Senior principal scientist jobs in Revere, MA - 1,014 jobs

The role will be responsible for all operations involved with routine manufacturing and quality control testing of radiopharmaceuticals produced in Aktis' GMP laboratory (Boston, MA), including but not limited to the list below. This role will report to the Director of Clinical Trial Manufacturing. Salary Range: $136,800.00 To $189,200.00 Annually Responsibilities Manual and automated production of radiopharmaceuticals in a GMP facility QC testing of radiopharmaceuticals Execution and upkeep of the facilities' environmental monitoring program Accurate and timely preparation and completion of manufacturing and Quality control records (Batch Records, Forms, Logbooks, etc.) Process/analytical method validation for clinical manufacturing Operation and maintenance of equipment in the GMP facility Preparation of products for shipment to other sites Drafting, reviewing and updating GMP documentation including SOPs Upkeep and maintenance of inventory in the GMP Facility Maintenance of the GMP facility including assisting with radioactive waste stream management Perform contamination wipe tests and surveys Performing and maintenance of the facilities' environmental monitoring program Leading manufacturing process and analytical method qualification activities Contribute to writing CMC sections for submission to regulatory agencies Maintain KPI and internal reports Supporting external tech transfer activities Required Skills Proficient with aseptic operations and environmental monitoring Proficient with QC methodologies (HPLC, GC, MS, Gamma Spec, etc.) Proficient with assembly and interpretation of analytical data Expertise with troubleshooting analytical and production equipment High attention to detail and organizational skills to enable working in a fast-paced environment Ability to work in an ISO7 environment with full gowning Adhere to stringent cleanroom protocols and maintain a high level of hygiene Perform precise aseptic manipulations in a restrictive environment Awareness of FDA and EU GMP requirements Ability to lift 60lbs Expertise with GMP radiopharmaceutical manufacturing and quality control Minimum, B.Sc. with 10+ years or M.Sc. with 7+ years of experience in the pharma industry or equivalent research experience Comprehensive knowledge of GMP manufacturing and quality control workflows Excellent verbal, written, and organizational skills Strong desire to be part of a mission‐oriented company leading transformative change for patients Proven demonstration of transparent communication and fostering open and diverse debate Ability to work with agility and manage ambiguity Personifies positive energy and exemplifies respect #J-18808-Ljbffr

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Responsibilities Partner with our pharma clients to design, develop and execute computational research leveraging the Tempus platform to advance drug R&D programs. Become an expert in Tempus multimodal clinical and genomic data. Analyze and integrate large, diverse clinical and molecular datasets to extract insights and drive new research opportunities. Lead scientific and technical interactions with clients to co-architect solutions and projects. Become an expert in current and prospective clients' strategies, pipelines, and portfolios to identify where the Tempus platform can add value and collaborate with sales teams to realize that value. Collaborate with Research, Engineering & Data Science teams to develop and deliver innovative computational solutions. Drive continual improvement of the Tempus platform by communicating client feedback, staying ahead of research and industry trends, championing opportunities for new markets, and influencing our leadership and global account strategy teams. Work with Product and Engineering teams to streamline the workflow of computational analyses. Document, summarize, and communicate highly technical results and methods clearly to non-technical audiences. Author whitepapers and peer-reviewed manuscripts illustrating the value of multimodal analysis and AI in drug discovery. Qualifications Education to Masters or Ph.D. level combining quantitative and/or computational skills, e.g., Computational Biology, Biostatistics/Statistical Genetics, Bioinformatics, Biomedical Informatics, Biometrics, Data Science for Health, or similar. Biological or medical knowledge, e.g., Human Disease, Genetics/Genomics, Molecular Biology, or Immunology. Comfort in a client-facing role. Proficient in R or Python. Strong understanding of the molecular nature of human disease. Expert in delivering actionable insight from transcriptomic data sets. Experience with Clinical Trial Data and/or Real World Evidence. Experience with integrative methods to model multi-modal clinical and/or omics data. Experienced in SQL. Thrive in a fast‑paced environment and willing to shift priorities seamlessly. Experience in any of the following will also be beneficial: drug R&D oncology; immunology; single cell or spatial transcriptomics; mechanistic modeling and inference; knowledge and graph‑based AI techniques. CHI: $170,000-$230,000 NYC/SF: $180,000-$250,000 The expected salary range above is applicable if the role is performed from Massachusetts and may vary for other locations (California, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. Massachusetts Applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. #J-18808-Ljbffr

