs and coordinate with partners.
Write detailed experimental records, scientific reports and presentations.
Requirements:
PhD in Molecular Biology, Biotechnology, Genetics, Biochemistry, or a related field
2+ years of industry experience working directly on genetic engineering.
Track record in molecular cloning, gene editing, vector design, transformation, strain screening, and optimization of yeast expression systems.
Proficiency in analytical methods to assess protein expression and quality, such as ELISA, flow cytometry, or glycan analysis.
Strong planning and problem-solving skills and ability to work both independently and collaboratively in a multidisciplinary team.
Excellent communication skills, with a proven ability to document research findings and present and interpret complex data and findings concisely and clearly.
This is an excellent opportunity for a motivated individual to grow and excel in an early-stage biopharma company to develop a groundbreaking drug that could make an impact to the life of many. This is a full time position on-site in Thousand Oaks, CA.
20bloc is an equal opportunity employer. We offer a comprehensive benefits package which includes:
Medical, dental and vision plans
120 hours paid time off (PTO)
12 paid holidays annually
401(k) U.S. retirement savings plan
Employee assistance program
Scientist
Research Scientist Job 47 miles from Santa Monica
Akkodis is seeking a Scientist I for a contract to hire, onsite position with a client in Irvine, CA.
/ No Corp-to-Corp; No C2C; No Referrals from C2C accepted
Rate Range: $25.00/hour to $28.00/hour; The rate may be negotiable based on experience, education, geographic location, and other factors.
Job Title: Scientist I - Chemistry/Microbiology
Location: Irvine, California
Department: Advanced Research & Development
Position Summary:
We are seeking a highly motivated and detail-oriented Scientist I to join our Advanced Research & Development team. The successful candidate will support both routine and exploratory testing, method development, and process improvement initiatives. This hands-on laboratory role involves data collection, analysis, and collaboration with cross-functional teams to drive innovation and support the development of next-generation products.
________________________________________
Key Responsibilities:
Under supervision and in accordance with applicable regulations (e.g., FDA, ISO) and company
policies and procedures, the Scientist I will:
•Conduct experiments to support the development and evaluation of new technologies for potential products, including biological and chemical studies involving materials, medical devices, and associated cleaning agents, disinfectants, sterilants, and processing technologies.
•Execute research studies by following prepared protocols and experimental designs to support product development across feasibility, verification, and validation phases.
•Perform data analysis, organize results, and prepare basic reports and summaries.
•Prepare microbiology media/fluids and sterilize glassware and laboratory supplies as needed.
•Participate in routine laboratory maintenance, instrument calibration, and inventory management.
•Collaborate with internal stakeholders to meet project timelines and deliverables.
•Clearly and effectively communicate experimental progress and testing outcomes to team members.
•Support general lab functions and perform other duties as assigned.
•Contribute to a collaborative and high-performing team environment.
________________________________________
Qualifications:
•Bachelor's degree in Chemistry, Microbiology, Biochemistry, or a related scientific discipline is required.
•At least 2 years of relevant laboratory experience in academic, research, or industrial settings is preferred.
•Familiarity with standard analytical and/or microbiological techniques and instrumentation is required.
•Strong attention to detail, organizational skills, and commitment to quality is required.
•Ability to work independently as well as collaboratively within a team is required.
•Excellent communication, documentation, and critical thinking skills are required.
________________________________________
Work Environment & Physical Requirements:
•Ability to lift and carry a minimum of 25 lbs.
•Position requires physical activity including:
o Up to 80% standing
o Up to 80% walking
o Up to 50% sitting
o Up to 10% kneeling
•Frequent repetitive hand motions required, including pipetting, twisting, simple grasping, fine manipulation, and computer use.
•Appropriate use of personal protective equipment (PPE) is required at all times.
If you are interested in this role, then please click APPLY NOW. For other opportunities available at Akkodis go to ****************
Equal Opportunity Employer/Veterans/Disabled
Benefit offerings available for our associates include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, an EAP program, commuter benefits, and a 401K plan. Our benefit offerings provide employees the flexibility to choose the type of coverage that meets their individual needs. In addition, our associates may be eligible for paid leave including Paid Sick Leave or any other paid leave required by Federal, State, or local law, as well as Holiday pay where applicable. Disclaimer: These benefit offerings do not apply to client-recruited jobs and jobs that are direct hires to a client.
