Senior principal scientist jobs in Pittsburgh, PA

Job TitleSenior Clinical Development ScientistJob Description Senior Clinical Development Scientist The Senior Clinical Development Scientist will lead the design and implementation of clinical trials for regulatory compliance and strategic alignment, while collaborating with multidisciplinary teams to develop cutting-edge strategies for new product introductions and market initiatives. Your role: Communicate with stakeholders to ensure project clarity and alignment. Facilitate informed decision-making and foster collaborative relationships. Analyze clinical trial protocols and studies. Ensure regulatory adherence and recommend protocol optimizations. Collaborate with multidisciplinary teams to develop clinical development and market access strategies for NPI projects and post-market initiatives. Craft compliant Clinical Evaluation Reports (CERs), Clinical Study Reports (CSRs), and clinical regulatory submissions. Use standard tools, procedures, templates, and external regulations. Troubleshoot complex clinical data collection and analysis issues. Ensure data integrity, accuracy, and consistency across studies. Assess and analyze clinical study data. Support dissemination through abstracts, white papers, and peer-reviewed publications. You're the right fit if: You've acquired 5+ years of relevant clinical development/clinical research experience (medical device industry experience required). You have experience independently authoring Clinical Evaluation Reports, Clinical Evaluation Plans, Clinical Study Protocols, and Post Market Clinical documentation. Human Subjects Research experience is a must. Your skills include strong knowledge of regulatory compliance and relevant standards, medical writing, and clinical research. You have a strong understanding of GCP (Good Clinical Practice), and human subjects protection. You have a MD or PhD in a relevant field (preferred) or equivalent combination of education and experience. You must be able to successfully perform the following minimum Physical, Cognitive and Environmental job requirements with or without accommodation for this position. You're an analytical problem solver, with a strong ability to execute initiatives in a cross-functional capacity working with multidisciplinary teams. Exhibits a strong ability to advocate for ethical standards and evidence-based practices. How we work together We believe that we are better together than apart. For our office-based teams, this means working in-person at least 3 days per week. Onsite roles require full-time presence in the company's facilities. Field roles are most effectively done outside of the company's main facilities, generally at the customers' or suppliers' locations. This is an office-based role. About Philips We are a health technology company. We built our entire company around the belief that every human matters, and we won't stop until everybody everywhere has access to the quality healthcare that we all deserve. Do the work of your life to help improve the lives of others. Learn more about our business. Discover our rich and exciting history. Learn more about our purpose. Learn more about our culture. Philips Transparency Details The pay range for this position in Pittsburgh, PA is $129,375 to $207,000 The pay range for this position in Plymouth, MN is $135,844 to $217,350. The pay range for this position in Cambridge, MA, San Diego, CA or Bothell, WA is $144,900 to $231,840. The actual base pay offered may vary within the posted ranges depending on multiple factors including job-related knowledge/skills, experience, business needs, geographical location, and internal equity. In addition, other compensation, such as an annual incentive bonus, sales commission or long-term incentives may be offered. Employees are eligible to participate in our comprehensive Philips Total Rewards benefits program, which includes a generous PTO, 401k (up to 7% match), HSA (with company contribution), stock purchase plan, education reimbursement and much more. Details about our benefits can be found here. At Philips, it is not typical for an individual to be hired at or near the top end of the range for their role and compensation decisions are dependent upon the facts and circumstances of each case. Additional Information US work authorization is a precondition of employment. The company will not consider candidates who require sponsorship for a work-authorized visa, now or in the future. Company relocation benefits will not be provided for this position. For this position, you must reside in or within commuting distance to posted location(s). #LI-PH1 This requisition is expected to stay active for 45 days but may close earlier if a successful candidate is selected or business necessity dictates. Interested candidates are encouraged to apply as soon as possible to ensure consideration. Philips is an Equal Employment and Opportunity Employer including Disability/Vets and maintains a drug-free workplace.

Arconic is currently in search of Staff Scientist, Optimization & Data Analytics to join our Arconic Technology Team based in New Kensington, PA At Arconic, we take pride in our work and our innovative products and technologies that advance sustainable solutions for a better world. We strive to create a safe, inclusive, and collaborative workplace with competitive benefits, development opportunities and a culture that values and rewards employees on all levels of the organization. Job Summary: The Staff Scientist, Optimization and Data Analytics is responsible for developing and supporting optimization, scheduling, and analytics applications across Arconic's processes including casting, rolling, extrusion, etc. This role is part of our Research & Development team and will provide technical expertise to support operations and lead multi-disciplinary projects focused on optimization of aluminum forming/fabrication processes.

. . . . . NEW OPPORTUNITY Associate Director | Principal Scientist Pharmacology Immuno-Oncology Research This is your opportunity to join a start-up Immuno-Oncology Company and to be a significant contributor as they GROW! Do your skills include the following: Managing, developing, mentoring junior scientists? Overseeing CRO | external resources activity? Advancing assets from candidate selection to preclinical development to IND? PDX models, Humanized models, Xenograft models, etc.? Biomarker discovery | Biomarker strategy? To learn more about this exciting opportunity . . . . Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************

