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As of October 2025, the average salary for a Clinical Physician Assistant is approximately $145,549 per year or $70 per hour. Salaries vary significantly based on factors such as geographic location, years of experience, and the healthcare specialty. For instance, Clinical Physician Assistants in states like California and New York typically earn higher wages compared to those in less populated regions.
These variations indicate that location plays a critical role in salary determination. Additionally, Clinical Physician Assistants with advanced certifications or those working in specialized fields such as surgery or emergency medicine often command higher salaries.
With the increasing demand for healthcare services, opportunities for Clinical Physician Assistants continue to grow. The job outlook is positive, with many healthcare facilities seeking skilled professionals. Explore job openings on platforms like Zippia to find positions that align with your career goals.
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The highest-paying states for clinical physician assistants are Minnesota, Massachusetts, and Vermont. The lowest average clinical physician assistant salary states are Missouri, Tennessee, and Louisiana.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Vermont | $169,199 | $81.35 |
| 2 | Massachusetts | $169,849 | $81.66 |
| 3 | Connecticut | $160,206 | $77.02 |
| 4 | Maine | $150,503 | $72.36 |
| 5 | Minnesota | $174,833 | $84.05 |
| 6 | Alaska | $157,538 | $75.74 |
| 7 | Michigan | $152,631 | $73.38 |
| 8 | Nebraska | $167,945 | $80.74 |
| 9 | West Virginia | $144,483 | $69.46 |
| 10 | New Mexico | $146,136 | $70.26 |
| 11 | New York | $153,031 | $73.57 |
| 12 | North Carolina | $153,760 | $73.92 |
| 13 | Nevada | $155,325 | $74.68 |
| 14 | Arizona | $146,826 | $70.59 |
| 15 | Arkansas | $148,277 | $71.29 |
| 16 | Ohio | $145,581 | $69.99 |
| 17 | North Dakota | $139,912 | $67.27 |
| 18 | Wisconsin | $143,652 | $69.06 |
| 19 | Kentucky | $141,724 | $68.14 |
| 20 | Pennsylvania | $142,979 | $68.74 |
| 21 | Maryland | $151,628 | $72.90 |
| 22 | New Jersey | $154,900 | $74.47 |
| 23 | Indiana | $136,119 | $65.44 |
| 24 | South Dakota | $132,507 | $63.71 |
| 25 | Iowa | $138,259 | $66.47 |
| 26 | Illinois | $143,932 | $69.20 |
| 27 | Washington | $139,158 | $66.90 |
| 28 | District of Columbia | $156,689 | $75.33 |
| 29 | Delaware | $140,206 | $67.41 |
| 30 | Virginia | $142,988 | $68.74 |
| 31 | Montana | $130,538 | $62.76 |
| 32 | Wyoming | $133,325 | $64.10 |
| 33 | Mississippi | $137,887 | $66.29 |
| 34 | Hawaii | $144,643 | $69.54 |
| 35 | Kansas | $130,488 | $62.73 |
| 36 | Rhode Island | $138,890 | $66.77 |
| 37 | Colorado | $134,904 | $64.86 |
| 38 | Florida | $122,417 | $58.85 |
| 39 | Texas | $128,628 | $61.84 |
| 40 | New Hampshire | $129,892 | $62.45 |
| 41 | Oregon | $134,093 | $64.47 |
| 42 | California | $143,383 | $68.93 |
| 43 | Oklahoma | $127,773 | $61.43 |
| 44 | Louisiana | $115,746 | $55.65 |
| 45 | Utah | $131,444 | $63.19 |
| 46 | Tennessee | $116,841 | $56.17 |
| 47 | Georgia | $120,154 | $57.77 |
| 48 | Missouri | $120,059 | $57.72 |
| 49 | South Carolina | $114,944 | $55.26 |
| 50 | Alabama | $108,065 | $51.95 |
| 51 | Idaho | $102,280 | $49.17 |
The highest-paying cities for clinical physician assistants are Duluth, MN, Burlington, VT, and Boston, MA.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Duluth, MN | $205,747 | $98.92 |
| 2 | Burlington, VT | $187,521 | $90.15 |
| 3 | Boston, MA | $185,301 | $89.09 |
| 4 | Durham, NC | $163,030 | $78.38 |
| 5 | Syracuse, NY | $162,681 | $78.21 |
| 6 | Grand Rapids, MI | $160,299 | $77.07 |
| 7 | Phoenix, AZ | $155,235 | $74.63 |
| 8 | Santa Cruz, CA | $153,979 | $74.03 |
| 9 | Akron, OH | $153,631 | $73.86 |
| 10 | Chicago, IL | $151,419 | $72.80 |
| 11 | Philadelphia, PA | $148,009 | $71.16 |
| 12 | Seattle, WA | $147,509 | $70.92 |
| 13 | Iowa City, IA | $146,123 | $70.25 |
| 14 | Sioux Falls, SD | $141,084 | $67.83 |
| 15 | Indianapolis, IN | $140,074 | $67.34 |
| 16 | Salem, OR | $139,810 | $67.22 |
| 17 | Galveston, TX | $134,869 | $64.84 |
| 18 | Murray, UT | $133,915 | $64.38 |
| 19 | Saint Louis, MO | $125,164 | $60.17 |
| 20 | Tampa, FL | $123,289 | $59.27 |
A clinical physician assistant's salary ranges from $84,000 a year at the 10th percentile to $252,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $252,000 | $21,000 | $121 |
| 75th Percentile | $194,000 | $16,167 | $93 |
