Senior principal scientist jobs in Babylon, NY

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team This position does not require you to be medical qualified. Demonstrates diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

About us ATG (Autonomous Technologies Group) is an AI lab deploying frontier reasoning systems within financial markets. Founders: Early GPU cloud (9 figure exit). Investors: Garry Tan / YC + Founder of one of the most successful quant funds, BoxGroup (Plaid, Ramp, Stripe), top-tier angels. About the Role You'll drive original research at the boundaries of AI, working on new models, algorithms, and architectures for reasoning in complex environments. Your work will shape the scientific agenda of the lab and inform everything we build. You'll have autonomy to pursue fundamental research and see your ideas deployed in real-world settings. Responsibilities Formulate and explore open questions in deep learning, reinforcement learning, and agent-based AI. Develop novel architectures, algorithms, and theoretical insights. Collaborate with engineers to implement, experiment, and iterate rapidly. Publish, present, and contribute to the broader research community. Mentor and support the next generation of technical talent. Requirements Demonstrated track record of impactful AI/ML research (e.g., papers, open-source, or novel deployments). Deep expertise in at least one of: LLMs, RL, agent-based systems, generative modeling, theory of intelligence. Strong mathematical background (probability, optimization, statistics). Proficiency in Python and modern ML frameworks (e.g., PyTorch, JAX). Ability to turn theory into robust, practical code. Up-to-date on the latest research in LLMs from reading papers, articles, or re-implementing breakthroughs. Expertise in leveraging the latest AI tools (Cursor, Claude Code, Codex, etc) to increase productivity & code output while maintaining high code quality, maintainability, and structure. Why Join ATG We're building a small, elite team. If you're excited by AI, markets, and building from first principles, we'd love to meet you. Work on AI with a massive market opportunity Early team of repeat founders backed by top investors High agency, talent dense, zero bureaucracy

COMPANY Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Our lead pipeline programs focus on two distinct inhibitors of KIF18A, a novel therapeutic target. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Volastra is also developing new techniques to understand the biology of chromosomal instability and leveraging these insights to drive forward a preclinical pipeline of therapies against innovative targets. Volastra is backed by top US and European venture firms such as Arch, Polaris, Vida, Droia, Catalio, and B Capital, alongside strategic investment from Eli Lilly. In addition to venture funding, Volastra has established partnerships with oncology leaders. Our senior leadership team is highly experienced, supported by a world-class advisory board. We are headquartered in West Harlem, New York City, within easy reach of Columbia, Cornell, Memorial Sloan Kettering, and surrounding areas. Please visit ****************** for more information. JOB DESCRIPTION: The role of Scientist of Discovery Science will report to the Senior Scientist/Senior Lab Manager in close collaboration with the Chief Scientific Officer and the rest of the Discovery Team, and work towards the successful execution of preclinical development programs. As a scientist, you will play a central role in turning foundational CIN biology into new medicines. You will design, execute, and interpret rigorous experiments that validate targets, elucidate mechanism of action, and accelerate progression from hit/lead to in vivo proof‑of‑concept. This is a bench‑forward position for a creative, self‑directed experimentalist who thrives in a fast‑moving biotech setting and loves collaborating across chemistry, biochemistry, DMPK, in vivo pharmacology, and computational biology. Volastra is a fast-paced biotech company of passionate employees, and there is ample opportunity for the ideal candidate to grow and develop with the organization. Individuals will have, from time to time, the opportunity to gain experience with projects outside their direct scope of work. Job is based in NYC and requires a minimum of 80% in office time. RESPONSIBILITIES: * Participate in key discovery workstreams from target validation through early pharmacology; design clear, decision‑driving experimental plans and timelines. * Interrogate mechanism using genetic perturbation (e.g. CRISPR/Cas9, RNAi), rescue, pathway mapping, and combination studies aligned with CIN biology. * Develop and optimize cellular assays to quantify phenotype and mechanism. * Build translationally relevant target‑engagement and PD assays to enable SAR and inform dose/PK-PD modeling for in vivo studies. * Track record of successfully managing external projects with CRO's from scoping to final data delivery * Work effectively with colleagues across the team to participate in adjacent discovery-related efforts * Provide clear updates to Discovery, Preclinical, and Leadership; write technical reports, support patent filings, and prepare data packages for milestones. REQUIREMENTS: * PhD in Molecular/Cell Biology, Biochemistry, Cancer Biology, Pharmacology or related field (or MS/BS with commensurate depth of industry experience). * 5+ years of hands-on lab experience with a range of relevant research techniques including cell-based assays and molecular biology. In vivo mouse experience is strongly preferred * Understanding of the drug development process from target identification to marketing authorization is strongly encouraged * Excellent communication, organizational, and problem-solving skills * Ability to collaborate well with team members PREFERRED EXPERIENCE: * Direct experience in CIN‑relevant biology (mitosis, microtubules/kinetochore function, replication stress, DNA‑damage response) or image‑based phenotyping * In vivo oncology familiarity (xenograft/PDX syngeneic models), PK/PD thinking, and translational biomarker awareness for discovery‑to‑development continuity. Salary Range: Approximately $130,000 - $150,000 which may vary depending on qualifications, experience, and ultimate leveling. Leveling outside of that stated may be considered for exceptional candidates on a case-by-case basis.