To read our Candidate Privacy Information Statement, which explains how we will use your information, please visit ******************************************
The Company will consider qualified applicants with arrest and conviction records in accordance with federal, state, and local laws and/or security clearance requirements, including, as applicable:
· The California Fair Chance Act
· Los Angeles City Fair Chance Ordinance
· Los Angeles County Fair Chance Ordinance for Employers
· San Francisco Fair Chance Ordinance
Associate Scientist
Research Scientist Job 22 miles from Santa Monica
Fully Onsite - Regular working hours.
Job Details:
Basic Qualifications: Master's degree or Bachelor's degree and 2-3 years of relevant scientific experience.
Responsibilities include:
1) Follows established experimental design and protocols, as well as routine tasks and studies, to obtain reproducible and reliable results under supervision.
2) Plan, monitor or conduct experiments, analyze and record experiments and data, collaborate with group members, and communicate and present data to the team.
3) Effectively trouble-shoots equipment and experimental difficulties ? Contributes to internal/external reports, papers, presentations, regulatory documents,
4) Skilled and/or knowledgeable in the use of standard laboratory equipment
5) Participates in department-wide support efforts such as safety, data recording and centralizing by ELN
Preferred Qualifications:
• Skills: degree in Biology, Biochemistry; experience in a Biopharmaceutical working environment
• Prior experience with biochemical, biophysical, molecular and cellular techniques including basic cell culturing, transient transfection and stable cell lines generation
• Experience with small molecule drug screening campaigns
• Excellent organizational, interpersonal and communication skills
• Flexibility to work in teams to achieve changing project goals and meet timelines
• Strong data analysis, interpret complex data sets and critical thinking skills
Azad Mishra
O ************** Ext 70889
E **********************
Associate Hardware Scientist (Mass Spec - Ion Traps)
Research Scientist Job 35 miles from Santa Monica
For over 50 years, SCIEX has been developing groundbreaking technologies and solutions in mass spectrometry and capillary electrophoresis. Our products enable our customers to quickly respond to environmental hazards, better understand biomarkers relevant to disease, improve patient care in the clinic, bring relevant drugs to market faster and keep food healthier and safer. At SCIEX, you'll find a rewarding role that amplifies your impact on the world and helps you realize life's potential.
SCIEX is one of 10 Life Sciences companies of Danaher. Together, we accelerate the discovery, development and delivery of solutions that safeguard and improve human health.
Learn about the Danaher Business System which makes everything possible
Are you ready for the next step in your mass spectrometry career? The Associate Hardware Research Scientist (Mass Spectrometry- Ion Traps) is responsible for driving innovation around ion traps and mass analyzers.
This position is part of the Hardware Research Department and will be located in Concord, Ontario.
In this role, you will have the opportunity to:
Defines and tests novel ion trap hardware to enable improved performance for customer workflows
Performs different methodologies to verify or validate different aspects of hardware/software under the mentorship of more senior scientists
Drives innovation by generating novel ideas to advance scientific technology
Identifies and implements opportunities for product improvement within a defined research area
Contributes to on-time delivery of different research projects and translates development or scientific risks into a tangible research plan
The essential requirements of the job include:
Higher level Science degree in a related field such as Physics, Chemistry, or similar required (Ph.D. preferred)
Broad background and knowledge of ion movement, mass analyzer technology, ion trap technology and ion trap theory
Proven publication record within the field related to hardware design
Experience with various sample introduction techniques
It would be a plus if you also possess previous experience in:
Understands the link between project goals and company strategy
Ability to work independently
Proven track record of innovation and patent generation preferred
The salary range for this role is $90-$120K CAD. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future.
SCIEX, a Danaher company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it's a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at
Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
For more information, visit .
Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at to request accommodation.
Formulation Scientist
Research Scientist Job 15 miles from Santa Monica
Formulation Scientist- Simply Biotech
Are you looking for a new career opportunity with an exciting biotech company?! Then we've got the right team for you! In this role, you're responsible for the duties listed below.
Immediate opening for a Formulation Scientist with a biotech company in Torrance, CA who possesses:
Bachelor's degree in chemical engineering, chemistry, food science/technology, or similar
2 years' experience in nutritional supplement industry or similar field (working with dietary supplements, pharmaceutical development, etc.)
