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A Senior Clinical Scientist plays a crucial role in the healthcare industry, often involved in clinical trials and regulatory submissions. The average salary for this position, as of October 2025, is $124,181 per year or about $60 per hour. Compensation can vary based on factors such as geographic location, years of experience, and the specific industry.
Understanding where senior clinical scientists earn the most can guide job seekers in their career strategies. States like California and Massachusetts typically offer higher salaries due to the concentration of healthcare facilities and research organizations.
Within the healthcare sector, pharmaceutical companies and biotechnology firms often provide the highest salaries for senior clinical scientists. This reflects the demand for expertise in developing innovative medical solutions.
With a variety of roles available, including positions in research management and regulatory affairs, professionals can advance their careers while contributing to impactful healthcare advancements.
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The average senior clinical scientist salary in Alaska, Indiana, and Montana are the highest in the U.S. The lowest average senior clinical scientist salary states are Colorado, Nebraska, and Louisiana.
| Rank | State | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Maine | $137,783 | $66.24 |
| 2 | New Jersey | $137,682 | $66.19 |
| 3 | Montana | $150,538 | $72.37 |
| 4 | Connecticut | $136,511 | $65.63 |
| 5 | California | $143,289 | $68.89 |
| 6 | Indiana | $155,788 | $74.90 |
| 7 | Tennessee | $137,474 | $66.09 |
| 8 | Alaska | $158,727 | $76.31 |
| 9 | Wisconsin | $131,652 | $63.29 |
| 10 | North Carolina | $123,884 | $59.56 |
| 11 | Oregon | $128,306 | $61.69 |
| 12 | Delaware | $128,958 | $62.00 |
| 13 | Maryland | $128,973 | $62.01 |
| 14 | Pennsylvania | $123,036 | $59.15 |
| 15 | Illinois | $126,710 | $60.92 |
| 16 | District of Columbia | $130,121 | $62.56 |
| 17 | Washington | $119,717 | $57.56 |
| 18 | Nevada | $122,157 | $58.73 |
| 19 | Ohio | $121,143 | $58.24 |
| 20 | Minnesota | $122,670 | $58.98 |
| 21 | Hawaii | $124,990 | $60.09 |
| 22 | Wyoming | $117,298 | $56.39 |
| 23 | Rhode Island | $113,319 | $54.48 |
| 24 | Virginia | $119,180 | $57.30 |
| 25 | Massachusetts | $114,016 | $54.82 |
| 26 | Arizona | $117,441 | $56.46 |
| 27 | Vermont | $115,089 | $55.33 |
| 28 | New York | $114,103 | $54.86 |
| 29 | South Dakota | $109,541 | $52.66 |
| 30 | Arkansas | $114,035 | $54.82 |
| 31 | Oklahoma | $113,782 | $54.70 |
| 32 | Iowa | $109,857 | $52.82 |
| 33 | Texas | $105,211 | $50.58 |
| 34 | North Dakota | $98,456 | $47.33 |
| 35 | Michigan | $107,131 | $51.51 |
| 36 | Kansas | $103,678 | $49.85 |
| 37 | Alabama | $107,714 | $51.79 |
| 38 | New Mexico | $102,378 | $49.22 |
| 39 | West Virginia | $100,681 | $48.40 |
| 40 | Florida | $101,572 | $48.83 |
| 41 | Kentucky | $102,863 | $49.45 |
| 42 | New Hampshire | $106,486 | $51.20 |
| 43 | Missouri | $100,621 | $48.38 |
| 44 | Idaho | $101,264 | $48.68 |
| 45 | Colorado | $94,687 | $45.52 |
| 46 | Georgia | $101,370 | $48.74 |
| 47 | Utah | $85,605 | $41.16 |
| 48 | Louisiana | $90,715 | $43.61 |
| 49 | Nebraska | $93,094 | $44.76 |
| 50 | South Carolina | $88,511 | $42.55 |
| 51 | Mississippi | $88,650 | $42.62 |
The highest-paying cities for senior clinical scientists are Indianapolis, IN, San Francisco, CA, and Rahway, NJ.
| Rank | City | Avg. salary | Hourly rate |
|---|---|---|---|
| 1 | Indianapolis, IN | $155,822 | $74.91 |
| 2 | San Francisco, CA | $149,215 | $71.74 |
| 3 | Rahway, NJ | $137,748 | $66.22 |
| 4 | Memphis, TN | $137,695 | $66.20 |
| 5 | Ridgefield, CT | $136,427 | $65.59 |
| 6 | Madison, WI | $131,732 | $63.33 |
| 7 | Baltimore, MD | $129,058 | $62.05 |
| 8 | North Chicago, IL | $126,777 | $60.95 |
| 9 | Durham, NC | $123,990 | $59.61 |
| 10 | Minneapolis, MN | $122,732 | $59.01 |
| 11 | Las Vegas, NV | $121,387 | $58.36 |
| 12 | Seattle, WA | $120,485 | $57.93 |
| 13 | New York, NY | $114,195 | $54.90 |
| 14 | Little Rock, AR | $114,149 | $54.88 |
| 15 | Boston, MA | $114,124 | $54.87 |
| 16 | Des Moines, IA | $109,862 | $52.82 |
| 17 | Birmingham, AL | $107,678 | $51.77 |
| 18 | Detroit, MI | $107,197 | $51.54 |
| 19 | Fort Worth, TX | $105,275 | $50.61 |
| 20 | Wichita, KS | $104,092 | $50.04 |
A senior clinical scientist's salary ranges from $97,000 a year at the 10th percentile to $158,000 at the 90th percentile.

