Top Scientist Skills

Below we've compiled a list of the most important skills for a Scientist. We ranked the top skills based on the percentage of Scientist resumes they appeared on. For example, 12.8% of Scientist resumes contained Analytical Methods as a skill. Let's find out what skills a Scientist actually needs in order to be successful in the workplace.

The six most common skills found on Scientist resumes in 2020. Read below to see the full list.

1. Analytical Methods

high Demand
Here's how Analytical Methods is used in Scientist jobs:
  • Utilized and implemented analytical methods and biophysical characterization techniques for in-process check to ensure protein purity/identification/functionality and nucleic acid purity/identification.
  • Created protocols and reports for qualification, validation and transfer of bio/analytical methods in accordance with the current regulatory requirements.
  • Developed and validated quantitative bioanalytical methods to determine various drugs and metabolites in biological fluids using HPLC/MS/MS and UPLC/MS/MS methods.
  • Developed and validated 15 analytical methods for projects at different development stages from early phase to marketed and generic products.
  • Developed 15 analytical methods for assay/related substance analysis, aerosol particle size distribution test, and delivered dose uniformity test.
  • Developed analytical methods and wrote Standard Operating Procedures for environmental (soil and water) samples and pharmaceutical bio-equivalence studies.
  • Optimize analytical methods to reduce the time for analysis and evaluate cost-reduction initiatives to gain efficiency in the Laboratory.
  • Lead Scientist for development, optimization and validation of Analytical methods to qualify new technology HPLC/GC qualification.
  • Developed and validated various bioanalytical methods for the analysis of drug candidates in biological samples using LC-MS/MS.
  • Worked on process improvements projects, including the development of analytical methods to qualify new biological/organic materials.
  • Validated analytical methods pertaining to analysis of raw materials, in-process materials, and finished products.
  • Worked with Quality Control and other Operations groups to trouble-shoot and improve existing analytical methods.
  • Developed, validated and performed bioanalytical methods in support of various 3rd generation research efforts.
  • Developed quality analytical methods with regard to transfer department to reduce overhead and increase throughput.
  • Authored protocols and final reports to facilitate validation of analytical methods and stability studies.
  • Developed platform analytical methods which lead to significant financial savings and optimized resource utilization.
  • Completed forced degradation studies to determine specificity and establish analytical methods as stability indicating.
  • Write Reports, Analytical methods and Protocols for Method development and Method Validations experiments.
  • Developed, validated and transferred analytical methods for a variety of projects in development.
  • Trained new analysts/ users on analytical methods, standard operating procedures and instrument use/care.

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2. Lab Equipment

high Demand
Here's how Lab Equipment is used in Scientist jobs:
  • Established and managed preventative maintenance and calibration schedules for lab equipment.
  • Train coworkers on new lab equipment/Technology operation and maintenance.
  • Maintained operation of lab equipment and performed troubleshooting.
  • Managed productivity and efficiency of the lab equipment.
  • Maintained and troubleshooted lab equipment.
  • Added one report (technician) and trained individual with lab equipment and technical writing for development of novel cellulose-based technology.
  • Evaluated and recommended laboratory equipment purchase and technical protocols, performed IQ/ OQ/ PQ of new lab equipment including troubleshooting.
  • Acquire new lab equipment through existing J&J companies to enable required testing while remaining under budget.
  • Prepare lab reagents, participate in maintaining lab equipment and samples, and support lab safety.
  • Train new hires and current team members on safe operation of mechanical testing lab equipment.
  • Completed troubleshooting of malfunctioning lab equipment to complete all assignments on time with high quality.
  • Installed lab equipment for new IDEM lab's new air monitoring branch.
  • Carried out regular monitoring, calibration, resolve troubleshooting of lab equipment.
  • Maintain lab equipment and follow lab quality and safety requirements.
  • Purchased stock supplies for lab and maintained lab equipment.
  • Perform preventive maintenance on lab equipment.
  • Calibrate and maintain all lab equipment.
  • Maintain minor adjustments to lab equipment.
  • Evaluated and recommended capital appropriations for new lab equipment to expand analytical capabilities for the lab in support of critical projects.
  • Monitor and troubleshoot analytical devices including calibration, and quality control, along with recording normal operations of lab equipment.

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3. Cell Culture

high Demand
Here's how Cell Culture is used in Scientist jobs:
  • Mentored junior scientists in cell culture technology and cellular biology and provided support in troubleshooting, and atypical issue resolution.
  • Provided training and support for Manufacturing Technologies group members and GMP Manufacturing Associates for cell culture and purification techniques.
  • Managed cell culture facility in supervisor s absence and conducted personnel conferences/meetings, ensuring seamless operations over 4-month period.
  • Supervised and trained laboratory technicians on surgical procedures, cell culture methods, and evaluation of histology samples.
  • Developed a variety of research methodologies utilizing immunology, molecular biology and cell culture techniques.
  • Developed and executed alternative cell culture medium to improve large-scale vector production.
  • Process development and optimization for large-scale cell culture using cell factories.
  • Developed harvest, clarification and filtration procedures after cell culture.
  • Maintained cell cultures and performed cell culture-based assays.
  • Performed mammalian cell culture and assay development.
  • Completed a K2 cell culture project to confirm the K2 cell subclass and to evaluate the cell subclass switch in culture.
  • Worked on different Primary Cell Cultures including Mouse & Rat (Dorsal Root Ganglion) Neurons with dosing of animals.
  • Maintain all cell cultures for feline virology laboratory such as CRFK's, SF9's, and HEK 293's.
  • Lead multiple cell line drug treatment activities across various projects and served as subject master expert for cell culture activities.
  • Conducted cell culture, molecular biology and FACS Analysis techniques for successful progression of various stem cell related projects.
  • Formulated Cell Plating Reagents and Cell Culture Reagents using aseptic techniques and sterile conditions followed by GMP and GLP.
  • Set up and started the new wet lab and cell culture system, as well as manage the lab.
  • Evaluated and applied novel technology and methods (high density cell culture and cell separation) to streamline processes.
  • Set up and established embryonic stem cell culture, genetic modification, micro-injection, and production of chimeric mice.
  • Provided technical support by developing new methods for Raw Materials, Cell Culture Media and for new formulations.

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4. New Product Development

high Demand
Here's how New Product Development is used in Scientist jobs:
  • Worked cross-functionally with production and marketing departments, assisted transition from the final stage in new product development to manufacturing.
  • Designed and ran experiments to gather data and generate conclusions for continuous improvement and new product development initiatives.
  • Executed new product development and product support activities according to existing protocols or developed or adapted new protocols.
  • Introduced phase-by-phase execution of new product development and measurable parameters for each phase.
  • Analyze cosmetic and personal care products for preservatives, sunscreens, and other actives supporting stability studies and new product development.
  • Led technical aspects of new product development and product improvement projects for blood coagulation tests and assays.
  • Keep the Laboratory Manager informed of the progress of testing activities and new product development projects.
  • Collaborated with business and toxicology team members on new product development in Stage Gate process.
  • Led new product development based on customer needs and market value.
  • Core Team member representing R&D in new product development.
  • Team player on lateral flow devices new product development team.
  • Assist in validation of new procedures and new product development.
  • Interpreted consumer insights to drive new product development.
  • Support new product development with advanced methods development and validations, generation of technical data in support of clinical API regulatory requirements
  • Provide support to the Formulation and Development department with Excipient compatibility studies for new product development.
  • Performed in-use, simulated-use and bacteriostasis testing in support of new product development for 510(k) submissions.
  • Research & Development - New Product Development Plan, implement, and manage OTC consumer health product formulation strategies.
  • Provided analytical support to formulation and new product development for Metered Dose Inhaler products: Atrovent, Combivent.

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5. Stability Samples

high Demand
Here's how Stability Samples is used in Scientist jobs:
  • Support product formulation department by providing assay, impurity and dissolution profile for initial and stability samples.
  • Performed chemical and physical testing of raw- materials, stability samples and ophthalmology products.
  • Designed stability studies, authored stability protocol, and analyzed stability samples.
  • Employed method for analysis of formulation development samples and stability samples.
  • Perform analysis on stability samples using Dissolution apparatus and HPLC.
  • Performed impurity identification of stability samples for 3 projects.
  • Analyzed stability samples and documented/recorded collected data.
  • Performed accelerated stability testing for stability samples.
  • Maintained inventory of stability samples.
  • Performed routine analysis of in- process, finished products, development batches and stability samples as per in-house monographs.
  • Performed testing of raw materials, in process, finished product and stability samples using in-house and USP/NF method.
  • Performed higher level testing on finished product and stability samples, which included AA, HPLC and GC.
  • Produce reports that allow release, rejection, or retesting on release and/or stability samples to Quality Assurance.
  • Performed the analysis of raw materials, finished product and stability samples using USP Pharmacopoeia methods.
  • Perform complete testing on Clinical samples, stability samples, finished products and commercial release samples.
  • Protected the integrity of valuable stability samples by providing 24hours/7days a week response to chamber excursions.
  • Provided analysis of bulk, intermediate, finished and stability samples of oral solid dosage forms.
  • Analyzed raw materials, finished products and stability samples for compliance with specifications and standards.
  • Performed testing of initial release, in process, finished products and stability samples.
  • Performed routine tests on in-process samples, finished products, commercial and stability samples.

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6. Hplc

high Demand
Here's how Hplc is used in Scientist jobs:
  • Synthesized targeted, enzyme-activated anticancer agents, analyzed and purified compounds by HPLC, and performed prostate specific antigen-catalyzed substrate kinetics.
  • Performed chemical analysis, structure characterizations, HPLC methods development, qualitative and quantitative analysis, and purity and stability determination.
  • Performed dissolution, assay, content uniformity and degradation analyses to ensure compliance with specifications utilizing HPLC.
  • Performed calibration of Waters HPLC and Preventive Maintenance and troubleshooting of other laboratory instruments as well.
  • Devised and conducted stability testing experiments for dosing solutions using Waters HPLC.
  • Developed Related Compounds Method for Hormonal Combination Products using HPLC.
  • Performed HPLC daily, analyzed results and maintained laboratory notebooks.
  • Performed HPLC method development, method validation/transfer of pharmaceutical methods.
  • Maintained/repaired HPLC on regular basis to achieve optimum performance.
  • Developed and implemented procedures to qualify HPLC performance.
  • Performed stability studies on pharmaceuticals using HPLC.
  • Evaluated suitability of published HPLC methodology.
  • Designed and implemented study protocols, developed HPLC methods in various matrices for the measurement of drug and metabolite concentrations.
  • Developed HPLC methods for purification of R&D and stock compounds and performed maintenance and troubleshooting of HPLC instruments.
  • Conduct characterization and impurity identification on raw material for various early and late stage program by HPLC and LC-MS.
  • Performed HPLC method development, validation, assays and analyses in support of product development and NDA filings.
  • Purified and characterized the impurity of DS using HPLC, LC-MS, and various biological and biophysical methods.
  • Optimized an SEC HPLC method at low pH to measure protein aggregation in drug substance and drug product.
  • Design, validate, and optimize an HPLC method that will determine three active ingredients in a capsule.
  • Calibrated And troubleshot Laboratory instruments including Dissolution Apparatus, HPLC, PH Meter, And All Balance.

