Research scientist jobs in Temecula, CA - 504 jobs

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at*************** Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok. Job Description Discovery Biotherapeutics and Genetic Medicine (BGM) at AbbVie is seeking a highly motivated Principal Scientist to join the Biotherapeutics group at the AbbVie Bay Area (ABA) site based in South San Francisco, CA. This role seeks a skilled and experienced individual to contribute to and lead therapeutic programs, focusing on biophysical screening to advance biotherapeutics from early exploration through lead identification and optimization. Close partnerships with Oncology will be required to drive transformative ideas to the clinic. The ideal candidate must possess expertise in high-throughput biologics screening and characterization methods (e.g. ELISA, FACS, BLI, SPR, etc.) and have a solid foundation in protein sciences and antibody discovery with a proven ability to work effectively on cross-functional teams. Responsibilities Lead from the lab to advance large molecule biologics projects from exploratory to optimization stages and drive Go / No Go decisions. Effectively partner with functional and therapeutic areas to achieve project objectives. Identify and integrate cutting-edge technologies and methodologies into screening and assay development, anticipating future trends in drug discovery. Multitask and work within timelines while maintaining a high level of productivity. Supervise 1-2 scientists, evaluate team performance, and is accountable for the effective performance of team. Qualifications BS, MS, or PhD with typically 14+ (BS), 12+ (MS), or 6+ (PhD) years of relevant experience. Experience with biologics, monoclonal antibodies and/or protein therapeutics. Experience advancing Discovery programs from exploratory to candidate nomination. Independently develop and execute biosensor and cell-based platforms to evaluate panels of antibody biotherapeutics. Implement high-throughput epitope binning for large panels of monoclonal antibodies and develop deep knowledge of antibody sequence/function relationships. Evaluate and integrate biomolecular interaction technologies (e.g., SPR) to guide therapeutic candidate selection recommendations. Expert in biophysical characterization instrumentation and methodologies such as SEC, MS, HDX-MS, X-ray crystallography, DSF, DLS, etc. Challenge the status quo and onboard cutting-edge technologies to drive discovery and innovation. Excellent attention to detail, record keeping, and organization. Excellent communication, presentation, and collaboration skills. Preferred Qualifications Antibody sequence and structure knowledge. Structure-based molecular modeling and applications with AI/ML and integrating complex datasets to drive data-based decisions. CRO and external partner management. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. This job is eligible to participate in our long-term incentive programs. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 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A biopharmaceutical company in San Diego seeks a Principal Scientist to lead an in vitro pharmacology team. Candidates should have a Ph.D. and over 8 years in drug discovery, particularly with GPCRs. Responsibilities include designing assays, managing a team, and collaborating on research projects. The competitive salary ranges from $158,000 to $197,000, with comprehensive benefits including health insurance and PTO. #J-18808-Ljbffr

Come join our collaborative and creative group of AI scientists and machine learning engineers and build models that directly affect hundreds of thousands of our customers. In this role you will be building and deploying machine learning models using both analytical algorithms and deep learning approaches. We are waiting for you to join us and do the best work of your life. Responsibilities Practices excellent leadership and communication skills to influence and lead teams and to evangelize AI science across the organization Leads team's work in one or more of: ML, NLP, Statistics, or Optimization, performs hand-on work in these domains. Weighs ROI considerations of general and tailored capabilities for projects in the team Creates new capabilities that solve critical business problems Pushes the boundaries of ML by developing foundational methods and novel applications from state-of-the-art ML technologies and industry trends Influences business leaders to shape mission critical projects Creates multi-year vision that connects product strategy with technology strategy Drives architecture decisions, influences and contributes to ML platform architecture and strategy Leads team and partners to the successful delivery and integration of ML solutions Conducts design reviews, holds teams to technical and operational rigor Acts as an advisor in overseeing and mentoring the work of colleagues towards the building of a vibrant practice community Pay offered is based on factors such as job-related knowledge, skills, experience, and work location. To drive ongoing pay equity for employees, Intuit conducts regular comparisons across categories of ethnicity and gender. Qualifications PhD/MS in Engineering Mathematics, Statistics, Theoretical/Computational Physics, or related field Solid knowledge of statistical techniques 3+ years as either a lead in a AI science role or in a management position in AI science Strong communication skills and proven experience as an influencer at the executive level Hands-on programming experience and expert knowledge in one or more of: ML, NLP, Statistics, or Optimization 6+ years' experience manipulating large datasets and using databases (e.g. R, SQL, S-Plus, etc.) 6+ years' experience with a general-purpose programming language (e.g. Python, Scala, etc.) Expert knowledge and hands-on experience with ML pipelines, processes, and design patterns Proven track record of influencing business leaders to shape mission critical projects Proven track record of leading team to successful delivery of ML solutions Strong interpersonal and communication skills in order to effectively contribute to technical teams and make presentations to a variety of technical and business personnel Intuit provides a competitive compensation package with a strong pay for performance rewards approach. This position will be eligible for a cash bonus, equity rewards and benefits, in accordance with our applicable plans and programs (see more about our compensation and benefits at Intuit : Careers | Benefits). Pay offered is based on factors such as job-related knowledge, skills, experience, and work location. To drive ongoing fair pay for employees, Intuit conducts regular comparisons across categories of ethnicity and gender. The expected base pay range for this position is: Southern California, CA: $237,000 - $320,500 #J-18808-Ljbffr

