REVOLUTION Medicines Jobs

Company: Revolution Medicines (NASDAQ: RVMD) is a publicly-traded, clinical-stage precision oncology company developing novel targeted therapies for RAS-addicted cancers. Its R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. Position Overview: Revolution Medicines is seeking a dynamic Corporate Counsel, Contracts to join the Legal Team. This role will focus on legal contracts, including negotiation of new contracts, interpretation of and compliance with active contracts and development and management of the Company's contract management system. Experience: 5+ years of transactional legal experience, including a combination of in-house and law firm experience, is required. 2+ years of experience in drafting and negotiating contracts at a biotech or life sciences company is preferred. Location: Redwood City, CA preferred. Remote candidates will be considered. Relocation: Yes. This is a national search. Bar: Candidate must be a member in good standing of a U.S. State Bar.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit high-value frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Vice President of Health Economics Outcomes Researcher (HEOR) and Real World Evidence (RWE) is responsible for leading the strategy and execution of programs to assess the clinical and economic impact of healthcare interventions in the real world, with the goal of helping healthcare organizations make informed decisions. As the leader of HEOR and RWE at Revolution Medicines, you will explore and develop novel approaches to high-impact, near-real time value evidence generation throughout the lifecycle of Revolution Medicines' portfolio, and build ongoing professional relationships with healthcare decision makers, public and private payers and policy makers, as well as HEOR researchers. This is an exceptional opportunity to contribute to the advancement of healthcare by providing evidence-based insights that can shape the future of patient care in Oncology. Responsibilities: Develop high-impact HEOR strategy and lead efficient and timely execution of programs supporting the value propositions of Revolution Medicines' portfolio. Ensure HEOR evidence addresses the needs and expectations of key stakeholders such as patients, healthcare providers, payers and Health Technology Assessment (HTA) agencies. Effectively present research findings to internal and external stakeholders to improve internal decision making and to promote wider adoption of research findings across external stakeholders. Develop the value propositions of Revolution Medicines' portfolio, allowing key healthcare and formulary professionals to make informed therapeutic decisions. Collaborate with internal stakeholders including medical affairs, marketing, biostatistics and clinical development teams to ensure that relevant health economics data are integrated into clinical studies and commercialization plans. Engage and collaborate with external partners including payers, health care providers, thought leaders, and decision-makers to establish/maintain strong partnerships and gather insights into research programs. Work closely with cross-functional colleagues to develop integrated evidence plans for oncology disease areas across the portfolio. Explore novel industry-leading approaches to building real-world data platforms that enable fast, efficient and near-real time Real World Evidence (RWE) generation. Promote research efficiency through technology to standardize research processes and enable cumulative research intelligence capabilities. Lead real-world research partnership engagements with leading healthcare, academic and payer organizations to co-create value evidence and help drive evidence-based optimal care. Stay up to date with and add to the advancements in health economics methodologies and best practices. Identify and interface with HEOR & RWE experts and organizations, profile data sources and related organizations as they relate to Revolution Medicines' portfolio and therapeutic areas. Closely monitor new trends in health policy and payer environment, assess competitive data gaps and communicate to the organization, to help Revolution Medicines build industry-leading capabilities and be on the cutting edge of Evidence Based Medicine issues and HEOR data. Lead or contribute to development of Medical and HEOR function through leadership of functional initiatives and change management. Required Skills, Experience and Education: Deep expertise in health economics, outcomes research, patient-reported outcomes or related fields in the biotechnology or pharmaceutical industry. Experience in oncology drug development is highly desirable, especially related to gastrointestinal and thoracic malignancies. Experience building and leading high performing teams. Minimum 15 years of relevant experience with an advanced degree in a relevant field (DrPH, PharmD). Track record of high impact publications in HEOR/RWE topics. Strong written and interpersonal communication skills, with an ability to present complex technical information clearly. Knowledge and experience in managed care, integrated delivery networks, formulary decision-making, and payment/access models. Ability to establish relationships with experts in real world evidence (RWE) and therapeutic areas of interest. Preferred Skills: Advanced, medical/scientific doctoral level degree (PhD or MD). 20+ years experience of relevant experience within Medical Affairs experience. The base salary range for this full-time position is $284,000 to $355,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. #J-18808-Ljbffr

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. The Senior MSL is a field-based representative of the medical affairs team, primarily responsible for advancing scientific and collaborative relationships with key healthcare providers (HCPs) and decision makers within a defined geography via timely knowledge exchange of accurate, scientific, and non-promotional information to enable optimized patient outcomes. Key Accountabilities/Core Job Responsibilities: Identify and develop strong scientific relationships with HCPs within a defined territory and provide credible, and fair-balanced information about Denali's research activities and product development Respond to unsolicited medical and scientific requests for medical information in a compliant and timely manner Provide clinical trial support to identify potential new sites, resolve issues with enrolling sites, and participate in investigator meetings, as appropriate; liaise with R&D, Medical Affairs, and Clinical Operations teams Provide scientific presentations at company sponsored and external meetings, as needed Develop and maintain a high level of therapeutic area, disease state and product expertise Participate in national and regional