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  • In Vivo Precision Oncology Scientist (HSO/SO)

    The Institute of Cancer Research 4.4company rating

    Scientist job in Chelsea, MA

    A leading cancer research institute in Chelsea is seeking a Scientific Officer or Higher Scientific Officer to conduct in vivo experiments aimed at optimizing vaccination approaches for treating cancers with homologous recombination defects. The ideal candidate will hold a current Home Office License, possess expertise in in vivo assays, and contribute to cutting-edge cancer research. This role offers a competitive salary, a supportive research environment, and opportunities for professional development. #J-18808-Ljbffr
    $65k-91k yearly est. 4d ago
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  • Principal Scientist, ADME-PK

    Dyne Tx

    Scientist job in Waltham, MA

    Our commitment to people with neuromuscular diseases Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more ************************* and follow us on X, LinkedIn and Facebook. Role Summary: The Principal S cientist , ADME-PK in Preclinical Development (PCD) department utilize s their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance Dyne 's efforts surrounding delivery of therapeutic payloads to muscle and CNS tissues with the FORCE platform . This role is based in Waltham, MA. Primary Responsibilities Include: Design and execute internal/external preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of Dyne's drug candidates Represent PCD as the ADME-PK subject matter expert on discovery and program teams Partner with and support Research, Toxicology, Translational Biomarkers, Clinical, Regulatory, Project Management and other Dyne departments Collaborate with Clinical Pharmacology/Pharmacometrics to develop quantitative tools to translate PK/PD relationship from preclinical to clinical Author high quality Regulatory documents including INDs, CTAs, and NDA/BLA filings. Prepare strategic and science-based ADME strategies that meet regulatory requirements and program goals Facilitate strategic scientific communication via meetings, abstracts and manuscripts Education and Skill Requirements: PhD in Pharmacokinetics, Pharmacology, Pharmaceutics, Biomedical Sciences or other relevant field with >6 years (MS with >8 years, BS with >12 years) of experience in the biopharmaceutical industry, with evidence of drug development experience Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamics and bioanalytical principles F amiliarity with regulatory submission including FIH dosing strategy is highly desirable Proficient in using WinNonlin or other pharmacokinetic software Excellent communication (verbal and written) and presentation skills, as well as interpersonal skills and the ability to represent PCD in a team environment Experience with PK characterization of protein therapeutics or antibody-drug conjugates (ADCs) is desired #LI-Onsite MA Pay Range $159,000 - $195,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. #J-18808-Ljbffr
    $159k-195k yearly 4d ago
  • Principal Scientist - Physics (REQ 298)

    Applied Physical Sciences Corp 4.1company rating

    Scientist job in Concord, MA

    Applied Physical Sciences (APS) is looking for a highly motivated Physical Scientist to join the Concord, MA team in a part-time, on-call (PTOC) position. Successful candidates will have a PhD in theoretical physics, expertise in inverse theory or tomography, and will support the development of state-of-the-art technologies for tomographic imaging with irregular experiment apertures, with a special emphasis on exploitation of high energy X-rays. APS works on exciting, technically challenging, cutting-edge technologies that will expose candidates to a wide variety of multidisciplinary fields, providing a stimulating environment with considerable opportunity for collegial interaction. At APS you will work in a small company environment where technical excellence is rewarded and an entrepreneurial spirit is encouraged, and you will have the chance to work directly with colleagues and customers that value innovation and creativity. Responsibilities Theoretical modeling of x-ray interaction physics, development of X-ray inversion paradigms for highly challenging experiment scenarios, rigorous characterization of the fundamental information limits of X-ray imaging. Software implementation of processing and modeling techniques, numerical execution of synthetic inversion experiments, display and quantification of model uncertainty Required Attributes and Skills PhD in theoretical physics, and expertise in modeling and inversion of X-ray data Subject matter expertise in one or more of the following: advanced numerical optimization, statistical methods, experiment design optimization, GPU-based computing Extensive experience with computational methods and programming for modeling physical phenomena and processing of real data e.g., Matlab, Python, PyTorch, or Fortran Exceptional communication skills (written and oral) for technical documentation and reviews with customers Desired Attributes and Skills Professional experience of 10+ years in DoD or related industry, a strong publication history in refereed technical journals, and a track record of successful performance on research programs under DARPA, IARPA, NAVSEA or ONR sponsorship is preferred. Experience as principal investigator working on advanced R&D programs Demonstrated technical leadership in modeling and simulation Expertise in one or more of the following: mathematical physics, model-based iterative methods for x-ray tomography, Monte Carlo radiative transport methods for Bremsstrahlung modeling, advanced numerical optimization techniques involving both continuous and discrete variables, regularization methods, uncertainty quantification using the Fisher Information Matrix and the Cramer-Rao Bound, and multi-objective optimization. Experience presenting talks at technical conferences APS, a wholly owned subsidiary of the General Dynamics Corporation, offers a small company environment including competitive salary, excellent benefits, and comfortable working conditions. This is a part-time on-call position open in the Concord, MA office. Candidates must possess or be able to obtain a Top Secret DOD security clearance. Qualified applicants are invited to submit a resume and application online at **************** fax them to ************, Attn: Human Resources, or mail to the company address. Please reference the requisition number and title of the position in the subject line of your submission. Equal Opportunity Employer/M/F/Disability/Protected Vet Invitation to Self-Identify In keeping with our commitment to Equal Employment Opportunity (EEO), Applied Physical Sciences invites all applicants to self-identify pre-offer as a protected veteran and/or an individual with a disability. Invitation to Self-Identify as Protected Veteran Online Form Invitation to Voluntary Self-Identification of Disability Online Form #J-18808-Ljbffr
    $90k-127k yearly est. 3d ago
  • Principal AI/ML Scientist, Drug Discovery

    Scipro

    Scientist job in Cambridge, MA

    About the job: SciPro is partnered with a fast growing Scientific Data and AI platform startup who is searching for a Senior Applied AI/ML Engineer to join their team. They are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data across the scientific value chain and scientific vertices. They bring this AI data to life in a fast growing suite of universal lab data management solutions, scientific use cases, and AI-based scientific outcomes. Requirements: You will be a critical team member in a unique partnership to industrialize Scientific AI. As such, you will engage directly with customers onsite up to 4-5 days per week in the Boston region. Advanced degree in Biological, Data, or Computer Science Portfolio demonstrating end-to-end ownership of AI/ML products Proven track record of deploying AI models addressing real world problems Experience in biotech, biopharma, or pharma-adjacent projects Superior talent developing at least one of: ML-Reinforcement Learning, LLM/NLP, or Protein Design/Diffusion Models Responsibilities: Responsible for designing, developing, training, and validation of AI/ML products Support and advise executive leadership regarding technical and commercial feasibility Work with commercial teams to understand the impact of AI in life-sciences Collaborate with cross functional teams to build products Preferred Qualifications: Deep understanding of hurdles facing pharmaceutical drug development Demonstrated ability to make productized applications (for use by more than one group) Excellent communication skills Ability to advocate and evangelize for AI initiatives internally and externally Experience collaborating with teams on large software projects
    $92k-129k yearly est. 2d ago
  • Senior Assay Development Scientist/Engineer