A global healthcare company based in San Diego is looking for an experienced scientist to lead biologics discovery and development. This role involves working cross-functionally with Immunology teams and external partners to innovate therapeutics focusing on antibodies and multicentric projects. Candidates should possess a strong background in protein therapeutics with respective educational qualifications and experience. A commitment to diversity and inclusion within the workplace is essential. #J-18808-Ljbffr

Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US. What You Will Do (Key Responsibilities) Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents. Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts. Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches. Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making. Adapt to a fast-paced environment where innovation and quick iteration are encouraged. What you'll bring PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD. Deep understanding of structure-based drug design and protein-ligand interactions. Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite. Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs. Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists. We are open to remote team members too. What we offer Competitive Pay Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) Stock Option Eligibility 401(k) Plan Open PTO Policy Paid Company Holidays Subsidized lunch and snacks at our offices Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer. #J-18808-Ljbffr

Join a pioneering startup founded by a renowned Professor, in shaping the future of environmental sustainability. As a Senior R&D Scientist, you will lead the charge in developing cutting-edge CO2 capture technologies, driving innovations that can significantly impact the global fight against climate change. Why You Should Apply Be a key player in pioneering CO2 capture technology. Competitive salary and benefits package. Work with a team of distinguished scientists and engineers. Contribute to groundbreaking research with global environmental impact. Join a startup environment that values diversity, collaboration, and innovation. What You'll Be Doing: Collaborate with the head of Product Engineering to scale up MOF/COF-based CO2 capture systems. Model the kinetics, thermal transfer, and CO2 adsorption/desorption mechanisms. Develop and optimize models for CO2 capture, including energy efficiency and air flow. Design and scale technologies from prototype to commercial stage. Optimize system parameters to enhance performance and efficiency. Collaborate with R&D scientists on technical specifications. Evaluate and manage sourcing of materials and components. Establish QC/QA processes and maintain detailed electronic notebooks. Contribute to the company's intellectual property and participate in technical meetings. About You: PhD in mechanical engineering, chemical engineering, or a related field with a strong research background. Experience in CO2 capture industry and pressure swing adsorption systems. Proficient in thermodynamics, fluid mechanics, and heat transfer. Over 5 years of industrial R&D experience, with 3-5 years in the CO2 field. Skilled in designing system-level prototypes and using simulation tools. Familiar with health and safety procedures in production. Excellent teamwork, problem-solving, and communication skills. How To Apply We'd love to see your resume, but we don't need it to have a conversation. Send us an email to *********************** and tell us why you're interested. Or, feel free to email your resume. Please include Job#19656

A leading global healthcare firm in San Diego is seeking a highly motivated scientist to contribute to biotherapeutics development. The successful candidate will discover and engineer antibodies, oversee experiments, and utilize various molecular biology techniques. Applicants should have at least 6 years of relevant experience and a strong background in flow cytometry. This position offers competitive compensation ranging from $110,250 to $187,000 along with comprehensive benefits. #J-18808-Ljbffr

