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  • Sr. Applied Scientist, Prime Video - Personalization and Discovery Science

    Amazon 4.7company rating

    Senior principal scientist job in New York, NY

    Prime Video is a first-stop entertainment destination offering customers a vast collection of premium programming in one app available across thousands of devices. Prime members can customize their viewing experience and find their favorite movies, series, documentaries, and live sports - including Amazon MGM Studios-produced series and movies; licensed fan favorites; and programming from Prime Video add-on subscriptions such as Apple TV+, Max, Crunchyroll and MGM+. All customers, regardless of whether they have a Prime membership or not, can rent or buy titles via the Prime Video Store, and can enjoy even more content for free with ads. Are you interested in shaping the future of entertainment? Prime Video's technology teams are creating best-in-class digital video experience. As a Prime Video technologist, you'll have end-to-end ownership of the product, user experience, design, and technology required to deliver state-of-the-art experiences for our customers. You'll get to work on projects that are fast-paced, challenging, and varied. You'll also be able to experiment with new possibilities, take risks, and collaborate with remarkable people. We'll look for you to bring your diverse perspectives, ideas, and skill-sets to make Prime Video even better for our customers. With global opportunities for talented technologists, you can decide where a career Prime Video Tech takes you! We are looking for a self-motivated, passionate and resourceful Applied Scientist to bring diverse perspectives, ideas, and skill-sets to make Prime Video even better for our customers. You will spend your time as a hands-on machine learning practitioner and a research leader. You will play a key role on the team, building and guiding machine learning models from the ground up. At the end of the day, you will have the reward of seeing your contributions benefit millions of Amazon.com customers worldwide. Key job responsibilities - Develop AI solutions for various Prime Video Search systems using Deep learning, GenAI, Reinforcement Learning, and optimization methods; - Work closely with engineers and product managers to design, implement and launch AI solutions end-to-end; - Design and conduct offline and online (A/B) experiments to evaluate proposed solutions based on in-depth data analyses; - Effectively communicate technical and non-technical ideas with teammates and stakeholders; - Stay up-to-date with advancements and the latest modeling techniques in the field; - Publish your research findings in top conferences and journals. About the team Prime Video Search Science team owns science solution to power search experience on various devices, from sourcing, relevance, ranking, to name a few. We work closely with the engineering teams to launch our solutions in production. Basic Qualifications - PhD, or Master's degree and 6+ years of applied research experience - 5+ years of building machine learning models for business application experience - Experience programming in Java, C++, Python or related language Preferred Qualifications - Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc. - Experience with large scale distributed systems such as Hadoop, Spark etc. Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $150,400/year in our lowest geographic market up to $260,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************* . This position will remain posted until filled. Applicants should apply via our internal or external career site.
    $150.4k-260k yearly 8d ago
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  • Principal Research Scientist, Electromagnetism

    Arena Ai

    Senior principal scientist job in New York, NY

    New York or San Francisco Who we are: Our name is inspired by Theodore Roosevelt's ‘Citizenship in a Republic' speech, which pays homage to the ‘(hu)man in the Arena'. To us, entering the Arena means committing oneself fully and accepting the risk of failure in the pursuit of an audacious, worthy cause. We're a close-knit team of scientists and builders redefining the future of hardware engineering. If you share our passion for delving deep into real-world problems and solving them with fully autonomous AI, join us in the Arena. What we do: Our collective future is being built in the physical world, but the builders of tomorrow's technology can no longer rely on yesterday's tools. At Arena, we're building the world's first AI industrial engineer designed to solve the most complex hardware and manufacturing challenges. Our product, Atlas, is built with an understanding of the behavior of physical systems, powered by a superior knowledge of core domains of physics. Paired with its ability to reason about multimodal industrial data, Atlas can test, debug, optimize, and repair physical systems and products in the real world. Arena is already trusted by some of the most advanced industrial companies in the world (AMD, Bausch & Lomb), and we\u2019re rapidly already scaling into the defense, automotive, and aerospace industries, and we're just getting started. About the role: As a Principal Research Scientist, Electromagnetism, you will lead the architecture, training, and validation of our electromagnetic foundation model, bridging numerically solved physics equations, neural operators, and product-grade simulation. How you will contribute: Design FNO/AFNO/Deformation-FNO/U-FNO multiscale operator architectures with embedded physical constraints Implement causality/passivity enforcement and uncertainty calibration Proprietary Training Data Corpora Specify coverage targets Work with Arena's Platform Engineering team to orchestrate solver farms and synthetic generation Work with Arena Electrical Engineers to define a set of requirements and interface for physically-generated training data via hardware-in-the-loop test campaigns Develop sim-to-real calibration using for example VNA/near-field/BER measurements Evaluation & Validation Build automated accuracy and constraint eval suite Own releases and reporting Optimization & Performance Profile inference latency and throughput Leadership & Documentation Author design docs, experiments, and technical reports Qualifications You have: PhD or equivalent research track in Electrical Engineering, Applied Physics, Computer Science, or Applied Math Proven expertise building and training large foundation models Experience with FNO and/or Neural Operators Understanding of EM solvers (FEM/FDTD/MoM) Strong Python, PyTorch/JAX, C/C++ for bindings Proven record of physics-constrained ML or scientific simulation deployment [Preferred] Prior work on passivity/causality enforcement in learned models [Preferred] Familiar with PDN, high-speed channel design, and EMI compliance testing [Preferred] Experience and familiarity with high performance principles (e.g. Slurm for scheduling, message passing workloads, etc.), and cloud service provider HPC ecosystems (e.g. AWS Batch, Elastic Fabric Adapter, etc.) 100% of the monthly premium for Aetna medical insurance, plus vision and dental coverage 401(k) Retirement Plan Unlimited PTO Lunch every day from local restaurants via Sharebite Relocation support provided (NYC or SF) Benefits Salary: The base salary range for this position is $250,000 - $350,000 yr. However, base pay offered may vary depending on job-related knowledge, skills, and experience. In addition to base salary, we also offer competitive equity and benefits packages. Additional benefits: relocation support, health insurance options, and retirement plan offerings as listed above. #J-18808-Ljbffr
    $81k-117k yearly est. 1d ago
  • Analytical Scientist

    Astrix 4.1company rating

    Senior principal scientist job in Middlesex, NJ

    We are seeking an Analytical Scientist to join a reputable pharmaceutical manufacturing company to conduct routine and non-routine analyses of in-process materials, raw materials, environmental samples, finished goods, or stability samples. ** No Relocation, No C2C Candidates** Pay: Up to $45/hour. RESPONSIBILITIES: Conduct and document chemical analyses for raw materials, in-process goods, and finished products. Design, validate, and resolve issues with analytical methods, including HPLC for cleaning verification. Collect and analyze equipment cleaning validation samples. Prepare Certificates of Analysis, analytical reports, and maintain lab documentation. Peer-review records and support OOS or OOT investigations as per SOPs. Ensure compliance with SOPs, cGMPs, and regulatory requirements. Assist with environmental monitoring and other tasks as assigned. QUALIFICATIONS: 2 years hands-on method development experience (HPLC) Knowledge of cGMPs, pharmacopeia (USP, EP), and regulatory standards (21 CFR Part 210/211/820, ISO). Bachelor's in Chemistry-related discipline with 2+ years of analytical lab experience. This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!
    $45 hourly 3d ago
  • Staff Scientist / Grant Writer, Sanjana Lab