    Siphox Health

    Scientist job in Burlington, MA

    +++ SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker. We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing. +++ The Opportunity +++ We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today. This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels. +++ What You'll Do +++ Core Assay Development Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform. Design, execute, and interpret experiments focused on: Binding kinetics & equilibrium optimization Surface functionalization strategies Competitive assay dynamic-range shaping Calibrator and control development (matrix selection, commutability) Assay precision, stability, robustness Analytical Performance & Validation Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17). Establish and demonstrate performance for: Analytical sensitivity & functional limit (LoB/LoD/LoQ) Linearity & reportable range (including hook effects, competitive assay inflection characterization) Repeatability, reproducibility, and nested CV analysis Interference and cross-reactivity studies Matrix equivalency & recovery studies Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks). Cross-Functional Integration Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance. Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing. Documentation & Execution Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations. Present results across the company to inform design decisions and product milestones. +++ What We're Looking For +++ Technical Background PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields. Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus. Demonstrated ability to independently solve complex analytical and biochemical problems. Hands-on experience with complex analytical workflows, assay automation, and instrumentation. Strong understanding of calibration design, commutability, and control strategies. Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks. Regulatory & Platform Experience (Bonus) Experience with IVD development, ISO 13485, or 21 CFR 820. Experience with POC or novel-platform assay development. Knowledge of label-free sensors, waveguides, or photonic resonance systems. Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation. Personal Traits Strong scientific intuition paired with rigorous data discipline. Thrives in a fast-paced, milestone-driven startup environment. Creative problem solver willing to challenge established assay paradigms. High integrity, willingness to own outcomes, and a collaborative mindset. +++ Why This Role Is Unique +++ Most assay developers spend their careers optimizing assays on platforms that already exist. At SiPhox, you will: Build the first generation of photonic immunoassays deployed in consumer health. Design assays whose constraints are shaped by semiconductor physics as much as biochemistry. Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins. See your work ship in a product used at home by real people, not just research labs. If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.
    $64k-94k yearly est. 2d ago
  • Research Associate I

    Pyramid Consulting, Inc. 4.1company rating

    Scientist job in Framingham, MA

    Immediate need for a talented Research Associate I. This is a 06+ Months Contract opportunity with long-term potential and is located in Framingham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested. Job ID:26-01448 Pay Range: $34 - $44/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location). Key Responsibilities: Require to be on site daily; Weekend work required occasionally. Plan and execute experiments to optimize upstream cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.) Perform upstream experiments and collaborate with other functional groups to speed Phase I pipeline projects Contribute to technical reports, experimental protocols, and technical summaries for presentation internally and externally Participate in the technology transfer of processes into manufacturing facilities Ensure safety and environmental compliance are maintained in the workplace Some weekend working may be required for this role. Key Requirements and Technology Experience: Must have skills: - Understanding of aseptic technique and principles of mammalian cell culture, Cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.) Bachelor or Master's degree in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline Post-education experience ?=3 years Understanding of aseptic technique and principles of mammalian cell culture Detailed in lab operations and quick learner for new technologies. Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors Knowledge of CMC Note- Weekend works is required and is occasionally. This is a rotating, schedule 1-4 hours on 1 weekend day and will include a Saturday or Sunday. This will be included in 40 work week and no to exceed 40 hours. Weekend work is pre-planned through end of year; new hire can swap with colleagues if available. Our client is a leading Pharmaceutical Industry, and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration. Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.
    $34-44 hourly 2d ago
  • Machine Learning Scientist, AI Explainability

    SES 4.2company rating

    Scientist job in Woburn, MA

    About Us: SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology. Harness internal expertise and collaborate with external research labs to advance scientific ML. Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery. This position can be remote. Essential Duties and Responsibilities: Research & Development Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery. Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference. Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions. Model Optimization & Implementation Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency. Implement innovative solutions to enhance model performance and scalability. Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology. Collaboration & Communication Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences. Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently. The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members. Education and/or Experience: MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience. Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models. Proficiency in programming languages relevant to machine learning, with a strong preference for Python. Experience with deep learning frameworks such as PyTorch or TensorFlow. Proficiency in utilizing causal graphs for AI research and application. A solid track record of innovative research, preferably with published work in relevant areas. Excellent problem-solving abilities and a passion for tackling complex technical challenges. Preferred Qualifications: Experience with AI applications in material science or battery technology. Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.
    $70k-103k yearly est. Auto-Apply 43d ago
  • Scientist I/II, Nucleic Acid Chemistry