medical/scientific meetings and symposia to engage with attendees, attend scientific sessions and poster presentations, and gather clinical and business insights to share with internal cross-functional teams. Lead and/or participate in training, and other internal efforts to support medical objectives; may serve as a training lead Appropriately document interactions and act in accordance with company policies and guidelines Qualifications/Skills: Doctorate level degree is required (PharmD or PhD); MD degree preferred Specialty training in rare disease and/or neuroscience preferred 5+ years of relevant work experience, including 3+ years in an MSL role in the in the pharmaceutical/biotech industry Knowledge of current regulatory guidelines to ensure corporate compliance in all activities, including those related to scientific interactions, unsolicited questions and clinical trials and research. Excellent interpersonal and communication skills with the ability to effectively present scientific and medical information to diverse audiences, including HCPs, researchers, payors, patients and industry colleagues. Ability and willingness to travel up to 75% including overnight travel to accomplish field scientific responsibilities. This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. Key Accountabilities/Core Job Responsibilities: Distribution Management: Build and maintain strong partnerships with 3PLs, specialty distributors, specialty pharmacies, and customers. Oversee the performance of distribution partners to ensure efficient and compliant operations including quarterly business reviews (QBRs). Develop strategies to support medicine launches, ensure supply continuity, and address distribution challenges. Data Flow, SAP integration & Reporting: Serve as the Denali commercial representative on its SAP implementation team. Lead the integration and optimization of channel operations workflows within the SAP ERP system, ensuring alignment with commercial, accounting, and gross-to-net processes. Manage inventory, sales, and chargeback data flows to ensure timely and accurate information sharing across stakeholders and systems. Collaborate with and manage outsourced vendors to ensure high-quality data integration, aggregation, analytics, and reporting services. Provide data-driven insights to inform decision-making and support market access strategies. Contract Administration: Administer any contract related payments with 3PLs, specialty distributors, specialty pharmacies and customers. Ensure accuracy and classification of contract-related payments for partners and help ensure data structures and data flows provide for government price reporting accuracy and compliance. Ensure documentation and secure database for all contract related contracts, SOP's, and payments and that customers receive accurate contract pricing. Operational Oversight: Monitor performance metrics and contractual compliance for distribution partners and outsourced vendors. Drive continuous improvement initiatives to optimize the distribution model, contract administration process and enhance efficiencies. Ensure adherence to regulatory requirements and industry standards. Cross-Functional Collaboration: Partner with internal teams, including supply chain, government price reporting lead, commercial, regulatory, and finance, to align distribution activities with organizational goals and help ensure compliance. Serve as a key point of contact for resolving distribution-related issues and fostering teamwork across functions. Contribute as appropriate with technical operations and the supply chain team on all topics that may impact product packaging. Act as a key contact for external auditors, responding to inquiries and data requests, and assisting in resolution of discrepancies. Prepare and maintain audit-ready documentation to support SOX compliance and other regulatory requirements. Qualifications Bachelor's degree in business, supply chain, or related field (MBA or advanced degree preferred). 7+ years of experience in channel operations, distribution, and supply chain within the biopharma or healthcare industry. Experience managing relationships with 3PLs, specialty distributors, and specialty pharmacies. Strong knowledge of data management, including inventory, sales, and chargeback processes. Experience with administering distribution and customer related contracts. Experience with ERP systems including SAP Familiarity with rare disease markets and the unique challenges of patients with rare diseases. Exceptional project management, analytical, and problem-solving skills. Excellent communication and interpersonal skills with a collaborative mindset. Critical Success Factors Flexibility and Agility: Ability to thrive in a fast-paced, efficient environment and manage competing priorities. Strategic and Tactical Balance: Capable of shaping long-term strategies while executing operational details effectively. Team Player: Willingness to collaborate across functions and contribute to a positive, solution-oriented culture. Proactive Mindset: Anticipates challenges, seeks innovative solutions, and takes initiative to improve processes. This is a unique opportunity to play a key role in the success of Denali which is dedicated to making a difference in the lives of patients. Salary Range: $183,000.00 to $232,333.00 . Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at ****************************************** This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a motivated individual to play a critical role in the payroll team. Reporting directly to the Sr. Payroll Manager, this position requires a meticulous individual who thrives in a challenging environment and has experience in high-volume, deadline-driven payroll operations. This position will collaborate closely with internal stakeholders and external vendors to drive impactful improvements within the Sr. Payroll Specialist area of focus. Key Responsibilities: * Perform accurate and timely semi-monthly payroll processing for US employees including special runs such as off-cycle processing using ADP Workforce Now * Work with the HR team regarding payroll related items such as benefit deductions, leave-of-absences, onboarding of new employees, termination of existing employees, and data validation in ADP. * Serve as the primary point of contact for payroll-related inquiries and foster a collaborative and high-performance work environment with an open and two-way communication ambience. * Assist with new state payroll tax registrations and ensure that Payroll is in compliance with federal, state, and local tax regulations, wage and hour laws and company policies. * Analyze payroll data to identify trends, discrepancies, and opportunity areas, and provide payroll reports as needed. * Manage year-end processes