Senior principal scientist jobs in New York, NY

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team This position does not require you to be medical qualified. Demonstrates diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical

PRIMARY FUNCTION Director/Senior Director plays a key role as clinical technical lead on global Phase I-III and other clinical pharmacology centric projects Serves as a team member supporting multiple facets of Clinical Pharmacology, including study design, PK and PK/PD analyses, and overall drug development support. This position is also the scientific and medical/clinical liaison between internal teams and external groups such as clinical operations, vendors (CROs, central laboratories, etc.), investigators, medical monitors, regulatory authorities, medical affairs, commercial, Key Opinion Leaders, Advisory Boards The candidate will have an excellent knowledge of Clinical Pharmacology principles, such as PK, PK/PD, drug metabolism, drug-drug interactions, PBPK, PopPK modeling and E-R analysis. Provides peer-reviewed interpretation of clinical pharmacology data and incorporates appropriate analyses into reports required for regulatory submissions MAJOR RESPONSIBILITIES AND DUTIES Accountable and responsible for the Clinical Pharmacology support for the HUTCHMED global portfolio Provide scientific insights that drive global clinical development decisions and support global regulatory submissions Responsible for ensuring appropriate Clinical Pharmacology representation on drug/ dosage form development and clinical teams and provision of PK/PD expertise and leadership to a project The incumbent will complete assigned work in a resourceful, self-sufficient manner and will be able to create alternative approaches to achieve desired results if needed Responsible for ensuring planning and direction of Clinical Pharmacology components of clinical programs (including clinical development plan/life cycle plan) and studies (including synopsis and protocol preparation; clinical phase oversight, reporting) Responsible for ensuring leadership of multifunctional study team to design, deliver and report the assigned clinical pharmacology studies and ensuring overall scientific accountability for the designated studies Responsible (with members of Clinicians and Statisticians) for ensuring appropriate dose-finding strategies during clinical drug development that will ensure optimal doses in first in human studies and dosage regimens in patients Responsible for summarizing and interpreting results of pharmacokinetic, pharmacodynamic analyses with respect to their impact on development and clinical use of drugs During the pre-clinical stages of drug development, works with Drug Discovery team to ensure that sufficient preclinical PK/PD knowledge exists to support progression into first in man studies Accountable for ensuring that there are valid methods for measuring drug and metabolite concentrations (or any biochemical biomarkers) in human studies Coordinates with medical writers (and other team members) in the data review, analysis and reporting of the Clinical Pharmacology study Responsible, in conjunction with medical writer, for overall content and accuracy of study report before forwarding for final sign-off. Assist with internal and external dissemination of results to Development Team, Investigators etc. Provides recommendations for clinical doses and dosing algorithms (including drug interaction advice, food effects, special group dosing etc.) to the Clinical and Development teams and in regulatory documentation such as labeling Stays abreast of literature, government guidelines, internal guidance on clinical trial conduct including Good Clinical Practice and internal SOPs, regulations for specific projects to which assigned, in order to be a team resource of clinical pharmacology and therapeutics knowledge in terms of both medical background and clinical trial design Participates in multidisciplinary teams in assessing potential in-licensing opportunities, as requested by line management Acts as technical lead for specific development projects, Phase I/III and Clinical Pharmacology centric studies Manage and initiate external collaborations with leaders in clinical pharmacology and Key Opinion Leaders MINIMUM REQUIREMENTS PhD in clinical pharmacology, quantitative pharmacology, pharmacokinetics, or related field / MD/ PharmD preferred Biologics including monoclonal antibody, bispecific antibody, and antibody-drug conjugate experience is preferred Experiences in Oncology/Autoimmune disease field is preferred Proven expertise in pharmaceutical/biotech industry (8-15 years) with adequate knowledge in ICH guidelines, Good Clinical Practice applicable to Clinical Pharmacology Direct experience with clinical pharmacology summary documents required for Regulatory submissions Comprehensive understanding of worldwide clinical regulatory requirements with working knowledge of drug development process with a proven record in drug development from IND through regulatory submission and commercialization Experience in clinical development and new drug registration Mastery of statistics applied to clinical research Ability to work with pharmacometrician for PopPK modeling, E-R analysis, PBPK, and PK-PD modeling, and interpret the data to support the clinical development Good ability to interpret complex clinical data and experimental results Ability to develop network internally and externally to communicate in situations requiring special tact and diplomacy Self-motivated and self-disciplined individual with superb problem-solving and leadership skills Excellent English (writing and speaking) and excellent mastery of English medical terminology PREFERRED SKILLS AND EXPERIENCE: Knowledge of FDA, EMA and ICH guidelines and regulations Record of successful publications in the area of clinical pharmacology/pharmacometrics Comprehensive understanding of worldwide clinical regulatory requirements with working knowledge of drug development process with a proven record in drug development from IND through regulatory submission and commercialization. Prior direct interaction with regulatory agencies and advisory boards is required Candidate must demonstrate thorough understanding of principles of clinical pharmacology including clinical study design, analysis, and interpretation, and application of these approaches to drug development, guidelines in the design of clinical trials and development plans KEY COMPETENCIES: Ability to organize and work simultaneously on multiple projects Ability to work in a matrix, project-oriented environment Excellent written and oral communication skills, interpersonal/influencing skills, and ability to work in a continually changing environment Supports the success of a group being led by providing clarity, support and tools needed to excel as things change Maintains a functional, perspective and acts on the belief that solutions and plans are stronger when appropriate collaboration occurs across and beyond the organization Actively builds relationships and networks with others across and beyond HUTCHMED working constructively across organizational boundaries despite differences in interests, perspectives and need

About us ATG (Autonomous Technologies Group) is an AI lab deploying frontier reasoning systems within financial markets. Founders: Early GPU cloud (9 figure exit). Investors: Garry Tan / YC + Founder of one of the most successful quant funds, BoxGroup (Plaid, Ramp, Stripe), top-tier angels. About the Role You'll drive original research at the boundaries of AI, working on new models, algorithms, and architectures for reasoning in complex environments. Your work will shape the scientific agenda of the lab and inform everything we build. You'll have autonomy to pursue fundamental research and see your ideas deployed in real-world settings. Responsibilities Formulate and explore open questions in deep learning, reinforcement learning, and agent-based AI. Develop novel architectures, algorithms, and theoretical insights. Collaborate with engineers to implement, experiment, and iterate rapidly. Publish, present, and contribute to the broader research community. Mentor and support the next generation of technical talent. Requirements Demonstrated track record of impactful AI/ML research (e.g., papers, open-source, or novel deployments). Deep expertise in at least one of: LLMs, RL, agent-based systems, generative modeling, theory of intelligence. Strong mathematical background (probability, optimization, statistics). Proficiency in Python and modern ML frameworks (e.g., PyTorch, JAX). Ability to turn theory into robust, practical code. Up-to-date on the latest research in LLMs from reading papers, articles, or re-implementing breakthroughs. Expertise in leveraging the latest AI tools (Cursor, Claude Code, Codex, etc) to increase productivity & code output while maintaining high code quality, maintainability, and structure. Why Join ATG We're building a small, elite team. If you're excited by AI, markets, and building from first principles, we'd love to meet you. Work on AI with a massive market opportunity Early team of repeat founders backed by top investors High agency, talent dense, zero bureaucracy