A global biotechnology company seeks an experienced Associate Principal Scientist to support in vitro pharmacology projects. The role involves collaborating with pharmacologists, managing CRO relationships, and assessing external resources for early drug discovery. The ideal candidate should possess a relevant Bachelor's degree and extensive industry experience. A hybrid work model is offered. Competitive salary range from $144,800 to $227,900 annually. #J-18808-Ljbffr

Our commitment to people with neuromuscular diseases Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more ************************* and follow us on X, LinkedIn and Facebook. Role Summary: The Principal S cientist , ADME-PK in Preclinical Development (PCD) department utilize s their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance Dyne 's efforts surrounding delivery of therapeutic payloads to muscle and CNS tissues with the FORCE platform . This role is based in Waltham, MA. Primary Responsibilities Include: Design and execute internal/external preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of Dyne's drug candidates Represent PCD as the ADME-PK subject matter expert on discovery and program teams Partner with and support Research, Toxicology, Translational Biomarkers, Clinical, Regulatory, Project Management and other Dyne departments Collaborate with Clinical Pharmacology/Pharmacometrics to develop quantitative tools to translate PK/PD relationship from preclinical to clinical Author high quality Regulatory documents including INDs, CTAs, and NDA/BLA filings. Prepare strategic and science-based ADME strategies that meet regulatory requirements and program goals Facilitate strategic scientific communication via meetings, abstracts and manuscripts Education and Skill Requirements: PhD in Pharmacokinetics, Pharmacology, Pharmaceutics, Biomedical Sciences or other relevant field with >6 years (MS with >8 years, BS with >12 years) of experience in the biopharmaceutical industry, with evidence of drug development experience Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamics and bioanalytical principles F amiliarity with regulatory submission including FIH dosing strategy is highly desirable Proficient in using WinNonlin or other pharmacokinetic software Excellent communication (verbal and written) and presentation skills, as well as interpersonal skills and the ability to represent PCD in a team environment Experience with PK characterization of protein therapeutics or antibody-drug conjugates (ADCs) is desired #LI-Onsite MA Pay Range $159,000 - $195,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. #J-18808-Ljbffr

