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A Physician Assistant (PA) in Internal Medicine plays a crucial role in diagnosing and treating patients under the supervision of physicians. As of October 2025, the average annual salary for this position stands at $125,736, translating to about $60 per hour. Salaries can vary significantly depending on geographical location, years of experience, and specific medical settings.
Compensation for Physician Assistants reflects their expertise and the demand for healthcare services. Factors such as urban versus rural settings can also impact salary levels. For instance, PAs working in metropolitan areas often earn more due to higher living costs and demand for healthcare professionals.
Top-paying states for Physician Assistants in Internal Medicine include California, New York, and Texas, with average salaries exceeding $130,000. Major cities like San Francisco and New York City also offer attractive salary packages. Understanding these dynamics helps you target regions and employers that align with your career goals.
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The highest-paying states for physician assistants, internal medicine are Vermont, Massachusetts, and Connecticut. The lowest average physician assistant, internal medicine salary states are Missouri, Oklahoma, and Tennessee.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Vermont | $158,148 | $76.03 |
| 2 | New York | $145,605 | $70.00 |
| 3 | Connecticut | $146,503 | $70.43 |
| 4 | Massachusetts | $157,219 | $75.59 |
| 5 | Wisconsin | $138,161 | $66.42 |
| 6 | Maine | $138,106 | $66.40 |
| 7 | Alaska | $141,773 | $68.16 |
| 8 | Minnesota | $140,716 | $67.65 |
| 9 | Nevada | $135,524 | $65.16 |
| 10 | New Jersey | $140,595 | $67.59 |
| 11 | Pennsylvania | $127,943 | $61.51 |
| 12 | Nebraska | $137,980 | $66.34 |
| 13 | Michigan | $135,678 | $65.23 |
| 14 | West Virginia | $126,700 | $60.91 |
| 15 | North Carolina | $133,206 | $64.04 |
| 16 | New Mexico | $120,546 | $57.95 |
| 17 | California | $141,339 | $67.95 |
| 18 | Arizona | $125,192 | $60.19 |
| 19 | Maryland | $136,002 | $65.39 |
| 20 | Ohio | $127,533 | $61.31 |
| 21 | Rhode Island | $124,939 | $60.07 |
| 22 | District of Columbia | $145,457 | $69.93 |
| 23 | New Hampshire | $116,628 | $56.07 |
| 24 | North Dakota | $114,004 | $54.81 |
| 25 | Illinois | $121,993 | $58.65 |
| 26 | Indiana | $114,125 | $54.87 |
| 27 | Virginia | $126,550 | $60.84 |
| 28 | Hawaii | $118,774 | $57.10 |
| 29 | South Dakota | $105,316 | $50.63 |
| 30 | Oregon | $116,789 | $56.15 |
| 31 | Kentucky | $116,691 | $56.10 |
| 32 | Delaware | $125,100 | $60.14 |
| 33 | Washington | $118,224 | $56.84 |
| 34 | Texas | $114,878 | $55.23 |
| 35 | Montana | $105,378 | $50.66 |
| 36 | Iowa | $111,634 | $53.67 |
| 37 | Arkansas | $113,692 | $54.66 |
| 38 | South Carolina | $92,506 | $44.47 |
| 39 | Wyoming | $104,042 | $50.02 |
| 40 | Mississippi | $104,610 | $50.29 |
| 41 | Utah | $103,162 | $49.60 |
| 42 | Oklahoma | $90,260 | $43.39 |
| 43 | Louisiana | $88,340 | $42.47 |
| 44 | Colorado | $103,296 | $49.66 |
| 45 | Kansas | $98,213 | $47.22 |
| 46 | Florida | $92,032 | $44.25 |
| 47 | Georgia | $91,486 | $43.98 |
| 48 | Tennessee | $89,437 | $43.00 |
| 49 | Missouri | $90,714 | $43.61 |
| 50 | Alabama | $80,421 | $38.66 |
| 51 | Idaho | $81,731 | $39.29 |
The highest-paying cities for physician assistants, internal medicine are Medford, MA, Modesto, CA, and Bridgeport, CT.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Medford, MA | $163,919 | $78.81 |
| 2 | Modesto, CA | $150,915 | $72.56 |
| 3 | Bridgeport, CT | $149,407 | $71.83 |
| 4 | New York, NY | $149,015 | $71.64 |
| 5 | Rochester, MN | $144,895 | $69.66 |
| 6 | Madison, WI | $138,671 | $66.67 |
| 7 | Holland, MI | $133,982 | $64.41 |
| 8 | Pittsburgh, PA | $124,655 | $59.93 |
| 9 | Chicago, IL | $124,330 | $59.77 |
| 10 | Cincinnati, OH | $122,621 | $58.95 |
| 11 | Medford, OR | $121,530 | $58.43 |
| 12 | Fargo, ND | $119,113 | $57.27 |
| 13 | Arlington, TX | $111,513 | $53.61 |
| 14 | Jeffersonville, IN | $110,340 | $53.05 |
| 15 | Billings, MT | $106,366 | $51.14 |
| 16 | Cheyenne, WY | $104,102 | $50.05 |
| 17 | Highlands Ranch, CO | $103,423 | $49.72 |
| 18 | Mount Pleasant, SC | $92,529 | $44.49 |
| 19 | Macon, GA | $90,364 | $43.44 |
| 20 | Dothan, AL | $79,478 | $38.21 |