including W2 preparation, process tax amendments and payroll reconciliations. * Provide payroll information to auditors, tax firms, and internally as requested. * Participate in process improvements and special projects as needed. Required Skills, Experience and Education: * Bachelor's degree in finance, Accounting or Business with 5+ years of experience in payroll within a public company * Minimum 3+ years of recent hands-on experience with ADP Workforce Now * Working knowledge and deep understanding of the state and federal labor laws and regulations * Ability to work independently, protect and safeguard confidential information, great attention to detail, and able to adapt to changing priorities with a strong focus on quality and accountability. * Strong project management skills with the ability to anticipate events, prioritize assignments, deal with interruptions, and meet deadlines in a fast-paced and growth-oriented environment. * Excellent written and verbal communication skills that foster a collaborative work environment. Preferred Skills: * Experience in Workday and global payroll vendor implementation and integration * Proficient in Microsoft Office including advanced Excel skills with substantial amounts of data and pivot tables. The base salary range for this full-time position is $96,000 to $120,000 for candidates based at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the minimum and maximum salary for the position in Redwood City and will be adjusted for the local market a candidate is based. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-DN1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Playing a critical role as a lead statistician for oncology clinical studies and the subject matter expert (SME) in Biostatistics within Quantitative Sciences function, this position is to serve as a study-level lead statistician and provide statistical leadership and support for clinical development strategy and programs through product life cycle. * Represent Biostatistics function on cross-function teams at study team and serve as a lead statistician for oncology studies. * Collaborate with various functions on study design and planning, protocol development, statistical analysis plan and analysis specifications. * Provide statistical support for study protocol development, analysis plan and specification through direct involvement and/or providing guidance to junior staff. * Plan and prepare independent data monitoring committee (DMC), coordinate with independent statistical data analysis center for DMC and study team for periodic DMC reviews. * Collaborate with data management and clinical operations over the course of clinical studies to provide statistical input to study conducts and database development as well as data collection and cleaning activities. * Collaborate with statistical programming to ensure that appropriate programs and documentations are being developed for datasets development and outputs generation, and ensure the statistical analyses specified in scientific protocols and/or analysis plans are conducted appropriately. * Provide statistical support for clinical publications, assist in data interpretation to ensure consistency and accuracy in data presentation. * Keep abreast in new developments in statistics, drug development, and regulatory guidance and share knowledge with functional and cross-functional team members. Required Skills, Experience and Education: * Ph.D. or M.S. in Statistics/Biostatistics, minimum 4 years (for Ph.D.) and 6 years (for M.S.) of experience in biotech/pharma industry as a statistician. Level will be determined based on the relevance of experience. * Hands-on experience in design and analysis of oncology trials is a must. * Solid knowledge in ICH and other regulatory requirements related to biostatistical activities and clinical trials. * Excellent verbal and written communication skills are required. * Good interpersonal and project management skills are essential. * Proficiency in SAS and/or R. Preferred Skills: * Hands-on experience in design and analysis of phase 3 oncology trials desirable. The base salary range for this full-time position is $180,000 to $225,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-SH1

divp style="text-align:left"Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. /pdivdivdivdivp style="text-align:inherit"/pp style="text-align:left"We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. /p/div/div/div/divp style="text-align:inherit"/pp style="text-align:inherit"/pNeurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. As our discovery and development efforts have matured, we are preparing to launch our first asset in Hunter syndrome, and we invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. br/br/ br/br/The Enzyme Transport Vehicle (ETV) Account Lead role is a field-based role reporting to a Senior Regional Sales Director and is responsible for building and maintaining long term relationships with physicians and other customers to maximize the impact of our innovative portfolio in the Lysosomal Storage Disorder communities we serve. The ETV Account Lead role is empowered to deliver both access and reimbursement support to the accounts within their assigned territory and deliver promotional messages to support and inform product adoption in a compliant manner. This role will be the single accountable individual within their territory representing Denali in educating the MPS II Hunter syndrome community and customers on the approved use of tividenofusp alfa following FDA approval. p style="text-align:inherit"/pp style="text-align:inherit"/pdivdivpbuspan Key Accountabilities/Core Job Responsibilities/span/uspan: /span/b/p/divdivpspan /span/p/divdivpspanspan The ETV Account Lead plays /spanspana central role/spanspan in our cross functional field team, or Local Care Team, and the successful candidate will have a deep /spanspanunderstand/spanspaning/spanspan of both their local healthcare market and of the MPS II disease state. /spanspan To successfully deliver our innovative ETV asset to the MPS II community, establishing trust and collaborating compliantly across Denali's team is essential in order to urgently address the needs of our customers and deliver on Denali's goals. /spanspan The Account Lead will /spanspanbe responsible for/spanspan delivering on Denali's business /spanspanobjectives/spanspan through /spanspanstrategic account plan execution and /spanspanagility in adapting to each unique customer's needs. /span/spanspan /span/p/divdivpspan /span/p/divdivpbspan Market and MPS II Knowledge:/span/bspan /span/p/divdivullipspanspan Profile accounts to gather insights, understand HCO decision making/spanspan,/spanspan and inform marketing and targeting strategies/span/spanspan /span/p/li/ul/divdivullipspanspan Identify/spanspan