Applied Physical Sciences (APS) is looking for a highly motivated Physical Scientist to join the Concord, MA team in a part-time, on-call (PTOC) position. Successful candidates will have a PhD in theoretical physics, expertise in inverse theory or tomography, and will support the development of state-of-the-art technologies for tomographic imaging with irregular experiment apertures, with a special emphasis on exploitation of high energy X-rays. APS works on exciting, technically challenging, cutting-edge technologies that will expose candidates to a wide variety of multidisciplinary fields, providing a stimulating environment with considerable opportunity for collegial interaction. At APS you will work in a small company environment where technical excellence is rewarded and an entrepreneurial spirit is encouraged, and you will have the chance to work directly with colleagues and customers that value innovation and creativity. Responsibilities Theoretical modeling of x-ray interaction physics, development of X-ray inversion paradigms for highly challenging experiment scenarios, rigorous characterization of the fundamental information limits of X-ray imaging. Software implementation of processing and modeling techniques, numerical execution of synthetic inversion experiments, display and quantification of model uncertainty Required Attributes and Skills PhD in theoretical physics, and expertise in modeling and inversion of X-ray data Subject matter expertise in one or more of the following: advanced numerical optimization, statistical methods, experiment design optimization, GPU-based computing Extensive experience with computational methods and programming for modeling physical phenomena and processing of real data e.g., Matlab, Python, PyTorch, or Fortran Exceptional communication skills (written and oral) for technical documentation and reviews with customers Desired Attributes and Skills Professional experience of 10+ years in DoD or related industry, a strong publication history in refereed technical journals, and a track record of successful performance on research programs under DARPA, IARPA, NAVSEA or ONR sponsorship is preferred. Experience as principal investigator working on advanced R&D programs Demonstrated technical leadership in modeling and simulation Expertise in one or more of the following: mathematical physics, model-based iterative methods for x-ray tomography, Monte Carlo radiative transport methods for Bremsstrahlung modeling, advanced numerical optimization techniques involving both continuous and discrete variables, regularization methods, uncertainty quantification using the Fisher Information Matrix and the Cramer-Rao Bound, and multi-objective optimization. Experience presenting talks at technical conferences APS, a wholly owned subsidiary of the General Dynamics Corporation, offers a small company environment including competitive salary, excellent benefits, and comfortable working conditions. This is a part-time on-call position open in the Concord, MA office. Candidates must possess or be able to obtain a Top Secret DOD security clearance. Qualified applicants are invited to submit a resume and application online at **************** fax them to ************, Attn: Human Resources, or mail to the company address. Please reference the requisition number and title of the position in the subject line of your submission. Equal Opportunity Employer/M/F/Disability/Protected Vet Invitation to Self-Identify In keeping with our commitment to Equal Employment Opportunity (EEO), Applied Physical Sciences invites all applicants to self-identify pre-offer as a protected veteran and/or an individual with a disability. Invitation to Self-Identify as Protected Veteran Online Form Invitation to Voluntary Self-Identification of Disability Online Form #J-18808-Ljbffr

About the job: SciPro is partnered with a fast growing Scientific Data and AI platform startup who is searching for a Senior Applied AI/ML Engineer to join their team. They are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data across the scientific value chain and scientific vertices. They bring this AI data to life in a fast growing suite of universal lab data management solutions, scientific use cases, and AI-based scientific outcomes. Requirements: You will be a critical team member in a unique partnership to industrialize Scientific AI. As such, you will engage directly with customers onsite up to 4-5 days per week in the Boston region. Advanced degree in Biological, Data, or Computer Science Portfolio demonstrating end-to-end ownership of AI/ML products Proven track record of deploying AI models addressing real world problems Experience in biotech, biopharma, or pharma-adjacent projects Superior talent developing at least one of: ML-Reinforcement Learning, LLM/NLP, or Protein Design/Diffusion Models Responsibilities: Responsible for designing, developing, training, and validation of AI/ML products Support and advise executive leadership regarding technical and commercial feasibility Work with commercial teams to understand the impact of AI in life-sciences Collaborate with cross functional teams to build products Preferred Qualifications: Deep understanding of hurdles facing pharmaceutical drug development Demonstrated ability to make productized applications (for use by more than one group) Excellent communication skills Ability to advocate and evangelize for AI initiatives internally and externally Experience collaborating with teams on large software projects

A consulting firm specializing in healthcare seeks a Senior Consultant in Boston, MA. The role involves managing research efforts, mentoring junior consultants, and providing strategic insights to clients. Candidates should have an advanced degree or relevant experience in life sciences consulting, strong data synthesis abilities, and excellent communication skills. The position offers a competitive salary starting at $128,000 plus bonus potential, making it an attractive opportunity for professionals in the biopharmaceutical industry. #J-18808-Ljbffr

Nextcea Inc. is a pharmaceutical services company that focuses on assessing drug efficacy and safety during late-stage drug development and clinical trials. We are currently seeking full-time Analytical Chemists to join our team. Qualified candidates will actively participate in LC-MS biomarker analysis at Nextcea. Successful applicants should hold an MS or PhD in Analytical Chemistry or a related field, along with relevant laboratory experience. While experience with LC-MS is preferred, it is not mandatory. We are seeking self-motivated candidates who are excellent team players and can effectively contribute to established laboratory procedures and protocols. Candidates should be able to work independently, demonstrate flexibility, and adapt to the challenges of pharmaceutical biomarker projects. At Nextcea, we value diversity and inclusion. We offer competitive compensation and benefits, including medical, vision, dental, and 401(k) plans, to all employees, regardless of their background or identity. Applicants are required to submit their resumes online via LinkedIn.

