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  • Clinical Scientist Data Reviewer

    Advanced Clinical 3.8company rating

    Senior principal scientist job in Jersey City, NJ

    6 month contract w/ renewal 3 days onsite in Jersey City, NJ We are seeking a Clinical Scientist Data Reviewer that will support the scientific planning efforts and collaborate with Clinical Research, Pharmacovigilance and Clinical Operations in the execution of one or more clinical trials or significant aspects thereof. In this position, you will have the opportunity to demonstrate technical skills and scientific acumen as part of a cross-functional clinical development team. You will be a key contributor and supporter in the clinical science activities of evidence generation for regulatory approval and/or engagement with physicians, including protocol development, study implementation, data analysis and reporting of results. This role will be focused on the detailed and critical safety data review efforts from study start-up through final CSR. The Clinical Scientist Data Reviewer is a crucial role in analyzing and interpreting clinical trial data to ensure accuracy, integrity, and compliance with regulatory requirements. There is additional room for growth and leadership opportunities in this role. Responsible for supporting specific aspects of clinical/scientific execution of clinical protocol(s). This may include: Serving as a supportive clinical scientist data reviewer focused on safety, efficacy and critical data deliveries as part of the clinical trial team Supporting the clinical study team as part of the clinical sciences functional line which is closely aligned with the medical monitoring team in review and interpretation of clinical data/medical protocol deviations in collaboration with Clinical Research and Pharmacovigilance (as well as other functional areas in this matrix environment) Collaborating cross-functionally in the development of Protocol and related study materials (e.g., ICF documents / amendments); partnering with Clinical Operations on critical and key study deliverables Ensure CRF design supports data collection in alignment with the Protocol in collaboration with Clinical Data Management/Programming Collaborating cross-functionally to review clinical data to ensure quality, completeness, and integrity of trial conduct Potential to provide tactical/scientific mentorship to other clinical scientists and move into Clinical Scientist lead role as well as focus on scientific growth and development Responsible for assisting with the generation, analysis, and presentation of clinical data, including manuscripts, abstracts, and oral presentations (including authoring documents and slide preparation as appropriate) Apply proficient analytical knowledge and skills to understand how program objectives and design impact data analysis; identifies risks and designs mitigation strategies Promotes consistent first line medical/clinical data review techniques and conventions across studies/programs Qualifications 6+ years of experience with a Post Graduate Degree or 8+ years of experience with a Bachelor's degree in a relevant scientific discipline. Experience in clinical drug development experience, or a PhD, Pharm D, or RN degree is preferred. Experience within oncology preferred Solid knowledge of clinical research regulatory requirements (e.g., GCP and ICH) Ability to manage multiple competing priorities with good planning, time management and prioritization skills Strong analytical skills with the ability to interpret clinical trial data and synthesize conclusions Proficient scientific expertise to propose, design, and execute clinical research and development studies, and authors documents related to clinical trials, such as medical monitoring plan, SAPs, informed consent and clinical components of the Clinical Study Reports Interact with key stakeholders across Clinical Development functional areas Role requires proactive approach, strategic thinking and leadership in driving toward clinical study goals Influence opinions and decisions of internal and external customers / vendors, across functional areas Problem solving, prioritization, conflict resolution and critical thinking skills Strong communication, technical writing, and presentation skills experience
    $111k-154k yearly est. 4d ago
  • Oncology Late Stage Clinical Scientist (Senior Manager, Non MD)