The Senior Clinical Development Scientist will lead the design and implementation of clinical trials for regulatory compliance and strategic alignment, while collaborating with multidisciplinary teams to develop cutting-edge strategies for new product introductions and market initiatives. Your role: * Communicate with stakeholders to ensure project clarity and alignment. Facilitate informed decision-making and foster collaborative relationships. * Analyze clinical trial protocols and studies. Ensure regulatory adherence and recommend protocol optimizations. * Collaborate with multidisciplinary teams to develop clinical development and market access strategies for NPI projects and post-market initiatives. * Craft compliant Clinical Evaluation Reports (CERs), Clinical Study Reports (CSRs), and clinical regulatory submissions. Use standard tools, procedures, templates, and external regulations. * Troubleshoot complex clinical data collection and analysis issues. Ensure data integrity, accuracy, and consistency across studies. * Assess and analyze clinical study data. Support dissemination through abstracts, white papers, and peer-reviewed publications. You're the right fit if: * You've acquired 5+ years of relevant clinical development/clinical research experience (medical device industry experience required). You have experience independently authoring Clinical Evaluation Reports, Clinical Evaluation Plans, Clinical Study Protocols, and Post Market Clinical documentation. Human Subjects Research experience is a must. * Your skills include strong knowledge of regulatory compliance and relevant standards, medical writing, and clinical research. You have a strong understanding of GCP (Good Clinical Practice), and human subjects protection. * You have a MD or PhD in a relevant field (preferred) or equivalent combination of education and experience. * You must be able to successfully perform the following minimum Physical, Cognitive and Environmental job requirements with or without accommodation for this position. * You're an analytical problem solver, with a strong ability to execute initiatives in a cross-functional capacity working with multidisciplinary teams. Exhibits a strong ability to advocate for ethical standards and evidence-based practices. How we work together We believe that we are better together than apart. For our office-based teams, this means working in-person at least 3 days per week. Onsite roles require full-time presence in the company's facilities. Field roles are most effectively done outside of the company's main facilities, generally at the customers' or suppliers' locations. This is an office-based role. About Philips We are a health technology company. We built our entire company around the belief that every human matters, and we won't stop until everybody everywhere has access to the quality healthcare that we all deserve. Do the work of your life to help improve the lives of others. * Learn more about our business. * Discover our rich and exciting history. * Learn more about our purpose. * Learn more about our culture. Philips Transparency Details The pay range for this position in Pittsburgh, PA is $129,375 to $207,000 The pay range for this position in Plymouth, MN is $135,844 to $217,350. The pay range for this position in Cambridge, MA, San Diego, CA or Bothell, WA is $144,900 to $231,840. The actual base pay offered may vary within the posted ranges depending on multiple factors including job-related knowledge/skills, experience, business needs, geographical location, and internal equity. In addition, other compensation, such as an annual incentive bonus, sales commission or long-term incentives may be offered. Employees are eligible to participate in our comprehensive Philips Total Rewards benefits program, which includes a generous PTO, 401k (up to 7% match), HSA (with company contribution), stock purchase plan, education reimbursement and much more. Details about our benefits can be found here. At Philips, it is not typical for an individual to be hired at or near the top end of the range for their role and compensation decisions are dependent upon the facts and circumstances of each case. Additional Information US work authorization is a precondition of employment. The company will not consider candidates who require sponsorship for a work-authorized visa, now or in the future. Company relocation benefits will not be provided for this position. For this position, you must reside in or within commuting distance to posted location(s). #LI-PH1 This requisition is expected to stay active for 45 days but may close earlier if a successful candidate is selected or business necessity dictates. Interested candidates are encouraged to apply as soon as possible to ensure consideration. Philips is an Equal Employment and Opportunity Employer including Disability/Vets and maintains a drug-free workplace.

The Sr. Food Scientist will be technically sound, creative and will be responsible for formulation and processing support of new customer business across multiple plants within the Tandem Foods network. This role has a heavy emphasis on production support, and the Sr. Food Scientist must be comfortable and confident supporting a production environment. A successful candidate will lead by providing technical support both at the benchtop and plant level. This position will focus on owning new product pipeline projects and formulation initiatives with attention on building relationships with new customers and working collaboratively across all functions of the organization. Key Responsibilities Lead formulation development and processing support for new and existing customer projects across multiple manufacturing sites. Expected to be the technical expert on R&D subject matter to support production through the commercialization process and beyond to provide ongoing support to plant operations Troubleshoot challenges in formulation and process that are mindful of safety and costs while providing timely and effective solutions Collaborate with cross-functional teams including Sales, Operations, and Food Safety and Quality to align technical solutions with business objectives Work closely with customers to ensure product expectations are achieved and relationships are strengthened Plan, execute, and summarize plant trials for internal and external customers Preparation and execution of all related technical and business documentation Maintain accurate documentation of formulations, test results, and project progress Interact with ingredient suppliers to onboard new raw materials and trouble shoot formulation challenges Creative thinker with the ability to translate into stable product formulation Create new snack products utilizing Genesis as a formulation tool Present new formulation concepts to our sales team for external customer presentations Stay abreast of new ingredient developments as well as processing and equipment advances applying them to enhance project work Participate in sensory evaluation to drive decisions that are best for our customers Ability to taste and screen ingredients and finished products without dietary limitations Key Competencies Creative Thinking: Thinks outside the box, contributes ideas for new product concepts with the ability to bring them to life Customer Focus: Understands and monitors the needs of internal and external customers Adaptable / Flexible: Open to change in response to new information, different or unexpected circumstances Cross-Functional Collaboration: Ability to work in a dynamic team environment Self-Starter: Takes initiative in developing programs to conform with set standards, focusing on continual improvement Problem-Solving: Prevents and solves issues from a technical prospective, understand and mitigates problems, recognizes cause and effect relationships between functions Project and Time Management: Plans tasks and deliverables accurately, prioritizes tasks and adapts as needed and is responsive to requests and accountable for actions Qualifications Bachelor's degree in food science or another science-based field 5-8 Years' experience in a product development position preferably in a manufacturing environment Strong understanding of food formulation, ingredient functionality, and processing technologies Effective interpersonal and written communication skills with the ability to build relationships cross-functionally and externally Strong working knowledge of the food industry Excellent problem-solving, organizational and prioritization skills Experience with formulating protein bars, baked products and / or confections Proficient in MS Office suite including Excel and PowerPoint Working knowledge of Genesis Familiarity with regulatory requirements (FDA, etc.) Willingness to travel to manufacturing sites and customer locations as needed Work Environment This role works in office, R&D lab, and manufacturing floor environments Evening and weekend work may be required on an as needed basis 20-25% travel 85% production support 15% R&D benchtop work (formulation review /concept creation) Responsible for keeping workspace clean and organized (wash lab utensils and maintain ingredient inventory) Responsible for R&D shipments (UPS /FedEx) RequiredPreferredJob Industries Warehouse & Production