Immunai is an engineering-first platform company aiming to improve therapeutic decision-making throughout the drug discovery and development process. We are mapping the immune system at unprecedented scale and granularity and applying machine learning to this massive clinico-immune database, in order to generate novel insights into disease pathology for our partners - pharma companies and research institutes. We provide a comprehensive, end-to-end solution - from data generation and curation to therapeutics development, that continuously supports and validates the capabilities of our platform. As drug development is becoming increasingly inefficient, our ultimate goal is to help bring breakthrough medicines to patients as quickly and successfully as possible. Immunai is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. About the role: This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills. Location: New York City (On-site role) What will you do? * Augment efforts of teams using a wide range of techniques including, but not limited to immune cell isolation and processing from human specimens, cell cultures and in vitro model systems * Domain expert with single cell genomics methods, and proven experience of innovation in this field (sample optimization, protocol development). * Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware * Maintenance of a complete, accurate, and timely electronic record of all experiments using an informatics management system. * Active participation in cross-functional team meetings and effective communication with other members of the lab, computational biology, and software team * Expected to deliver impactful presentations to other colleagues including senior leadership Requirements Required qualifications: * 4-6 years of experience in Molecular Biology or Immunology; * MS with 2-4 years relevant experience, PhD with 1+ years of post-PhD experience is preferred. * Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes. Additionally, familiarity with high-throughput, automated single cell profiling workflows is preferred. * Experience working with tissue samples, including single cell dissociation. * Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage * Familiarity with high throughput lab data management (e.g. Benchling) * Strong analytical skills, problem solving ability, and innovation aptitude required * Must be willing to discover and learn new software and technology applications quickly * Must have strong attention to detail and an ability to multitask * Ability to collaborate closely with interdisciplinary individuals from a broad range of backgrounds * Ability to work independently with minimal supervision * Ability to work successfully in a fast-paced environment * Excellent interpersonal skills and ability to effectively work as part of a team are essential * Excellent organization and time management skills Desired personal traits: * You want to make an impact on humankind * You prioritize "We" over "I" * You enjoy getting things done and striving for excellence * You collaborate effectively with people of diverse backgrounds and cultures * You have a growth mindset * You are candid, authentic, and transparent Compensation: This position offers a salary typically between $105,000 - $140,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills. * Please note that when you apply for a position at Immunai, your application will be processed via our recruitment platform SparkHire. You can read more about how we process personal data here: ***************************************

JobID: 210688096 JobSchedule: Full time JobShift: Base Pay/Salary: New York,NY $137,750.00-$195,000.00 The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Scientist - Senior Associate on the AI Research team, you will conduct end-to-end research typically within a specialized focus area and collaborate on multiple research projects with internal and external researchers and applied engineering teams. Your output will result in high-impact business applications, open-source software, patents and/or publications in AI/ML conferences and journals. The goal of J.P. Morgan AI Research is to explore and advance cutting-edge research in AI, including ML as well as related fields like Cryptography, impacting clients and businesses, with a team of experts located in New York, London, Madrid, Paris, and the Bay Area. Conducting AI research in financial services offers unique and exciting opportunities for impact to both J.P. Morgan and the broader AI community. Job responsibilities * Conduct end-to-end research typically within Natural Language Processing (NLP) * Collaborate with internal and external researchers and with applied engineering teams * Engage in all aspects of the research lifecycle such as formulating problems, gathering data, generating hypotheses, developing models and algorithms, conducting experiments, synthesizing results, building prototype applications and communicating the significance of your research * Produce outputs that lead to high-impact business applications, open source software, patents and/or publications in top AI/ML conferences and journals * Participate in relevant top-tier academic conferences to broaden the impact of your contributions Required qualifications, capabilities, and skills * PhD in Computer Science or related field or a MS with at least 3 years of experience in the field * Research publications in prominent NLP venues; e.g., conferences, journals * Strong expertise in one or more specialized areas of relevance e.g., LLM-based reasoning, foundational models, multimodal document analytics, knowledge representation, natural language processing and understanding * Experience in NLP/ML platforms such as Tensorflow/Keras, PyTorch, AWS, Hugging Face, etc. * Proficiency with rapid prototyping and disciplined software development processes * Expertise in software engineering within collaborative project settings Preferred qualifications, capabilities, and skills * Extensive programming skills in Python, Java or C++ * Interest in problems related to the financial services domain (specific past experience in the domain is not required)