| Percentile | Annual salary | Monthly salary | Hourly rate |
|---|---|---|---|
| 90th Percentile | $158,000 | $13,167 | $76 |
| 75th Percentile | $141,000 | $11,750 | $68 |
| Average | $124,181 | $10,348 | $60 |
| 25th Percentile | $109,000 | $9,083 | $52 |
| 10th Percentile | $97,000 | $8,083 | $47 |
The highest paying types of senior clinical scientists are medical science liaison, principal scientist, and senior scientist.
| Job title | Annual salary | Monthly salary | Hourly rate | Job openings |
|---|---|---|---|---|
| Research Fellow | $53,823 | $4,485 | $25.88 | 59,746 |
| Fellow | $66,364 | $5,530 | $31.91 | 7,459 |
| PHD Researcher | $51,634 | $4,303 | $24.82 | 19,736 |
| Laboratory Researcher | $27,760 | $2,313 | $13.35 | 57,359 |
| Researcher | $67,145 | $5,595 | $32.28 | 30,498 |
| Research Laboratory Manager | $64,333 | $5,361 | $30.93 | 89,981 |
Top companies hiring senior clinical scientists now:
Senior clinical scientist salaries at California Resources and Agenus are the highest-paying according to our most recent salary estimates. In addition, the average senior clinical scientist salary at companies like Hunt Oil and Neurocrine Biosciences are highly competitive.
| Rank | Company | Average salary | Hourly rate |
|---|---|---|---|
| 1 | California Resources | $164,742 | $79.20 |
| 2 | Agenus | $145,401 | $69.90 |
| 3 | Hunt Oil | $142,479 | $68.50 |
| 4 | Neurocrine Biosciences | $141,131 | $67.85 |
| 5 | Genentech | $137,582 | $66.15 |
| 6 | EOG Resources | $136,306 | $65.53 |
| 7 | Lumina Geophysical | $135,293 | $65.04 |
| 8 | Hoffmann-LA Roche Inc | $135,133 | $64.97 |
| 9 | CNOOC Petroleum North America ULC | $134,561 | $64.69 |
| 10 | Seres Therapeutics | $133,248 | $64.06 |
| 11 | Biogen | $133,096 | $63.99 |
| 12 | Regeneron | $132,309 | $63.61 |
| 13 | EyePoint Pharmaceuticals | $131,912 | $63.42 |
| 14 | Planet Pharma | $130,249 | $62.62 |
| 15 | EQRx | $129,531 | $62.27 |
| 16 | BeiGene | $129,358 | $62.19 |
| 17 | Constellation Pharmaceuticals | $129,176 | $62.10 |
| 18 | Medical Science & Computing, LLC | $129,144 | $62.09 |
| 19 | Kallyope | $129,094 | $62.06 |
| 20 | Alexion Pharmaceuticals | $129,087 | $62.06 |
The average senior clinical scientist salary varies across industries:
| Rank | Industry | Average salary | Hourly rate |
|---|---|---|---|
| 1 | Energy | $141,546 | $68.05 |
| 2 | Finance | $130,932 | $62.95 |
| 3 | Pharmaceutical | $124,041 | $59.64 |
| 4 | Health Care | $120,750 | $58.05 |
The average senior clinical scientist salary has risen by $20,871 over the last ten years. In 2014, the average senior clinical scientist earned $103,310 annually, but today, they earn $124,181 a year. That works out to a 14% change in pay for senior clinical scientists over the last decade.
Compare senior clinical scientist salaries for cities or states with the national average over time.
Compare senior clinical scientist salaries for individual cities or states with the national average.
| Year | Avg. salary | Hourly rate | % Change |
|---|---|---|---|
| 2025 | $124,000 | $59.70 | +3.0% |
| 2024 | $120,000 | $57.93 | +4.5% |
| 2023 | $115,000 | $55.33 | +3.2% |
| 2022 | $111,000 | $53.56 | +1.9% |
| 2021 | $109,000 | $52.54 | -2.1% |
| Company | Job | Location | Date added | Salary |
|---|---|---|---|---|
| Fortrea | Senior Clinical Scientist (Pharmacologist)-Pharmacology, US Remote Based | Durham, NC | 06/28/2025 | $110,000 |
| Scientific Search | Clinical Scientist-Manager-SR. Manager | New York, NY | 06/20/2025 | $115,000 |
| Radionetics Oncology | Director/Senior Director, Clinical Scientist | San Diego, CA | 06/14/2025 | $250,000 |
| Xenon Pharmaceuticals Inc. | Scientist 3/Senior Scientist, Clinical Pharmacology | Boston, MA | 06/14/2025 | $135,000 |
| Denali | Senior Scientist, Clinical Pharmacology | South San Francisco, CA | 06/09/2025 | $142,000 |
| Abbott Laboratories | Senior Clinical Scientist | Santa Clara, CA | 05/29/2025 | $98,000 |
| Pfizer | Late Stage Oncology Clinical Scientist-Thoracic (Senior Manager) | New York, NY | 05/28/2025 | $135,100 |
| Pfizer | Late Stage Oncology Clinical Scientist-Thoracic (Senior Manager) | Groton, CT | 05/28/2025 | $135,100 |
| Pfizer | Late Stage Oncology Clinical Scientist-Thoracic (Senior Manager) | York, PA | 05/28/2025 | $135,100 |
| Third Rock Ventures | Senior Scientist I, Clinical Pharmacology and Quantitative Pharmacology | Redwood City, CA | 05/26/2025 | $144,000 |
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