Industry: Pharmaceuticals Title: Senior Associate Scientist Duration: 12 months contract (+Possibility of extension) Job Description: The Senior Associate Scientist, Specifications will be responsible for specification support of si RNA drug substances and drug products. This is an onsite position. Summary of Key Responsibilities: • Initiate and manage specification change controls in a GMP setting. • Expected contributions to general operations including review of data and authorship/review of technical documentation. Provide technical support as needed. • Author and review SOPs and protocols in accordance with company and regulatory guidelines. • Contribute to data review, analytical and stability sections of regulatory submissions. Assist with responses to agency requests on these sections. • Contribute to specification assessment of existing and new products. • Provie support in maintaining platform program specification documents Accountabilities • Meet goals supporting studies and defining specifications for new molecules in development. • On-time and compliant completion of review and verification of stability data to support clinical supply. • Implementation of stability and release specifications for product registration. • Adhere to core values. Knowledge/Experience/Skill: • BS or MS in Chemistry, Biochemistry or related disciplines. • Minimum of 2 years of previous experience in a cGMP analytical laboratory environment. • Preferred previous experience with stability studies designed and conducted in accordance with ICH guidelines. • Must be a team player and open to change. • Must have excellent communication and speaking skills. Can prepare presentations and present. • Preferred - experience with HPLC and physico-chemical test methods of oligonucleotides. Alternatively - experience with HPLC and physico-chemical test methods of oligosaccharides or proteins. Scope The Senior Associate Scientist Specifications will be responsible for specification support of developmental and clinical si RNA drug substances and drug products. Physical/Environmental Factors (Complete if appropriate for role) • Must be able to adhere to all laboratory safety requirements • Must be able to travel between sites Competencies • Ability to write clear technical documents and provide meaningful presentations. • Ability to work independently and in compliance with company policies and regulatory guidelines. • Excellent team skills, organization, and strong interpersonal communication skills (written and verbal)

Qualifications Bachelor's degree or higher in a relevant discipline with at least 3 years of applicable bioprocess experience. Experience with process purification of biomolecules (mAbs, vaccines, etc…) from harvest to drug substance Familiarly working in GxP cross matrix organizations Lab-scale purification process development and troubleshooting experience with standard downstream equipment (e.g. AKTAs, Repligen TFF, etc…) Direct hands on experience and knowledge of templated processes such as mAbs, pDNA, mRNA etc. Proficient expereine with data analysis tools such as Minitab, JMP, KNIME etc. Working knowledge of PAT applications development and implementation from bench scale to pilot (FlowVPE, IVI Raman etc…) Experience with HTS instrumentation for protein purification and process development. Working knowledge of GxP/ICH/Quality compliance systems of the biopharmaceutical industry Job Description We are looking for a Downstream Scientist to support our pharmaceutical client in Andover, MA. This person will lead, develop, and qualify purification techniques for biologics at both pilot and bench scale. This role involves hands-on execution of purification processes using a variety of unit operations including precipitation, depth filtration, tangential flow filtration (TFF), and chromatography. The scientist will support technology transfer, process troubleshooting, and continuous improvement initiatives. Key Responsibilities: Lead and execute purification processing using precipitation, depth filtration, TFF, and chromatography. Develop and characterize purification processes for monoclonal antibody (mAb) programs, including second-generation process development. Independently plan, design, and execute downstream experiments to support technology transfer of mAb programs. Operate and maintain downstream equipment such as AKTAs and Repligen TFF systems, and analytical tools including SoloVPE, Stunner, and Raman spectroscopy. Analyze data, prepare technical reports, and present findings to internal teams. Support manufacturing investigations and troubleshoot purification processes. Drive continuous improvement initiatives including 5S, TPM, and operational excellence. Plan and execute critical material production campaigns independently. Collaborate cross-functionally with project teams to ensure alignment and effective communication. - Familiarity with mRNA Lipid nano particle formulation and Final Drug Product (FDP) processes

Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Process R&D Scientist plays a key role in developing and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs). This position conducts small- to large-scale chemical reactions and generates high-quality data that supports project decision-making and innovation. Working under the guidance of technical leads, the role contributes to delivering projects on time, on spec, and within budget. It's an excellent opportunity to deepen expertise while supporting impactful pharmaceutical development. Core Responsibilities: Delivers experimental output with high scientific integrity, meeting targets, timelines, and quality expectations with guidance. Exhibits strong safety awareness, conducts laboratory and operational activities safely, and maintains accountability for safe behavior in the work environment. Maintains technical equipment and related services to ensure proper functionality. Acts on feedback and demonstrates a continuous commitment to learning and professional development. Leads technical and operational areas and supports troubleshooting for complex scientific issues with minimal guidance. Shares knowledge, skills, and experience effectively with internal and external stakeholders; may lead focused projects as a key contact. Keeps accurate, legible, and complete records of all experiments, observations, and equipment use. Writes high-quality reports and delivers presentations to customers and management with some guidance, aligned with project milestones. Contributes to maintaining strong customer relationships and identifies new commercial opportunities. Actively supports the technical development of the department and the broader organization. Ensures all documentation meets Veranova standards; supports audit readiness and participates in regulatory and customer audits as needed; reports near misses and safety incidents per company procedures; and ensures all work complies with applicable state and federal regulations, including GMP, DEA, and FDA requirements. Adheres to all EHS policies and procedures; demonstrates strong technical and procedural proficiency in applying EHS standards; supports EHS audit readiness and participates in audits; reports and cooperates fully in investigations of near misses and incidents; and upholds Veranova's EHS commitments by integrating ISO 14001, OHSAS 18001, and Sustainability 2025 principles into daily work. Performs additional duties within the employee's skills and abilities as reasonably assigned. Qualifications: Required PhD degree (or equivalent experience) in a chemistry related discipline. Proficiency with relevant lab and analytical techniques. Previous industry experience in relevant areas. Proficiency with relevant analytical techniques within an industry environment. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and other relevant technical software platforms. Skilled in written and spoken communication and proven ability to effectively interact with management. Demonstrates good judgment, quick decision-making skills, and the ability to work independently and in a team environment. Special Factors Must be able to stand, walk, and manually operate objects, tools, or controls; reach with hands or arms; and climb, balance, stoop, kneel, or crouch when necessary for the job activity. Must be able to lift and/or move up to 50 pounds. Specific vision abilities include near, distance, peripheral, color perception, and the ability to adjust focus. May regularly work with moving mechanical parts and may work with toxic or caustic chemicals. May work in humid areas with low or high temperatures. May be required to work with a respirator or operate with full-body Tyvek suits and supplied air or PAPR. Salary Range : $105,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .

Rangam is seeking candidates for a Direct Hire role as an Associate Scientist, Assay Development with our client, one of the world's largest pharmaceutical companies. Seeking candidates in Cambridge, MA or willing to relocate. Use Your Power for Purpose Client's purpose is to deliver breakthroughs that change patients' lives. At the core of fulfilling this purpose is Research and Development, where we translate advanced science and technologies into the therapies and vaccines that matter the most. You will be at the forefront of this mission, contributing to the discovery and development of innovative treatments that improve patients' lives. Client's BioMedicine Design (BMD) Assay Development group is seeking a highly motivated research associate to establish binding and functional assays and support hit-to-lead discovery of peptide and antibody-based therapeutics. The candidate will play a critical role in the design and execution of biochemical and of cell-based functional assays and high-throughput screening to support the BioMedicine Design portfolio. The candidate will be responsible for the development and execution of experiments using a variety of detection technologies including homogenous technology including HTRF, ELISA/DELFIA, FACS, imaging and cell-based functional assays focused on signaling, proliferation, or cytotoxicity. In addition, the candidate will analyze data, present results at internal meetings, and closely collaborate with project team members to develop strategies and identify lead molecules. We are looking for a creative, solution-oriented individual who enjoys the opportunity to explore new methods. What You Will Achieve In this role, you will: Develop assays to identify and characterize peptide, antibody and multispecific candidates to support programs across multiple therapeutic areas. Biochemical assay formats may include protein binding, competition and enzymatic cleavage assays. Cell based assays may include binding (FACS and ELISA), competition, cell signaling (NanoBiT, calcium flux, cAMP, phospho-protein HTRF/AlphaLISA, etc) and reporter gene assays using a variety of cell lines. Execute high-throughput screens using automated and semi-automated platforms and analyze results. Collaborate with project teams to establish screening strategies, interpret results, and make decisions to drive programs forward. Write protocols, maintain electronic lab notebook, and regularly review literature to maintain knowledge of scientific trends and new technologies. Here Is What You Need (Minimum Requirements): Bachelor's degree and 0-3 years of experience in molecular biology, biochemistry, cell biology or related discipline, along with a basic understanding of biologics drug discovery workflows. Demonstrated experience in assay development and troubleshooting with methods such as HTRF, ELISA/DELFIA, FACS, and cell-based functional assays focused on signaling, proliferation, or cytotoxicity. Demonstrated experience with plate-based assay formats and maintaining cell cultures is required. Track record of strong problem solving and organizational skills, attention to detail, and ability to multi-task. Strong written and oral communication skills Bonus Points If You Have (Preferred Requirements): Experience with Tecan or Beckman liquid handling platforms is preferred but not required. Experience with high content imaging and multiplex assay formats is preferred. Experience writing scripts to automate data processing or other coding experience is preferred. PHYSICAL/MENTAL REQUIREMENTS Requires work in BL2 laboratory environment with appropriate PPE Work Location Assignment: On Premise Last Day to Apply: January 22, 2026 The annual base salary for this position ranges from $60,200.00 to $97,500.00. In addition, this position is eligible for participation in client's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with client's Matching Contributions and an additional client's Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at client's Candidate Site - U.S. Benefits | (uscandidates.my**benefits.com). Compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. To find out more about Rangam, and this role, click the apply button. Satnam Singh SA Technical Recruiter | Rangam Consultants, Inc M: ************** E: *****************| W: **************

A leading cancer research institute is seeking a Higher Scientific Officer specializing in assay development and compound profiling. The successful candidate will apply screening science to advance cancer drug projects, developing plate-based assays to identify small-molecule inhibitors. This position offers a dynamic research environment supported by state-of-the-art facilities, a collaborative team, and competitive compensation. Ideal candidates will have laboratory experience and an understanding of enzymology, along with skills in automation equipment. #J-18808-Ljbffr