1+ year experience in granulation techniques, processing, and property characterization
Email resumes to ************************* or call ************
FULL DESCRIPTION
: The Formulation Scientist is responsible for the development of new products, enhancement of existing formulations, and resolution of manufacturing challenges. This role involves evaluating new and alternative raw materials, identifying cost-saving opportunities, and ensuring compliance with regulatory standards. The scientist will formulate powders, tablets, capsules, and nutrient premixes tailored to customer specifications while considering application requirements, shelf life, processing conditions, and stability. Additionally, this position will contribute to ingredient assessments and provide internal blending instructions as needed.
The selected candidate will be responsible for:
Thorough understanding of solid dose product development and manufacturing scale-up.
Operational understanding of wet and dry granulations, tablet presses, encapsulation machines, ribbon blenders, and V-blenders.
Develop and make lab samples of custom dietary supplement blends.
Interpret customer requests into prototypes, such as great-tasting powdered beverages or tablets designed with various properties.
Work with R&D teams, Manufacturing, supply chain, etc. on scale-up and transfer of developed formulations to the plant.
Provide customers with technical support on dietary supplement formulations.
Maintain proper documentation of product development process and results and keep equipment logbooks in accordance with R&D guidelines.
Comply with company procedural guidelines, laboratory procedures, and safety programs.
The selected candidate will also possess:
Bachelor's degree in chemical engineering, chemistry, food science/technology, or similar.
2+ years prior experience in a nutritional supplement industry or similar field.
2+ years working with dietary supplements, pharmaceutical development, or similar.
2+ years' experience in granulation techniques, processing, and property characterization.
Ability to formulate nutraceutical and powdered functional food prototypes based on nutritional targets as well as to consumer sensory acceptance.
Understanding of GMP manufacturing considerations and requirements.
Good interpersonal and presentation skills to share development work within the organization and with customers.
Ability to work in a physically challenging environment: lift 25 pounds and move up to 50 pounds when working with bulk ingredients, operate pilot scale equipment.
Be authorized to work in the United States
Salary Range: $75k-85k/yr
For immediate and confidential consideration, please email your resume to ************************* or call ************. More information can be found at *********************
Transcriptomics Scientist - Wet Lab (mRNA Specialization)
Research Scientist Job 22 miles from Santa Monica
Job Title: Transcriptomics Scientist - Wet Lab (mRNA Specialization)
Type: Contract with potential to turn into full-time
We are looking for an experienced and hands-on scientist to lead and execute mRNA-related wet lab experiments. The ideal candidate will have deep expertise in transcriptome profiling techniques, RNA isolation and quality control, and next-generation sequencing (NGS) library prep, with a particular focus on mRNA biology. This role is heavily experimental and requires a passion for lab work, molecular assay optimization, and data generation.
Key Responsibilities:
Design and execute experiments for transcriptomic profiling, including bulk and targeted mRNA analysis.
Isolate high-quality RNA from a variety of sample types (e.g., tissues, cells, biofluids, extracellular vesicles) and perform quality assessments.
Develop and optimize mRNA-focused protocols for RNA extraction, cDNA synthesis, qPCR, and NGS library preparation.
Maintain and operate equipment such as Agilent Bioanalyzer, Qubit, thermal cyclers, illumina sequencers and nanopore sequencers , and automated liquid handlers.
Interpret experimental results and troubleshoot technical issues in collaboration with cross-functional teams.
Document experimental procedures, protocols, and results in lab notebooks and databases.
Stay up to date on advancements in transcriptomics technologies and incorporate new methodologies as appropriate.
Qualifications:
PhD or MS in Molecular Biology, Biochemistry, Genetics, or related field with 2+ years (PhD) or 4+ years (MS) of hands-on wet lab experience in transcriptomics.
Deep understanding of mRNA biology and transcriptomic workflows (e.g., polyA selection, rRNA depletion).
Strong hands-on experience with RNA isolation, reverse transcription, qPCR, and NGS library prep.
Familiarity with working with human or animal tissue and cell culture samples.
Experience working in a fast-paced, collaborative research environment.
Excellent organizational, communication, and data documentation skills.
Experience with automation platforms or single-cell workflows is a plus but not required.
The Company:
GrittGene Therapeutics is a start-up company at the R&D preclinical stage aimed at the development of treatment for DM, particularly DM2. We are building a diverse team of highly motivated professionals from various fields of science and technology. We are building a diverse, interdisciplinary team of dreamers and doers. We're looking for fellow visionaries hungry for real impact in reimagining every facet of how we cure disease.