A physician assistant, internal medicine's salary ranges from $76,000 a year at the 10th percentile to $207,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $207,000 | $17,250 | $100 |
| 75th Percentile | $163,000 | $13,583 | $78 |
| Average | $125,736 | $10,478 | $60 |
| 25th Percentile | $96,000 | $8,000 | $46 |
| 10th Percentile | $76,000 | $6,333 | $37 |
The highest paying types of physician assistants, internal medicine are pain management physician, obstetrics gynecology physician, and physician extender.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Optometrist | $187,654 | $15,638 | $90.22 | 20,993 |
| Speech Pathologist | $62,640 | $5,220 | $30.12 | 22,779 |
| Family Nurse Practitioner | $100,541 | $8,378 | $48.34 | 41,710 |
| Nurse Practitioner | $100,033 | $8,336 | $48.09 | 27,912 |
| Obstetrics Gynecology Physician | $253,219 | $21,102 | $121.74 | 47,501 |
| Pain Management Physician | $253,724 | $21,144 | $121.98 | 109,196 |
Top companies hiring physician assistants, internal medicine now:
Physician assistant, internal medicine salaries at Mayo Clinic and Maine Health/maine Mental Health Partners are the highest-paying according to our most recent salary estimates. In addition, the average physician assistant, internal medicine salary at companies like Montefiore Mount Vernon Hospital and Memorial Healthcare System are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Mayo Clinic | $188,874 | $90.80 |
| 2 | Maine Health/maine Mental Health Partners | $180,544 | $86.80 |
| 3 | Montefiore Mount Vernon Hospital | $168,015 | $80.78 |
| 4 | Memorial Healthcare System | $161,245 | $77.52 |
| 5 | BronxCare Health System | $160,071 | $76.96 |
| 6 | St Joseph Medical Group | $159,359 | $76.61 |
| 7 | Billings Clinic | $158,932 | $76.41 |
| 8 | Northwell Health | $158,887 | $76.39 |
| 9 | Physician Affiliate Group of New York | $156,637 | $75.31 |
| 10 | Private Practice | $156,552 | $75.27 |
| 11 | The Harris Center for Mental Health and IDD | $145,958 | $70.17 |
| 12 | Moffitt Cancer Center | $145,393 | $69.90 |
| 13 | Yakima Valley Farm Workers Clinic | $145,086 | $69.75 |
| 14 | White Plains Hospital | $143,842 | $69.15 |
| 15 | Mount Sinai Health System | $143,327 | $68.91 |
| 16 | The Arora Group | $142,481 | $68.50 |
| 17 | Health Alliance | $141,149 | $67.86 |
| 18 | Atrium Health Floyd | $139,257 | $66.95 |
| 19 | Froedtert Hospital | $138,867 | $66.76 |
| 20 | Summit Health Oregon | $138,598 | $66.63 |
The average physician assistant, internal medicine salary has risen by $29,127 over the last ten years. In 2014, the average physician assistant, internal medicine earned $96,609 annually, but today, they earn $125,736 a year. That works out to a 14% change in pay for physician assistants, internal medicine over the last decade.
Compare physician assistant, internal medicine salaries for cities or states with the national average over time.
Compare physician assistant, internal medicine salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $126,000 | $60.45 | +2.7% |
| 2024 | $122,000 | $58.81 | +3.3% |
| 2023 | $118,000 | $56.90 | +3.5% |
| 2022 | $114,000 | $54.93 | +3.2% |
| 2021 | $111,000 | $53.16 | +3.3% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| Locumjobsonline | Locum Physician Assistant-Internal Medicine To | Milwaukee, WI | 06/29/2025 | $146,090 |
| Headlandsresearch | Nurse Practitioner or Physician Assistant-Internal Medicine/Clinical Research | Riverside, CA | 06/27/2025 | $135,655 |
| Locumjobsonline | Locum Physician Assistant-Internal Medicine To | Los Angeles, CA | 06/27/2025 | $146,090 |
| Headlands Research | Nurse Practitioner or Physician Assistant-Internal Medicine/Clinical Research | Riverside, CA | 06/26/2025 | $135,655 |
| Locumjobsonline | Locum Physician Assistant-Internal Medicine To | Moses Lake, WA | 06/26/2025 | $146,090 |
| BJC Healthcare | Nurse Practitioner or Physician Assistant Geriatric Internal Medicine at Mhb/Mhs | Belleville, IL | 06/25/2025 | $95,701 |
| Mayo Clinic Health System | Nurse Practitioner or Physician Assistant-Hospital Internal Medicine Nocturnist | Mankato, MN | 06/25/2025 | $128,419 |
| Sutterhealth | Physician Assistant, Aptos Internal Medicine | Aptos, CA | 06/20/2025 | $184,825 |
| Uc Health | Physician Assistant or Nurse Practitioner-Internal Medicine Priority Care | Greeley, CO | 06/17/2025 | $93,891 |
| NSI Healthcare | Nurse Practitioner or Physician Assistant-Internal Medicine | Fayetteville, NC | 06/10/2025 | $100,000 |
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