Schedule: Monday-Friday, 8:00 AM - 5:00 PM Duration: 6-Month Contract (coverage for leave) Pay: 40-44 USD per hour We are seeking a skilled Scientist with a strong background in biochemical, biophysical, and analytical sciences to join a Method Development & Transfer team. In this role, you will design, develop, and transfer analytical assays used to characterize critical components supporting reagent development and manufacturing. This position is highly collaborative and plays a key role in ensuring analytical methods are robust, validated, and ready for use in regulated manufacturing environments. Key Responsibilities Develop and optimize analytical methods for oligonucleotides, enzymes, and liquid reagent consumables Apply analytical techniques such as HPLC, UV-Vis, and fluorescence spectroscopy (LC-MS strongly preferred) Support method development, qualification, validation, and transfer into manufacturing and QC environments Partner cross-functionally with Development, Quality Control, and Manufacturing teams Design and support QC assays to enable new product readiness Prepare technical documentation to support regulated manufacturing processes Select, qualify, maintain, and troubleshoot analytical instruments and software Define process requirements including instrumentation, documentation, and training needs Plan and execute laboratory experiments with a high level of scientific rigor Analyze data, troubleshoot issues, and provide technical recommendations May provide guidance or oversight to junior staff or research associates Required Qualifications BS or MS in Chemistry, Biochemistry, Biology, or related scientific discipline 3-5 years of industry experience in analytical or biochemical method development Hands-on experience with HPLC (required) Experience with UV-Vis and fluorescence spectroscopy Strong background in analytical characterization of enzymes and/or oligonucleotides Ability to manage multiple priorities in a fast-paced environment Strong written and verbal communication skills Preferred Qualifications Experience with LC-MS or other advanced analytical techniques Exposure to method validation and transfer into Manufacturing or QC Experience working in regulated or GMP environments Familiarity with next-generation sequencing platforms Experience working with laboratory databases or LIMS systems ...

Yoh Life Sciences is hiring a long term contractor for a Senior Research Associate, Neuroscience / Cell-Based Screening in San Diego, CA. We are seeking a highly motivated Senior Research Associate with strong expertise in cell-based screening and assay development to support drug discovery programs focused on neuronal targets. The ideal candidate will bring hands-on experience with high-throughput and high-content screening, preferably in an industry setting, and will play a key role in assay development, screening execution, and hit-to-lead activities. Title: Sr. Research Associate Location: San Diego proper Pay: $34-40/hr DOE Schedule: M-F 9-5pm Duration: contract with ability to convert to perm Key Responsibilities Design, develop, and execute primary high-throughput screening (HTS) assays Optimize and run counter-screens and SAR assays to triage and characterize hits from primary screening campaigns Develop and optimize in vitro assays using human iPSC-derived neurons to support mechanism-of-action (MOA) studies Analyze, interpret, and clearly present experimental data to project teams Collaborate closely with medicinal chemistry, biology, and pharmacology teams to advance programs Maintain detailed experimental documentation and ensure high scientific rigor and reproducibility Qualifications Bachelor's or Master's degree in Biology, Neuroscience, Pharmacology, or a related discipline Cell-based screening experience, including high-throughput and/or high-content screening, ideally in an industry setting Experience with neuronal cell culture, with preference for human stem cell-derived NPCs and neurons Proficient in immunofluorescence Hands-on experience with assay development and optimization Familiarity with automated liquid handling and screening platforms Strong data analysis, troubleshooting, and experimental design skills Ability to work independently while contributing effectively within cross-functional teams Preferred Skills Experience with flow cytometry Exposure to drug discovery workflows, including HTS, SAR, and lead optimization Comfort working in a fast-paced, collaborative research environment #IND-SPG Estimated Min Rate: $34.00 Estimated Max Rate: $40.00 What's In It for You? We welcome you to be a part of the largest and legendary global staffing companies to meet your career aspirations. Yoh's network of client companies has been employing professionals like you for over 65 years in the U.S., UK and Canada. Join Yoh's extensive talent community that will provide you with access to Yoh's vast network of opportunities and gain access to this exclusive opportunity available to you. Benefit eligibility is in accordance with applicable laws and client requirements. Benefits include: Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week) Health Savings Account (HSA) (for employees working 20+ hours per week) Life & Disability Insurance (for employees working 20+ hours per week) MetLife Voluntary Benefits Employee Assistance Program (EAP) 401K Retirement Savings Plan Direct Deposit & weekly epayroll Referral Bonus Programs Certification and training opportunities Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply. Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. Visit ************************************************ to contact us if you are an individual with a disability and require accommodation in the application process. For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. By applying and submitting your resume, you authorize Yoh to review and reformat your resume to meet Yoh's hiring clients' preferences. To learn more about Yoh's privacy practices, please see our Candidate Privacy Notice: **********************************