The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Scientist - Senior Associate on the AI Research team, you will conduct end-to-end research typically within a specialized focus area and collaborate on multiple research projects with internal and external researchers and applied engineering teams. Your output will result in high-impact business applications, open-source software, patents and/or publications in AI/ML conferences and journals. The goal of J.P. Morgan AI Research is to explore and advance cutting-edge research in AI, including ML as well as related fields like Cryptography, impacting clients and businesses, with a team of experts located in New York, London, Madrid, Paris, and the Bay Area. Conducting AI research in financial services offers unique and exciting opportunities for impact to both J.P. Morgan and the broader AI community. Job responsibilities Conduct end-to-end research typically within Agents, Reasoning (including AI heuristic search, planning, scheduling, constraint reasoning), Knowledge representation and Learning Collaborate with internal and external researchers and with applied engineering teams Engage in all aspects of the research lifecycle such as formulating problems, gathering data, generating hypotheses, developing models and algorithms, conducting experiments, synthesizing results, building prototype applications and communicating the significance of your research Produce outputs that lead to high-impact business applications, open source software, patents and/or publications in top AI/ML conferences and journals Participate in relevant top-tier academic conferences to broaden the impact of your contributions Required qualifications, capabilities, and skills PhD in Computer Science or related field or a MS in Computer Science or related field with at least 3 years of experience in the field Research publications in prominent AI venues; e.g., conferences, journals Expertise in one or more specialized areas of relevance e.g., heuristic search, planning, agent-based architectures, hybrid systems, knowledge representation, … Strong expertise in synthetic data, generative AI, differential privacy, uncertainty quantification, LLM alignment and behavior modeling using RL, bandit techniques, watermarking. time-series, reasoning and foundational models Proficiency with rapid prototyping and disciplined software development processes Expertise in software engineering within collaborative project settings Preferred qualifications, capabilities, and skills Extensive programming skills in Python (required), Java or C++ (optional) Interest in problems related to the financial services domain (specific past experience in the domain is not required)

Job Title: Scientist II- Immunology Anvia Therapeutics is a dynamic and innovative biotech company dedicated to developing small molecule inhibitors targeted at treating inflammatory and autoimmune diseases. We foster a collaborative environment where scientific excellence and creativity drive our mission to develop impactful medicines. Job Summary We are seeking a highly motivated immunology Scientist to drive hypothesis-driven in vitro immunology research in a fast-paced and innovative drug discovery environment. The successful candidate will design, develop, and execute complex cellular assay systems, including primary human immune cells, patient-derived samples, and disease-relevant cell lines to support immune pharmacology and mechanism-of-action (MoA) studies across inflammatory disease programs such as IBD, rheumatoid arthritis, and dermal inflammation. Responsibilities Key Responsibilities Design and execute hypothesis-driven cellular assays to support immune pharmacology, target validation, and MoA studies. Develop, optimize, and validate complex in vitro assay systems using primary immune cells, patient-derived samples, and disease-relevant or engineered cell lines. Perform functional immune assays including cell activation, proliferation, cytokine production, signaling, and cytotoxicity, using both primary and cell-line-based systems. Contribute to immune pharmacology assessments, including compound potency, pathway modulation, selectivity, and translational relevance. Apply a strong mechanistic understanding of immune and inflammatory signaling pathways to guide assay design and data interpretation. Utilize flow cytometry, ELISA/MSD/other cytokine/chemokine profiling techniques, protein- and signaling-based assays, and related techniques to generate high-quality, reproducible data. Analyze, interpret, and clearly communicate experimental results to project and leadership teams. Troubleshoot and refine experimental systems to improve robustness, scalability, and biological relevance. Maintain accurate experimental records using electronic laboratory notebooks. Collaborate closely with lead discovery, chemistry, translational, and external partners to advance program milestones. Stay current with emerging immunology technologies and incorporate innovative methodologies where appropriate. Qualifications Required Qualifications PhD in Immunology, Biology, Biotechnology, Molecular Biology, or a related field with 2+ years of relevant experience. Hands-on experience developing and executing complex cellular assays using primary immune cells, patient-derived samples, and cell line-based systems. Experience working with functional immune readouts, including flow cytometry-based phenotyping and signaling assays, and cytokine measurement (ELISA/MSD/other). Demonstrated expertise in protein-level analysis of signaling pathways, including Western blotting and related biochemical techniques used to assess pathway activation, inhibition, and mechanism of action. Strong understanding of cell signaling pathways relevant to immune and inflammatory biology. Proven ability to independently design experiments, troubleshoot assays, and manage multiple priorities. Proficiency with data analysis and visualization tools (e.g., GraphPad Prism, FlowJo, Excel). Excellent written and verbal communication skills. Preferred Qualifications Experience supporting immune pharmacology and MoA characterization in early drug discovery. Background in inflammatory or autoimmune disease biology (IBD, RA, dermatology preferred). Familiarity with assay validation, quantitative potency assessment and translational biomarker analysis/ identification. Experience working in a fast-paced, innovative biotech environment. Why Join Us? Be part of a passionate team making a difference in biotech innovation. Collaborative and dynamic work environment. Hands-on experience with state-of-the-art technologies. Opportunities for professional development and advancement. Competitive compensation and benefits. The salary range for this position is $115,000-$150,000 per year. The actual compensation offered will be based on factors such as relevant experience, education, and skills. In addition to base salary, we offer a comprehensive benefits package, including health insurance, paid time off, and retirement plan options. Anvia Therapeutics is an equal opportunity employer. We do not discriminate against any employee or applicant for employment because of race, creed (religion), color, national origin, sex (including gender identity and sexual orientation), age, disability, marital status, citizenship status, military status, genetic information, or any other characteristic protected by federal, state, or local law. Our employment decisions are based on merit, qualifications, and business needs. We are committed to providing a work environment free from discrimination, harassment, and retaliation, and we undertake affirmative action efforts to promote equal opportunity for all employees and applicants. #LI-DNI

