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  • R&D Principal Scientist

    M2 Ingredients 4.5company rating

    Scientist job in Vista, CA

    This is a hybrid position, located in Vista, CA. Unfortunately, we are not able to provide visa sponsorship at this time. About the Company We are passionate about our mission to harness the amazing power of mushrooms for healthier lives. M2 Ingredients is the leading vertically integrated organic functional mushroom solution provider in the Western Hemisphere. We grow our portfolio of functional mushrooms indoors in our controlled, state-of-the-art facility in Vista, CA. M2 Ingredients sells its functional ingredients to global brands in the supplement, beverage and food channels. M2 Ingredients was founded in 2010 by Sandra Carter, a health and wellness expert with a PhD in preventative medicine, and Steve Farrar, a mycologist with over 30 years of experience in growing mushrooms. Both founders are active in the business. Position Summary: The R&D Principal Scientist will lead projects for testing method development & optimization for the M2 Ingredient business. The R&D Principal Scientist will be charged to lead projects related to the improvements of the M2 ingredient portfolio to improve the ingredients potency and bioavailability through strain selection, growth conditions, bioactive compound testing method development and ingredient processing. The R&D Principal Scientist will also participate in the operational readiness to ramp up and launch new ingredients on time, with a high level of quality and maximum customer availability. A successful R&D Principal Scientist is a creative and collaborative partner, is driven, organized, and detail oriented and is thoughtful and effective in problem solving and responding to the customer's needs. Position Responsibilities Collaborate with external labs to optimize and develop analytical methods to strengthen the M2 Ingredients product specifications. Develop and validate through testing the Finish Product Specifications of each new ingredient as it relates to the functional and nutritional benefits of the product. Support the FSQA team in investigation that involves testing method viability and accuracy. Actively participate in new ingredient development, from discovery and initial feasibility assessment to product qualification, business evaluation and commercialization such as new strain development to create ingredient specification that are more competitive in the marketplace. Contribute new ideas within the cross-functional team that drives the innovation pipeline at M2 Ingredients through scientific and technical insights. Ensure projects meet deadlines, quality and regulatory standards from ideation to full scale production by engaging the cross functional team on the project timeline and keeping the team informed and accountable throughout the development phases. Collaborate with CSO and Mycology team on creating patent filing submission dossiers and contribute to patent strategy. Qualifications M.Sc. in chemistry, biochemistry or other relevant science degrees. 5 + years of experience in the functional ingredients, dietary supplements or functional food industry in product development role including experience formulating, leading plant trials and production start-up. Laboratory experience or experience interpreting results for the following analytical methods an asset: mass spectrometry, DNA sequencing, chromatography, antibody assays. Experience managing external laboratories and contract research organization Excellent verbal and written communication skills. Proven ability to prioritize and organize workload to ensure timely delivery of tasks. Passion for product testing, food science and safety and quality in the food industry. Exceptional ability to identify and resolve problems efficiently and effectively by providing appropriate solutions. COMPENSATION & BENEFITS This full-time role will receive a competitive salary + benefits, including medical, dental, vision, PTO, 401k match. This position's anticipated annual pay range is $120,000 - $140,000 plus an annual bonus. Various factors are considered when determining an individual's compensation-including a candidate's professional background, education, certifications, experience, professional licenses, and location. Final offer amounts may vary from the amounts listed. We neither ask for nor consider the salary history of applicants. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law. LOCATION M2 Ingredients is located in Vista, CA (about 35 miles north of San Diego and 60 south of Orange County). This position requires you to work full time, on-site in our Vista, CA location minimum of 3 days per week.
    $120k-140k yearly 5d ago
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  • Associate Scientist

    Planet Pharma 4.1company rating

    Scientist job in San Diego, CA

    Representative responsibilities will include, but not necessarily be limited to, the following: Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays. Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations. Author and review QC analytical SOPs, protocols, and reports as needed Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures. Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated Skills: Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products. Education: BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role Experience in an FDA-regulated environment Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic Excellent organizational and communication skills Experience with JMP statistical software a plus.
    $71k-108k yearly est. 5d ago
  • Process Development Associate