| Average | $145,549 | $12,129 | $70 |
| 25th Percentile | $109,000 | $9,083 | $52 |
| 10th Percentile | $84,000 | $7,000 | $40 |
The highest paying types of clinical physician assistants are certified registered nurse anesthetist, physician assistant student, and certified physician assistant.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Staff Nurse | $68,342 | $5,695 | $32.86 | 699,636 |
| Registered Nurse | $73,349 | $6,112 | $35.26 | 646,159 |
| Registered Nurse Charge Nurse | $71,342 | $5,945 | $34.30 | 645,134 |
| Operating Room Nurse | $68,255 | $5,688 | $32.82 | 545,487 |
| Intensive Care Unit Nurse | $79,483 | $6,624 | $38.21 | 611,699 |
| School Nurse | $54,998 | $4,583 | $26.44 | 282,124 |
Top companies hiring clinical physician assistants now:
Clinical physician assistant salaries at Central Ohio Primary Care and Mayo Clinic are the highest-paying according to our most recent salary estimates. In addition, the average clinical physician assistant salary at companies like Billings Clinic and Grand Itasca Clinic & Hospital are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Central Ohio Primary Care | $239,406 | $115.10 |
| 2 | Mayo Clinic | $224,422 | $107.90 |
| 3 | Billings Clinic | $213,501 | $102.64 |
| 4 | Grand Itasca Clinic & Hospital | $204,288 | $98.22 |
| 5 | Eli Lilly and Company | $203,626 | $97.90 |
| 6 | Fairview Health Services | $199,370 | $95.85 |
| 7 | Bristol-Myers Squibb | $197,980 | $95.18 |
| 8 | Lawrence Memorial Hospital | $197,145 | $94.78 |
| 9 | HealthPartners | $196,607 | $94.52 |
| 10 | Allegheny Health Network | $194,727 | $93.62 |
| 11 | Stanford Health Care | $192,839 | $92.71 |
| 12 | Froedtert Hospital | $191,009 | $91.83 |
| 13 | Mercy Corps | $190,373 | $91.53 |
| 14 | Unm Medical Group, Inc. | $189,989 | $91.34 |
| 15 | UTMB HEALTHCARE SYSTEMS | $189,895 | $91.30 |
| 16 | Mid-Columbia Medical Center | $189,099 | $90.91 |
| 17 | Northwell Health | $188,001 | $90.39 |
| 18 | St. Tammany Health System | $184,913 | $88.90 |
| 19 | Columbia University in the City of New York | $182,521 | $87.75 |
| 20 | Northwestern Medicine | $182,434 | $87.71 |
The average clinical physician assistant salary varies across industries:
| Rank | Industry | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Non Profits | $178,316 | $85.73 |
| 2 | Health Care | $148,309 | $71.30 |
| 3 | Education | $136,789 | $65.76 |
| 4 | Insurance | $123,396 | $59.33 |
The average clinical physician assistant salary has risen by $33,717 over the last ten years. In 2014, the average clinical physician assistant earned $111,832 annually, but today, they earn $145,549 a year. That works out to a 14% change in pay for clinical physician assistants over the last decade.
Compare clinical physician assistant salaries for cities or states with the national average over time.
Compare clinical physician assistant salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $146,000 | $69.98 | +2.7% |
| 2024 | $142,000 | $68.08 | +3.3% |
| 2023 | $137,000 | $65.86 | +3.5% |
| 2022 | $132,000 | $63.59 | +3.2% |
| 2021 | $128,000 | $61.54 | +3.3% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| John Muir Health | Nurse Practitioner or Physician Asst.-PN Cardiology Clinic-Concord--Days | Concord, CA | 06/30/2025 | $181,319 |
| Aurora Health Care | Nurse Practitioner or Physician Assistant-GI-Good Hope and East Mequon Clinics | Milwaukee, WI | 06/28/2025 | $112,281 |
| Ithaca College | Program Director, Clinical Assistant/Associate Professor, Physician Assistant Studies | Ithaca, NY | 06/27/2025 | $155,000 |
| Prime Healthcare Services | Advanced Practice Nurse (APN) or Physician Assistant (PA-C)-Cardiology Clinic | Chicago, IL | 06/27/2025 | $110,000 |
| M3 Usa | Clinical Research Physician-Neurologist- | Las Vegas, NV | 06/27/2025 | $271,310 |
| Staff and Faculty | Clinical Assistant Professor-Physician Assistant Program | Ithaca, NY | 06/27/2025 | $116,000 |
| Northwestern Medicine | Nurse Practitioner or Physician Assistant-Oncology Triage Clinic, , Days | Chicago, IL | 06/26/2025 | $125,220 |
| Department of Veterans Affairs | Physician Assistant-Impact Clinic | Lebanon, PA | 06/26/2025 | $110,702 |
| Massachusetts Eye and Ear Associates, Inc. | Physician Assistant ENT Clinic-Specialty-MEE | Mashpee, MA | 06/26/2025 | $120,000 |
| Ageless Mens Health | Clinic Director-Physician Assistant (PA-C) or Nurse Practitioner (NP) | Peachtree City, GA | 06/26/2025 | $139,000 |
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