Prime Video is a first-stop entertainment destination offering customers a vast collection of premium programming in one app available across thousands of devices. Prime members can customize their viewing experience and find their favorite movies, series, documentaries, and live sports - including Amazon MGM Studios-produced series and movies; licensed fan favorites; and programming from Prime Video add-on subscriptions such as Apple TV+, Max, Crunchyroll and MGM+. All customers, regardless of whether they have a Prime membership or not, can rent or buy titles via the Prime Video Store, and can enjoy even more content for free with ads. Are you interested in shaping the future of entertainment? Prime Video's technology teams are creating best-in-class digital video experience. As a Prime Video technologist, you'll have end-to-end ownership of the product, user experience, design, and technology required to deliver state-of-the-art experiences for our customers. You'll get to work on projects that are fast-paced, challenging, and varied. You'll also be able to experiment with new possibilities, take risks, and collaborate with remarkable people. We'll look for you to bring your diverse perspectives, ideas, and skill-sets to make Prime Video even better for our customers. With global opportunities for talented technologists, you can decide where a career Prime Video Tech takes you! For examples of our work, please see a selection of our publications from ECCV, ICCV and ICLR: • ********************************************************************************************************************************** • **************************************************************************** • ************************************************************************************************************************ Key job responsibilities As an Applied Scientist, your day-to-day responsibilities will include: Defining technical strategy: You will collaborate with other leaders in Prime Video to define the problem we will solve long-term to serve customers. You will formulate our science and engineering strategy for achieving this vision. Execution: You will be at the forefront in bring the strategy to life. You will directly deliver key components of our science and research roadmap. You will act as a force-multiplier for other scientists in the team. Developing Others: You will mentor and coach junior scientists in the team. You will drive scientific and technical best practices for others and elevate the quality of the output produced by the entire team. About the team Our Prime Video Content Understanding team builds holistic media representations (e.g. descriptions of scenes, semantic embeddings) and apply them to new customer experiences supply chain problems. Our technology spans the entire Prime Video catalogue globally, and we enable instant recaps, skip intro timing, ad placement, search, and content moderation. As an Applied Scientist in our Content Understanding Team, you will lead the end-to-end research and deployment of multi-modal models applied to a variety of downstream applications. We are seeking a science leader with deep knowledge of multi-modal content understanding, including Vision Language Models (VLMs) and Multi-Modal Language Models (MMLMs). - PhD, or Master's degree and 4+ years of CS, CE, ML or related field experience - 3+ years of building models for business application experience - Experience programming in Java, C++, Python or related language - Experience using Unix/Linux - Experience in professional software development Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $136,000/year in our lowest geographic market up to $223,400/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************** This position will remain posted until filled. Applicants should apply via our internal or external career site.

Teleskope is building the future of data security. Despite enormous growth in awareness and investment in data security, most companies still don't know where they are storing sensitive information and how to secure it. At Teleskope, we're building a modern and developer-friendly data security platform to automate data security and privacy at scale, from detection to remediation. About the role Teleskope is looking for an Applied NLP Scientist to play a critical role in the evolution of our remediation engine, which powers our data security and privacy platform. In this role, you will lead the development of agentic NLP systems that don't just detect risks in unstructured data but take proactive remediation and compliance actions directly within the Teleskope platform. You will design and build intelligent agents that operate across diverse enterprise data modalities (e.g., unstructured text, documents, tables, images), unifying extraction, prediction, and decision-making into action-oriented pipelines. This role involves working with massive datasets and building production-grade ML infrastructure that supports fast, reliable, and scalable inference for real-time remediation. This is a high-impact, in-office role based in NYC where you'll collaborate across engineering, product, and customer-facing teams to bring remediation-focused AI agents to life. What you'll do Own and evolve the Teleskope remediation and classification pipeline across multiple data modalities (e.g., text, documents, tables, images). Build and maintain agentic systems that unify information extraction with automated action-taking workflows. Apply modern NLP and LLM-based techniques for classification, clustering, summarization, and agent-driven decision-making. Define and build processes for evaluation, validation, and continuous monitoring of models and agents. Collaborate with product and engineering teams to integrate AI-driven remediation agents into customer-facing workflows. Stay on top of research and best practices in applied NLP, LLMs, and agentic architectures, contributing to the evolution of our ML stack. What you bring 4+ years of experience in applied NLP. Demonstrated success building and deploying LLM pipelines, agentic systems, or applied NLP models in production. Experience across the ML lifecycle: data preprocessing, model training, evaluation, and deployment. Bachelor's, Master's, or PhD in Computer Science, Computational Linguistics, or related field-or equivalent experience. Excellent communication and collaboration skills. Must be based in New York City-this is an in-office role. What you'll get An opportunity to join an early stage startup in one of today's fastest growing markets Space to build impactful features and own projects from start to finish Room to learn, grow, and rapidly advance in your data scientist career A beautiful, well-stocked office in NYC's Financial District Competitive salary and meaningful equity Health, vision, dental, 401k and more benefits, heavily subsidized by Teleskope What we value At Teleskope, we value technical excellence, practical execution, and a strong sense of ownership. We're looking for team members who bring domain expertise and a passion for shipping impactful ML solutions that meet real-world privacy and security needs.

Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the mission to reduce friction everywhere in healthcare. Our LLM-powered platform is solving chart review once and for all, across use cases. For health systems, our first product dramatically accelerates clinical registry abstraction in areas ranging from surgery and cardiology, to oncology. Our long term vision is for our AI layer to safely transform patient care and minimize unnecessary heartbreak. Layer Health's diverse founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We're seeking outstanding hires to join our team as early members. This is an opportunity to contribute to a high-impact, collaborative, mission-driven team, and help define the next stage of growth for Layer Health. Together, we will create the AI layer that will redefine healthcare for the better. Here's a collection of articles about our product, mission, recent funding round, etc. Job Description We're hiring an exceptional ML scientist. In this role, you will be responsible for pioneering innovative machine learning techniques to advance our fundamental clinical machine learning and large language model efforts. You can expect to: Design and implement state-of-the-art machine learning techniques to advance Layer Health's research agenda (in areas such as information extraction, multimodal reasoning, and summarization). Propose new agentic methods that tackle fundamental NLP and ML challenges such as modeling over multiple documents, long contexts, multiple modalities, and with limited or noisy labels Build foundation models to power the future of clinical information extraction & synthesis, from training through inference. Stay up-to-date and actively engage with cutting-edge research in NLP, generative AI, and clinical machine learning. Collaborate with the broader engineering team to ship performant products that meet user needs. Cultivate and foster a robust and thoughtful R&D culture that drives the company forward. We look for: Exceptional methodological research background and experience, including but not limited to: A PhD in computer science/applied mathematics or equivalent research experience, specializing in natural language processing and machine learning. High-impact, early-author publications at top peer-reviewed ML journals/conferences. Demonstrated record of delivering real-world impact from start to finish- with the ability to design, develop, and ship innovations. Strong programming skills and fluency with modern machine learning/LLM stacks (deep learning libraries e.g. PyTorch, Jax). Past experience in training/inference of foundation models (billions of parameters, distributed training, familiarity with state-of-the-art techniques). A strong communicator who thrives in a customer-focused, fast-paced environment. An excited and adaptable team player who wants to disrupt the healthcare industry with AI/ML, alongside an awesome team. Past experience in healthcare of life sciences is a plus, but not required. We are a Boston-based company, and expect employees to meet regularly in-person in Boston (employees from Boston, NYC, or east coast are welcome). Expected compensation range for this role is $200,000-250,000, in addition to stock options. Compensation is dependent on experience, overall fit to our role, and candidate location. Expected compensation ranges for this role may change over time. If your compensation requirement is greater than our posted salary ranges, please still consider applying to our role. We will make a determination as to whether an exception can be made. If you are excited about this role, we encourage you to apply even if you don't feel that you meet every single requirement. We're eager to meet people that believe in our mission and can contribute to our team in a variety of ways. We welcome diverse perspectives, rigorous thinking, and fearlessness in challenging the status quo. Layer Health is committed to fostering an environment of inclusion that is free from discrimination. We are an Equal Opportunity Employer where employment is decided on the basis of qualifications, merit, and business need. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected Veteran status, or any other characteristic protected by law. Join us and help us transform healthcare with AI.

