REVOLUTION Medicines jobs

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a Director, US Strategic Pricing to lead the net and list price analysis and recommendations for in-line and pipeline strategies and tactics with primary internal stakeholders to maximize brand and portfolio corporate value. The Director, US Strategic Pricing will serve as a subject matter expert in US Market Access and Oncology price strategy with deep knowledge of mandated and commercial payer environments, US pricing policy and government and global pricing interdependences, and gross to net inputs and analytics. The Director will report to the Senior Director, US Strategic Pricing and will serve in a critical function to shape pricing strategy and net price life cycle management as the company transitions into a commercial organization. This role can be based from RevMed's Redwood City, CA location or can be remotely based with up to 15% travel. Key Responsibilities Lead and align recommendations and input for executive decision-making or informational executive summaries based on quantitative and qualitative analysis across potential outcomes of price-related business opportunities or risks. In partnership with the Senior Director, US Strategic Pricing and internal stakeholders, develop, define and model strategies to support US Market Access for key accounts including: Oncology GPOs, Physician Networks, IDNs, Payers and other national or emerging customers of importance in support of the US Market Access customer engagement teams. Effectively partner with internal stakeholders to develop relationships to drive strategy access, adoptions and data to support the business and supply analytics to optimize revenue. Collaborate on relevant commercial department initiatives to create effective analytics to monitor and analyze payer/provider access, reimbursement access, channel access, customer targeting, and data contracting to ensure alignment with key account management objectives. Proactively research and interpret relevant policy/industry/competitive information and determine implications to the industry, organization, and opportunities to develop innovative strategies, tactics and solutions in support of US market Access organization or mitigate risk to the organization. Ensure compliance with all applicable laws, regulations, and company policies related to pricing and contracting. Required Skills, Experience and Education: Bachelor's degree. Minimum of 8 years of pharmaceutical payer experience. 2+ years of Oncology product experience. 10+ years Gross to Net, pricing, and payer/provider contracting experience to support mandated and discretionary price initiatives. Expert modeling skills to support net price and price strategy decisions. Strong understanding of ASP, AMP, BP, FSS, URA/340B price calculations and relationship within IRA policy guidelines and calculations. Experience in understanding and analyzing the impact of oncology clinical pathway and payer formulary access. Strong knowledge of trends, issues and policies influencing drug pricing and oncology market. Understanding of contract strategy, market analytics, and public policy to support external environment impacts to products and/or portfolio. Ability to communicate effectively, both orally and in writing. Ability to effectively deliver reports, plans, and presentations to a variety of audience types across all levels of the organization with impact. Embrace cross-functional collaboration with internal and external customers; possesses the interpersonal skills to develop and maintain cooperative working and business relationships. Ability to effectively resolve conflicts and multi-department alignment to delivery commercial goals and objectives. Embodies RevMed's values: Tireless Commitment to Patients, Transformative Science, Exceptional Together, Total Integrity, Inclusiveness and Fairness. Preferred Skills: Advanced degree (MBA, CPA) preferred. Experience supporting a first product launch at a clinical-to-commercial biotech company. #LI-SS2 #LI-Remote The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. Base Pay Salary Range$193,800-$242,250 USD

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. Intern, Drug Safety Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. The Opportunity Denali is seeking a motivated candidate for an internship position in the Drug Safety team to support safety surveillance activities and drug safety operations. Responsibilities * Support ongoing drug safety and pharmacovigilance activities for investigational and marketed products under the supervision of experienced Safety Scientists and Physicians * Participate in signal detection activities, including trend analysis and data visualization * Contribute to Safety Management Team (SMT) meeting preparation, minutes, and follow-up actions * Support preparation of safety sections of safety and regulatory documents (e.g. Investigator's Brochure, Study Protocols, Aggregate Reports) * Support Drug Safety Operations activities * Perform other duties or activities as assigned to support departmental objectives and cross-functional initiatives Requirements * Candidates pursuing a Doctor of Pharmacy degree (PharmD) (preferably entering P3 or P4 year) * Self- and results-driven, organized, resourceful, adaptable and collaborative * Bold and creative thinker with a curious nature, eager to learn about the complexities of the business of healthcare and biotech * Evident communication and analytical skills * High degree of proficiency with the MS Office Suite or Google equivalent Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state or local protected class. Job Facts * Start Date: Summer 2026 * Length of Assignment: 8 - 12 weeks * Location: South San Francisco, CA * Job Type: Paid Internship The expected wage for this position based on the South San Francisco California office location is $33.65 per hour. Paid holiday time off is based on Denali's designated holidays. Interns who live more than 50 miles away from the office are eligible for an additional housing stipend. This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. This role is responsible for developing and managing scientific data solutions leveraging commercial and custom software tools to enable the capture, management, and integration of scientific data. The role involves close collaboration with laboratory scientists, software engineers, and external partners to facilitate data capture & maximize its usefulness in the R&D process. Key Accountabilities/Core Job Responsibilities: * Develop and maintain reliable software tools for R&D functions that accelerate & improve research processes and nudge scientists to adhere to best practices. * Configure and maintain Denali's lab information management solutions, the Dotmatics and Benchling suites. * Develop and customize informatics solutions for Denali's functions, including protein and oligonucleotide therapeutics, by capturing, retrieving molecular properties along with associated experimental data. * Collaborate with a wide range of partners, including scientists, software developers, IT, and other stakeholders to deliver right-sized solutions. Maintain and improve existing tools, and contribute to long-term standardization efforts. * Provide training, documentation, troubleshooting, and support to ensure adoption and proper use of all tools and systems managed by the team * Be a champion for scientific data quality. Qualifications/Skills: * Bachelor's with 3+ years relevant experience. * Experience in a Pharmaceutical/Industrial chemistry/Biotech environment and in working with LIMS, ELN, laboratory informatics projects, and/or scientific software development. * Familiarity with common lab workflows and data management needs, and the ability to collaborate with scientists to understand and support their processes. Hands-on lab experience is a plus, but not required. * Track record of successfully delivering laboratory informatics solutions to address scientific data challenges and applying modern software engineering practices to deliver applications and/or scientific data analyses. * Experience developing and maintaining software applications or tools that are reliable, well-documented, and designed for ongoing use by others (this may come from professional software roles, research informatics, or building substantial tools in a lab setting) * Proficiency in web application development, especially using Python (Django) and SQL, as well as familiarity with software engineering practices such as version control, code review, and testing are essential. * Familiarity with cloud services, particularly AWS (e.g. EC2, ECS, and S3) and containerized environments (Docker) are highly desirable. Salary Range: $105,000.00 to $141,000.