COMPANY Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Our lead pipeline programs focus on two distinct inhibitors of KIF18A, a novel therapeutic target. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Volastra is also developing new techniques to understand the biology of chromosomal instability and leveraging these insights to drive forward a preclinical pipeline of therapies against innovative targets. Volastra is backed by top US and European venture firms such as Arch, Polaris, Vida, Droia, Catalio, and B Capital, alongside strategic investment from Eli Lilly. In addition to venture funding, Volastra has established partnerships with oncology leaders. Our senior leadership team is highly experienced, supported by a world-class advisory board. We are headquartered in West Harlem, New York City, within easy reach of Columbia, Cornell, Memorial Sloan Kettering, and surrounding areas. Please visit ****************** for more information. JOB DESCRIPTION: The role of Scientist of Discovery Science will report to the Senior Scientist/Senior Lab Manager in close collaboration with the Chief Scientific Officer and the rest of the Discovery Team, and work towards the successful execution of preclinical development programs. As a scientist, you will play a central role in turning foundational CIN biology into new medicines. You will design, execute, and interpret rigorous experiments that validate targets, elucidate mechanism of action, and accelerate progression from hit/lead to in vivo proof‑of‑concept. This is a bench‑forward position for a creative, self‑directed experimentalist who thrives in a fast‑moving biotech setting and loves collaborating across chemistry, biochemistry, DMPK, in vivo pharmacology, and computational biology. Volastra is a fast-paced biotech company of passionate employees, and there is ample opportunity for the ideal candidate to grow and develop with the organization. Individuals will have, from time to time, the opportunity to gain experience with projects outside their direct scope of work. Job is based in NYC and requires a minimum of 80% in office time. RESPONSIBILITIES: * Participate in key discovery workstreams from target validation through early pharmacology; design clear, decision‑driving experimental plans and timelines. * Interrogate mechanism using genetic perturbation (e.g. CRISPR/Cas9, RNAi), rescue, pathway mapping, and combination studies aligned with CIN biology. * Develop and optimize cellular assays to quantify phenotype and mechanism. * Build translationally relevant target‑engagement and PD assays to enable SAR and inform dose/PK-PD modeling for in vivo studies. * Track record of successfully managing external projects with CRO's from scoping to final data delivery * Work effectively with colleagues across the team to participate in adjacent discovery-related efforts * Provide clear updates to Discovery, Preclinical, and Leadership; write technical reports, support patent filings, and prepare data packages for milestones. REQUIREMENTS: * PhD in Molecular/Cell Biology, Biochemistry, Cancer Biology, Pharmacology or related field (or MS/BS with commensurate depth of industry experience). * 5+ years of hands-on lab experience with a range of relevant research techniques including cell-based assays and molecular biology. In vivo mouse experience is strongly preferred * Understanding of the drug development process from target identification to marketing authorization is strongly encouraged * Excellent communication, organizational, and problem-solving skills * Ability to collaborate well with team members PREFERRED EXPERIENCE: * Direct experience in CIN‑relevant biology (mitosis, microtubules/kinetochore function, replication stress, DNA‑damage response) or image‑based phenotyping * In vivo oncology familiarity (xenograft/PDX syngeneic models), PK/PD thinking, and translational biomarker awareness for discovery‑to‑development continuity. Salary Range: Approximately $130,000 - $150,000 which may vary depending on qualifications, experience, and ultimate leveling. Leveling outside of that stated may be considered for exceptional candidates on a case-by-case basis.

Immunai is an engineering-first platform company aiming to improve therapeutic decision-making throughout the drug discovery and development process. We are mapping the immune system at unprecedented scale and granularity and applying machine learning to this massive clinico-immune database, in order to generate novel insights into disease pathology for our partners - pharma companies and research institutes. We provide a comprehensive, end-to-end solution - from data generation and curation to therapeutics development, that continuously supports and validates the capabilities of our platform. As drug development is becoming increasingly inefficient, our ultimate goal is to help bring breakthrough medicines to patients as quickly and successfully as possible. Immunai is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. About the role: This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills. Location: New York City (On-site role) What will you do? * Augment efforts of teams using a wide range of techniques including, but not limited to immune cell isolation and processing from human specimens, cell cultures and in vitro model systems * Domain expert with single cell genomics methods, and proven experience of innovation in this field (sample optimization, protocol development). * Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware * Maintenance of a complete, accurate, and timely electronic record of all experiments using an informatics management system. * Active participation in cross-functional team meetings and effective communication with other members of the lab, computational biology, and software team * Expected to deliver impactful presentations to other colleagues including senior leadership Requirements Required qualifications: * 4-6 years of experience in Molecular Biology or Immunology; * MS with 2-4 years relevant experience, PhD with 1+ years of post-PhD experience is preferred. * Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes. Additionally, familiarity with high-throughput, automated single cell profiling workflows is preferred. * Experience working with tissue samples, including single cell dissociation. * Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage * Familiarity with high throughput lab data management (e.g. Benchling) * Strong analytical skills, problem solving ability, and innovation aptitude required * Must be willing to discover and learn new software and technology applications quickly * Must have strong attention to detail and an ability to multitask * Ability to collaborate closely with interdisciplinary individuals from a broad range of backgrounds * Ability to work independently with minimal supervision * Ability to work successfully in a fast-paced environment * Excellent interpersonal skills and ability to effectively work as part of a team are essential * Excellent organization and time management skills Desired personal traits: * You want to make an impact on humankind * You prioritize "We" over "I" * You enjoy getting things done and striving for excellence * You collaborate effectively with people of diverse backgrounds and cultures * You have a growth mindset * You are candid, authentic, and transparent Compensation: This position offers a salary typically between $105,000 - $140,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills. * Please note that when you apply for a position at Immunai, your application will be processed via our recruitment platform SparkHire. You can read more about how we process personal data here: ***************************************