    New York Genome Center 4.5company rating

    Senior principal scientist job in New York, NY

    The Staff Scientist will prepare grant applications and other scientific communication materials on a wide range of genomic research topics. This role is deeply immersed in the science of NYGC and supports our research team in building and expanding a successful, independently-funded research base. They collaborate with diverse teams of students, postdoctoral fellows, and principal investigators, and relates scientific and strategic goals to individual grant opportunities and other research communications vehicles. Typical grants include individual investigator, multi-PI and research center grants. Key Responsibilities Takes a lead role in preparation and project management of individual and multi-investigator proposals; Provides advice on grantsmanship, editorial support and standardized language for administrative sections; Identifies opportunities for funding Manages the scientific writing process, including proposal management, team-building and coordination; establishing timelines and deliverables; Provides draft preparation, review and revision of grants and scientific writing. Coordinates with and supports Sponsored Research staff to ensure timely, accurate application submission. Edits manuscripts, fellowship applications, research progress reports, clinical research protocols and other research communications materials. Interacts with lab members to independently develop new grant proposals. Organizes small group meetings with lab members to review project progress, plan experiments, and integrate team data. Assists in the design and planning of functional genomics and genetic perturbation experiments; and, Assists in analysis and figure preparation of diverse types of data, including high-throughput sequencing, microscopy images, gel images, and schematic diagrams. Key Responsibilities include (but are not limited to): PhD in genetics, genomics, cancer biology, neuroscience or related discipline required; 5+ years research experience, including contributing to grant writing, required. NIH experience strongly desirable; Exceptional written communication skills required to prepare and edit competitive grant applications, publications, administrative materials, and other research communications; Ability to grasp complicated technical subjects, synthesize diverse lines of evidence and apply these abilities to technical writing required; Experience handling the scientific writing and project management process for multi-investigator and institutional grant applications strongly preferred; Experience with standard grant development concepts, practices, and procedures in a research environment preferred; Applied statistics background required, to perform power calculations and develop quantitative metrics for genomic assays; Ability to collaborate with diverse teams of investigators and administrative personnel required; and, Strong project management skills and experience required. Competencies Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations, and delivers on commitments. Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. Salary The salary range for this position is $62,000-78,000 per year. Base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer's, Parkinson's, Huntington's), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity We are committed to fostering a workplace environment that is welcoming and fair to all, ensuring that every employee has the opportunity to thrive. We believe that bringing together individuals with diverse backgrounds, experiences, and perspectives leads to greater collaboration, innovation, and discovery. Valuing and supporting each employee in reaching their full potential strengthens our organization and enhances our collective success. We recognize that creating an environment where all employees feel valued and included requires sustained effort and dedication from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are protected veterans and individuals with disabilities. FLSA Status - Exempt This position is eligible for visa sponsorship and relocation assistance.
    $62k-78k yearly 2d ago
  • Scientist - Cell-Based Assays

    Talent Software Services 3.6company rating

    Senior principal scientist job in Rahway, NJ

    Are you an experienced Scientist - Cell-Based Assays with a desire to excel? If so, then Talent Software Services may have the job for you! Our client is seeking an experienced Scientist - Cell-Based Assays to work at their company in Rahway, NJ. Position Summary: We're seeking a hands-on scientist to execute high-throughput cell-based assays in 384-well format. You will culture and plate cells, dispense compounds using the Echo, run diverse detection readouts, and analyze dose-response data to deliver high-quality EC50 results for discovery programs. Primary Responsibilities/Accountabilities: Maintain, expand, and plate mammalian cell lines for 384-well assays Set up and execute assays with compound dispensing via Labcyte/Beckman Echo Run and optimize detection formats (e.g., luminescence, cAMP, HTRF/TR-FRET, fluorescence) Generate dose-response curves (4-parameter logistic fits) and report EC50/IC50 with QC Troubleshoot assay performance, optimize Z' factors, and document SOPs/results Collaborate with discovery teams to prioritize studies and timelines Additional responsibilities may include setting up Western blot assays and learning how to run in-cell westerns Qualifications: BS/MS/PHD in Biology, Pharmacology, Biochemistry, or related field; BS with 5+ years, Masters with 3+ years and PHD with 1+ year of industry or equivalent lab experience. Proficiency in mammalian cell culture and 384-well assay workflows Experience with plate readers and assay platforms (e.g., cAMP, HTRF, luminescent assays) Strong data analysis skills: 4PL curve fitting, EC50/IC50 determination, and curve QC (e.g., R^2, top/bottom constraints) Detail-oriented, organized, and comfortable in a fast-paced, high-throughput environment Preferred: Experience with automation/LIQ handlers, LIMS/ELN, and statistical QC (Z', CV, S/B) Familiarity with GraphPad Prism, ActivityBase, or equivalent analysis tools Hands-on experience with Echo acoustic dispensing.
    $64k-104k yearly est. 4d ago
  • Postdoctoral Researcher, Experimental Solid Mechanics

    The American Ceramic Society 3.7company rating

    Senior principal scientist job in New York, NY

    A leading educational institution in New York is seeking a highly motivated Postdoctoral Researcher to contribute to advanced research in Experimental Solid Mechanics. The successful candidate will investigate material behavior under dynamic loading conditions and utilize advanced experimental techniques. A Ph.D. in relevant fields is preferred, along with strong problem-solving and communication skills. This role offers an exciting opportunity for collaboration in multidisciplinary teams. #J-18808-Ljbffr
    $51k-73k yearly est. 4d ago
  • Director of CAR-T Cell Therapy