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at ****************************************** This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This role represents a unique opportunity to serve as a strategic and scientific liaison between the RVMD Research organization and our various internal and external partners and collaborators. We are seeking a highly motivated, detail-oriented, critical thinker, grounded in oncology drug discovery, with strong interpersonal, organizational and communication skills. This high-impact position will: Lead efforts to develop and define a robust strategy for review, prioritization and implementation of Research activities to support the business needs of various internal partners including R&D Leadership, Medical Affairs, Commercial and Investor Relations groups. For example, serve as a single point of contact accountable for the sourcing, collation and review of scientific materials to support training and public disclosures at scientific conferences and meetings. Leverage strong cross-functional skills to coordinate and facilitate collaborations with key stakeholders across the organization, including R&D, Medical Affairs, Commercial, Project Management, and Legal to enable aforementioned activities. Partner with Research Leadership to develop and implement an efficient and sustainable approach to RVMD's collaborations with external academic partners. Including, but not limited to, prioritization of preclinical research proposals and RVMD review and approval of scientific materials intended for public disclosure at scientific conferences and meetings. Streamline communication and decision-making processes to optimize management of both internal and external relationships for members of Biology leadership team within the context of the above activities. Identify current and future needs and evolve capabilities of scientific liaison function to adapt to rapidly increasing scale and complexity of our RAS(ON) portfolio and the broader organization. Pro-actively work with key stakeholders across the organization to maintain a detailed understanding of the portfolio and its drivers. Required Skills, Experience, and Education: PhD scientist with 12+ years of related experience including strong operational talents, solid judgement, strong communication skills, and the ability to balance multiple complex projects. Practicing scientists who want to transition to enabling scientific operations, strategy and management will be considered. 10+ years' experience in the biotech/pharmaceutical industry. Experience with Oncology drug discovery, including familiarity with key activities that follow progression of drug candidates from Research to Clinical Development and Commercialization. Able to pivot flexibly from strategy to operations and explain interconnections to collaborators with a wide variety of backgrounds and disciplines, including senior management and external stakeholders. Clear and concise communication style, in particular for scientific subject matter, with an ability to synthesize facts and insights into business-relevant, actionable recommendations. Ability to apply rigorous logic, creativity and ingenuity to develop solutions to complex problems. Strong interpersonal skills, including the ability to make decisions and influence others, and build and maintain positive work relationships with all levels in a dynamic and fast-paced organization. Keen attention to detail. Preferred Skills: Experience in academic collaborator management, portfolio management, portfolio planning or similar function(s) is preferred. #LI-Hybrid #LI-LN1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$204,000-$255,000 USD

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a highly motivated and scientifically driven field based and customer facing Director Medical Liaison / Medical Advisor to jump start Medical Affairs activities in Germany. This role will report in the beginning to the SVP Head of Europe until a VP Head of Medical Affairs Europe has joined, and later on to the Senior Medical Director Germany. This position will be instrumental in driving the scientific excellence, clinical insight, and medical strategy supporting our oncology pipeline and marketed products. The field based Director Medical Liaison / Medical Advisor will serve as the medical expert within the upcoming German affiliate, ensuring scientific integrity and alignment with global and European medical affairs and clinical objectives. The position will require close collaboration with cross-functional partners including clinical development, clinical operations, regulatory, commercial, HEOR, market access, and other field medical teams across Europe. Key Responsibilities Develop and implement an early pre-launch German Medical Affairs strategy and tactical plan for assigned products and therapeutic areas. Establish and maintain trusted scientific relationships with key opinion leaders (KOLs), investigators, and healthcare professionals across Germany. Provide medical oversight and scientific input to cross-functional teams, ensuring alignment with regulatory and compliance standards. Collaborate with other Medical Science Liaisons, Medical Affairs, and clinical research departments to support scientific exchange, education, and data dissemination activities. Contribute to medical input in promotional and non-promotional materials, internal training, and advisory boards. Plan and execute national medical meetings, symposia, and congress participation to enhance scientific visibility. Support investigator-initiated trials and local clinical research activities in collaboration with global and regional teams. Monitor the competitive and scientific landscape to inform internal strategy and provide actionable medical insights. Partner with HEOR and market access to develop real-world evidence and outcomes research projects. Ensure compliance with German and EU regulatory frameworks governing interactions with healthcare professionals. Collaborate closely with Clinical Operations and CROs, including site selection, Site Initiation Visits, and investigator engagement Required Skills, Experience and Education: Advanced scientific or medical degree (MD, PharmD, or PhD) required; oncology experience strongly preferred. Minimum 8-10 years of experience in Medical Affairs or related functions in the pharmaceutical or biotech industry. Strong understanding of oncology clinical development, evidence generation, and treatment landscape. Proven ability to interpret and communicate complex scientific and clinical data. Experience engaging with healthcare professionals, academic researchers, and medical societies. Excellent interpersonal, organizational, and presentation skills. Fluency in German and English (written and spoken). Ability to work effectively in a matrixed, cross-functional, and multicultural environment. Willingness to travel nationally and internationally (up to 25%) Preferred Skills: Prior experience in oncology product launches Strong network within the German oncology community. Experience in investigator-initiated or real-world evidence studies. Knowledge of German healthcare systems, reimbursement structures, and compliance requirements. Track record in publication planning, congress presentations, and scientific communications. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Remote #LI-LO1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a motivated individual to play a critical role in the payroll team. Reporting directly to the Associate Director, Payroll, this position requires a meticulous individual who thrives in a fast-paced environment and has experience in high-volume, deadline-driven payroll operations. This position will work closely with internal stakeholders and external vendors to drive impactful improvements within the Sr. Payroll Specialist area of focus. Key Responsibilities: Perform accurate and timely semi-monthly payroll processing for US employees including special runs such as off-cycle processing using ADP Workforce Now. Work with the HR team regarding payroll related items such as benefit deductions, leave-of-absences, onboarding of new employees, termination of existing employees, and data validation in ADP. Serve as the primary point of contact for payroll-related inquiries and foster a collaborative and high-performance work environment with an open and two-way communication ambience. Assist with new state payroll tax registrations and ensure that Payroll is in compliance with federal, state, and local tax regulations, wage and hour laws and company policies. Analyze payroll data to identify trends, discrepancies and opportunity areas, and provide payroll reports as needed. Handle year-end processes including W2 preparation, process tax amendments and payroll reconciliations. Provide payroll information to auditors, tax firms, and internally as requested. Participate in process improvements and special projects as needed. Required Skills, Experience and Education: Bachelor's Degree in Finance, Accounting or Business with 7+ years of experience in payroll within a public company. Minimum 5+ years of recent hands-on experience with ADP Workforce Now. Working knowledge and deep understanding of the state and federal labor laws and regulations. Ability to work independently, protect and safeguard confidential information, great attention to detail, and able to adapt to changing priorities with a strong focus on quality and accountability. Strong project management skills with the ability to anticipate events, prioritize assignments, deal with interruptions, and meet deadlines in a fast-paced and growth-oriented environment. Excellent written and verbal communication skills that foster a collaborative work environment. Preferred Skills: Experience in Workday and global payroll. Proficient in Microsoft Office including advanced Excel skills with large amounts of data and pivot tables. #LI-Hybrid #LI-YG1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$116,000-$145,000 USD

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. The Senior Project Admin Coordinator, oversees activities for senior leadership, including managing complex calendars, organizing meetings, and arranging travel logistics. They serve as a primary point of contact for various meetings, events, presentations and projects. Key Accountabilities/Core Job Responsibilities: * Confidentially coordinate activities for assigned members of Denali Senior Leadership. This includes management of a complex calendar(s) and organizing BOD, advisory and investor meetings when required. * Coordinate travel arrangements and associated logistics with shifting priorities and deadlines. Plan and organize meetings, prepare agendas, provide research and background information, create presentations and coordinate all logistics. * Represent Senior Leadership to external constituencies by serving as the primary point of contact and assessing requests and questions. Make autonomous, accurate and swift judgments, including forwarding questions and requests to other senior staff. * Prepare Senior Leadership for internal/external meetings by researching organizations and individuals, bringing together resources to aid in preparation, and compiling relevant materials. * Anticipate the business needs for Denali Senior Leadership and senior team by proactively formulating and evaluating solutions and/or recommendations to facilitate meeting deadlines and achieving goals. * Partner and coordinate hiring activities for the Talent Acquisition team, including: * Maintaining a master calendar including, but not limited to candidates, hiring managers and Talent Acquisition staff. * Coordinating travel arrangements and associated logistics, while navigating shifting priorities. * Serving as a central point of contact for assessing requests and questions from candidates interviewing for role in various Denali business areas, and channeling requests to other team members as appropriate. * Compose correspondence. Develop, review, and edit presentations and documentation. Independently research and analyze associated issues and/or compile materials needed for presentation and/or decision-making purposes. * Manage multiple projects simultaneously. Anticipate and track initial dates, events, and associated action items; follow up with appropriate parties on behalf of supervisor to ensure deadlines are met. * Support event planning and execution. * Maintain accurate and timely recording of work time by clocking in and out using designated timekeeping systems. Adherence to company timekeeping policies, including rules regarding overtime, meal breaks, and reporting procedures for any discrepancies. Qualifications/Skills: * High school diploma or equivalent and 4+ years of administrative support experience required * Proven track record of supporting senior-level leadership * Demonstrated ability to handle sensitive issues and maintain the utmost confidentiality * Demonstrated ability to perform duties with a high level of professionalism, flexibility, discretion, judgment, diplomacy, and tact * Exemplary internal and external interpersonal and customer service skills * Ability to multitask, adapt to changing priorities and deadlines * Advanced computer skills and demonstrated experience with office software and G-Suite * Excellent verbal and written communication skills, including editing and proofreading * Growth mindset with interest and curiosity to learn new things * Ability to adapt to changes in a rapidly scaling organization * Excellent planning and organizational skills * Ability to take initiative and ownership of projects Preferred Qualifications * Bachelor's degree * Biotech industry experience * Previous experience working for a global organization Hourly Range: $50.00 to $61.54 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at ****************************************** This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Playing a critical role as a lead statistician for clinical program(s) and studies and the subject matter expert (SME) in Biostatistics within Quantitative Sciences function, this position is to provide statistical leadership and support for clinical development strategy and clinical studies through product life cycle. Provide statistical support and strategic input to clinical development plans and target product profiles, proof of concept criteria, and team's preparation for company governance reviews. Represent Biostatistics function on cross-function teams at program level and serve as a lead statistician for oncology studies Collaborate with various functions on study design and planning, protocol development, statistical analysis plan and analysis specifications. Provide statistical support for study protocol development, analysis plan and specification through direct involvement and/or providing guidance to junior staff. Plan and prepare independent data monitoring committee (DMC), coordinate with independent statistical data analysis center for DMC and study team for periodic DMC reviews. Collaborate with data management and clinical operations over the course of clinical studies to provide statistical input to study conducts and database development as well as data collection and cleaning activities. Collaborate with statistical programming to ensure that appropriate programs and documentations are