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7. Protein

high Demand
Here's how Protein is used in Scientist jobs:
  • Manufactured regulated products associated with antibodies- Formulated purified antibodies, formulated conjugated antibodies and performed antibody/protein conjugation.
  • Designed mouse/human protein chimeras to map protein-protein interaction sites; developed constructs based on these designs for use in crystallization studies.
  • Designed and executed cell-based experiments critical to identifying GPR39, an orphan g-protein coupled receptor with links to Hedgehog signaling pathway.
  • Developed assays to determine amount of adhered protein on medical devices; performed quantitative adherence assays using radio-labeled proteins.
  • Published research that helped explained protein-protein interactions leading to crystallization, particle formation, and liquid-liquid phase separation.
  • Provide expert consultation to NCI-Investigators in cell-based assays, imaging, protein identification and validation of protein interactions.
  • Implemented extraction and clarification methods to obtain secreted and cellular antibody and/or antigen proteins for purification.
  • Established a fluorescence-based protein retention assay for guiding membrane development and possible transfer to quality control.
  • Apply fundamental protein chemistry principles in identifying and resolving issues related to protein formulation and development.
  • Put together and led multidisciplinary collaborations and teams to create protein structure-function projects and secure funding.
  • Produced high-quality heat shock proteins by multiple established purification processes for research purposes and animal studies.
  • Conducted metabolic engineering, gene expression, protein purification, and enzyme activity assay.
  • Developed and optimized conditions for chemical conjugation, purification and analysis of PEG-protein conjugates.
  • Trouble shot protein purification method and improved specificity and accuracy of diagnostic test.
  • Designed and performed experiments to study enzyme kinetics, protein unfolding and aggregation.
  • Established and scaled-up protein expression, purification and biochemistry capabilities of the lab.
  • Enriched and characterized the structural variants of monoclonal antibodies and fusion proteins.
  • Developed Formulations using PulmoSphereTM Technology for Antibiotics, Steroids and Proteins.
  • Completed affinity purification of tagged proteins expressed in cells in culture.
  • Helped analyze and solve membrane fouling and protein purification development problems.

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8. Ms

high Demand
Here's how Ms is used in Scientist jobs:
  • Led the Risk-based approach development and implementation of programs toward the qualification and certification of packaging process equipment and computer systems.
  • Developed stress tests and failure mode analysis for optical subsystems and mounted optical assemblies and components thereby formulating effective technical specifications.
  • Collaborated with packaging engineers and process engineers in selection of appropriate materials for container closure systems and manufacturing process contact materials.
  • Conducted troubleshooting analysis during production crisis; efficiently handled and solved impromptu problems that enabled rapid return to normal manufacturing schedule.
  • Developed system to standardize technical training requirements based upon job positions - Conducted basic research to contrast hierarchical job analysis paradigms
  • Developed and field-tested magnetometer signal processing algorithms for a rapidly fielded suites of counter-IED protection measures for mounted ground forces.
  • Developed image and signal processing algorithms for sonar systems, including basic geometric and physical optics and automatic target recognition.
  • Served as a member of several cross functional teams which developed and implemented strategies for product development and identification.
  • Lead new dairy prototype development, culinary applications and process development experiments for dairy systems from bench to commercialization.
  • Facilitated effective team meetings by providing agenda, communicated decisions and delegated action items to team members.
  • Worked collaboratively with cross-functional project teams including engineers, process development, surgical and product testing groups.
  • Served as scientist supporting the Aerosol Sciences and Technology Team investigating chemical and biological defense mechanisms.
  • Supported development and commercialization of proprietary preservative systems for use in cultured products and processed meats.
  • Used finite element analysis to investigate fundamental mechanisms governing device performance and identify critical manufacturing parameters.
  • Selected as lead for high-profile programs, resulting in increased recognition and visibility for company.
  • Act as company representative and presenter at select national professional organization symposiums and conferences.
  • Developed Dissolution methods for immediate release and modified release of oral solid dosage forms.
  • Experienced in using robotic laboratory systems and in using automated laboratory data acquisition systems.
  • Deployed 3 global quality systems compliant with customer expectations, Aerospace and Regulatory standards.
  • Conducted research to troubleshoot problems identified in formulation development and clinical supplies manufacture.

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9. Data Analysis

high Demand
Here's how Data Analysis is used in Scientist jobs:
  • Responded to customer inquiries for data analysis and offered guidance for better usage of biochemical/ kits products to improve customer satisfaction.
  • Facilitated data analysis by generating a protocol for the automation and the capture of high quality images using MetaMorph software.
  • Performed signal processing and field sensor data analysis of Airborne Laser atmospheric compensation, tracking and high energy laser systems.
  • Provide routine sample analysis for oncology research project including assay execution, data analysis and method optimization including automation.
  • Participated in experiment design and performed data analysis for reagent antibody screening projects using indirect ELISA and competitive ELISA.
  • Mentor junior epidemiologists and students; Perform accurate data analysis, write manuscripts, and conduct conference presentations.
  • Interacted with statisticians to establish data analysis templates that substantially increased efficiency and accuracy of study data analysis.
  • Designed, developed and provided training for customized computerized tracking, monitoring, budgeting and data analysis schemes.
  • Developed the methods of data analysis in mechanical engineering in application to express diagnostics of friction junctions.
  • Managed multiple research studies in parallel from study initiation and execution to data analysis and report generation.
  • Executed genetic data output, subsequent data analysis and processing, and complex quality assessment reports.
  • Delivered on pharmacological data analysis, including statistical and nonlinear regression modeling, to drive decision-making.
  • Managed multiple cell based assays and performed data analysis and data reporting of several disease targets.
  • Instituted data analysis and interpretation parameters to assess gene expression in animal tissues from disease models.
  • Perform data analysis of calibration curve and quality controls make decisions on reporting data to physician.
  • Documented laboratory data in compliance with guidelines; presented data analysis summaries at laboratory meetings.
  • Prepared reports/papers on experimental testing and data analysis in cross-functional teams to achieve company strategies.
  • Conduct market analysis to determine key opportunities and challenges facing development of data analysis.
  • Provided quality data analysis acquired from proven processes for accurate and valuable study conclusions.
  • Assisted with data analysis, writing protocols and reports for various investigations and validations.

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10. R

high Demand
Here's how R is used in Scientist jobs:
  • Managed, performed, documented, and reviewed operational equipment protocols including IQ/OQ/PQ, preventative maintenance, calibration, and validation.
  • Conducted microbiological techniques including Minimum Inhibitory Concentration and Minimum Bactericidal Concentration assays, combination studies in static concentrations and checkerboard assays.
  • Conduct secondary loop activities for the continuous improvement of existing processes and the development and validation of alternative Insulin manufacturing processes.
  • Collaborated with Soil Fertility Division on correct data utilization, providing agronomic counseling and education to 4-person non-agricultural background team.
  • Performed quality control and stability testing of raw materials, components and finished kits according to House Specifications.
  • Designed an experiment to automatically manipulate experimental devices for optical characterization, saving hundreds of man hours.
  • Designed in-use studies with handmade prototypes for conceptual evaluation and new material screening for several exploratory projects.
  • Perform scientific literature and patent search to remain current with recent developments in generic pharmaceutical research.
  • Utilized process and quality software, supported product safety and conducted material aging stability studies.
  • Invented, prepared and filed two patent applications for novel protein labeling/modification techniques and strategies.
  • Produced high-quality data; Analyzed and summarized data professionally and presented regularly in team meeting.
  • Investigated Mountain Meteorology with a pinpointed focus on project proposals and field campaign implication.
  • Planned and performed laboratory experiments to develop and optimize formulations and manufacturing processes.
  • Managed customer interactions and information to ensure continuous and effective business relationships.
  • Weather resistant and Electrical insulation tapes for ducts and electrical cable applications.
  • Conducted micro flow imaging and HIAC based sub-visible particulate testing and analysis.
  • Developed tool to accurately track material consumption and to verify specification recipe.
  • Support manufacturing operations through sample analysis of both physical and chemical properties.
  • Solved media precipitation issues by conducting media stability and incubation studies.
  • Initiated and monitored stability studies designed to support formulation process changes.

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11. FDA

high Demand
Here's how FDA is used in Scientist jobs:
  • Participated in regulatory meetings and activities including dossier development, drug submissions, and FDA correspondence.
  • Drafted product standards and participated in CFDA regulatory submissions for safety determination and clinical study clearance.
  • Planned, generated, and implemented verification protocols in accordance with FDA guidelines for specific analysis.
  • Ensured that all laboratory experiments and documentation met FDA and other governmental agency requirements.
  • Designed experimentation to provide additional data to support validations in response to FDA questions.
  • Determined contractors' suitability for manufacturing and meeting quality requirements and US FDA compliance.
  • Design and supervise FDA-sponsored research on botanical extracts with associated adverse event reports.
  • Performed gap analysis between validation & verification protocols, instruments and FDA requirements.
  • Participated in successful audit by FDA and external auditors providing requested data.
  • Presented and defended assay validation information to FDA reviewers in Washington.
  • Follow the FDA guidelines and other international regulatory requirement.
  • Assay validation and performance documentation to support FDA submissions.
  • Experience with FDA-regulated manufacturing operations, including QC testing.
  • Participated in authoring draft documentation for FDA submission.
  • Participate in drug development research project following FDA regulation
  • Experience in project management; data collection, management, and analysis; and medical device design in accordance with FDA.
  • Perform validation data collection for FDA 510(k) submission according to Clinical Laboratory Standards Institutes (CLSI) guidelines.
  • Work in conjunction with other internal and cross-functional departments to ensure adherence to FDA or CAP or CLIA standards of compliance.
  • Participate in compliance activities, such as internal audits, FDA and Notified Body audits, complaint handling and vendor audits.
  • Assist internal and external regulatory agencies audit process: FDA, ISO, Corporate groups, third parties and external customers.

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12. Elisa

high Demand
Here's how Elisa is used in Scientist jobs:
  • Experienced scientist in standardizing ELISA assays for existing and synthetic molecules in cancer therapy for Personalized Drug Management.
  • Utilized Elisa, fluorescence polarization assay to identify the target.
  • Developed and validated ELISA method for monoclonal antibody development.
  • Performed antibody screening using regular and competitive binding ELISA.
  • Tested human plasma samples for HIV antibody, Hepatitis C antibody, and Hepatitis B antigen using high throughput ELISA tests.
  • Developed and screened cell based functional assays for follow up of primary screening results using Western Blot and ELISA techniques.
  • Conducted high throughput screening of monoclonal antibody producing cells (ELISA, cell-based assays, HTRF, and FRET).
  • Determined protein expression in cells and tissues via ELISA, Westerns, or multiplex systems, establishing readouts of efficacy.
  • Analyzed proteins and antibodies qualitatively and quantitatively by cell based assays, western blot, SDS- PAGE and binding ELISA
  • Lead a department team in an effort to deploy experimentally proven antibody pairs to clinically relevant ELISA based assays.
  • Conducted field work: collection of dust samples, and lab work: extraction of dust samples and ELISA.
  • Project Lead Scientist in the development and validation of ELISA assays for use in toxicology and clinical testing.
  • Designed and developed sensors for lateral flow, SNAP and ELISA test formats for product launch in 2015-2016.
  • Prepared buffers up to 200 liters to support antibody formulations and other manufacturing groups such as, ELISA.
  • Developed ELISA assays to study the affinities of Fab and the full-length antibodies to the target proteins.
  • Created various assays (PCR, FACS, & ELISA based) to test novel reporter gene/probes.
  • Supported cell line development and formulation of the lead antibody with potency assay via a competitive ELISA.
  • Developed, validated, and performed ELISA assays of toxic substances in compliance with CDC regulations.
  • Determined prevalence of dengue infection and dengue virus strain by collecting blood samples and performing ELISA.
  • Authored standard operating procedures for assays in FRET, ELISA, luminescence, and fluorescence platforms.