Scientist II, Immuno-Oncology FUNCTIONAL AREA: REPORTS TO: Team Leader EXEMPT/NON-EXEMPT In the Immuno-Oncology team, we are looking for an enthusiastic, inventive and team-oriented scientist to join us in the creation cutting-edge cellular treatments for cancer and other serious diseases. We are looking for colleagues with a strong background in one or multiple areas including: Immuno-Oncology, Oncology or Immunology, and who possess strong expertise in T-cell biology, intricate multicolor flow cytometry, and in vivo mouse models. The ideal candidate would have a remarkable scientific record, excellent communication and interpersonal abilities, be passionate about scientific research, and excel at pushing boundaries for innovation. We value candidates who are adept at problem-solving and approach difficulties with optimism. The chosen individual will join a dynamic, creative and goal-oriented atmosphere dedicated to making impactful advances in the way we treat disease. Responsibilities Responsibilities include, but are not limited to: Develop innovative adoptive cell therapies to treat cancer or other serious diseases. Design, execute, and analyze in vitro experiments (some examples include engineering of CAR T-cells, cytotox, ELISA, proliferation assays, flow cytometry analysis, cell culture). Design, execute and analyze in vivo preclinical studies (some examples of procedures include tumor implantation, adoptive cell therapy administration, mice dosing through different administration routes, tumor monitoring, blood collection and multiple tissue analysis). Efficiently and clearly present and communicate scientific data to the team, cross-functionally and at external meetings. Pro-actively suggest and evaluate innovative cell engineering solutions and develop new assays to enhance the company's intellectual portfolio and contribute to peer-reviewed publications. Stay up to date with external scientific research from academic and industry institutions. Keep timely detailed documentation of experiments. Effectively plan and manage projects and deliverables to meet deadlines. Foster cross-functional collaborations and train other colleagues. Prioritize company objectives and work towards shared success. Other duties as necessary to ensure the daily operations of the lab and support the team. Core Competencies Keen eye for detail, exceptional problem-solving abilities, and a commitment to producing robust and high-quality scientific data for internal/external reports, publications and IND-enabling studies Strong scientific creativity and analytical thinking skills. Curiosity and drive to initiate and advance programs to treat diverse important diseases. Excellent written, oral and interpersonal communication skills. Capable of adhering to SOP and develop new protocols. Works well autonomously and collaboratively with other team members and cross-functionally. Flexibility and ability to adapt positively to a dynamic environment with changing priorities. Pro-active, transparent and adaptable team-player with a professional demeanor who works well under pressure. Comfortable operating in a fast-paced, small-midsized company environment. Requirements PhD in oncology, immunology, or equivalent (minimum of 3 years of experience after PhD in related role). Experience in human T-cell biology, immuno-oncology and knowledge in cell engineering technologies. Hands on experience and troubleshooting proficiency in immunology assays including immune cell isolation, multicolor flow cytometry, immune cell and cytokine profiling assays using conventional and next-generation analytical methods. Demonstrated experience designing and executing mouse tumor model experiments including mouse handling (injections- IV, SC, IP- and organ dissection). Excellent abilities to analyze and synthesize data for different audiences and report types while supporting decision-making processes. Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired. Basic knowledge of gene editing and next-generation sequencing technologies is a plus. Experience in working in matrixed environments and in project management is desired. Strong record of scientific publications and demonstrated scientific curiosity. Willingness to quickly adapt, innovate, discover new approaches, collaborate and support the team towards shared company goals. Candidates should be authorized to work in the U.S., preferably without the need for current, or future, sponsorship. Role is onsite and based in New York, NY Physical Requirements Sedentary - primarily involves sitting and/or standing. Laboratory work performed within a BSL1 and BSL2 environments. Communicates with others daily to exchange information. Salary Range (105,000 to 115,000 USD), dependent on skills and experience

Drug discovery is a prediction problem. Scientists design molecules that they predict will be potent, safe, and readily absorbed into the body, but ultimately lab experiments must be run to know whether these predictions are accurate. Each one of these experiments can take weeks or months to run, and as a result it costs millions of dollars and takes years to design a molecule that is ready for testing in humans. At Inductive Bio, we're using AI to build in silico models that can more accurately predict how molecules will behave in experiments. By predicting complex molecular properties directly from the molecular structure, our platform helps scientists make better decisions faster-ultimately bringing safer, higher-quality medicines to patients more quickly. We are enabled by a unique and growing proprietary data set, and we are already applying our methods to dozens of active drug discovery programs. Backed by leading investors at the intersection of biotechnology and technology and advised by renowned experts in drug discovery, we are growing rapidly and poised to make a major impact in drug discovery. We are seeking Machine Learning Scientists to join our talented, ambitious, and kind team. You'll have the opportunity to innovate on methods, work with leading drug discovery scientists, and apply your work immediately to drug programs at some of the most innovative biotechs in the world. As an early machine learning scientist at a rapidly-growing startup, you'll have the opportunity for high impact while learning and growing with the company. What you'll do: Develop machine learning models to predict molecular properties from chemical structures Develop novel algorithms for generating ideas for new molecules Build agents that can synthesize complex information from drug programs and apply that information strategically toward molecular optimization Get your hands dirty by diving deep into our unique, proprietary dataset to iterate on modeling ideas and improve model performance Collaborate closely with chemists and software engineers to integrate models into our software platform, which is used by drug discovery scientists across the industry Build and optimize scalable infrastructure for model training, deployment, and monitoring Engage directly with our scientific users, incorporating their feedback into the product Contribute meaningfully to product strategy and company direction Who you are: You have 4+ years of experience as a Machine Learning Scientist, Machine Learning Engineer, Data Scientist, or similar role You have expertise in machine learning fundamentals, deep learning architectures, and evaluation approaches You are proficient in standard Python-based ML frameworks (e.g. PyTorch, TensorFlow, scikit-learn) You are comfortable writing high-quality, reusable code and productionizing models for serving in the cloud You are excited to dive deep into the science and practice of drug discovery You have exceptional written and oral communication skills Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.