Job Title: Scientist II- Immunology Anvia Therapeutics is a dynamic and innovative biotech company dedicated to developing small molecule inhibitors targeted at treating inflammatory and autoimmune diseases. We foster a collaborative environment where scientific excellence and creativity drive our mission to develop impactful medicines. Job Summary We are seeking a highly motivated immunology Scientist to drive hypothesis-driven in vitro immunology research in a fast-paced and innovative drug discovery environment. The successful candidate will design, develop, and execute complex cellular assay systems, including primary human immune cells, patient-derived samples, and disease-relevant cell lines to support immune pharmacology and mechanism-of-action (MoA) studies across inflammatory disease programs such as IBD, rheumatoid arthritis, and dermal inflammation. Responsibilities Key Responsibilities Design and execute hypothesis-driven cellular assays to support immune pharmacology, target validation, and MoA studies. Develop, optimize, and validate complex in vitro assay systems using primary immune cells, patient-derived samples, and disease-relevant or engineered cell lines. Perform functional immune assays including cell activation, proliferation, cytokine production, signaling, and cytotoxicity, using both primary and cell-line-based systems. Contribute to immune pharmacology assessments, including compound potency, pathway modulation, selectivity, and translational relevance. Apply a strong mechanistic understanding of immune and inflammatory signaling pathways to guide assay design and data interpretation. Utilize flow cytometry, ELISA/MSD/other cytokine/chemokine profiling techniques, protein- and signaling-based assays, and related techniques to generate high-quality, reproducible data. Analyze, interpret, and clearly communicate experimental results to project and leadership teams. Troubleshoot and refine experimental systems to improve robustness, scalability, and biological relevance. Maintain accurate experimental records using electronic laboratory notebooks. Collaborate closely with lead discovery, chemistry, translational, and external partners to advance program milestones. Stay current with emerging immunology technologies and incorporate innovative methodologies where appropriate. Qualifications Required Qualifications PhD in Immunology, Biology, Biotechnology, Molecular Biology, or a related field with 2+ years of relevant experience. Hands-on experience developing and executing complex cellular assays using primary immune cells, patient-derived samples, and cell line-based systems. Experience working with functional immune readouts, including flow cytometry-based phenotyping and signaling assays, and cytokine measurement (ELISA/MSD/other). Demonstrated expertise in protein-level analysis of signaling pathways, including Western blotting and related biochemical techniques used to assess pathway activation, inhibition, and mechanism of action. Strong understanding of cell signaling pathways relevant to immune and inflammatory biology. Proven ability to independently design experiments, troubleshoot assays, and manage multiple priorities. Proficiency with data analysis and visualization tools (e.g., GraphPad Prism, FlowJo, Excel). Excellent written and verbal communication skills. Preferred Qualifications Experience supporting immune pharmacology and MoA characterization in early drug discovery. Background in inflammatory or autoimmune disease biology (IBD, RA, dermatology preferred). Familiarity with assay validation, quantitative potency assessment and translational biomarker analysis/ identification. Experience working in a fast-paced, innovative biotech environment. Why Join Us? Be part of a passionate team making a difference in biotech innovation. Collaborative and dynamic work environment. Hands-on experience with state-of-the-art technologies. Opportunities for professional development and advancement. Competitive compensation and benefits. The salary range for this position is $115,000-$150,000 per year. The actual compensation offered will be based on factors such as relevant experience, education, and skills. In addition to base salary, we offer a comprehensive benefits package, including health insurance, paid time off, and retirement plan options. Anvia Therapeutics is an equal opportunity employer. We do not discriminate against any employee or applicant for employment because of race, creed (religion), color, national origin, sex (including gender identity and sexual orientation), age, disability, marital status, citizenship status, military status, genetic information, or any other characteristic protected by federal, state, or local law. Our employment decisions are based on merit, qualifications, and business needs. We are committed to providing a work environment free from discrimination, harassment, and retaliation, and we undertake affirmative action efforts to promote equal opportunity for all employees and applicants. #LI-DNI

At Inductive Bio we're tackling the challenge of making drug discovery more efficient. Chemists spend countless hours combining data, expertise, and intuition to create new molecules that are effective, safe, and work well in the human body. It's a slow, complex process, and the patients are the ones left waiting. At Inductive Bio, we're building an intuitive, collaborative platform, powered by state-of-the-art AI to help accelerate this process. Our platform is already being used on dozens of active drug discovery programs, and adoption is rapidly growing. We are backed by leading investors at the intersection of technology and biotechnology, and our team includes world-class technology and drug discovery experts. After achieving quick adoption via word-of-mouth, we are now expanding our capabilities to build state-of-the-art in silico models for toxicity prediction. We are seeking a senior Toxicologist to serve as our primary subject matter expert in toxicology, with an initial focus on liver and cardiac safety. In this role, you will help shape our scientific offering, ensure that our models are rigorously validated, and guide us toward solutions that have meaningful impact in real-world drug discovery programs. What you'll do: Serve as Inductive Bio's lead subject matter expert in toxicology, with a focus on liver and cardiac safety Guide the development of in silico toxicity models, ensuring scientific rigor, biological relevance, and translational utility Provide toxicology consulting support for partner programs Define the scientific standards, benchmarks, and validation approaches that underpin our toxicology offerings Collaborate with internal machine learning and chemistry experts to translate toxicological principles into predictive models Provide expert input into customer engagements, building credibility and helping to shape solutions tailored to partner needs Stay current on the evolving regulatory, scientific, and technological landscape in preclinical toxicology, bringing insights back to the team Contribute to external scientific presence, including publications, presentations, and conference participation Who you are: PhD in toxicology, pharmacology, or a closely related discipline 15+ years of experience in drug discovery or development with deep expertise in toxicology (preferably in both preclinical and translational contexts) Strong expertise in hepatotoxicity and cardiotoxicity, with familiarity across additional organ systems a plus Proven track record of applying toxicology insights to support decision-making in drug discovery or development programs Excellent communication and presentation skills, with the ability to explain complex concepts to both scientific and non-scientific audiences Experience interacting with regulatory authorities and knowledge of FDA/EMA/ICH guidance a strong plus Collaborative, pragmatic, and entrepreneurial-comfortable working across disciplines in a fast-moving startup environment Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast-growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.

