Machine Learning Scientist
Scientist job in Cambridge, MA
Machine Learning Scientist - LLM Systems for Scientific Discovery
About the Team
Join the internal AI initiative of a prominent venture studio that has launched 100+ life sciences companies (including Moderna). You'll be part of a ~20-person technical team in Cambridge building advanced LLM and ML systems that accelerate scientific breakthroughs and help launch new AI-first ventures.
What Will I Be Doing:
Research & prototype novel LLM workflows (agents, reasoning systems, tool-use frameworks) tailored to scientific applications
Define success metrics and design custom benchmarks to evaluate AI systems across diverse scientific domains
Collaborate with ML engineers to scale promising prototypes into production systems
Stay at the frontier by synthesizing state-of-the-art research and validating findings through rigorous experimentation
Build feedback loops that incorporate user testing into system development
What We're Looking For:
PhD in machine learning, computer science, statistics, physics, mathematics, or related quantitative field
Research excellence in LLMs or adjacent areas (reasoning/agents, sequence modeling, representation learning, optimization) demonstrated through publications at top venues or impactful work
Hands-on ML experience with PyTorch or JAX, including reproducible experiment workflows
Strong Python skills and fluency with standard ML tools
Ability to work independently while collaborating effectively in a small team
Experience building LLM systems: agentic frameworks, RAG, multi-agent simulations, RLHF/DPO, or evaluation methodologies
Domain knowledge in chemistry, biology, physics, materials science, or related fields
What's in it for me:
Competitive Compensation: $140k-$240k dependent on experience
Work on originating and fostering breakthrough ventures transforming human health and sustainability
Relocation assistance available (typically $10k sign-on bonus)
Apply now for immediate consideration!
Senior Scientist
Scientist job in Lexington, MA
QUALIFICATIONS:
• Bachelor's Degree within subject matter expertise required.
• 18+ years' relevant experience required, or a master's degree with 12+ years' relevant experience, or a Doctoral degree with 6+ years' post-doctoral and/or industry-relevant experience can be considered.
• Relevant required experience includes: Excellent understanding of ADME principles with knowledge of PK/PD modeling or biotransformation, highly desirable
• Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced models
• Demonstrates excellent verbal and written communication skills.
TOP SKILLS PER MGR:
1. Project-facing role (3+ years)
2. ADME or PKPD subject matter expert
ESSENTIAL FUNCTIONS:
• Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals
• Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
• Troubleshoot highly complex tasks through independent and team-based efforts
• Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
• Make independent decisions related to day-to-day experimental activities
• Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
• Analyze complex data with a high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
• Ensure proper documentation of all experiments and data
• Collaborative teamwork
• Communicate regularly with international colleagues within the Client
• Actively participate in cross-functional teams and meetings to drive project success
• Achieve business goals, share learnings, knowledge, and skills & promote cross-functional teamwork
• Share knowledge & expertise to expand team capabilities and goals
• Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
• Write and review collaborative research manuscripts, project documents, and milestone documents
• Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
• Represent the organization as NN-subject matter expert by attending and presenting at scientific conferences and global meetings
Senior DMPK Scientist
Scientist job in Lexington, MA
Job Title: Principal Research Scientist VI
Pay rate: $120-140/hr on w2
Duration: 12 Months (possible opportunity to convert to perm after contract term)
About the Role
We are seeking an experienced DMPK Project Representative to provide scientific leadership in the discovery and optimization of small-molecule drug candidates. This role leads DMPK strategy across multiple therapeutic areas and collaborates closely with cross-functional scientific teams.
The ideal candidate is an ADME or PK/PD subject matter expert with a strong project-facing background and a track record of impactful scientific contributions.
Top Skills
3+ years in a project-facing scientific leadership role
Expertise in ADME and/or PK/PD modeling
Strong publication/abstract history in metabolism, drug interactions, or PK/PD modeling
Key Responsibilities
Serve as the DMPK representative on global, cross-functional small-molecule project teams
Provide expert guidance on experimental strategy, data interpretation, and DMPK strategy
Lead internal and external research efforts supporting drug discovery
Work closely with pharmacology, medicinal chemistry, and CRO teams
Design, troubleshoot, and interpret complex DMPK experiments (in vitro, in vivo, in silico)
Analyze sophisticated datasets and communicate findings to project stakeholders
Ensure accurate documentation and contribute to scientific reports, manuscripts, and milestone documents
Build collaborations with external scientific partners
Represent the organization as a subject matter expert at scientific conferences
Qualifications
Bachelor's degree with 18+ years experience,
OR Master's degree with 12+ years,
OR Doctoral degree with 6+ years relevant post-doc/industry experience
Deep understanding of ADME principles; PK/PD modeling or biotransformation experience preferred
Experience working with outsourced or hybrid ADME models is a plus
Strong communication skills-verbal, written, and cross-functional
Ideal Candidate
You thrive in a scientifically complex, highly collaborative environment and enjoy integrating DMPK strategy to advance drug discovery programs. You're comfortable leading projects, influencing cross-functional teams, and representing DMPK expertise internally and externally.
Senior Assay Development Scientist/Engineer
Scientist job in Burlington, MA
+++
SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker.
We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing.
+++ The Opportunity +++
We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today.
This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels.
+++ What You'll Do +++
Core Assay Development
Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform.
Design, execute, and interpret experiments focused on:
Binding kinetics & equilibrium optimization
Surface functionalization strategies
Competitive assay dynamic-range shaping
Calibrator and control development (matrix selection, commutability)
Assay precision, stability, robustness
Analytical Performance & Validation
Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17).
Establish and demonstrate performance for:
Analytical sensitivity & functional limit (LoB/LoD/LoQ)
Linearity & reportable range (including hook effects, competitive assay inflection characterization)
Repeatability, reproducibility, and nested CV analysis
Interference and cross-reactivity studies
Matrix equivalency & recovery studies
Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks).
Cross-Functional Integration
Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance.
Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing.
Documentation & Execution
Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations.
Present results across the company to inform design decisions and product milestones.
+++ What We're Looking For +++
Technical Background
PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields.
Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus.
Demonstrated ability to independently solve complex analytical and biochemical problems.
Hands-on experience with complex analytical workflows, assay automation, and instrumentation.
Strong understanding of calibration design, commutability, and control strategies.
Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks.
Regulatory & Platform Experience (Bonus)
Experience with IVD development, ISO 13485, or 21 CFR 820.
Experience with POC or novel-platform assay development.
Knowledge of label-free sensors, waveguides, or photonic resonance systems.
Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation.
Personal Traits
Strong scientific intuition paired with rigorous data discipline.
Thrives in a fast-paced, milestone-driven startup environment.
Creative problem solver willing to challenge established assay paradigms.
High integrity, willingness to own outcomes, and a collaborative mindset.
+++ Why This Role Is Unique +++
Most assay developers spend their careers optimizing assays on platforms that already exist.
At SiPhox, you will:
Build the first generation of photonic immunoassays deployed in consumer health.
Design assays whose constraints are shaped by semiconductor physics as much as biochemistry.
Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins.
See your work ship in a product used at home by real people, not just research labs.
If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
Senior Food Scientist
Scientist job in Ayer, MA
MUST HAVES:
Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred; PhD or PharmD a plus).
5+ years of product development experience from concept to commercialization in nutrition, food, beverage, supplement, nutraceutical, or biotech industries.
Previous experience in basic and applied research and development preferably in small/mid-sized nutrition, food, beverage and/or biotech company.
Strong background in food science, ingredient interactions, and process impact on nutrient stability.
Knowledge of food safety standards and aseptic processing
Electrochemist -- GOEDC5653014
Scientist job in Marlborough, MA
Prepare chemical solutions and maintain plating baths for electroplating operations.
Operate and maintain electroplating equipment including tanks, rectifiers, and agitation systems.
Calibrate and maintain laboratory instruments such as pH meters, spectrophotometers, and conductivity meters.
Perform routine and specialized tests to monitor plating thickness, adhesion, and surface finish properties.
Analyze chemical concentrations and adjust bath compositions to maintain optimal plating conditions.
Document experimental procedures, results, and observations in lab notebooks and digital systems.
Clearly and concisely communicate research to team lead and other team members.
Collaborate with R&D teams to assist in research and development of new plating processes and surface treatments
Collaborate with sales teams to troubleshoot customer plating issues.
Ensure compliance with safety protocols, environmental regulations, and waste disposal procedures.
Preferred:
Experience with production-scale electroplating.
Associate, Bachelor, or Master's degree in Chemistry, Chemical Engineering, Materials Science, or related field.
1+ years of experience in a chemical laboratory setting, with a focus on electroplating or surface finishing is a plus
Strong understanding of electrochemical principles and electroplating chemistry (e.g., nickel, copper, silver, tin) is a plus
Experience with a diverse range of analytical equipment, including UV-Vis, AA, SEM, XRF, XRD, wet chemical techniques, and surface analysis methods.
Knowledge of ASTM and ISO standards and quality control procedures.
Experience with corrosion science or surface science.
Experience with Lean Six Sigma or certification.
Qualifications:
Strong bias for action and willing to go the extra mile
Well-organized, detail-oriented, and results-driven team player.
Methodical, proficient in data analysis, and excellent problem-solving skills.
Ability to work both independently and as part of a multidisciplinary team.
Familiarity with lab safety standards and chemical handling procedures
Machine Learning Scientist, AI Explainability
Scientist job in Woburn, MA
About Us:
SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones.
To learn more about us, please visit: **********
What We Offer:
A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company.
The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact.
Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology.
Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering.
Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions.
What we Need:
The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology.
Harness internal expertise and collaborate with external research labs to advance scientific ML.
Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery.
This position can be remote.
Essential Duties and Responsibilities:
Research & Development
Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery.
Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference.
Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions.
Model Optimization & Implementation
Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency.
Implement innovative solutions to enhance model performance and scalability.
Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology.
Collaboration & Communication
Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences.
Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently.
The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members.
Education and/or Experience:
MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience.
Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models.
Proficiency in programming languages relevant to machine learning, with a strong preference for Python.
Experience with deep learning frameworks such as PyTorch or TensorFlow.
Proficiency in utilizing causal graphs for AI research and application.
A solid track record of innovative research, preferably with published work in relevant areas.
Excellent problem-solving abilities and a passion for tackling complex technical challenges.
Preferred Qualifications:
Experience with AI applications in material science or battery technology.
Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.
Auto-ApplyScientist I
Scientist job in Salem, NH
Job DescriptionSalary:
The Scientist will contribute to Extractables & Leachables studies performed in the E&L laboratory at Boston Analytical to support client submissions. The ideal candidate will have experience operating LC-MS and GC-MS systems for analysis of volatile, semi-volatile, and nonvolatile organic extractables and leachables samples.
PRIMARY DUTIES AND RESPONSIBILITIES
Prepares extractions for analysis.
Analysis of sample extract solutions by GC-MS and LC-MS to adequately resolve and identify
all compounds.
Coordinate findings with the team to generate conclusions.
Author detailed cGMP report sections for work performed outlining study findings.
Develop analysis methods for drug product leachables testing.
Performs system maintenance and calibrations to ensure equipment is operating with
specified requirements. Ensures all work performed strictly adheres to Company, client and
Pharmacopial requirements.
Proper handling of hazardous waste in compliance with the Company and DES hazardous
waste rules.
REQUIREMENTS & QUALIFICATIONS
Qualification includes a Ph.D. in Analytical Chemistry with 2+ years experience or a Masters
degree and 4+ years experience or a Bachelors with 6+ years of experience performing and
interpreting MS analysis. Knowledge of current Extractable & Leachables guidance (USP, ISO
10993) and best practices preferred. Experience working in a cGMP environment required.
MINIMUM SKILLS REQUIREMENTS
Must have the ability and skill to perform the detailed job requirements noted above
competently, safely and proficiently.
A self-starter, motivated person who possesses good interpersonal skills capable of
effectively interacting with all departments and client personnel.
Must have excellent organizational, verbal communication and technical writing skills.
Must be a team player with integrity and concern for the quality of Company products,
services and staff members.
Demonstrated LC-MS and/or GC-MS operation and data interpretation capability.
Ability to develop and optimize HPLC, UPLC, and GC methods.
Documented success managing complex projects to completion within customer
expectations for deadline, cost, and overall deliverable
Product Development Scientist
Scientist job in Ayer, MA
About Us
Eat Well, Live Well. At Ajinomoto Cambrooke, we build careers grounded in helping improve people's health through nutritional therapies.
Ajinomoto Cambrooke (ACI) was founded by parents looking to develop better solutions for their children with PKU. Over the subsequent 25 years, we have expanded into additional therapeutic areas with a focus on enjoyable nutrition as a core part of normalizing the life for people living with medical conditions.
