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Clinical operations manager salary

Average clinical operations manager salary

$96,262

$46.28 hourly rate

Entry-level clinical operations manager salary
$63,000 yearly salary
Updated December 15, 2025

Understanding the Clinical Operations Manager Salary

The average salary for a Clinical Operations Manager stands at $96,262 annually, translating to approximately $46 per hour. Salaries can vary significantly based on factors such as location, experience, and industry. For instance, states like California and New York typically offer higher salaries due to the higher cost of living and increased demand for healthcare professionals.

Salary by Experience Level

Entry-level Clinical Operations Managers can expect to earn less than those with several years of experience. For example, professionals with 1-3 years of experience earn around $75,000, while those with over 10 years can make upwards of $120,000.

Career Opportunities

This role is essential in ensuring the smooth operation of clinical trials and patient care protocols. Many Clinical Operations Managers find opportunities in hospitals, clinical research organizations, and pharmaceutical companies. As the healthcare industry evolves, the demand for skilled professionals in this field continues to grow, making it a promising career choice.

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Where can a Clinical Operations Manager earn more?

Compare salary by location
Vs
145k
125k
105k
85k
65k
45k
Columbus, OH$128,962
Indianapolis, IN$75,369
Compare salary by company
Vs
187k
167k
147k
127k
107k
87k
Mayo Clinic$161,716
Dean Health Plan$117,463

Clinical operations manager salaries by experience level

Experience levelAvg. salaryHourly rate
Entry-level clinical operations manager$39,600$19.06
Mid-level clinical operations manager$61,200$29.44
Senior-level clinical operations manager$111,000$53.38

Clinical operations manager salary estimates from across the web

Based on the latest salary information compiled by Zippia, Indeed, Glassdoor, Ziprecruiter, Comparably and Payscale, the average salary for a clinical operations manager typically falls between $63,895 and $126,008.
zippia
$96,262yearly
glassdoor[1]
$112,035yearly
indeed[2]
$63,895yearly
comparably[3]
$126,008yearly
ZipRecruiter[4]
$98,039yearly
payscale[5]
$88,197yearly

Average clinical operations manager salary by state

The highest-paying states for clinical operations managers are Massachusetts, California, and New York. The lowest average clinical operations manager salary states are Wyoming, Arkansas, and Mississippi.

  • State view
  • County view
Average salary:

Highest paying states for clinical operations managers

RankStateAvg. salaryHourly rate
1Rhode Island$111,052$53.39
2District of Columbia$121,790$58.55
3Washington$103,409$49.72
4Maine$93,743$45.07
5Pennsylvania$96,180$46.24
6New York$115,460$55.51
7Maryland$115,153$55.36
8Massachusetts$125,219$60.20
9Connecticut$103,852$49.93
10New Jersey$113,078$54.36
11California$121,269$58.30
12Delaware$107,390$51.63
13Wisconsin$88,148$42.38
14Minnesota$92,776$44.60
15Nevada$89,540$43.05
16Virginia$105,737$50.84
17Arizona$87,895$42.26
18South Dakota$87,197$41.92
19Indiana$75,683$36.39
20Georgia$77,745$37.38
21Texas$77,268$37.15
22Michigan$79,927$38.43
23Colorado$87,550$42.09
24Oregon$75,431$36.26
25North Carolina$81,224$39.05
26Ohio$74,557$35.84
27Utah$71,405$34.33
28New Hampshire$81,973$39.41
29Illinois$78,354$37.67
30Alabama$76,215$36.64
31Missouri$77,496$37.26
32Alaska$83,869$40.32
33Idaho$72,645$34.93
34Louisiana$68,859$33.11
35Tennessee$67,512$32.46
36West Virginia$71,271$34.26
37Vermont$76,975$37.01
38Kansas$66,846$32.14
39North Dakota$74,143$35.65
40Iowa$69,550$33.44
41Florida$60,786$29.22
42Montana$64,515$31.02
43Nebraska$69,032$33.19
44New Mexico$70,345$33.82
45Wyoming$62,179$29.89
46Hawaii$53,411$25.68
47South Carolina$65,005$31.25
48Kentucky$54,125$26.02
49Arkansas$61,460$29.55
50Oklahoma$64,707$31.11
51Mississippi$61,302$29.47

Highest paying cities for clinical operations managers

The highest-paying cities for clinical operations managers are San Francisco, CA, Boston, MA, and Washington, DC.

RankCityAvg. salaryHourly rate
1San Francisco, CA$128,962$62.00
2Boston, MA$125,717$60.44
3Washington, DC$122,038$58.67
4New York, NY$115,770$55.66
5Annapolis, MD$115,284$55.42
6Trenton, NJ$112,649$54.16
7Hartford, CT$104,174$50.08
8Seattle, WA$104,039$50.02
9Philadelphia, PA$96,785$46.53
10Rochester, MN$93,204$44.81
11Carson City, NV$92,651$44.54
12Phoenix, AZ$88,887$42.73
13Colorado Springs, CO$87,709$42.17
14Madison, WI$87,317$41.98
15Raleigh, NC$83,541$40.16
16Schaumburg, IL$78,880$37.92
17Atlanta, GA$78,030$37.51
18Dallas, TX$77,832$37.42
19Bend, OR$75,618$36.35
20Indianapolis, IN$75,369$36.24

Clinical operations manager salary details

A clinical operations manager's salary ranges from $63,000 a year at the 10th percentile to $146,000 at the 90th percentile.