Scientist II, Immuno-Oncology FUNCTIONAL AREA: REPORTS TO: Team Leader EXEMPT/NON-EXEMPT In the Immuno-Oncology team, we are looking for an enthusiastic, inventive and team-oriented scientist to join us in the creation cutting-edge cellular treatments for cancer and other serious diseases. We are looking for colleagues with a strong background in one or multiple areas including: Immuno-Oncology, Oncology or Immunology, and who possess strong expertise in T-cell biology, intricate multicolor flow cytometry, and in vivo mouse models. The ideal candidate would have a remarkable scientific record, excellent communication and interpersonal abilities, be passionate about scientific research, and excel at pushing boundaries for innovation. We value candidates who are adept at problem-solving and approach difficulties with optimism. The chosen individual will join a dynamic, creative and goal-oriented atmosphere dedicated to making impactful advances in the way we treat disease. Responsibilities Responsibilities include, but are not limited to: Develop innovative adoptive cell therapies to treat cancer or other serious diseases. Design, execute, and analyze in vitro experiments (some examples include engineering of CAR T-cells, cytotox, ELISA, proliferation assays, flow cytometry analysis, cell culture). Design, execute and analyze in vivo preclinical studies (some examples of procedures include tumor implantation, adoptive cell therapy administration, mice dosing through different administration routes, tumor monitoring, blood collection and multiple tissue analysis). Efficiently and clearly present and communicate scientific data to the team, cross-functionally and at external meetings. Pro-actively suggest and evaluate innovative cell engineering solutions and develop new assays to enhance the company's intellectual portfolio and contribute to peer-reviewed publications. Stay up to date with external scientific research from academic and industry institutions. Keep timely detailed documentation of experiments. Effectively plan and manage projects and deliverables to meet deadlines. Foster cross-functional collaborations and train other colleagues. Prioritize company objectives and work towards shared success. Other duties as necessary to ensure the daily operations of the lab and support the team. Core Competencies Keen eye for detail, exceptional problem-solving abilities, and a commitment to producing robust and high-quality scientific data for internal/external reports, publications and IND-enabling studies Strong scientific creativity and analytical thinking skills. Curiosity and drive to initiate and advance programs to treat diverse important diseases. Excellent written, oral and interpersonal communication skills. Capable of adhering to SOP and develop new protocols. Works well autonomously and collaboratively with other team members and cross-functionally. Flexibility and ability to adapt positively to a dynamic environment with changing priorities. Pro-active, transparent and adaptable team-player with a professional demeanor who works well under pressure. Comfortable operating in a fast-paced, small-midsized company environment. Requirements PhD in oncology, immunology, or equivalent (minimum of 3 years of experience after PhD in related role). Experience in human T-cell biology, immuno-oncology and knowledge in cell engineering technologies. Hands on experience and troubleshooting proficiency in immunology assays including immune cell isolation, multicolor flow cytometry, immune cell and cytokine profiling assays using conventional and next-generation analytical methods. Demonstrated experience designing and executing mouse tumor model experiments including mouse handling (injections- IV, SC, IP- and organ dissection). Excellent abilities to analyze and synthesize data for different audiences and report types while supporting decision-making processes. Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired. Basic knowledge of gene editing and next-generation sequencing technologies is a plus. Experience in working in matrixed environments and in project management is desired. Strong record of scientific publications and demonstrated scientific curiosity. Willingness to quickly adapt, innovate, discover new approaches, collaborate and support the team towards shared company goals. Candidates should be authorized to work in the U.S., preferably without the need for current, or future, sponsorship. Role is onsite and based in New York, NY Physical Requirements Sedentary - primarily involves sitting and/or standing. Laboratory work performed within a BSL1 and BSL2 environments. Communicates with others daily to exchange information. Salary Range (105,000 to 115,000 USD), dependent on skills and experience

Accrete is a dynamic and innovative company focused on transforming the future of artificial intelligence. We specialize in creating advanced AI solutions that turn complex data into actionable insights, driving real-world impact for businesses and government organizations. Our team thrives on creativity and collaboration, working together to push the boundaries of AI technology. At the core of our offerings are our AI agents, designed to autonomously analyze data, generate insights, and make intelligent recommendations. These agents help businesses streamline operations, improve decision-making, and also empower government entities to enhance security, intelligence, and operational efficiency Role Overview We are looking for an Applied Scientist who can bridge cutting-edge research with production-grade systems. You'll work closely with engineering, product, and our domain experts to design, prototype, and deploy models that power Accrete's next-generation AI products. This role is ideal for someone who thrives in an applied research environment, shipping models that materially improve product capabilities. What You'll Do Design, prototype, and evaluate new machine learning and NLP models-LLMs, retrieval models, agents, and multimodal models. Conduct applied research to improve model accuracy, robustness, interpretability, and efficiency. Collaborate with engineers to transition research prototypes into scalable, production-ready systems. Work cross-functionally with product managers, forward-deployed engineers, and subject-matter experts to understand real-world constraints and use cases. Own experiments end-to-end: hypothesis generation, dataset creation, experimentation, evaluation, and delivery. Stay current with the latest AI/ML research and assess opportunities to integrate state-of-the-art methods into Accrete's platform. Contribute to internal research initiatives and help define scientific strategy. Required Qualifications 3+ years of experience as an Applied Scientist, Machine Learning Engineer, Research Scientist, or similar role. Strong expertise in machine learning, NLP, information retrieval, or deep learning. Proficiency in Python and common ML frameworks (PyTorch preferred). Experience designing experiments, building datasets, and evaluating model performance. Ability to translate research ideas into practical solutions under real-world constraints. Strong communication skills and the ability to work collaboratively with cross-functional teams. Preferred Qualifications Advanced degree (MS or PhD) in Computer Science, Machine Learning, Applied Mathematics, or a related field. Experience with LLMs, embeddings, agents, or knowledge extraction systems. Experience building ML solutions that run in production environments. Familiarity with cloud infrastructure, MLOps, or Kubernetes. Experience in information extraction, summarization, or reasoning models. Background working with government data, intelligence workflows, or highly regulated environments (nice-to-have). What We Look For Curiosity and a desire to explore new research directions. A product mindset-someone who enjoys building things that solve real customer problems. Comfort working in a fast-paced, rapidly evolving startup environment. Collaborative, humble, and mission-driven. Salary Range: 160k-200k The salary range provided reflects the estimated compensation for this role based on the expected qualifications and experience level. The final offer may vary depending on factors such as skills, experience, and alignment with role requirements. Core Values & Expectations: Impact You take full ownership and accountability for your work, consistently seeing projects through from inception to completion with a strong bias for action. Proactively identifying challenges, you drive solutions rather than waiting for direction, and hold yourself and others to the highest standards for delivering results. With strategic thinking and a problem-solving mindset, you make informed decisions leveraging data and expertise, always looking for ways to improve processes, optimize workflows, and enhance outcomes beyond your immediate responsibilities. Collaboration You work seamlessly across teams, prioritizing shared goals and team success over individual credit. Engaged listening and open, candid communication are at the heart of your approach, ensuring alignment and synergy throughout the organization. You value diverse perspectives, seeking input from others to drive better results. By treating colleagues with respect and professionalism, you help build a culture of trust, supporting each other through challenges, celebrating successes, and constructively addressing conflicts to strengthen relationships and improve outcomes. Passion for AI & Innovation You are deeply excited about the transformative potential of AI and committed to contributing to a company shaping the future of work. With curiosity and a growth mindset, you continuously seek to learn, adapt, and stay at the forefront of new developments. Your enthusiasm for innovation drives you to explore new ideas, challenge the status quo, and find creative solutions that deliver meaningful impact. You approach your work with energy and a desire to advance both technology and the way we work. Company Benefits Competitive Salary: Aligned with experience and market standards Comprehensive Insurance: Health, dental, and vision coverage for you and your family 401(k) Plan: Build your financial future with our retirement savings plan Flexible PTO & Hybrid Work: Take time off when needed and enjoy remote flexibility per company guidelines Growth & Development: Access professional learning opportunities and career advancement support Onsite Perks: Enjoy catered lunches, snacks, and a fully stocked kitchen Team Bonding: Company-sponsored happy hours and social events to connect and unwind

Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the mission to reduce friction everywhere in healthcare. Our LLM-powered platform is solving chart review once and for all, across use cases. For health systems, our first product dramatically accelerates clinical registry abstraction in areas ranging from surgery and cardiology, to oncology. Our long term vision is for our AI layer to safely transform patient care and minimize unnecessary heartbreak. Layer Health's diverse founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We're seeking outstanding hires to join our team as early members. This is an opportunity to contribute to a high-impact, collaborative, mission-driven team, and help define the next stage of growth for Layer Health. Together, we will create the AI layer that will redefine healthcare for the better. Here's a collection of articles about our product, mission, recent funding round, etc. Job Description We're hiring an exceptional ML scientist. In this role, you will be responsible for pioneering innovative machine learning techniques to advance our fundamental clinical machine learning and large language model efforts. You can expect to: Design and implement state-of-the-art machine learning techniques to advance Layer Health's research agenda (in areas such as information extraction, multimodal reasoning, and summarization). Propose new agentic methods that tackle fundamental NLP and ML challenges such as modeling over multiple documents, long contexts, multiple modalities, and with limited or noisy labels Build foundation models to power the future of clinical information extraction & synthesis, from training through inference. Stay up-to-date and actively engage with cutting-edge research in NLP, generative AI, and clinical machine learning. Collaborate with the broader engineering team to ship performant products that meet user needs. Cultivate and foster a robust and thoughtful R&D culture that drives the company forward. We look for: Exceptional methodological research background and experience, including but not limited to: A PhD in computer science/applied mathematics or equivalent research experience, specializing in natural language processing and machine learning. High-impact, early-author publications at top peer-reviewed ML journals/conferences. Demonstrated record of delivering real-world impact from start to finish- with the ability to design, develop, and ship innovations. Strong programming skills and fluency with modern machine learning/LLM stacks (deep learning libraries e.g. PyTorch, Jax). Past experience in training/inference of foundation models (billions of parameters, distributed training, familiarity with state-of-the-art techniques). A strong communicator who thrives in a customer-focused, fast-paced environment. An excited and adaptable team player who wants to disrupt the healthcare industry with AI/ML, alongside an awesome team. Past experience in healthcare of life sciences is a plus, but not required. We are a Boston-based company, and expect employees to meet regularly in-person in Boston (employees from Boston, NYC, or east coast are welcome). Expected compensation range for this role is $200,000-250,000, in addition to stock options. Compensation is dependent on experience, overall fit to our role, and candidate location. Expected compensation ranges for this role may change over time. If your compensation requirement is greater than our posted salary ranges, please still consider applying to our role. We will make a determination as to whether an exception can be made. If you are excited about this role, we encourage you to apply even if you don't feel that you meet every single requirement. We're eager to meet people that believe in our mission and can contribute to our team in a variety of ways. We welcome diverse perspectives, rigorous thinking, and fearlessness in challenging the status quo. Layer Health is committed to fostering an environment of inclusion that is free from discrimination. We are an Equal Opportunity Employer where employment is decided on the basis of qualifications, merit, and business need. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected Veteran status, or any other characteristic protected by law. Join us and help us transform healthcare with AI.

The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Scientist - Senior Associate on the AI Research team, you will conduct end-to-end research typically within a specialized focus area and collaborate on multiple research projects with internal and external researchers and applied engineering teams. Your output will result in high-impact business applications, open-source software, patents and/or publications in AI/ML conferences and journals. The goal of J.P. Morgan AI Research is to explore and advance cutting-edge research in AI, including ML as well as related fields like Cryptography, impacting clients and businesses, with a team of experts located in New York, London, Madrid, Paris, and the Bay Area. Conducting AI research in financial services offers unique and exciting opportunities for impact to both J.P. Morgan and the broader AI community. Job responsibilities Conduct end-to-end research typically within Agents, Reasoning (including AI heuristic search, planning, scheduling, constraint reasoning), Knowledge representation and Learning Collaborate with internal and external researchers and with applied engineering teams Engage in all aspects of the research lifecycle such as formulating problems, gathering data, generating hypotheses, developing models and algorithms, conducting experiments, synthesizing results, building prototype applications and communicating the significance of your research Produce outputs that lead to high-impact business applications, open source software, patents and/or publications in top AI/ML conferences and journals Participate in relevant top-tier academic conferences to broaden the impact of your contributions Required qualifications, capabilities, and skills PhD in Computer Science or related field or a MS in Computer Science or related field with at least 3 years of experience in the field Research publications in prominent AI venues; e.g., conferences, journals Expertise in one or more specialized areas of relevance e.g., heuristic search, planning, agent-based architectures, hybrid systems, knowledge representation, … Strong expertise in synthetic data, generative AI, differential privacy, uncertainty quantification, LLM alignment and behavior modeling using RL, bandit techniques, watermarking. time-series, reasoning and foundational models Proficiency with rapid prototyping and disciplined software development processes Expertise in software engineering within collaborative project settings Preferred qualifications, capabilities, and skills Extensive programming skills in Python (required), Java or C++ (optional) Interest in problems related to the financial services domain (specific past experience in the domain is not required)