OHR uses primordial chemistry and synthetic biology to fashion strategic chemicals. Our technology enables the creation of carbon chains of deterministic length without cells, co-factors, or typical oil contaminants. With a core value of sustainability, OHR is focused on building resilient supply chains through innovative solutions. Role Description OHR Synbiosis seeks Sr. Research Associates in Chemistry R&D to drive technical developments across R&D groups and between the broader OHR organization. The candidates will assist in, execute, and design experiments in synthetic chemistry routes of OHR's Creationary Chemistry TM platform, including organic chemistry synthetic pathway exploration and discovery, reaction process optimization, catalyst development, analytical methodologies, product application, and external technical partnership management. Responsibilities Exemplify excellence in lab safety and chemical hygiene practices. Perform research and development on OHR's Creationary Chemistry TM platform. Be a workhorse in the drive to deliver critical chemicals to public and private customers in need. Assist in discovery of organic and synthetic chemistry reactions to create novel synthetic routes leveraging OHR's proprietary enzymatic intermediates. Explore chemical reaction development across product pathways, including solvent selection, catalyst elucidation/optimization, reaction conditions, etc. Contribute to design, optimization, and scaling of catalytic processes, including acid/base catalysis, heterogenous supported-metal and inorganic catalysis, hydrogenation, and hydrodeoxygenation. Generate data to aid analytical methodology development, in-house and with partners, to build quantitative standing of chemical reactions. Build testing and characterization protocols for OHR's aviation and aerospace fuel product portfolio and additional proprietary emerging product portfolios. Design, test, build, and validate novel heterogeneous inorganic catalysts. Contribute to research and IP strategies to solidify the Creationary Chemistry TM platform. Draft, optimize, publish, and train colleagues on technical procedures and specialized reactions. Provide detailed data and protocols for technology transfer to OHR's Manufacturing team and external partners. With Project Managers and Executives, implement project management systems to track Chemistry R&D developments and KPIs. Required Qualifications Bachelor's of Science in Chemistry, or equivalent area, from an accredited university. Exemplary past demonstration of lab and workplace safety. Direct experience contributing to technical chemistry research and development teams through: discovery of synthetic chemistry pathways, contributing to process chemistry and reaction optimization, exploring and selecting or synthesizing and evaluating heterogeneous metal catalysts for hydrogenation and reduction chemistry, discovering or optimizing acid and base catalyzed reactions, or developing of analytical methods of compound identification and quantification, including utilization of GC-FID, HPLC, LC/MS, GC/MS, NMR, and ICP. Direct hands-on experience converting established batch reactions to flow/continuous reactions.

A biotechnology company in San Diego is seeking a Senior Principal Scientist specializing in DMPK Translational PKPD Modeling. The role involves developing mechanistic PK/PD models, leading drug discovery project teams, and collaborating with diverse research disciplines. Candidates must hold a PhD in Biochemistry or related field and possess substantial industry experience in pharmacokinetics. The position offers a competitive salary range of $156,900 to $214,000 with additional benefits including bonuses, retirement plans, and comprehensive health coverage. #J-18808-Ljbffr

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Research Biologist needs 2-3 years experience Research Biologist requires: Degree in biology Laboratory equipment and procedures. MS Office Lab techniques Research Biochemistry Cell biology Experience in running biochemical and immunological assays. Research Biologist duties: Ø Conduct experiments to identify and validate drug targets. Ø Support assay design, optimization, validation, and data analyses. Ø Design and execute molecular and cell biology experiments. Ø Troubleshoot and analyze complex data in support of drug discovery projects. Ø Presentation of results and conclusions both orally and written.

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Job Description Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy

Kindbody is the leading fertility clinic network and global family-building benefits provider for employers offering the full-spectrum of reproductive care from preconception to postpartum through menopause. Kindbody is the trusted fertility benefits provider for 132 leading employers, covering almost 2.9 million lives. As the fertility benefits provider, technology platform, and direct provider of care, Kindbody delivers a seamless, integrated experience with superior health outcomes at lower cost, making fertility care more affordable and accessible for all. Kindbody has raised $315 million in debt and equity funding from leading investors including Perceptive Advisors, JP Morgan Chase's Morgan Health, GV (formerly Google Ventures), RRE Ventures, Claritas Health Ventures, Rock Springs Capital, Distributed Ventures, Whatif Ventures and TQ Ventures. Visit ***************** and follow us on Instagram, Twitter, and Linkedin. Kindbody's clinically-managed program covers the full-spectrum of reproductive health, including both female and male fertility, which encompasses fertility assessments and education, fertility preservation, genetic testing, in vitro fertilization (IVF), donor and surrogacy services, and adoption, as well as a full continuum of reproductive care including physical, mental, and emotional support. About the Role As an experienced Senior Embryologist reporting to our Lab Managers in various locations, you will be working in a fast-paced, rapidly growing environment where you will be relied on for your expertise, professionalism, and collaboration. Proposed Schedule: 18 days per month in lab (travel day included) and 1 week remote admin work, subject to change based on the needs of the business. Responsibilities Perform assisted reproductive technology methods including, but not limited to, semen preparation, oocyte identification conventional IVF, ICSI, embryo culture and grading, laser assisted hatching, trophectoderm biopsy, sperm, oocyte and embryo cryopreservation (vitrification). Maintain accurate laboratory records Perform quality control procedures and monitor KPIs Participate in the laboratory's quality management program Coordinate with reproductive endocrinologists and OB/GYNs to assist their patients with reproductive health issues and clinical research. Educate patients on infertility evaluations, medications, treatment protocols and procedures Provide patient/couple counseling, procedure teaching, communicates physician orders and instructions Ensure all patient information is documented appropriately in our EMR according to our procedures Works independently to assure the program goals are achieved Support and promote excellence in customer service Provide feedback to HQ on process improvement and job specifications to help gain efficiencies in the day to day Who You Are Willingness to be flexible and travel nationwide to any of our 20 clinics 6+ years experience in clinical embryology {3-4 of which are micromanipulation} Able to work independently with minimal supervision Proficiency in all IVF laboratory methods including micromanipulation techniques and vitrification Detail oriented, meticulous record-keeping Strong communication skills & a team player Familiarity with all state and local regulations including tissue bank licensing Experienced in EMR and G-Suite