Average clinical operations manager salary graph
Average clinical operations manager salary graph, trends, and summary

What is a clinical operations manager's salary?

PercentileAnnual salaryMonthly salaryHourly rate
90th Percentile$146,000$12,167$70
75th Percentile$120,000$10,000$58
Average$96,262$8,022$46
25th Percentile$77,000$6,417$37
10th Percentile$63,000$5,250$30

Highest paying clinical operations manager jobs

The highest paying types of clinical operations managers are director of clinical operations, senior operations manager, and technical operations manager.

Job titleAnnual salaryMonthly salaryHourly rateJob openings
Manager, Center Operations$61,059$5,088$29.36419,533
Clinical Director$96,497$8,041$46.3983,232
General Manager Of Operations$89,522$7,460$43.04382,581
Director Of Clinical Operations$130,421$10,868$62.70151,054
Customer Service/Operations Manager$69,350$5,779$33.34249,856
Operations Support Manager$79,730$6,644$38.33376,894

Top companies hiring clinical operations managers now:

  1. Mayo Clinic jobs (6)
  2. Children's National Medical Center jobs (9)
  3. Covance jobs (7)
  4. Parexel International jobs (12)
  5. PRA Group Careers jobs (9)

Which companies pay clinical operations managers the most?

Clinical operations manager salaries at Mayo Clinic and Genentech are the highest-paying according to our most recent salary estimates. In addition, the average clinical operations manager salary at companies like Natera and Fred Hutch are highly competitive.

RankCompanyAverage salaryHourly rate
1Mayo Clinic$161,716$77.75
2Genentech$142,545$68.53
3Natera$135,457$65.12
4Fred Hutch$129,905$62.45
5Bristol-Myers Squibb$128,667$61.86
6Merck$126,078$60.61
7Foundation Medicine$125,279$60.23
8Clinica Sierra Vista$123,863$59.55
9Veeva Systems$123,705$59.47
10Alnylam Pharmaceuticals$123,385$59.32
11Excellus BCBS$122,789$59.03
12Moderna$122,398$58.85
13Johnson & Johnson$121,118$58.23
14Seattle Cancer Care Alliance$120,667$58.01
15Presbyterian$120,479$57.92
16Takeda Pharmaceuticals U.S.A., Inc.$120,305$57.84
17Stanford University$119,992$57.69
18RWJBarnabas Health$118,973$57.20
19Medstar Health$118,805$57.12
20Dean Health Plan$117,463$56.47

Wage gap by gender, race and education

$100,000$98,000$96,000$94,000$92,000$90,000
MaleFemale

Clinical operations manager salary trends

The average clinical operations manager salary has risen by $7,894 over the last ten years. In 2014, the average clinical operations manager earned $88,368 annually, but today, they earn $96,262 a year. That works out to a 4% change in pay for clinical operations managers over the last decade.

Compare clinical operations manager salaries for cities or states with the national average over time.

Average clinical operations manager salary over time

Compare clinical operations manager salaries for individual cities or states with the national average.

Clinical operations manager salary by year

YearAvg. salaryHourly rate% Change
2025$96,300$46.28+2.8%
2024$93,600$45.00-0.1%
2023$93,700$45.07+0.5%
2022$93,300$44.83+1.1%
2021$92,200$44.34+1.6%

Recently added clinical operations manager salaries

CompanyJobLocationDate addedSalary
MemorialcareMGR, Clinical Operations (RN)-or MillerLong Beach, CA06/29/2025$158,018
Dignity HealthManager Clinic OperationsPhoenix, AZ06/28/2025$89,094
Adapt for LifeOperations Manager-ABA Therapy Clinic-WKY Pay Benefits Day 31!Orland Park, IL06/28/2025$65,000
El Camino Hospital Mountain ViewClinical Manager--Days-Pre-Op/Pacu Unit @ MVMountain View, CA06/27/2025$190,668
Humana Inc.RN Clinical Operations Manager, Home HealthBluffton, SC06/26/2025$77,200
Centerwell Home HealthRN Clinical Operations Manager, Home HealthBluffton, SC06/25/2025$77,200
VivieManager of Home Health Clinical OperationsBaxter, MN06/24/2025$80,000
Johnson & JohnsonClinical Operations ManagerJacksonville, FL06/22/2025$115,000
Aurora Health CareManager, Clinic Practice OperationsChicago, IL06/22/2025$90,367
Discovery ABAABA Clinic Operations ManagerCharlotte, NC06/22/2025$55,000

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