Explore jobs
Find specific jobs
Explore careers
Explore professions
Best companies
Explore companies
The average salary for a Clinical Operations Manager stands at $96,262 annually, translating to approximately $46 per hour. Salaries can vary significantly based on factors such as location, experience, and industry. For instance, states like California and New York typically offer higher salaries due to the higher cost of living and increased demand for healthcare professionals.
Entry-level Clinical Operations Managers can expect to earn less than those with several years of experience. For example, professionals with 1-3 years of experience earn around $75,000, while those with over 10 years can make upwards of $120,000.
This role is essential in ensuring the smooth operation of clinical trials and patient care protocols. Many Clinical Operations Managers find opportunities in hospitals, clinical research organizations, and pharmaceutical companies. As the healthcare industry evolves, the demand for skilled professionals in this field continues to grow, making it a promising career choice.
Let Zippia find your next clinical operations manager job
Let Zippia find your next clinical operations manager job
| Experience level | Avg. salary | Hourly rate |
|---|---|---|
| Entry-level clinical operations manager | $39,600 | $19.06 |
| Mid-level clinical operations manager | $61,200 | $29.44 |
| Senior-level clinical operations manager | $111,000 | $53.38 |
The highest-paying states for clinical operations managers are Massachusetts, California, and New York. The lowest average clinical operations manager salary states are Wyoming, Arkansas, and Mississippi.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Rhode Island | $111,052 | $53.39 |
| 2 | District of Columbia | $121,790 | $58.55 |
| 3 | Washington | $103,409 | $49.72 |
| 4 | Maine | $93,743 | $45.07 |
| 5 | Pennsylvania | $96,180 | $46.24 |
| 6 | New York | $115,460 | $55.51 |
| 7 | Maryland | $115,153 | $55.36 |
| 8 | Massachusetts | $125,219 | $60.20 |
| 9 | Connecticut | $103,852 | $49.93 |
| 10 | New Jersey | $113,078 | $54.36 |
| 11 | California | $121,269 | $58.30 |
| 12 | Delaware | $107,390 | $51.63 |
| 13 | Wisconsin | $88,148 | $42.38 |
| 14 | Minnesota | $92,776 | $44.60 |
| 15 | Nevada | $89,540 | $43.05 |
| 16 | Virginia | $105,737 | $50.84 |
| 17 | Arizona | $87,895 | $42.26 |
| 18 | South Dakota | $87,197 | $41.92 |
| 19 | Indiana | $75,683 | $36.39 |
| 20 | Georgia | $77,745 | $37.38 |
| 21 | Texas | $77,268 | $37.15 |
| 22 | Michigan | $79,927 | $38.43 |
| 23 | Colorado | $87,550 | $42.09 |
| 24 | Oregon | $75,431 | $36.26 |
| 25 | North Carolina | $81,224 | $39.05 |
| 26 | Ohio | $74,557 | $35.84 |
| 27 | Utah | $71,405 | $34.33 |
| 28 | New Hampshire | $81,973 | $39.41 |
| 29 | Illinois | $78,354 | $37.67 |
| 30 | Alabama | $76,215 | $36.64 |
| 31 | Missouri | $77,496 | $37.26 |
| 32 | Alaska | $83,869 | $40.32 |
| 33 | Idaho | $72,645 | $34.93 |
| 34 | Louisiana | $68,859 | $33.11 |
| 35 | Tennessee | $67,512 | $32.46 |
| 36 | West Virginia | $71,271 | $34.26 |
| 37 | Vermont | $76,975 | $37.01 |
| 38 | Kansas | $66,846 | $32.14 |
| 39 | North Dakota | $74,143 | $35.65 |
| 40 | Iowa | $69,550 | $33.44 |
| 41 | Florida | $60,786 | $29.22 |
| 42 | Montana | $64,515 | $31.02 |
| 43 | Nebraska | $69,032 | $33.19 |
| 44 | New Mexico | $70,345 | $33.82 |
| 45 | Wyoming | $62,179 | $29.89 |
| 46 | Hawaii | $53,411 | $25.68 |
| 47 | South Carolina | $65,005 | $31.25 |
| 48 | Kentucky | $54,125 | $26.02 |
| 49 | Arkansas | $61,460 | $29.55 |
| 50 | Oklahoma | $64,707 | $31.11 |
| 51 | Mississippi | $61,302 | $29.47 |
The highest-paying cities for clinical operations managers are San Francisco, CA, Boston, MA, and Washington, DC.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | San Francisco, CA | $128,962 | $62.00 |
| 2 | Boston, MA | $125,717 | $60.44 |
| 3 | Washington, DC | $122,038 | $58.67 |
| 4 | New York, NY | $115,770 | $55.66 |
| 5 | Annapolis, MD | $115,284 | $55.42 |
| 6 | Trenton, NJ | $112,649 | $54.16 |
| 7 | Hartford, CT | $104,174 | $50.08 |
| 8 | Seattle, WA | $104,039 | $50.02 |
| 9 | Philadelphia, PA | $96,785 | $46.53 |
| 10 | Rochester, MN | $93,204 | $44.81 |
| 11 | Carson City, NV | $92,651 | $44.54 |
| 12 | Phoenix, AZ | $88,887 | $42.73 |