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13. DNA

high Demand
Here's how DNA is used in Scientist jobs:
  • Supervised, scheduled and executed laboratory experiments to evaluate the performance of developmental and competitor's DNA sequencing reaction purification systems.
  • Project 1: Determined patient-specific somatic DNA structural variation with massively parallel sequencing in prostate and pancreatic solid tumors.
  • Assay Development -develop and perform screening methods for detection and quantification of cellular components including proteins and DNA.
  • Design and execute assay testing to provide engineering design specifications for an integrated DNA analysis system.
  • Utilized DNA-based immunization (BioRad Helios) to effectively generate highly-specific antibodies towards membrane-bound receptors.
  • Performed surface DNA melting measurements to reveal fundamental aspects of DNA hybridization at interfaces.
  • Synthesized a novel base analog for incorporation into DNA sequences for model hybridization studies.
  • Evaluated and improved experimental equipment for card-based two-zone DNA amplification platforms.
  • Managed Transgenic/Knock-out Mouse facility, performed PCR analysis of mouse DNA
  • Established a computerized DNA fingerprinting system for crop variety identification.
  • Used technologies include DNA cloning and automatic based-sequencing instrumentation
  • Developed proprietary enhanced sensitivity DNA amplification method.
  • Managed daily operation of DNA sequencing laboratories.
  • Developed theory of DNA-microchip background elimination method.
  • Investigated and developed formulations of Ion Spheres Particles for PGM used in manufacturing to create next generation DNA sequencing consumer product.
  • Co-developed HLA tissue cross matching assay for organ and bone marrow transplantation based on DNA sequencing and employing capillary DNA sequencer.
  • Performed DNA extraction, PCR amplification and sequencing of samples, collected, documented and photographed various crime scene evidences.
  • Conducted mutation screening and detection of asthma candidate genes, e.g., EDNRB, using SSCP and manual DNA sequencing.
  • Prepared and conducted lab experiments to create DNA products to analyze whether a patient was compatible with an organ transplant.
  • Researched to improve DNA vaccines through novel, targeted delivery systems as part of a joint Georgia Tech / CDC project

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14. GLP

high Demand
Here's how GLP is used in Scientist jobs:
  • Managed laboratory operations in Life Sciences department including acquisition, calibration, and maintenance of equipment that produced GLP compliance.
  • Purified antibodies and antigens for antibody affinity screens, biochemical and cell-based assays, immunizations, and GLP toxicology studies.
  • Designed experiments, prepared protocols and reports to support non-GLP toxicology studies and provided interpretation of clinical pathology data.
  • Coordinated integration of training documentation for four discovery and development research functions into a single electronic GLP compliant system.
  • Developed and implemented GLP standards and validation studies with Quality Control personnel.
  • Maintain proper documentation of assay development-related work in a GLP/QSR-compliant manner.
  • Conduct numerous developmental and reproductive toxicology studies in GLP environment.
  • Facilitated vendor orders, GLP compliance and supported experimentation applications.
  • Served as internal laboratory auditor for GLP regulations.
  • Perform dose confirmation analysis for GLP toxicology formulations.
  • Reviewed GLP toxicology and safety study protocol.
  • Conducted several assays under GLP requirements.
  • Perform all procedures following GLP/GCP guidelines
  • Develop and maintain a Risk Assessment Plan for R&D laboratory instruments and equipment used for GMP and GLP analysis.
  • Served as study director which included: writing protocols, developing methods, conducting GLP studies, and writing final reports.
  • Prepared experimental compounds for the live studies through formulation, strict adherence to SOP's, GLP's and GMP's
  • Perform work in accordance with company policies and regulatory requirements, including but not limited to SOP and GLP.
  • Generate data according to Protocols, SOP's, Non-GLP and GLP compliance with the appropriate regulatory agencies.
  • Worked in GLP environment and routinely served as study lead or study assistant and trained several staff members.
  • Prepared protein conjugates for research/GLP testing in FACS, histology (i.e., toxin-antibody, label- protein).

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15. Raw Materials

average Demand
Here's how Raw Materials is used in Scientist jobs:
  • Developed KF procedure to improve efficiency and accuracy of the current procedure for water determination in Raw Materials and Finished Product.
  • Evaluated replacement of rare disease raw materials with chimeric /humanized antibodies by feasibility/validation studies and qualified new vendors.
  • Generated technical justifications for all identified Raw materials to be qualified for Reduced testing using SPC.
  • Supported in-process and release testing of raw materials and impurities to support manufacturing and method development.
  • Assist in the establishment quality specifications for incoming raw materials, in-process components and finished products.
  • Collected and analyzed data and determined correlation between properties of raw materials/ products and performance.
  • Provided for the analysis of raw materials and in-process material formulations to support lens manufacturing.
  • Developed and validated microbial test methods used for evaluating all products and raw materials.
  • Perform physical testing and microbiological assays on finished products and raw materials.
  • Established vendor qualification processes for all incoming raw materials and reagents.
  • Tested various chemical raw materials for conformity to certificates of analyses.
  • Participated in Raw Materials Testing transfer methods.
  • Managed the internal raw material portfolio and complexity reduction to decrease the number of raw materials, specifications, and suppliers.
  • Write and review SOP, protocols, specifications for various equipment, studies, and raw materials/ finished products respectively.
  • Discover new technologies, new formula bases, raw materials and processing techniques that provide unique product claims and benefits.
  • Managed and oversaw laboratory testing services including raw materials, in process and final product sampling and testing of produce.
  • Analyzed raw materials, in process, and finished products following USP and international pharmacopoeias and company SOP's.
  • Developed sampling programs and conducted analysis to maintain quality standards of raw materials, chemical intermediates, and products.
  • Performed functional and chemical testing of raw materials, intermediates, bulks, finished components and packed kits.
  • Assisted in the development of in-house methods for general laboratory use in testing raw materials and finished products.

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16. Uv/Vis

average Demand
Here's how Uv/Vis is used in Scientist jobs:
  • Conducted HPLC, dissolution, Karl Fischer, UV/VIS and FTIR analysis to support developmental and commercial compounds.
  • Preformed routine HPLC, UV/VIS, DSC, KF water content, and freeze drying microscope experiments.
  • Perform required testing procedures by utilizing laboratory equipment like Bio-Disc Apparatus, HPLC, and UV/VIS.
  • Performed analytical testing for the stability and formulation groups using HPLC, GC, ICP, KF, FTIR and UV/VIS.
  • Used HPLC, UV/Vis, NMR, and KF for in-process controls when executing a production batch.
  • Performed enzyme kinetics study with HPLC, UV/VIS, and fluorescence spectrometry.
  • Performed Method Validation and Method Verification by HPLC, UPLC, GC, UV/Vis and Malvern Particle Size Analyzer.
  • Calibrate and troubleshoots laboratory instruments such as HPLC, UPLC, UV/VIS Spectrophotometer, TPW and Ion chromatography.
  • Separate and analyze actives and vitamins in over-the-counter dietary supplementproducts using HPLC, UV/Vis, and GC.
  • Developed dissolution and analytical methodologies including HPLC, GC, FTIR, Fluorescence and UV/Vis spectroscopy.
  • Experienced user of HPLC (Waters Data Acquisition System), UV/VIS Spectrophotometer, Fluorescence Spectrophotometer.
  • Utilized GC, UV/vis, FT-IR, pH meter, and titration; used MSDS on a regular basis.
  • Experienced with several instrumentation specialties: UV/Vis Spectrometry Atomic Emission Detection Microwave Extraction

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17. GMP

average Demand
Here's how GMP is used in Scientist jobs:
  • Maintained laboratory documentation, instrument logbooks and notebooks in compliance with company initiatives and GMP standards.
  • Develop procedures and performed feasibility testing/analysis to transfer USP/client developed procedures to internal GMP labs.
  • Performed root cause investigations to resolve deviations and for continuous improvement in GMP manufacturing processes
  • Worked in accordance with current GMP and demonstrated proper laboratory safety and housekeeping practices.
  • Managed and performed product release and stability operations in GMP laboratory.
  • Supervised laboratory and pilot plant technicians in a GMP environment.
  • Developed vaccine production and purification processes towards GMP compliance.
  • Calibrated and maintained GMP critical laboratory equipment.
  • Documented procedures according to GMP regulations.
  • Optimized document retrieval times during regulatory audits by organizing the storage and arrangement of key documents for department's GMP records.
  • Calibrate, maintain laboratory equipment, and participate in troubleshooting, investigation and problem solving to ensure compliance with GMP.
  • Designed, developed, and deployed aerosol test system (ATS-707) in both R&D and GMP settings.
  • Clean, maintain and calibrate laboratory equipment to ensure compliance with current Good Manufacturing Procedures (c GMP).
  • Performed inspections and audits of research laboratory and production sites to ensure safety and GMP compliance of the facilities.
  • Review work of other chemists to ensure accuracy, completeness and compliance with GMP and departmental SOP.
  • Experience in sample testing, reviewing and approving data for product release under GMP and regulatory compliance.
  • Transfer, training, and implementation of the analysis of a trace impurity at a GMP CMO.
  • Reviewed and verified Good Manufacturing Practice (GMP) laboratory notebook experiments as well as non-GMP.
  • Supported the weekly laboratory clean up and audits to ensure compliance with both GMP and safety.
  • Performed technology integration, method transfer across groups and sites, and GMP data review.

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18. Synthesis

average Demand
Here's how Synthesis is used in Scientist jobs:
  • Experience: Responsibilities included the design, synthesis, purification and characterization of small molecules for two internal drug discovery programs.
  • Analyzed parallel synthesis libraries using high-throughput LC/MS methods with UV/ELS detection including mass determination, purity evaluation, and quantification.
  • Contributed synthetic and medicinal chemistry expertise to drug discovery research projects * Designed and executed synthesis of biologically active compounds.
  • Conducted independent research studies in organic chemistry, primarily related to synthesis of intermediates and test compounds for biological assays.
  • Performed process development experiments of medicinal chemistry synthesis routes, allowing for scale-up and technical transfer of vital intermediates.
  • Prepared presentations regarding SAR and synthesis of lead compounds and wrote experimental procedures and synthetic schemes for patent publications.
  • Work involved generation of new lead compounds followed by analog synthesis to optimize biological activity using classical SAR analyses.
  • Developed new methodology and optimized new reactions for solution-phase synthesis resulting in more concise synthesis of final compounds.
  • Lead Chemist for the development and optimization of small molecule inhibitors for nicotine cessation o Small molecule synthesis.
  • Developed an efficient synthesis of a key intermediate that was utilized extensively by the team for analog synthesis.
  • Provided technical support for collaborators and prepared associated documents for customer synthesis, outsourced formulation and package projects.
  • Performed synthesis of new components for contact lens formulations using reversible addition fragmentation chain transfer radical polymerization.
  • Design, synthesis and characterization of novel molecular inorganic/organic compounds for use in thin film coatings.
  • Designed, synthesized and characterized compound libraries via parallel synthesis to address issues quickly and efficiently.
  • Worked closely with chemists and engineers to develop proprietary organic synthesis using chemicals from coal technology.
  • Supervised group of chemists from CRO's performing inhibitor synthesis and collaboratively worked with multidisciplinary teams.
  • Bulk synthesis of monomers and polymers using ROMP and further modification by cross-linking for orthopedic applications.
  • Developed factory scale one-step, one kettle semi-synthesis method of human insulin from porcine insulin.
  • Spearheaded effort of incorporating microwave chemistry for library synthesis to expand chemical space for SAR.
  • Maintained the troubleshooting, preventative maintenance, and calibration activities of synthesis lab equipment.

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19. Rt-Pcr

average Demand
Here's how Rt-Pcr is used in Scientist jobs:
  • Noted for effective process improvements, with a particular focus on increasing sensitivity of RT-PCR methods.
  • Extracted RNA from human blood and tissues and performed RT-PCR.
  • Performed nucleic acid extraction, purification and RT-PCR.
  • Designed of RT-PCR diagnostic tests.
  • Performed RT-PCR to evaluate changes in gene expression in response to in vivo compound exposure.
  • Established a high throughput RT-PCR gene expression screening program for identifying target genes.
  • Developed the single cell quantitive RT-PCR gene profiling in functional characterized primary cells.
  • Determined Sipa1L1 mRNA expression in cancerous cell lines by RT-PCR.
  • Determine genes expression level with qRT-PCR.
  • Subject Matter Expert for LifeCell R&D qRT-PCR.
  • Generated genome edited knock out cell lines along with confirming loss of expression in those edited lines using qRT-PCR Taqman analysis.
  • Work with team to perform laboratory support tasks for sample processing for ELISA, rRT-PCR andPRNT testing.
  • Assessed chemokine receptor expression levels in human cancer and primary cell lines using qRT-PCR and copy number.
  • Utilized transposon mutagenesis and qRT-PCR to identify resistance mechanisms of compounds in development.
  • Developed and performed ELISAs, RT-PCR analysis, immunostaining and electrophoresis.
  • Employed RT-PCR and Genescan analysis to identify globally transcribed genes in S. pneumoniae and S. aureus models of infection.
  • Developed a multi-plex biomarker aptamer assay using RT-PCR as a detection platform for Lung and Pancreatic Cancer.
  • Implemented gene expression studies using microarray, RT-PCR, immunofluorescence, and in situ hybridization.