    Alloy Therapeutics 3.8company rating

    Scientist job in Waltham, MA

    The Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of "Mentorship-By-Apprenticeship" in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team The Alloy Genetic Medicines group is innovating a novel RNA-based drug discovery platform, namely "AntiClastic", spanning the fields of antisense therapeutics to immunomodulating therapeutics. This technology platform was launched by Alloy in 2023 after exclusively licensing its underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works closely with external partners to discover and develop AntiClastic RNA medicines. The Role This position reports to the Head of Nucleic Acid Chemistry. We are seeking a detail-oriented Nucleic Acid Chemistry Scientist to join our growing Nucleic Acid Chemistry team supporting the CMC development of oligonucleotides, mRNA, pDNA templates, and antibody-oligonucleotide conjugates (AOCs). The successful candidate will bring strong hands-on expertise in synthesis and purification of nucleic acids, as well as HPLC and LC-MS analytics for RNA, DNA, and nucleic acid medicines. You will have a proven track record of developing, documenting, qualifying, and troubleshooting analytical methods and production processes in a fast-paced industrial environment. This role also requires experience working with and managing Contract Research Organizations (CROs), and developing/synthesizing reference materials to enable method development and program progression. This role may be filled at Scientist I or Scientist II depending on experience and demonstrated level of independence. Principal Responsibilities Synthesis and Process Development * pDNA Production: Execute microbial fermentation (E. coli) for plasmid DNA amplification; perform harvesting, lysis, and purification of pDNA. * Linearization: Perform enzymatic restriction digests to linearize pDNA templates for downstream transcription. * mRNA Synthesis: Lead in vitro transcription (IVT) reactions to produce mRNA, including enzymatic capping (Cap 1) and poly-adenylation. * Oligonucleotide: Execute procedures to synthesize oligonucleotides. * Purification: Utilize TFF (Tangential Flow Filtration) and chromatography (IEX, HIC, or Affinity) to purify intermediates and finished products from process-related impurities. Analytical Method Development & Qualification * Develop, optimize, document, qualify, and transfer phase-appropriate analytical methods to support CMC activities for oligonucleotides, mRNA, pDNA, and AOCs. * Design fit-for-purpose methods for identity, purity, integrity, potency/assay, and stability, including forced-degradation studies. * Lead method qualification/verification activities for nucleic acid CQAs (e.g., product related purity, drug antibody ratios, mRNA capping efficiency, poly-A tail length, and residual template DNA). * Execute and interpret analyses using HPLC/UPLC modalities (e.g., IPRP, AE, IEX, HILIC, SEC). * Perform and interpret LC-MS analyses for intact oligos, mRNA mapping, sequence confirmation, impurity ID, and conjugate characterization. * Independently troubleshoot instrument and method issues, ensuring data integrity and project continuity. Reference Materials Development * Develop, qualify, and maintain analytical reference materials (e.g., standards, system suitability controls, impurity markers) to support method development, stability programs, and release testing. * Coordinate and/or perform internal synthesis (chemical or enzymatic) of oligonucleotide and mRNA reference materials and related controls. * CRO / External Partner Management * Work effectively with and manage CRO/CDMO partners executing analytical studies, method development, or mRNA/pDNA manufacturing. * Author, review, and approve CRO protocols, reports, data packages, and method documentation. Documentation & Data Integrity * Document experiments in real time with excellent attention to detail in electronic lab notebooks. * Support regulatory-compliant documentation for IND/BLA/MAA filings and respond to technical inquiries. Qualifications * Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2-5 years of industry experience in nucleic acid synthesis or analytical development. * Hands-on experience in pDNA, mRNA, and oligonucleotide production: Including microbial fermentation, pDNA purification, linearization, and in vitro transcription (IVT), solid-phase synthesis, & lyophilization. * Extensive hands-on experience with HPLC/UPLC and LC-MS applied to mRNA, pDNA, oligonucleotides, and/or oligonucleotide conjugates. * Demonstrated success developing and qualifying analytical methods for nucleic acids (e.g., Capillary Electrophoresis/Fragment Analyzer for mRNA integrity). * Experience developing, synthesizing/sourcing, characterizing, and maintaining reference materials/standards. * Proven experience working with and managing CRO and/or CDMO partners. * Strong understanding of nucleic acid challenges (e.g., RNase-free handling, secondary structures, ion-pairing reagents, sequence variants, and conjugation heterogeneity). * Experience with antibody-oligonucleotide conjugates (AOCs) and LNP-formulated mRNA. (Preferred) * Familiarity with GMP/GLP environments and regulatory expectations for method lifecycle management. (Preferred) * Hands-on knowledge of complementary techniques (e.g., qPCR/dd PCR, SEC-MALS, and biophysical assays). (Preferred) Taking Care of Our People We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one. Compensation * Competitive base and equity compensation commensurate with level of experience and independence * 401(k) company match Health & Family * Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered * Company-paid disability (STD, LTD) and life insurance * Paid parental leave * Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval) Unique Perks * Unlimited PTO (paid time off) and flexible schedules * Annual stipend for continuing education with commitment to your career through individualized professional development plan * Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness Pay Transparency At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $126,000 - $144,000 with the final offer based on factors like your experience, skills, and alignment with our needs. Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team's professional and personal well-being. If you have any questions about pay or benefits, we're here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected]. We will make every effort to respond to your request for disability assistance as soon as possible.
    $126k-144k yearly 23d ago
  • Scientist I

    Boston Analytical 4.2company rating

    Scientist job in Salem, NH

    Job DescriptionSalary: The Scientist will contribute to Extractables & Leachables studies performed in the E&L laboratory at Boston Analytical to support client submissions. The ideal candidate will have experience operating LC-MS and GC-MS systems for analysis of volatile, semi-volatile, and nonvolatile organic extractables and leachables samples. PRIMARY DUTIES AND RESPONSIBILITIES Prepares extractions for analysis. Analysis of sample extract solutions by GC-MS and LC-MS to adequately resolve and identify all compounds. Coordinate findings with the team to generate conclusions. Author detailed cGMP report sections for work performed outlining study findings. Develop analysis methods for drug product leachables testing. Performs system maintenance and calibrations to ensure equipment is operating with specified requirements. Ensures all work performed strictly adheres to Company, client and Pharmacopial requirements. Proper handling of hazardous waste in compliance with the Company and DES hazardous waste rules. REQUIREMENTS & QUALIFICATIONS Qualification includes a Ph.D. in Analytical Chemistry with 2+ years experience or a Masters degree and 4+ years experience or a Bachelors with 6+ years of experience performing and interpreting MS analysis. Knowledge of current Extractable & Leachables guidance (USP, ISO 10993) and best practices preferred. Experience working in a cGMP environment required. MINIMUM SKILLS REQUIREMENTS Must have the ability and skill to perform the detailed job requirements noted above competently, safely and proficiently. A self-starter, motivated person who possesses good interpersonal skills capable of effectively interacting with all departments and client personnel. Must have excellent organizational, verbal communication and technical writing skills. Must be a team player with integrity and concern for the quality of Company products, services and staff members. Demonstrated LC-MS and/or GC-MS operation and data interpretation capability. Ability to develop and optimize HPLC, UPLC, and GC methods. Documented success managing complex projects to completion within customer expectations for deadline, cost, and overall deliverable
    $63k-93k yearly est. 12d ago
  • Product Development Scientist