The Applied Innovation of AI (AI2) team is an elite machine learning group strategically located within the Chief Technology Office of JP Morgan Chase. AI2 tackle business critical priorities using innovative machine learning techniques and technologies with a focus on machine learning for Software, Cybersecurity and Technology Infrastructure. The team partners closely with stakeholders in these areas to execute projects that require machine learning development to support JPMC businesses as they grow. Strategically positioned in the Chief Technology Office, our work spans across Cybersecurity, Global Technology Infrastructure and the Software Development Lifecycle (SDLC). With this unparalleled access to technology groups in the firm, the role offers a unique opportunity to explore novel and complex challenges that could profoundly transform how the bank operates. As a Machine Learning Scientist, you will apply sophisticated machine learning methods to a wide variety of complex tasks including data mining and exploratory data analysis and visualisation, text understanding and embedding, anomaly detection in time series and log data, large language models (LLMs) and generative AI for technology use-cases, reinforcement learning and recommendation systems. You must excel in working in a highly collaborative environment together with the business, technologists and control partners to deploy solutions into production. You must also have a passion for machine learning and invest independent time towards learning, researching and experimenting with new innovations in the field. You must have solid expertise in Deep Learning with hands-on implementation experience and possess strong analytical thinking, a deep desire to learn and be highly motivated. Job Responsibilities Research and explore new machine learning methods through independent study, attending industry-leading conferences and experimentation Develop state-of-the art machine learning models to solve real-world problems and apply it to complex business critical problems in Cybersecurity, Software and Technology Infrastructure Collaborate with multiple partner teams in Cybersecurity, Software and Technology Infrastructure to deploy solutions into production Drive firmwide initiatives by developing large-scale frameworks to accelerate the application of machine learning models across different areas of the business Contribute to reusable code and components that are shared internally and also externally Required qualifications, capabilities and skills PhD in a quantitative discipline (e.g. Computer Science, Electrical Engineering, Mathematics, Operations Research, Optimization, or Data Science.) with 1 year experience Or Masters with 2 years of industry or research experience in the field. Hands-on experience and solid understanding of machine learning and deep learning methods Extensive experience with machine learning and deep learning toolkits (e.g.: TensorFlow, PyTorch, NumPy, Scikit-Learn, Pandas) Extensive experience with large language models (LLMs) and accompanying tools & techniques in the LLM ecosystem (e.g. LangChain, LangGraph, Vector databases, opensource Models, RAG, Agentic Systems & Workflows, LLM fine-tuning) Scientific thinking and the ability to invent Ability to design experiments and training frameworks, and to outline and evaluate intrinsic and extrinsic metrics for model performance aligned with business goals Experience with big data and scalable model training Solid written and spoken communication to effectively communicate technical concepts and results to both technical and business audiences Curious, hardworking and detail-oriented, and motivated by complex analytical problems Ability to work both independently and in highly collaborative team environments Preferred qualifications, capabilities and skills Strong background in Mathematics and Statistics Familiarity with the financial services industries Experience with A/B experimentation and data/metric-driven product development Experience with cloud-native deployment in a large scale distributed environment Published research in areas of Machine Learning, Deep Learning or Reinforcement Learning at a major conference or journal Ability to develop and debug production-quality code Familiarity with continuous integration models and unit test development

R&D Partners is seeking to hire a Scientist Ops- 1st Shift in Branchburg, NJ. Your main responsibilities as a Scientist Ops- 1st Shift: The successful candidate will conduct non-routine laboratory experiments designed to implement new technologies or investigate basic scientific questions relevant to customer complaints/technical issues with Polymerase Chain Reaction (PCR) assays and reagents and project responsibilities. Designs, plans and executes assigned investigation/trouble shooting activities, research/development related experiments/projects and applying scientific knowledge and accumulated experience to complete projects. Need to accurately record information and make sound scientific interpretation of experimental results, which are to be communicated to non-scientific audience through investigational reports and verbal presentations. The successful candidate should have deductive reasoning and critical thinking in their tasks as they attempt to enact change to processes and reinforce new methodology in solving problems. Establish priorities, create and maintain time frames, and report status of project's progress toward established project goals and deadlines. What we are looking for in a Scientist Ops- 1st Shift: Bachelor s degree or equivalent combination of education and work experience in Biological science. 3 years of relevant industry experience or general laboratory experience. Why Choose R&D Partners? As an employee, you have access to a comprehensive benefits package including: Medical insurance PPO, HMO & HSA Dental & Vision insurance 401k plan Employee Assistance Program Long-term disability Weekly payroll Expense reimbursement Online timecard approval Pay Scale: $58,240 - $93,600 ( Dependent on Experience) R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies. R&D Partners is an equal-opportunity employer.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description Cross project Clinical Pharmacology support for late stage clinical programs. Contribute to the design and coordination of pharmacokinetic / DMPK related elements for clinical projects. Identify potential project hurdles, suggest solutions and establish contingency plans. Represent Oncology Clinical Pharmacology (OCP) on clinical trial teams to support early or late stage clinical programs. Contribute expert input into key pre-clinical and clinical, and regulatory documents including clinical study protocols, clinical study reports, modeling reports, investigator brochures, IND / IMPD's and NDA's within agreed timelines, and meeting all regulatory requirements under frequent guidance from manager. Facilitate constructive collaboration within drug development teams (GPTs, etc) and with other internal partners (e.g. DMPK, Toxicology, Formulations, Drug Regulatory Affairs, Clinical Development). Work with a senior colleague or supervisor to define and update as appropriate the PK, PK/PD, DMPK, biopharmaceutical and pharmacometric requirements in the OCP and/or pre-clinical project development plans. Monitor timelines, objectives and, as appropriate, budgets. Ensure accuracy of project and activity progress in company tracking tools (e.g., Succeed, ModTracker). Assure rapid and effective communication of high quality data and results to project teams with support of manager. Follow internal processes, adhere to Client and project specific standards and, when required, adhere to Health Authority requirements (SOPs, Master Analysis Plan, GCP, and regulatory guidelines). Contribute to writing and updating new processes and standards for OCP. Contribute to and participates in OCP or project sub-teams. Coordinates with appropriate subteam members and/or prepare summary documentation. Maintain and enhance technical and drug development expertise (e.g. training courses, external meeting attendance). Help conduct training / study sessions within OCP and for other line functions. Contribute to meetings with external parties including investigators and outside experts. Languages: Fluent English (oral and written) Experience/Professional requirement: 1. 0-10 years of relevant academic, industry, or government experience 2. Proficiency with pharmacometric tools (e.g., WinNonlin, SAS, NONMEM, Trial Simulator, GastroPlus, SymCyp). 3. Knowledge of related disciplines (e.g., DMPK, biostatistics, toxicology, regulatory) in the drug development process. 4. Ability to work as part of a cross functional team in a highly dynamic, matrixed, project-team environment. 5. Strong oral and written communication skills. 6. Strong organizational and project skills. 7. Critical thinking and problem solving skills. Qualifications Education:. Ph.D. in a relevant discipline, Pharm D. with appropriate post-doctoral training, or equivalent experience. Additional Information Best Regards, Akriti Gupta ************** Morristown, NJ 07960