Formulation Scientist (Nutraceuticals)
Research Scientist Job 27 miles from Santa Monica
Summary: The R&D Formulator develops and optimizes formulations, conducts testing, and ensures accurate documentation. Supports technology transfer, collaborates cross-functionally, and stays updated on industry trends. Maintains lab safety, mentors staff and participates in management meetings. Evaluates raw materials, improves formulations, and oversees special projects as assigned.
Essential Duties and Responsibilities
Formulation creation (bench mix, formulation sheet, product description sheet, sample measurement, color verification, etc.)
Writes and/or reviews procedures, purchase orders, quotes, and specifications needed to support product development activities
Develops and/or performs all formulation requirements on new formulas
Documents test results, specifications, and final formula procedures in a standard format for inclusion in the master file
Participates in the technology transfer from pilot scale to manufacturing
Communicates, in a timely fashion, all information regarding formulation, project status, raw material research, results, etc. to all appropriate individuals in Purchasing, Sales, Customer Services, and Quality departments
Conducts intellectual searches for technical information through a variety of resources
Keeps abreast of current trends, practices, developments, and regulatory changes, which would impact products, procedures, or formulation
Ensures the maintenance and/or adherence to good laboratory practices and all safety regulations both in laboratory and manufacturing areas
Provides technical knowledge in guiding other assistants/technicians in the R&D Lab
Develops and presents to the R&D Manager or Director, R&D matters requiring his/her decision
Participates in scheduled Management and Sales meetings in the absence of the R&D Manager/Director
Evaluate new and alternative raw materials for functionality and stability
Assist in verification studies as required
Reformulate to improve existing products as needed
Special projects as needed and any other tasks assigned by the R&D Director or Manager.
Qualifications/Education/Experience:
Minimum Bachelor of Science in Chemistry or related field
2+ years' Experience in R&D, Quality Assurance, Quality Control or Manufacturing is required; nutritional, pharmaceutical or biotechnology experience preferred;
Have strong eye for color, finish, and detail
Must have proficient math skills; weights and volumes experience a plus
Excellent communications (verbal/written)
Excellent organizational and multi-tasking skills
Proficient with MS Word, Excel, Teams, and Outlook
Work Environment:
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the duties of this job, the employee is occasionally exposed to work near moving mechanical parts, fumes, or airborne particles and risk of electrical shock. The noise level in the work environment is usually moderate.
Physical Demands:
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Physical demands require sitting for extended periods of time, walking, bending, reaching, carrying, and occasionally lifting and/or moving objects up to 25 pounds. Specific vision abilities required by this job include Close vision, Peripheral vision, and the ability to adjust focus. While performing the duties of this job, the employee is occasionally required to use hands to finger, handle, or feel; reach with hands and arms; climb or balance; stoop, kneel, crouch, or crawl and talk or hear.
Principal Scientist - Safety Pharmacology
Research Scientist Job 22 miles from Santa Monica
Join Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Principal Scientist - Safety PharmacologyWhat you will do
The Translational Safety and Bioanalytical Sciences (TS&BA) function at Amgen is seeking candidates for the position of Principal Scientist to join our Safety Pharmacology Sciences (SP Sci) team based in Thousand Oak, CA. The SP Sci team supports the Amgen portfolio from target identification through clinical development, with an emphasis on developing translational safety strategies to support project teams and various drug modalities. The Principal Scientist will be part of an expert team dedicated to the development of small molecules, oligonucleotides and protein therapeutics in close collaboration with toxicologists, pathologists, and scientists within the organization. In this vital role, you will design and perform in vitro assays for various projects and present the work to cross-functional teams. Additionally, multiple opportunities exist for the new hire to grow their career by leveraging their subject matter expertise to innovate, collaborate with other members of the SP Sci team, and engage with drug discovery project teams.
Responsibilities:
Serve as an in vitro and ex vivo electrophysiologist, supporting investigative activities by employing electrophysiology techniques to assess the impact of test compounds on ion channels, cells, and isolated tissues, such as the isolated perfused heart.
Provide subject matter expertise in developing fit-for-purpose translational safety strategies to address new challenges within the Amgen drug pipeline.
The successful candidate will have an in-depth understanding of ion channel biophysics and pharmacology with proven ability to apply this knowledge in the development and validation of assays related to ion channel and cardiac function.