    Ajinomoto Health & Nutrition North America

    Scientist job in Ayer, MA

    About Us Eat Well, Live Well. At Ajinomoto Cambrooke, we build careers grounded in helping improve people's health through nutritional therapies. Ajinomoto Cambrooke (ACI) was founded by parents looking to develop better solutions for their children with PKU. Over the subsequent 25 years, we have expanded into additional therapeutic areas with a focus on enjoyable nutrition as a core part of normalizing the life for people living with medical conditions. Joining ACI means becoming part of a diverse team of talented people who want to build their careers while contributing back to society in a positive way. We seek individuals who bring an entrepreneurial mindset with a bias for action and finding solutions. We provide an environment based in mutual respect and collaboration to support you and give you opportunities to learn and develop. Join us to find a rewarding work experience that lets you be at your best and have an impact on our patient communities. Why Join Us Our people are the key ingredient to our success. We offer a collaborative, innovative environment where you can grow your career and make an impact on global food and health solutions. We provide a comprehensive and competitive total rewards package, including: • Competitive Pay and Annual Bonus Opportunity • 401(k) with Company Contributions • Medical, Dental, and Vision - Effective Day 1 • Paid Time Off, Company Holidays, and Floating Holidays • Paid Parental Leave • Wellness Programs and Yearly Wellness Reimbursement • Work Flexibility • Company-Paid Life and Disability Insurance • Employee Assistance Program (EAP) • Tuition Reimbursement Opportunities • Career Growth and Development within a Global Organization • Company-Provided Mental Health and Caregiving support Overview The Product Development Team supports the medical nutrition business by developing new and revising existing product formulations to meet target characteristics that will deliver positive patient outcomes through therapeutic nutrition. Strong collaboration with the Directors of Medical Nutrition, Marketing, and Sales will be required to ensure desired nutritional levels are achieved throughout the product shelf-life, patient insights on flavor, texture, and palatability are incorporated. In this role, you will contribute to the ideation and exploration for uses of new to ACI ingredients and new to ACI business ventures in additional disease-states reliant on specialized medical nutrition. This position sits in our Corporate Office located in Ayer, MA. Qualifications EDUCATION, CERTIFICATIONS AND EXPERIENCE: • Minimum bachelor's in food science, nutrition, or related field; Master's degree preferred. PhD, PharmD a plus. • 5+ years of experience in product development, with ability to take concepts from bench top to commercialization for nutritional beverages and / or nutritional powder blends from concept to commercialization. • 5+ years in basic and applied research and development preferably in small/mid-sized nutrition, food and/or biotech company. Experience with food/beverage formulation and manufacture of nutritional products that meet stability, sensory and nutritional requirements. Direct experience with aseptic processing / Tetra Pak a plus. • Expert scientific knowledge in food science with emphasis on product development involving interaction amongst ingredients and impact of process techniques on use of micro-nutrients. • Experience with nutritional modeling software and familiarity with FDA regulations preferred, exposure to EU regulations a plus. • Able to design and monitor product shelf-life procedures both regular and accelerated for nutritional products. • Strong translational science background with experience in converting basic nutrition-science insights into consumable products. KNOWLEDGE, SKILLS AND ABILITIES: • Build relationships with vendors to source ingredients to meet product specifications. • Overall understanding of how business units interact to facilitate successful product development and commercialization. • Ability to define new product needs in terms of process needs and product characteristics including organoleptic needs / claims • Demonstrated Leadership capability with a focus on innovation to drive product development proactively and passionately. • Exhibit the understanding of use of standard operation procedures related to product development, process development and product shelf-life determination. • Well versed with food safety requirements and regulations. • An understanding of human nutrition and ability to review primary scientific literature. • A strong ability to communicate basic science and technical challenges to non-technical audiences. • A strong understanding of ingredient interactions in a food/beverage matrix throughout processing and shelf life. • Ability to design shelf-life evaluation matrices considering product composition, process impact and other critical factors when designing new products in medical nutrition arena. • An understanding of macro and micro-nutrient analytical procedures and their principles. • Ability to work in a fast paced, cross functional team environment. • Excellent analytical skills, strong attention to details, good communication and interpersonal skills. • Excellent organizational skills, the ability to balance multiple projects, set priorities, and drive results. Working Conditions / Physical Requirements WORKING CONDITIONS: This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. as required PHYSICAL REQUIREMENTS: Position requires the ability to occasionally lift up to 50 pounds, stand, walk, bend, reach, push, and pull. Ability to use a computer, keyboard, telephone, and other office equipment. Ability to wear all required PPE. Responsibilities • Utilize your exemplary food science and ingredient know-how to co-create and execute medical formula products against ACI's strategic R&D roadmap to support the overall corporate strategy while meeting the internal quality expectations. • Support the Leadership and Management teams with scientific support in the areas of product development, clinical development, product manufacturing and new ingredient compound / product initiatives. • Research and help develop clinical evidence supporting existing and new products and ingredient compounds for use in commercial activities. • Participate in conferences, clinician meetings and other forums to present ACI's clinical evidence. • Ensure existing and new products, processes or ingredient compounds have strong Intellectual Property protection thus providing ACI a sustained competitive advantage. • Other duties as assigned. Salary Range $105,000 - $130,000 Annual with potential 12.5% Bonus EEO Statement Ajinomoto Cambrooke, Inc. is an Equal Opportunity Employer-Vets/Disabled, committed to a diverse workforce. If you need assistance with completion of an application for employment, please contact Human Resources Department at ************.
    $105k-130k yearly Auto-Apply 60d+ ago
  • Product Development Scientist

    Head-Huntress.com

    Scientist job in Ayer, MA

    Job DescriptionProduct Development Scientist - Medical Nutrition Industry: Food Production / Medical Nutrition Experience: Mid-Level (5+ years) Education: Bachelor's degree required Positions: 1 Relocation: Limited assistance available Visa Sponsorship: Not available Overview Seeking a Product Development Scientist to develop and optimize medical nutrition beverage and powder formulations in a manufacturing environment. This role supports product innovation, ingredient initiatives, clinical evidence development, and compliance with GMP and food safety standards. Responsibilities Develop and optimize nutritional beverage and powder formulations Conduct bench-level formulation, testing, and troubleshooting Execute shelf-life and stability studies Research and evaluate new ingredients Support scale-up, manufacturing, and commercialization activities Collaborate with cross-functional teams (R&D, Quality, Manufacturing, Commercial) Ensure compliance with GMP and food safety requirements Support documentation and IP protection efforts Additional Info On-site role in Ayer, MA Limited relocation assistance available No visa sponsorship available JD Summary:Develop and optimize medical nutrition beverage and powder formulations; apply food science and ingredient expertise; collaborate with Medical Nutrition, Marketing, Sales, Manufacturing; research new ingredients; support clinical evidence development; manage ingredient vendors; support IP protection; ensure GMP, food safety, and workplace safety compliance; participate in conferences and clinician meetings; support manufacturing and new product initiatives. RequirementsRequirements Bachelor's degree in Food Science, Nutrition, or related field (Master's preferred) 5+ years of product development experience in food, beverage, medical nutrition, supplement, or nutraceuticals Strong knowledge of ingredient functionality and nutrient stability Experience with GMPs and FDA food regulations Hands-on lab and pilot-scale experience required PLM or formulation software experience preferred
    $75k-100k yearly est. 13d ago
  • Product Development Scientist - Medical Nutrition (Onsite) | Ayer, MA

    Confidential Recruiting Partners

    Scientist job in Ayer, MA

    Our client is seeking a Product Development Scientist to develop and optimize medical nutrition beverages and powder formulations that support patient outcomes and clinical evidence. This role combines hands‑on bench formulation, ingredient research, stability testing, and cross‑functional collaboration across R&D, Clinical, Manufacturing, and Marketing. You will play a key role in advancing the company's medical nutrition portfolio, supporting new product innovation, ingredient initiatives, and regulatory compliance. Onsite | No Visa Sponsorship | Relocation Assistance: Limited Responsibilities: Formulation & Product Development Execute sensory, stability, and shelf‑life studies. Develop and optimize medical nutrition beverages and powders. Conduct bench‑level formulation, testing, and troubleshooting. Evaluate ingredient functionality, nutrient stability, and processing impact. Cross‑Functional Collaboration Partner with Medical Nutrition, Marketing, Sales, and Clinical teams. Support clinical evidence development for new and existing products. Present scientific findings at conferences and clinician meetings. Ingredient & Vendor Management Research new ingredients and medical nutrition opportunities. Manage vendor relationships and source compliant ingredients. Regulatory, Quality & Compliance Ensure adherence to GMP, food safety, and FDA regulations. Support IP protection for formulations, processes, and ingredients. Additional Responsibilities Perform other duties as assigned. Provide scientific support across R&D and manufacturing. Participate in pilot plant trials and scale‑up activities. Qualifications/Must Haves: Familiarity with GMPs and FDA regulations. Experience conducting shelf‑life and stability studies. Proven bench‑level formulation and troubleshooting experience. Strong understanding of ingredient functionality and nutrient stability. Bachelor's degree in Food Science, Nutrition, or related field (Masters preferred; PhD/PharmD a plus) 5+ years of hands‑on product development experience in food, beverage, nutrition, supplement, or nutraceutical industries. Preferred Skills: Exposure to EU regulatory frameworks. Experience with PLM systems and nutritional formulation tools. Experience with aseptic processing or medical nutrition products. Experience in small to mid‑sized food or medical nutrition companies.
    $75k-100k yearly est. 6d ago
  • Biology Scientist