THE OPPORTUNITY: Molecular Diagnostic Assay Development Scientist About Captis Diagnostics: Captis Diagnostics is a biotechnology Start-up company committed to transforming cancer care through non-invasive technologies. We specialize in leveraging extracellular vesicles (EVs)/exosomes to develop next-generation cancer diagnostic tools for improved patient outcomes. Position Summary: Captis Diagnostics is seeking a Molecular Diagnostic Assay Development Scientist to lead and support the design, development, and optimization of molecular diagnostic assays. The successful candidate will play a key role in driving innovation in our assay pipeline, with responsibilities spanning from experimental planning to data interpretation. This is a full-time, on-site position based in Pittsburgh, PA, reporting to the Project Lead. Key Responsibilities: Design, develop, and optimize high-throughput sequencing-based assays (e.g., Illumina, PacBio, Nanopore) to identify clinically relevant genetic changes. Lead the development and validation of droplet digital PCR (dd PCR), qPCR, and RT-qPCR assays for sensitive and specific detection of rare genetic changes. Analyze, interpret, and present experimental results to cross-functional teams; contribute to technical reports, protocols, and scientific publications. Troubleshoot assay performance and implement improvements to enhance sensitivity, specificity, and reproducibility. Collaborate with team members on R&D initiatives and help translate research findings into clinical assay formats. Manage reagent procurement and inventory, maintain organized lab records, and help ensure compliance with internal SOPs and quality standards. Qualifications: Ph.D. in Molecular Biology, Genetics, Biochemistry, or a related field; or M.S. with at least 2-3 years of relevant industry or academic experience. Demonstrated experience in molecular diagnostics assay development, particularly PCR and/or sequencing-based methods. Hands-on expertise with dd PCR, qPCR, RT-qPCR, and nucleic acid extraction. Strong data analysis and troubleshooting skills. Experience working in a fast-paced research or product development environment. Excellent organizational, communication, and teamwork skills. Self-motivated, detail-oriented, and committed to high-quality scientific work. Preferred Qualifications: Experience with exosome/EV isolation and characterization. Familiarity with liquid biopsy technologies and oncology biomarkers. Prior involvement in CLIA or CAP-compliant assay development is a plus. To Apply: Please submit a cover letter describing your interest in this position and your desired salary range, along with your resume/CV, to Dr. Simon He at [email protected]. Please include "Molecular Diagnostic Assay Development Scientist" in the subject line.

Title: Mass Spectrometry Senior Scientist Type: 6-month contract to hire Hours: 8AM-5PM Start: December Join in establishing a state-of-the-art, multi-omics facility to support research and clinical translational programs in multiple OMICS disciplines, including proteomics, metabolomics, and lipidomics. We are seeking a highly skilled and motivated Senior Scientist for the Mass Spectrometry Facility to oversee day-to-day operations while remaining actively involved in sample processing and instrument analysis. Interested in learning more? Please apply today! Responsibilities + Act as the go-to subject matter expert for mass spectrometry, including custom method development, automation initiatives, and troubleshooting to enhance analytical precision and continuous improvements in mass spectrometry-based omics. + Ideal candidate should be able to identify erroneous results and execute rapid fault-diagnosis, root-cause identification, and corrective action on mass spectrometers. + Perform hands-on work in all aspects of LC-MS/MS workflows, including sample preparation, method development and setup, and data acquisition. + Train, mentor, and supervise technical staff; foster a culture of precision, accountability, and teamwork. + Collaborate with researchers to design, optimize, and execute mass spectrometry based studies. + Ideal candidate should have experience operating, maintaining, calibrating, and troubleshooting mass spectrometers. + Maintain accurate records of instrument performance, sample tracking, and results within the Laboratory Information Management System (LIMS). + Proven practice in using samples, controls, and standards to create robust reference materials to accurately review and analyze output data. Requirements + PhD or Master's degree with 7 years of experience in biochemistry, analytical chemistry, or a related field. + Minimum of 7 years' experience operating and maintaining mass spectrometers. + Preferably 3 + years in a core facility environment working with Thermo Mass Spectrometry instrumentation, with demostrated experience in method development. + Proven experience in LC-MS sample preparation, data acquisition, and troubleshooting. + Demonstrated ability to manage staff and workflow while maintaining personal engagement in laboratory operations. + Strong organizational, problem-solving, and communication skills. + A proactive mindset, able to adapt and perform under pressure. Specifically, demonstrate ability to operate in a fast-paced, high-throughput core facility environment. + Driven and detail-focused scientist who thrives in a collaborative and high-throughput lab environment. System One, and its subsidiaries including Joulé, ALTA IT Services, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law. #M3 #LI-DS1 Ref: #558-Scientific System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

At Skild AI, we are building the world's first general purpose robotic intelligence that is robust and adapts to unseen scenarios without failing. We believe massive scale through data-driven machine learning is the key to unlocking these capabilities for the widespread deployment of robots within society. Our team consists of individuals with varying levels of experience and backgrounds, from new graduates to domain experts. Relevant industry experience is important, but ultimately less so than your demonstrated abilities and attitude. We are looking for passionate individuals who are eager to explore uncharted waters and contribute to our innovative projects. Position Overview We are looking for Research Scientists to lead the effort in developing the next generation of techniques to advance the capabilities of our robotic systems. We are looking for people with proven expertise in machine learning and/or robotics, who are passionate about pushing the boundaries of what is possible. You will collaborate with a team of talented researchers and engineers, and enhance our cohesive research strategy, driving ongoing innovation and technological advancements within the company. The ideal candidate will have a track record of discovering fundamental, scalable solutions, and a passion for seeing their research transform into impactful applications. Responsibilities Develop new algorithms and methods for training general-purpose robot foundation models. Conduct cutting edge research across multiple disciplines (Perception, Robotics, RL / IL, Machine Learning, etc.). Work with large scale systems and large-scale model training. Preferred Qualifications PhD degree in Computer Science, Robotics, Engineering or a related field, or equivalent practical experience. Multiple years of experience in conducting research. Proficiency in Python and at least one deep learning library such as PyTorch, TensorFlow, JAX, etc. Publications at top-tier ML, robotics, or CV conferences (e.g., NeurIPS, ICML, ICLR, CoRL, RSS, ICRA, CVPR, ECCV, ICCV). Deep technical knowledge, and research experience in deep learning, reinforcement learning, robotics, or computer vision. Deep understanding of state-of-the-art machine learning techniques and models. Experience working with robot systems. Experience working with large-scale model training and systems. Base Salary Range $100,000 - $300,000 USD