| 13 | Colorado Springs, CO | $87,709 | $42.17 |
| 14 | Madison, WI | $87,317 | $41.98 |
| 15 | Raleigh, NC | $83,541 | $40.16 |
| 16 | Schaumburg, IL | $78,880 | $37.92 |
| 17 | Atlanta, GA | $78,030 | $37.51 |
| 18 | Dallas, TX | $77,832 | $37.42 |
| 19 | Bend, OR | $75,618 | $36.35 |
| 20 | Indianapolis, IN | $75,369 | $36.24 |
A clinical operations manager's salary ranges from $63,000 a year at the 10th percentile to $146,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $146,000 | $12,167 | $70 |
| 75th Percentile | $120,000 | $10,000 | $58 |
| Average | $96,262 | $8,022 | $46 |
| 25th Percentile | $77,000 | $6,417 | $37 |
| 10th Percentile | $63,000 | $5,250 | $30 |
The highest paying types of clinical operations managers are director of clinical operations, senior operations manager, and technical operations manager.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Manager, Center Operations | $61,059 | $5,088 | $29.36 | 419,533 |
| Clinical Director | $96,497 | $8,041 | $46.39 | 83,232 |
| General Manager Of Operations | $89,522 | $7,460 | $43.04 | 382,581 |
| Director Of Clinical Operations | $130,421 | $10,868 | $62.70 | 151,054 |
| Customer Service/Operations Manager | $69,350 | $5,779 | $33.34 | 249,856 |
| Operations Support Manager | $79,730 | $6,644 | $38.33 | 376,894 |
Top companies hiring clinical operations managers now:
Clinical operations manager salaries at Mayo Clinic and Genentech are the highest-paying according to our most recent salary estimates. In addition, the average clinical operations manager salary at companies like Natera and Fred Hutch are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Mayo Clinic | $161,716 | $77.75 |
| 2 | Genentech | $142,545 | $68.53 |
| 3 | Natera | $135,457 | $65.12 |
| 4 | Fred Hutch | $129,905 | $62.45 |
| 5 | Bristol-Myers Squibb | $128,667 | $61.86 |
| 6 | Merck | $126,078 | $60.61 |
| 7 | Foundation Medicine | $125,279 | $60.23 |
| 8 | Clinica Sierra Vista | $123,863 | $59.55 |
| 9 | Veeva Systems | $123,705 | $59.47 |
| 10 | Alnylam Pharmaceuticals | $123,385 | $59.32 |
| 11 | Excellus BCBS | $122,789 | $59.03 |
| 12 | Moderna | $122,398 | $58.85 |
| 13 | Johnson & Johnson | $121,118 | $58.23 |
| 14 | Seattle Cancer Care Alliance | $120,667 | $58.01 |
| 15 | Presbyterian | $120,479 | $57.92 |
| 16 | Takeda Pharmaceuticals U.S.A., Inc. | $120,305 | $57.84 |
| 17 | Stanford University | $119,992 | $57.69 |
| 18 | RWJBarnabas Health | $118,973 | $57.20 |
| 19 | Medstar Health | $118,805 | $57.12 |
| 20 | Dean Health Plan | $117,463 | $56.47 |
The average clinical operations manager salary has risen by $7,894 over the last ten years. In 2014, the average clinical operations manager earned $88,368 annually, but today, they earn $96,262 a year. That works out to a 4% change in pay for clinical operations managers over the last decade.
Compare clinical operations manager salaries for cities or states with the national average over time.
Compare clinical operations manager salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $96,300 | $46.28 | +2.8% |
| 2024 | $93,600 | $45.00 | -0.1% |
| 2023 | $93,700 | $45.07 | +0.5% |
| 2022 | $93,300 | $44.83 | +1.1% |
| 2021 | $92,200 | $44.34 | +1.6% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| Memorialcare | MGR, Clinical Operations (RN)-or Miller | Long Beach, CA | 06/29/2025 | $158,018 |
| Dignity Health | Manager Clinic Operations | Phoenix, AZ | 06/28/2025 | $89,094 |
| Adapt for Life | Operations Manager-ABA Therapy Clinic-WKY Pay Benefits Day 31! | Orland Park, IL | 06/28/2025 | $65,000 |
| El Camino Hospital Mountain View | Clinical Manager--Days-Pre-Op/Pacu Unit @ MV | Mountain View, CA | 06/27/2025 | $190,668 |
| Humana Inc. | RN Clinical Operations Manager, Home Health | Bluffton, SC | 06/26/2025 | $77,200 |
| Centerwell Home Health | RN Clinical Operations Manager, Home Health | Bluffton, SC | 06/25/2025 | $77,200 |
| Vivie | Manager of Home Health Clinical Operations | Baxter, MN | 06/24/2025 | $80,000 |
| Johnson & Johnson | Clinical Operations Manager | Jacksonville, FL | 06/22/2025 | $115,000 |
| Aurora Health Care | Manager, Clinic Practice Operations | Chicago, IL | 06/22/2025 | $90,367 |
| Discovery ABA | ABA Clinic Operations Manager | Charlotte, NC | 06/22/2025 | $55,000 |
Search for clinical operations manager jobs