    Artech Information System 4.8company rating

    Scientist job in Cambridge, MA

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. • The purpose of this position is to provide support in evaluating various rodent genetic backgrounds in eliciting robust immune response within GBT. • By performing phenotypic analysis of B cell compartment, deep sequencing of B cell repertoire, and studying antibody responses from immunized rodents, we will be able to understand the utility of these animals in biotherapeutic development. • The incumbent, under the supervision by Pharmaceutical scientist, will be involved in the evaluation of the animals through the use of various immunogens, immunization approaches, and characterization method Specific job description: • Perform phenotypic analysis of lymphocyte compartments of rodents • Perform deep sequencing of B cell repertoire of animals and analyze repertoire diversity pre and post immunization • Immunize rodents using various strategies • Characterize antibodies diversity post immunization • Clone and express desired monoclonal antibodies for further analysis Experience: • Knowledge and work experience in the B cell phenotypic analysis by Flow Cytometry • Knowledge and work experience in hybridoma generation • Knowledge and work experience in rodent primary B cell culture • Knowledge and work experience in Ig cloning from B cell • Knowledge and work experience in affinity purification of polyclonal antibodies • Knowledge and work experience in screening and functional assay development for selecting specific monoclonal antibodies • Work experience in NGS of Ig repertoire • Relevant industrial experience is preferred Specific work plan: a) Perform all aspects of phenotypic analysis of lymphocyte compartments of rodents b) Perform, design and analyze B cell repertoire of rodents by deep sequencing c) Perform and design immunization strategies and generate hybridoma d) Evaluate and characterize immune response and monoclonal antibodies from desired rodents e) Contribute to drafting relevant documentation such as immunization protocols, phenotypic and repertoire analysis reports and laboratory methods. Qualifications Bachelor's degree required Additional Information Best Regards, Anuj Mehta ************
    $66k-96k yearly est. 60d+ ago
  • Research Associate/Associate Scientist, Assay Development

    Spear Bio

    Scientist job in Woburn, MA

    Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health. Research Associate/Associate Scientist: We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs. This role is based onsite in our lab in Woburn, MA 5 days/wk. Responsibilities: Test and execute immunoassay workflows on high-throughput, semi-automated platforms Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects Assist in data analysis Acquire necessary equipment and supplies for various projects Qualifications: Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab Direct experience running biofluid-based immunoassays and qPCR experimentation is required Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.) Experience characterizing and troubleshooting immunoassays Strong proficiency in molecular biology lab techniques General Qualifications: Self-motivated and ability to perform complex tasks in an effective manner Ability to follow instructions and grow in a mentorship setting Excellent organizational and documentation skills Desire to learn and implement new technologies Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position. We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company. Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability. Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.
    $69k-97k yearly est. Auto-Apply 53d ago
  • iPSC Production Scientist - Biology

    ZP Group 4.0company rating

    Scientist job in Medford, MA

    Piper Health & Sciences is seeking a full-time iPSC Production Scientist to join a growing organization's Bio/Engineering Production team onsite at their Massachusetts location. The ideal candidate will have a strong biology background and hands-on experience in iPSC stem cell culture, differentiation, and QC within a pharmaceutical or biotech environment. Responsibilities of the iPSC Production Scientist Include: * Full-time onsite schedule: Monday-Friday, 9:00 AM - 5:00 PM * Lead and support iPSC production and related lab activities * Perform hands-on stem cell culture and differentiation * Execute QC-related tasks in accordance with SOPs * Maintain accurate lab documentation and records * Support Bio/Engineering Production workflows * Follow all safety, GMP, and GLP standards Qualifications of the iPSC Production Scientist Include: * Biology degree is strongly preferred (Biomedical Engineering degrees are NOT a fit) * Proven hands-on experience with: * iPSC cell culture * Stem cell differentiation * Quality Control (QC) processes * Pharmaceutical or biotech industry experience preferred Compensation of the iPSC Production Scientist Includes: * Salary Range: $83,200.00 - $114,000.00 per year (equivalent to $40.00 - $55.00 per hour), based on experience and certifications. * Comprehensive Benefits: CIGNA Medical, Dental, Vision; 401k through ADP and sick leave as required by law. * Ability to work with a well renowned and growing organization that has a robust pipeline and quality culture. This job opens for applications on 1/12/2026. Applications for this job will be accepted for at least 30 days from the posting date. #LI-AW1 #LI-ONSITE keywords: Scientist, iPSC Production, stem cell culture, induced pluripotent stem cells, cell differentiation, quality control, QC, laboratory scientist, cell biology, biotechnology, pharmaceutical production, bioengineering, GMP, GLP, SOP compliance, tissue engineering, regenerative medicine, bioprocessing, cell therapy, stem cell research, lab operations, onsite scientist, Medford MA jobs, contract scientist, PhD biology, master's biology, postdoctoral research, biotech scientist, pharma scientist, cell culture specialist, stem cell specialist, iPSC scientist, QC scientist, bio production scientist, laboratory techniques, cell-based assays, biotech careers, pharma careers, stem cell manufacturing, cell culture workflows, life sciences jobs, biopharma jobs, laboratory compliance, scientific documentation, biotech industry experience, pharmaceutical industry experience, cell line development, research scientist, production scientist, laboratory QC, stem cell differentiation protocols, cell culture maintenance, full-time onsite scientist, bioengineering production team, regenerative biology, tissue culture, cell therapy manufacturing, biotechnology research, pharmaceutical QC, biomanufacturing, cell biology techniques, stem cell QC testing, scientific method, laboratory safety standards, GMP compliance, GLP compliance, biotech contract role, scientist contract position, iPSC culturing, stem cell production, biotech Medford MA, pharma Medford MA, scientific careers, laboratory scientist jobs, cell therapy scientist, bioprocess scientist, QC laboratory scientist, stem cell lab work, biotech production workflows, pharmaceutical production workflows, life sciences contract jobs, biotech contract scientist, pharma contract scientist.
    $83.2k-114k yearly 19d ago
  • Scientist: Senior Quantum Optics, Atomic Physics Scientist