Purpose BlueSphere Bio is seeking an exceptionally talented and highly motivated Senior/Principal Scientist with Immunology and Oncology background to join our group to develop T-cell therapies for cancer using our TCXpress and NEOXpress platform technologies. This position's primary role is to develop an effective process using our proprietary technologies to identify tumor-specific T cell receptors and their expression in autologous or allogeneic primary human T cells. The ideal candidate will have an extensive Immunology and/or Oncology background either in academia or industry with proven records on advancing projects in the forms of publications or patents. The position is supervising two research associates and one lab tech. Excellent communication and leadership skills are required as the candidate is expected to serve as a project leader interacting with several functions within BSB and managing external collaborations. Duties and Responsibilities Lead research and development of BSB's neoantigen computational prediction methods Utilize broad technical expertise in T cell immunology, molecular biology, and cell pharmacology to advance candidate T cell therapies to clinical development. Further develop and enhance BSB's position by filing for patents and establishing innovative technologies. Participate in formulating the overall BSB internal program strategy and lead/assist with external partnerships and collaborations with Academia and Industry. Support technology transfer to clinical development. Clearly communicate, present, and defend critical TA activities to upper management for successful program progression. Define critical path activities to complete essential projects required to meet key corporate objectives in a timely fashion. Manage and mentor current and future TA scientists. Other duties as assigned Qualifications and Work Experience Ph.D. or master with more than three (3) years of experience in bioinformatics, computational biology, systems biology, or a related discipline with a strong track record of publications/patent Experience developing and/or using NGS-based software (e.g., variant calling, gene expression, epigenetic analyses, single-cell sequencing approaches) in an HPC environment. Plus, if he or she used the software in cancer or immunology research contexts. Strong molecular biology knowledge in conjunction with NGS-data analysis Fluency in SAM, BAM, VCF file format specifications, and other standard bioinformatic formats Understanding protein structure and/or experience in structure modeling is a plus. Proficiency with the following: Use of Linux in a cluster-computing environment Experience applying statistical fundamentals to biological datasets Python, R, C/C++, JavaScript, and current web technology. Experience integrating diverse NGS and non-NGS data sets to identify cancer drivers, predictive biomarkers, or mechanistic hypotheses Experience with mining public data sets, such as TCGA, GTEx, and CCLE Demonstrated ability to formulate and test hypotheses by designing and implementing novel computational approaches for detecting neoantigens Capacity to prioritize and work independently to complete tasks and advance projects with supervision Strong written and verbal skills; ability to translate and communicate complex information and concepts for scientists of diverse backgrounds Positive and collaborative attitude; ability to work effectively with internal and external collaborators and multidisciplinary teams composed of scientists and non-scientists to translate emerging research to guide internal programs Physical and Mental Requirements You will be expected to occasionally (1% to 20% of the time): You will be expected to frequently (21% to 50% of the time): Lift objects from one level to another (30 lbs. or less) Carry objects (30 lbs. or less) Walk around the facility on foot Stand on your feet Travel up to 25% You will be expected to constantly (at least 51% of the time): Sit in a normal seated position

Job Description Who We Are EHS Support is a specialty environmental consulting firm that provides solutions to complex environmental, health, and safety challenges across a range of market sectors and industries. With experts located throughout the United States, Canada, Australia, New Zealand, the United Kingdom, and South Africa, we form long-lasting partnerships with our clients through a culture of excellence, innovation, work ethic, and integrity. We focus on hiring and retaining talented, motivated people who enjoy collaborating with and delivering value to our clients. Our team does more than identify problems- we provide solutions. Job Overview This Senior Scientist opportunity is for a flexible and self-motivated individual that is willing to learn and grow as part of a team while providing environmental and ecological risk assessment expertise to projects within the Sediment and Risk Assessment (SRA) and Remediation (REM) service lines at EHS Support. As a Senior Scientist, you will be joining a high-performance team of risk assessors, toxicologists, ecologists, scientists, and engineers that is focused on providing high-quality technical and strategic solutions to a variety of clients. Your primary responsibilities in the Senior Scientist position will include managing and leading multi-media environmental and ecological investigations for routine and complex scenarios under federal, state, and international programs. You will also be responsible for managing a team of talented professionals, cultivating client relationships, and providing mentorship to junior team members. Essential Responsibilities Lead and manage routine to complex projects with strict adherence to schedule, budget, and quality. Lead the design and implementation of environmental and ecological investigations conducted as part of remedial investigations, particularly contaminated sediment investigations, ensuring compliance with regulatory requirements under CERCLA, RCRA, or state programs. Lead design, conduct, and oversight of data analyses in support of investigation objectives. Lead preparation of high-quality technical deliverables and presentations for effective communication of investigation findings. Advocate for the technical findings and conclusions of investigations and negotiate with state and federal regulators. Stay abreast of industry trends, advancements, and emerging issues. Participate in technical conferences or work groups to advance novel approaches. Implement and uphold rigorous quality assurance processes to maintain the highest standards in investigation methodologies and reporting. Oversee multiple projects simultaneously, ensuring timely and successful completion within budget constraints. Collaborate with cross-functional teams to integrate investigations into broader environmental impact assessments and natural resource damage assessments (NRDA). Specific Experience and Skills 12+ years of experience in consulting and environmental and ecological assessment for remedial investigation, with a strong track record of successful project outcomes and management. Proven leadership and management skills, with experience in mentoring and developing staff. Excellent written and verbal communication skills. Exceptional interpersonal skills. Strong knowledge of regulations and guidance for remedial investigation and risk assessment under state and federal programs (e.g., RCRA, CERCLA). Strong analytical and problem-solving abilities. Education and Licenses Master's degree in biology, chemistry, ecology, environmental science, natural resources, toxicology or a related field. Benefits Generous Vacation Policy Health Benefits (medical, dental, vision) 401k w/matching options Short- & Long-Term Disability Life Insurance Sick Time Bonus Opportunities Our Principles Strive for excellence, always Be open, honest, and direct Assume good intentions Trust coworkers, leadership, and clients Listen to learn Be accountable for our work Foster teamwork Demonstrate integrity Take pride in one's work Live your personal values Provide a safe and health work environment that promotes wellness Have fun! EHS Support is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