Biophysical Assoc Scientist needs 2+ years experience Biophysical Assoc Scientist requires: College degree in science related field or equivalent laboratory experience. Proficient MS Excel, Word, PowerPoint and File Explorer Ability to learn and develop comfort with various instrumentation software. Careful adherence to established procedures and proposed experimental design. Detail oriented and manual dexterity when working with instruments and samples. Demonstrating integrity in performing tasks to produce repeatable data. Excellent organizational and communication skills. Biophysical Assoc Scientist duties: Collects samples and prepares hair swatches to perform methods adhering to a set procedure. Performs technical procedures to measure product performance on hair with variety of lab equipment. Analyzes data, performs statistical calculations, and draws conclusions to substantiate claims.

R&D Partners is seeking to hire a Scientist Ops- 1st Shift in Branchburg, NJ. Your main responsibilities as a Scientist Ops- 1st Shift: The successful candidate will conduct non-routine laboratory experiments designed to implement new technologies or investigate basic scientific questions relevant to customer complaints/technical issues with Polymerase Chain Reaction (PCR) assays and reagents and project responsibilities. Designs, plans and executes assigned investigation/trouble shooting activities, research/development related experiments/projects and applying scientific knowledge and accumulated experience to complete projects. Need to accurately record information and make sound scientific interpretation of experimental results, which are to be communicated to non-scientific audience through investigational reports and verbal presentations. The successful candidate should have deductive reasoning and critical thinking in their tasks as they attempt to enact change to processes and reinforce new methodology in solving problems. Establish priorities, create and maintain time frames, and report status of project's progress toward established project goals and deadlines. What we are looking for in a Scientist Ops- 1st Shift: Bachelor s degree or equivalent combination of education and work experience in Biological science. 3 years of relevant industry experience or general laboratory experience. Why Choose R&D Partners? As an employee, you have access to a comprehensive benefits package including: Medical insurance PPO, HMO & HSA Dental & Vision insurance 401k plan Employee Assistance Program Long-term disability Weekly payroll Expense reimbursement Online timecard approval Pay Scale: $58,240 - $93,600 ( Dependent on Experience) R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal-opportunity employer.

You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within our Late-Stage Oncology portfolio. **Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate. Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams, governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s, analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings, seeks opportunities to further improve quality and efficiency of clinical procedures; PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in industry/CRO, **OR** MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in industry/CRO **OR** BA/BS in a relevant Science discipline and minimum of 10 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 2 - 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance Experience working on large data sets Proficiency with Microsoft Office and relevant scientific software Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations Experience building partnerships across the company to achieve the needs of the program **Demonstrates passion for helping patients with cancer and for the science of oncology Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. Work Location Assignment:** This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. **Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical

JobID: 210676234 JobSchedule: Full time JobShift: Base Pay/Salary: New York,NY $137,750.00-$195,000.00 The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Scientist Senior Associate in J.P. Morgan AI Research, you will work on novel techniques, tools, and frameworks to model and solve complex large-scale problems, collaborating with experts in AI Agents and contributing to high-impact business applications and the broader AI community. Your role involves formulating problems, generating hypotheses, developing algorithms and models, conducting experiments, and communicating research significance. Your output will result in publications, high-impact business applications, open-source software, and patents. Job responsibilities * Work on multiple research projects in collaboration with internal and external researchers and applied engineering teams * Formulate problems, generate hypotheses, develop new algorithms and models, conduct experiments, synthesize results, gather data, build prototypes, and communicate research significance * Contribute to publications in AI/ML conferences and journals, high-impact business applications, open-source software, and patents * Participate in relevant top-tier academic conferences, organize workshops, and engage with the AI research community to broaden the impact of your contributions Required qualifications, capabilities, and skills * PhD in Computer Science, Statistics, Engineering, or related fields * Programming skills in Python * Proficient understanding of fundamental AI and ML techniques (e.g., A*, regularization) * Practical experience with statistical data analysis and experimental design * Curiosity, creativity, resourcefulness, and a collaborative spirit * Effective verbal and written communication skills with technical and business audiences * Demonstrated ability to work on multi-disciplinary teams with diverse backgrounds * Interest in problems related to the financial services domain Preferred qualifications, capabilities, and skills * Research publications in prominent AI/ML or Software Engineering venues (e.g., conferences, journals) * Strong expertise in specialized areas such as deep learning (DL) or AI Agents * Practical experience with ML platforms such as TensorFlow/Keras, PyTorch * Comfort with rapid prototyping and disciplined software development processes * Practical software engineering experience in collaborative project settings * Hands-on experience developing and using AI Agents in a professional setting