    Nanobiosym

    Scientist job in Cambridge, MA

    Job Description Please fully fill out our online application and upload your cover letter and resume or your application will not be considered. Description of Company: Nanobiosym stands at the forefront of transforming personalized medicine, breakthrough technologies, and global healthcare delivery. Founded by a distinguished MIT- and Harvard-trained Physician and Physicist, Nanobiosym develops pioneering platform technologies that leverage cutting-edge advances in physics, biomedicine, and nanotechnology.As the first-ever recipient of the XPRIZE for healthcare and the winner of multiple prestigious peer-reviewed research awards, Nanobiosym is expanding its world-class team as it transitions into a global commercial enterprise.Senior Quantum Optics, Atomic Physics ScientistWe are seeking an exceptional Senior Optical Physicist with deep expertise in experimental and applied optics. Ideal candidates will possess a PhD (or equivalent experience) in Experimental Physics, Optical Physics, Atomic Physics (Advanced Instrumentation, Signal to noise optimization), Electrical Engineering, or a related field, with 5+ years of hands-on research experience.Key Technical Qualifications Extensive, hands-on optical bench expertise, including the design, construction, alignment, and maintenance of complex optical setups involving advanced laser sources. Strong foundation in optical physics, with proven ability to model, analyze, troubleshoot, and refine sophisticated optical systems. Experience in quantum optics and atomic physics, such as laser-matter interactions, single-molecule imaging, precision measurement techniques, advanced detection systems, or atomic-scale instrumentation (preferred) . Demonstrated experience in laser trapping and laser cooling for cold atoms or related precision laser-based manipulation applications (preferred) . Optical tweezers design and operation is required. Mastery of high-precision optical alignment across multiple degrees of freedom. Advanced programming proficiency in LabVIEW and MATLAB. Strong competence in data acquisition, signal processing, and statistical analysis. Experience working with acousto-optic modulators/deflectors and other high-precision photonics components. Expertise in signal-to-noise optimization, including vibration isolation methodologies and noise-reduction strategies. Additional experience with mechanical CAD, machine shop tools, and opto-mechanical design is a strong plus. Professional Attributes Highly organized, detail-oriented, and capable of managing multiple parallel projects within a fast-paced startup environment. Demonstrates a proactive, solution-driven mindset with a strong "can-do" attitude. Excellent communication, documentation, and interpersonal skills. Thrives in an interdisciplinary environment working alongside physicists, engineers, biologists, entrepreneurs, and senior executives Job Posted by ApplicantPro
    $55k-108k yearly est. 21d ago
  • Toxicologist

    Watton Hall

    Scientist job in Cambridge, MA

    Title: Toxicologist The Toxicologist will play a critical role in the assessment of the safety profile of small molecule drug candidates throughout the drug development process. This position requires a deep understanding of toxicological principles, regulatory requirements, and the ability to interpret complex data to inform decision-making. Responsibilities Conduct comprehensive toxicological evaluations of small molecules Analyze data from non-clinical studies to identify potential safety concerns and recommend strategies for risk mitigation. Prepare toxicology sections for regulatory submissions (INDs, NDAs) in accordance with FDA, EMA, and ICH guidelines. This will include liaising with the regulatory agencies related to toxicological data. Participate in project teams to provide expert advice on safety-related issues throughout the product lifecycle. Conduct risk assessments based on toxicological data to support decision-making processes regarding compound progression Profile Ph.D. or equivalent degree in Toxicology, Pharmacology, or a related field Mulitple years experience in the pharmaceutical or biotechnology industry. Small molecules experience Strong knowledge of GLP regulations, ICH guidelines, and FDA/EMA submission requirements. Experience working directly with regulatory agencies is an advantage. Benefits: Competitive salary with performance-based bonuses and comprehensive benefits package Home office option Excellent company culture
    $60k-101k yearly est. 60d+ ago
  • PHYSICAL SCIENTIST (ENVIRONMENTAL)