This position is in the laboratory of Mei-Chuan Ko, PhD, which is part of the Translational Neuroscience Program in the Department of Psychiatry, University of Pittsburgh School of Medicine and UPMC Western Psychiatric Hospital. The lab uses nonhuman primates to research substance use disorders, sensory processing (pain and itch), and the efficacy/therapeutic window of pharmacological treatment. This position is grant funded. Responsibilities: * Work closely with the Principal Investigator (PI) to manage ongoing non-human primate (NHP) studies and support the planning and initiation of new projects. * Oversee the preparation and administration of experimental compounds in NHPs. * Provide training and guidance to new staff on NHP handling as well as proper use of laboratory equipment and instruments. * Assist with specimen collection and related study procedures. * Perform data analysis for RNAscope, telemetry, and EEG experiments. * Collaborate with the PI on manuscript preparation, publication efforts, and grant applications. * Prepare, interpret, and present research findings to internal teams and external audiences. * PHD in Psychology, Neuroscience, Counseling, Sociology, or related research field with a minimum of three years of work experience in a research project and/or related clinical setting is required. * Familiarity with computers and common software packages required. * Working knowledge of research methodology required. * Prior supervisory experience preferred. Licensure, Certifications, and Clearances: * Act 34 UPMC is an Equal Opportunity Employer/Disability/Veteran

Penn Environmental & Remediation, Inc. has an immediate opening for a Wetlands Scientist to work out of our Pittsburgh, PA office. The successful candidate will be responsible for conducting environmental analysis and performing field work related to wetland and stream delineation, habitat assessments, and evaluation of environmental impacts associated with project development. Various tasks include supporting the siting and permitting of renewable, utility, energy, and infrastructure projects, including pipelines and related facilities, transmission lines, substations, and renewable energy projects. The ideal candidate must have practical knowledge or experience with environmental laws and regulations, which are the framework for the development of energy infrastructure development. Knowledge or experience with permit applications, wetland and stream impacts, rare, threatened and endangered species consultation, land use, overhead and underground utility construction methodologies, water quality and stormwater management specific to energy and land development projects is desired. The position offers great potential for professional growth in a collaborative work environment. Duties and Responsibilities: Conduct field work consisting of wetland delineations and habitat assessments, but may include assistance on site investigations and remediation projects. Participate in linear energy planning/routing/siting studies. Write survey reports and prepare permit applications for federal and/or state environmental permits, including U.S. Army Corps of Engineers Section 404 and Section 10, Pennsylvania Department of Environmental Protection Chapters 102 and 105, and rare, threatened, and endangered species coordination. Coordinate with and attend meetings with local, state, and federal agencies. Self-motivated with an attention and commitment to timely completion of high-quality work. Emergency response oversight for spills and releases Analysis and management of data Technical report writing Support other lines of business, including but not limited to: remediation, soil and water sampling, infiltration testing, etc. General field skills and knowledge of various field / sampling equipment Strong technical writing capability and computer and communication skills Self-motivated Knowledge in the following areas a plus: Phase I/II environmental assessments, geologic evaluations and field investigations, soil and ground water sampling, PADEP regulatory programs (including Chapter 102, Chapter 105, and Act 2). Talent is the essence of meeting our client's objectives, goals, and challenges. If this sounds like a fit for you, we'd love to have that first discussion of you joining our team. Minimum Qualifications: BS/BA in environmental studies, planning, natural resources, engineering, or related field. 4+ years of experience within the environmental consulting and/or regulatory field. Prior wetland delineation and field work experience, with, or ability to obtain WPIT or PWS certification. Highly motivated with a client-oriented focus. Ability to work independently, manage multiple tasks concurrently, work in a team environment with inter-disciplinary professionals, and problem solve and think creatively. Excellent written and oral interpersonal communication skills. An advanced understanding or existing experience in the environmental analyses principals associated with the siting and permitting facilities. Willingness to travel (primarily within Pennsylvania) 20-30% of time. Exercise responsible, safe, and ethical decision-making regarding company funds, resources, and conduct and adhere to policies and procedures. Penn E&R, Inc. is an Equal Employment Opportunity employer. We adhere to a policy of making employment decisions without regards to race, color, religion, sex, age, disability or any other protected categories. It is our intention that all qualified applicants be given an equal opportunity and that selection decisions be based on job-related factors.