    Mastech Digital 4.7company rating

    Scientist job in San Diego, CA

    • Primarily responsible for commercial manufacturing. Also responsible for the transfer of manufacturing processes from R&D to Manufacturing and continuous improvement of existing processes. Essential Duties and Responsibilities The incumbent may be asked to perform other function-related activities in addition to the below mentioned responsibilities as reasonably required by business needs. • Maintains the Pilot Plant laboratory under cGMP conditions. • Produces development, pilot, and production materials per written instructions. • Completes ERP transactions. • Stocks and maintains the laboratory supplies. • Keeps accurate records and documentation. • Completes laboratory work and associated paperwork by assigned completion dates. • Produces notebook materials per written instructions. • Develops manufacturing processes for transfer to Manufacturing. • Assists with execution of process validation of new and existing manufacturing processes. • Improves manufacturing processes. • Completes cycle counts. • Washes lab ware. Qualifications Education • Bachelor's degree (sciences) Experience • 1+ years' experience preferred Skills • Basic knowledge of QMS (Quality Management System)/GMP requirements Must follow all applicable FDA regulations and ISO requirements.
    $70k-86k yearly est. 4d ago
  • Clinical Laboratory Scientist

    Kelly Science, Engineering, Technology & Telecom

    Scientist job in San Diego, CA

    Senior Clinical Laboratory Scientist Direct Hire San Diego, CA Onsite | Full-Time | Sunday-Thursday, 12:30 PM - 9:00 PM Base pay range: $54-$63/hr Our client, a leading global diagnostics company transforming cancer care, is seeking an experienced Senior Clinical Laboratory Scientist to join their growing team in San Diego. This is an outstanding opportunity for a seasoned CLS professional to contribute to high-impact molecular diagnostics while working in a collaborative, mission-driven environment. As a recruiting partner, we are seeking candidates who thrive in fast-paced, high-complexity clinical laboratory settings and bring strong technical, analytical, and leadership abilities. About the Role The Senior Clinical Laboratory Scientist will independently perform high-complexity clinical testing, support assay quality and instrument performance, and contribute to workflow optimization. This role also supports training, SOP development, assay validation, and cross-functional collaboration across QA, Data Management, Client Services, and Clinical Research. Key Responsibilities Perform high-complexity molecular diagnostic testing in accordance with CLIA, SOPs, and quality management systems. Document all QC activities, maintenance, calibrations, and corrective actions. Troubleshoot routine and complex assay/instrument issues and serve as a subject matter expert. Lead process improvement initiatives, including workflow efficiency, TAT improvements, and cost-saving efforts. Participate in proficiency testing, regulatory inspection readiness, and quality committee initiatives. Support assay validation projects and contribute to development and revision of SOPs. Train and assess competencies of testing personnel and support expansion of laboratory capabilities. Qualifications Active California CLS or CGMBS license (required). Bachelor's degree in a chemical, biological, physical, or clinical lab science (or qualifying equivalent). Minimum 4 years of experience as a CLS in a molecular clinical lab. Experience with high-complexity testing; molecular methods (PCR, microarray, Sanger/NGS) highly preferred. Strong analytical, troubleshooting, and technological skills. Excellent communication, teamwork, and adaptability in a fast-paced lab environment. Ability to maintain required CE units for state licensure. Compensation Final compensation is dependent on experience, skillset, and relevant background. Additional bonus and stock incentives may be available through the client's total rewards program. Why Join This Team? Our client is recognized as a Certified Great Place to Work (2024) and offers exceptional opportunities for growth within an innovative, patient-focused organization. Their work directly impacts cancer diagnostics, empowering clinicians and improving patient outcomes globally.
    $54-63 hourly 3d ago
  • Clinical Lab Scientist, Generalist OR CGMBS