    Astera Cancer Care 4.0company rating

    Senior principal scientist job in East Brunswick, NJ

    Astera Cancer Care East Brunswick/Monroe, NJ Job Details: Occupation: Physician Specialty: Hematology Employment: Full-Time Opportunity: Private Practice, Outpatient/Inpatient Board Certifications: BC Degree: MD/DO Ideal Candidate: Early to mid-career clinical researcher with a strong background in providing direct patient care and conducting clinical research in CAR-T Cell Therapy Leadership opportunity for someone who is passionate about advancing cutting-edge cellular therapies in oncology About the Role: Astera Cancer Care is seeking a Director of CAR-T Cell Therapy to conduct clinical research and manage patients. This includes overseeing patient selection, treatment planning, and post-infusion care to ensure optimal outcomes. The Director will lead a multidisciplinary team of nurses, pharmacists, and coordinators, fostering collaboration across all aspects of care delivery. In addition to clinical responsibilities, the role balances strategic oversight with program development, quality assurance, and operational planning. About the Area: East Brunswick, New Jersey, offers a family-friendly suburban lifestyle with top-rated public schools, diverse communities, and convenient access to New York City and Philadelphia via major highways and public transit. Residents enjoy a mix of green spaces, parks, and recreational amenities like Crystal Springs Waterpark, along with a variety of shopping and dining options. The area is known for its safety and cultural richness, making it an attractive place for families and professionals. Recruitment Package: Top-Tier Compensation: Benefit from highly competitive compensation structures. No cap on earning potential. Exact compensation may vary based on skills, experience, and location. Professional Growth: Enjoy CME reimbursement to further your education and skills. Comprehensive Benefits: Full employee benefits include: Medical, Dental, Vision, Short-Term and Long-Term Disability, Life, and Accidental Death. Secure Future: Robust retirement savings plan. Peace of Mind: We cover your malpractice insurance. Future Stability: Partnership opportunity offered. Work-Life Balance: Paid time off, to ensure you maintain a healthy work-life balance. Community Care: Make a real difference by caring for patients in their local communities. Career Advancement: Seize leadership opportunities for career growth within our organization. Innovative Research: Enroll patients in cutting-edge clinical trials. Academic Excellence: Present and participate in research at prestigious conferences. Supportive Environment: Join a physician-led and managed organization that values clinical autonomy, work-life balance, and quality patient care while prioritizing your professional development and well-being. About the Practice and their Mission: Astera Cancer Care is a physician-owned multi-specialty community oncology practice delivering high-quality, coordinated, patient-centered cancer care. At Astera Cancer Care, their mission is to transform cancer care and the care and management of blood disorders with patient-focused, research-based treatment guided by compassion. Their team of multidisciplinary experts works together to improve the patient experience and provide efficient access to care, minimizing the clinical, financial, and emotional barriers that patients face. The practice offers Hematology/Medical Oncology, Breast Surgery, Palliative Care, Radiation Oncology, and Clinical Trials & Research Programs. Astera Cancer Care is a proud partner of OneOncology. OneOncology is a national partnership of leading independent community oncology practices working together to improve the lives of everyone living with cancer with a physician-led, data-driven, technology-powered, and patient-centric model. Through OneOncology, partner practices have shared technology platforms that foster communication, data sharing, and clinical excellence across the network. OneOncology's non-exclusive clinical trial site management subsidiary, OneR, delivers complex, multi-center clinical trials to affiliated practices. If you would like to apply or learn more about this opportunity, please email your CV to ****************************** I look forward to speaking with you!
    $65k-84k yearly est. 1d ago
  • Scientist, Discovery Science

    Volastra

    Senior principal scientist job in New York, NY

    COMPANY Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Our lead pipeline programs focus on two distinct inhibitors of KIF18A, a novel therapeutic target. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Volastra is also developing new techniques to understand the biology of chromosomal instability and leveraging these insights to drive forward a preclinical pipeline of therapies against innovative targets. Volastra is backed by top US and European venture firms such as Arch, Polaris, Vida, Droia, Catalio, and B Capital, alongside strategic investment from Eli Lilly. In addition to venture funding, Volastra has established partnerships with oncology leaders. Our senior leadership team is highly experienced, supported by a world-class advisory board. We are headquartered in West Harlem, New York City, within easy reach of Columbia, Cornell, Memorial Sloan Kettering, and surrounding areas. Please visit ****************** for more information. JOB DESCRIPTION: The role of Scientist of Discovery Science will report to the Senior Scientist/Senior Lab Manager in close collaboration with the Chief Scientific Officer and the rest of the Discovery Team, and work towards the successful execution of preclinical development programs. As a scientist, you will play a central role in turning foundational CIN biology into new medicines. You will design, execute, and interpret rigorous experiments that validate targets, elucidate mechanism of action, and accelerate progression from hit/lead to in vivo proof‑of‑concept. This is a bench‑forward position for a creative, self‑directed experimentalist who thrives in a fast‑moving biotech setting and loves collaborating across chemistry, biochemistry, DMPK, in vivo pharmacology, and computational biology. Volastra is a fast-paced biotech company of passionate employees, and there is ample opportunity for the ideal candidate to grow and develop with the organization. Individuals will have, from time to time, the opportunity to gain experience with projects outside their direct scope of work. Job is based in NYC and requires a minimum of 80% in office time. RESPONSIBILITIES: * Participate in key discovery workstreams from target validation through early pharmacology; design clear, decision‑driving experimental plans and timelines. * Interrogate mechanism using genetic perturbation (e.g. CRISPR/Cas9, RNAi), rescue, pathway mapping, and combination studies aligned with CIN biology. * Develop and optimize cellular assays to quantify phenotype and mechanism. * Build translationally relevant target‑engagement and PD assays to enable SAR and inform dose/PK-PD modeling for in vivo studies. * Track record of successfully managing external projects with CRO's from scoping to final data delivery * Work effectively with colleagues across the team to participate in adjacent discovery-related efforts * Provide clear updates to Discovery, Preclinical, and Leadership; write technical reports, support patent filings, and prepare data packages for milestones. REQUIREMENTS: * PhD in Molecular/Cell Biology, Biochemistry, Cancer Biology, Pharmacology or related field (or MS/BS with commensurate depth of industry experience). * 5+ years of hands-on lab experience with a range of relevant research techniques including cell-based assays and molecular biology. In vivo mouse experience is strongly preferred * Understanding of the drug development process from target identification to marketing authorization is strongly encouraged * Excellent communication, organizational, and problem-solving skills * Ability to collaborate well with team members PREFERRED EXPERIENCE: * Direct experience in CIN‑relevant biology (mitosis, microtubules/kinetochore function, replication stress, DNA‑damage response) or image‑based phenotyping * In vivo oncology familiarity (xenograft/PDX syngeneic models), PK/PD thinking, and translational biomarker awareness for discovery‑to‑development continuity. Salary Range: Approximately $130,000 - $150,000 which may vary depending on qualifications, experience, and ultimate leveling. Leveling outside of that stated may be considered for exceptional candidates on a case-by-case basis.
    $130k-150k yearly Auto-Apply 59d ago
  • Scientist, Molecular Profiling

    Immunai 4.0company rating

    Senior principal scientist job in New York, NY

    Immunai is an engineering-first platform company aiming to improve therapeutic decision-making throughout the drug discovery and development process. We are mapping the immune system at unprecedented scale and granularity and applying machine learning to this massive clinico-immune database, in order to generate novel insights into disease pathology for our partners - pharma companies and research institutes. We provide a comprehensive, end-to-end solution - from data generation and curation to therapeutics development, that continuously supports and validates the capabilities of our platform. As drug development is becoming increasingly inefficient, our ultimate goal is to help bring breakthrough medicines to patients as quickly and successfully as possible. Immunai is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. About the role: This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills. Location: New York City (On-site role) What will you do? * Augment efforts of teams using a wide range of techniques including, but not limited to immune cell isolation and processing from human specimens, cell cultures and in vitro model systems * Domain expert with single cell genomics methods, and proven experience of innovation in this field (sample optimization, protocol development). * Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware * Maintenance of a complete, accurate, and timely electronic record of all experiments using an informatics management system. * Active participation in cross-functional team meetings and effective communication with other members of the lab, computational biology, and software team * Expected to deliver impactful presentations to other colleagues including senior leadership Requirements Required qualifications: * 4-6 years of experience in Molecular Biology or Immunology; * MS with 2-4 years relevant experience, PhD with 1+ years of post-PhD experience is preferred. * Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes. Additionally, familiarity with high-throughput, automated single cell profiling workflows is preferred. * Experience working with tissue samples, including single cell dissociation. * Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage * Familiarity with high throughput lab data management (e.g. Benchling) * Strong analytical skills, problem solving ability, and innovation aptitude required * Must be willing to discover and learn new software and technology applications quickly * Must have strong attention to detail and an ability to multitask * Ability to collaborate closely with interdisciplinary individuals from a broad range of backgrounds * Ability to work independently with minimal supervision * Ability to work successfully in a fast-paced environment * Excellent interpersonal skills and ability to effectively work as part of a team are essential * Excellent organization and time management skills Desired personal traits: * You want to make an impact on humankind * You prioritize "We" over "I" * You enjoy getting things done and striving for excellence * You collaborate effectively with people of diverse backgrounds and cultures * You have a growth mindset * You are candid, authentic, and transparent Compensation: This position offers a salary typically between $105,000 - $140,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills. * Please note that when you apply for a position at Immunai, your application will be processed via our recruitment platform SparkHire. You can read more about how we process personal data here: ***************************************
    $105k-140k yearly 42d ago
  • Machine Learning Scientist