Job DescriptionAre you ready to help shape the future of BioPharmaceutical analytical services? As a Senior Scientist - BioPharm at RJ Lee Group, you'll combine your scientific expertise with leadership and innovation to drive the growth of a dynamic, high-impact business line. Your unique ideas, technical skills, and collaborative spirit will help us expand our services, exceed client expectations, and make a real difference in the biotechnology, pharmaceutical, and biomedical industries. We believe diverse perspectives fuel better science, and we're excited to see what you'll bring. About the Job You'll work hands-on with state-of-the-art analytical technologies while leading in client engagement, regulatory compliance, and project execution. This is a high-visibility opportunity where you'll help define best practices, influence business growth, and collaborate across teams to deliver high-quality, compliant analytical services. This role is based at our Pittsburgh headquarters and requires a commitment to on-site work to maintain cGMP standards and laboratory excellence. At RJ Lee Group, we invest in your growth, value your contributions, and empower you to confidently lead. What You'll Do Support and expand the BioPharm analytical services division through hands-on technical work and client collaboration. Lead or contribute to method development, validation studies, and multi-year client programs. Ensure analytical testing services meet cGMP standards and other regulatory requirements. Manage projects independently, from planning to client delivery, while collaborating across teams. Communicate technical findings clearly to both expert and non-expert stakeholders. Assist with business development activities and client engagement as needed. Foster a culture of scientific integrity, innovation, compliance, and continuous improvement. What You'll Bring Master's degree or PhD in a relevant field (e.g., Biomaterials, Organic Chemistry, Analytical Chemistry, Biochemistry, Biology). Minimum of 2 years of experience in a biopharmaceutical role (laboratory, quality assurance, project management, or related areas). Strong working knowledge of analytical techniques such as FTIR, DSC, GCMS, LCMS, and SEM. Hands-on experience working in a cGMP-regulated environment. In-depth understanding of quality assurance requirements for GMP laboratory analysis. Proven ability to manage projects independently and contribute effectively in cross-functional teams. Familiarity with the broader biopharmaceutical industry and regulatory landscape. Excellent communication skills, with an ability to translate complex technical information clearly. Preferred Qualifications Experience supporting or leading multi-year client programs or method development/validation studies. Familiarity with ISO 17025 standards, FDA regulations, and state/national accreditation processes. Previous client-facing technical roles or experience supporting business development efforts. Willingness to travel and flexibility to accommodate project demands. Why You'll Love Working at RJ Lee Group Impactful Work: Support industries where precision and compliance truly matter-biotechnology, pharmaceuticals, biomedical devices, and more. Career Growth: Access mentorship, leadership opportunities, and continuous learning in a supportive, high-expectation environment. Collaboration & Innovation: Join a passionate team of scientists, engineers, and industry specialists committed to solving real-world challenges. Top-Tier Benefits: Competitive salary packages Paid time off and holidays Medical, dental, and vision insurance Flexible medical/dependent care benefits Group life and disability insurance 401(k) savings and investment program Culture of Inclusion: We value diversity and believe every unique perspective strengthens our team and our results. About RJ Lee Group For over 40 years, RJ Lee Group has been a trusted leader in scientific consulting, laboratory testing, and materials characterization. From advanced pharmaceutical analysis to regulatory compliance consulting, we deliver rigorous data, clear insights, and actionable solutions. Our clients-from industry innovators to government agencies-count on us for technical excellence, deep experience, and a commitment to scientific integrity. At RJ Lee Group, your work matters-to your team, your clients, and the industries we serve. How to Apply Are you ready to lead, grow, and make a real impact? Apply today at RJ Lee Group Careers. Equal Opportunity Employer RJ Lee Group, Inc. is proud to be an Equal Opportunity Employer. We celebrate diverse backgrounds, experiences, and perspectives, and are committed to building an inclusive, supportive workplace for all. Powered by JazzHR PtRAuwf5v9

In XRCIA, we aspire to achieve a vision of social presence in VR and AR where people are enabled to interact with each other across distances in a way that is indistinguishable from in-person interactions. We are looking for exceptional researchers who are excited about designing and implementing models that transform partial human information into realistic VR representations. As a Research Scientist, you will pursue research, and work with other Computer Vision and Machine Learning Researchers and Engineers to build the foundations of social presence technology. You will be exposed to facilities, algorithms, and data that are years ahead of anything else in existence today. We want people who seek both the best quality and widest reach in their work. Minimum Qualifications * Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience * Currently has or is in the process of obtaining a PhD degree and/or postdoctoral assignment in the field of computer vision, computer graphics, machine learning or a related field * Currently has, or is in the process of obtaining a Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience. Degree must be completed prior to joining Meta * First author publications in computer vision, machine learning or computer graphics peer-reviewed conferences (e.g. CVPR, ECCV, ICCV, NeurIPS, ICLR, or SIGGRAPH, etc.) * Experience with realistic 3D geometry/apperance estimation/generation or motion modeling * Must obtain work authorization in country of employment at the time of hire, and maintain ongoing work authorization during employment Preferred Qualifications * Experience with generative models such as Diffusion Models, GANs or VAEs for image and geometry generation. * 3+ years of experience with prototyping algorithms in Python. * Proven track record of achieving significant research results as demonstrated by grants, fellowships and/or patents. * Demonstrated software engineer experience via an internship, work experience, coding competitions, or widely used contributions in open source repositories (e.g. GitHub). * Experience with Neural Radiance Fields, Visual Transformers or Large Language Models. Responsibilities * Develop state-of-the-art algorithms and models that can transform information deficient inputs (e.g. cameras with limited visibility, pose, text, audio) into indistinguishable-from-reality VR representations (e.g. faces, bodies, hair, clothes, motion) * Collaborate with other teams to push the research that enables mid to long-term products * Publish research results in top-tier journals and at leading international conferences About Meta Meta builds technologies that help people connect, find communities, and grow businesses. When Facebook launched in 2004, it changed the way people connect. Apps like Messenger, Instagram and WhatsApp further empowered billions around the world. Now, Meta is moving beyond 2D screens toward immersive experiences like augmented and virtual reality to help build the next evolution in social technology. People who choose to build their careers by building with us at Meta help shape a future that will take us beyond what digital connection makes possible today-beyond the constraints of screens, the limits of distance, and even the rules of physics. Equal Employment Opportunity Meta is proud to be an Equal Employment Opportunity employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, reproductive health decisions, or related medical conditions), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, genetic information, political views or activity, or other applicable legally protected characteristics. You may view our Equal Employment Opportunity notice here. Meta is committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans in our job application procedures. If you need assistance or an accommodation due to a disability, fill out the Accommodations request form.

Arconic is currently in search of a Staff Scientist, Lubrication and Tribology to join our Rolled Products North America Team based out of New Kensington, PA. At Arconic, we take pride in our work and our innovative products and technologies that advance sustainable solutions for a better world. We strive to create a safe, inclusive, and collaborative workplace with competitive benefits, development opportunities and a culture that values and rewards employees on all levels of the organization. Job Summary: The Staff Scientist, Lubrication and Tribology is responsible for developing and supporting lubricant and surface technology with application across Arconic's processes including casting, rolling, extrusion, etc. This role is part of our Research & Development team and will provide technical expertise to support operations and lead multi-disciplinary projects focused on optimization of aluminum forming/fabrication processes.