The candidate will hold subject matter expertise in a particular area which could include use of hi PSC-derived cardiomyocytes for compound screening, dissociated primary cells, or heterologous mammalian cell expression systems, and techniques such as patch clamp, multielectrode array (MEA) recording or calcium imaging.
Experience with artificial intelligence, machine learning, and/or programming would be advantageous.
The candidate should have a results-focused attitude, with a track record of independent critical thinking and scientific achievement in the area of electrophysiology.
The candidate should have strong verbal and written communication skills, be highly motivated, creative and collaborative, with the ability to work in a team environment.
What we expect of you
The dynamic professional we seek is a subject matter expert with these qualifications.
Basic Qualifications:
Doctorate degree PhD OR PharmD OR MD in a relevant scientific discipline (e.g. physiology or pharmacology) and 2 years of electrophysiology experience.
Or
Master's degree and 5 years of electrophysiology experience.
Or
Bachelor's degree and 7 years of electrophysiology experience.
Preferred Qualifications:
Pharmaceutical industry electrophysiology experience.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
Stock-based long-term incentives.
Award-winning time-off plans.
Flexible work models, including remote and hybrid work arrangements, where possible.
Apply now and make a lasting impact with the Amgen team.careers.amgen.com Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Payment Poster & Research Specialists
Research Scientist Job 42 miles from Santa Monica
Payment Poster & Research Specialists (Medical Billing / Collections)
Pride Health is hiring a Payment Poster & Research Specialist for one of its clients in California.
This is a 3-month contract with a possible extension, with competitive pay and benefits.
Location - Costa Mesa, California (92626)
Pay range - $22 - $25 per hour.
Length of assignment - 3 months (With Possible extension)
Shift - Monday-Friday, 1st shift.
Job Summary
The Payment Poster & Research is responsible for posting and reconciliation of all electronic and manual insurance payments and patient payments.
Job Duties
Works directly with internal departments, external business partners (vendors, banks), and Accounting for delivery of service to include, but not limited to, timely and accurate posting of all payments and cash for Client's Hospital Newport Beach, Client's Hospital Irvine, and Client's Orthopedic Institute.
Has expert knowledge of Affinity, Emdeon, Streamline, and MedAssets.
Works efficiently to ensure payments are posted promptly.
Works well under pressure, has attention to detail, can multitask, and has proficient computer and mathematical skills.
Posts batches timely manner according to department guidelines.
Works closely with accounting to ensure AR reporting is accurate and balances daily.
Organizes daily posting logs and submits them to Accounting each day for reconciliation of daily postings.
Works facilities Suspense accounts weekly to identify & transfer funds to appropriate patient account(s).
Conducts payment posting research: Includes identifying posting errors, transferring funds correctly, and documenting on the reconciliation log for reporting to accounting.
Contact payors for additional documentation to identify patient accounts.
Review and work email requests from staff, management, and other departments for payment posting research within the set timeliness guidelines.
Effective interfaces with other organizational departments and project team members.
Works closely with vendors on missing posting files or posting file errors, including unbalanced files.
Pull payment reports from vendor websites as needed for help in posting research and patient account identification.
Participates actively in any training opportunities to enhance knowledge to help Client's patients.
Participates in problem-solving and process improvements.
Meets quality assurance and productivity standards.
Demonstrates knowledge of and effectively uses patient account systems (Affinity, Chart Maxx, MedAssets, and Emdeon).
Able to work with minimal supervision.
Performs other duties as assigned.
Requirements
High school diploma or equivalent required.
2 to 3 years of medical billing and/or collection experience required in a hospital setting.
Analytical, critical thinking, and sound decision-making skills.
Basic skills in Microsoft Office (Word/Excel).
Ability to communicate clearly and professionally.
Strong interpersonal skills.
Ability to problem solve, prioritize, and follow through completely with assigned tasks.
Benefits
Pride Global offers eligible employees comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance, and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, auto, home insurance, pet insurance, and employee discounts with preferred vendors.
Equal Opportunity Employer
As a certified minority-owned business, Pride Global and its affiliates - including Russell Tobin, Pride Health, and Pride Now - are committed to creating a diverse environment and are proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, pregnancy, disability, age, veteran status, or other characteristics.