Joining ACI means becoming part of a diverse team of talented people who want to build their careers while contributing back to society in a positive way. We seek individuals who bring an entrepreneurial mindset with a bias for action and finding solutions. We provide an environment based in mutual respect and collaboration to support you and give you opportunities to learn and develop.
Join us to find a rewarding work experience that lets you be at your best and have an impact on our patient communities.
Why Join Us
Our people are the key ingredient to our success. We offer a collaborative, innovative environment where you can grow your career and make an impact on global food and health solutions.
We provide a comprehensive and competitive total rewards package, including:
• Competitive Pay and Annual Bonus Opportunity
• 401(k) with Company Contributions
• Medical, Dental, and Vision - Effective Day 1
• Paid Time Off, Company Holidays, and Floating Holidays
• Paid Parental Leave
• Wellness Programs and Yearly Wellness Reimbursement
• Work Flexibility
• Company-Paid Life and Disability Insurance
• Employee Assistance Program (EAP)
• Tuition Reimbursement Opportunities
• Career Growth and Development within a Global Organization
• Company-Provided Mental Health and Caregiving support
Overview
The Product Development Team supports the medical nutrition business by developing new and revising existing product formulations to meet target characteristics that will deliver positive patient outcomes through therapeutic nutrition. Strong collaboration with the Directors of Medical Nutrition, Marketing, and Sales will be required to ensure desired nutritional levels are achieved throughout the product shelf-life, patient insights on flavor, texture, and palatability are incorporated. In this role, you will contribute to the ideation and exploration for uses of new to ACI ingredients and new to ACI business ventures in additional disease-states reliant on specialized medical nutrition. This position sits in our Corporate Office located in Ayer, MA.
Qualifications
EDUCATION, CERTIFICATIONS AND EXPERIENCE:
• Minimum bachelor's in food science, nutrition, or related field; Master's degree preferred. PhD, PharmD a plus.
• 5+ years of experience in product development, with ability to take concepts from bench top to commercialization for nutritional beverages and / or nutritional powder blends from concept to commercialization.
• 5+ years in basic and applied research and development preferably in small/mid-sized nutrition, food and/or biotech company. Experience with food/beverage formulation and manufacture of nutritional products that meet stability, sensory and nutritional requirements. Direct experience with aseptic processing / Tetra Pak a plus.
• Expert scientific knowledge in food science with emphasis on product development involving interaction amongst ingredients and impact of process techniques on use of micro-nutrients.
• Experience with nutritional modeling software and familiarity with FDA regulations preferred, exposure to EU regulations a plus.
• Able to design and monitor product shelf-life procedures both regular and accelerated for nutritional products.
• Strong translational science background with experience in converting basic nutrition-science insights into consumable products.
KNOWLEDGE, SKILLS AND ABILITIES:
• Build relationships with vendors to source ingredients to meet product specifications.
• Overall understanding of how business units interact to facilitate successful product development and commercialization.
• Ability to define new product needs in terms of process needs and product characteristics including organoleptic needs / claims
• Demonstrated Leadership capability with a focus on innovation to drive product development proactively and passionately.
• Exhibit the understanding of use of standard operation procedures related to product development, process development and product shelf-life determination.
• Well versed with food safety requirements and regulations.
• An understanding of human nutrition and ability to review primary scientific literature.
• A strong ability to communicate basic science and technical challenges to non-technical audiences.
• A strong understanding of ingredient interactions in a food/beverage matrix throughout processing and shelf life.
• Ability to design shelf-life evaluation matrices considering product composition, process impact and other critical factors when designing new products in medical nutrition arena.
• An understanding of macro and micro-nutrient analytical procedures and their principles.
• Ability to work in a fast paced, cross functional team environment.
• Excellent analytical skills, strong attention to details, good communication and interpersonal skills.
• Excellent organizational skills, the ability to balance multiple projects, set priorities, and drive results.
Working Conditions / Physical Requirements
WORKING CONDITIONS:
This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. as required
PHYSICAL REQUIREMENTS:
Position requires the ability to occasionally lift up to 50 pounds, stand, walk, bend, reach, push, and pull.
Ability to use a computer, keyboard, telephone, and other office equipment.
Ability to wear all required PPE.
Responsibilities
• Utilize your exemplary food science and ingredient know-how to co-create and execute medical formula products against ACI's strategic R&D roadmap to support the overall corporate strategy while meeting the internal quality expectations.
• Support the Leadership and Management teams with scientific support in the areas of product development, clinical development, product manufacturing and new ingredient compound / product initiatives.
• Research and help develop clinical evidence supporting existing and new products and ingredient compounds for use in commercial activities.
• Participate in conferences, clinician meetings and other forums to present ACI's clinical evidence.
• Ensure existing and new products, processes or ingredient compounds have strong Intellectual Property protection thus providing ACI a sustained competitive advantage.
• Other duties as assigned.
Salary Range $105,000 - $130,000 Annual with potential 12.5% Bonus EEO Statement
Ajinomoto Cambrooke, Inc. is an Equal Opportunity Employer-Vets/Disabled, committed to a diverse workforce. If you need assistance with completion of an application for employment, please contact Human Resources Department at ************.
Auto-ApplyResearch Scientist II, Cancer Cell Model Development and Resistance Project
Scientist job in Cambridge, MA
General information Location Cambridge, MA Ref # 43395 Job Family Research Date published 12/09/2025 Time Type Full time Pay Range 100,000 - 140,000 Usd Annual Description & Requirements The Broad Institute of MIT and Harvard is the world's leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. We seek to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.
We are seeking a highly motivated and innovative scientist to lead collaborative initiatives in partnership with the Cancer Dependency Map and Cancer Cell Line Factory programs and the Sellers and Getz labs at the Broad Institute. The primary goal of this role is to develop advanced laboratory cellular models to enable functional genomics, drug screening, and drug resistance studies. Our current focus is on deriving 3D models for pediatric and rare cancers, with an initial pilot to generate cancer-resistant cell lines for major oncology drugs. This work will lay the foundation for expanding cancer cell line diversity through additional grant funding and external collaborations. The ideal candidate will be a proactive, curious scientist with a strong background in cell biology, patient-derived cancer models, drug resistance research, and platform development. This position also offers the opportunity to build leadership skills while working closely with Senior Group Leaders.
Qualified candidates should have:
A Ph.D.in a biological science (such as cell biology, biochemistry, cancer biology, or a related field) and a completed or soon-to-be-completed postdoctoral fellowship in a similar field.
2+ years of experience as a postdoc or in the industry.