and track potential HCPs treating MPS II patients /spanspanto /spanspanunderstand specific drivers, barriers, and opportunities to support these customers/span/spanspan /span/p/li/ul/divdivpbspan Account Planning/spanspan:/span/bspan /span/p/divdivullipspanspan Collaborate with peers, Local Care Team members, and field leadership to /spanspand/spanspanevelop and execute strategic account plans which align to business strategy and deliver an exceptional customer experience/span/spanspan /span/p/li/ul/divdivullipspanspan Build and adjust tactical plans that meet our customers' needs and deliver on our brand strategy and business /spanspanobjectives/spanspan, collaboratively with field and brand leadership/span/spanspan /span/p/li/ul/divdivullipspanspan Develop a launch day engagement plan to deliver tailored strategies and tactics for HCO readiness/span/spanspan /span/p/li/ul/divdivullipspanspan Establish a post-launch call plan, including customer visit schedules aligned to territory and account plans/span/spanspan /span/p/li/ul/divdivpbspan Customer Engagement:/span/bspan /span/p/divdivullipspanspan Communicate disease state awareness and education to elevate the urgency /spanspanto appropriately treat MPS II /span/spanspan /span/p/li/ul/div/divdivdivullipspanspan Compliantly educate HCPs and MPS II multidisciplinary care team members on /spanspantividenofusp/spanspan alfa efficacy, safety, and dosing through approved material/spanspans and messaging/span/spanspan /span/p/li/ul/divdivullipspanspan Compliantly educate HCPs and office staff on /spanspantividenofusp/spanspan alfa access process and /spanspanassociated /spanspanpayer polic/spanspanies/span/spanspan /span/p/li/ul/divdivullipspanspan Educate on Denali's patient support services/spanspan and offerings/span/spanspan /span/p/li/ul/divdivullipspanspan Partner with all Denali field roles to d/spanspaneliver an exceptional customer experience /spanspanthrough a solution-oriented mindset /spanspanwhich prioritizes the Hunter syndrome patient and family/spanspan /spanspanexperience/span/spanspan /span/p/li/ul/divdivullipspanspan Participate in conferences/spanspan,/spanspan scientific meetings/spanspan, and community events/spanspan to engage with and educate HCPs on MPS II disease state and /spanspantividenofusp/spanspan alfa post launch/span/spanspan /span/p/li/ul/divdivpbspan Denali Engagement:/span/bspan /span/p/divdivullipspanspan Participate in field meetings and training programs to understand disease state, brand strategy messaging and /spanspanobjectives/spanspan, and payer landscape, /spanspanpolicies/spanspan and reimbursement trends/span/spanspan /span/p/li/ul/divdivullipspanspan Timely completion of all corporate, compliance and /spanspan HCP /spanspanengagement policy training to ensure /spanspanappropriate customer/spanspan interactions and alignment with Denali values/span/spanspan /span/p/li/ul/divdivullipspanspan Collaborate compliantly with peers and Local Care Team field members /span/spanspan /span/p/li/ul/divdivullipspanspan Appropriately share insights and learnings with leadership, marketing, /spanspaninsights/spanspan and operations to contribute to evolving strategy/span/spanspan /span/p/li/ul/divdivp/ppbuspan Qualifications/Skills/span/uspan: /span/b/p/divdivullipspanspan Bachelor's /spanspan Degr/spanspanee and /spanspan7/spanspan+ years of relevant experience/span/spanspan or /spanspanspan Master's Degree and 5/spanspan+ years of relevant experience preferred /span/spanspan /span/p/li/ul/divdivullipspanspan5/spanspan+ /spanspan Years of /spanspancustomer-facing experience /span/spanspan /span/p/li/ul/divdivullipspanspan Rare disease experience; MPS experience preferred/span/spanspan /span/p/li/ul/divdivullipspanspan Track record/spanspan of successful launch experience, and proven /spanspantrack record/spanspan for meeting or exceeding targets/span/spanspan /span/p/li/ul/divdivullipspanspan Reimbursement and access education and support experience/span/spanspan /span/p/li/ul/divdivullipspanspan Fluency in healthcare ecosystem and payer knowledge/span/spanspan /span/p/li/ul/divdivullipspanspan Highly collaborative and self-driven mindset/span/spanspan /span/p/li/ul/divdivullipspanspan Passion for patients and mission-driven work/span/spanspan /span/p/li/ul/div/divdivdivullipspanspan Excellent communication and analytical skills /span/spanspan /span/p/li/ul/div/divp style="text-align:inherit"/pp style="text-align:inherit"/pp style="text-align:inherit"/pp style="text-align:left"span This/spanspan compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. This compensation and benefits information is based on Denali's good faith estimate as of the date of publication and may be modified in the future. /spanbr /br/pp style="text-align:left"span Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class. /span/pp style="text-align:inherit"/pp style="text-align:inherit"/p/div

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: In this role, you will work for 8-12 weeks within our Translational Medicine group to develop methods for identifying potential prognostic/predictive biomarkers for our RAS(ON) inhibitors. The primary focus will be on next-generation sequencing (NGS) data (RNA-seq, WES, etc.) from patient samples enrolled in our ongoing clinical trials. During this internship, the student will be mentored by a senior computational biologist and work closely with other members of the biomarker group. Required Skills, Experience and Education: * Currently enrolled in a graduate program (PhD, MS, MPH, etc.) focused on bioinformatics, data science, statistics, epidemiology, or life sciences with computational component. * Proficiency in R (preferred) and/or Python programming languages. * Experience with genetics and/or NGS data. * High motivation, desire to learn, and enthusiasm. Preferred Skills: * Experience in one or more of the following areas is preferred: computational biology (e.g. bulk/single cell RNA-seq), cancer genetics, statistical modeling, and/or clinical data. The base salary range for this intern position is $32.75 to $35.00 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking an enthusiastic and highly motivated intern to assist our Quality Assurance (QA) Compliance team. This role will engage with and support multiple areas of RevMed's Quality Management System (QMS). Our goal is that this internship will provide broader perspective of the QA function in product development and oversight, as well as exposure to cross-functional teams and stakeholder engagement. This position will report to the Manager, Quality Compliance. This opportunity will include: * Supporting KPI (key performance indicator) and KQI (key quality indicator) metric development. * Running periodic reports to monitor metrics and sharing with QA and sub-functional