being developed for datasets development and outputs generation, and ensure the statistical analyses specified in scientific protocols and/or analysis plans are conducted appropriately. Provide statistical input and leadership to the development of global health authority documents, regulatory interaction and response to health authority submissions. Provide statistical support for clinical publications, assist in data interpretation to ensure consistency and accuracy in data presentation. Drive and lead department initiatives, best practices, and guidelines. Keep abreast in new developments in statistics, drug development, and regulatory guidance and share knowledge with functional and cross-functional team members. Required Skills, Experience and Education: D. or M.S. in Statistics/Biostatistics, a minimum of 8 years (for Ph.D.) and 12 years (for M.S.) of experience in the biotech/pharma industry as a statistician. Level will be determined based on the relevance of experience. Hands-on experience in design and analysis of oncology trials is a must. Ability to work independently and within a team. Solid knowledge in ICH and other regulatory requirements related to biostatistical activities and clinical trials. Excellent verbal and written communication skills are required. Good interpersonal and project management skills are essential. Proficiency in SAS and/or R. Preferred Skills: Active participation in NDA/BLA filing through label negotiations desirable. #LI-Hybrid #LI-SH1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$204,000-$255,000 USD

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: In this role, you will work within our Translational Medicine group analyzing and interpreting molecular and clinical data. Analysis will focus on using genomic, protein and other targeted assays to identify and validate predictive biomarkers. The bioinformatician will work on various projects in different phases of drug development and contribute to the cross-functional team, which includes other bioinformaticians, program leads, medical monitors, biostatisticians, and preclinical scientists. As a Scientist II, Clinical Bioinformatics in Translational Medicine, you will: Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA/DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs. Work with internal groups, contract research organizations and collaborators to deliver validated biomarker data and analysis. Support the development of biomarker related aspects of the trial design where bioinformatic analysis is required, including developing and executing on biomarker and statistical analysis plans. Work with biomarker scientists to support analysis of biomarker readouts (summary statistics, and visualization of efficacy in molecular subgroups). Collaborate with preclinical bioinformaticians to design, analyze and interpret experiments to validate biomarkers, understand compound mechanism of action and resistance, and identify biomarkers for patient selection/stratification. Required Skills, Experience and Education: M.S. or Ph.D. in bioinformatics, data science or a related field with emphasis on biological data analysis. 2+ years of pharmaceutical or biotech experience in bioinformatics focused on oncology, or related field. Proficiency and experience programming using R and/or Python. Previous biostats and/or translational medicine experience in phase 3 trials strongly preferred. Proficiency in statistical models and analysis of clinical data. Some ML experience a strong plus. Proficiency in visualizations and faceting of molecular data necessary (oncoplots, heatmaps, PCA, etc.). Experience with efficacy, baseline demographic, and other outcome data generated in a clinical trial. Experience with statistical methods i.e. survival analysis, and causal inference. Expertise in bioinformatic analysis of cancer signaling pathways and driver mutations. Experience in tools to analyze cancer genomics data types (RNA, WES, ct DNA, etc) and common tool outputs (GATK, Salmon, OncoKB, VEP, etc.) preferred. Preferred Skills: Development with professional software development systems and methods (IDEs, git, ticketing systems). Familiarity with large public/private genomic data sets (GDC, TCGA, etc.). Familiarity with clusters, containers, and cloud computing infrastructure for data processing, analysis, and storage. Experience in tools to analyze cancer genomics datasets (GATK, Salmon, OncoKB, VEP, etc.). #LI-Hybrid #LI-SH1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$128,000-$160,000 USD

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Project Coordinator role is essential to execution and achievement of goals and objectives of the US Commercial Field teams providing administrative support and project execution across the leadership and team members including: Provides administrative support across remote field team members in different time zones and project executional support for key field events, activities and initiatives. Leads meeting support managing logistics, room reservations, catering, audio-visual equipment set-up, and assists in creation, preparation, organization and communications of key meeting materials for all field team meetings, trainings and regional/division meetings. Interacts with various stakeholders including field leaders, cross functional business partners and external vendors/ agencies. Establishes processes, timelines and milestones to plan and execute on key field events and initiatives. Plans and coordinates conference attendance and related activities, including conference registration, hotel stays, reception arrangements, catering, and logistics for external events (i.e., speaker series, ad boards, KOL meetings) Plans and coordinates domestic and international travel details including flights, VISA applications, travel documents, car transports, hotel bookings, restaurant reservations and other travel related needs of senior field leaders as needed; this may require evening or weekend support, depending on the travel requirements. Handles recruitment and onboarding activities including all full-time, temporary, and consulting candidate interview scheduling for the functions supported, as well as coordinating 1st day of new hire planning w/HR and hiring manager. Coordinates expense report processing and reconciliation of receipts and credit card statements for senior field leaders as needed. Provides presentation slides support: consolidation, formatting, content organization as requested. Works with Contract Administration team and business partners to coordinate consulting and/or master service agreements in partnership with legal to ensure they are in place and executed properly, including within approval limits, to support functional groups. Fosters an open, inclusive, and collaborative culture within US Commercial function. Partners with Commercialization Operations and Administration team members to find synergies across activities. Required Skills, Experience and Education: Bachelor's degree required with 3+ years of administration experience supporting at the executive level with progressive experience in project management or business operations in biopharma or life sciences. Exhibits impeccable integrity and sound judgment to handle highly sensitive and confidential material and information. Strong organizational, project and time management skills; detail oriented and ability to manage multiple deliverables. Ability to prioritize and multi-task projects and demands effectively. Ability to collaborate with multiple stakeholders across field teams, cross functional partners, and/or external vendors. Willingness to support Revolution Medicines to succeed by thinking outside of the box and job description. Able to adapt to changes in the work environment. Professional demeanor and team-player while maintaining positive, team-focused attitude. Proactive and excellent self-initiative. Excellent verbal and written communication skills. Preferred Skills: Biotechnology experience highly preferred. Proficient with MS Word, Excel, PowerPoint, and Outlook calendar. Experience with applicant tracking systems highly preferred. Experience with project management tools, (i.e. SmartSheet) and communications platforms (i.e., Teams portal development, newsletters) is a plus. #LI-Hybrid #LI-SS2 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$96,000-$120,000 USD