Excellent organizational and time management skills with strong attention to detail.
Experience in cell biology with a focus on method development, team management, and mentoring junior research associates is highly desirable.
Required Skills:
Self-motivated and curious, with the ability to lead scientific research effectively.
Demonstrated excellent problem-solving and communication skills with leadership, colleagues, and junior research associates.
Track record of independently delivering scientific results.
Expertise in molecular and cell biology techniques, including flow cytometry, immunofluorescence staining, Western blotting, ELISA, HTS cell culturing, 3D cell culturing, drug testing, etc.
Impeccable and efficient experimental design, assay development, and execution.
Strong commitment to "leading from the bench".
Excellent interpersonal, written, and oral communication skills, perform detailed data analysis, and accurate record-keeping to support the cell model team members.
Extensive experience in following and improving assay protocols is preferred.
Responsibilities:
Lead experimental design for cell model development, implement newly developed protocols, and conduct proof-of-concept studies to evaluate feasibility and optimize workflows.
Serve as the technical lead and subject matter expert for cell model development efforts, driving strategic improvements to enhance efficiency, success rates, and overall platform capabilities.
Validate cell models through sequencing technologies and oversee model fidelity assessments using flow cytometry, immunofluorescence, western blotting, and other relevant assays in collaboration with internal Scientists and Research Associates.
Lead drug resistance modeling projects to establish oncology drug-resistant clones for functional genomics analyses.
Manage and mentor Research Associates, fostering scientific and professional growth while ensuring high-quality data generation.
Collaborate with Sellers Lab, Getz Lab, Cancer Dependency Map, PRISM drug screening, Cancer Genomics, and Cancer Data Sciences teams to advance research initiatives and share expertise.
Coordinate closely with cancer genomics core staff to integrate experimental data with genomic insights for comprehensive analysis and interpretation.
Identify opportunities for platform innovation and expansion to address emerging scientific needs and challenges.
Partner with internal teams on large-molecule discovery and validation efforts to support broader oncology research goals.
The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact ***************************** for assistance.
Scientist - Process Research & Development
Scientist job in Devens, MA
Who We Are:
At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented and diverse workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference.
Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation.
Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients.
Role Overview:
The Scientist I - Process Research & Development (PRD) is responsible for conducting small to large scale chemical reactions to optimize synthetic routes of active pharmaceutical ingredients (APIs) under the direction of project technical leads to deliver projects on target with quantity, quality, time, and within budget.
Core Responsibilities:
Delivers experimental output with a high scientific integrity, both on time and target, and of high quality with guidance.
Exhibits safety awareness, safely conducts lab and other operations and hold themselves accountable for safe behavior in the work environment.
Maintains technical equipment and services.
Acts on feedback and show continuous commitment to learning and development.
Lead technical and operational areas and support troubleshooting for complex scientific issues under minimal guidance.
Expertly shares knowledge, skills and experience, communicating internally and externally. May lead focused projects as key contact.
Keeps accurate, legible and complete records of all experiments, observations, and equipment.
Writes high quality reports and delivers presentations to customers and management with some guidance in alignment with project milestones.
Contributes to sustaining good customer relations and identifies new commercial opportunities.
Actively contributes to the technical development of the department and company.
Accomplishes additional duties within the employee's skills and abilities per reasonable request.
Qualifications:
PhD degree (or equivalent experience) in a chemistry related discipline.
2+ years hand on experience with PhD; 5+ years hand-on experience if Master's degree.
Proficiency with relevant lab and analytical techniques.
Previous industry experience in relevant areas.
Proficiency with relevant analytical techniques within an industry environment.
Ability to write clear and concise technical reports.
Good understanding of Microsoft Office and other relevant technical software platforms
Skilled in written and spoken communication and proven ability to effectively interact with management.
Demonstrates good judgment, quick decision-making skills, and the ability to work independently and in a team environment.
Physical Demands & Work Environment:
Stand, walk, and manually operate objects, tools, or controls; reach with hands or arms; climb, balance, stoop, kneel, or crouch when necessary for the job activity.
Lift and/or move up to 50 pounds.
Specific vision abilities include near, distance, peripheral, color perception, and the ability to adjust focus.
Regularly work with moving mechanical parts and may work with toxic or caustic chemicals.
The work may be performed in humid areas with low or high temperatures.
This work may need to work with a respirator or operate with full-body Tyvek suits and supplied air or PAPR.
Our Commitment:
Health & Wellness: Comprehensive health & Wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies.
Financial Wellness: Comprehensive total compensation package that includes competitive base salary, Defined Contribution Pension program, eligibility for performance-based bonuses, and attractive 401(k) Plan with company match.
Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs.
Inclusive Culture: At Veranova an inclusive culture is integral to our values. We are committed to ensuring that everyone can bring their full self to work and thrive in their career.
How to Apply:
At Veranova, we are on a mission to meet people that believe in our values and can contribute to the team in a variety of ways. Please visit **************** to view all open roles and join our Talent Community to stay connected and learn about opportunities as they arise.
We value a range of experiences and perspectives. If you want to be part of improving and saving the lives of patients, we encourage you to apply regardless of whether you meet every qualification listed.
If you are a veteran, first responder, or in the process of transitioning from service member to civilian life, we encourage you to apply. Your experience brings invaluable skills and insights that can contribute to our team.
For applicants who may require a reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email to ****************************** in order to confirm your request for an accommodation. Please include the job number, title, and location of role. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Veranova employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.
Additional Information:
Applicants for this role must be authorized to work in the United States without further employer sponsorship.
Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting.
Important Notice Regarding Recruitment Scams: Veranova is committed to providing a professional and secure recruitment experience for all applicants. Unfortunately, fraudulent job postings and recruitment scams are becoming more prevalent. We want to ensure that all candidates are aware of potential scams. Please see our notice here.
Legitimate communications from Veranova will only come from official email addresses using our domain: @veranova.com.
Legitimate LinkedIn communications will only come from active Veranova employees.
Veranova will never ask candidates for sensitive personal information during the application process (e.g., bank account details or social security number).
Veranova will never ask candidates for payment (e.g., for equipment, training, or background checks).
If you have any doubts or concerns about the authenticity of a job posting, please reach out to our HR department: ********************* (US) or ***************** (UK).
All your information will be kept confidential according to EEO guidelines.
Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law.
All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice.