    Department of The Air Force

    Scientist job in Natick, MA

    The PALACE Acquire Program offers you a permanent position upon completion of your formal training plan. As a Palace Acquire Intern you will experience both personal and professional growth while dealing effectively and ethically with change, complexity, and problem solving. The program offers a 3-year formal training plan with yearly salary increases. Promotions and salary increases are based upon your successful performance and supervisory approval. Summary The PALACE Acquire Program offers you a permanent position upon completion of your formal training plan. As a Palace Acquire Intern you will experience both personal and professional growth while dealing effectively and ethically with change, complexity, and problem solving. The program offers a 3-year formal training plan with yearly salary increases. Promotions and salary increases are based upon your successful performance and supervisory approval. Overview Help Accepting applications Open & closing dates 09/29/2025 to 09/28/2026 Salary $49,960 to - $99,314 per year Total salary varies depending on location of position Pay scale & grade GS 7 - 9 Locations Gunter AFB, AL Few vacancies Maxwell AFB, AL Few vacancies Davis Monthan AFB, AZ Few vacancies Edwards AFB, CA Few vacancies Show morefewer locations (44) Los Angeles, CA Few vacancies Travis AFB, CA Few vacancies Vandenberg AFB, CA Few vacancies Air Force Academy, CO Few vacancies Buckley AFB, CO Few vacancies Cheyenne Mountain AFB, CO Few vacancies Peterson AFB, CO Few vacancies Schriever AFB, CO Few vacancies Joint Base Anacostia-Bolling, DC Few vacancies Cape Canaveral AFS, FL Few vacancies Eglin AFB, FL Few vacancies Hurlburt Field, FL Few vacancies MacDill AFB, FL Few vacancies Patrick AFB, FL Few vacancies Tyndall AFB, FL Few vacancies Robins AFB, GA Few vacancies Hickam AFB, HI Few vacancies Barksdale AFB, LA Few vacancies Hanscom AFB, MA Few vacancies Natick, MA Few vacancies Aberdeen Proving Ground, MD Few vacancies Andrews AFB, MD Few vacancies White Oak, MD Few vacancies Offutt AFB, NE Few vacancies Holloman AFB, NM Few vacancies Kirtland AFB, NM Few vacancies Nellis AFB, NV Few vacancies Rome, NY Few vacancies Heath, OH Few vacancies Wright-Patterson AFB, OH Few vacancies Tinker AFB, OK Few vacancies Arnold AFB, TN Few vacancies Dyess AFB, TX Few vacancies Fort Sam Houston, TX Few vacancies Goodfellow AFB, TX Few vacancies Lackland AFB, TX Few vacancies Randolph AFB, TX Few vacancies Hill AFB, UT Few vacancies Arlington, VA Few vacancies Dahlgren, VA Few vacancies Langley AFB, VA Few vacancies Pentagon, Arlington, VA Few vacancies Fairchild AFB, WA Few vacancies Warren AFB, WY Few vacancies Remote job No Telework eligible No Travel Required Occasional travel - You may be expected to travel for this position. Relocation expenses reimbursed No Appointment type Internships Work schedule Full-time Service Competitive Promotion potential 13 Job family (Series) * 1301 General Physical Science Supervisory status No Security clearance Secret Drug test No Position sensitivity and risk Noncritical-Sensitive (NCS)/Moderate Risk Trust determination process * Suitability/Fitness Financial disclosure No Bargaining unit status No Announcement number K-26-DHA-12804781-AKK Control number 846709200 This job is open to Help The public U.S. Citizens, Nationals or those who owe allegiance to the U.S. Students Current students enrolled in an accredited high school, college or graduate institution. Recent graduates Individuals who have graduated from an accredited educational institute or certificate program within the last 2 years or 6 years for Veterans. Clarification from the agency This public notice is to gather applications that may or may not result in a referral or selection. Duties Help * Performs continuing work assignments involving environmental physical science. Participates in and provides support to a variety of complex projects carried out by higher level staff; and carries out smaller projects involving moderate levels of complexity and consequences. * Responsible for carrying out assigned, well defined, moderate-sized projects or assigned portions of more complex projects, (in-house and by contract), to comply with all applicable Federal, state, and local environmental laws and policies. * Coordinates curricula and training for assigned program areas at the installation. Support quality improvement and promotes the environmental awareness program. * Provides advisory services on problems and issues relating to well defined, moderate-sized projects in assigned program areas. Requirements Help Conditions of employment * Direct Deposit: All federal employees are required to have direct deposit * Student Loan Repayment may be authorized * Please read this Public Notice in its entirety prior to submitting your application for consideration. * U.S. Citizenship is required * Males must be registered for Selective Service, see *********** * Total salary varies depending on location of position * Permanent Change of Station (PCS) expenses may or may not be authorized. PCS expenses if authorized will be paid IAW JTR and Air Force Regulations * Recruitment incentives may be authorized * Position may be subject to random drug testing * Employee must maintain current certifications * A security clearance may be required: secret, top secret, or special sensitive * Disclosure of Political Appointments * Mobility - you may be required to relocate during or after completion of your training * You will be required to serve a one year probationary period * Must meet suitability for Federal employment * Grade Point Average - 2.95 or higher out of a possible 4.0 * Successful completion of all training and regulatory requirements as identified in the applicable training plan * Work may occasionally require travel away from the normal duty station on military or commercial aircraft Qualifications BASIC REQUIREMENT OR INDIVIDUAL OCCUPATIONAL REQUIREMENT: Degree: physical science, engineering, or mathematics that included 24 semester hours in physical science and/or related engineering science such as mechanics, dynamics, properties of materials, and electronics. In addition to meeting the basic requirement above, to qualify for this position you must also meet the qualification requirements listed below: 1. GS-7: You must have completed or will complete a 4-year course of study leading to a bachelor's from an accredited institution AND must have documented Superior Academic Achievement (SAA) at the undergraduate level in the following: a) Grade Point Average 2.95 or higher out of a possible 4.0 as recorded on your official transcript or as computed based on 4 years of education or as computed based on courses completed during the final 2 years of curriculum; OR 3.45 or higher out of a possible 4.0 based on the average of the required courses completed in your major field or the required courses in your major field completed during the final 2 years of your curriculum. 2. GS-9: You must have completed 2 years of progressively higher-level graduate education leading to a master's degree or equivalent graduate degree: a) Grade Point Average - 2.95 or higher out of a possible 4.0 as recorded on your official transcript or as computed based on 4 years of education or as computed based on courses completed during the final 2 years of curriculum; OR 3.45 or higher out of a possible 4.0 based on the average of the required courses completed in your major field or the required courses in your major field completed during the final 2 years of your curriculum. If more than 10 percent of total undergraduate credit hours are non-graded, i.e. pass/fail, CLEP, CCAF, DANTES, military credit, etc. you cannot qualify based on GPA. KNOWLEDGE, SKILLS AND ABILITIES (KSAs): Your qualifications will be evaluated on the basis of your level of knowledge, skills, abilities and/or competencies in the following areas: 1. Professional knowledge of environmental physical science principles, practices, techniques, and procedures to carry out tasks and provide support using established procedures and methods in assigned. 2. Knowledge to perform a variety of technical tasks in support of projects assigned to higher level scientists or engineers using established technology to investigate unsanitary or questionable conditions in assigned. 3. Knowledge of applicable Federal, State, and local laws, regulations, and other guidance to use in applying to assigned tasks in the areas of restoration, compliance, conservation, pollution prevention, and/or integration principles and practices. 4. Ability to establish effective working relationships with others. 5. Ability to communicate effectively, both orally and in writing, clearly, concisely, and with technical accuracy. PART-TIME OR UNPAID EXPERIENCE: Credit will be given for appropriate unpaid and or part-time work. You must clearly identify the duties and responsibilities in each position held and the total number of hours per week. VOLUNTEER WORK EXPERIENCE: Refers to paid and unpaid experience, including volunteer work done through National Service Programs (i.e., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community; student and social). Volunteer work helps build critical competencies, knowledge and skills that can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience. Education IF USING EDUCATION TO QUALIFY: You MUST provide transcripts to support your educational claims. Education must be accredited by an accrediting institution recognized by the U.S. Department of Education. FOREIGN EDUCATION: Education completed in foreign colleges or universities may be used to meet the requirements. You must show proof the education credentials have been deemed to be at least equivalent to that gained in conventional U.S. education program. It is your responsibility to provide such evidence when applying. Additional information For DHA Positions: These positions are being filled under Direct-Hire Authority for the Department of Defense for Post-Secondary Students and Recent Graduates. The Secretary of the Air Force has delegated authority by the Office of the Secretary of Defense to directly appoint qualified post-secondary students and recent graduates directly into competitive service positions; these positions may be professional or administrative occupations and are located Air Force-Wide. Positions may be filled as permanent or term with a full-time or part-time work schedule. Pay will vary by geographic location. * The term "Current post-secondary student" means a person who is currently enrolled in, and in good academic standing at a full-time program at an institution of higher education; and is making satisfactory progress toward receipt of a baccalaureate or graduate degree; and has completed at least one year of the program. * The term "recent graduate" means a person who was awarded a degree by an institution of higher education not more than two years before the date of the appointment of such person, except in the case of a person who has completed a period of obligated service in a uniform service of more than four years. Selective Service: Males born after 12-31-59 must be registered or exempt from Selective Service. For additional information, click here. Direct Deposit: All federal employees are required to have direct deposit. If you are unable to apply online, view the following link for information regarding Alternate Application. The Vacancy ID is If you have questions regarding this announcement and have hearing or speech difficulties click here. Tax Law Impact for PCS: On 22-Dec-2017, Public Law 115-97 - the "Tax Cuts and Jobs Act of 2017" suspended qualified moving expense deductions along with the exclusion for employer reimbursements and payments of moving expenses effective 01-Jan-2018 for tax years 2018 through 2025. The law made taxable certain reimbursements and other payments, including driving mileage, airfare and lodging expenses, en-route travel to the new duty station, and temporary storage of those items. The Federal Travel Regulation Bulletin (FTR) 18-05 issued by General Services Administration (GSA) has authorized agencies to use the Withholding Tax Allowance (WTA) and Relocation Income Tax Allowance (RITA) to pay for "substantially all" of the increased tax liability resulting from the "2018 Tax Cuts and Jobs Act" for certain eligible individuals. For additional information on WTA/RITA allowances and eligibilities please click here. Subsequently, FTR Bulletin 20-04 issued by GSA, provides further information regarding NDAA FY2020, Public Law 116-92, and the expansion of eligibility beyond "transferred" for WTA/RITA allowances. For additional information, please click here. Expand Hide additional information Candidates should be committed to improving the efficiency of the Federal government, passionate about the ideals of our American republic, and committed to upholding the rule of law and the United States Constitution. Benefits Help A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new window Learn more about federal benefits. Review our benefits Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered. How you will be evaluated You will be evaluated for this job based on how well you meet the qualifications above. For DHA Positions: These positions are being filled under Direct-Hire Authority for the DoD for Post-Secondary Students and Recent Graduates. The Secretary of the Air Force has delegated authority by the Office of the Secretary of Defense to directly appoint qualified students and recent graduates directly into competitive service positions; positions may be professional or administrative occupations and located Air Force-Wide. Positions may be filled as permanent/term with a full-time/part-time work schedule. Pay will vary by geographic location. * The term "Current post-secondary student" means a person who is currently enrolled and in good academic standing at a full-time program at an institution of higher education; and is progressing toward a baccalaureate or graduate degree; and has completed at least 1 year of the program. * The term "recent graduate" means a person awarded a degree by an institution of higher education not more than 2 years before the date of the appointment of such person, except in the case of a person who has completed a period of obligated service in a uniform service of more than 4 years. Your latest resume will be used to determine your qualifications. Your application package (resume, supporting documents, and responses to the questionnaire) will be used to determine your eligibility, qualifications, and quality ranking for this position. Please follow all instructions carefully. Errors or omissions may affect your rating or consideration for employment. Your responses to the questionnaire may be compared to the documents you submit. The documents you submit must support your responses to the online questionnaire. If your application contradicts or does not support your questionnaire responses, you will receive a rating of "not qualified" or "insufficient information" and you will not receive further consideration for this job. Applicants who disqualify themselves will not be evaluated further. Benefits Help A career with the U.S. government provides employees with a comprehensive benefits package. As a federal employee, you and your family will have access to a range of benefits that are designed to make your federal career very rewarding. Opens in a new window Learn more about federal benefits. Review our benefits Eligibility for benefits depends on the type of position you hold and whether your position is full-time, part-time or intermittent. Contact the hiring agency for more information on the specific benefits offered. Required documents Required Documents Help The following documents are required and must be provided with your application for this Public Notice. Applicants who do not submit required documentation to determine eligibility and qualifications will be eliminated from consideration. Other documents may be required based on the eligibility/eligibilities you are claiming. Click here to view the AF Civilian Employment Eligibility Guide and the required documents you must submit to substantiate the eligibilities you are claiming. * Online Application - Questionnaire * Resume: Your resume may NOT exceed two pages, and the font size should not be smaller than 10 pts. You will not be considered for this vacancy if your resume is illegible/unreadable. Additional information on resume requirements can be located under "
    $50k-99.3k yearly 35d ago
  • Process Development Associate II