    Jpmorgan Chase Bank, N.A 4.8company rating

    Senior principal scientist job in Jersey City, NJ

    The Applied Innovation of AI (AI2) team is an elite machine learning group strategically located within the Chief Technology Office of JP Morgan Chase. AI2 tackle business critical priorities using innovative machine learning techniques and technologies with a focus on machine learning for Software, Cybersecurity and Technology Infrastructure. The team partners closely with stakeholders in these areas to execute projects that require machine learning development to support JPMC businesses as they grow. Strategically positioned in the Chief Technology Office, our work spans across Cybersecurity, Global Technology Infrastructure and the Software Development Lifecycle (SDLC). With this unparalleled access to technology groups in the firm, the role offers a unique opportunity to explore novel and complex challenges that could profoundly transform how the bank operates. As a Machine Learning Scientist, you will apply sophisticated machine learning methods to a wide variety of complex tasks including data mining and exploratory data analysis and visualisation, text understanding and embedding, anomaly detection in time series and log data, large language models (LLMs) and generative AI for technology use-cases, reinforcement learning and recommendation systems. You must excel in working in a highly collaborative environment together with the business, technologists and control partners to deploy solutions into production. You must also have a passion for machine learning and invest independent time towards learning, researching and experimenting with new innovations in the field. You must have solid expertise in Deep Learning with hands-on implementation experience and possess strong analytical thinking, a deep desire to learn and be highly motivated. Job Responsibilities Research and explore new machine learning methods through independent study, attending industry-leading conferences and experimentation Develop state-of-the art machine learning models to solve real-world problems and apply it to complex business critical problems in Cybersecurity, Software and Technology Infrastructure Collaborate with multiple partner teams in Cybersecurity, Software and Technology Infrastructure to deploy solutions into production Drive firmwide initiatives by developing large-scale frameworks to accelerate the application of machine learning models across different areas of the business Contribute to reusable code and components that are shared internally and also externally Required qualifications, capabilities and skills PhD in a quantitative discipline (e.g. Computer Science, Electrical Engineering, Mathematics, Operations Research, Optimization, or Data Science.) with 1 year experience Or Masters with 2 years of industry or research experience in the field. Hands-on experience and solid understanding of machine learning and deep learning methods Extensive experience with machine learning and deep learning toolkits (e.g.: TensorFlow, PyTorch, NumPy, Scikit-Learn, Pandas) Extensive experience with large language models (LLMs) and accompanying tools & techniques in the LLM ecosystem (e.g. LangChain, LangGraph, Vector databases, opensource Models, RAG, Agentic Systems & Workflows, LLM fine-tuning) Scientific thinking and the ability to invent Ability to design experiments and training frameworks, and to outline and evaluate intrinsic and extrinsic metrics for model performance aligned with business goals Experience with big data and scalable model training Solid written and spoken communication to effectively communicate technical concepts and results to both technical and business audiences Curious, hardworking and detail-oriented, and motivated by complex analytical problems Ability to work both independently and in highly collaborative team environments Preferred qualifications, capabilities and skills Strong background in Mathematics and Statistics Familiarity with the financial services industries Experience with A/B experimentation and data/metric-driven product development Experience with cloud-native deployment in a large scale distributed environment Published research in areas of Machine Learning, Deep Learning or Reinforcement Learning at a major conference or journal Ability to develop and debug production-quality code Familiarity with continuous integration models and unit test development JPMorganChase, one of the oldest financial institutions, offers innovative financial solutions to millions of consumers, small businesses and many of the world's most prominent corporate, institutional and government clients under the J.P. Morgan and Chase brands. Our history spans over 200 years and today we are a leader in investment banking, consumer and small business banking, commercial banking, financial transaction processing and asset management. We offer a competitive total rewards package including base salary determined based on the role, experience, skill set and location. Those in eligible roles may receive commission-based pay and/or discretionary incentive compensation, paid in the form of cash and/or forfeitable equity, awarded in recognition of individual achievements and contributions. We also offer a range of benefits and programs to meet employee needs, based on eligibility. These benefits include comprehensive health care coverage, on-site health and wellness centers, a retirement savings plan, backup childcare, tuition reimbursement, mental health support, financial coaching and more. Additional details about total compensation and benefits will be provided during the hiring process. We recognize that our people are our strength and the diverse talents they bring to our global workforce are directly linked to our success. We are an equal opportunity employer and place a high value on diversity and inclusion at our company. We do not discriminate on the basis of any protected attribute, including race, religion, color, national origin, gender, sexual orientation, gender identity, gender expression, age, marital or veteran status, pregnancy or disability, or any other basis protected under applicable law. We also make reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as mental health or physical disability needs. Visit our FAQs for more information about requesting an accommodation. JPMorgan Chase & Co. is an Equal Opportunity Employer, including Disability/Veterans Base Pay/Salary Jersey City,NJ $128,250.00 - $195,000.00 / year
    $128.3k-195k yearly 8d ago
  • Pharmacovigilance Scientist

    Artech Information System 4.8company rating

    Senior principal scientist job in Bridgewater, NJ

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description The Pharmacovigilance Scientist (PVS) will serve as a core member of the safety team and is responsible for performing proactive pharmacovigilance activities on a product, or group of products in a therapeutic area or franchise, in partnership with the Global Safety Officer (GSO) to evaluate safety data and signals for both marketed products and products in clinical development. This includes performing signal detection and safety management committee activities, authoring safety evaluations, contributing and reviewing of aggregate safety reports, assisting with ad hoc regulatory responses, facilitating signal management process for assigned products (i.e., signal tracking, data analysis, leading review meetings, presenting, etc.) in collaboration with the GSO and Pharmacoepidemiology. Additionally, the PVS will support the GSO with other safety related activities associated with new drug applications / regulatory filings, benefit risk assessment and safety risk management and support activities related to risk minimization including dRMP/RMP and REMS. The PVS will provide coordination and oversight to outsourced activities (i.e., signal detection reports, clinical overviews). Good knowledge of pharmacovigilance practices Good knowledge of US and EU pharmacovigilance regulatory requirements Excellent written and verbal communication skills Ability to present and critically discuss safety data in both internal and external discussions Ability to evaluate, interpret and synthesize scientific data (analytical thinking) Team player with ability to function in a cross-functional environment Self-motivated, able to prioritize and plan effectively, and independently, with minimal supervision Fluent in English (verbal and written) Good moderator skills Ability to navigate in databases and pull information correctly Good organizational skills and attention to detail Education: Minimum Bachelors of Science or Health Care Professional (RN, BSN, Nurse Practitioner or Physician Assistant, RPh); or preferred advanced health care discipline degree (MDPharmD, PhD, Masters of Science, etc.) or equivalent qualification. Required Experience: Basic knowledge of common data processing software (i.e., Excel, PowerPoint, Word) and database systems Additional Information Best Regards, Anuj Mehta ************
    $85k-124k yearly est. 22h ago
  • Scientist

    Nouryon

    Senior principal scientist job in Bridgewater, NJ

    At Nouryon, our global team of Changemakers takes positive action every day, to reach higher collectively and individually. We create innovative and sustainable solutions for our customers to answer society's needs - today and in the future. As a Scientist, you will be responsible for leading research projects, developing innovative solutions, and optimizing processes within your field of expertise. You will collaborate with cross-functional teams, maintain a safe working environment, and be the lead technical contact for customers. This role offers the opportunity to work on high-impact projects, with occasional travel both domestically and internationally. In your future role as Scientist you will: Maintain and promote a safe, clean, and orderly working environment Plan, set up, and execute experiments; analyze and interpret results Identify new product and process optimization opportunities Keep up-to-date with the latest research methods and ensure knowledge retention within the team Act as a lead technical contact in customer meetings and present technical information Collaborate with Intellectual Property (IP) teams to manage and file IP applications Participate in projects, ensuring timely and high-quality execution using your expertise We believe you bring: Education: PhD in Chemistry/Polymers/Material Science/Chemical Technology + 3 years of experience, OR Master's Degree + 5 years of experience, OR Bachelor's Degree + 10 years of experience in relevant fields Preferred: PhD with 5+ years of experience Experience: Required: Laboratory experience in chemistry, polymers, or material science Strongly Preferred: Experience with surfactants and/or polymer formulation technology in Agro applications Skills and Competencies: Strong communication and presentation skills Expertise in designing, executing, and analyzing experiments Knowledge of experimental design and data interpretation Ability to deliver results on large projects, meeting business needs on time. Good to know: This is a permanent on-site position on a full-time basis, reporting to the Section Manager in Bridgewater, NJ. Please apply via our online recruitment system. We will not accept applications via e-mail. Once it's with us we will review to see if we have a match between your skills and the role! For more information about our hiring process, visit: nouryon.com/careers/how-we-hire/ We look forward to receiving your application! We kindly ask our internal candidates to apply with your Nouryon email via Success Factors. About Nouryon: We're looking for tomorrow's Changemakers, today. If you're looking for your next career move, apply today and join Nouryon's worldwide team of Changemakers in providing essential solutions that our customers use to manufacture everyday products such as personal care, cleaning, paints and coatings, agriculture and food, pharmaceuticals, and building products. Our employees are driven by the desire to make an impact and actively drive positive change. If that describes you, we will gladly make way for your ambitions. From day one, we support you with your personal growth, through challenging positions and comprehensive learning and development opportunities, in a dynamic, international, diverse, and proactive working environment. Visit our website and follow us on LinkedIn. #WeAreNouryon #Changemakers We have already chosen our sourcing channels for this recruitment and kindly ask not to be contacted by any advertisement agents, recruitment agencies or staffing companies. " What can Nouryon offer you? If you share our values and ambitions, we offer a fascinating international environment that rewards your skills and enthusiasm. Our employment package comprises a competitive salary and an attractive bonus scheme. Training opportunities and internal networks enable valuable personal and professional development. And through challenging projects you will help us become first choice for our customers, shareholders and employees, all over the world. Nouryon is an Equal Opportunity Employer - Minorities / Females / Disabled / Veterans (M/F/D/V) Application details If you have questions on the role, please contact [[Hiring Manager]]. For further information on the recruitment process, please contact [[Recruiter Name]], Recruiter. We welcome your online application via our website. Please use the apply button on this page. A pre-employment screening may form part of the selection process. We have already chosen our sourcing channels for this recruitment and kindly ask not to be contacted by any advertisement agents, recruitment agencies or manning companies. About Nouryon: We are a global specialty chemicals leader. Industries worldwide rely on our essential chemistry in the manufacture of everyday products such as paper, plastics, building materials, food, pharmaceuticals, and personal care items. Building on our nearly 400-year history, the dedication of our 10,000 employees, and our shared commitment to business growth, strong financial performance, safety, sustainability, and innovation, we have established a world-class business and built strong partnerships with our customers. We operate in over 80 countries around the world and our portfolio of industry-leading brands includes Eka, Dissolvine, Trigonox, and Berol. "
    $77k-113k yearly est. 60d+ ago
  • Machine Learning Scientist

    JPMC

    Senior principal scientist job in Jersey City, NJ

    The Applied Innovation of AI (AI2) team is an elite machine learning group strategically located within the Chief Technology Office of JP Morgan Chase. AI2 tackle business critical priorities using innovative machine learning techniques and technologies with a focus on machine learning for Software, Cybersecurity and Technology Infrastructure. The team partners closely with stakeholders in these areas to execute projects that require machine learning development to support JPMC businesses as they grow. Strategically positioned in the Chief Technology Office, our work spans across Cybersecurity, Global Technology Infrastructure and the Software Development Lifecycle (SDLC). With this unparalleled access to technology groups in the firm, the role offers a unique opportunity to explore novel and complex challenges that could profoundly transform how the bank operates. As a Machine Learning Scientist, you will apply sophisticated machine learning methods to a wide variety of complex tasks including data mining and exploratory data analysis and visualisation, text understanding and embedding, anomaly detection in time series and log data, large language models (LLMs) and generative AI for technology use-cases, reinforcement learning and recommendation systems. You must excel in working in a highly collaborative environment together with the business, technologists and control partners to deploy solutions into production. You must also have a passion for machine learning and invest independent time towards learning, researching and experimenting with new innovations in the field. You must have solid expertise in Deep Learning with hands-on implementation experience and possess strong analytical thinking, a deep desire to learn and be highly motivated. Job Responsibilities Research and explore new machine learning methods through independent study, attending industry-leading conferences and experimentation Develop state-of-the art machine learning models to solve real-world problems and apply it to complex business critical problems in Cybersecurity, Software and Technology Infrastructure Collaborate with multiple partner teams in Cybersecurity, Software and Technology Infrastructure to deploy solutions into production Drive firmwide initiatives by developing large-scale frameworks to accelerate the application of machine learning models across different areas of the business Contribute to reusable code and components that are shared internally and also externally Required qualifications, capabilities and skills PhD in a quantitative discipline (e.g. Computer Science, Electrical Engineering, Mathematics, Operations Research, Optimization, or Data Science.) with 1 year experience Or Masters with 2 years of industry or research experience in the field. Hands-on experience and solid understanding of machine learning and deep learning methods Extensive experience with machine learning and deep learning toolkits (e.g.: TensorFlow, PyTorch, NumPy, Scikit-Learn, Pandas) Extensive experience with large language models (LLMs) and accompanying tools & techniques in the LLM ecosystem (e.g. LangChain, LangGraph, Vector databases, opensource Models, RAG, Agentic Systems & Workflows, LLM fine-tuning) Scientific thinking and the ability to invent Ability to design experiments and training frameworks, and to outline and evaluate intrinsic and extrinsic metrics for model performance aligned with business goals Experience with big data and scalable model training Solid written and spoken communication to effectively communicate technical concepts and results to both technical and business audiences Curious, hardworking and detail-oriented, and motivated by complex analytical problems Ability to work both independently and in highly collaborative team environments Preferred qualifications, capabilities and skills Strong background in Mathematics and Statistics Familiarity with the financial services industries Experience with A/B experimentation and data/metric-driven product development Experience with cloud-native deployment in a large scale distributed environment Published research in areas of Machine Learning, Deep Learning or Reinforcement Learning at a major conference or journal Ability to develop and debug production-quality code Familiarity with continuous integration models and unit test development
    $78k-113k yearly est. Auto-Apply 8d ago
  • Scientist II, Immunology

    Deerfield Management Companies 4.4company rating

    Senior principal scientist job in New York, NY

    Job Title: Scientist II- Immunology Anvia Therapeutics is a dynamic and innovative biotech company dedicated to developing small molecule inhibitors targeted at treating inflammatory and autoimmune diseases. We foster a collaborative environment where scientific excellence and creativity drive our mission to develop impactful medicines. Job Summary We are seeking a highly motivated immunology Scientist to drive hypothesis-driven in vitro immunology research in a fast-paced and innovative drug discovery environment. The successful candidate will design, develop, and execute complex cellular assay systems, including primary human immune cells, patient-derived samples, and disease-relevant cell lines to support immune pharmacology and mechanism-of-action (MoA) studies across inflammatory disease programs such as IBD, rheumatoid arthritis, and dermal inflammation. Responsibilities Key Responsibilities Design and execute hypothesis-driven cellular assays to support immune pharmacology, target validation, and MoA studies. Develop, optimize, and validate complex in vitro assay systems using primary immune cells, patient-derived samples, and disease-relevant or engineered cell lines. Perform functional immune assays including cell activation, proliferation, cytokine production, signaling, and cytotoxicity, using both primary and cell-line-based systems. Contribute to immune pharmacology assessments, including compound potency, pathway modulation, selectivity, and translational relevance. Apply a strong mechanistic understanding of immune and inflammatory signaling pathways to guide assay design and data interpretation. Utilize flow cytometry, ELISA/MSD/other cytokine/chemokine profiling techniques, protein- and signaling-based assays, and related techniques to generate high-quality, reproducible data. Analyze, interpret, and clearly communicate experimental results to project and leadership teams. Troubleshoot and refine experimental systems to improve robustness, scalability, and biological relevance. Maintain accurate experimental records using electronic laboratory notebooks. Collaborate closely with lead discovery, chemistry, translational, and external partners to advance program milestones. Stay current with emerging immunology technologies and incorporate innovative methodologies where appropriate. Qualifications Required Qualifications PhD in Immunology, Biology, Biotechnology, Molecular Biology, or a related field with 2+ years of relevant experience. Hands-on experience developing and executing complex cellular assays using primary immune cells, patient-derived samples, and cell line-based systems. Experience working with functional immune readouts, including flow cytometry-based phenotyping and signaling assays, and cytokine measurement (ELISA/MSD/other). Demonstrated expertise in protein-level analysis of signaling pathways, including Western blotting and related biochemical techniques used to assess pathway activation, inhibition, and mechanism of action. Strong understanding of cell signaling pathways relevant to immune and inflammatory biology. Proven ability to independently design experiments, troubleshoot assays, and manage multiple priorities. Proficiency with data analysis and visualization tools (e.g., GraphPad Prism, FlowJo, Excel). Excellent written and verbal communication skills. Preferred Qualifications Experience supporting immune pharmacology and MoA characterization in early drug discovery. Background in inflammatory or autoimmune disease biology (IBD, RA, dermatology preferred). Familiarity with assay validation, quantitative potency assessment and translational biomarker analysis/ identification. Experience working in a fast-paced, innovative biotech environment. Why Join Us? Be part of a passionate team making a difference in biotech innovation. Collaborative and dynamic work environment. Hands-on experience with state-of-the-art technologies. Opportunities for professional development and advancement. Competitive compensation and benefits. The salary range for this position is $115,000-$150,000 per year. The actual compensation offered will be based on factors such as relevant experience, education, and skills. In addition to base salary, we offer a comprehensive benefits package, including health insurance, paid time off, and retirement plan options. Anvia Therapeutics is an equal opportunity employer. We do not discriminate against any employee or applicant for employment because of race, creed (religion), color, national origin, sex (including gender identity and sexual orientation), age, disability, marital status, citizenship status, military status, genetic information, or any other characteristic protected by federal, state, or local law. Our employment decisions are based on merit, qualifications, and business needs. We are committed to providing a work environment free from discrimination, harassment, and retaliation, and we undertake affirmative action efforts to promote equal opportunity for all employees and applicants. #LI-DNI
    $115k-150k yearly Auto-Apply 31d ago
  • Scientist Ops- 1st Shift

    Compass Consulting

    Senior principal scientist job in Branchburg, NJ

    Our client develops, manufactures and supplies a wide array of innovative medical diagnostic products, services, tests, platforms and technologies. Scientist is needed for the support of overall Technical Support objectives. The successful candidate will conduct non-routine laboratory experiments designed to implement new technologies or investigate basic scientific questions relevant to customer complaints/technical issues with Polymerase Chain Reaction (PCR) assays and reagents and project responsibilities. Designs, plans and executes assigned investigation/trouble shooting activities, research/development related experiments/projects and applying scientific knowledge and accumulated experience to complete projects. Need to accurately record information and make sound scientific interpretation of experimental results, which are to be communicated to non-scientific audience through investigational reports and verbal presentations. The successful candidate should have deductive reasoning and critical thinking in their tasks as they attempt to enact change to processes and reinforce new methodology in solving problems. Establish priorities, create and maintain time frames, and report status of project's progress toward established project goals and deadlines. Prepare regular, internal project update reports and comprehensive project status reviews as required. Keeps supervisor informed of status of all projects, particularly of significant findings and results in critical problem areas. Ensures that technical activities under delegated supervision are conducted with the framework of both internal (e.g., Safety Regulations) and external (e.g., OSHA) guidelines and regulation.
    $77k-112k yearly est. 60d+ ago
  • MSAT Scientist Mass Spectrometry - Life Sciences - M/F/X

    Akkodis

    Senior principal scientist job in Succasunna, NJ

    About the role The position involves working within the Recombinant Mammalian Drug Substance function, which is part of the global Manufacturing Science, Analytics, and Technology organization. The role includes tech transfer activities of mass spectrometry-based methods, method execution, optimization, and report writing to support product launches and life cycle management About you * Develop, optimize, and execute liquid-chromatography coupled to mass spectrometry methods * Serve as an expert in analytical HPLC and mass spectrometry techniques * Integrate LC-MS data with process and product knowledge for comprehensive analysis * Manage end-to-end method responsibility from development to execution and documentation * Identify improvements for existing methods to enhance robustness and reduce cycle time About you * PhD or Master in Life Sciences with mandatory mass spectrometry experience * Prior hands-on experience with LC-MS is essential for this role * Experience interpreting large molecule LC-MS data at intact or peptide levels is advantageous * Strong understanding of chromatography methods and mass spectrometry for project acceleration * At least 3 years of experience in method development, validation, and investigation testing/support
    $77k-113k yearly est. 51d ago
  • Scientist II, Immuno-Oncology

    Cellectis

    Senior principal scientist job in New York, NY

    Scientist II, Immuno-Oncology FUNCTIONAL AREA: REPORTS TO: Team Leader EXEMPT/NON-EXEMPT In the Immuno-Oncology team, we are looking for an enthusiastic, inventive and team-oriented scientist to join us in the creation cutting-edge cellular treatments for cancer and other serious diseases. We are looking for colleagues with a strong background in one or multiple areas including: Immuno-Oncology, Oncology or Immunology, and who possess strong expertise in T-cell biology, intricate multicolor flow cytometry, and in vivo mouse models. The ideal candidate would have a remarkable scientific record, excellent communication and interpersonal abilities, be passionate about scientific research, and excel at pushing boundaries for innovation. We value candidates who are adept at problem-solving and approach difficulties with optimism. The chosen individual will join a dynamic, creative and goal-oriented atmosphere dedicated to making impactful advances in the way we treat disease. Responsibilities Responsibilities include, but are not limited to: Develop innovative adoptive cell therapies to treat cancer or other serious diseases. Design, execute, and analyze in vitro experiments (some examples include engineering of CAR T-cells, cytotox, ELISA, proliferation assays, flow cytometry analysis, cell culture). Design, execute and analyze in vivo preclinical studies (some examples of procedures include tumor implantation, adoptive cell therapy administration, mice dosing through different administration routes, tumor monitoring, blood collection and multiple tissue analysis). Efficiently and clearly present and communicate scientific data to the team, cross-functionally and at external meetings. Pro-actively suggest and evaluate innovative cell engineering solutions and develop new assays to enhance the company's intellectual portfolio and contribute to peer-reviewed publications. Stay up to date with external scientific research from academic and industry institutions. Keep timely detailed documentation of experiments. Effectively plan and manage projects and deliverables to meet deadlines. Foster cross-functional collaborations and train other colleagues. Prioritize company objectives and work towards shared success. Other duties as necessary to ensure the daily operations of the lab and support the team. Core Competencies Keen eye for detail, exceptional problem-solving abilities, and a commitment to producing robust and high-quality scientific data for internal/external reports, publications and IND-enabling studies Strong scientific creativity and analytical thinking skills. Curiosity and drive to initiate and advance programs to treat diverse important diseases. Excellent written, oral and interpersonal communication skills. Capable of adhering to SOP and develop new protocols. Works well autonomously and collaboratively with other team members and cross-functionally. Flexibility and ability to adapt positively to a dynamic environment with changing priorities. Pro-active, transparent and adaptable team-player with a professional demeanor who works well under pressure. Comfortable operating in a fast-paced, small-midsized company environment. Requirements PhD in oncology, immunology, or equivalent (minimum of 3 years of experience after PhD in related role). Experience in human T-cell biology, immuno-oncology and knowledge in cell engineering technologies. Hands on experience and troubleshooting proficiency in immunology assays including immune cell isolation, multicolor flow cytometry, immune cell and cytokine profiling assays using conventional and next-generation analytical methods. Demonstrated experience designing and executing mouse tumor model experiments including mouse handling (injections- IV, SC, IP- and organ dissection). Excellent abilities to analyze and synthesize data for different audiences and report types while supporting decision-making processes. Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired. Basic knowledge of gene editing and next-generation sequencing technologies is a plus. Experience in working in matrixed environments and in project management is desired. Strong record of scientific publications and demonstrated scientific curiosity. Willingness to quickly adapt, innovate, discover new approaches, collaborate and support the team towards shared company goals. Candidates should be authorized to work in the U.S., preferably without the need for current, or future, sponsorship. Role is onsite and based in New York, NY Physical Requirements Sedentary - primarily involves sitting and/or standing. Laboratory work performed within a BSL1 and BSL2 environments. Communicates with others daily to exchange information. Salary Range (105,000 to 115,000 USD), dependent on skills and experience
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • ML Scientist

    Layer Health

    Senior principal scientist job in New York, NY

    Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the mission to reduce friction everywhere in healthcare. Our LLM-powered platform is solving chart review once and for all, across use cases. For health systems, our first product dramatically accelerates clinical registry abstraction in areas ranging from surgery and cardiology, to oncology. Our long term vision is for our AI layer to safely transform patient care and minimize unnecessary heartbreak. Layer Health's diverse founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We're seeking outstanding hires to join our team as early members. This is an opportunity to contribute to a high-impact, collaborative, mission-driven team, and help define the next stage of growth for Layer Health. Together, we will create the AI layer that will redefine healthcare for the better. Here's a collection of articles about our product, mission, recent funding round, etc. Job Description We're hiring an exceptional ML scientist. In this role, you will be responsible for pioneering innovative machine learning techniques to advance our fundamental clinical machine learning and large language model efforts. You can expect to: Design and implement state-of-the-art machine learning techniques to advance Layer Health's research agenda (in areas such as information extraction, multimodal reasoning, and summarization). Propose new agentic methods that tackle fundamental NLP and ML challenges such as modeling over multiple documents, long contexts, multiple modalities, and with limited or noisy labels Build foundation models to power the future of clinical information extraction & synthesis, from training through inference. Stay up-to-date and actively engage with cutting-edge research in NLP, generative AI, and clinical machine learning. Collaborate with the broader engineering team to ship performant products that meet user needs. Cultivate and foster a robust and thoughtful R&D culture that drives the company forward. We look for: Exceptional methodological research background and experience, including but not limited to: A PhD in computer science/applied mathematics or equivalent research experience, specializing in natural language processing and machine learning. High-impact, early-author publications at top peer-reviewed ML journals/conferences. Demonstrated record of delivering real-world impact from start to finish- with the ability to design, develop, and ship innovations. Strong programming skills and fluency with modern machine learning/LLM stacks (deep learning libraries e.g. PyTorch, Jax). Past experience in training/inference of foundation models (billions of parameters, distributed training, familiarity with state-of-the-art techniques). A strong communicator who thrives in a customer-focused, fast-paced environment. An excited and adaptable team player who wants to disrupt the healthcare industry with AI/ML, alongside an awesome team. Past experience in healthcare of life sciences is a plus, but not required. We are a Boston-based company, and expect employees to meet regularly in-person in Boston (employees from Boston, NYC, or east coast are welcome). Expected compensation range for this role is $200,000-250,000, in addition to stock options. Compensation is dependent on experience, overall fit to our role, and candidate location. Expected compensation ranges for this role may change over time. If your compensation requirement is greater than our posted salary ranges, please still consider applying to our role. We will make a determination as to whether an exception can be made. If you are excited about this role, we encourage you to apply even if you don't feel that you meet every single requirement. We're eager to meet people that believe in our mission and can contribute to our team in a variety of ways. We welcome diverse perspectives, rigorous thinking, and fearlessness in challenging the status quo. Layer Health is committed to fostering an environment of inclusion that is free from discrimination. We are an Equal Opportunity Employer where employment is decided on the basis of qualifications, merit, and business need. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected Veteran status, or any other characteristic protected by law. Join us and help us transform healthcare with AI.
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • Machine Learning Scientist