Join us and celebrate the beauty of human experience. Create for happier, healthier lives, with love for nature. Together, with passion and creativity, we deliver food innovations, craft inspired fragrances and develop beauty and wellbeing solutions. There's much to learn and many to learn from, with more than 16,000 employees around the world to explore ideas and ambitions with. Every day, your talent, your innovative spirit, and your determination will shape our future, making a positive difference on billions of people. Every essence of you enriches our world. We are Givaudan. Human by nature. Senior Toxicologist - Specialist in Developmental and Reproductive Toxicology (DART) You will play an important role as our in-house expert on Developmental and Reproductive Toxicology (DART), strengthening our safety science capabilities, ensuring compliance with global regulatory standards, and contributing to innovative approaches for reproductive and developmental safety assessment under a regulatory landscape that is quickly evolving. You will help create product safety documentation for registration with relevant authorities and provide scientific guidance to all partners. Reporting to the Head of Fragrance Human Safety Sciences, you will be based close to one of our Regulatory Fragrance Offices (Paris, Ashford, or Ridgedale (NJ, USA)), working four days onsite and one from home each week. Main Responsibilities Product Safety & Scientific Leadership Be Givaudan's internal expert for Developmental and Reproductive Toxicology (DART). Provide excellence in human health safety to demonstrate the safe use of our ingredients and products to customers and regulators. Plan, coordinate, and oversee pre-clinical DART studies following OECD, ICH, and other regulatory guidelines. Define and monitor safety testing strategies in compliance with REACH, TSCA, and other global regulations. Work with CROs on study monitoring, reporting, and strategic planning; past study director experience in reputed toxicology CROs is a strong asset. Contribute to the development and application of New Approach Methodologies (NAMs) for reproductive and developmental toxicity testing (in vitro, in silico, and alternative models). Regulatory Policy & Advocacy Provide Givaudan management with expert guidance on complex regulatory and safety issues. Interpret scientific and technical data affecting Givaudan's global regulatory toxicology activities. Represent Givaudan on industry safety committees and contribute to trade association initiatives. Product Documentation & Registration Lead efforts to obtain relevant toxicology or regulatory data needed to support product registrations. Act as the liaison between R&D project teams and product safety functions. You - Your Profile Includes PhD required in toxicology, biochemistry, chemistry, or related scientific discipline. 10-15 years of expertise in pre-clinical studies within the field of Developmental and Reproductive Toxicology/Biology. Demonstrated track record in planning, coordinating, and accomplishing DART studies following OECD, ICH, and other regulatory guidelines. Past experience as a DART-specialized study director in a reputed toxicology testing CRO Familiarity with digital fundamentals (AI, machine learning for advanced data analysis). Familiarity with global regulatory frameworks relevant to reproductive and developmental toxicity. Fluent in English (spoken and written). For US: Salary expectation based on technical experience: 120,000 - 160,000 usd Location: The position will be based on the candidate's current location (UK, France, or US) Our Benefits: Annual bonus. Medical insurance coverage. Career Development Opportunities with access to many virtual learning sessions International working environment #LI-Onsite #ZR At Givaudan, you contribute to delightful taste and scent experiences that touch people's lives. You work within an inspiring teamwork culture - where you can thrive, collaborate and learn from other talented and passionate people across disciplines, regions and divisions. Every essence of you enriches our world. Diversity drives innovation and creates closer connections with our employees, customers and partners. Givaudan embraces diversity and is committed to building an inclusive environment where everyone impacts our world.

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: Hybrid In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.Pfizer compensation structures and benefit packages are aligned based on the location of hire. Relocation assistance may be available based on business needs and/or eligibility. Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Medical

Drug discovery is a prediction problem. Scientists design molecules that they predict will be potent, safe, and readily absorbed into the body, but ultimately lab experiments must be run to know whether these predictions are accurate. Each one of these experiments can take weeks or months to run, and as a result it costs millions of dollars and takes years to design a molecule that is ready for testing in humans. At Inductive Bio, we're using AI to build in silico models that can more accurately predict how molecules will behave in experiments. By predicting complex molecular properties directly from the molecular structure, our platform helps scientists make better decisions faster-ultimately bringing safer, higher-quality medicines to patients more quickly. We are enabled by a unique and growing proprietary data set, and we are already applying our methods to dozens of active drug discovery programs. Backed by leading investors at the intersection of biotechnology and technology and advised by renowned experts in drug discovery, we are growing rapidly and poised to make a major impact in drug discovery. We are seeking Machine Learning Scientists to join our talented, ambitious, and kind team. You'll have the opportunity to innovate on methods, work with leading drug discovery scientists, and apply your work immediately to drug programs at some of the most innovative biotechs in the world. As an early machine learning scientist at a rapidly-growing startup, you'll have the opportunity for high impact while learning and growing with the company. What you'll do: Develop machine learning models to predict molecular properties from chemical structures Develop novel algorithms for generating ideas for new molecules Build agents that can synthesize complex information from drug programs and apply that information strategically toward molecular optimization Get your hands dirty by diving deep into our unique, proprietary dataset to iterate on modeling ideas and improve model performance Collaborate closely with chemists and software engineers to integrate models into our software platform, which is used by drug discovery scientists across the industry Build and optimize scalable infrastructure for model training, deployment, and monitoring Engage directly with our scientific users, incorporating their feedback into the product Contribute meaningfully to product strategy and company direction Who you are: You have 4+ years of experience as a Machine Learning Scientist, Machine Learning Engineer, Data Scientist, or similar role You have expertise in machine learning fundamentals, deep learning architectures, and evaluation approaches You are proficient in standard Python-based ML frameworks (e.g. PyTorch, TensorFlow, scikit-learn) You are comfortable writing high-quality, reusable code and productionizing models for serving in the cloud You are excited to dive deep into the science and practice of drug discovery You have exceptional written and oral communication skills Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.

