Associate Scientist
Research scientist job in San Diego, CA
Representative responsibilities will include, but not necessarily be limited to, the following:
Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays.
Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations.
Author and review QC analytical SOPs, protocols, and reports as needed
Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports
Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures.
Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated
Skills:
Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products.
Education:
BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience
Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role
Experience in an FDA-regulated environment
Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic
Excellent organizational and communication skills
Experience with JMP statistical software a plus.
AI Machine Learning Scientist
Research scientist job in San Diego, CA
, please email **********************
We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines.
RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions.
The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery.
Duties and Responsibilities:
Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform.
Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery.
Monitor and evaluate the performance of AI/ML models and drug discovery solutions.
Utilize software engineering best practices to develop complex AI applications at scale.
Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML.
Proactively scope and deploy novel computational methods and digital technologies.
Education and/or Experience:
Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field.
Expertise in deep learning and machine learning.
Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow)
Knowledge, Skills, and Abilities:
Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience.
Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods.
Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs).
Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins.
Fluency in scientific programming and tool development with Python, R, or equivalents.
Proficiency in C++ or Java is a plus.
Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications.
Experience with software development good practices, including code versioning, documentation, and testing.
Experience with cloud computing.
Creative, open-minded, and passionate about scientific research.
Demonstrated ability to thrive in a team environment.
Strong interpersonal, collaborative, organizational, and presentation skills.
Understanding of RNA therapeutic modality discovery and development.
No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California.
Supervisory Responsibilities:
This position does not currently have direct reports.
Perks and Benefits:
Generous employer-paid healthcare for Medical, Dental, and Vision.
100% Employer Paid Life, STD and LTD
401(k) Employer Match
Generous Vacation and Sick Leave
13 Holidays
Closed over the Christmas and New Year Holiday Break
Late Stage Oncology Clinical Scientist (Director, Non MD) Multiple Positions
Research scientist job in San Diego, CA
You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within our Late-Stage Oncology portfolio. **Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment.
Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program.
Responsible for scientific oversight, data integrity and quality of the clinical trial(s).
Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy.
Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate.
Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders.
In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s).
Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, **OR**
MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO **OR**
BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO
Clinical Research experience in the phase 2 - 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval
Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance
Experience working on large data sets
Proficiency with Microsoft Office and relevant scientific software
Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations
Experience building partnerships across the company to achieve the needs of the program
**Demonstrates passion for helping patients with cancer and for the science of oncology
Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned
Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities
Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes
Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies
Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes
Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development
Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. Work Location Assignment:** This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week
In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility.
**Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Research Associate I
Research scientist job in San Diego, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
As a Research Associate you will support the development of novel microfluidic platforms. You will be part of a multidisciplinary team solving complex problems, working on integration issues and investigating new research areas. Candidates that are engineering with a foundation in biology are better suited for this role vs. pure biologists.
Hands-on testing, integration and optimization of microfluidic systems including fluidics, hardware, firmware, software, and chemistry/reagents Quickly fabricate and test prototyped microfluidic systems Conduct system level testing, assay testing, image analysis Translate benchtop assays to prototype microfluidic systems Use standard lab instrumentation: fluorescence plate readers, fluorescence microscopes, thermocyclers, bioanalyzers, DNA sequencers, syringe pumps Develop and implement experimental test plans Record and analyze complex data sets Develop creative solutions to troubleshoot issues Willingness to be hands-on Share and record experimental results for an audience with broad technical backgrounds at technical meetings
Qualifications
Skills:
Microfluidics Experience with prototyping microfluidic systems: 3D printers, CO2 laser, laser ablation, profilometry Demonstrated ability to understand and successfully work across multiple disciplines including engineering, biology, and software is highly desired
1-2 years of experience in a clean room
1-2 years of experience in a lab environment with wet biology or chemistry experience
1-2 years of experience in product development is highly desired Experience in a BSL-2 lab is a plus Experience with sequencing, library prep and PCR is highly desired Organized and detail oriented Clear communicator and a team player Multidisciplinary approach to problem solving A desire to be part of face paced dynamic environment
Education and Experience
Undergraduate degree in Mechanical Engineering, Bioengineering, Chemical Engineering, Analytical Chemistry, or Physics
Additional Information
Vishnu Kumar
Technical Recruiter
Artech Information Systems LLC
360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960
Office: *************** | Fax: ************
Research Associate I
Research scientist job in San Diego, CA
Job Title: Research Associate I Duration: 18+ Months Job Description: We are seeking a highly motivated contract Research Associate with strong interpersonal communication skills to conduct in vivo studies in mice in our In-Iivo Pharmacology group at La Jolla to support oncology research.
