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As of October 2025, the average salary for a Senior Clinical Research Associate stands at $95,878 annually, equivalent to about $46 per hour. This figure can vary significantly based on factors such as geographical location, years of experience, and the specific healthcare sector.
As clinical research continues to expand, the demand for Senior Clinical Research Associates is expected to rise. This role not only offers competitive pay but also presents numerous pathways for career advancement in clinical management or regulatory affairs.
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The average senior clinical research associate salary in Washington, California, and Hawaii are the highest in the U.S. The lowest average senior clinical research associate salary states are Kentucky, Kansas, and Arkansas.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | California | $106,949 | $51.42 |
| 2 | New Mexico | $93,715 | $45.06 |
| 3 | Massachusetts | $94,789 | $45.57 |
| 4 | Vermont | $94,902 | $45.63 |
| 5 | Pennsylvania | $90,621 | $43.57 |
| 6 | Connecticut | $93,465 | $44.94 |
| 7 | Washington | $109,194 | $52.50 |
| 8 | New Hampshire | $95,388 | $45.86 |
| 9 | New Jersey | $92,331 | $44.39 |
| 10 | Arizona | $89,345 | $42.95 |
| 11 | Rhode Island | $86,436 | $41.56 |
| 12 | Delaware | $91,468 | $43.98 |
| 13 | New York | $92,527 | $44.48 |
| 14 | Michigan | $85,807 | $41.25 |
| 15 | Maine | $84,960 | $40.85 |
| 16 | Oregon | $86,233 | $41.46 |
| 17 | Nevada | $91,134 | $43.81 |
| 18 | Hawaii | $96,136 | $46.22 |
| 19 | Idaho | $87,704 | $42.17 |
| 20 | District of Columbia | $88,135 | $42.37 |
| 21 | North Carolina | $79,579 | $38.26 |
| 22 | Montana | $80,984 | $38.93 |
| 23 | North Dakota | $79,982 | $38.45 |
| 24 | Ohio | $83,392 | $40.09 |
| 25 | Iowa | $84,179 | $40.47 |
| 26 | South Carolina | $85,478 | $41.10 |
| 27 | Maryland | $87,457 | $42.05 |
| 28 | Texas | $78,986 | $37.97 |
| 29 | Minnesota | $77,757 | $37.38 |
| 30 | Illinois | $78,687 | $37.83 |
| 31 | Alaska | $84,478 | $40.61 |
| 32 | Indiana | $77,412 | $37.22 |
| 33 | West Virginia | $75,178 | $36.14 |
| 34 | Florida | $74,115 | $35.63 |
| 35 | South Dakota | $73,080 | $35.13 |
| 36 | Virginia | $77,704 | $37.36 |
| 37 | Utah | $71,487 | $34.37 |
| 38 | Colorado | $71,835 | $34.54 |
| 39 | Wyoming | $73,195 | $35.19 |
| 40 | Louisiana | $71,510 | $34.38 |
| 41 | Georgia | $72,986 | $35.09 |
| 42 | Nebraska | $70,092 | $33.70 |
| 43 | Mississippi | $72,559 | $34.88 |
| 44 | Missouri | $70,138 | $33.72 |
| 45 | Wisconsin | $70,416 | $33.85 |
| 46 | Kansas | $67,009 | $32.22 |
| 47 | Kentucky | $68,429 | $32.90 |
| 48 | Tennessee | $65,236 | $31.36 |
| 49 | Arkansas | $66,119 | $31.79 |
| 50 | Oklahoma | $63,126 | $30.35 |
| 51 | Alabama | $65,050 | $31.27 |
The highest-paying cities for senior clinical research associates are San Francisco, CA, Seattle, WA, and Boston, MA.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | San Francisco, CA | $115,110 | $55.34 |
| 2 | Seattle, WA | $110,460 | $53.11 |
| 3 | Boston, MA | $94,816 | $45.58 |
| 4 | New Haven, CT | $93,573 | $44.99 |
| 5 | New York, NY | $92,642 | $44.54 |
| 6 | Edison, NJ | $92,248 | $44.35 |
| 7 | Wilmington, DE | $91,814 | $44.14 |
| 8 | Philadelphia, PA | $91,271 | $43.88 |
| 9 | Las Vegas, NV | $90,612 | $43.56 |
| 10 | Phoenix, AZ | $89,809 | $43.18 |
| 11 | Washington, DC | $88,244 | $42.42 |
| 12 | Baltimore, MD | $87,845 | $42.23 |
| 13 | Detroit, MI | $86,171 | $41.43 |
| 14 | Portland, OR | $85,911 | $41.30 |
| 15 | Portland, ME | $85,816 | $41.26 |
| 16 | Charleston, SC | $85,122 | $40.92 |
| 17 | Des Moines, IA | $82,766 | $39.79 |
| 18 | Columbus, OH | $82,397 | $39.61 |
| 19 | Raleigh, NC | $81,068 | $38.98 |
| 20 | Austin, TX | $80,368 | $38.64 |
A senior clinical research associate's salary ranges from $64,000 a year at the 10th percentile to $142,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $142,000 | $11,833 | $68 |