teams. * Building reporting tools, such as meeting slide decks, pre-read materials, etc. * Assisting with organizing GxP supplier management related documentation. * Performing administrative activities in Veeva Quality Platforms (electronic Document Management System and electronic Learning Management System). * Other tasks as assigned by management. Required Skills, Experience and Education: * Must be currently enrolled in a full-time undergraduate or graduate degree program at an accredited University, with interest an in Life Sciences, Pharmaceutical Sciences, Engineering, or a related field. * Excellent written and verbal communication and interpersonal skills. * Demonstrate ability to multi-task and prioritize tasks. * Disciplined time management and organizational skills. Preferred Skills: * Have a basic understanding of pharmaceutical development and regulatory requirements. * Experience working in Microsoft Word, Excel, PowerPoint, and Outlook. * Creative-thinker open to learning across a range of topics. * Strong desire to learn from and work with various QA team members. The base salary range for this intern position is $32.75 to $35.00 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a Clinical Trial Assistant II in Clinical Operations, initially reporting to the Director Clinical Operations, you will be responsible for acting as a central contact for the clinical study teams and assist with the clinical execution and management to support RevMed clinical trials. Specifically, you will be responsible for: * Assisting in the development, review, distributing, and archiving of study specific documents and reports (plans, training materials, study guides, manuals, etc.) * Assisting with updating and maintaining clinical systems and any reporting tools. * Set up and maintenance of the trial master files (TMF) if applicable, or work with CRO to audit and resolve discrepancies. * Create, maintain, and track information for key study related activities. * Assisting in the preparation of meeting materials, scheduling meetings, and developing agendas, taking meeting minutes for internal clinical operation team meetings * Gathering investigator and site information, to support study start-up, maintenance and close out activities. * Working with cross functional study teams, and vendors to assist in the coordination of clinical trial activities. * Support other clinical operations activities as appropriate. Required Skills, Experience and Education: * Bachelor's degree in biological sciences or related health related field required. * 1 - 3 years of relevant experience in the pharmaceutical or biotech industry. * Thrives in a collaborative team setting and driven by a desire to deploy innovative approaches and technologies in a high-energy environment. * Excellent written and verbal communication skills. * Demonstrate proficiency in Microsoft Word, Excel and PowerPoint and other software platforms. * Demonstrated ability to multi-task, prioritize options. * Travel up to (~25%). Preferred Skills: * Preferably in clinical operations or clinical research-related experience. * Experience in oncology clinical trials. The base salary range for this full-time position is $75,000 to $90,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-DN1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As part of the Toxicology group in the Department of Nonclinical Development and Clinical Pharmacology (NDCP), the Toxicology Intern will collaborate with RevMed toxicologists to support development of safety studies using new bioengineered tissue models and informatics tools to help advance the preclinical safety assessment of RevMed molecules. This internship will provide an opportunity to interact with scientists in a team-driven environment. * Reviewing study reports and data files, and extracting relevant data obtained from complex in vitro and in vivo toxicology studies. * Leading or overseeing safety studies while collaborating with RevMed teams or external vendors. * Collating, analyzing and interpreting data from across toxicology studies and different disciplines (such as gene expression, cell biology, PK) using various software analytical tools. Required Skills, Experience and Education: * Interest in chemistry/toxicology and experience designing experiments in fields related to neurobiology, systems biology and/or tissue bioengineering. * Proficiency with MS Office suite and Smartsheets. * Experience using various data analytics and statistical software to acquire, store, transform, and visualize data, such as Prism, or by coding using R, Python, etc. * Ability to identify issues and seek solutions. Preferred Skills: * Ability to work both independently and collaboratively. * Efficient, organized, and able to handle short timelines in a fast-paced environment. * Ability to identify issues and seek solutions. The base salary range for this temporary position is $32.75 to $35.00 for candidates based at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the minimum and maximum salary for the position in Redwood City and will be adjusted for the local market a candidate is based. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: * Upholding the core values at Revolution Medicines: i) Tireless Commitment to Patients; ii) Transformative Science; iii) Exceptional Together; iv) Total Integrity; and v) Inclusiveness and Fairness. * Programming lab automation instruments and robotics to increase efficiency in lab processes. * Assist in designing, prototyping, and testing lab automation robotics and equipment. * Assist in the setup, calibration, and maintenance of lab automation equipment. * Collect, analyze, and interpret data generated from automated processes. * Collaborate with scientists and research team members to optimize automation protocols. * Maintain accurate records of experiments and results. Required Skills, Experience and Education: * Basic understanding of laboratory techniques and procedures. * Proficiency in programming languages such as Python, R, or JavaScript. * Strong analytical and problem-solving skills. Preferred Skills: * Familiarity with using CAD software like Solidworks or Fusion 360. * Familiarity with lab automation equipment is a plus. The base salary range for this intern position is $32.75 to $35.00 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This is an exciting, high-profile, and highly visible Program Management opportunity to advance first-in-Class RAS(ON) Inhibitors through clinical development. The ideal candidate is a very proficient and self-motivated program manager with a solid understanding of drug development. The Associate Director (AD) acts as a connector across the program ensuring clarity of roles and responsibilities, decision making and accountability for deliverables. They routinely