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. Our teams combine leading drug discovery capabilities and world‑class R&D to turn breakthrough science into life‑changing medicines. Our Research and Development Division in San Diego is a cross‑functional team (Discovery Biologics, Immunology, and Data Science) focused on discovering and developing novel, innovative therapeutics in the field of Inflammation and Immunology. The Discovery Biologics Department is seeking an exceptional and experienced scientist to drive biologics discovery and development. The successful candidate will lead projects from discovery to the start of IND‑enabling studies, with a focus on antibodies, bispecific molecules, and evaluation of novel biologic platforms and mechanisms of action. Key Responsibilities Lead the design, engineering, and characterization of innovative biologics, including antibodies and bispecific molecules. Direct the Protein Sciences team in the production and purification of antibodies in mammalian cell lines (transient HEK, CHO) and antigen/protein reagents required for the drug discovery portfolio. Drive innovation by contributing to exploratory programs and technology development. Provide strategic project leadership and partner cross‑functionally with teams in discovery, pharmacokinetics, pharmacodynamics, toxicology, CMC, translational sciences, and translational medicine. Lead and mentor a team of scientists. Foster a high‑performance culture of collaboration, engagement, self‑accountability, and inclusion. Partner across multidisciplinary interfaces to achieve organizational objectives. Stay abreast of external advancements in the relevant scientific fields. Promote the external reputation of the Discovery Biologics Department through publications and conference presentations. Education Bachelor's (≈14 years experience), Master's (≈10 years experience), or Ph.D. (≈7 years experience) in Immunology, Molecular Biology, Biochemistry, Cellular Biology, or a related field, with relevant experience. Required Experience and Skillsh3> Deep scientific knowledge across workflows and domains integral to the discovery and development of protein therapeutics. Expertise in therapeutic protein design, engineering, and characterization. Experience advancing a biotherapeutic program from discovery into development and applying scientific or platform innovations. Demonstrated passion for talent development and a proven track record. Champion for a diverse and inclusive culture. Excellent verbal and written communication skills. Strong external reputation through publications, presentations, and scientific community engagement. Preferred Experience and Skills Experience with protein therapeutics beyond traditional mAbs, including alternative non‑Ig scaffolds, bi‑ or multispecifics, and fusion proteins. Fluency in techniques for analyzing protein-protein interactions. Knowledge of computational approaches for protein engineering. Experience in outsourcing and managing external collaborations. Salary and Benefits Salary Range: $156,900.00 - $247,000.00. The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable. We offer a comprehensive benefits package, including medical, dental, vision, 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at ******************************************************* Application You can apply for this role through **************************** or via the Workday Jobs Hub if you are a current employee. The application deadline for this position is indicated on the posting. Current employees and contingent workers are encouraged to apply. Legal and Equal Opportunity Information As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. We comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under U.S. Equal Opportunity Employment laws, visit EEOC websites. We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills, and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. #J-18808-Ljbffr

A global healthcare leader in San Diego seeks a highly motivated scientist to contribute to the discovery and development of biotherapeutics. The role involves discovering and optimizing antibodies, utilizing flow cytometry, and requires strong skills in molecular biology and biochemistry. Ideal candidates should have significant industry experience and be detail-oriented, with excellent communication skills. Competitive compensation and benefits include a flexible benefits package and bonus potential. #J-18808-Ljbffr