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20. Validation Protocols

average Demand
Here's how Validation Protocols is used in Scientist jobs:
  • Drafted stability indication assay method validation protocols, executed protocols and wrote reports for regulatory submissions.
  • Performed quality control inspections of critical reagents and developed quality control validation protocols of critical reagents.
  • Designed test method characterization and validation protocols, executed the protocols, and developed summary reports.
  • Authored several production records, validation protocols, and reports and other regulatory submissions.
  • Drafted study plans/reports for feasibility experiments as well as stability/verification/validation protocols for each reagent.
  • Developed, audited, and reviewed validation protocols and documentation for processes and equipment.
  • Designed, executed method validation protocols and authored method validation reports.
  • Developed more than 30 Quality Control Validation Protocols of Critical Reagents.
  • Supported the Raw Materials by method development and writing validation protocols.
  • Reviewed method validation protocols and method transfers during the remediation process.
  • Wrote/reviewed validation protocols/reports, summary reports, and material specifications.
  • Participated in the validation protocols for method and instrumentation qualification.
  • Authored laboratory refrigerator and freezer validation protocols and final reports.
  • Reviewed and executed facility utility and downstream validation protocols.
  • Execute and contribute to assay qualification and validation protocols.
  • Author Process Qualification and method validation Protocols.
  • Write qualification/validation protocols for cell-based potency assay.
  • Prepared method validation protocols and reports.
  • Review data and write scientific documents like standard operating procedures, standard test methods, validation protocols, and validation reports.
  • Work closely with operation team to carry out batch transfers for new formulations and develop validation protocols for process improvements.

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21. GC

average Demand
Here's how GC is used in Scientist jobs:
  • Received special recognition for successfully developing GC methods for determination of residual solvents in drug substances.
  • Review data from GC/MS, LC/MS, GC/FID, HPLC, and IC for compliance with regulatory and client specified standards.
  • Perform analysis for Stability group using HPLC, GC, UV, FTIR and other chemical analysis relating to stability.
  • Performed initial and final quality control reviews of clinical study results derived from HPLC, HRGC/MS, and LC/MS instruments.
  • Developed and optimized methods for analysis of oxidized lipids in biological matrices (HPLC, LC-MS/MS, GC).
  • Review manufacturing documents for the APTIMA CT and GC reagents and participate in the release of the assay reagents.
  • Conducted GC analysis on chemical pollutants in solid, gas and liquid samples following governmental and company procedures.
  • Performed analysis on and troubleshooting of instrumentation including ICP-MS, HPLC, GC, UV and FT-IR.
  • Performed testing and calibration of GC, Flame photometers, pH meters, and Electric Conductivity analyzer.
  • Train as a backup subject matter expert for GC and other instruments when lead chemists are unavailable.
  • Developed training programs for GC operation and for the safety and proper use of gas tanks.
  • Increased roles and responsibilities using GC, HPLC, and FT-IR in pharmaceutical and petroleum industries.
  • Analyze a variety of products and impurities using HPLC, GCMS, LCMSMS and NMR.
  • Validated methods following ICH guidelines using HPLC, GC, LCMS, and UPLC etc.
  • Analyze volatile organic compounds in serum sample and cyanide in whole blood sample using GC/MS.
  • Developed and validated LC-MS/MS and GC-MS methods for the analysis of small and large molecules.
  • Drug testing using AU 640 for preliminary testing and GCMS for confirmations along with HPLC.
  • Utilized FTIR, electron microscopy, EDAX, GC/MS, HPLC and wet chemical techniques.
  • Instrument operation and maintenance (IC, GC, HPLC and various spectroscopy).
  • Synthesized nicotine analogs under senior staff direction, verifying purity utilizing NMR and GC.

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22. QC

average Demand
Here's how QC is used in Scientist jobs:
  • Analyzed and Performed QC data to study synergistic/antagonistic or additive effects of drug combination using Assay Client.
  • Spearheaded and implemented routine laboratory and manufacturing environmental monitoring program in collaboration with QC department.
  • Performed the QC/quality compliance review of high quality scientific documentation from within the document repositories.
  • Supported general QC laboratory functions and assisted in the environmental monitoring of aseptic filling operations.
  • Lead and supported troubleshooting for complex investigations in the QC labs and manufacturing investigations.
  • Provided support to QC laboratory areas and also supported method validation/qualification and tech transfer.
  • Conduct QC on laboratory automation liquid handling instruments to ensure accuracy and precision.
  • Diagnose several QC concerns and implement additional manufacturing and quality control procedures.
  • Performed and documented routine QC analysis of all materials produced in-house.
  • Developed company s first QC protocols for chemically sensitive membrane technology.
  • Performed QC and maintenance on laboratory equipment.
  • Review Quality Control on all major laboratory instruments and provide necessary action and follow up on all QC related issue.
  • Instrument developments of Quantum Cascade Laser Spectroscopy (QCLS) and diode laser absorption spectroscopy to measure atmospheric trace gases.
  • Developed two non-radioactive Northern Analysis-based product release assays followed by tech transfer to the QC department and follow up support.
  • Operated 3100, 3130xl Genetic Analyzer using POP 4 and POP 6 polymers QC in an accurate and timely manner.
  • Reviewed and QC research data from external resources and collaboration, and recorded results and spreadsheet in electronic notebook.
  • Involved with generating AFE (Authorization for Expenditure) documents to purchase new equipment for the AQC laboratory.
  • Trained employees in the QC and Validation departments on product release assay and raw material release assays.
  • Teach, guide, train and mentor QC chemists as well as prepare and complete performance evaluations.
  • Maintained close interaction with manufacturing engineers, EH&S team, QC, and floor operators.

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23. Drug Products

average Demand
Here's how Drug Products is used in Scientist jobs:
  • Collaborated with Quality Assurance to transfer methods documents for drug products into Manufacturing Quality Control for validation of testing methods.
  • Performed qualitative analysis on drug products including bulk materials, in-processed and finished products.
  • Developed qualified preservation systems for cosmetic and OTC drug products for global market distribution.
  • Calibrated dissolution system as per USP requirement and performed dissolution for drug products.
  • Authorized release of drug products/materials for further processing to manufacturing and packaging.
  • Performed clinical release and stability testing on active ingredients drug products.
  • Performed routine characterization testing on residual drug products via Reversed-Phase HPLC.
  • Performed analysis of finished drug products as per stability protocols.
  • Established the stability of drug products for international registration.
  • Assessed decontamination/cleaning procedures for existing commercial drug products.
  • Analyze clinical and primary stability drug products.
  • Performed stability studies for pharmaceutical drug products.
  • Conducted root cause investigations of manufacturing problems and deviations in cases where drug products failed to meet client or regulatory expectations.
  • Implemented the LC-MS identity assay as a release test for 340+ drug products during Phase II and III clinical trials.
  • Perform LC/MS/MS method development, optimization and identification of unknown impurities or degradation products in drug substance or drug products.
  • Cultivated relationships with doctors, analysts, medical staff, and formulators to coordinate the distribution of technical drug products.
  • Designed, executed, and interpreted degradation studies to elucidate the chemical stability of drug candidates and drug products.
  • Code adverse events, medical history, laboratory results, drug products as required utilizing MedDRA and WHO-Drug dictionaries.
  • Develop and validate HPLC methods for determination of assay and related impurities in raw materials and finished drug products.
  • Supported R&D in Method Evaluation/Development, Method Validation of API, Drug Products formulations/process, scale-up manufacturing.

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24. Lims

average Demand
Here's how Lims is used in Scientist jobs:
  • Managed sample inventory via in-house laboratory information management system (LIMS) and implemented additional systems for sample and chemical organization.
  • Reported whole blood and chemistry analysis in the Clinical Pathology Information System (Laboratory Information Management System LIMS).
  • Utilized Oracle administration functions to assist in report development, LIMS configuration and system maintenance for quality data.
  • Documented experimental procedures and results and entered results into Laboratory Information System (LIMS) database.
  • Experience with internal proprietary LIMS system for automated data transfer to discovery database.
  • Captured all specimen and testing data accurately using StarLIMs.
  • Sample approval and verification utilizing Fusion LIMS system.
  • Possess excellent understanding of LIMS technology.
  • Developed and configured Empower/LIMS interface.
  • Conducted of technical documents such as test procedures, ATR for cleaning and release on GDMS, LIMS and ELN systems.
  • Write, revise and review protocols, reports, worksheets, LIMS design plans, training materials and Standard Operating Procedures.
  • Work with various software systems, including instrument software, LIMS, and databases for data calculation and report generation.
  • Research and develop Guidelines for the use and maintenance of the LIMS once the product is accepted by the Client.
  • Developed validated tool for controlling access to data files and reformatting data into SoftMax format for importing into Watson LIMS.
  • Conducted statistical analysis, recorded data in electronic files, and maintained accurate records in the computer database using LIMS.
  • Recorded sample results into the LIMS database, which tracks results, derivations, work load & lab supply usage.
  • Enter test results in electronic documentation, such as Laboratory Information Systems (LIMS) and SAP on time.
  • Planned, tested and implemented RJ Lee RLIMS software providing lab workload management tool for multiple laboratories.
  • Trained and mentored others in assay automation, instrumentation, assay qualification, LIMS, and ELN.
  • Acted as the LIMS and SAP resource person for the group training new employees on database operations.

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25. Assay Development

average Demand
Here's how Assay Development is used in Scientist jobs:
  • Performed various assay development related studies such as Specifications Determination, Verification and Validation for the final kit reagents.
  • Target validation, assay development, and assay coordinator for collaboration with Abbott Pharmaceuticals.
  • Analyze and interpret experimental results and design subsequent experiments to optimize assay development.
  • Contributed to assay development in analyzing protein quality for potential clinical trials.
  • Performed clinical testing and assay development using automated and manual assay techniques.
  • Performed new assay development, troubleshooting, data review and investigations.
  • Provided technical input in assay development and clinical sample testing efforts.
  • Major skills include protein expression purification, characterization and assay development.
  • Performed high throughput screening-assay development and small molecule screening.
  • Purified milligram quantities of protein used in assay development.
  • Assay development and implementation for high-throughput primary screening.
  • Supported assay development to strengthen purification characterization package.
  • Project manager for metabolic activation assay development.
  • Contributed in new assay development and implementation.
  • Conducted cellular assay development i.e.
  • Cell-based assay development and compound profiling
  • Led assay development team to develop assays for drug candidate screening in HIV, HCV and PK enhancer projects;.
  • Managed viral culture and assay development teams for a HHS/BARDA contract to develop a POC influenza antiviral susceptibility test.
  • Directed GPCR screening projects, from target discovery, assay development and library screening, to hits characterization.
  • Guide, mentor, and oversee junior scientists in designing assay development, routine testing, and training.