The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Senior Associate in J.P. Morgan AI Research, you will work on novel techniques, tools, and frameworks to model and solve complex large-scale problems, collaborating with experts in Trustworthy AI and contributing to high-impact business applications and the broader AI community. Your role involves formulating problems, generating hypotheses, developing algorithms and models, conducting experiments, and communicating research significance. Your output will result in publications, high-impact business applications, open-source software, and patents. Job responsibilities Work on multiple research projects in collaboration with internal and external researchers and applied engineering teams Formulate problems, generate hypotheses, develop new algorithms and models, conduct experiments, synthesize results, gather data, build prototypes, and communicate research significance Contribute to publications in AI/ML conferences and journals, high-impact business applications, open-source software, and patents Participate in relevant top-tier academic conferences, organize workshops, and engage with the AI research community to broaden the impact of your contributions Required qualifications, capabilities, and skills PhD in Computer Science, Statistics, Engineering, or related fields Programming skills in Python Proficient understanding of fundamental AI and ML techniques (e.g., A*, regularization) Practical experience with statistical data analysis and experimental design Curiosity, creativity, resourcefulness, and a collaborative spirit Effective verbal and written communication skills with technical and business audiences Demonstrated ability to work on multi-disciplinary teams with diverse backgrounds Interest in problems related to the financial services domain Preferred qualifications, capabilities, and skills Research publications in prominent AI/ML or Software Engineering venues (e.g., conferences, journals) Strong expertise in Trustworthy AI topics like explainability, safety, robustness, fairness Hands-on experience in developing and using multimodal foundation models Practical experience with ML platforms such as TensorFlow/Keras, PyTorch Comfort with rapid prototyping and disciplined software development processes Practical software engineering experience in collaborative project settings

You will lead and coordinate the development of multiple studies of novel biological and small molecules for first in human (FIH), proof of mechanism (POM), early signs of efficacy (ESOE) and proof of concept (POC) studies in Oncology. You will work in close collaboration with the Global Development Lead (GDL)and members of the development team to establish, lead, coordinate, and execute the early oncology clinical development plan(s). You will lead the development of the clinical protocol and participate as an individual contributor on clinical teams with Pfizer development operations and the project team, to meet enrollment and study delivery timelines. You will also work with other functional disciples to ensure the full scope and remit of Oncology Early Stage Development (OESD) is represented as need within clinical study teams (e.g. Research Units, Biostatistics, Clinical Pharmacology, Precision Medicine, and Digital Medicine). POSITION RESPONSIBILITIES Partner closely with the Global Development Lead (GDL) in the execution of the clinical development strategy and plan for the assigned molecule(s)/indication(s) Responsible for scientific leadership and execution of clinical studies and delivering on innovative clinical study designs, high quality trial execution, safety assessment and interpretation of clinical study results Support execution for all FIH programs through proof-of concept Set the clinical data review strategy, ensure quality data and conduct review of emerging clinical data and trends; review and query data; present and discusse relevant data to appropriate teams, governance bodies, and other internal and external stakeholders Conduct data review, analysis and interpretation of clinical trials data together with the GDL, Clinical Safety, and Biostatistics. Serve as technical resource for clinical issues raised by internal and external collaborators, investigators, consultants and contractors Support and assist in the development of publications, abstracts, and presentations May sit on project teams to support clinical development implementation and contribution to key development milestones, e.g. start-up and delivery of ESoE and PoC trials. Participate in project teams to help implement clinical development and contribute to key milestones (e.g., start-up and delivery of early signs of efficacy [ESoE] and POC trials). Lead the preparation of clinical protocols and support other critical documents including clinical development plans, INDs, annual reports, clinical study reports (CSRs), investigator brochures, statistical analysis plans, and regulatory documents. Foster a transparent environment that builds strong partnerships and mutual trust among teams and therapeutic areas. Coordinate with other clinical research activities within Oncology Research Development (ORD) and the broader Worldwide Research and Development (WRD) organization. Develop effective collaborations with key internal and external partners, such as project leaders, research units, biostatistics, regulatory affairs, clinical pharmacology, human genetics, translational oncology, precision medicine, and development operations. Partner with Translational Oncology and Biomarker teams to ensure biomarker plans are integrated into relevant programs for early efficacy signs and POC, as well as patient stratification. Establish and support relationships with external experts, consultants, key opinion leaders, regulators, and investigator networks to integrate the latest clinical thinking and guidelines into development plans and study designs, as well as manage study recruitment, analysis, interpretation, and presentation of results. Maintain up-to-date knowledge of scientific and clinical literature in relevant therapeutic areas, including key clinical development issues. Perform other duties as assigned related to clinical programs. Support functional area priorities and contribute to or lead departmental initiatives as requested. MINIMUM QUALIFICATIONS / KEY SKILLS Relevant PhD or PharmD and a minimum of 5 years of experience in a similar role in industry/CRO, OR MS and a minimum of 7 years of experience in a similar role in industry/CRO, OR BA/BS and a minimum of 10 years of experience in a similar role in industry/CRO Clinical Research experience in Phase 1 in Oncology, on the side of the sponsor leading studies Experience in or strong understanding of Oncology Drug Development especially in Early Development Strong knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Strong scientific writing skills and communication skills (written and verbal) Clinical document writing experience (e.g., protocol, ICD, IB, IND), as well as understanding complex data analysis. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working with and solid understanding of related disciplines, e.g., Clinical Operations, Data Management, Safety, Biostatistics, Regulatory, Study Management, Pre-Clinical, Pharmacology, Quality Assurance. Experience building consensus and driving change across all levels of the organization including senior management. Data listing review experience Critical thinker, with experience working collaboratively in a fast-paced, team-based matrix environment as well as working independently when appropriate Experience performing complex data analyses using JReview, SpotFire, SOCs-PRO or other similar platform PREFERRED QUALIFICATION Experience leading a team Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. PHYSICAL/MENTAL REQUIREMENTS Perform complex data analysis NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS 5-10% Travel Work Location Assignment: Hybrid The annual base salary for this position ranges from $169,700.00 to $282,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. 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