The Applied Innovation of AI (AI2) team is an elite machine learning group strategically located within the Chief Technology Office of JP Morgan Chase. AI2 tackle business critical priorities using innovative machine learning techniques and technologies with a focus on machine learning for Software, Cybersecurity and Technology Infrastructure. The team partners closely with stakeholders in these areas to execute projects that require machine learning development to support JPMC businesses as they grow. Strategically positioned in the Chief Technology Office, our work spans across Cybersecurity, Global Technology Infrastructure and the Software Development Lifecycle (SDLC). With this unparalleled access to technology groups in the firm, the role offers a unique opportunity to explore novel and complex challenges that could profoundly transform how the bank operates. As a Machine Learning Scientist, you will apply sophisticated machine learning methods to a wide variety of complex tasks including data mining and exploratory data analysis and visualisation, text understanding and embedding, anomaly detection in time series and log data, large language models (LLMs) and generative AI for technology use-cases, reinforcement learning and recommendation systems. You must excel in working in a highly collaborative environment together with the business, technologists and control partners to deploy solutions into production. You must also have a passion for machine learning and invest independent time towards learning, researching and experimenting with new innovations in the field. You must have solid expertise in Deep Learning with hands-on implementation experience and possess strong analytical thinking, a deep desire to learn and be highly motivated. Job Responsibilities Research and explore new machine learning methods through independent study, attending industry-leading conferences and experimentation Develop state-of-the art machine learning models to solve real-world problems and apply it to complex business critical problems in Cybersecurity, Software and Technology Infrastructure Collaborate with multiple partner teams in Cybersecurity, Software and Technology Infrastructure to deploy solutions into production Drive firmwide initiatives by developing large-scale frameworks to accelerate the application of machine learning models across different areas of the business Contribute to reusable code and components that are shared internally and also externally Required qualifications, capabilities and skills PhD in a quantitative discipline (e.g. Computer Science, Electrical Engineering, Mathematics, Operations Research, Optimization, or Data Science.) with 1 year experience Or Masters with 2 years of industry or research experience in the field. Hands-on experience and solid understanding of machine learning and deep learning methods Extensive experience with machine learning and deep learning toolkits (e.g.: TensorFlow, PyTorch, NumPy, Scikit-Learn, Pandas) Extensive experience with large language models (LLMs) and accompanying tools & techniques in the LLM ecosystem (e.g. LangChain, LangGraph, Vector databases, opensource Models, RAG, Agentic Systems & Workflows, LLM fine-tuning) Scientific thinking and the ability to invent Ability to design experiments and training frameworks, and to outline and evaluate intrinsic and extrinsic metrics for model performance aligned with business goals Experience with big data and scalable model training Solid written and spoken communication to effectively communicate technical concepts and results to both technical and business audiences Curious, hardworking and detail-oriented, and motivated by complex analytical problems Ability to work both independently and in highly collaborative team environments Preferred qualifications, capabilities and skills Strong background in Mathematics and Statistics Familiarity with the financial services industries Experience with A/B experimentation and data/metric-driven product development Experience with cloud-native deployment in a large scale distributed environment Published research in areas of Machine Learning, Deep Learning or Reinforcement Learning at a major conference or journal Ability to develop and debug production-quality code Familiarity with continuous integration models and unit test development

At Inductive Bio we're tackling the challenge of making drug discovery more efficient. Chemists spend countless hours combining data, expertise, and intuition to create new molecules that are effective, safe, and work well in the human body. It's a slow, complex process, and the patients are the ones left waiting. At Inductive Bio, we're building an intuitive, collaborative platform, powered by state-of-the-art AI to help accelerate this process. Our platform is already being used on dozens of active drug discovery programs, and adoption is rapidly growing. We are backed by leading investors at the intersection of technology and biotechnology, and our team includes world-class technology and drug discovery experts. After achieving quick adoption via word-of-mouth, we are now expanding our capabilities to build state-of-the-art in silico models for toxicity prediction. We are seeking a senior Toxicologist to serve as our primary subject matter expert in toxicology, with an initial focus on liver and cardiac safety. In this role, you will help shape our scientific offering, ensure that our models are rigorously validated, and guide us toward solutions that have meaningful impact in real-world drug discovery programs. What you'll do: Serve as Inductive Bio's lead subject matter expert in toxicology, with a focus on liver and cardiac safety Guide the development of in silico toxicity models, ensuring scientific rigor, biological relevance, and translational utility Provide toxicology consulting support for partner programs Define the scientific standards, benchmarks, and validation approaches that underpin our toxicology offerings Collaborate with internal machine learning and chemistry experts to translate toxicological principles into predictive models Provide expert input into customer engagements, building credibility and helping to shape solutions tailored to partner needs Stay current on the evolving regulatory, scientific, and technological landscape in preclinical toxicology, bringing insights back to the team Contribute to external scientific presence, including publications, presentations, and conference participation Who you are: PhD in toxicology, pharmacology, or a closely related discipline 15+ years of experience in drug discovery or development with deep expertise in toxicology (preferably in both preclinical and translational contexts) Strong expertise in hepatotoxicity and cardiotoxicity, with familiarity across additional organ systems a plus Proven track record of applying toxicology insights to support decision-making in drug discovery or development programs Excellent communication and presentation skills, with the ability to explain complex concepts to both scientific and non-scientific audiences Experience interacting with regulatory authorities and knowledge of FDA/EMA/ICH guidance a strong plus Collaborative, pragmatic, and entrepreneurial-comfortable working across disciplines in a fast-moving startup environment Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast-growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical