Senior Principal Scientist Jobs in Lower Makefield, PA
- 588 Jobs
Principal Scientist, Discovery & Preclinical Pharmacology
The Principal Scientist shall be responsible for independently developing, maintaining and conveying key technical knowledge to move candidates through lead selection and IND. The Principal Scientist will lead basic research on rare disease biological mechanisms and optimize the pharmacological activity of drug candidates that intervene with the disease. Larimar Therapeutics Inc (Bala Cynwyd, PA) is a clinical-stage biotechnology company focused on developing treatments for complex rare diseases.$80k-114k yearly est.2d ago
This Postdoctoral Researcher position is fully funded for three years and renewable after three years, and salary will be commensurate with NIH guidelines based on Postdoc years of experience. Discover why Cooper University Health Care is the employer of choice in South Jersey. At Cooper University Health Care, our commitment to providing extraordinary health care begins with our team. The Postdoctoral Researcher will study esophageal cancer and potentially lung cancer under the direction of Dr. Luke Chen, using cancer cells, mouse models and human tisues. The Surgical Research Laboratory, Department of Surgery, Cooper University Hospital and Cooper Medical School of Rowan University (CMSRU) is seeking to fill a Postdoctoral Researcher position to study targeted therapy of upper aerodigestive tract cancer.$53k-68k yearly est.15d ago
Scientist/Senior/Principal Scientist, Proteomics
We are seeking a highly motivated and experienced Senior Scientist with expertise in chemoproteomics/proteomics, mass spectrometry, and liquid chromatography.
Develop and optimize proteomic and chemoproteomic workflows, including sample preparation, LC-MS/MS analysis, data processing, and bioinformatics analysis.
Design and execute experiments to investigate protein-protein interactions, post-translational modifications, and protein dynamics in a variety of biological contexts.
Analyze and interpret complex data sets, generate hypotheses, and provide insights to guide research projects.
Collaborate with interdisciplinary teams to integrate proteomics data with other omics data and functional assays to generate a comprehensive understanding of biological systems.
Supervise and mentor junior scientists, provide technical guidance and leadership, and participate in the development of research strategies and grant proposals.
Stay current with the latest scientific literature, technologies, and methodologies in proteomics and chemoproteomics.
Ph.D. in Chemistry, Biochemistry, or a related field with a focus on proteomics or chemoproteomics.
At least 5 years of hands-on experience in developing and applying proteomic/chemoproteomic techniques, including sample preparation, LC-MS/MS analysis, and data analysis.
Strong expertise in mass spectrometry instrumentation, including Orbitrap, Q-TOF, and triple quadrupole platforms, and software packages for data analysis such as MaxQuant, Proteome Discoverer, and Skyline.
Experience in liquid chromatography techniques, including nano-LC and HPLC.
Strong track record of scientific publications and presentations.
Excellent problem-solving skills, attention to detail, and ability to work independently and collaboratively in a team environment.
Strong leadership skills, including the ability to supervise and mentor junior scientists.
Excellent communication skills, including the ability to present complex data and concepts in a clear and concise manner.
If you have a passion for innovation, a track record of scientific excellence, and a desire to work in a dynamic, collaborative environment, we encourage you to apply for this exciting opportunity as a Senior Scientist in chemoproteomics/proteomics.
Please note that this position is an on-site role.
If you are interested in this position, then please share your resume for immediate consideration!$95k-153k yearly est.21d ago
Y - Bioinformatics Scientist in Lawrenceville, NJ, US
Summary: We are seeking a passionate scientist to join our Disease Strategy and Late Stage Hematology team in the Translational Bioinformatics group. 50%Onsite Senior Research Scientist, Disease Strategy and Late Stage Hematology, Translational Bioinformatics$78k-112k yearly est.6d ago
Title: Scientist - I (Assistant) Responsibilities: Bioanalytical Scientist responsibilities include, but are not limited to, the following:$53k-78k yearly est.8d ago
Senior Clinical Scientist
You can find out more about Kaitlyn & Meet at www.peoplewithchemsitry.com Meet is currently working with a start-up biotech company who are searching for a Sr. Clinical Scientist or AD. This position is being dealt with by Kaitlyn Sumner at Meet. The Senior Clinical Scientist will be responsible for designing and delivering clinical studies/programs through the pipeline.$110k-136k yearly est.2d ago
Scientist to join the team.$81k-123k yearly est.15d ago
Location: Spring House, PA The Biologics Discovery department at Spring House is committed to discovering first-in-class biotherapeutics for some of the world's most challenging diseases.$65k-91k yearly est.2d ago
Synbio Technologies is looking for an Associate Scientist to join the production team, which focuses on developing and commercializing gene synthesis and sequencing platforms. This Associate Scientist will collaborate with the Business Development, Project Management, and Marketing team to deliver research projects and launch new products. Synbio Technologies is committed to discovering and developing cutting-edge DNA technologies for the advancement of life science, synthetic biology, drug discovery and development, diagnostics and precision medicine and digital information DNA storages, etc. Synbio Technologies has built a comprehensive DNA reading (sequencing), DNA writing and DNA editing platforms enabling us to aid customers in one-stop DNA solutions.$67k-98k yearly est.19d ago
Scientist 2 - Research and Development (contract)
Location: Raritan, NJ$79k-109k yearly est.5d ago
Associate Scientist, In Vivo
This is a great opportunity for an In Vivo Associate Scientist to join and grow with an expanding Biotech company.$55k-81k yearly est.15d ago
About Ascendia Pharmaceuticals:
Ascendia is a specialty pharmaceutical Research and Development CDMO company dedicated to developing enhanced formulations of existing drug products, and enabling formulations for pre-clinical and clinical stage drug candidates. Ascendia specializes in creating formulations for poorly-water soluble molecules using nano-particle technologies. Ascendia assesses the feasibility of a broad array of formulation options in order to improve a drug's bioavailability and solubility. Ascendia's technologies include nano-emulsions, amorphous solid dispersions, nano-particles, injectable, and oral controlled release. Ascendia provides development and testing services - from discovery-stage molecules to life-cycle-management projects - creating formulation solutions with enhanced biopharmaceutical properties suitable for clinical scale-up.