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26. LC

average Demand
Here's how LC is used in Scientist jobs:
  • Developed and performed methods for analysis of radio labeled organic pesticides through extensive HPLC and Liquid Scintillation techniques usage.
  • Validated/maintained HPLC equipment; responsible for all sections of method development/validation; provided assistance to co-workers with their projects
  • Developed the sample cleaning methods by using solid phase extraction for LC/MS/MS analysis and impurity identification.
  • Designed laboratory reagents including calculation of batch quantities, concentration, and dilution factors.
  • Performed basic cataloging in non-MARC catalog using LC classification and processed all library materials.
  • Developed and validated antibody drug conjugates characterization methods by LC-MS and MADI-TOF.
  • Have calculated seasonal variations of the solar radiation falling onto parabolic-cylindrical antennas.
  • Performed HPLC method development and validation for multiple active ingredient formulation products.
  • Performed method development and validation for Cleaning Validation by HPLC analysis.
  • Performed critical metabolic studies including CYP inhibition and induction utilizing LC/MS.
  • Calculated and prepare laboratory test report within established working schedule.
  • Performed original and copy cataloging using OCLC and DDC classification.
  • Performed LC-MS/MS based characterization of sequences for protein identification.
  • Perform calculation of active, detergent and microbiological residues.
  • Developed many HPLC cleaning/residue methods and coordinated method transfer.
  • Developed HPLC methods to determine antibody conjugation efficiency.
  • Supported annual budget calculation for Chemical Laboratory.
  • Write patent procedures for projects, collected and interpreted data information such as LC/MS, 1H NMR, 13C for patents.
  • Performed peer review on other analysts' notebooks, HPLC, and loose data records for method validations or stability testing.
  • Characterized the binding of small molecular weight drug candidates to target proteins using HPLC combined with MS analysis of collected fractions.

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27. API

average Demand
Here's how API is used in Scientist jobs:
  • Designed experiments to optimize 4cast technology in order to for products to be produced more rapidly and efficiently for commercial manufacturing.
  • Developed a lateral flow rapid manual diagnostic test with an instrumented read out for anthrax protective antibody to promote personalized vaccination.
  • Provided expertise in troubleshooting processes and instrumentation at a company-wide level, justifying capital equipment, and identifying future process developments.
  • Specialized in developmental testing for early phase drug API, including atomic absorption spectroscopy, and pharmacopoeia monographs.
  • Worked on feasibility of an innovative rapid assay for detection of Gram-negative susceptibility direct from patient sample.
  • Developed thermal treatment of tobacco for a rapid flavor and texture development for smokeless tobacco production.
  • Designed and executed an animal protocol for evaluation of alternative therapies for wounds.
  • Performed SFC methods development and validation for API release and stability evaluations.
  • Coordinated with Global Operations on maintenance of building equipment and capital improvements.
  • Assisted physical therapists in creating rehabilitation training programs for injured players.
  • Maintained documentation for Qualification and API lots and all applicable analyses.
  • Implemented guidance and instruction on scientific and administrative issues for therapists.
  • Developed a rapid 15 minute PCR-based method for pathogen identification.
  • Contributed to development of rapid diagnostic tests for sexually transmitted diseases
  • Formulated a product line of rapid-cure epoxy thermal interface adhesives.
  • Provided toxicity study design support for drug infusion therapies.
  • Researched and developed new product technology for rapid diagnostic systems
  • Identified raw material and capital needs at manufacturing facilities.
  • Developed rapid melt formulations with consumer acceptable sensory experience.
  • Developed binding protocols for NanoPrep capillary isolation amplification system.

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28. Technical Reports

average Demand
Here's how Technical Reports is used in Scientist jobs:
  • Designed experiments and conducted statistical analyses, authored and executed protocols, performed data trending and summarized results into technical reports.
  • Create detailed technical reports that include recommendations for impact reduction and alternative construction methods and techniques for minor and major facilities.
  • Prepare written technical reports documenting investigations, permit reviews, consistency reviews, report reviews or monitoring activities.
  • Prepared multiple internal technical reports for management, and presented data to outside scientific advisers and collaborators.
  • Analyze stability data and write technical reports for comparability and setting shelf-life for clinical and commercial products.
  • Author technical reports documenting assay validation studies and lab studies including development/optimization and method performance investigations.
  • Prepared development proposals, executed protocols, and generated technical reports and regulatory submission documents.
  • Evaluate and complete validation requests, obtain validation certifications and write technical reports.
  • Generated technical reports from all laboratory testing performed and collected supporting data recorded.
  • Prepared technical reports, summaries and quantitative analyses and maintained complete/accurate records.
  • Draft and review technical reports for internal presentations and regulatory submissions.
  • Prepared technical reports after the completion of projects for documentation.
  • Authored test procedures/protocols, method development reports and technical reports.
  • Issued detailed technical reports and published manuscripts based on analysis.
  • Authored technical reports summarizing results, findings and recommendations.
  • Composed technical reports documenting validation activities and results.
  • Produced technical reports and manuscripts for peer-reviewed publication.
  • Generate technical reports and documentation for NME submission.
  • Authored corporate Quarterly Reports and Technical Reports.
  • Analyzed experimental data and wrote technical reports.

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29. Cros

average Demand
Here's how Cros is used in Scientist jobs:
  • Flexed labor to other groups when necessary to provide additional capacity, cross-training for increased capacity and to relieve workload imbalance.
  • Designed and Developed a microscopy-based assay to visualize multiple protein complexes simultaneously in intact cells, using Proximity Ligation Assay technology.
  • Designed and implemented physical and microscopic analyses of components and raw materials enabling accelerated battery production and R&D output.
  • Created a functioning Microsoft Access based inventory control database, designed to improve the organization of operations in the laboratory.
  • Implemented deep data mining across hundreds of processes with right filter design to understand complicated interaction of process integration.
  • Collaborated with cross-functional groups and international colleagues to complete highly complex and business-critical projects on time and within budget.
  • Assisted in redesigning an efficient routine calibration process across the department and established an updated protocol for remedial maintenance.
  • Received certification as a Biological Electron Microscopy Technologist from the Microscopy Society of America, certificate #2034.
  • Achieved cross-training in multiple laboratory departments to acquire knowledge of material analysis, metals, and environmental labs.
  • Performed microscopy analysis on chromosomes for diagnostics and prognostics examination for patients referred for oncology and reproductive evaluations.
  • Collaborated on a regular basis with colleagues across different departments to advance multiple projects toward key objectives.
  • Lead a team consisting of representatives from each Pharmaceutical Development department towards safety efforts across multiple departments.
  • Developed and managed a database using Microsoft Access for ecosystem evaluation of different species in Hudson River.
  • Collaborated with cross-functional scientists and contributed to technology investigation studies, such as new drug substance formulations
  • Monitored radiation safety across departments to insure compliance with established state and federal guidelines.
  • Presented findings at meetings and publications, set up collaborations across different functional areas.
  • Led an international cross functional team in consolidating processing plants and increasing processing efficiency.
  • Contributed significantly to the business development of the online market intelligence division of Microsoft.
  • Collaborate within and across teams including participation and leadership in committees and initiatives.
  • Maintained design history file documentation for various assemblies across multiple engineering disciplines.

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30. Biology

low Demand
Here's how Biology is used in Scientist jobs:
  • Planned and completed experiments utilizing molecular biology, cell biology and biochemistry techniques to discover and develop novel neurological disease targets.
  • Participated in the investigation in the biology of muscle degenerative diseases and regeneration for the development of insulin-like therapeutic agents.
  • Performed new method development using literature search and molecular biology techniques for the toxicology research (Drug Safety Evaluation).
  • Evaluated new targets, studied competitive landscape, biology and potential commercial applications and presented target evaluation to management.
  • Distribute Monthly stability report to QA Laboratory, Chemistry and Microbiology, Ensure all testing performed by appropriate laboratories.
  • Used molecular biology and microbiology to identify organisms present and clone sequences of interest for protein expression systems.
  • Collaborate with other scientists in epidemiology, environmental medicine, toxicology, systems biology, and homeland security.
  • Served as Computational Biology Subject Matter Expert to evaluate multiple external target and technology licensing opportunities.
  • Established a company focused on providing histology and molecular biology services to the biotechnology industry.
  • Established a new laboratory of molecular biology for drug development, drug screening and evaluation.
  • Developed a strong understanding of Microbiology, Genetics, Molecular Biology and Host-pathogen interaction.
  • Develop technical procedures to characterize novel entities and address relevant disease area biology questions.
  • Collaborate closely and effectively with colleagues in biology group and across other departments.
  • Prepared the biology and pharmacology sections of a slide presentation for potential investors.
  • General microbiology (bacteria identification and isolation from skin, media preparation).
  • Generated quantitative PCR and molecular biology data used in several prestigious journal publications.
  • Attended scientific conference (American Society for Microbiology) and presented publication.
  • Assisted in ongoing tumor biology research projects and in general laboratory management.
  • Established and optimized molecular biology protocols for automation and high-throughput applications.
  • Provided microbiology subject matter expertise to chemical and biological defense programs.

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31. Drug Discovery

low Demand
Here's how Drug Discovery is used in Scientist jobs:
  • Developed and optimized procedures for protein purification and scale-up supporting drug discovery; Participated in bacterial and insect cell fermentation.
  • Participated in a team of Directors who evaluated new targets to prioritize for in-house validation and/or drug discovery activities.
  • Represented pharmaceutical department in multiple drug discovery project teams to provide pharmaceutical input in facilitating candidate identification and nomination.
  • Developed imaging applications and analysis for cellular and tissue systems in support of drug discovery and toxicology studies.
  • Aided in drug discovery project; assessed metabolic stability of various compounds and delivered training on technique.
  • Provided product with high purity and quantity based on customer's drug discovery and development application requirement.
  • Led drug discovery projects that involved exploring chemical matter for different disease targets.
  • Led multidisciplinary teams and developed new automated assays to facilitate drug discovery efforts.
  • Provided scientific and technical expertise at lead optimization stage for antibacterial drug discovery.
  • Developed novel tools for drug discovery and development in academia and industry.
  • Designed and led drug discovery research programs for anti-microbial and gastrointestinal therapies.
  • Designed and implemented rodent behavioral pharmacology models for CNS drug discovery projects.
  • Participated in the delivery of five therapeutic antibody drug discovery programs.
  • Supported and perform the many laboratory processes involved in drug discovery.
  • Lead and establish technology and application for drug discovery and development.
  • Optimized purification methods to deliver high quality compounds for drug discovery.
  • Designed and synthesized novel compounds to populate oncology drug discovery pipeline.
  • Performed immunological assays using ELISA for drug discovery.
  • Participated in a highly integrated drug discovery program.
  • Identified and validated novel targets for drug discovery.

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32. RNA

low Demand
Here's how RNA is used in Scientist jobs:
  • Co-authored publications in research journals and presentations at scientific conferences; prepared reports for pharmaceutical companies, medical associations and clinicians.
  • Established and maintained effective network of external experts and collaborators to support research to maintain & utilize leading edge capabilities.
  • Constructed master and working cell banks for internal and external laboratories enabling continuous supply of cells used domestically and abroad.
  • Developed a diffusion process using a specially designed IR furnace that yielded higher product throughput while maintaining comparable device efficiency.
  • Interacted with external collaborators, trained and supervised students on various equipment and procedures, prepared research reports and publications.
  • Traveled nationally and internationally to customer sites for complaint investigations, troubleshooting, issue resolution and customer relations.
  • Designed measurements for the studies of alternative energy storage methods and receiver configurations for the solar power industry.
  • Focused on fed-batch fermentation techniques, building out internal capital as needed to support fermentation process development.
  • Summarized experimental results in a memo or developmental report, and presents the results internally and/or externally.
  • Prepared structural analogs of potential new drug candidates, developing new procedures or alternative syntheses as necessary.
  • Developed and presented oral presentations to internal and external audiences on Electronic Health Records and Meaningful use.
  • Developed a binding experiment utilizing fluorescence polarization to screen discovery compounds for interaction with various RNA constructs.
  • Researched and proposed optimal inventory strategy and use strategic thinking to suggest alternate inventory locations and shippers.
  • Ensured accuracy of data by overseeing instrument maintenance and repair, including both internal and external servicing.
  • Developed and maintained strong business relationships with internal / external groups to ensure validity of product stability.
  • Prepared laboratory reagents according to production schedule for internal use and for shipment to external customers.
  • Conducted research and collaborated with a variety of internal and external stakeholders to accomplish business goals.
  • Develop and implement project plans and protocols for internal and external clinical evaluation of diagnostic products.
  • Coordinated method design of and validation while authoring protocols and reports; coordinated international technology transfer.
  • Introduced a method for improving NGS library quality through optimized segregation of RNA-bound purification beads.