RESPONSIBILITIES:
• Support in vivo experiments
• Flexible working hours including late shift, weekends and holidays
• Strong interpersonal communication skills and team player.
TECHNICAL SKILLS:
• Proficient in handling mice.
• Proficient in administering compounds via various routes (PO, IV, IP, SC).
• Blood collection (via cheek bleed, RO, intra-cardiac).
• Necropsy, collection of various tissue samples for biomarker analysis.
• Experience with tumor cell subcutaneous implantation in mice and live animal surgery is a plus.
• Proficient in data collection/documentation, either in electronic or hardcopy forms.
Qualifications
What is the minimum education experience required?:
ALAT/ALATg, or BS degree in a life science with minimum 1-2 years of hands on laboratory experience in small animal experimentation.
******
• This position requires flexible working hours: A regular 5 day work week will include and require: late shift and include Sat/Sun and holidays. BID dosing schedules are central to this position.
• Lift animal cages.
• Handle hazardous materials and work in animal facility which will require additional medical testing and/or apparatus fitting for OSHA compliance.
Thank You !
Additional Information
All your information will be kept confidential according to EEO guidelines.
Research Associate
Research scientist job in San Diego, CA
Job Description
Pave Talent is excited to present an incredible opportunity for a Research Associate to join a cutting-edge stem cell research team in San Diego, CA!
R&D Scientist
Research scientist job in San Diego, CA
Job Description
Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation.
The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability.
**This is a hybrid position must onsite at least 3 days a week in San Diego, CA.
Key Responsibilities
Develop and optimize analytical and testing methods to support ingredient characterization and functional performance.
Design and validate finished product specifications related to nutritional and bioactive properties.
Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality.
Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification.
Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones.
Provide scientific input and data to support patent filings and intellectual property development.
Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams.
Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline.
Qualifications
Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field.
5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry.
Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred.
Proven experience collaborating with external laboratories or CROs.
Strong technical writing, data interpretation, and presentation skills.
Ability to manage multiple complex projects in a fast-paced, dynamic environment.
Creative, detail-oriented, and motivated by scientific discovery and product excellence.
This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you.
Compensation: $120,000 - $140,000plus benefits
If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose.
Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
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R&D Scientist
Research scientist job in Carlsbad, CA
R&D Scientist - NGS Technology and Applications
title depends on qualification and experience)
Universal Sequencing Technology (UST) Corporation (universalsequencing.com), a leading NGS technology company engaged in long range/long read sequencing technology and single cell sequencing technology development, headquartered in greater Boston with a branch in San Diego, is looking for an outstanding R&D scientist to join our NGS technology and product development team in San Diego. This position is a unique opportunity to work on a cutting edge NGS library technology which enables many previously unachievable applications, especially in the clinical space.
This person will work closely with a team of molecular biologists, bioinformatics scientists, instrument engineers and manufacturing specialists to develop a revolutionary single cell sequencing technology. He/she will play a key role in the development and validation of the technology as well as the commercial launch of products. He/she will also interact with external collaborators and early access customers, and provide technical support.
The ideal candidate should have extensive cellular and molecular biology experience. He/she must have direct experience on cellular assay development and RNA manipulation; strong project management skills; ability to take initiative; effective verbal and written communication skills; and be an excellent team player. RNA-Seq, NGS library preparation, and sequencing data analysis skill under both Linux and Windows environment are desired; Molecular biology reagent kit development experience is a plus.
Key Responsibilities:
Lead NGS based single cell sequencing assay and reagent kit development
Establish product quality control assays for in-process & final product test and deliver well-characterized & robust processes to manufacture
Design and execute experiments, and analyze data independently
Support current product improvement and commercialization
Interact with collaborators and customers to promote UST technology and product
Qualifications:
Ph.D. in molecular biology, cellular biology, biochemistry or related fields (M.Sc. with exceptional experience will be considered)
Minimum 3-years of cellular assay development and gene expression profiling experience
Single cell sequencing library preparation, immune repertoire sequencing or early tumor detection experience is a plus
Product development experience is preferred
Auto-ApplyScientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplyScientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
* Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
* Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
* Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
* Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
* Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
* Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
* Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
* Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
* Proven hands-on experience with multiple mammalian expression platforms is required
* Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
* Experience with therapeutic antibody developability assessment is highly desirable
* Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
* Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplyScientist, Protein Production and Characterization
Research scientist job in San Diego, CA
Scientist, Protein Production and Characterization
AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success.
Responsibilities
Responsibilities:
Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems
Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required
Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics
Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets
Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems
Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making
Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment
Qualifications
Qualifications:
Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required
Proven hands-on experience with multiple mammalian expression platforms is required
Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required
Experience with therapeutic antibody developability assessment is highly desirable
Strong analytical, troubleshooting, and communication skills with exceptional attention to detail
Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation
About AlivaMab Biologics
AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success.
The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity.
AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.
#LI-DNI
Auto-ApplyResearch Biologist
Research scientist job in San Diego, CA
Research Biologist needs 2-3 years experience
Research Biologist requires:
Degree in biology
Laboratory equipment and procedures.
MS Office
Lab techniques
Research
Biochemistry
Cell biology
Experience in running biochemical and immunological assays.
Research Biologist duties:
Ø Conduct experiments to identify and validate drug targets.
Ø Support assay design, optimization, validation, and data analyses.
Ø Design and execute molecular and cell biology experiments.
Ø Troubleshoot and analyze complex data in support of drug discovery projects.
Ø Presentation of results and conclusions both orally and written.
Scientist I
Research scientist job in San Diego, CA
Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience
Responsibilities:
The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat
Qualifications
Minimum Bachelor's degree in a biological science discipline
Additional Information
College degree or HS Diploma with +5 years biopharmaceutical industry experience
Associate Scientist - Assay Development
Research scientist job in Vista, CA
How you will contribute:
We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company.
What you will be working on:
Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing.
Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes.
Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color.
Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing.
Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research.
What you bring to Plantible:
B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering.
3 to 5+ years of industry experience in assay development in an industrial environment.
Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer.
Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes.
A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action.
Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred.
Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills.
Excellent verbal and written communication and presentation skills.
Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment.
Thrive in a fast-paced environment where the primary focus is on simplification and optimization.
Choose Plantible Foods
Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment.
At Plantible we are continually working on our offerings to foster the best team. Check it out!
Competitive health and wellness benefits
Medical, Dental and Vision Insurance
Discretionary Unlimited PTO Program
Paid Holidays
401k Program
Career Stipend
Career development and growth opportunities
Working in a rapidly growing, flexible and entrepreneurial environment
Team building and company-wide events
Financial support with your relocation, if necessary, ensuring a smooth transition
Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time.
If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!
In Vivo Research Associate II, Large Animal
Research scientist job in San Diego, CA
Job Description
In Vivo Research Associate II
FLSA Status: Non-Exempt
Pay Rate: $28 - $32 /hr
Pharmaron (San Diego) is seeking to hire an outstanding candidate to join our Medical Device department at the Research Associate II level. The Research Associate will play an important role by supporting in vivo studies to test medical devices. This position requires a broad knowledge of animal anatomy, physiology, and biochemistry to help develop and support in vivo models to screen therapeutics and devices being developed for various indications.
Responsibilities:
Experience in the administration of test substances by various basic methods (i.e., oral gavage, SQ, IV, dermal, etc.)
Manage and observe animals for general health and overall wellbeing.
Experience in the collection of biological specimens (i.e., blood from appropriate vessels from all species of laboratory animals at the site)
Able to perform study related activities in compliance with Good Laboratory Practice Regulations (GLPs), study protocols, and company policies and Standard Operating Procedures (SOPs)
Review documentation to ensure functions performed meet quality control requirements.
Handle, restrain, and provide care for all species of laboratory animals at the site.
Perform study preparation activities, including collection tube labeling and room setup.
Perform catheter placements in large animals.
Perform surgical procedure: intubation, anesthesia, pain recognition and analgesia.
Monitor animals under anesthesia and during post-operating monitoring and recovery.
Perform biopsies and skin excisions.
Perform necropsies and tissue collection.
Interface with different teams, including study director, principal investigator, QC/QA, and Account Managers/Sales.
Maintain accurate records in various internal databases.
Support internal research projects to optimize service offerings. Perform aseptic techniques.
Perform other duties as directed by management.
What We're Looking For:
We're seeking individuals who have strong communication skills with attention to detail who thrive in fast-paced environments.
Associates degree (preferred) in veterinary technology with 3 years relevant experience.
BS with at least 2 years relevant experience.
Education level requirements could be amended based on relevant years of experience.
Certification as a registered veterinarian technician (RVT) is a plus.
Background in lab animal (in vivo) research is a must.
Working knowledge of preclinical techniques and modalities will be a plus.
Position requires good communication skills and attention to detail.
Strong work ethic, self-motivation, and ability to adapt to a dynamic team environment.
Why Pharmaron?
Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.
Collaborative Culture: You'll thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.
Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
Insurance including Medical, Dental & Vision with significant employer contributions
Employer-funded Health Reimbursement Account
Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
401k plan with generous employer match
Access to an Employee Assistance Program
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
#LI-MC1
Associate Scientist I, Discovery Chemistry (Bioconjugation)
Research scientist job in San Diego, CA
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry.
Responsibilities
Maintain a well-documented laboratory notebook
Track progress against project timelines, generate regular status updates, and communicate progress and issues to management
Perform tasks across projects
Manage time effectively to meet deadlines
Adhere to safe laboratory practices
Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines
Requirements:
B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry
0-3 years of experience working in a chemistry laboratory
Experience with a wide range of analytical techniques, especially HPLC
Ability to quickly learn new procedures and techniques
Preferred:
Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting
Experience with solid-phase peptide synthesis (automated and/or manual)
Prior experience in a pharmaceutical or biotechnology environment
California pay range $60,000-$80,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.
California Applicant Privacy Policy
Auto-ApplyOncology Late Stage Clinical Scientist (Senior Manager, Non MD)
Research scientist job in San Diego, CA
You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate . Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams , governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s , analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings , seeks opportunities to further improve quality and efficiency of clinical procedures; MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 2 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 5 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 7 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval. Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance. Experience working on large data sets. Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience building partnerships across the company to achieve the needs of the program. PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology. Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned. Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities. Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes. Leverages knowledge and support from others related to overall objectives , strategy, critical issues, and policies. Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes. Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies . Work Location Assignment: This is a Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical
Research Associate I
Research scientist job in San Diego, CA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
Job Description
As a Research Associate you will support the development of novel microfluidic platforms. You will be part of a multidisciplinary team solving complex problems, working on integration issues and investigating new research areas. Candidates that are engineering with a foundation in biology are better suited for this role vs. pure biologists.
Hands-on testing, integration and optimization of microfluidic systems including fluidics, hardware, firmware, software, and chemistry/reagents Quickly fabricate and test prototyped microfluidic systems Conduct system level testing, assay testing, image analysis Translate benchtop assays to prototype microfluidic systems Use standard lab instrumentation: fluorescence plate readers, fluorescence microscopes, thermocyclers, bioanalyzers, DNA sequencers, syringe pumps Develop and implement experimental test plans Record and analyze complex data sets Develop creative solutions to troubleshoot issues Willingness to be hands-on Share and record experimental results for an audience with broad technical backgrounds at technical meetings
Qualifications
Skills:
Microfluidics Experience with prototyping microfluidic systems: 3D printers, CO2 laser, laser ablation, profilometry Demonstrated ability to understand and successfully work across multiple disciplines including engineering, biology, and software is highly desired
1-2 years of experience in a clean room
1-2 years of experience in a lab environment with wet biology or chemistry experience
1-2 years of experience in product development is highly desired Experience in a BSL-2 lab is a plus Experience with sequencing, library prep and PCR is highly desired Organized and detail oriented Clear communicator and a team player Multidisciplinary approach to problem solving A desire to be part of face paced dynamic environment
Education and Experience
Undergraduate degree in Mechanical Engineering, Bioengineering, Chemical Engineering, Analytical Chemistry, or Physics
Additional Information
Vishnu Kumar
Technical Recruiter
Artech Information Systems LLC
360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960
Office: *************** | Fax: ************
Research Biologist
Research scientist job in San Diego, CA
Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry
Research Biologist requires:
Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry
Experience in running biochemical and immunological assays.