The mission of our company is to provide customized formulation solutions to “salvage” difficult compounds and to create advanced medicines to help patients “prevail” over their disease and enhance quality of life.
About the Position:
The qualified candidate will take an active role in supporting drug development by applying a variety of analytical methodologies to support physical and chemical characterization of drug substances (including raw materials and intermediates), biologics, and drug products. Working knowledge of analytical (e.g., HPLC-UV, HPLC-MS, GC-MS, spectroscopy) and physical chemical techniques (e.g., particle size, dissolution) used for the characterization of pharmaceutical substances and products is desired. Hand-on experience in HPLC method development and biological characterization is highly desired. Position level varies from bench chemist to principle scientist, depending on experience.
The individual will be responsible for performing laboratory work in support of analytical testing of pharmaceutical projects, and relevant experience with the following analytical methodologies: chromatography, dissolution, KF, particle size will be desirable. Job responsibilities may include analytical method development and validation; stability and release testing; testing to support pharmaceutical development efforts; direct interaction with project team members, including presentation of data; critical review of data; preparation of technical reports; and evaluation of new instrumentation or analytical techniques. The candidate must be able to interact effectively with peers and leaders as part of a multi-disciplinary team and work in a fast-paced environment. Attention to detail, strong organizational skills, the ability to multitask, and effective interpersonal and communication skills are required.
The position requires a B.S, M.S. or Ph.D. in Pharmaceutical Chemistry, Analytical Chemistry, Biology, Bioengineering, Chemistry, or Pharmaceutical Sciences with relevant working experience in pharmaceutical industry.
Working knowledge in analytical method development and validation under cGMP environment, esp biological characterization is highly desired.
Experience with a wide-variety of software and information systems (e.g. Empower, ChemStation, or LIMS).
Experience in problem-solving skills and instrument trouble-shooting.
Good oral and written communication skills and the ability to write and review technical reports and scientific papers are desired.
Working knowledge of pharmaceutical product development, CMC regulatory requirements, project management; and capability to collaborate with colleagues.
$79k-113k yearly est.16d ago
Sr. Research Associate/Associate Scientist, Cell Engineering
Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Role: The Sr. Research Associate/Associate Scientist will utilize their experience and knowledge to design and execute research and development activities focused on engineered cell therapy technologies, with a focus on engineered immune cells. Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells. Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity.$56k-85k yearly est.9d ago
Scientist/Sr. Scientist - Chemoproteomics
They are currently seeking a motivated and experienced Scientist/Senior Scientist to join their dynamic team of scientists.$78k-111k yearly est.23d ago
Senior Food Scientist (Hybrid)
The Senior Food Scientist, Cookies & Crackers Senior Food Scientist, Cookies & Crackers$85.9k-158.9k yearly4d ago
Translational Bioinformatics Research Scientist
Project Description: Our client is seeking a passionate scientist to join their Disease Strategy and Late-Stage Hematology team in the Translational Bioinformatics group.$89k-130k yearly est.6d ago
Sr. Research Scientist, Translational Bioinformatics
Hays is committed to building a thriv A Pharmaceutical Company is seeking a Sr. Research Scientist, Translational Bioinformatics in Lawrenceville, NJ. Visit the Hays Career Advice section to learn top tips to help you stand out from the crowd when job hunting. Your Hays recruiter will lead you through a thorough screening process in order to understand your skills, experience, needs, and drivers. Sr. Research Scientist, Translational Bioinformatics - Contract -Lawrenceville, NJ - $48.00-$58.00/hr. This position is a contract/temporary role where Hays offers you the opportunity to enroll in full medical benefits, dental benefits, vision benefits, 401K and Life Insurance ($20,000 benefit).$48-58 hourly2d ago
Clinical Project Scientist
The Clinical Project Scientist is responsible for the design, planning, implementation, monitoring, and reporting of clinical research trials.$54k-74k yearly est.2d ago
Senior Food Scientist, Innovation (Hybrid)
This position will be located in Camden, New Jersey.$85.9k-158.9k yearly3d ago
Associate Scientist, iPSC Biology
Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Role: The Associate Scientist will utilize their experience and knowledge to design, execute research and development activities focused on engineered cell therapy technologies, with a focus on engineered immune cells. Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells. Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity.$55k-81k yearly est.11d ago
How much does a Senior Principal Scientist earn in Lower Makefield, PA?
The average senior principal scientist in Lower Makefield, PA earns between $74,000 and $146,000 annually. This compares to the national average senior principal scientist range of $83,000 to $169,000.
What is the job market like for senior principal scientists in Lower Makefield, PA?
You can compare the number of available jobs in Lower Makefield to the number of senior principal scientist jobs in surrounding cities.
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