. . . . NEW OPPORTUNITY Translational Scientist: Immuno-Oncology (Title TBD) Do your skills include the following: Drug discovery and pre-clinical development? Oncology | Immuno-Oncology? PDX models, Humanized models, Xenograft models, etc.? Experience with biomarkers | | biomarker profiling | biomarker strategy? Would you like to learn more about this exciting new opportunity? Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************

BlueSphere Bio is a Pittsburgh-based immunotherapy company developing novel T-cell therapies to treat individuals diagnosed with liquid and solid tumors. The established proprietary platform technologies in Neoantigen and tumor-specific TCR discoveries have provided a rich foundation for various TCR-T cell therapy pipelines and cancer vaccines to address unmet medical need in both blood and solid tumors. The Research & Development (R&D) organization at BlueSphere Bio aims to accelerate the translation of innovative research discoveries into new cancer therapeutic medicines through the collaboration with CMC, clinical and business development functions. Job Description We are seeking an Scientist I/Associate Scientist to join BlueSphere Bio's T-cell Receptor (TCR) Discovery team. The incumbent will use state-of-the-art instrumentation and techniques for the identification of TCRs that recognize minor histocompatibility antigens, as well as tumor-associated antigens and neoantigens. Additionally, she/he will work with a group of individuals developing a high-throughput platform that is able to isolate and identify rare antigen-specific T-cells from healthy and patient donor samples. Candidates interested in expanding their knowledge and gaining experience in cell-based (TCR-T) cancer therapies and drug discovery are highly-encouraged to apply. Duties and Responsibilities may include Process, characterize, and coordinate the genotyping of primary human blood/PBMC samples Apply high-throughput cell culture techniques for establishing co-cultures of primary T-cells with antigen-presenting cells Transduce and/or electroporate antigen-presenting cells with lentivirus or plasmid constructs Analyze T-cells and T-cell receptor function via flow cytometry Perform molecular biology techniques as the project requires for the cloning and detailed characterization of TCRs Develop assays for high-throughput screening of T-cells and TCR-antigen reactivity Maintain accurate sample and laboratory records Organize and conduct assigned studies with a high-degree of independence and attention to detail Present scientific results to peers and management during regularly scheduled lab meetings Required & Preferred Qualifications PhD in Cancer Biology, Immunology, Cell Biology, Molecular Biology, or related fields is required Hands-on research experience in an academic or industry setting is required A record of advancing projects, as evidenced by publications or patents is required In-depth knowledge of cellular biology is required Demonstrated work in cell culture techniques, including designing, setting up, and performing cell-based assays is required Experience in T-cell enrichment, expansion, and characterization is preferred Previous exposure to flow cytometry is required Experience in cell line development is required Experience in cellular transfection, lentivirus production and transduction is required Experience in assay/platform development is preferred Proficiency with analytical software packages, e.g., SnapGene, PRISM, FlowJo, and Excel is preferred The ability to adhere to timelines and milestones, in an organized manner, is required Excellent communication and presentation skills are preferred Demonstrated ability to independently identify issues and troubleshoot Physical and Mental Requirements You will be expected to occasionally (1% to 20% of the time): Climb stairs, ramps, ladders. Etc. Stoop/crouch by bending your legs or bending down/forward at the waist Reach by extending the hands/arms Lift objects from one level to another (30 lbs. or less) Carry objects (30 lbs. or less) Travel (up to 20%) You will be expected to frequently (21% to 50% of the time): Walk around the facility on foot Stand on your feet You will be expected to constantly (at least 51% of the time): Sit in a normal seated position BlueSphere Bio is an Equal Opportunity Employer (EOE) and offers employment opportunities to all qualified persons regardless of race, color, religion, sex, age, national origin or ancestry, physical or mental disability (except where physical or mental abilities are a bona fide occupational requirement), veteran status, marital status, familial status, sexual orientation, HIV-positive status, possession of the sickle cell trait, genetic characteristics, political views, and any other basis protected by federal, state or local laws.

Are you ready to help shape the future of BioPharmaceutical analytical services? As a Senior Scientist - BioPharm at RJ Lee Group, you'll combine your scientific expertise with leadership and innovation to drive the growth of a dynamic, high-impact business line. Your unique ideas, technical skills, and collaborative spirit will help us expand our services, exceed client expectations, and make a real difference in the biotechnology, pharmaceutical, and biomedical industries. We believe diverse perspectives fuel better science, and we're excited to see what you'll bring. About the Job You'll work hands-on with state-of-the-art analytical technologies while leading in client engagement, regulatory compliance, and project execution. This is a high-visibility opportunity where you'll help define best practices, influence business growth, and collaborate across teams to deliver high-quality, compliant analytical services. This role is based at our Pittsburgh headquarters and requires a commitment to on-site work to maintain cGMP standards and laboratory excellence. At RJ Lee Group, we invest in your growth, value your contributions, and empower you to confidently lead. What You'll Do Support and expand the BioPharm analytical services division through hands-on technical work and client collaboration. Lead or contribute to method development, validation studies, and multi-year client programs. Ensure analytical testing services meet cGMP standards and other regulatory requirements. Manage projects independently, from planning to client delivery, while collaborating across teams. Communicate technical findings clearly to both expert and non-expert stakeholders. Assist with business development activities and client engagement as needed. Foster a culture of scientific integrity, innovation, compliance, and continuous improvement. What You'll Bring Master's degree or PhD in a relevant field (e.g., Biomaterials, Organic Chemistry, Analytical Chemistry, Biochemistry, Biology). Minimum of 2 years of experience in a biopharmaceutical role (laboratory, quality assurance, project management, or related areas). Strong working knowledge of analytical techniques such as FTIR, DSC, GCMS, LCMS, and SEM. Hands-on experience working in a cGMP-regulated environment. In-depth understanding of quality assurance requirements for GMP laboratory analysis. Proven ability to manage projects independently and contribute effectively in cross-functional teams. Familiarity with the broader biopharmaceutical industry and regulatory landscape. Excellent communication skills, with an ability to translate complex technical information clearly. Preferred Qualifications Experience supporting or leading multi-year client programs or method development/validation studies. Familiarity with ISO 17025 standards, FDA regulations, and state/national accreditation processes. Previous client-facing technical roles or experience supporting business development efforts. Willingness to travel and flexibility to accommodate project demands. Why You'll Love Working at RJ Lee Group Impactful Work: Support industries where precision and compliance truly matter-biotechnology, pharmaceuticals, biomedical devices, and more. Career Growth: Access mentorship, leadership opportunities, and continuous learning in a supportive, high-expectation environment. Collaboration & Innovation: Join a passionate team of scientists, engineers, and industry specialists committed to solving real-world challenges. Top-Tier Benefits: Competitive salary packages Paid time off and holidays Medical, dental, and vision insurance Flexible medical/dependent care benefits Group life and disability insurance 401(k) savings and investment program Culture of Inclusion: We value diversity and believe every unique perspective strengthens our team and our results. About RJ Lee Group For over 40 years, RJ Lee Group has been a trusted leader in scientific consulting, laboratory testing, and materials characterization. From advanced pharmaceutical analysis to regulatory compliance consulting, we deliver rigorous data, clear insights, and actionable solutions. Our clients-from industry innovators to government agencies-count on us for technical excellence, deep experience, and a commitment to scientific integrity. At RJ Lee Group, your work matters-to your team, your clients, and the industries we serve. How to Apply Are you ready to lead, grow, and make a real impact? Apply today at RJ Lee Group Careers. Equal Opportunity Employer RJ Lee Group, Inc. is proud to be an Equal Opportunity Employer. We celebrate diverse backgrounds, experiences, and perspectives, and are committed to building an inclusive, supportive workplace for all.