+++ SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker. We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing. +++ The Opportunity +++ We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today. This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels. +++ What You'll Do +++ Core Assay Development Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform. Design, execute, and interpret experiments focused on: Binding kinetics & equilibrium optimization Surface functionalization strategies Competitive assay dynamic-range shaping Calibrator and control development (matrix selection, commutability) Assay precision, stability, robustness Analytical Performance & Validation Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17). Establish and demonstrate performance for: Analytical sensitivity & functional limit (LoB/LoD/LoQ) Linearity & reportable range (including hook effects, competitive assay inflection characterization) Repeatability, reproducibility, and nested CV analysis Interference and cross-reactivity studies Matrix equivalency & recovery studies Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks). Cross-Functional Integration Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance. Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing. Documentation & Execution Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations. Present results across the company to inform design decisions and product milestones. +++ What We're Looking For +++ Technical Background PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields. Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus. Demonstrated ability to independently solve complex analytical and biochemical problems. Hands-on experience with complex analytical workflows, assay automation, and instrumentation. Strong understanding of calibration design, commutability, and control strategies. Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks. Regulatory & Platform Experience (Bonus) Experience with IVD development, ISO 13485, or 21 CFR 820. Experience with POC or novel-platform assay development. Knowledge of label-free sensors, waveguides, or photonic resonance systems. Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation. Personal Traits Strong scientific intuition paired with rigorous data discipline. Thrives in a fast-paced, milestone-driven startup environment. Creative problem solver willing to challenge established assay paradigms. High integrity, willingness to own outcomes, and a collaborative mindset. +++ Why This Role Is Unique +++ Most assay developers spend their careers optimizing assays on platforms that already exist. At SiPhox, you will: Build the first generation of photonic immunoassays deployed in consumer health. Design assays whose constraints are shaped by semiconductor physics as much as biochemistry. Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins. See your work ship in a product used at home by real people, not just research labs. If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.

Title: Senior Research Associate - Cell & Gene Therapy (Analytical Development) Employment Type: Contract (12 months) Status: Accepting Candidates About the Role Join a fast-paced Cell & Gene Therapy analytical development team supporting preclinical and clinical programs. This role is hands-on and bench-focused, contributing directly to assay execution, data generation, and process development. Key Responsibilities Perform routine analytical testing to support process development, characterization, and release assays Execute cell-based and plate-based assays including potency, ELISA, MSD, and molecular assays Conduct Flow Cytometry, qPCR/PCR, and mammalian cell culture experiments Document experiments in Benchling ELN and maintain clear, compliant records Support sample handling, inventory tracking, and cross-functional collaboration Qualifications BS with 5+ years or MS with 3+ years of industry experience (PhD not required) Background in Cell & Gene Therapy, biotech, or biologics Strong hands-on experience running bench experiments independently Proficiency with Flow Cytometry, plate reader assays, and cell culture Experience in Analytical Development within a regulated lab environment Compensation (MA Pay Transparency): Estimated hourly range: $40-$48/hr (W-2) Final rate within this range will be based on skills, experience, and interview results.

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

A biotechnology company in Waltham, MA is seeking a Principal Scientist in ADME-PK to enhance drug delivery to muscle and CNS tissues. The successful candidate will design preclinical studies, author regulatory documents, and collaborate across various teams. Candidates should possess a PhD in a relevant field and over 6 years of industry experience, with expertise in pharmacokinetics and drug metabolism. This role offers a competitive salary in the range of $159,000 to $195,000 USD depending on experience. #J-18808-Ljbffr

A leading healthcare technology firm in Boston seeks an Associate Principal Scientist to advance drug R&D through computational research. The ideal candidate will leverage the Tempus platform to analyze diverse datasets, ensuring actionable insights for clients. This role requires a Masters or Ph.D. in areas like Bioinformatics or Data Science, proficiency in R or Python, and comfort in client interactions. A competitive salary range of $170,000-$230,000 reflects the expertise required for this role, alongside comprehensive benefits. #J-18808-Ljbffr