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Director of Medical Writing will be responsible for helping to develop strategic leadership and management of the medical writing function and involves both a people and project-orientated focus. This position reports to the Executive Director, Medical Writing. Required Skills, Experience and Education: Driving for success in terms of people, projects, and productivity of medical writing, including all deliverables in alignment with corporate goals. Assuring the successful completion of high quality, timely and compliant document deliverables. Developing and implementing remediation plans/actions as needed. Providing medical writing leadership and guidance to full-time and contract medical writers. Assisting the Executive Director, Medical Writing, in developing budget and resource requirements for contract medical writers across multiple programs for each fiscal year. Demonstrating current and applied knowledge and understanding of regulatory requirements and standards to ensure consistent application, adherence, and timely achievement of compliant deliverables. Serving as a primary subject matter expert for the planning, design, and preparation of clinical and regulatory documents. Authoring and reviewing clinical regulatory documents as needed, including assisting teams in responding to regulatory requests. Attracting, hiring, and retaining qualified contract medical writing professionals Providing an atmosphere of training, mentorship, and coaching to align with a strategic view of the role of medical writing in clinical development. Working within the medical writing function and cross-functionally to test and develop policies regarding the use of structure content management and/or generative AI as part of clinical regulatory document processes. Structuring resourcing to ensure an effective and cost-efficient approach to covering portfolio workload and goals while ensuring sustainability and alignment with corporate goals. Providing leadership across the medical writing department through strategic input, continual process improvement, and innovation in the development and implementation of a strategic view of regulatory documents. Collaborating and partnering with cross functional leaders and other staff across project management, regulatory affairs, clinical operations, clinical development, biostatistics, and other functions. Representing the medical writing department externally with academic institutions, industry groups/peers, vendors and other entities to develop expertise and drive industry standards and best practice. Doctoral degree and 5 years of regulatory medical writing experience. Master's degree and 7 years of regulatory medical writing experience. Bachelor's degree and 8 years of regulatory medical writing experience. At least 3 years of experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources. Preferred Skills: Academic preparation in life sciences or pharmacy with at least 8 years of related experience in the pharmaceutical/biotechnology industry. Experience in oncology. Strong understanding of drug development process. Experience with authoring major clinical regulatory documents, including protocols and amendments, study reports, and marketing application summaries. Experience with structured content management and/or generative AI use in the medical writing space preferred but not required. #LI-Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range$204,000-$255,000 USD

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the Senior Vice President, Head of Europe, the Vice President, General Manager Italy will lead the expansion efforts across Italy. In a highly competitive environment of Italy, this leadership role is critical to maximizing the opportunity for RevMed innovation to impact patients across Italy. In collaboration with the regional leadership team, the successful catalytic leader will develop and execute commercial and operational strategy to accelerate the engagement with Italy key stakeholders and customers (government authorities, regulatory authorities, payer authorities, KOLs) as well as all necessary constituencies to support expansion into the European region - ensuring that reimbursement and access considerations are integrated in the existing and future clinical program design of the company portfolio / pipeline. The incumbent will be responsible for developing pre-launch and commercialization strategic plans for Italy and providing Italy -specific input into lifecycle plans across the RevMed portfolio. This individual will have full accountability for the Italy P&L, all operations in Italy and will ensure official, fiduciary, and legal and compliance requirements are met locally and for the European region respectively. Responsibilities: Develop and manage the Italian P&L including the budget for operations in Italy, ensuring optimal resource allocation. Develop and execute comprehensive plans for the company's expansion in Italy. As dictated by the commercialization strategy, build and lead the required multifunctional management team, working with corporate functional leaders to ensure that each team member and business function execute against the clear and well-aligned business objectives. Provide Italy-specific input for Regional and Global Clinical Development Plans. Support the Clin Ops team by ensuring appropriate site selection in Italy, quality and enrollment in-line with regulatory/compliance requirements. Co-lead with Finance, Legal, and Commercial, the selection and contract negotiation with any local distributor and Trade 3 rd parties and upon completion of contract, oversee and be accountable for successful execution and achievement of goals by the distributor. Support the effective negotiation of consultant/agency contracts for timely and cost-effective services in various business areas to support pre-launch and launch activities. Lead the Italian Government/Corporate Affairs efforts ensuring the successful execution of global and European strategies, advocating for policies that promote Italy patient access. Cultivate and maintain strategic relationships with government entities, patient organizations, healthcare providers, industry associations, and medical societies through innovative engagement programs. Represent the company in Italian healthcare policy forums and industry associations, collaborate with peers to shape collective positions and advocate for patient centered policies. Support all relevant efforts to ensure the regional and global clinical program designs are informed by the Italian clinical and local/regional market access strategy and dynamics. Work closely with regulatory affairs to secure best and fastest pathways to approvals. Evaluate the competitive environment and understand the profile of portfolio compounds and the patients to serve in order to identify opportunities and challenges in the oncology market across Europe and other key markets. Lead the planning and execution of product launches in Italy, including market access strategies, pricing, disease area and marketing campaigns, and where appropriate, early access programs. Foster a culture with the global team consistent with the global RevMed values and vision/mission. Set key launch and financial performance metrics including revenue, profitability etc. Required Skills, Experience and Education: Advanced degree in life sciences, business administration, or a related field. Proven Italy experience in a leadership role within the biopharmaceutical industry. Fluency in both verbal and written English and Italian; any other major European language is an advantage. Proven track record shaping and executing regional strategy and influencing policy at a senior industry level. In-depth knowledge of the Italy pharmaceutical market and regulatory environment. Oncology, including NSCLC and pancreatic cancer and colorectal cancer related experiences as well as for biomarker/companion diagnostics. Proven experience building and developing a high performing cross-functional team is a must. Organizational and P&L Leadership experience in Italy required. Ability to create and nurture a strong culture of collaboration and authenticity to extend and replicate the RevMed culture. Proven success in building effective relationships with internal stakeholders, regional authorities, and vendors. Highly organized and motivated individual possessing excellent communication, presentation and interpersonal skills. Strong leadership and influencing skills with the ability to create a clear sense of direction. Thrives in a fast-paced, dynamic small company environment and able to roll out the sleeves to get things done. Preferred Skills: Experience with an oncology launch in Italy is desired. Serve as business partners to Development functions. Project Management experience and certification preferred. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a key player in our Cancer Immunology team, you will: Develop, design, conduct and analyze in vitro, in vivo and ex-vivo experiments to characterize novel RAS pathway and other oncogenic pathway-targeted therapies and inform patient selection for monotherapy and combination therapy strategies. Develop in vitro immunological assays to assess the biological functions of candidate drug targets and therapeutic mechanisms in both human and murine primary immune cells and established cell lines. Support cross-functional teams to generate novel insights that fuel drug development and ensure the timely dissemination of critical program data. Stay up to date with relevant technical expertise and latest discoveries in tumor immunology Prepare and deliver clear and accurate scientific presentations for internal meetings and external conferences. Required Skills, Experience and Education: Ph.D. degree in immunology, cancer biology or a related discipline with demonstrable track record of excellence in tumor immunology and/or immunotherapy. Hands-on experience in ‘state of the art' immunology techniques including multi-parameter flow cytometric analyses, cytokine analysis, functional assays with immune cells, cell biology and molecular biology. Comprehensive knowledge of oncogenic signaling pathways, role and function of immune cells in cancer, as well as immunotherapies Self-motivated, independent, rigorous, well-organized experimentalist with a desire to continue in a laboratory-focused role. Excellent written and verbal communication skills. Strong track record of research productivity as evidenced by high-quality, impactful publications. Strong interpersonal and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment. Preferred Skills: Understanding of cancer plasticity and drug tolerance/persistence/resistance is desirable Hands-on experience with mouse models to evaluate the efficacy and mechanisms of action of therapeutic agents; experience with humanized mouse models is desirable The base salary range for this full-time position is $115,000 to $144,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-NE1

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. Denali is seeking an Intern for the Bioprocess Development group in Technical Operations. This position will be a hands-on laboratory position with a focus on optimizing conditions for Chinese Hamster Ovary (CHO) cell lines for expression of complex therapeutic proteins. The candidate will get exposure to suspension cell culture and single use bioreactors. This is an exciting opportunity to get an overview of biologics process development and manufacturing. The intern must be self-driven, organized, collaborative and able to communicate clearly and thrive in a highly dynamic and fast-paced environment. Responsibilities * Work under supervision of Denali scientists to design, execute and interpret cell culture experiments * Perform and analyze shake flask and lab-scale bioreactor fed-batch production experiments * Learn to use cell culture lab instruments such as such as Vi-Cell, Nova Flex2 and Octet * Analyze results and present work to bioprocess development group Requirements * Candidates pursuing a BS or MS in Biology, Chemical Engineering or related field * Familiarity with basic laboratory skills such as pipetting, material weighting, etc. * Previous hands-on lab experience with mammalian cell culture including aseptic techniques is highly desired * Demonstrated ability to organize, analyze and interpret experimental data * Self- and results-driven, organized, resourceful, adaptable and collaborative * Bold and creative thinker with a curious nature, eager to learn about the complexities of the business of healthcare and biotech * Evident communication and analytical skills * High degree of proficiency with the MS Office Suite or Google equivalent The expected wage for this position based on the South San Francisco California office location is $22.11 to $27.40 per hour. Paid holiday time off is based on Denali's designated holidays. Interns who live more than 50 miles away from the office are eligible for an additional housing stipend. Job Facts * Start Date: Summer 2026 * Length of Assignment: 10 - 12 weeks * Location: South San Francisco, CA * Job Type: Paid Internship This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class. This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Temp Director of Regulatory Science (Early Development) is accountable for the delivery of regulatory science and strategy for designated early-stage programs at RevMed. They will support programs and drug development teams and ensure delivery of targeted, pragmatic, well-vetted, consistent and actionable regulatory advice for designated programs. The Director must have a thorough understanding of and be experienced in oncology drug development, applicable regulations, and current health authority thinking, and have strong leadership and relationship-building ability. Independently deliver sound regulatory science and strategy support to early development program teams (pre-IND through EOP1/2) Ensure drug development programs are fully resourced for the applicable stage of development and all relevant regulatory requirements are met Anticipate upcoming work; ensure robust and effective regulatory support. Ensure regulatory science takes account of competitive developments, evolving regulatory guidance, expert feedback, and that advice is aligned with company goals and objectives Ensure regulatory advice, policy and decision-making is consistent across programs and that learnings from one program are fully considered in other programs. Establish highly collaborative and effective relationships with colleagues in Clinical Research, Clinical Operations, Clinical Pharmacology, Nonclinical, Regulatory, Medical Writing, PM, Quality and other functions to ensure cross-functional alignment and team effectiveness. Required Skills, Experience and Education: Degree in life sciences, pharmacy, medicine, or related fields with a minimum of 12 years in the pharmaceutical/biotech industry or relevant work experience and a minimum of 8 years in Regulatory Affairs Demonstrated success in leading early stage regulatory submissions globally (IND, CTA, FDA meeting packages) Direct experience with oncology drug development. Experienced in representing Regulatory on cross functional teams and presenting to senior management. Excellent communicator. Excellent planning and organizational skills and the ability to work simultaneously on multiple projects with tight timelines. Preferred Skills: An advanced degree is desirable. Experience with combination studies, multiple expansion cohort, basket or umbrella and master protocols highly preferred. This is a contract position that will be employed through a third-party recruiting agency. The agency will provide the pay range, which will be based on several factors, including job-related skills, experience, market conditions, and relevant education or training. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a highly motivated and scientifically driven field based and customer facing Director Medical Liaison / Medical Advisor to jump start Medical Affairs activities in Spain. This role will report in the beginning to the SVP Head of Europe until a VP Head of Medical Affairs Europe has joined, and later on to the Senior Medical Director Spain. This position will be instrumental in driving the scientific excellence, clinical insight, and medical strategy supporting our oncology pipeline and marketed products. The field based Director Medical Liaison / Medical Advisor will serve as the medical expert within the upcoming Spanish affiliate, ensuring scientific integrity and alignment with global and European medical affairs and clinical objectives. The position will require close collaboration with cross-functional partners including clinical development, clinical operations, regulatory, commercial, HEOR, market access, and other field medical teams across Europe. Key Responsibilities Develop and implement an early pre-launch Spanish Medical Affairs strategy and tactical plan for assigned products and therapeutic areas. Establish and maintain trusted scientific relationships with key opinion leaders (KOLs), investigators, and healthcare professionals across Spain. Provide medical oversight and scientific input to cross-functional teams, ensuring alignment with regulatory and compliance standards. Collaborate with other Medical Science Liaisons, Medical Affairs, and clinical research departments to support scientific exchange, education, and data dissemination activities. Contribute to medical input in promotional and non-promotional materials, internal training, and advisory boards. Plan and execute national medical meetings, symposia, and congress participation to enhance scientific visibility. Support investigator-initiated trials and local clinical research activities in collaboration with global and regional teams. Monitor the competitive and scientific landscape to inform internal strategy and provide actionable medical insights. Partner with HEOR and market access to develop real-world evidence and outcomes research projects. Ensure compliance with Spanish and EU regulatory frameworks governing interactions with healthcare professionals. Collaborate closely with Clinical Operations and CROs, including site selection, Site Initiation Visits, and investigator engagement Required Skills, Experience and Education: Advanced scientific or medical degree (MD, PharmD, or PhD) required; oncology experience strongly preferred. Minimum 8-10 years of experience in Medical Affairs or related functions in the pharmaceutical or biotech industry. Strong understanding of oncology clinical development, evidence generation, and treatment landscape. Proven ability to interpret and communicate complex scientific and clinical data. Experience engaging with healthcare professionals, academic researchers, and medical societies. Excellent interpersonal, organizational, and presentation skills. Fluency in Spanish and English (written and spoken). Ability to work effectively in a matrixed, cross-functional, and multicultural environment. Willingness to travel nationally and internationally (up to 25%). Preferred Skills: Prior experience in oncology product launches Strong network within the Spanish oncology community. Experience in investigator-initiated or real-world evidence studies. Knowledge of Spanish healthcare systems, reimbursement structures, and compliance requirements. Track record in publication planning, congress presentations, and scientific communications. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Remote #LI-LO1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This is a unique opportunity for a Clinical Trial Management Associate (CTMA). You will be responsible for supporting the execution of clinical activities across vendors, CROs, and sites from start-up through close-out with growing independence. This position will report into the Associate Director, Clinical Operations or Clinical Program Manager. Responsibilities: Work on problems of a moderate scope, using independent decision-making to select course of action within described guidelines under moderate supervision. Serve as Clinical Trial Assistant (CTA) back-up for arranging meeting logistics, agendas, and meeting minutes. Maintain tracking systems (e.g., site status, enrollment metrics); assist with study start-up activities (e.g., site feasibility, essential document collection). Interact with the Clinical Study Execution Team (CSET), as directed, to complete moderate tasks; interface with vendors and site personnel as needed. Ensure document quality and audit readiness in Trial Master File (TMF) with close collaboration with the CTA. With moderate supervision from the study lead (or designee), support the review of study documents such as protocols, informed consent forms (ICFs), case reports forms (CRFs), monitoring plans, etc. Participate in process improvement intiatives limited to your day-to-day scope. Interface with vendors (e.g., central labs, CROs) and site personnel as needed and with limited supervision from the study lead (or designee). Mentor and support CTAs. Support other Clinical Operations activities as appropriate. Required Skills, Experience and Education: BS, BA, or RN in a relevant scientific discipline. 3-5 years of relevant experience in the pharmaceutical or biotech industry, preferably in Clinical Operations or Clinical Research related experience. Intermediate knowledge of FDA and EMA Regulatorions, ICH Guidelines, GCP, and familiarity with standard clinical operating procedures. Good communication and teamwork skills. Proficient in MS Office and project tracking tools. Strong attention to detail and organization, demonstrate reliability and efficiency in supporting clinical trial operations. Take the initiative to independently apply knowledge of Clinical Operations. Thrives in a collaborative team setting that demonstrates flexibility required to maintain a fast pace and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment. High sense of urgency and commitment to excellence in the successful execution of deliverables. Ability to multi-task, prioritize tasks, anticipate challenges, and execute on goals as a member of an interdisciplinary team. Travel may be required (~10%). Preferred Skills: Has familiarity working with vendor systems/portals (e.g., eTMF, EDC, IRT, CTMS). Oncology experience, early and/or late stage, strongly preferred. This is a contract position that will be employed through a third-party recruiting agency. The agency will provide the pay range, which will be based on several factors, including job-related skills, experience, market conditions, and relevant education or training. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Commercialization Contracts Administration Manager is essential to execution and achievement of goals and objectives across the Medical Affairs and Commercial Development functions at Revolution Medicines. This role requires strong process management and execution, compliance management, cross functional and vendor collaboration, process optimization, the ability to thrive in ambiguity, and a passion to build and optimize critical business processes. Execute and manage contracts (SOWs, CDAs, MSAs) through collaboration with Legal/Compliance teams and Business Contract owners across Medical Affairs and Commercial Ensure efficiency and compliance of all contracts with company policies, legal requirements, and industry regulations. Provide training and guidance to new business contract owners on contracting obligations and processes to ensure adherence to legal and compliance standards. Monitor contract lifecycles, including renewals, amendments, and terminations to ensure timely and compliant management. Be the liaison and point of contact for business contract owners and vendor/agency inquiries related to contracting and payment in partnership with legal, finance, and procurement. Manage timely and proactive communications with stakeholders. Maintain contract management system and tracker to manage and prioritize the volume to ensure timely execution and follow through of fully executed contracts to POs. Leverage expertise to drive contract system and process enhancement efforts. Work closely with Commercial Development Operations and Medical Excellence Operations team members to address business needs while optimize contracts administration. Required Skills, Experience and Education: Bachelor's degree required with 3+ years of relevant experience in contracts administrative role (procurement, contract management, or purchasing departments) pharmaceuticals or biopharma industry. Track record of being a collaborative team player and business partner, building positive partnerships and adaptive to meet the needs of a growing business. Strong critical thinker and problem solver with proactive mindset to build and manage processes and systems that drive accountability and results. Demonstrated ability to influence management and key business partners without authority Excellent organizational skills, ability to multi-task, and prioritize effectively to deliver results within reasonably established timelines. Strong interpersonal skills including verbal and written communication and represent Revolution Medicines and embodies our corporate values. Proficient in Powerpoint, Excel, Word, and variety of project management (ie, smartsheets) and communication and administrative platforms (ie, Teams, contracts management system, etc). Preferred Skills: Targeted Oncology product experience preferred. Prior experience working in a fast-paced, matrixed biotech or pharmaceutical environment. Familiarity with emerging digital tools for Medical Affairs and Commercial functions. This is a contract position that will be employed through a third-party recruiting agency. The agency will provide the pay range, which will be based on several factors, including job-related skills, experience, market conditions, and relevant education or training. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-SS2

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the Senior Vice President, Head of Europe, the Vice President General Manager, UK and Ireland will lead the expansion efforts across UK and Ireland. In a highly competitive environment, this leadership role is critical to maximizing the opportunity of RevMed innovation to impact patients in UK and Ireland. In collaboration with the European LT, the successful leader will develop and execute commercialization and operational strategy to engage with key stakeholders (government authorities, regulatory authorities, payer authorities, KOLs) to help secure reimbursement that reflects the value of the innovation. The role will also play a key role in engaging other key constituencies to support expansion into the European region - ensuring that reimbursement and access considerations are integrated in the existing and future clinical program design of the RevMed portfolio / pipeline. The incumbent will be responsible for developing pre-launch and commercialization strategic plans for UK and Ireland and providing UK and Ireland-specific input into lifecycle plans across the RevMed portfolio. This individual will have full accountability for the UK and Ireland P&L, all market operations and will ensure official, fiduciary, and legal and compliance requirements are met locally and for the European region respectively. Responsibilities: Develop and manage the UK and Ireland P&L including the budget for market operations, ensuring optimal resource allocation with appropriate investment gating to key events/triggers. Develop and execute comprehensive plans for the company's expansion in UK & Ireland. As dictated by the commercialization strategy, build and lead the required multifunctional management team, working with corporate functional leaders to ensure that each team member and business function execute against the clear and well-aligned business objectives. Provide UK and Ireland input for Regional and Global Clinical Development Plans and Non-Registrational data generation plans. Support the Clin Ops team by ensuring appropriate UK & Ireland site selection, quality and enrollment in-line with regulatory/compliance requirements. Co-lead with Finance, Legal, and Commercial, the selection and contract negotiation with any local Distributor and Trade 3 rd parties and upon completion of contract, oversee and be accountable for successful execution and achievement of goals by the distributor. Support the effective negotiation of consultant/agency contracts for timely and cost-effective services in various business areas to support pre-launch and launch activities. Lead the UK and Ireland Government/Corporate Affairs efforts ensuring the successful execution of global and European strategies, advocating for policies that promote patient access in UK and Ireland. Cultivate and maintain strategic relationships with government entities, patient organizations, healthcare providers, industry associations, and medical societies through innovative engagement programs. Represent the company in UK and Ireland healthcare policy forums and industry associations, collaborate with peers to shape collective positions and advocate for patient centered policies. Support all relevant efforts to ensure the regional and global clinical program designs are informed by the UK and Ireland clinical and local/regional market access strategy and dynamics. Work closely with regulatory affairs to secure best and fastest pathways to approvals. Evaluate the competitive environment and understand the profile of portfolio compounds and the patients to serve to identify opportunities and challenges in the oncology market across Europe and other key markets. Lead the planning and execution of product launches in UK and Ireland, including market access strategies, pricing, disease area and marketing campaigns, and where appropriate, early access programs. Foster a culture with the global team consistent with the global RevMed values and vision/mission. Set key launch and financial performance metrics including revenue, profitability etc. Required Skills, Experience and Education: Advanced degree in life sciences, business administration, or a related field. Proven UK and Ireland experience in a leadership role within the biopharmaceutical industry. Fluency in both verbal and written English; any other major European language is an advantage. Proven track record shaping and executing regional strategy and influencing policy at a senior industry level. In-depth knowledge of the UK and Ireland pharmaceutical market and regulatory environment. Oncology, including NSCLC and pancreatic cancer and colorectal cancer related experiences as well as for biomarker/companion diagnostics. Proven experience building and developing a high performing cross-functional team is a must. Organizational and P&L Leadership experience in UK and Ireland required. Ability to create and nurture a strong culture of collaboration and authenticity to extend and replicate the RevMed culture. Proven success in building effective relationships with internal stakeholders, regional authorities, and vendors. Highly organized and motivated individual possessing excellent communication, presentation and interpersonal skills. Strong leadership and influencing skills with the ability to create a clear sense of direction. Thrives in a fast-paced, dynamic small company environment and able to roll out the sleeves to get things done. Preferred Skills: Experience with an oncology launch in UK and Ireland is desired. Serve as business partners to Development functions Project Management experience and certification preferred. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and . For additional information, please contact privacy@revmed.com.