| 75th Percentile | $118,000 | $9,833 | $57 |
| Average | $95,878 | $7,990 | $46 |
| 25th Percentile | $77,000 | $6,417 | $37 |
| 10th Percentile | $64,000 | $5,333 | $31 |
The highest paying types of senior clinical research associates are clinical project manager, clinical research manager, and clinical trial manager.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Study Director | $82,066 | $6,839 | $39.45 | 6,789 |
| Study Coordinator | $47,435 | $3,953 | $22.81 | 14,929 |
| Clinical Project Manager | $100,510 | $8,376 | $48.32 | 153,837 |
| Clinical Trial Coordinator | $50,720 | $4,227 | $24.38 | 64,859 |
| Research Project Coordinator | $48,683 | $4,057 | $23.41 | 67,800 |
| Research Nurse | $53,463 | $4,455 | $25.70 | 46,665 |
Top companies hiring senior clinical research associates now:
Senior clinical research associate salaries at Acorda Therapeutics and Zymeworks are the highest-paying according to our most recent salary estimates. In addition, the average senior clinical research associate salary at companies like Emergent BioSolutions and Edwards Lifesciences are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Acorda Therapeutics | $131,660 | $63.30 |
| 2 | Zymeworks | $127,115 | $61.11 |
| 3 | Emergent BioSolutions | $126,066 | $60.61 |
| 4 | Edwards Lifesciences | $119,327 | $57.37 |
| 5 | Allergan plc | $118,636 | $57.04 |
| 6 | ImClone Systems LLC | $113,171 | $54.41 |
| 7 | AbbVie | $111,452 | $53.58 |
| 8 | Merck | $111,192 | $53.46 |
| 9 | Stryker | $107,788 | $51.82 |
| 10 | Moderna | $104,645 | $50.31 |
| 11 | Parexel International | $101,523 | $48.81 |
| 12 | REGENXBIO | $100,861 | $48.49 |
| 13 | Boston Scientific | $100,321 | $48.23 |
| 14 | Pharmaceutical Research Associates, Inc. | $99,818 | $47.99 |
| 15 | BioMarin | $99,041 | $47.62 |
| 16 | Seagen | $98,794 | $47.50 |
| 17 | FibroGen | $96,122 | $46.21 |
| 18 | Randstad North America, Inc. | $93,664 | $45.03 |
| 19 | Astellas Pharma | $93,447 | $44.93 |
| 20 | Teleflex | $92,748 | $44.59 |
The average senior clinical research associate salary has risen by $16,105 over the last ten years. In 2014, the average senior clinical research associate earned $79,774 annually, but today, they earn $95,878 a year. That works out to a 15% change in pay for senior clinical research associates over the last decade.
Compare senior clinical research associate salaries for cities or states with the national average over time.
Compare senior clinical research associate salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $95,900 | $46.10 | +6.4% |
| 2024 | $89,700 | $43.14 | +4.1% |
| 2023 | $86,100 | $41.39 | +3.9% |
| 2022 | $82,700 | $39.76 | -0.7% |
| 2021 | $83,300 | $40.05 | -0.3% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| St. Jude Children's Research Hospital | SR Clinical Research Associate | Memphis, TN | 06/25/2025 | $78,000 |
| Syneos Health, Inc. | SR Clinical Research Associate-Sponsor Dedicated-Oncology (Home-Based In Western US) | Morrisville, NC | 06/10/2025 | $80,600 |
| St. Jude Children's Research Hospital | SR Clinical Research Associate | Memphis, TN | 05/30/2025 | $78,000 |
| Bayside Solutions | Senior CRA/Clinical Research Associate | San Francisco, CA | 05/30/2025 | $89,400 |
| GQR | SR. Clinical Research Associate | San Jose, CA | 05/30/2025 | $177,395 |
| Dexcom | SR Clinical Research Associate | San Diego, CA | 05/27/2025 | $95,900 |
| Quintilesims | Senior Clinical Research Associate, Early Clinical Development | Carlsbad, CA | 05/27/2025 | $87,200 |
| Quintilesims | (Senior) Clinical Research Associate-Sponsor Dedicated | Parsippany-Troy Hills, NJ | 05/27/2025 | $71,900 |
| EPM Scientific | SR. Clinical Research Associate | San Jose, CA | 05/27/2025 | $100,000 |
| Spyglass Pharma | Senior Clinical Research Associate | Aliso Viejo, CA | 05/23/2025 | $90,000 |
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