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33. Clinical Trials

low Demand
Here's how Clinical Trials is used in Scientist jobs:
  • Provide statistical expertise to design clinical trials, define and execute analyses and interpret statistical results.
  • Develop and validate anti-drug antibody assays for protein therapeutics for clinical trials in GxP lab
  • Conducted method validations and clinical trials for rapid
  • Collaborated with cross-functional teams that consist of regulatory specialist, engineers, and scientists to plan towards clinical trials in 2014.
  • Lead clinical candidate, VX-497, identified in just under 18 months reached Phase II clinical trials for Hepatitis C infection.
  • Provided critical information that was used to select 4 candidate drugs for progression to clinical trials and submission of IND applications.
  • Used object-oriented techniques to program the model into a simulator; validated the disease model against known clinical trials.
  • Collaborated with an external vendor, which resulted in a program lead compound to enter Phase I clinical trials.
  • Work very closely with other departments to advance drug candidates from discovery through regulatory submission & clinical trials.
  • Involved in antigen potency and stability testing of yellow fever vaccines presently in phase II clinical trials.
  • Performed analysis of clinical trials samples (PI/PII) to evaluate acute drug activity on PNP enzyme.
  • Assisted with method development, method validation and sample analysis to support nonclinical and clinical trials.
  • Educate parents of children with SMA and new industry partners on the ongoing SMA clinical trials.
  • Managed in-process and R&D stability sample testings and finish product releases for clinical trials.
  • Authored and archived meeting minutes, in addition to creating data entry instructions for clinical trials.
  • Support clinical trials to collect field testing data and understand user needs for continuous product improvement.
  • Conduct validation studies, clinical trials, and proficiency testing on behalf of our clients.
  • Developed novel methods and materials used in clinical trials for the management of HIV-1 infection.
  • Job Description: Evaluation and processing of safety data from clinical trials and marketed products.
  • Provided support during study design, start up, conduct and close-out of clinical trials.

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34. QA

low Demand
Here's how QA is used in Scientist jobs:
  • Conducted annual QA audit of contract manufacturer: as audit team member, identified manufacturing-relevant issues.
  • Performed administrative procedures to generate/amend controlled methods and protocols for future QA audited analyses.
  • Contribute to laboratory QA/QC monitoring and CDC data review and documentation.
  • Conducted internal QA of shipping manifests versus Watson logging information.
  • Performed QA CAPA root cause analysis for laboratory investigations.
  • Developed QA methodology to detect critical design engineering errors.
  • Reviewed all fermentation records and QA compliance documentation.
  • Analyzed hundreds of samples weekly, ensuring samples were run within appropriate hold times and in adherence to established QA/QC standards.
  • Lead clinical study approval process and ensure all required QA, IRB and Safety approvals are complete prior to study release.
  • Performed multidisciplinary team works with research, sales, QA, standard operation procedure (SOP), training and customer-service.
  • Assisted with quality assurance (QA) including paperwork review, weekly site evaluations, external audits, and audit responses.
  • Developed and optimized medical device equipment for point-of-care diagnostics, performed testing, QA and QC procedures, wrote technical documentation.
  • Communicated with laboratory staff, QA and clients and troubleshooted problem projects and processes, conducted OOS and CAPA investigations.
  • Observe and record temperatures of fridges, freezers, incubators, and water baths on daily bases for QA purposes.
  • Coordinated QC/QA efforts resulting in net reduction of deviation backlog from over 260 to less than 5 within four months.
  • Worked with Quality Assurance (QA) and CMC department in notebook, data, document review and lab auditing.
  • Coordinated phase 1 trial support between Medical Affairs, Pharmaceutical Development, QA and QC, and Regulatory Affairs.
  • Accrued experience in review for RCRA cases which required a thorough knowledge of QC/QA applied to SW 846 Methods.
  • Managed qualification testing of materials by working with Regulatory, Toxicology and QA based on DPI and PQRI guidance.
  • Serve as technical project manager and work in conjunction with QC/QA to ensure that reports/audit deadlines are met.

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35. Flow Cytometry

low Demand
Here's how Flow Cytometry is used in Scientist jobs:
  • Designed and implemented key functional cell based assays using FACS/Flow cytometry.
  • Assessed cell-surface expression of VLP vaccine target-proteins using flow cytometry.
  • Developed methods for validation and analysis of conjugates using spectroscopy, flow cytometry, SDS PAGE, ELISA and Western Blots.
  • Provided technical assistance for a panel of reagents ranging from flow cytometry, Western blotting, ELISA and other antibody-based methodologies.
  • Flow cytometry analysis of extracted lymphocytes from blood of patients in (CCTRN) clinical research study trials.
  • Manage research activities and development of Research Associates, external projects with CRO and flow cytometry facility.
  • Collaborate with Cell Line Development and Downstream Processing for ELISA, Flow Cytometry, and Validation Assays.
  • Performed QC of reagents for immune assays, such as flow cytometry and ELISA.
  • Developed ELISA and flow cytometry assays to evaluate overall immune responses to antigens.
  • Flow Cytometry labeling, sorting, and cell-cycle analysis (Abstract 1.2.3.10.)
  • Supported all flow cytometry and cell sorting for the stem cell lab.
  • Implemented thorough criteria for samples analysis of Attune NXT flow cytometry studies.
  • Set up new off-site tissue culture facility including flow cytometry core.
  • Trained team members in flow cytometry and supported other team efforts
  • Quantified tumor cell metastasis to bone marrow with flow cytometry.
  • Double fluorescence labeled antibody for flow cytometry analysis, 3.
  • Flow Cytometry instructor for internal users and projects support.
  • Characterize cell types and by flow cytometry.
  • Optimized the conditions for higher antibody production by numerous hybridoma lines using GMD secretion assay and flow cytometry sorting.
  • Optimized numerous antibodies for microscopy, microplate-based and flow cytometry assays, including labeling of embryonic tissue for microscopy.

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36. IND

low Demand
Here's how IND is used in Scientist jobs:
  • Counseled inexperienced colleague about purchased industry solutions to avoid costs associated with preparation and disposal of solutions with no stability data.
  • Advised and aided Safety and Health in developing methods of analysis for volatile organic vapor from industrial hygiene personnel monitor badges.
  • Designed and developed molecular and cellular assays to identify biological actives for skin whitening and anti-aging market of the cosmetic industry.
  • Search scientific publications and databases for novel ingredients, metabolic pathways, physiological functions, contraindications, and regulatory status.
  • Monitored reporting of adverse events, surveillance of the safety/efficacy of oncology products and updated annual IND report submissions.
  • Participated in manufacturing process investigations providing scientific rationale in order to find the root cause of the different situations.
  • Demonstrated ability to work independently, and with a multidisciplinary team, in a fast paced drug development environment.
  • Performed competitive binding vs. ATP, reversibility, receptor binding assays and time-dependent experiments to determine molecular inhibition mechanisms.
  • Developed, designed and fabricated test model of an industry stack pollutant detection and pollutant concentration recording system.
  • Drafted, filed and prosecuted patent applications in India and provided counsel support for drafting collaborative research agreements.
  • Perform moderately complex laboratory activities with limited supervision including, planning and performing individual experiments and new tasks.
  • Analyzed experimental results and presented the information to individuals within the research department and manufacturing divisions of ADM.
  • Supervised direct and indirect reports, including technical training, guidance for method development and troubleshooting.
  • Performed analysis and prepared intricate substantive study reports detailing methodologies, findings, and recommendations.
  • Worked independently on high-voltage particle trap designed to capture and analyze particles using spectrometer.
  • Prepared business cases and conducted business presentations; clearly communicated findings to Management.
  • Climbed wind turbines to maintain bat acoustic monitoring equipment and conducted fatality searches.
  • Documented relationship connections between individual wildlife species and plant communities and critical habitats.
  • Performed method development and validation on stability indicating assays following all regulatory guidelines.
  • Conducted independent research and directed multiple projects along with other senior scientists.

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37. Technical Support

low Demand
Here's how Technical Support is used in Scientist jobs:
  • Provided expert technical support to present and potential customers and other interacting collaborators remotely or via on-site visits with sales executives.
  • Provide technical support for test development and validation, test transfer, test trouble-shooting, laboratory investigations, and failure investigations.
  • Provided technical support to the office on projects ranging from initial site assessments and characterization through remedial action implementation.
  • Project lead for technical support and troubleshooting assays as well as method harmonization across multiple sites on international assignments.
  • Provide technical support for projects pertaining to national security and environmental stewardship directorates at the Savannah River Site.
  • Assessed, troubleshot and improved experimental protocols and technical supports to increase fermentation system efficiency and productivity.
  • Provided ongoing biological and technical support to foreign manufacturing sites to harmonize operating procedures and statistical data.
  • Provided technical support to formulations and production departments during product development and post validation stages.
  • Provided technical support on the instrumentation application and collaborated with universities on technology transfer.
  • Provided technical support during production of experimental and clinical batches using Drug Master Files.
  • Developed sampling approaches for EPA Technical Support Project geological site investigations.
  • Mentored employees and provided technical support for other departments and manufacturing.
  • Provided technical support and coordination within DoD and Intelligence Communities.
  • Provide technical support to investigation and resolution of process deviations.
  • Collaborate with technical support and medicinal chemistry function group.
  • Managed scientific and technical support for cell product characterization.
  • Maintained equipment provided technical support to senior staff.
  • Provided technical support on quality related matter.
  • Provide technical support and arrange technology transfer.
  • Provided technical support to update specifications.

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38. Ftir

low Demand
Here's how Ftir is used in Scientist jobs:
  • Operated FTIR analyzing a wide variety of oils, greases, raw materials, and chemical compounds used in production.
  • Utilized FTIR, GPC, and wet chemistry techniques to perform tests and get results.
  • Identified particles found during the manufacturing process and/or in final product using FTIR spectroscopy.
  • Created a library of FTIR spectra for materials used in the manufacturing process.
  • Created and developed FTIR Libraries that are used for troubleshooting production problems.
  • Generate data for foreign matter investigations using microscopy, DSC and FTIR.
  • Performed testing of Raw Materials following USP, BP (FTIR, KF, LOD, and Particle Size).
  • Developed Automated Control of Crystallization via FTIR for Paracetamol and other APIs.
  • Performed ID test on raw materials using FTIR * Wrote Investigations for failing results that were Out of Specifications.
  • Performed performance verifications on new instrumentation (HPLC, RI detector, ELSD, FTIR and AA).
  • Analyzed samples using FTIR, UV-Vis and specific rotation.
  • Performed identity test of excipients by FTIR.
  • Support analyst for FTIR, and Galvanostat.
  • Performed routine and non-routine analytical testing utilizing latest analytical techniques including DSC, TGA, UV-Vis, FTIR, and microscopy.

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39. Data Collection

low Demand
Here's how Data Collection is used in Scientist jobs:
  • Managed operation and validation of computer systems used in Reproductive Toxicology resulting in increased efficiency in data collection and analysis.
  • Eliminated unnecessary data collection and reduced transcription errors, resulted in reduced review time and fewer quality audit findings.
  • Developed standard operating procedures and data collections for a liquid-liquid extraction, and ion exchange column.
  • Conduct underwater research based on funded federal proposal scope involving data collection and coral transplants.
  • Conducted dietary interviewer training sessions and certification of field staff in nutrition data collection methodology.
  • Planned and assisted research meetings to design experiments for data collection and analysis.
  • Managed the data collection, investigations and data presentation for individual studies.
  • Designed and conducted drug development experiments, performed data collection and analysis.
  • Performed quality assurance and quality control on data collection and testing methods.
  • Supervised coordination of study set-up and management of data collection software.
  • Reported findings, and assisted with metadata collection for database ingestion.
  • Provide feedback on independently run experiments to improve data collection protocols.
  • Assisted in data collection for FDA regulatory documents and peer-reviewed publications.
  • Managed GIS data collection and analysis for multidisciplinary research team.
  • Utilized Empower for instrumentation setup and data collection.
  • Experienced in data collection and interpretation.
  • Performed data collection and analysis.
  • Provide adverse event case processing for clinical and spontaneous cases including case data collection and entry into global data base.
  • Coordinated and conducted wildlife census data collection on species such as deer, alligators, river otters and others.
  • Specialized in the collection of squid samples including: jigging, dissecting, data collection and species identification.

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40. Research Projects

low Demand
Here's how Research Projects is used in Scientist jobs:
  • Contributed to sponsored research projects in assorted capacities such as engineering design, project planning, design documentation and team management.
  • Collaborated on research projects with University research teams - Facilitated technology transfer between academia and industry - Mentored graduate and undergraduate students
  • Provided potential antibacterial drugs and immune system suppressants for biological evaluation in support of four research projects.
  • Planned, designed, conducted and supervised several research projects involving ruminant nutrition and forage evaluation.
  • Managed assigned research projects; collaborated with pathologists, research scientists and external business partners.
  • Participate in special research projects to support formulations research, pharmacology, and toxicology.
  • Conducted research projects related to antigen design and antibody development and production.
  • Be responsible for contributing to organic chemistry and medicinal chemistry research projects.
  • Supported research projects using NMR spectroscopy, specifically nicotine analog programs.
  • Command the programmatic and financial development of all collaborative research projects.
  • Conducted independent research projects to identify potential new products.
  • Developed and proposed research projects throughout area of responsibility.
  • Initiated discovery research projects and performed process improvement studies.
  • Developed laboratory methods and research projects for early-stage drug discovery
  • Managed several concurrent research projects.
  • Managed research projects delineating the function of the Wiskott-Aldrich Syndrome Protein (WASP) in T cells and immunity.
  • Project Management: Responsible for the design, management, and oversight of both personal and undergraduate research projects.
  • Collaborate with in-house teams to ensure timely progress in research projects, projects prioritization and resource allocation.
  • Synthesized small molecules and designed synthetic routes for ongoing research projects -Presented progress reports in meetings with clients
  • Completed over ten medicinal chemistry research projects successfully and got promotion from Scientist I to Scientist II.

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41. ISO

low Demand
Here's how ISO is used in Scientist jobs:
  • Performed Quality Control of assay kits providing supervisor analysis and insight for stability and optimal conditions for such assay kits.
  • Develop product and process specifications, process validation, technical justifications, formula comparison and development & marketing stability reports.
  • Designed and executed presentations at all levels including management meetings, scientific advisory board and board meetings.
  • Participated and provided technical assistance in complex investigations, method transfer, method comparisons and method validation.
  • Perform synthesis, isolation and characterization of intermediate degradation products, impurities and side products.
  • Specialize in Cognitive/Behavioral Interventions for anxiety and other behavior disorders in adolescents and adults.
  • Performed Dissolution Comparison Studies for new hormonal formulations between Type-I and Type-II apparatus.
  • Experienced in metabolic engineering technology at the CMO company owned by my supervisor.
  • Synthesized a novel series of 6,7-dimethoxyisoquinoline analogs as potent and reversible GFAT inhibitors.
  • Serve as a statistical expert on a high-profile internal/external Agency advisory panel.
  • Developed molecular genetic assays for characterization and diagnosis of human genetic disorders.
  • Key liaison in the maintenance of active scientific collaboration with Millennium Pharmaceuticals.
  • Self-motivated and independent work carried out with minimal contact from supervisor.
  • Developed in-house environmental isolate retention/inventory program to comply with USP requirements.
  • Maintain proper laboratory practice and experimental documentation to ISO 13485 standards.
  • Communicate effectively with team members and supervisors regarding work-related challenges.
  • Recorded all radioisotope usage/storage and maintained buffers and stock solutions.
  • Supported dissolution studies for competitor comparison of dissolution profile curves.
  • Functioned as liaison between department of quality control/assurance and research/development.
  • Designated scientific and technical liaison to external manufacturing partners 5.

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42. Sds-Page

low Demand
Here's how Sds-Page is used in Scientist jobs:
  • Determined antigen/antibody purity and characteristics by SDS-PAGE and Western Blots.
  • Used qualitative and quantitative techniques to characterize proteins, including SDS-page, imaging, Western Blot, ELISA analysis and spectroscopy.
  • Supported the oncology therapeutic area by characterizing multiple cell lines using imaging, SDS-PAGE and Western blotting.
  • Performed troubleshooting of SDS-PAGE and western blot for other scientists when results were not as expected.
  • Utilized reverse-phase HPLC and SDS-PAGE methods to characterize impurities in drug substance samples.
  • Conjugated small molecules with proteins, prepared markers for SDS-PAGE using Western Blot.
  • Assessed protein activity and function through SDS-PAGE, western blot, and ELISA.
  • Mastered techniques: SDS-PAGE analysis, Protein Assays, Purification using AKTA systems
  • Performed protein detection-SDS-PAGE gels, western blots.
  • Perform ELISA, Western blot, SDS-PAGE.
  • Involved in validation and implementation of Agilent TapeStation technology to increase in process resolution of SDS-PAGE during purification of Tissue Factor.
  • Utilize SEC, electrophoresis (Zonal, IEF, SDS-PAGE), and Western blotting for qualitative and quantitative assessments.
  • Separated and analyzed purified VLP vaccines by SDS-PAGE and protein staining; quantitated yield by Bradford protein assay.
  • Provided extensive SDS-PAGE, Autoradiograph and Western Blot experience, in addition to being BLS2 trained.
  • Review of In-Process Testing Laboratory Results for a biological product (SDS-PAGE, Antibody Column Assays, and Spectrophotometry).
  • Developed, implemented and characterized products such as labeled fluorescent antibodies, immunoblot IR washing buffer, precast SDS-PAGE gels.
  • Completed SDS-PAGE analysis using Excel Gradient Gels and Tris-Glycine "Mini-Gels" for identity and purity testing.
  • Characterized purified protein via SDS-PAGE, mass spectrophotometry and UV spectrometry.
  • Performed analytical testing such as: UV-Vis Spectroscopy, SDS-PAGE, IEF, pH, Osmolality, Particulate Matter.
  • Developed methods for biomarker characterization using SDS-PAGE, western blot, qPCR, and biological assays.

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43. NMR

low Demand
Here's how NMR is used in Scientist jobs:
  • Expressed and purified enzymes (oncology and diabetes projects) for ALIS screening, NMR and X-ray.
  • Developed methods for NMR compound library screening, and performed compound fragment library quality control.
  • Analyzed new chemical entities using NMR and LC-CLND-MS, supporting biologists in their targeted research.
  • Characterized synthesized products using TLC, NMR, solid state NMR, FTIR and LC/MS.
  • Identified and elucidated the chemical structure using 1H NMR, 13C NMR and LC-MS.
  • Analyzed and monitored the synthetic process using HPLC, NMR, LC-MS and TLC.
  • Maintained a 250 and 400 MHz NMR through weekly fills with liquid nitrogen.
  • Conducted 1D and 2D NMR studies for structure determination of complex molecules.
  • Purified and labeled various proteins to support NMR and X-Ray studies.
  • Characterized compounds and determined purity by LC/MS and NMR techniques.
  • Established an organic lab and proposed and purchased 200MHz NMR.
  • Analyzed QA compounds by NMR spectroscopy prior to pharmacological testing.
  • Process, evaluate and improve NMR logs.
  • Characterized the compounds by 1H NMR, 13C NMR and LCMS.
  • Analyzed results from MALDI-Mass Spectrometry and generated NMR Spectroscopy data for characterization of polymers.
  • Synthesized bio-molecules and characterized using 1D/2D NMR spectroscopy and mass spectrometry.
  • Investigated mechanism of chiral separation using NMR.
  • Job responsibilities were the same as prior listing since NMR division was purchased by Oxford Instruments in April, 2005
  • Used reversed phase HPLC for purification of drug metabolites and Mass Spectrometry and NMR for structure identification.
  • Worked on the characterization of peptides-small molecule complexes with western blot, MALDI-TOF, and NMR.

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44. DOE

low Demand
Here's how DOE is used in Scientist jobs:
  • Involved in optimization, laboratory validation and reaction characterization of various processes using DOE (design of experiments).
  • Collected experimental data with an application of DOE methodology defining critical process parameters (CPP).
  • Process development and improvement of new antibiotics and antibiotic intermediates using DOE methods.
  • Participated in DoE of developmental/qualification and validation protocols & reports.
  • Assisted in development of products by applying principles of design of experiment (DOE) and analyzing data using statistical techniques.
  • Process development for the coating of matrix patch and identify the critical process parameter and identify with help of DOE.
  • Field Operations Supervisor for an RFI conducted at a U.S. Department of Energy (DOE) uranium enrichment facility.
  • Establish statistical process controls (SPC) & design-of-experiment (DOE) methodologies for cross-module process development and optimization.
  • Perform design of experiment (DoE) studies on various formulations using MiniTab to determine dependencies of multiple variables.
  • Contributed in writing several SBIR/STTR proposals for government funding agencies (DOD, DOE, and NSF).
  • Developed and implemented quality plan for lab operations in accordance with DOE Order QC-1 and ISO 17025.
  • Experience with Design of Experiments (DoE) and high throughput screening method for downstream process development.
  • Utilized commercially available media, media supplements and feeds to optimize cell culture processes using DOE design.
  • Provided technical directions and guidance for research methodologies, DOE to support a Proof-of Concept and scale-up.
  • Utilized DOE for formulation screening and SPC (statistic process control) for QA/QC in production
  • Performed Design of Experiment (DOE) studies to add statistical strength to experimental data.
  • Compiled methods, analyses of DOE, and conclusions into reports for client presentations.
  • Utilized DOE(Design of Experiment) with DesignExpert software to analyze mixture design.
  • Design of Experiment (DOE) to streamline development and shortening robustness studies.
  • Team leader of DOE mandated Highly Enriched Uranium Vulnerability Assessment for the INL.

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45. Small Molecules

low Demand
Here's how Small Molecules is used in Scientist jobs:
  • Elucidated the molecular mechanism of cancer cell drug resistance in response to small molecules modulating nuclear receptor signaling pathways.
  • Developed and validated molecular and cellular screening assays for small molecules utilizing various technologies.
  • Utilize biophysical technologies to investigate binding of small molecules to proteins.
  • Research efforts directed toward the development of potent, novel small molecules for testing in various programs in women's health.
  • Established and characterized select humanized SCID mouse models for advancement of small molecules through select projects.
  • Support project teams through weekly screening of small molecules in various types of kinetic assays.
  • Performed High-throughput screening (HTS) of small molecules (ALIS hits).
  • Synthesized small molecules bacterial enzyme inhibitors on the basis of SAR studies.
  • Performed chronic xenograft studies for characterization of select small molecules and antibodies.
  • Design and synthesize small molecules on a gram scale for the development of forensic toxicology immunoassays against illicit drugs of abuse.
  • Discovered new method for conjugation of small molecules to antibodies leading to US Patent: WO [ ] Conjugation methods.
  • Received a Patent for inventing a new way to remove particulates and small molecules from mammalian cell lysate.
  • Studied the development of small molecules in disease processes and the potential therapeutic / diagnostic applications.
  • Carried out and led high-throughput screening efforts of small molecules towards drug development in de-ubiquitinase pathway.
  • Designed and synthesized various small molecules, protection and deprotection strategy, coupling reactions, etc.
  • Developed LC-MS/MS methods for challenging infection compounds-small molecules and small peptides.
  • Supported oncology nonclinical development programs & submission of two small molecules and one antisense oligonucleotide IND.
  • Conjugated bioactive small molecules to proteins for oncologic applications.
  • Interfaced with biologists and chemists to develop and implement mass spectrometric methods for the detection of small molecules and peptides.
  • Developed colorimetric assays for small molecules, proteins, and enzymes in microtiter plate formats.