Discover Veranova: At Veranova, we believe people are our most important asset, and we are dedicated to building the most talented workforce in our industry. Our commitment to uncompromising focus on quality, compliance, safety, and excellence in delivery shapes everything we do. We are not just looking for skills; we are seeking innovative individuals who have a mindset open to learning and growth, and a desire to make a difference. Veranova is a global leader in the development and manufacturing of complex active pharmaceutical ingredients (APIs) for pharma and biotech customers. With deep technical expertise and impressive flexibility, we develop solutions and processes that support and accelerate innovation. Join us on our mission to enable current and next-generation therapeutics to improve and save the lives of patients. Role Overview: The Scientist role within the Chemical Development group will focus on the synthesis, process development, and analytical strategy for protected phosphoramidite precursors used in therapeutic oligonucleotide API manufacturing. This position is key to building Veranova's commercial capability in producing high-quality oligonucleotide building blocks. The ideal candidate will have strong expertise in phosphoramidite chemistry, including impurity profiling and customer-specific requirements. This role will also collaborate closely with the Analytical Team to establish robust characterization and control strategies that ensure exceptional product quality. Core Responsibilities: Develop and optimize synthetic routes for protected Phosphoramidite subunits used in therapeutic oligonucleotide API synthesis. Identify and mitigate side reactions commonly associated with Phosphoramidite chemistry. Define and implement specifications aligned with customer expectations for commercial-grade oligonucleotide precursors. Provide expert guidance to the Analytical Team on the selection and application of appropriate analytical methods for product and impurity characterization, based on prior experience and industry standards. Collaborate with cross-functional teams including Analytical Development, Quality, and Manufacturing to ensure successful scale-up and tech transfer. Prepare technical documentation including batch records, specifications, and development reports in accordance with SOPs and cGMP guidelines. Present scientific findings and project updates to internal stakeholders and external customers. Support the establishment of quality and regulatory standards for commercial production of oligonucleotide precursors. Contribute to project planning, budgeting, and timeline management for precursor development programs. Other duties as assigned . Qualifications: Required BS in Organic Chemistry or equivalent with 3-5 years related experience in a pharmaceutical industry, or MS in Organic Chemistry or equivalent with 0-2 years related experience in the pharmaceutical industry. Ability to read, analyze, and interpret English-language chemical periodicals, scientific journals, and regulatory documents. Experience with organic synthesis and process development Experience with common analytical techniques such as HPLC, GC, NMR, UV, and LC-MS. Experience in establishing integrated plans with defined resources and tasks. Ability to write clear and concise technical reports. Good understanding of Microsoft Office and statistical software. Demonstrate ability to exercise good judgment and make decisions quickly. Good written and verbal communication skills. Ability to work independently and in a team environment. Salary Range : $110,000 - $120,000 annual base salary Our Commitment: Health & Wellness: Comprehensive health & wellness benefits. Access to mental health resources and wellness programs. Generous PTO and holiday pay policies. Financial Wellness: Veranova is committed to fair and transparent compensation practices. This includes a competitive base salary, eligibility for performance-based bonuses, and an attractive 401(k) Plan with company match. Salary ranges reflect the scope and expectations of the role, and are based on market data, internal equity, and role-specific factors. Final compensation may vary depending on experience, skills, education, and business needs. Professional Development: Opportunities for continuous learning through LinkedIn Learning, workshops, conferences, and mentorship. Tuition Assistance for Undergraduate and Graduate degree programs. Inclusive Culture: At Veranova, an inclusive culture is integral to our values. We welcome people with diverse experiences and perspectives who share our mission to improve and save lives. Even if you don't meet every qualification, we encourage you to apply. Veterans, first responders, and those transitioning from military to civilian life bring valuable skills that strengthen our team. Additional Information: Applicants for this role must be authorized to work in the United States without further employer sponsorship. Agency and Search Firm Representatives: Veranova does not accept unsolicited resumes from agencies and/or search firms for this job posting. All your information will be kept confidential according to EEO guidelines. Veranova is an Equal Opportunity Employer. It is the policy of Veranova to provide equal employment access and opportunity to all persons regardless of age, race, color, national origin, religion, sex, sexual orientation, gender identity and/or expression, physical or mental disability, genetic information, citizenship, marital status, veteran status, or any other characteristic protected by federal, state, or local law. All applications are carefully considered, and your details will be stored on our secure Application Management System. This is used throughout Veranova for the selection of suitable candidates for our vacancies as they arise. Veranova respects your privacy and is committed to protecting your personal information. For more information about how your personal data is used please view our privacy notice .