    Proven Recruiting 4.3company rating

    Scientist job in San Diego, CA

    Clinical Lab Scientist (Generalist OR CGMBS),1 year contract (Sun - Thurs 1st Shift) Looking for an exciting CLS role? One of San Diego's leading biotech companies is looking for a competent, reliable CLS to add to their dynamic team. This role offers the opportunity to build upon the foundation you've already laid in your industry experience and refine your clinical testing expertise with high complexity assays. Don't miss this rare opportunity to learn from top professionals, grow into a more senior role, and excel in a challenging and supportive environment. What you will do: Perform molecular genetic testing on clinical specimens using PCR and sequencing (NGS) Reviewing and reporting patient results. Performing quality control and quality assurance activities as needed. Comply with all applicable local, state and federal laboratory, quality, and safety requirements. Who you are: Requires valid California Department of Public Health Clinical Laboratory Scientist (CLS) generalist license OR Clinical Genetic Molecular Biology Scientist (CGMBS) license (no exceptions) 3+ years experience in high complexity clinical laboratory testing, preferably in molecular diagnostics Performance of molecular testing (PCR, Microarray, Sanger/NGS sequencing) a huge plus What does this position pay? Compensation is determined by several factors which may include skillset, experience level, and geographic location. The expected range for this role is $36 to $50 per hour. Please note this range is an estimate and actual pay may vary based on qualifications and experience. Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!
    $36-50 hourly 2d ago
  • Scientist

    Otonomy Inc. 3.8company rating

    Scientist job in San Diego, CA

    Demonstrate expert technical knowledge and practical experience in bioanalytical methods investigating therapeutic targets and candidate molecules for disorders of the ear. Develop, design, conduct and analyze in vivo pharmacokinetic studies of drug candidates and report findings. Work includes bio-analytical methods focusing on small molecules and nucleic acid based pharmaceutical products using LC/MS/MS, qPCR, UV/fluorescence detection methods and other relevant assays. Manage and coordinate interactions with external CROs. Be an active member of the Research and Preclinical Development Team to generate data and reports to support new candidate assessment, IND, NDA and other regulatory filings. Essential Functions: Develop, design, conduct and execute bioanalytical experiments supporting the development of small molecule and nucleic acid-based therapy products. Support preclinical efforts by designing and conducting laboratory studies relating to bioanalytical and pharmacokinetic investigations. Experience with ADME assays (microsome and hepatocyte metabolism, transporters, absorption, protein binding, CYP450 substrate and inhibition assays) a plus. Actively contribute to project and program teams and provide clear and consistent communication of ideas, data, conclusions and outcomes. Stay abreast of the latest techniques and technical knowledge in the bioanalytical arena and share that information with the Research & Preclinical Development team. Serve as technical expert and routinely educate peers and others. Mentor the scientific staff for development of approaches, techniques and best practices. Manage and coordinate interactions with bioanalytical CROs as needed, relating to preclinical and clinical studies. Contribute to manuscripts for key publications (abstracts, posters, presentations) consistent with the overall scientific and medical communications plan. Present data at internal meetings and external scientific conferences and meetings. Support the development of data and other materials for patents and regulatory documentation. Excellent analytical, research and problem solving skills required. A commitment to high-quality research and the execution of research plans in a timely and organized manner. Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to effectively collaborate with colleagues, vendors and partners, who may have different levels of technical knowledge and understanding and to clearly convey status and progress in areas of responsibility both verbally and in writing May train and/or mentor less experienced personnel. May perform other related duties as required and/or assigned. Quality and Safety Responsibilities Must be aware of and consistently achieve required quality and regulatory compliance. In addition, this position must be aware of and follow all safety policies and instructions at all times. Nature and Scope: Interacts on a regular basis with comparable levels of personnel in Research, CMC and Preclinical Development and occasionally with other groups including Regulatory, Clinical Development and senior management. Requires strong communication skills with the ability to clearly convey status and progress in areas of responsibility both verbally and in writing. Requires a strong working knowledge relevant to the applicable field. Job encounters problems of moderate scope and complexity with variations from the norm. The incumbent typically works independently in agreed project areas and in consultation with supervisor on new assignments and/or in areas of broader scope. Errors in work could cause delays and financial loss. Education: B.S. or M.S. in in Bioanalytical Chemistry, Pharmaceutical Sciences, Drug Metabolism or other relevant life science field, or equivalent education and experience. Experience: Minimum of 3-5 years of experience in a comparable role with a biotechnology or pharmaceutical company or a combination of academia and industry required. Comprehensive knowledge of current practices in bioanalytics relating to small molecules and nucleotide nucleic acid-based pharmaceuticals. Ability to manage and execute on multiple and competing priorities is expected. Excellent verbal and written communication skills as well as strong interpersonal skills, including the ability to interact effectively with collaborators, clients, vendors and personnel, who may have different levels of technical knowledge and understanding. Ability to work as a team member are essential. Working Conditions: Works in a laboratory, facilities and/or manufacturing environment. May on a continuous basis walk, bend and lift up to 40 lbs. The noise level in the work environment is usually moderate to high. May intermittently sit at desk for a long period of time to answer telephone and write or use a keyboard to communicate through written means. Must be flexible to work varying schedules and hours as needed. Occasional local travel may be required. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Equal Opportunity Employer/Females/Minorities/Veterans/Disability
    $98k-151k yearly est. Auto-Apply 60d+ ago
  • scientist- II

    Artech Information System 4.8company rating

    Scientist job in San Diego, CA

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • The new Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams. • This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as an Associate Scientist. • The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays. • A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. • Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel. Qualifications A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. Additional Information Sneha Shrivastava Technical Recruiter (Clinical/Scientific) Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: ************ | Fax: ************ Connect with us on - LinkedIn | Facebook | Twitter
    $110k-163k yearly est. 60d+ ago
  • Scientist, Oligonucleotide Chemistry

    6084-Janssen Research & Development Legal Entity

    Scientist job in San Diego, CA

    At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Chemical Research Job Category: Scientific/Technology All Job Posting Locations: San Diego, California, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine We are searching for the best talent for Scientist, Oligonucleotide Chemistry in San Diego, CA. Purpose: RNA Therapeutics and Delivery is embedded in Cell & Genetic Medicines, an organization within Therapeutics Discovery, where we are committed to the development of high-quality drug candidates in the Oligonucleotide Therapeutics space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific knowledge and expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers growth opportunity within a dynamic and science driven organization. You will be responsible for: Perform solid phase synthesis, purification, and analysis of oligonucleotides and bioconjugates in a team environment. Support and trouble-shoot process development efforts for synthesis and characterization of oligonucleotides and their bioconjugates with higher throughput and automation. In collaboration with the team, support oligonucleotide analytical efforts, optimization and design for de-risked, tissue-specific delivery. Collect, document and evaluate experimental data and communicate scientific findings as verbal presentations and written reports. Qualifications/Requirements: Education: Minimum of a B.S./B.A. with a minimum of 2-4 years of experience, performing progressively advanced duties at the Associate Scientist level, or the equivalent training/experience is required. Advanced degree is preferred. Skills/Experience: Required: Hands-on experience with an emphasis on si RNA and/or ASO nucleic acid therapeutics synthesis and development. Experience in si RNA synthesis, purification, and analytical characterization Familiarity with the oligonucleotide delivery and drug discovery process Critical thinking and scientific skills and a demonstrated ability to interpret and clearly communicate data Strong team player with the ability to work effectively in a dynamic, matrixed team environment with diverse views Ability to adapt to changing priorities and timelines Preferred Qualifications: Experience in operating instruments and equipment including MerMade and Dr. Oligo synthesizers, as well as HPLC, LC-MS, and UV/Vis purification and characterization instrumentation. Experience in increasing throughput and automation of oligonucleotide synthesis, characterization and documentation processes. Knowledge and experience with delivery of oligonucleotides using bioconjugation strategies. Knowledge of RNA biology and oligonucleotide screening technologies to facilitate effective team collaboration. The expected pay range for this position is $76,000 to $121,000 The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/ performance year. Bonuses are awarded at the Company's discretion on an individual basis. Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave - 80 hours in a 52-week rolling period10 days Volunteer Leave - 32 hours per calendar year Military Spouse Time-Off - 80 hours per calendar year For additional general information on company benefits, please go to: ********************************************* This job posting is anticipated to close on December 11, 2025. The Company may however extend this time-period, in which case the posting will remain available on *************************** to accept additional applications. The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via *******************/contact-us/careers or contact AskGS to be directed to your accommodation resource. Required Skills: Preferred Skills: Analytical Reasoning, Chemistry, Data Analysis, Data Reporting, Drug Discovery Development, Execution Focus, Innovation, Interdisciplinary Work, Laboratory Experiments, Process Oriented, Quantitative Research, Research Ethics, Research Informatics, Scientific Evaluation, Scientific Research, Technical Writing, Technologically Savvy The anticipated base pay range for this position is : $76,000 to $121,000 Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. *********************************************
    $76k-121k yearly Auto-Apply 26d ago
  • Scientist I

    Lancesoft 4.5company rating

    Scientist job in San Diego, CA

    Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience Responsibilities: The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat Qualifications Minimum Bachelor's degree in a biological science discipline Additional Information College degree or HS Diploma with +5 years biopharmaceutical industry experience
    $99k-134k yearly est. 60d+ ago
  • R&D Scientist

    Kalon Executive Search

    Scientist job in San Diego, CA

    Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************
    $120k-140k yearly 23d ago
  • Gas Chromatography Product Development Scientist

    Teledyne 4.0company rating

    Scientist job in San Diego, CA

    **Be visionary** Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, deepwater oil and gas exploration and production, medical imaging and pharmaceutical research. We are looking for individuals who thrive on making an impact and want the excitement of being on a team that wins. **Job Description** **Job Summary:** TAPI is seeking a highly experienced Scientist, with a proven record of developing Gas Chromatography Instrumentation, to join our Research and Development team. This role will focus on the development of new GC-based instrumentation to support innovation in analytical chemistry and production workflows. The ideal candidate will bring deep expertise in gas chromatography, method development, and instrumentation, along with a strong background in production or R&D environments. **Key Responsibilities** + Lead the design and development of advanced gas chromatography (GC) methods and instrumentation. + Operate, maintain, and troubleshoot GC instruments including FID, DBD, FPD, and PID detectors. + Collaborate with cross-functional teams to support product development and quality assurance. + Perform sample preparation, calibration, and quantitative analysis with high precision. + Document and validate analytical methods in compliance with internal and regulatory standards. + Mentor junior technicians and contribute to technical training initiatives. + Communicate findings clearly through technical reports and presentations. **Minimum Qualifications** Education: Bachelor of Science (B.Sc.) in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field. Experience: Minimum of 10 years of relevant work experience in a R&D or Manufacturing environment. Technical Expertise: - Proficiency in GC method development, validation, and troubleshooting. - Proven experience with GC instruments including FID, DBD, FPD, and PID. - Familiarity with chromatography data systems such as Chromperfect . - Strong understanding of sample preparation, calibration, and quantitative analysis. Soft Skills: - Exceptional analytical thinking and attention to detail. - Excellent written and verbal communication skills. **Preferred Qualifications** + Experience in developing GC technologies for novel applications. + Knowledge of regulatory standards and documentation practices (e.g., cGMP, SOPs). + Ability to work independently and manage multiple projects simultaneously. **Why Join TAPI?** At TAPI, you'll be part of a dynamic team driving innovation in analytical science. We offer competitive compensation, a collaborative work environment, and opportunities for professional growth. **Salary Range:** $113,600.00-$151,400.000 **Pay Transparency** The anticipated salary range listed for this role is only an estimate. Actual compensation for successful candidates is carefully determined based on several factors including, but not limited to, location, education/training, work experience, key skills, and type of position. Teledyne conducts background checks on qualified applicants who receive a conditional offer of employment in accordance with applicable laws, regulations and ordinances. Background checks may include, but are not limited to, education verification, employment history and verification, criminal convictions, Motor Vehicle Report (MVR & driving history), reference check, credit checks/credit history and drug testing. All qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. Teledyne and all of our employees are committed to conducting business with the highest ethical standards. We require all employees to comply with all applicable laws, regulations, rules and regulatory orders. Our reputation for honesty, integrity and high ethics is as important to us as our reputation for making innovative sensing solutions. Teledyne is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic or non-merit based factor made unlawful by federal, state, or local laws. You may not realize it, but Teledyne enables many of the products and services you use every day **.** Teledyne provides enabling technologies to sense, transmit and analyze information for industrial growth markets, including aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, energy, medical imaging and pharmaceutical research.
    $113.6k-151.4k yearly 57d ago
  • Associate Scientist - Assay Development

    Plantible Foods 3.8company rating

    Scientist job in Vista, CA

    How you will contribute: We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company. What you will be working on: Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing. Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes. Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color. Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing. Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research. What you bring to Plantible: B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering. 3 to 5+ years of industry experience in assay development in an industrial environment. Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer. Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes. A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action. Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred. Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills. Excellent verbal and written communication and presentation skills. Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment. Thrive in a fast-paced environment where the primary focus is on simplification and optimization. Choose Plantible Foods Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment. At Plantible we are continually working on our offerings to foster the best team. Check it out! Competitive health and wellness benefits Medical, Dental and Vision Insurance Discretionary Unlimited PTO Program Paid Holidays 401k Program Career Stipend Career development and growth opportunities Working in a rapidly growing, flexible and entrepreneurial environment Team building and company-wide events Financial support with your relocation, if necessary, ensuring a smooth transition Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time. If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!
    $74k-112k yearly est. 60d+ ago
  • Associate Scientist I, Discovery Chemistry (Bioconjugation)

    Arrowhead Pharmaceuticals 4.6company rating

    Scientist job in San Diego, CA

    Job Description Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy
    $60k-80k yearly 8d ago
  • Scientist, Protein Production and Characterization

    Director, Business Development In San Diego, California

    Scientist job in San Diego, CA

    Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI
    $98.5k-140k yearly Auto-Apply 57d ago
  • Scientist, Protein Production and Characterization

    Alivamab Discovery Services

    Scientist job in San Diego, CA

    Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI
    $98.5k-140k yearly Auto-Apply 57d ago
  • Manufacturing Scientist

    Universal Sequencing Technology Corporation

    Scientist job in Carlsbad, CA

    Universal Sequencing Technology, a biotech startup headquartered in Canton, MA (~15 miles southwest of Boston) with a location in Carlsbad, CA, is looking for a highly talented Manufacturing Scientist to join the team, located in Carlsbad, CA.* We are excited to provide novel DNA sequencing technology for the Next Generation Sequencing (NGS) platforms that enables many previously unachievable applications. This position is a unique opportunity to commercialize a novel NGS library technology, TELL-Seq TM , an ultra-low input single tube linked read technology which enables many previously unachievable long read applications and to develop disruptive single cell applications. The incumbent will have hands on experience on DNA conjugation and amplification, in-process quality control assay development, filling and labeling experience and capability to increase scalability using technology, equipment, manpower, etc… to meet increasing demand. S/He will work closely with R&D and manufacturing teams to scale up production procedure and accelerate product commercialization. S/He must have excellent documentation skills and strong interpersonal skills, be driven by making high quality products, and enjoy working in a multi-disciplinary environment. Key Responsibilities Engineer scale up procedures for bulk production, filling process and kit assembly Optimize reagent formulation and process for bulk DNA amplification in emulsions Develop in-process quality control assays (analytical) for reagent formulations, productions, characterization and identification Execute well thought out experiments, record results accurately along with in-depth analysis and reports that will be reviewed, approved and filed in QA Create/update manufacturing production protocols, execute protocol and/or train others to do the same Work with other manufacturing personnel to make bulks, fill reagents and assemble kits. This is a hands on, in the lab position Work with Inventory Management to ensure proper handling, storage, usage and accountability of all materials needed to produce or test products Manage and execute stability sampling, storage and testing Manage tasks, projects and timeline to meet deliverable on time and on quality. Manage resources accordingly for the same Write, review and revise SOP's through a Document Change Order. Initiates, Investigates and write up non-conformance reports. Required Skills and Background M.Sc. or Ph.D. in chemistry, chemical engineering, molecular biology, biochemistry, biology, biotechnology or a similar field (B.S. with exceptional experience WILL be considered) Prior GMP and GDP experience is required. Hands on experience with magnetic beads (suspension material), oligo conjugation and quantification Direct experience in nucleic acid amplification technologies, particularly in emulsion PCR Experience in Lean Six Sigma project implementation is a plus 5-7 years experience in a reagent GMP environment Detail oriented and very good documentation skill Hands on leaders perform well in this environment
    $79k-118k yearly est. Auto-Apply 60d+ ago
  • Scientist, Oncology

    Torrey Pines Solutions 4.4company rating

    Scientist job in San Diego, CA

    The successful candidate will have extensive hands-on experience in mammalian cell culture techniques, cell biology, and molecular biology assays. This position will be responsible for supporting efforts towards the development of combination therapies and studying its mechanism of action in various cellular models. This position will report to the Senior Scientist and will be a critical player in the group. ESSENTIAL JOB FUNCTIONS: · Design, execute, and analyze/interpret experiments to advance mechanism of action studies, develop patient responder hypotheses, elucidate mechanisms of resistance and identify rational drug combinations that can be translated to the clinic. · Develop assays to support biomarker selection and identification strategies to be incorporated into developmental programs. · Utilize broad technical expertise in cell biology, tumor cell biology, immune cell biology, and in vivo animal models to design in vitro, in vivo, and ex vivo experiments to expand understanding of our therapeutics. · Document experimental results and present them regularly at group meetings. · Contribute to lab operations as required. JOB REQUIREMENTS: · Ph.D. in Biology with 0-2 years of experience in the field of oncology · Experience in performing drug combination studies and characterizing cancer signaling pathways. · Experience in genetic manipulation of cells via CRISPR and viral transduction, running cellular (2D and 3D viability, apoptotic, cell cycle), molecular and biochemical (q-PCR, western blot, ELISA, Jess) assays. · Experience in target validation, functional and biomarker cell-based assay development. · Proficient in cell biology including sh RNA and CRISPR technologies. · Experience in epigenetic profiling studies (DNA methylation, RNA-sequencing, ChIP-sequencing and ATAC-sequencing) and strong knowledge in enhancer-mediated regulation of the genome is a plus. · Have deep understanding of cancer signaling pathways as evidenced by peer-reviewed publications. · Ability to execute and troubleshoot experiments independently. · Able to analyze, interpret and present data effectively. · Able to adapt quickly to changing needs of the company and work collaboratively. · Deliver results under tight deadlines. · Highly motivated, innovative and strong team player. Excellent time management and organizational skills.
    $83k-131k yearly est. 60d+ ago
  • Research Biologist

    Global Channel Management

    Scientist job in San Diego, CA

    Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Research Biologist requires: Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Experience in running biochemical and immunological assays. Highly motivated and agile biochemist Research Biologist duties: Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies Perform basic tasks to support tissue culture and maintenance of immune competent cell lines Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.) Work with a cross-disciplinary team for data analysis Independently execute experiments, analyze, interpret and present experimental data
    $61k-93k yearly est. 60d+ ago
  • Food Technologist

    M2 Ingredients 4.5company rating

    Scientist job in Vista, CA

    This is a full-time, on-site position in our Vista, CA office. Unfortunately, we are not able to offer visa sponsorship at this time. At M2 Ingredients, we're passionate about our mission to harness the amazing power of mushrooms for healthier lives. We are the leading vertically integrated organic functional mushroom solution provider in the Western Hemisphere. From spore to solution, we grow our portfolio of functional mushrooms in a state-of-the-art indoor facility in Vista, California-ensuring consistency, purity, and quality at every stage. Since 2010, we've partnered with some of the most innovative global brands in the supplement, beverage, and food industries, providing functional mushroom ingredients that deliver real results. Our founders-Dr. Sandra Carter, a health and wellness expert with a PhD in preventative medicine, and Steve Farrar, a mycologist with over 30 years of cultivation experience-remain actively involved in the business and continue to shape the future of functional wellness. Join us and be part of a team that's redefining how the world experiences mushrooms-backed by science, driven by purpose, and committed to quality. Position Summary The Food Technologist will work closely with the M2 Ingredients Sales Team and New Product Development Team to create and validate novel functional mushroom ingredient products. This role requires a hands-on, solutions-focused scientist who is both creative and technically strong. The ideal candidate is passionate about innovation, thinks abstractly, and enjoys solving complex formulation challenges across a variety of product categories. The Food Technologist will perform duties in accordance with industry specific regulations, Global Food Safety Initiative Standards, Hazard Analysis and Critical Control Points Certification, Good Manufacturing Practices, Standard Operating Procedures, Quality Standards, performance expectations as well as Workplace Health and Safety Policies and Procedures. The Food Technologist plays a key role in supporting changes and improvements in performance, food safety and quality. Partnering with Scientific Affairs and cross functional fields, the Food Scientist will support overall food safety and quality culture ensuring Safe & Quality Products. Essential Duties and Responsibilities Collaborate with M2 Ingredient's new product development team and external processors to develop innovative functional mushroom ingredients Develop and deliver high-quality product prototypes to support strategic sales opportunities and customer sampling requests Design and execute experiments to validate functionality and stability of mushroom materials in various finished product applications Maintain detailed formulation records and experimental data, including version control and compliance with regulatory standards Present formulation outcomes and recommendations to internal scientific and cross-functional teams Collaborate with external co-manufacturers and suppliers to support commercialization projects Source ingredients, manage sample inventory, and document all formulations and testing outcomes Qualifications Bachelor's degree (BSc) in Food Science, Biology, Biochemistry, or a related scientific discipline 3-5 years of hands-on formulation experience in food, beverage, or natural supplements Demonstrated experience with a variety of formats such as ready-to-drink (RTD), ready-to-mix (RTM), bars, confections, and cosmetics/personal care Experience managing relationships with external manufacturers or development partners Strong knowledge of food safety standards and regulatory frameworks (e.g., FDA cGMP, HACCP, BRCGS) Excellent communication skills with the ability to explain scientific concepts clearly to technical and non-technical audiences High attention to detail, strong organizational skills, and ability to manage multiple projects in a fast-paced environment Experience with commercial extraction processes is a plus Experience with enzymatic digestion is a plus Why You'll Love Working Here We believe our people are our greatest ingredient, and we're proud to offer a benefits package that supports your health, your life, and your future. When you join M2 Ingredients, you're joining a company that invests in you. Here's what you can expect: Generous Paid Time Off (PTO) and Sick Leave Comprehensive Medical, Dental & Vision Insurance Health Savings Account (HSA) Paid Parental/ Maternity Leave Long-Term Disability Coverage Company-Paid Life and AD&D Insurance Voluntary Life Insurance Options Employee Assistance Program (EAP) 401(k) with Company Contribution At M2 Ingredients, wellness isn't just something we create-it's something we live. COMPENSATION & BENEFITS This full-time role will receive a competitive salary + benefits, including medical, dental, vision, PTO, 401k match. This position's anticipated annual pay range is $85,000 to $105,000 plus a 10% bonus. Equity incentives also will be considered. Various factors are considered when determining an individual's compensation-including a candidate's professional background, education, certifications, experience, professional licenses, and location. Final offer amounts may vary from the amounts listed. We neither ask for nor consider the salary history of applicants. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.
    $85k-105k yearly 5d ago
  • Associate Scientist I, Discovery Chemistry (Bioconjugation)

    Arrowhead Pharmaceuticals 4.6company rating

    Scientist job in San Diego, CA

    Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy
    $60k-80k yearly Auto-Apply 8d ago

Learn more about scientist jobs

How much does a scientist earn in La Mesa, CA?

The average scientist in La Mesa, CA earns between $76,000 and $182,000 annually. This compares to the national average scientist range of $67,000 to $140,000.

Average scientist salary in La Mesa, CA

$118,000

What are the biggest employers of Scientists in La Mesa, CA?

The biggest employers of Scientists in La Mesa, CA are:
  1. WuXi Apptec
  2. Bristol-Myers Squibb
  3. General Atomics
  4. Integrated Resources
  5. Google via Artech Information Systems
  6. LanceSoft
  7. Millennium Health
  8. MillenniumSoft
  9. General Atomics and Affiliated Companies
  10. Pioneer Data
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