Highly motivated and agile biochemist
Research Biologist duties:
Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies
Perform basic tasks to support tissue culture and maintenance of immune competent cell lines
Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.)
Work with a cross-disciplinary team for data analysis
Independently execute experiments, analyze, interpret and present experimental data
In Vivo Research Associate I, II, or III
Research scientist job in San Diego, CA
In Vivo Research Associate I, II, or III Department: Ophthalmology FLSA status: Non-Exempt Pharmaron San Diego is seeking a motivated In Vivo Research Associate (I, II, or III) to join our Ophthalmology team. In this role, you will support preclinical in vivo ophthalmic studies and contribute to developing novel therapies for eye diseases. The ideal candidate will have hands-on experience working with laboratory animals, administering test articles, collecting specimens, and performing ophthalmic procedures in a fast-paced research environment.
Depending on your level of experience I, II or III Additional tasks:
* Administer test substances using routes such as oral gavage, SQ, IV, ID, and topical ocular dosing across multiple species.
* Observe, monitor, and assess animal health and welfare.
* Perform biological specimen collection, including blood draws and tissue sampling from various laboratory species.
* Execute study tasks in compliance with GLP regulations, study protocols, SOPs, and company policies.
* Perform Intraocular Pressure (IOP) measurements using Pneumatonometer or Tonovet.
* Restrain and handle animals for ophthalmic imaging and diagnostic assessments.
* Assist with necropsies and ophthalmic tissue collections.
* Support surgical procedures and provide assistance to the operating surgeon.
* Perform and monitor anesthesia and analgesia, including post-operative recovery.
* Conduct study setup activities including room preparation, supply staging, and tube labeling.
* Perform aseptic techniques and follow biosafety and animal care guidelines.
* Place catheters in small and large animals as required by study design.
* Maintain accurate, timely data entry in internal systems including eQCM, Provantis, and Vivarium+.
* Perform other duties as directed by Management.
What We're Looking For:
* In Vivo Research Associate I: Associate degree in veterinary technology with 1-2 years of experience, or BS with 1 year of experience.
* In Vivo Research Associate II: Associate degree in veterinary technology with 3 years relevant experience, or BS with 2 years of experience.
* In Vivo Research Associate III: Associate degree in veterinary technology with 4 years relevant experience, or BS with 3 years of experience.
* A combination of education and relevant hands-on experience will be considered.
Preferred Qualifications:
* Registered Veterinary Technician (RVT) certification is highly desired, particularly for candidates with anesthesia, surgical support, or ophthalmic procedure experience.
* Prior experience in ophthalmology, in vivo models, or preclinical research.
* Working knowledge of animal handling, dosing techniques, clinical observations, and specimen collection.
* Strong attention to detail, documentation accuracy, and ability to follow strict regulatory procedures.
* Excellent communication skills and the ability to thrive in a collaborative, fast-paced environment.
* Strong work ethic, self-motivation, and ability to adapt to a dynamic team environment.
Why Pharmaron?
Pharmaron stands as a leading force in the life sciences industry, offering premier R&D services to partners across the globe. With a workforce of over 20,000 professionals and operations spanning China, the U.S., and the U.K., Pharmaron is committed to delivering innovative R&D solutions that drive advancements in healthcare.
Collaborative Culture: You'll thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators.
Comprehensive benefit package: As part of our commitment to your well-being, we offer a comprehensive benefits package, including medical, dental, and vision insurance with significant employer contributions. Planning for your future is made easier with our 401k plan and employer match. Plus, you'll have access to an Employee Assistance Program to support you in work and life.
The hourly rate for In Vivo Research Associate I: $24 - $28
The hourly rate for In Vivo Research Associate II: $28 - $32
The hourly rate for In Vivo Research Associate III: $32 - $35
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
Got Questions?
If you have any questions about the role or our company, don't hesitate to reach out. We're here to help!
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
#LI-MC1