partner with the Lead Program Management and Sub-Team Leaders to translate program strategy into an efficient execution plan. They understand the objectives of the program team and the roles of sub-team members to facilitate productive discussions and decision-making. The AD manages cross-functionally to achieve program milestones. They also play a pivotal role in communications, making sure that teams have access to accurate and timely information regarding program decisions, assumptions, expectations and timelines. Overall, the AD is responsible for program execution at the sub-team level. They not only care about the outcomes but how we get there. The successful candidate will draw upon their experience to: * Understand the program strategy, stakeholders and interdependencies and works with sub-teams to develop set priorities and execute against their plans. * Manage the integrated project plan and project assumptions (accounting for goals, key objectives, deliverables, risks) to enable accurate project, financial and portfolio analyses for business planning processes. * Identify critical path activities, resource constraints, risks, and conflicts that could impact the timelines or budget; work with subject matter experts to construct appropriate mitigation plans. * Contribute to scenario planning (comprising costs, timelines, risks, and project strategy) to inform stage gate, portfolio, budget and long-range planning. * Manage the preparation, review, editing and submission of project documents, presentations and communications. * Lead an efficient information flow within the project team and sub-teams,and prepare materials and reports for internal advisory and governance meetings. * Practice effective meeting and information management including, timely meeting agendas and minutes. * Facilitate project team meetings, follow up on action items, document meeting materials and decisions, and act as a primary contact for project team related information. * Partner with the sub-team leads to ensure the team achieves and maintains a high-level of sustainable performance. Identify and resolve issues related to efficient and effective team operation. * Recommend and implement opportunities for streamlining team and business processes. * Drive adoption of project management systems and best practices across the program team. * Onboard and train new team members on program structure, relevant stakeholders and program management resources (team site, project plan, RAID log, meeting calendar, etc.). * Support new programs and special projects as needed. Required Experience, Skills, and Education: The Ideal candidate will have the following experience and be able to demonstrate the following: * B.A. or BSc. in Life Sciences and at least 5 years' experience in the biotech/pharmaceutical industry with at least 2 years' direct development project management experience managing cross-functional development teams. * Understanding of the clinical drug development process and regulations, coupled with strong proficiency in project management practices, tools, and methodology. * Expertise in developing and managing project scope, deliverables, risk & resource requirements including, schedule / timeline management, and risk management. * Excellent interpersonal skills, including clear, succinct, and timely communication and proven ability to foster important relationships with key stakeholders. * Outstanding verbal and written communication skills with the ability to summarize complex information into simple concepts; has the ability to effectively interact across team line functions as well as with external key stakeholders. * Proven track record of good decision making and exercising sound judgment. * Experience using Project Management software to manage project timelines and resources (e.g., MS Project, SmartSheet, OfficeTimeline, and OnePager Pro etc.). * Strong computer proficiency with MS Office suite, SharePoint and similar document archiving systems. Preferred Skills: * MSc. or MBA or Ph.D. a plus. * PMP (Project Management Professional) or other PM certification or equivalent is a plus. * Experience in Oncology therapeutic area is strongly preferrable. The base salary range for this full-time position is $180,000 to $225,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-YG1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As part of the Clinical Pharmacology group in the Department of Nonclinical Development and Clinical Pharmacology (NDCP), the Quantitative Pharmacology Intern will have the opportunity to interact with scientists in DMPK and Toxicology. The intern will work directly with clinical data, applying quantitative analysis to support decision-making in drug development. The primary goal of the internship is to develop a tumor growth inhibition (TGI) model for the lead clinical compounds at RevMed, addressing key questions about the impact of dose modification and alternative dosing schedules on clinical efficacy. Required Skills, Experience and Education: * Solid PK/PD knowledge with strong modeling and simulation experience using Monolix, S-ADAPT, ADAPT 5, or NONMEM. * Ability to use R for data wrangling and plotting * The candidate must be at least in the 3rd year of a full-time PhD degree program at an accredited university. Preferred Skills: * Ability to work independently and collaboratively. * Prior experience with TGI models. The base salary range for this intern position is $32.75 to $35.00 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-AP1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a member of the Translational Research team within the Biology Department, you will: * Contribute to cutting-edge translational research with unique RAS pathway inhibitors. * Conduct experiments and work cross-functionally to discover and develop novel anti-cancer agents, including but not restricted to: * Cell culture and in vitro experiments * Cancer model development and anti-tumor activity testing of agents. * Collect and process tissue samples for ex vivo analysis. * Analyze experimental data and present results at internal meetings. As a member of RVMD Research team you will have opportunity to collaborate extensively with biologists, chemists, pharmacologists, and data scientists to generate novel insights into key drivers of RAS-addicted cancers and receive hands-on training in various techniques commonly used in preclinical pharmacology studies. Duration will be 5-6 months. Required Skills, Experience and Education: * Current undergraduate or graduate student in biosciences, biochemistry, pharmacology or a related field. * Completed general coursework in Biology, Biochemistry, Molecular Biology, Cell Biology etc. * Demonstrated experience in executing and interpreting data from lab experiments. * Detail-oriented with excellent record keeping and organizational skills. * Enthusiasm for learning new techniques and applying them to benefit cancer patients. Preferred Skills: Prior laboratory experience in a relevant research area would be an advantage, such as: * Hands-on experience with small rodent, molecular and cell biology techniques. * Background in cancer biology and signal transduction research. The base salary range for this full-time position is $33.00 to $35.00 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-DNI

