Scholar Rock, Inc. is a biopharmaceutical company focused on the discovery and development of innovative medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. Our newly elucidated understanding of the molecular mechanisms of growth factor activation enabled us to develop a proprietary platform for the discovery and development of monoclonal antibodies that locally and selectively target these signaling proteins at the cellular level. We believe this approach, acting in the disease microenvironment, avoids the historical challenges associated with inhibiting growth factors for therapeutic effect. We believe our focus on biologically validated growth factors may facilitate a more efficient development path. We are advancing our lead product candidate, SRK-015, a selective first-in-class inhibitor of the activation of the growth factor myostatin in skeletal muscle, into clinical development for the treatment of spinal muscular atrophy, or SMA. We expect to initiate a Phase 1 clinical trial in the second quarter of 2018. Utilizing our proprietary platform, we are also creating a pipeline of novel product candidates with the potential to transform the lives of patients suffering from a wide range of serious diseases, including other neuromuscular disorders, cancer, fibrosis and anemia.Based in Cambridge, MA, Scholar Rock is a small health care company with only 119 employees and an annual revenue of $33.2M.
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The founders of Scholar Rock are Nagesh K. Mahanthappa and Timothy Springer.
The key people at Scholar Rock are Nagesh K. Mahanthappa and Timothy Springer.
Key people
Nagesh K. Mahanthappa
Timothy Springer
Scholar Rock rankings
Scholar Rock is ranked #88 on the Best Health Care companies to work for in Massachusetts list. Zippia's Best Places to Work lists provide unbiased, data-based evaluations of companies. Rankings are based on government and proprietary data on salaries, company financial health, and employee diversity.
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Scholar Rock may also be known as or be related to Scholar Rock, Scholar Rock Holding Corp, Scholar Rock Holding Corporation, Scholar Rock Inc, Scholar Rock, Inc. and Scholar Rock, LLC.