BlueSphere Bio was founded to deploy its novel TCXpress technology to unlock the potential of personalized T cell therapy for the treatment of cancer by harnessing the unique specificity of each patient's T cells for the molecular fingerprint of each patient's cancer. Our trailblazing, proprietary TCXpress platform is an elegant, rapid approach that exploits the patient's immune defenses to attack their cancer specifically and is designed to leave normal tissues untouched, thereby reducing harmful side effects. The TCXpress platform and its implementation will deliver rapid, personalized T cell treatments for various cancer indications. Purpose The Scientist has a background in Synthetic Biology, Immunology, and Molecular biology to join our newly established group developing novel T cell products for adoptive cell-based immunotherapy of cancer. The position's primary role is in developing approaches to engineer T cell receptors in autologous or allogeneic primary human T cells. An ideal candidate will have a proven record of proficiency in Immunology and Molecular Biology. Knowledge in CRISPR/Cas9 and other non-viral gene-editing technologies is preferred. The candidate will join a diverse team with cross-functional interaction with development and discovery functions. The position requires excellent communication skills and the ability to work effectively in a goal-focused team environment. Duties and Responsibilities Establish methodologies for T cell gene modification and associated functional assays. Responsible for establishing efficient T cell receptor expression platforms in primary T cells using recombinant lentiviruses and CRISPR/ Cas9 technology Responsible for generation of high-titer recombinant lentiviruses, quality control of the lentiviral preparations, and generation of associated reagents Responsible for T cell immunology, including isolation, modification, expansion, and analysis of autologous and cryopreserved allogeneic primary T cell populations. Maintain accurate sample and laboratory records. Document activities in electronic notebook system, develop IP, publish and present in conferences Work closely with our development team to advance technology platforms and TCR candidates. Develop data packages and reports for internal corporate activities and regulatory submissions Present regularly at team meetings. Lead, train and mentor junior staff by example Other duties as assigned Qualifications and Work Experience Ph.D. in Immunology, Oncology, Molecular Biology, or related field with five years of postgraduate experience Mammalian Cell Culture: immortalized and primary adherent, and non-adherent cells T cell biology: Isolation and in vitro maintenance of PBMC, including CD4+ and CD8+ primary T cells. T cell activation, gene modification, and expansion for downstream functional assays, including TCR-dextramer binding, activation assays (proliferation, cell-based killing assays, analysis of cytokine secretion, etc.) Flow Cytometry: Strong background in multi-color flow cytometry [4 channel flow cytometry analysis preferred] of primary human immune cells and cell lines Molecular Cloning: vector design, restriction enzyme analysis of expression vectors, restriction independent cloning [In-Fusion and/or Gibson] Lentiviral technology: Understanding of LV packaging systems and LV expression vector components; experience in LV vector isolation and generation of recombinant lentivirus; lentiviral applications: transduction of immortalized and primary cells focusing on primary human PBMC and T cells Methods of non-viral gene delivery to target cells: transfection, electroporation/nucleofection, CRISPR/Cas9 with the focus on human PBMC and primary T cells Protein Biochemistry: western blotting, ELISA, isolation of proteins from mammalian cells, analytical protein purification using pull-down and immunoprecipitation techniques DNA/RNA isolation and nucleic acid technologies: PCR, RT-PCR, and Q-RTPCR; familiarity with NGS and RNA-Seq, genomic DNA PCR and Sanger sequencing; isolation of vector DNA (mini, midi, maxi, and mega preps), agarose gel electrophoresis and DNA/RNA fragment isolation from agarose gel Bacterial Culture: maintenance of bacterial cells, the transformation of the competent bacteria, isolation of vector DNA (mini, midi, maxi, and mega preps) Software: flow cytometry software, data analysis software (GraphPad Prism, Excel, etc.), Microsoft Office suite Organizational skills: experience in working in a multi-disciplinary team environment; resource management; ability to manage one's time within the individual, departmental, and corporate goals and timelines Physical and Mental Requirements You will be expected to occasionally (1% to 20% of the time): You will be expected to frequently (21% to 50% of the time): Lift objects from one level to another (30 lbs. or less) Carry objects (30 lbs. or less) Walk around the facility on foot Stand on your feet Travel up to 25% You will be expected to constantly (at least 51% of the time): Sit in a normal seated position