Auto-ApplyScientist, Biologics
Scientist job in Watertown Town, MA
COMPANY INTRODUCTION Triveni Bio is breaking new ground in the identification of novel disease targets - working at the convergence of human genetics, best-in-class antibody design, and precision medicine. We are pioneering a Mendelian genetics-informed precision medicine approach to develop functional antibodies for the treatment of immunological and inflammatory (I&I) disorders. Our lead antibody program (TRIV-509) targets kallikreins 5 and 7 (KLK5/7) to directly impact skin barrier function, inflammation, and itch - providing a meaningful and much needed potential treatment option for patients with atopic dermatitis and other barrier disorders. In all the work we do, we adhere to our core values: patient impact, bold and rigorous science, open collaboration, kindness & respect.
SUMMARYTriveni Bio is in search of an innovative Scientist to join our Biologics team. In this role, you will design and optimize antibodies and proteins to advance Triveni's therapeutic pipeline. Your work will directly contribute to discovering new treatments for inflammatory diseases by improving library screening, data analysis, and protein engineering processes. On a day-to-day basis, you will design and test protein/antibody libraries using display technologies and analyze sequencing and screening data to identify high potential candidates. This is a unique opportunity to join a dynamic, cross-functional team where your contributions directly impact therapy development.KEY RESPONSIBILITIES:
Develop and optimize screening methods to improve functional protein recovery.
Analyze sequencing and high-throughput screening (HTS) data to guide design.
Apply computational tools for protein stability prediction and affinity maturation.
Collaborate with cross-functional teams including biology, bioinformatics, and automation teams to advance therapeutic pipelines.
Use computational tools (e.g., Rosetta, AlphaFold) to predict protein behavior and guide experiments.
Other duties as assigned.
QUALIFICATIONS:
A PhD in Protein Biochemistry, Bioengineering, Computational Biology, or a related field.
Hands-on experience with display technologies (yeast display required; phage/mammalian a plus) and protein library generation (e.g., error-prone PCR).
Proficiency in analyzing NGS/HTS data (Python/R, Bioconductor), familiarity with protein modeling software, and ability to integrate computational and experimental workflows.
Proficiency in Python/R for data analysis and familiarity with protein modeling tools.
Preferred (but not required):
Knowledge of machine learning/AI applications in protein design.
Industry experience in therapeutic antibody discovery/optimization.
Familiarity with antibody sequence-structure relationships.
$125,000 - $140,000 a year The posted range reflects the current reasonable and good faith estimate of the base salary for this full-time position. Actual compensation will be based on a variety of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location and other organizational needs. This role also offers a competitive target bonus, equity, and a comprehensive benefits package. We are committed to fair pay practices, and we regularly review our compensation programs to ensure they are competitive, equitable, and aligned with our values. Please note that the advertised pay range is not a guarantee or promise of a specific wage.
Triveni Bio, along with other biotech companies, has become aware of a surge in email scams targeting prospective job candidates within our industry. Official Triveni Bio applications will always be submitted through Lever, our ATS. Any applications that take you to other platforms could be fraudulent. We do not use text or chat applications to conduct interviews or make job offers. Official Triveni Bio correspondence will always be conducted from email addresses ending in @triveni.bio. Please disregard any other communication that does not originate from this domain name. If you receive any suspicious requests or communications, please verify their authenticity before responding.
Auto-ApplyBiology Scientist
Scientist job in Cambridge, MA
Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost.
• The purpose of this position is to provide support in evaluating various rodent genetic backgrounds in eliciting robust immune response within GBT.
• By performing phenotypic analysis of B cell compartment, deep sequencing of B cell repertoire, and studying antibody responses from immunized rodents, we will be able to understand the utility of these animals in biotherapeutic development.
• The incumbent, under the supervision by Pharmaceutical scientist, will be involved in the evaluation of the animals through the use of various immunogens, immunization approaches, and characterization method
Specific job description:
• Perform phenotypic analysis of lymphocyte compartments of rodents
• Perform deep sequencing of B cell repertoire of animals and analyze repertoire diversity pre and post immunization
• Immunize rodents using various strategies
• Characterize antibodies diversity post immunization
• Clone and express desired monoclonal antibodies for further analysis
Experience:
• Knowledge and work experience in the B cell phenotypic analysis by Flow Cytometry
• Knowledge and work experience in hybridoma generation
• Knowledge and work experience in rodent primary B cell culture
• Knowledge and work experience in Ig cloning from B cell
• Knowledge and work experience in affinity purification of polyclonal antibodies
• Knowledge and work experience in screening and functional assay development for selecting specific monoclonal antibodies
• Work experience in NGS of Ig repertoire
• Relevant industrial experience is preferred
Specific work plan:
a) Perform all aspects of phenotypic analysis of lymphocyte compartments of rodents
b) Perform, design and analyze B cell repertoire of rodents by deep sequencing
c) Perform and design immunization strategies and generate hybridoma
d) Evaluate and characterize immune response and monoclonal antibodies from desired rodents
e) Contribute to drafting relevant documentation such as immunization protocols, phenotypic and repertoire analysis reports and laboratory methods.
Qualifications
Bachelor's degree required
Additional Information
Best Regards,
Anuj Mehta
************
Research Associate/Associate Scientist, Assay Development
Scientist job in Woburn, MA
Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health.
Research Associate/Associate Scientist:
We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs.
This role is based onsite in our lab in Woburn, MA 5 days/wk.
Responsibilities:
Test and execute immunoassay workflows on high-throughput, semi-automated platforms
Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development
Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects
Assist in data analysis
Acquire necessary equipment and supplies for various projects
Qualifications:
Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab
Direct experience running biofluid-based immunoassays and qPCR experimentation is required
Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.)
Experience characterizing and troubleshooting immunoassays
Strong proficiency in molecular biology lab techniques
General Qualifications:
Self-motivated and ability to perform complex tasks in an effective manner
Ability to follow instructions and grow in a mentorship setting
Excellent organizational and documentation skills
Desire to learn and implement new technologies
Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team
Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position.
We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company.
Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.
Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
Auto-ApplyScientist I, Biology
Scientist job in Cambridge, MA
Wave seeks Scientist-I for Cambridge, MA location. Duties include:
Research Leadership & Competitive Intelligence
Conduct competitive intelligence research to evaluate targets for novel RNA therapies. Analyze scientific literature, industry reports, and competitive landscapes to identify novel disease targets and assess feasibility for antisense oligonucleotide (ASO) intervention. (10%)
Lead target discovery and validation programs by designing and overseeing experiments that investigate target biology, mechanism of action, and therapeutic potential of ASO candidates. Work closely with cross-functional teams to prioritize and advance promising targets. (10%)
Cross-functional & Strategic Leadership
Lead and manage multifunctional teams by driving collaboration between Chemistry, Biology, DMPK, and Toxicology teams to develop comprehensive preclinical strategies to advance ASO candidates. Serve as the scientific lead for target programs. (10%)
Participate in strategic decision-making with senior leadership on ASO program viability, target selection, and competitive positioning. Present findings to executive stakeholders to shape research priorities. (5%)
Preclinical & Translational Research
Independently lead and direct preclinical research programs to advance ASO therapeutics for rare and severe neurodegenerative diseases including Ataxias and other CNS indications. Define project scope, experimental strategy, and key milestones. (10%)
Manage and prioritize multiple in vivo pharmacology studies by defining study designs, analyzing PK/PD relationships, and driving strategic decision-making for candidate selection and optimization. Serve as primary point of contact for internal and external study partners. (10%)
Oversee development of new high-throughput in vitro assays to assess potency, efficacy, and cellular uptake of ASO therapeutics in patient-derived iPSCs, primary neurons, and astrocytes. Establish best practices and improve throughput efficiency. (8%)
Regulatory & External Engagement
Drive regulatory and scientific documentation, including drafting, reviewing, and finalizing study reports, Standard Operating Procedures (SOPs), and regulatory submissions and ensure compliance with industry standard and regulatory requirements. (10%)
Represent company at external scientific meetings, conferences, and partner collaborations to communicate study results, scientific insights, and research milestones. (10%)
Mentorship & Innovation
Mentor junior scientists, research associates, and cross-functional team members by providing technical guidance, performance feedback, and professional development support. (8%)
Drive new technology development initiatives by identifying and implementing novel methodologies for ASO delivery, target engagement, and efficacy assessment. (4%)
Laboratory Operations
Manage procurement and evaluation of external research tools, reagents, and technologies to optimize lab workflows and support experimental execution. (5%)
Position requires MS or foreign equivalent in Biotechnology, Molecular Biology, Neuroscience, Pharmacology, or related field and 4 years' experience in nucleic acid therapeutic research and development of antisense oligonucleotides (ASOs) for central nervous system (CNS) and neurodegenerative disorders. Experience must include the following (may be gained concurrently):
4 years' experience in competitive early stage research and screening of therapeutic targets for RNA and nucleic acid-based medicines to address severe neurodegenerative conditions.
4 years' experience designing and implementing experimental models for therapeutic target evaluation and validation and designing, executing, and analyzing large-scale SAR
Relationship (SAR) screens for ASOs utilizing transcriptomic and proteomic approaches to assess RNA-based interventions, optimizing SAR screening conditions across multiple cellular models, identifying lead compounds, and refining lead progression strategies for CNS and neuromuscular disorders.
4 years' experience developing and performing mechanistic studies to assess oligonucleotide activity including transcript and protein-level evaluations using RNA-seq, qPCR, and hybridization-based assays.
4 years' experience leading design and execution of in vitro PD, PK, and biodistribution studies and assessments in mouse models for ASO therapeutic candidates.
4 years' experience working with iPSCs, NPCs, and primary neurons including differentiation into disease-relevant neuronal subtypes for ASO screening and validation.
4 years' experience performing quantitative protein analysis for oligonucleotide therapeutics including ELISA, Western blotting, and amplicon sequencing to measure ASO-mediated protein modulation in CNS and peripheral tissues, and generating RNA and protein analysis workflows such as BRAVO (liquid handler), qPCR and MSD to assess drug-target interactions.
4 years' experience collaborating with cross-functional teams such as chemistry, toxicology, and DMPK groups to optimize lead candidate selection, analyze biodistribution results, and prepare preclinical data packages.
4 years' experience investigating impact of chemical modifications on target engagement, allele selectivity, potency, and duration utilizing stereopure phosphorothioate (PN) chemistry platform.
4 years' experience utilizing amplicon sequencing pipelines to validate allele selectivity in ASO-treated samples including SNP phasing, detection of allele-specific expression, and validation of knockdown selectivity in preclinical disease models.
2 years' experience leading large-scale preclinical oligo PK/PD studies to determine IC50 values, assess drug distribution, target engagement levels, and clearance in CNS and peripheral tissues, and generate critical dose-response data to support ASO therapies preclinical development .
2 years' industry experience preparing and reviewing regulatory documentation, including SOPs, preclinical study reports, and IND filings.
2 years' experience mentoring junior scientists in drug study design, bioassay development, and data interpretation using statistical tools such as GraphPad and JMP and implementing workflow optimizations such as KNIME workflow and ThinkCell software to enhance experimental reproducibility.
1 year experience presenting findings at scientific meetings, and/or external collaborations, including contributions to peer-reviewed publications.
6 months experience applying molecular biology techniques including RNA/DNA extraction, PCR and gel electrophoresis for at least 50 experiments in laboratory setting.
6 months' experience performing computational analysis of sequencing data using BLAST, SnapGene and Primer3 for sequence design and data interpretation.
#LI-DNI
Auto-ApplyScientist: Senior Quantum Optics, Atomic Physics Scientist
Scientist job in Cambridge, MA
Job Description
Please fully fill out our online application and upload your cover letter and resume or your application will not be considered.
Description of Company:
Nanobiosym stands at the forefront of transforming personalized medicine, breakthrough technologies, and global healthcare delivery. Founded by a distinguished MIT- and Harvard-trained Physician and Physicist, Nanobiosym develops pioneering platform technologies that leverage cutting-edge advances in physics, biomedicine, and nanotechnology.As the first-ever recipient of the XPRIZE for healthcare and the winner of multiple prestigious peer-reviewed research awards, Nanobiosym is expanding its world-class team as it transitions into a global commercial enterprise.Senior Quantum Optics, Atomic Physics ScientistWe are seeking an exceptional Senior Optical Physicist with deep expertise in experimental and applied optics. Ideal candidates will possess a PhD (or equivalent experience) in Experimental Physics, Optical Physics, Atomic Physics (Advanced Instrumentation, Signal to noise optimization), Electrical Engineering, or a related field, with 5+ years of hands-on research experience.Key Technical Qualifications
Extensive, hands-on optical bench expertise, including the design, construction, alignment, and maintenance of complex optical setups involving advanced laser sources.
Strong foundation in optical physics, with proven ability to model, analyze, troubleshoot, and refine sophisticated optical systems.