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior R&D Systems Administrator will be responsible for the management and day-to-day administration of our application platforms supporting Research & Development. The ideal candidate will have strong skills and experience in managing both validated and non-GxP SaaS platforms, and a strong understanding of COTS platforms supporting life science research activities. As the primary administrator and escalation point for our R&D systems, this person must possess strong technical and communication skills with the ability to anticipate, triage and resolve problems. This person will be a key member of the Information Sciences Team, reporting directly to the VP of R&D Information Operations. Key responsibilities include: * Administer, maintain, and troubleshoot platforms supporting Research & Development. * Onboard new employees, provide training, and author documentation. * Facilitate user access and permissions to GxP and non-GxP R&D platforms. * Build and maintain close relationships with key stakeholders. * Plan, communicate, and deploy changes to R&D platforms following standard change management processes and scheduled maintenance windows. * Coordinate change and maintenance activities with business stakeholders. * Review and update software administrative SOPs. * Maintain data integrity, including performing assessments, periodic reviews, and disaster recovery per FDA guidelines and company SOPs. * Ensure compliance by maintaining system integrity within strict regulatory frameworks including 21 CFR Part 11 and GxP standards. * Support validation and change control activities and related documentation for new functionality and upgrades to controlled systems. Required Skills, Experience and Education: * Bachelor's degree or equivalent and a minimum of 7 years in the delivery of technology services and support in a GxP regulated environment, including experience in pharma, life sciences or a related industry. * Advanced knowledge of industry guidelines (GAMP 5) and US and international regulations (FDA, ICH, ISO, EU) for GxP regulated environments. * Knowledge and experience with Computer System Validation and 21 CFR Part 11. * Strong knowledge of security access controls, policies, groups, rights, and permissions. * Efficient time management, adept at managing multiple projects simultaneously. * Strong written and verbal communication, presentation, and facilitation skills. Ability to distill complex information to effectively present to senior leadership. * Strong customer service skills, with the ability to work effectively in a dynamic and fast-paced environment. * Experience with applications supporting life science research and development. * Experience administering validated Enterprise level platforms supporting regulated workflows in Quality, Regulatory, CMC and Clinical Operations. Preferred Skills: * Experience managing ServiceNow workflows and automation. * Experience administering Veeva Vault platforms such as Quality Docs, QMS & RIMS. * Experience administering a CTMS system such as eClinical eluminate. * Experience with Cloud platforms, particularly AWS and Azure. * Experience with ERP Supply Chain/Inventory platforms such as NetSuite. The base salary range for this full-time position is $158,000 to $198,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-YG1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: * Serve as Revolution Medicines' primary business operation lead and project management interface between internal PDM functions and Contract Research Development Manufacturing Organization (CRDMOs) for drug substance, including raw materials, key starting materials, and regulatory starting materials by providing adequate oversight. * Establish and maintain mutually beneficial long-term business relations with CRDMOs. * Lead contract negotiations in close collaboration with cross-functional team (Subject Matter Experts (SMEs) and Legal) to ensure best terms and conditions. * Support preparation and execution of CRDMOs business reviews with PDM senior management and business counterparts. * Support development and implementation of outsourcing strategies for PDM. * Drive the selection process for CRDMOs in collaboration with technical SMEs. * Ensure projects/programs meet desired results, compliance, speed, quality, and cost. * Support development of scope of work (SOW) in close collaboration with technical SMEs. * Support cross-functional CRDMO management activities, covering all aspects such as business needs identification, market screening, contracting, vendor qualification and set-up, compliant delivery of services, and discontinuation. * Support management of CRDMO budget, purchase orders, and invoices. * Work with PDM senior management and cross-functional teams to assess and manage supplier performance through use of personal influence, internal business review meetings, and/or joint governance meetings. * Identify and deliver on cost savings opportunities. Required Skills, Experience and Education: * B.Sc. or M.Sc. in scientific field with 8+ years of experience in pharmaceutical strategic sourcing and/or supply chain. * Experience working with domestic and international CRDMOs. * Experience managing both strategic and tactical/operational projects. * Working knowledge of and experience in clinical manufacturing, regulatory, QA, and cGMP requirements for small molecules. * Working knowledge of small molecule drug development and commercialization, including, but not limited to, raw material and starting material sourcing, API/drug substance manufacturing, process development, process engineering, and process characterization. * Working knowledge of pharma end-to-end supply chain. * Strong negotiation skills. * Solid project management, facilitation, and problem-solving skills. * Solid organizational and time management skills. * Effective, open, and transparent communication skills (verbal and written) * Capable of working on multiple projects/tasks and able to meet timelines. * Self-starter with a high-level of comfort with ambiguity and complexity and the ability to multi-task while consistently delivering quality results. * Team-oriented, progressive thinker who enjoys participating in an innovative and creative work environment. Preferred Skills: * Experience in implementing and/or managing inventory management system. * Working knowledge of commercial manufacturing. * Experience developing, negotiating, and executing clinical or commercial supply and/or quality agreements. The base salary range for this full-time position is $180,000 to $225,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-CT1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Playing a critical role as the subject matter expert (SME) of Drug Product team within the Pharmaceutical Development and Manufacturing (PDM) function, the position will be responsible for drug product development and manufacturing with focused on formulation and process optimization, clinical batch production, scale-up development and process validation in support of RevMed pipeline compounds development and eventual commercialization. Responsibilities: * Support drug product development and manufacturing activities to advance new chemical entities (NCEs) from clinical development to commercialization. * Support and/or lead formulation and process development, clinical manufacturing, scale-up, technology transfer, process validation and packaging of solid oral drug products at CDMOs. * Manage GMP manufacturing of drug products to support clinical studies, stability, and process validation, including production timeline, raw materials inventory, etc. * Prepare, review, and approve manufacturing batch records, campaign reports, development study protocols and reports. Perform data review of batch records and summarize batch production history. Assist preparation of CMC regulatory submission documents. * Support and manage process development studies using a quality-by-design approach. Study and identify critical quality attributes and critical process parameters for drug product. Explore and establish proven acceptable range and control strategy for drug product manufacturing. * Collaborate with cross-functional teams, including but not limited to Clinical Supply, Quality Assurance, Analytical Development and QC, Drug Substance, Project Management, Regulatory Affairs, and Research team, to achieve project goals in a timely manner. * Travel to CRO/CDMO sites for the oversight of development and manufacturing activities (up to 10%). Required Experience, Skills and Education: * A graduate degree in Pharmaceutical Science, Chemistry, Chemical Engineering, or related field is desirable. * Preferably MS with 5+ years or PhD with 2+ years of experience in the pharmaceutical/biotech industry with drug product development and manufacturing experience of small molecules. * Experience in formulation and process development, DOE study, technology transfer, process scale-up, clinical manufacturing and primary packaging of solid oral drug products. * Familiar with pharmaceutical analytical techniques to support drug product development and manufacturing. * Knowledge and understanding of current ICH guidelines, GMP regulations, quality systems, and related industry practices for pharmaceutical development. * Working experience in managing development and manufacturing activities at CDMOs. * Excellent communication (both verbal and technical) and problem-solving skills. * Ability to multi-task and thrive in a fast-paced innovative environment. Preferred Skills: Experience in enabling formulation development, spray dried dispersion, roller compaction, tablet compression, and coating are preferred. The base salary range for this full-time position is $128,000 to $160,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-CT1

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This is a unique opportunity for a Clinical Operations Professional who has technical expertise in supporting Phase I-III clinical trials in an industry setting and a strong knowledge of clinical operations, Good Clinical Practice (GCP) and U.S. Food and Drug Administration (FDA) regulatory requirements. Oncology experience preferred. The Clinical Trial Management Associate of Clinical Operations, this role will report to the Sr. Director of Clinical Operations. Specifically, you will be responsible for: * Clinical operations functional activities related to the execution of assigned clinical trials based upon department and corporate goals and objectives. * May assist in the selection, coordination, and management of CROs or vendor relations. * Partners with Clinical Program Manager (CPM) in the review of protocols, informed consents, case report forms, monitoring plans, or clinical study reports. * Interfaces with individuals in other functional areas to address routine study issues. * Reviewing monitoring reports and other study documentation as required. * Oversight of the collection and management of clinical trial documentation to be filed in the Trial Master File (TMF). * Following up on assigned team action items and identification, escalation, and resolution of issues as needed. * Assessment of adequacy/feasibility of potential clinical investigators and sites including evaluating facilities, personnel, patient referral base, and adherence to GCP. * Managing investigational product accountability and reconciliation process Assists in the review of routine data surveillance, coordination of the review of data listings and preparation of interim and final clinical study reports and resolution of data discrepancies. * Providing clinical trial support, guidance, and direction to Clinical Trial Assistant(s) (CTAs) assigned to clinical studies. * Preparation and tracking of study participant enrollment projections vs. actuals and study budgets. Required Skills, Experience and Education: * Direct experience of running early-stage clinical trials within an industry environment. * Experience of clinical trial operations outside the USA is desirable, but not essential. * Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials. * Experience in selection of CROs/ vendors and management of external resources. * A demonstrable record of strong vendor management and teamwork. * Direct experience of managing clinical CROs. * Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment. * Excellent written and verbal communication skills. * Demonstrated ability to multi-task, prioritize options, anticipate challenges, and execute goals as a member of an interdisciplinary team is extremely important. * Ability to travel (~25%). Preferred Skills: * BS or MS degree with a minimum of 3 years clinical operations experience in the pharmaceutical or biotech industry, preferably the majority in oncology drug development * Oncology experience, early and/or late stage * Knowledge of MS Suite, Smartsheet * Understanding of EMEA/APAC region(s) clinical trial operations. The base salary range for this full-time position is $87,000 to $104,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. #LI-Hybrid #LI-DN1