    Keros Therapeutics

    Scientist job in Lexington, MA

    This role is responsible for providing overall support in early stages of process development and acting as an interface with the Research and CMC organizations. The Scientist is responsible for projects focused on developing, optimizing, and scaling cell lines and fed-batch processes for biologics manufacturing and other applications. The Scientist will also be involved in tech transfer activities for external manufacturing. Primary Responsibilities: * Understanding of critical process parameters, and developing robust, industrial processes for cell culture production of protein derived from mammalian cell lines for cGMP implementation * Experience with and cell culture scale up/down and process characterization * Experience delivering material suitable for toxicology studies to support regulatory filings * Performing and and operation of protein expression including cell culture from microplate to , familiarity with cell banking, comprehension of manufacturing processes (specifically batch and fed-batch) and harvest of material at required scales * Data analysis and authoring key documents such as development reports * Participating in cross-functional project teams and communicating data, results, and conclusions to scientists, project management, business development, and other stakeholders. * Execute routine scale down protein expression using benchtop bioreactors to optimize protein expression processes * Perform, develop and optimize robust, efficient, scalable strategies for improving process performance * Activities will include small-scale studies and pilot scale expression studies * Apply DOE methods to expression activities * Mentoring Co-Ops and helping them in their planning and activities. * Maintain laboratory notebooks and digital records * Present data at process development and CMC department meetings Qualifications: * B.S. in Biology, Biochemistry, Biomedical Engineering, or an equivalent engineering/science degree with 2-5 years of experience working in the Biopharma industry * Strong hands-on experience in troubleshooting and routine instrument maintenance * Upstream processes at the small to an intermediate scale of cGMP biologics production * Process scaling and/or technology transfer * Authoring and executing protocols, interpretation of data, and report generation * Operating and troubleshooting process equipment * Ability to work independently and as part of a cross-functional team * Ability to adapt to frequent change and thrive in a dynamic early-stage environment * Strong communication and organization skills, strong knowledge of MS Office, data plotting and graphing software. Must be able to communicate results effectively. Experience using electronic lab notebooks preferred
    $59k-83k yearly est. Auto-Apply 2d ago
  • Pharmaceutical Physical Properties Scientist

    Eurofins Scientific 4.4company rating

    Scientist job in Groton, MA

    Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years. Job Description * Analysis of powder samples for key physical properties (such as particle size distribution, bulk density, true density, powder flow, particle shape) * Analysis of liquid samples for key physical properties (such as viscosity and surface tension) * Using techniques such as optical microscopy, laser diffraction particle size analysis, electron microscopy, shear cell testing, compaction simulation, etc. Qualifications * Bachelor's degree in chemistry or other science related degree concentration, or equivalent directly-related experience * At least one year experience in particle and powder characterization * Strong computer, scientific, and organizational skills * Proficient in learning new techniques, developing and carrying out experimental plans, and performing multiple tasks simultaneously * Experience in data handling and scientific/engineering computations * Excellent communication (oral and written) and attention to detail * Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude * Ability to keep accurate records, follow instructions, and comply with company policies * At least one year experience in particle and powder characterization Additional Information * Position is full-time, Monday - Friday 8am to 5 pm * Ability to work overtime as required. * Tasks require repetitive motion and standing for long periods of time. * May be required to respond to off-shift operational issues. * Candidates currently living within a commutable distance of Groton, CT are encouraged to apply. * Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options * Life and disability insurance * 401(k) with company match * Paid vacation and holidays * #LI-EB1 * Authorization to work in the United States indefinitely without restriction or sponsorship Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
    $56k-93k yearly est. 56d ago

Learn more about scientist jobs

How much does a scientist earn in Manchester, NH?

The average scientist in Manchester, NH earns between $53,000 and $108,000 annually. This compares to the national average scientist range of $67,000 to $140,000.

Average scientist salary in Manchester, NH

$76,000

What are the biggest employers of Scientists in Manchester, NH?

The biggest employers of Scientists in Manchester, NH are:
  1. GZA GeoEnvironmental
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