Associate Production Scientist
Research Scientist Job 15 miles from Santa Monica
"The Associate Production Scientist is responsible for a upscaling R&D small scale work into GMP large scale manufacturing, Oversee production activities of the assigned projects, collect and analyze GMP data, Author and review quality documents such as MBPR, R.A, PPQ protocol, drive yield and process improvement projects, update the customer with the GMP activities, ensuring production processes meet quality standards, or maintaining equipment efficiency]. This role contributes directly to PolyPeptide's commitment to delivering exceptional quality and on-time delivery to our customers."
Key Responsibilities:
List the key tasks and duties for the role. Use action verbs and make each responsibility specific and measurable. Prioritize by importance.
* Review and approve quality and validation documents as the production representative that does not need managers approval (MBPR, CC, SOP, PQE, PPQ related documents, educational certificates etc.)
* Perform Operational assessments.
* Prepare weekly slide deck presentations on project updates to internal and external stakeholders.
* Lead and/or prepare and/or support product investigations using root cause analysis techniques (interviewing, fishbone diagram, 5 whys etc) and summarizing findings in written reports and oral presentations to internal and external stakeholders (QIRM, OOT, OOS, RCI, CAPA/Task)
* Author, prepare and support Deviations, process change controls, CAPA during project execution.
* Prepare Change Control Change Request and list of change document as part of MBPR generation (CC general and for MBPR)
* Draft and review Standard Operating Procedures (QUMAS)
* Conduct Risk Assessment (CRIA, RIA, FMEA)
* Approve quality documents as the production representative that does not need managers approval (MBPR, ARM, CR, SOP, PQE, validation documents, educational certificates etc.)
* Generate detailed Gannt chart of batch schedule.
* BOM generation and Process mapping (soon to include route & formula)
* Provide on-floor and remote 24/7 technical support to Production during project execution (including weekends, grave, and night shifts), e.g. make go/no go decisions on IPC-results regarding process steps or troubleshooting issues.
* Project management of operation activities related to batch preparation/ execution (equipment/ IPC validation, hold time study, etc…)
* Draft, format and improve MBPR template.
* Support technology transfer activities (generation of comparability report, identification of CPPs, review and approve validation PPQ documents, generation of BPR etc).
* Author and review campaign reports.
* Raw material OOS assessment
* Conduct Bottle neck analysis and Gap analysis of unit operations.
* Prepare Process capability analysis.
* Conduct cost analysis and forecasting.
* Liaise with cross functional groups (Production, QA, QC, Development, Project Management, Sale, Regulatory, Supply Chain etc.) to support the planning and execution of manufacturing operations.
* Collaborate with PD to Design small scale experiments to support investigations or process improvement initiatives.
* Lead, mentor and train Operators and team members as part of upstream and downstream process knowledge transfer on MBPR and unit operations.
* Support continuous improvement initiatives.
* Manually Collect, trend, and analyze in process data as part of process monitoring to determine yields and change points.
* Support QA and regulatory with responding to comments by clients on executed BPR and NDA/BLA, submission.
* Support Validation activities during the planning execution of PPQ runs (prepare supporting PPQ document, e.g. equipment calibration and suitability, analytical methods, hold time study, PPQ strategy etc).
* Support regulatory review of documents.
* Process Mapping
* Routes and Formula on AX to be added to our responsibilities
Qualifications:
Education & Experience
* Required Education: Bachelor's degree in chemistry, Biochemistry, Engineering, or a related field.
* Preferred Education: Masters degree preferred, advanced degree or certifications bachelor's degree in chemistry, Biochemistry, Engineering.
* Experience: Minimum 3 years in pharmaceutical manufacturing GMP production or MS&T team, peptide manufacturing experience preferred.
Skills & Competencies
* Technical Skills: Basic understanding about SPPS GMP manufacturing, Proficiency in HPLC systems, cGMP processes, Data analysis (Minitab experience is preferred).
* Soft Skills: Strong problem-solving, collaboration, Microsoft Data analysis (Minitab experience is preferred), Technical writing, and communication skills, and Microsoft office.
Work Environment & Physical Demands:
* Physical Requirements: N/A
* Work Environment: able to adjust priorities based on business need, able to oversee multiple [projects/ processes arranging throughout SPPS manufacturing to product release.
Performance Metrics (KPIs):
* Meet or exceed 90% of on-time MBPR, technical reports, and quality related documents delivery targets.
* Complete all assigned process mapping, route and formulas, & process evaluation.
* This job might be entitled to a customer facing/ updates in a timely manner.
* Completed all related data collection for the GMP projects and perform trending as needed.
Salary: $75k-90k per year
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.