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46. Batch Records

low Demand
Here's how Batch Records is used in Scientist jobs:
  • Provided support for preparation of technical documents such as Manufacturing batch records.
  • Review manufacturing batch records against validated process and specifications for discrepancies.
  • Prepare experimental master batch records and train manufacturing staff.
  • Reviewed and authorized reports/documents such as product development reports, batch records, data, master formulas and other key documents/reports.
  • Prepared Master Batch Records for pilot plant production - coordinated with engineering, environmental, safety, and compliance departments.
  • Provide Quality Assurance support to Supply Chain by review of packaging batch records new SOP's, and quality investigations.
  • Reviewed and released batch records for finish products, intermediates, Active Pharmaceutical Ingredient (API) and raw materials.
  • Prepare protocols and batch records to carry out product development activities from the lab scale to pilot scale.
  • Revised established batch records and documented original R&D data to author batch records for new projects.
  • Prepared Manufacturing Batch Records, Packaging Batch Records for Exhibit Batches, Commercial Batches and related documentation.
  • Reviewed all batch records and maintained quality control on all related batch data and information.
  • Reviewed Batch Records processed by team members as a means of local Quality Control.
  • Group lead and contact for streamlining and updating SOP's and Production Batch records.
  • Develop and review batch records and log books related to manufacturing and equipment.
  • Drafted and edited primer batch records and submitted change requests to QA.
  • Reviewed and released manufacturing batch records of different API's and intermediates.
  • Review completed batch records and ensure GDP and Quality control is followed.
  • Assembled data from batch records to write interim and final products.
  • Experienced in the format and generation of GMP batch records.
  • Reviewed and analyzed batch records for the manufacturing group.

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47. Uplc

low Demand
Here's how Uplc is used in Scientist jobs:
  • Developed methods for detection of small molecules using UPLC-MS and LC-MS/MS.
  • Experience in Calibration of HPLC, UPLC and Dissolution unit.
  • Validated UPLC method for assay and impurities in tablet.
  • Utilize UPLC for drug concentration analysis in support of the electrophysiology assays to provide more accurate potency estimates.
  • Experienced in Calibration of HPLC, UPLC, Dissolution unit, pH meter, Analytical weight balance and Karl Fischer.
  • Executed multiple tasks such as operated HPLC, UPLC, Dissolution UV vis and Karl Fischer.
  • Developed a QC method for UPLC to analyze a complex mixture of oligonucleotides.
  • Received training on troubleshooting techniques on UPLCs and Empower Software.
  • Use and maintenance of Acquity UPLC instrumentation.
  • Performed comprehensive study on the correlation of preparative instrumentation to ultra-performance liquid chromatography (UPLC) and LC-MS.
  • Trouble shooting of laboratory Shimadzu LC & UPLC systems, AB Sciex 4000/5000/5500/6500 triple quadrupole systems and Thermo Voyager LC-MS.

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48. Sample Preparation

low Demand
Here's how Sample Preparation is used in Scientist jobs:
  • Perform a variety of complex sample preparation and analysis procedures to quantitatively measure pharmaceutical compounds in a variety of biological matrices.
  • Sample preparation for these analyses includes homogenization techniques for various tissues and solid-phase or liquid-liquid extraction in a low-throughput format.
  • Developed and implemented improved sample preparation methods resulting in decreased turn around for data related to marketing claims.
  • Performed combined sample preparation and nucleic acid amplification assays on clinical samples.
  • Performed complex sample preparations and analysis in support of process development.
  • Worked in a level II bio-hazard laboratory to facilitate sample preparation.
  • Participated in validation of automated robotics for sample preparation.
  • Performed sample preparation and extraction for environmental contaminants.
  • Performed both sample preparation and instrument analysis.
  • Conducted analysis of body fluids and tissue samples via protein precipitation, solid-phase extraction, and other automated sample preparation techniques.
  • Sample preparation and extraction of blood, CSF, using protein precipitation, solid phase extraction, liquid-liquid extraction.
  • Performed blood sample preparation and testing as well as routine QC to assess instrument performance against specifications and requirements.
  • Performed sample preparation methods for extraction, separation, and analysis as detailed in the standard operating procedures.
  • Prepare incoming samples for analysis within appropriate holding time using various EPA methods in Organic Sample Preparation Department.
  • Demonstrated expertise in performing sample preparation and analysis for OROS and TMG products (in-process and final).
  • Sample preparation of plasma and tissue in a 96 well plate format by hand and Hamilton robot.
  • Gained significant experience in buffer preparation, antigen coating of assay plates and manual sample preparation.
  • Improved sample preparation processes to reduce repetitive motions when an analyst performs ACI sample preparation.
  • Define and document test cases to validate the performance of sample preparation applications.
  • Streamlined an established LC/MS/MS assay by reducing sample preparation time by 70%.

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49. IR

low Demand
Here's how IR is used in Scientist jobs:
  • Developed an industry-first solution to correct for internal gradient and restricted diffusion effects in NMR interpretation; patent filed.
  • Contributed to the design, process optimization, and implementation of multiple products within a multidisciplinary team environment.
  • Review and provide strategic input into clinical study protocols to determine supply requirements and propose optimal packaging configurations.
  • Organized and facilitated science-focused summer camps for elementary school age children; directly interacted with kids and clients.
  • Supported various site programs such as groundwater monitoring, air monitoring, radioactivity monitoring, and emergency response.
  • Prepared necessary solutions and materials required in the performance of specified tests Recorded and reported data into LIMS accurately
  • Develop proposals and solicit sponsorship in support of research directed at new composite formulations of energetic materials.
  • Screened internal bacterial libraries for candidates with desired characteristics to improve current products and develop new ones.
  • Reported on project development, maintained lab documentation as required for scientific, regulatory and proprietary property.
  • Supported ecological and environmental monitoring programs to meet Millstone Station and other Dominion Nuclear regulatory requirements.
  • Communicated and collaborated with external business partners and internal cross functional groups in the multicultural environment.
  • Performed equipment troubleshooting as required to ensure laboratory equipment performed within optimal tests parameters.
  • Directed external FTE's to ensure timely delivery of desired analogs and intermediates.
  • Supervised up to 6 individual contributor direct report staff including stability technician activities.
  • Collaborate with classroom teacher to increase inquiry based learning opportunities in classroom environment.
  • Responded to customer inquiries, clarified results and performed OOS investigations when necessary.
  • Proposed stability requirements in order to support concurrent clinical support stability studies.
  • Established academic collaboration to acquire knowledge and techniques for exploring target prospective.
  • Managed clean room facility and company-wide equipment inventory, calibration and repair.
  • Optimized techniques and culture conditions to evaluate expression of desired target proteins.

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50. PK

low Demand
Here's how PK is used in Scientist jobs:
  • Conducted analysis on target compounds including their purification, characterization and some PK/PD studies.
  • Performed PK data processing and interpretation; authored experimental reports and technical documents.
  • Designed and executed InVitro DMPK experiments to support early stage exploratory drug projects.
  • Defined PK/PD/efficacy relationships in collaboration with colleagues within DMP.
  • Analyzed results and generate PK parameters using WinNonlin software.
  • Supervised and led a discovery and development DMPK laboratory.
  • Project representative for Discovery DMPK.
  • Demonstrated a case-study for using fisher information content in the PK-PD model to guide optimal sampling of dosage times.
  • Performed general upkeep, maintenance, and calibration of instruments including ICP-MS, AA, and microwave digestion oven.
  • Developed a 1 min ballistic gradient LC-MS/MS method for rapid PK assays which increased sample throughput by 50%.
  • Review Phase III clinical study management reports for PK-related queries and follow up with appropriate personnel to resolve queries.
  • Invented two SQ compounds with excellent potency, PK and safety profile via SAR study, and lead optimization.
  • Participated in chemistry dose solution preparation and formulation, blood sampling, tissue harvest, and ongoing PK/PD studies.
  • Coordinated interactions with other program elements (Johns Hopkins APL, NUWC Newport, ONR, etc.)
  • Drug distribution specialist for DMPK providing all project support for protein binding, plasma stability and blood/plasma partitioning.
  • Provided support for UST remediation activities during Cleveland Hopkins Airport expansion for the City of Cleveland Port Authority.
  • Worked closely with Chemistry, Toxicology, DMPK, Quality, Clinical, and Regulatory Affairs departments.
  • Improved activity and metabolic profile of lead compounds through SAR and under consideration of DMPK data.
  • Summarize and analyze the data using excel and WinNonlin (Phoenix) software for PK/PD modeling.
  • Validated 25+ methods and analyzed 60000+ PK and clinical samples with minimal failures and investigations.

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20 Most Common Skill for a Scientist

Analytical Methods17.1%
Lab Equipment10.3%
Cell Culture9.1%
New Product Development8.3%
Stability Samples6.4%
Hplc6.1%
Protein4.9%
Ms4.6%

Typical Skill-Sets Required For A Scientist

RankSkillPercentage of ResumesPercentage
1
1
Analytical Methods
Analytical Methods
12.8%
12.8%
2
2
Lab Equipment
Lab Equipment
7.7%
7.7%
3
3
Cell Culture
Cell Culture
6.8%
6.8%
4
4
New Product Development
New Product Development
6.2%
6.2%
5
5
Stability Samples
Stability Samples
4.8%
4.8%
6
6
Hplc
Hplc
4.6%
4.6%
7
7
Protein
Protein
3.7%
3.7%
8
8
Ms
Ms
3.4%
3.4%
9
9
Data Analysis
Data Analysis
2.6%
2.6%
10
10
R
R
2.6%
2.6%
11
11
FDA
FDA
2.5%
2.5%
12
12
Elisa
Elisa
2.2%
2.2%
13
13
DNA
DNA
2.1%
2.1%
14
14
GLP
GLP
2.1%
2.1%
15
15
Raw Materials
Raw Materials
2%
2%
16
16
Uv/Vis
Uv/Vis
1.9%
1.9%
17
17
GMP
GMP
1.8%
1.8%
18
18
Synthesis
Synthesis
1.8%
1.8%
19
19
Rt-Pcr
Rt-Pcr
1.7%
1.7%
20
20
Validation Protocols
Validation Protocols
1.6%
1.6%
21
21
GC
GC
1.5%
1.5%
22
22
QC
QC
1.5%
1.5%
23
23
Drug Products
Drug Products
1.4%
1.4%
24
24
Lims
Lims
1.3%
1.3%
25
25
Assay Development
Assay Development
1.2%
1.2%
26
26
LC
LC
0.9%
0.9%
27
27
API
API
0.9%
0.9%
28
28
Technical Reports
Technical Reports
0.9%
0.9%
29
29
Cros
Cros
0.9%
0.9%
30
30
Biology
Biology
0.9%
0.9%
31
31
Drug Discovery
Drug Discovery
0.9%
0.9%
32
32
RNA
RNA
0.9%
0.9%
33
33
Clinical Trials
Clinical Trials
0.8%
0.8%
34
34
QA
QA
0.8%
0.8%
35
35
Flow Cytometry
Flow Cytometry
0.8%
0.8%
36
36
IND
IND
0.7%
0.7%
37
37
Technical Support
Technical Support
0.7%
0.7%
38
38
Ftir
Ftir
0.7%
0.7%
39
39
Data Collection
Data Collection
0.7%
0.7%
40
40
Research Projects
Research Projects
0.7%
0.7%
41
41
ISO
ISO
0.7%
0.7%
42
42
Sds-Page
Sds-Page
0.6%
0.6%
43
43
NMR
NMR
0.6%
0.6%
44
44
DOE
DOE
0.6%
0.6%
45
45
Small Molecules
Small Molecules
0.6%
0.6%
46
46
Batch Records
Batch Records
0.6%
0.6%
47
47
Uplc
Uplc
0.6%
0.6%
48
48
Sample Preparation
Sample Preparation
0.6%
0.6%
49
49
IR
IR
0.5%
0.5%
50
50
PK
PK
0.5%
0.5%

24,724 Scientist Jobs

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