    Pfizer 4.5company rating

    Senior principal scientist job in New York, NY

    You will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Late-Stage Oncology portfolio. KEY RESPONSIBILITIES Clinical development expert for assigned studies maintaining current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Effectively partner with other clinical and medical colleagues, clinical operations and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. Responsible for scientific oversight, data integrity and quality of the clinical trial(s). Represent the study team in governance meetings and submissions, partners with/supports the Development lead/Medical Director regarding study and disease area strategy. Author protocols, study level informed consent documents, and contributes to authoring of IBs, site training materials, clinical study reports, regulatory responses, and other clinical and regulatory documents; supports preparations for Health Authority meetings, participates as appropriate . Set the clinical data review strategy and leads the team in the collection of quality data and review of emerging clinical data and trends; reviews and queries data; presents and discusses relevant data to appropriate teams , governance bodies, and other internal and external stakeholders. In close partnership with medically qualified colleague/s , analyze the emerging safety profile of the drug, keeping the clinical and safety colleagues informed of changes in the safety profile as they occur in the assigned trial(s). Follow relevant SOPs and regulations, has an excellent understanding of and complies with applicable trainings , seeks opportunities to further improve quality and efficiency of clinical procedures; leads or actively participates in portfolio- and enterprise level workgroups aimed at optimizing PFE clinical development procedures; may be a subject matter expert or business process owner for a relevant SOP or procedure. MINIMUM QUALIFICATIONS PhD/Pharm D in a relevant Science discipline and minimum of 2 years Clinical Research experience in industry/CRO, OR MS in a relevant Science discipline and minimum of 5 years of Clinical Research experience in industry/CRO OR BA/BS in a relevant Science discipline and minimum of 7 years Clinical Research experience in a similar role in industry/CRO Clinical Research experience in the phase 3/pivotal space in Oncology, ideally on the side of the sponsor and with a track record of successful regulatory submission, inspection, and regulatory approval. Excellent knowledge of clinical procedures, ICH guidelines, GCP and familiarity with FDA, EMA, and global regulations. Extensive understanding of related disciplines, e.g., Clinical Operations, Safety, Biostatistics, Regulatory, Study Management, Pre-clinical, Pharmacology, Quality Assurance. Experience working on large data sets. Proficiency with Microsoft Office and relevant scientific software Effective communication, presentation, and organizational skills to ensure coordinated and timely delivery. Experience leveraging a variety of communication tools and techniques to communicate results Experience solving problems collaboratively and handling conflict constructively. Track record of scientific productivity as evidenced by publications, posters, abstracts and/or presentations. Experience working proactively and independently, organizing tasks, time and priorities of self and others. Experience building partnerships across the company to achieve the needs of the program. PREFERRED QUALIFICATIONS Experience in Hematology Oncology COMPETENCIES FOR SUCCESS Demonstrates passion for helping patients with cancer and for the science of oncology. Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned. Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities. Promotes team health and exemplifies Pfizer's leadership behaviors and actionable attitudes. Leverages knowledge and support from others related to overall objectives , strategy, critical issues, and policies. Demonstrates foresight and judgment to make complex decisions Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes. Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies . both as a leader and a key contributor Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Work Location Assignment: This is a Hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. The annual base salary for this position ranges from $135,100.00 to $225,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. Medical
    $135.1k-225.1k yearly 18h ago
  • Senior Scientist of Research and Molecular Assay Development

    Sonic Healthcare USA 4.4company rating

    Senior principal scientist job in Rye Brook, NY

    We're not just a workplace - we're a Great Place to Work certified employer! Proudly certified as a Great Place to Work, we are dedicated to creating a supportive and inclusive environment. At Sonic Healthcare USA, we emphasize teamwork and innovation. Check out our job openings and advance your career with a company that values its team members! Location: Rye Brook, NY Days: Monday - Friday Salary range: $150K - $195K Hours: 8:00 AM - 5:00 PM Full-time: Benefit Eligible In this role, you will: Collaborate with senior leadership to align research and clinical validation priorities with organizational goals. Supervise and mentor a team of Molecular Technologists working under their supervision, fostering a culture of scientific excellence and continuous improvement. Oversee daily molecular R&D testing operations, ensuring accuracy, efficiency, and compliance with any regulatory agency at any level. Lead the design, optimization, and validation of high-throughput molecular assays for clinical and pharma applications. Conduct comprehensive validation studies, including precision, accuracy, sensitivity, and specificity assessments. Review the critical steps in developing new assays or technologies. Provide scientific and technical guidance for assay troubleshooting. Maintain robust quality assurance and quality control programs; implement corrective actions as needed. Develop, review, and update SOPs to ensure compliance with regulatory and accreditation standards. Collaborate with the QA Manager to prepare for inspections and audits; provide detailed reports and documentation. Identify emerging technologies and methodologies to enhance molecular testing capabilities. Collaborate with cross-functional teams to support research initiatives and pharma partnerships. Contribute to strategic planning for laboratory growth and integration of novel molecular platforms. Perform other job-related duties as assigned. Ensure adherence to CAP/CLIA/NYSDOH standards, other regulatory agencies, and internal SOPs. Manage and coordinate the procurement of laboratory supplies and equipment, as well as for special projects. Ensure all instrument maintenance is performed and documented; administer all established quality control procedures; and troubleshoot instruments effectively when appropriate. Maintain medical laboratory supplies inventory, determine inventory level, and anticipate needed supplies. We'll give you: Appreciation for your work A feeling of satisfaction that you've helped people Opportunity to grow in your profession Free lab services for you and your dependents Work-life balance, including Paid Time Off and Paid Holidays Competitive benefits including medical, dental, and vision insurance Help saving for retirement, with a 401(k) plus a company match A sense of belonging - we're a community! Scheduled Weekly Hours: 40 Work Shift: Job Category: Laboratory Operations Company: Sonic Healthcare USA, Inc Sonic Healthcare USA is an equal opportunity employer that celebrates diversity and is committed to an inclusive workplace for all employees. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, age, national origin, disability, genetics, veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
    $150k-195k yearly Auto-Apply 3d ago
  • Staff Scientist, Microbiology