    Inductive Bio

    Senior principal scientist job in New York, NY

    Drug discovery is a prediction problem. Scientists design molecules that they predict will be potent, safe, and readily absorbed into the body, but ultimately lab experiments must be run to know whether these predictions are accurate. Each one of these experiments can take weeks or months to run, and as a result it costs millions of dollars and takes years to design a molecule that is ready for testing in humans. At Inductive Bio, we're using AI to build in silico models that can more accurately predict how molecules will behave in experiments. By predicting complex molecular properties directly from the molecular structure, our platform helps scientists make better decisions faster-ultimately bringing safer, higher-quality medicines to patients more quickly. We are enabled by a unique and growing proprietary data set, and we are already applying our methods to dozens of active drug discovery programs. Backed by leading investors at the intersection of biotechnology and technology and advised by renowned experts in drug discovery, we are growing rapidly and poised to make a major impact in drug discovery. We are seeking Machine Learning Scientists to join our talented, ambitious, and kind team. You'll have the opportunity to innovate on methods, work with leading drug discovery scientists, and apply your work immediately to drug programs at some of the most innovative biotechs in the world. As an early machine learning scientist at a rapidly-growing startup, you'll have the opportunity for high impact while learning and growing with the company. What you'll do: Develop machine learning models to predict molecular properties from chemical structures Develop novel algorithms for generating ideas for new molecules Build agents that can synthesize complex information from drug programs and apply that information strategically toward molecular optimization Get your hands dirty by diving deep into our unique, proprietary dataset to iterate on modeling ideas and improve model performance Collaborate closely with chemists and software engineers to integrate models into our software platform, which is used by drug discovery scientists across the industry Build and optimize scalable infrastructure for model training, deployment, and monitoring Engage directly with our scientific users, incorporating their feedback into the product Contribute meaningfully to product strategy and company direction Who you are: You have 4+ years of experience as a Machine Learning Scientist, Machine Learning Engineer, Data Scientist, or similar role You have expertise in machine learning fundamentals, deep learning architectures, and evaluation approaches You are proficient in standard Python-based ML frameworks (e.g. PyTorch, TensorFlow, scikit-learn) You are comfortable writing high-quality, reusable code and productionizing models for serving in the cloud You are excited to dive deep into the science and practice of drug discovery You have exceptional written and oral communication skills Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • Job Opportunities Senior Toxicologist (DART)

    Givaudan 4.9company rating

    Senior principal scientist job in East Hanover, NJ

    Join us and celebrate the beauty of human experience. Create for happier, healthier lives, with love for nature. Together, with passion and creativity, we deliver food innovations, craft inspired fragrances and develop beauty and wellbeing solutions. There's much to learn and many to learn from, with more than 16,000 employees around the world to explore ideas and ambitions with. Every day, your talent, your innovative spirit, and your determination will shape our future, making a positive difference on billions of people. Every essence of you enriches our world. We are Givaudan. Human by nature. Senior Toxicologist - Specialist in Developmental and Reproductive Toxicology (DART) You will play an important role as our in-house expert on Developmental and Reproductive Toxicology (DART), strengthening our safety science capabilities, ensuring compliance with global regulatory standards, and contributing to innovative approaches for reproductive and developmental safety assessment under a regulatory landscape that is quickly evolving. You will help create product safety documentation for registration with relevant authorities and provide scientific guidance to all partners. Reporting to the Head of Fragrance Human Safety Sciences, you will be based close to one of our Regulatory Fragrance Offices (Paris, Ashford, or Ridgedale (NJ, USA)), working four days onsite and one from home each week. Main Responsibilities Product Safety & Scientific Leadership Be Givaudan's internal expert for Developmental and Reproductive Toxicology (DART). Provide excellence in human health safety to demonstrate the safe use of our ingredients and products to customers and regulators. Plan, coordinate, and oversee pre-clinical DART studies following OECD, ICH, and other regulatory guidelines. Define and monitor safety testing strategies in compliance with REACH, TSCA, and other global regulations. Work with CROs on study monitoring, reporting, and strategic planning; past study director experience in reputed toxicology CROs is a strong asset. Contribute to the development and application of New Approach Methodologies (NAMs) for reproductive and developmental toxicity testing (in vitro, in silico, and alternative models). Regulatory Policy & Advocacy Provide Givaudan management with expert guidance on complex regulatory and safety issues. Interpret scientific and technical data affecting Givaudan's global regulatory toxicology activities. Represent Givaudan on industry safety committees and contribute to trade association initiatives. Product Documentation & Registration Lead efforts to obtain relevant toxicology or regulatory data needed to support product registrations. Act as the liaison between R&D project teams and product safety functions. You - Your Profile Includes PhD required in toxicology, biochemistry, chemistry, or related scientific discipline. 10-15 years of expertise in pre-clinical studies within the field of Developmental and Reproductive Toxicology/Biology. Demonstrated track record in planning, coordinating, and accomplishing DART studies following OECD, ICH, and other regulatory guidelines. Past experience as a DART-specialized study director in a reputed toxicology testing CRO Familiarity with digital fundamentals (AI, machine learning for advanced data analysis). Familiarity with global regulatory frameworks relevant to reproductive and developmental toxicity. Fluent in English (spoken and written). For US: Salary expectation based on technical experience: 120,000 - 160,000 usd Location: The position will be based on the candidate's current location (UK, France, or US) Our Benefits: Annual bonus. Medical insurance coverage. Career Development Opportunities with access to many virtual learning sessions International working environment #LI-Onsite #ZR At Givaudan, you contribute to delightful taste and scent experiences that touch people's lives. You work within an inspiring teamwork culture - where you can thrive, collaborate and learn from other talented and passionate people across disciplines, regions and divisions. Every essence of you enriches our world. Diversity drives innovation and creates closer connections with our employees, customers and partners. Givaudan embraces diversity and is committed to building an inclusive environment where everyone impacts our world.
    $85k-132k yearly est. 60d+ ago

Learn more about senior principal scientist jobs

How much does a senior principal scientist earn in Irvington, NJ?

The average senior principal scientist in Irvington, NJ earns between $91,000 and $178,000 annually. This compares to the national average senior principal scientist range of $83,000 to $169,000.

Average senior principal scientist salary in Irvington, NJ

$127,000

What are the biggest employers of Senior Principal Scientists in Irvington, NJ?

The biggest employers of Senior Principal Scientists in Irvington, NJ are:
  1. Msd International Gmbh
  2. Merck
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