Experience in quantum optics and atomic physics, such as laser-matter interactions, single-molecule imaging, precision measurement techniques, advanced detection systems, or atomic-scale instrumentation
(preferred)
.
Demonstrated experience in laser trapping and laser cooling for cold atoms or related precision laser-based manipulation applications
(preferred)
.
Optical tweezers design and operation is required.
Mastery of high-precision optical alignment across multiple degrees of freedom.
Advanced programming proficiency in LabVIEW and MATLAB.
Strong competence in data acquisition, signal processing, and statistical analysis.
Experience working with acousto-optic modulators/deflectors and other high-precision photonics components.
Expertise in signal-to-noise optimization, including vibration isolation methodologies and noise-reduction strategies.
Additional experience with mechanical CAD, machine shop tools, and opto-mechanical design is a strong plus.
Professional Attributes
Highly organized, detail-oriented, and capable of managing multiple parallel projects within a fast-paced startup environment.
Demonstrates a proactive, solution-driven mindset with a strong "can-do" attitude.
Excellent communication, documentation, and interpersonal skills.
Thrives in an interdisciplinary environment working alongside physicists, engineers, biologists, entrepreneurs, and senior executives
Job Posted by ApplicantPro
Process Development Sr. Associate - Drug Product Technology
Scientist job in Cambridge, MA
Career CategoryOperationsJob DescriptionJoin Amgen's Mission of Serving Patients
At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.
Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Process Development Sr. Associate - Drug Product Technology
What you will do
Let's do this. Let's change the world. In this vital role you will join the Pre-Pivotal Drug Product, Synthetics Enabling Technologies (SET) team and support the characterization and development of small molecule drug candidates. This role is primarily laboratory-based and focuses on understanding physicochemical and biopharmaceutical properties that impact formulation design, stability, and oral bioavailability. The candidate will work closely with scientists on molecule assessment, solid-state characterization, and analytical teams to support early development programs.
Key Responsibilities include:
Conduct physicochemical profiling of small molecule drug candidates (e.g., solubility, pKa, logP/logD, hygroscopicity, dissolution, and chemical stability).
Assess developability risks by integrating experimental data on molecular properties.
Support material characterization to guide form selection and formulation strategy.
Perform solid-state analysis including X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), FT-IR, Raman spectroscopy, and solid-state NMR (as applicable).
Execute manual and automated high-throughput screening workflows. Prepare and characterize preclinical formulations (solutions, suspensions, solid dispersions, etc.) to enable in vivo studies.
Maintain accurate, detailed experimental records in electronic laboratory notebooks (ELN).
Document and interpret data to support regulatory filings and internal reports.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a collaborative individual with these qualifications.
Basic Qualifications:
High school diploma / GED and 6 years of Scientific experience OR
Associate's degree and 4 years of Scientific experience OR
Bachelor's degree and 2 years of Scientific experience OR
Master's degree
Preferred Qualifications:
B.S. in Chemistry, Chemical Engineering, Materials Science, Pharmaceutical Science, or a related scientific field, with at least two years of pharmaceutical/biotech industry experience.
Hands-on experience with solid-state and preformulation techniques.
Familiarity with data interpretation from XRPD, DSC, TGA, and spectroscopic methods.
Experience with high-throughput screening or automated liquid handling is desirable.
Strong attention to detail and commitment to data quality.
Effective communication and teamwork skills.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Apply now and make a lasting impact with the Amgen team.careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
.
Salary Range
85,306.00 USD - 103,484.00 USD
Auto-ApplyProcess Development Associate
Scientist job in Lexington, MA
A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.
With todays growing demand for talented and well qualified professionals, its more important than ever to partner with a company that employs innovative measures to meet your demands. Our expert team of highly trained counselors work hand in hand with every client forming a partnership of understanding and commitment. Our clients know that they can rely on us for prompt response times and reliable staff to meet their workforce demands. Our employees know that they can trust our support for their career development and personal growth.
IRI is proud to be JCAHO Certified by the Joint Commissions of Health, MBE Certified by the State of NJ and the National Minority Supplier Diversity Council (NMSDC) and SBE Certified by the State of NJ.
We have been honored by the following:
Top 100 Diversity Owned Business in NJ for 2007, 2008 and 2009
Top 500 Privately-Held Business in the US
Top 500 Diversity Owned Business in the US
Top 100 Subcontinent Asian American Business in the US
We have also been listed to the Inc. 5000 List of fastest-growing, privately-held companies in the US in 2007, 2008, 2009 and 2010 and honored as an Emerging Business of the Year finalist by NJ BIZ in 2009.
Job Description
Location- Lexington, MA Duration- 9m +++ Development Engineer / Associate (Contract) - Clinical Drug Product Manufacturing Sciences (CDPMS) The Development Engineer / Associate - CDPMS will assist drug product tech transfer teams with project management support. Project management support will include scheduling, resource planning, and project task tracking. A candidate with the right experience would have the opportunity to lead a drug product tech transfer team. The primary responsibility of the candidate will be to perform project management activities to manage the external manufacture of clinical trial materials. In addition, the candidate will coordinate external research projects such as compatibility and filter validation studies. Additional responsibilities will include performing drug product process development studies in collaboration with drug product manufacturing and formulation development teams. The Development Engineer / Associate will also analyze experimental data, document results and conclusions in technical reports, and assist Senior Staff with drug product tech transfer management projects. This will be a visible and hands on role with opportunities to contribute to multiple clinical stage programs. In this role, the Development Engineer / Associate must be able to work independently and be self-motivated. The candidate must manage time efficiently to balance multiple projects and priorities. Excellent organization and communication (oral and written) skills are required.
Qualifications
Qualifications • BS/MS in degree in chemical, biochemical, biomedical engineering, chemistry or related field • 3-6 years industry experience in formulation and/or drug product process development • Experience in supporting tech transfer projects to contract research and/or manufacturing organizations • Project management experience including time and resource scheduling • Experience in a GMP environment or GLP laboratory is preferred • Experience with Microsoft Project, Vizio, and advanced Excel spreadsheets is preferred • Experience managing outsourced research projects is a plus • Knowledge of statistical design of experiments is a plus
Additional Information
All your information will be kept confidential according to EEO guidelines.
Forensic Scientist III - Toxicology Unit
Scientist job in Maynard, MA
The Forensic Scientist III is a supervisory position within the Toxicology Unit of the Massachusetts State Police Forensic Services Division which analyzes postmortem and antemortem specimens for the Office of the Chief Medical Examiner and courts of the Commonwealth. This is the fully competent professional acting as the first-level supervisor for all toxicological work. Incumbents apply advanced principles, practices and techniques to the work performed. At this level, incumbents seek guidance and advice from more experienced colleagues and focus on gaining knowledge and experience to perform more independently and participate in work of higher complexity.
In addition to the functions performed at the Forensic Scientist Level I and II, incumbents at this level may perform the following:
* Supervise Forensic Scientists of a lower level within the unit as they identify, collect, preserve and examine evidence.
* Supervise Forensic Scientists of a lower level to manage caseloads and assignment and oversee production of results. Decide how work must be delegated and assigned to Forensic Scientists of a lower grade based upon caseload, staffing strengths and other personnel considerations.
* Lead activities, and provide training and direction in projects, processes, and functions where advanced subject matter knowledge is required.
* Provide training/technical assistance to Assistant District Attorneys, Office of the Chief Medical Examiner (OCME), police/fire personnel and other stakeholders on the collection and preservation of evidence, the results of laboratory testing and on laboratory operations.
* Perform and/or participate in validation studies/performance verifications for work groups or units.
* Participate in the training to Forensic Scientists of a lower level as required.
* Provide testimony as an expert and/or material witness in court and/or at formal judicial hearings in order to defend the findings of a test, examination or analysis, provide opinions on test results/examinations, demonstrate scientific procedures, and to explain test procedures and other job-related functions.
* Assist in the development of, review, revise, and follow protocols and procedures for all unit duties, as required.
* Ensure compliance with the laboratory's administrative policies, quality assurance/quality control requirements and ANAB accreditation standards.
* Implements quality control procedures; determines whether to accept or reject samples and/or materials sent to the laboratory for testing or analysis and assists in making necessary technical decisions to produce accurate results efficiently for all tests performed in the laboratory.
* Creates a positive work environment and effectively communicates with others.
* Performs all other related duties as assigned.
In addition to possessing the knowledge, skills and abilities required for Forensic Scientist II, incumbents are required to have the following at the time of hire:
* Knowledge of safety practices and procedures adopted in a forensic laboratory.
* Knowledge of chemistry research methods and procedures.
* Knowledge of legal terms and the legal process.
* Knowledge of how to direct subordinates in the proper techniques for handling, preserving, tracking and transporting samples and specimens used in a laboratory to preserve the integrity of the samples for presentation in a court of law.
* Ability to generate legal documents for use in the court system.
* Ability to take information about a case and determine what needs to be tested.
* Ability to give oral and written instructions in a precise and understandable manner.
* Ability to supervise, including planning and assigning work according to the nature of the job to be accomplished, the capabilities of subordinates and available resources; controlling work through periodic reviews and/or evaluations; motivating subordinates to work effectively and efficiently; and determining the need for and either recommending or initiating disciplinary action.
* Ability to gather information through questioning and observing individuals and by examining records and documents and determining the proper format and procedures for assembling the items of information.
* Ability to evaluate the quality of collected chemical data and/or physical evidence.
* Ability to interact effectively with and establish rapport with diverse teams and groups of people.
* Ability to understand and apply Massachusetts General Law and federal statutes, rules, regulations, policies, procedures, specifications, standards and guidelines governing assigned unit activities.
Note: Please review the minimum entrance requirements for this position. If you were never a fully competent forensic analyst within an accredited laboratory in a relevant forensic science specialization and have documented experience/training in providing testimony as both an expert and material witness in legal proceedings, do not apply, you will not be considered for this opening.
First consideration will be given to those applicants that apply within the first 14 days.
Minimum Entrance Requirements:
Applicants must have a Bachelors degree in the natural sciences, including Chemistry, Analytical Chemistry, Biochemistry, Biology, Forensic Science, Pharmacology or Physics and (A) at least three years of full-time, or equivalent part-time, professional experience as a bench chemist or forensic scientist in a crime laboratory or comparable setting and (B) full competence as a forensic analyst within an accredited laboratory in a relevant forensic science specialization, and documented experience in providing testimony as both an expert and material witness in legal proceedings, or (C) any equivalent combination of the required experience and the substitutions below.
Substitutions:
I. A Masters or higher degree in the natural sciences, including Chemistry, Analytical Chemistry, Biochemistry, Biology, Forensic Science, Pharmacology or Physics may be substituted for a maximum of one year of the required (A) experience.
Incumbents are required to have a current and valid motor vehicle drivers license at a class level specific to assignment.
Comprehensive Benefits
When you embark on a career with the Commonwealth, you are offered an outstanding suite of employee benefits that add to the overall value of your compensation package. We take pride in providing a work experience that supports you, your loved ones, and your future.
Want the specifics? Explore our Employee Benefits and Rewards!
An Equal Opportunity / Affirmative Action Employer. Females, minorities, veterans, and persons with disabilities are strongly encouraged to apply.
The Commonwealth is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity or expression, sexual orientation, age, disability, national origin, veteran status, or any other basis covered by appropriate law. Research suggests that qualified women, Black, Indigenous, and Persons of Color (BIPOC) may self-select out of opportunities if they don't meet 100% of the job requirements. We encourage individuals who believe they have the skills necessary to thrive to apply for this role.
Pharmaceutical Physical Properties Scientist
Scientist job in Groton, MA
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.
The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.
In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.
In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.
Job Description
* Analysis of powder samples for key physical properties (such as particle size distribution, bulk density, true density, powder flow, particle shape)
* Analysis of liquid samples for key physical properties (such as viscosity and surface tension)
* Using techniques such as optical microscopy, laser diffraction particle size analysis, electron microscopy, shear cell testing, compaction simulation, etc.
Qualifications
* Bachelor's degree in chemistry or other science related degree concentration, or equivalent directly-related experience
* At least one year experience in particle and powder characterization
* Strong computer, scientific, and organizational skills
* Proficient in learning new techniques, developing and carrying out experimental plans, and performing multiple tasks simultaneously
* Experience in data handling and scientific/engineering computations
* Excellent communication (oral and written) and attention to detail
* Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude
* Ability to keep accurate records, follow instructions, and comply with company policies
* At least one year experience in particle and powder characterization
Additional Information
* Position is full-time, Monday - Friday 8am to 5 pm
* Ability to work overtime as required.
* Tasks require repetitive motion and standing for long periods of time.
* May be required to respond to off-shift operational issues.
* Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
* Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
* Life and disability insurance
* 401(k) with company match
* Paid vacation and holidays
* #LI-EB1
* Authorization to work in the United States indefinitely without restriction or sponsorship
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.