    BD (Becton, Dickinson and Company

    Senior principal scientist job in Franklin Lakes, NJ

    We are **the makers of possible** BD is one of the largest global medical technology companies in the world. Advancing the world of health is our Purpose, and it's no small feat. It takes the imagination and passion of all of us-from design and engineering to the manufacturing and marketing of our billions of MedTech products per year-to look at the impossible and find transformative solutions that turn dreams into possibilities. We believe that the human element, across our global teams, is what allows us to continually evolve. Join us and discover an environment in which you'll be supported to learn, grow and become your best self. Become a **maker of possible** with us. The R&D team is seeking an exceptionally talented and passionate individual to help us identify and implement innovative solutions to address current and future health care needs. Within BD Medication Delivery Solutions (MDS) Research & Development, the Staff Scientist, Microbiology will be part of the Materials Science team in Franklin Lakes NJ, reporting to the Associate Director, Materials Science. Our R&D Engineers and Scientists are responsible for developing and implementing new product materials and designs, product improvements, and critical component changes for disposable and durable medical devices. The preferred candidate will have strong technical skills, excellent written and oral skills, and leadership abilities. This candidate should possess a strong capability to interpret and ensure compliance with all local, state, federal and BD safety regulations, quality policies, best practices, and procedures through appropriate communication. The Staff Scientist, Microbiology plays a critical role in ensuring the microbiological integrity of products and processes throughout the development lifecycle. This position provides technical leadership in microbiology-related risk assessments, method development, and validation activities, supporting compliance with global regulatory requirements and internal quality standards. The role requires strong collaboration with cross-functional teams, including Platform Product R&D, Regulatory Affairs, and Manufacturing, to deliver safe, effective, and innovative medical devices. **Key Responsibilities:** + **Microbiological Risk Management:** + Lead microbiological risk assessments for new product development and sustaining projects. + Define and implement contamination control strategies aligned with ISO 11737, ISO 11135, and related standards. + Develop solutions to both unique and routine technical problems related to the assigned projects. + **Method Development & Validation:** + Provide technical leadership for key aspects of development projects requiring the design and performing of microbiology experiments in the laboratory that includes culture of pathogenic bacteria and fungi, and handling of blood and blood products. + Develop and validate microbiological test methods (bioburden, sterility, endotoxin, environmental monitoring). + Ensure robustness and compliance of methods with USP, EP, and ISO requirements. + **Sterilization & Cleanliness Support:** + Partner with sterilization engineers to establish and maintain validated sterilization processes. + Support packaging integrity and EO residual testing strategies. + **Regulatory & Quality Compliance:** + Author and review microbiology-related sections of regulatory submissions (510(k), CE marking, etc.). + Ensure adherence to GMP, ISO 13485, and FDA QSR requirements. + **Cross-Functional Collaboration:** + Provides experimental data and technical input to other scientists within R&D and provides support to other functional groups in pursuit of project objectives. + Serve as the microbiology SME in design reviews, hazard analyses, and CAPA investigations. + Provide guidance to project teams on microbiological considerations impacting design and manufacturing. + **Continuous Improvement:** + Identify opportunities to optimize microbiological testing efficiency and reliability. + Mentor junior associates and contribute to knowledge-sharing initiatives. + **Leadership** + Lead cross-functional technical governance for microbiology-related risk management and compliance, ensuring alignment with corporate and regulatory expectations. + Mentor and coach senior scientists and engineers, building organizational capability in microbiology evaluations. + Provide technical leadership for critical business decisions, including supplier qualification, material selection, and new technology adoption. + Engage with regulatory agencies and notified bodies as BD's microbiology subject matter expert during audits and inspections + Serve as global microbiology thought leader, representing BD in external technical forums, standards committees, and industry working groups. **Qualifications:** + Minimum bachelor's degree in microbiology or related field required, advanced degree preferred + Minimum 5 years of experience in microbiology within medical devices, pharmaceuticals, or related regulated industry. + Proven expertise in sterilization validation, bioburden control, and microbiological method development. + Research experience in microbiology, biochemistry or a related field that includes culturing and manipulation of microorganisms. + Experience in laboratory techniques in microbiology with demonstrated skills in adapting procedures to meet specific objectives and solve problems. + Strong knowledge of ISO 11737, ISO 11135, USP , , and related standards. + Understand and follow biosafety practices and use aseptic technique when working in microbiology labs. + Comprehensive knowledge of the medical device product development process under a quality management system in a regulated environment (ISO 13485, FDA cGMP/cGLP, etc) + Excellent analytical, problem-solving, and technical writing skills. + Ability to manage multiple priorities in a fast-paced environment. + Effective communicator and collaborator across functions and levels. At BD, we prioritize on-site collaboration because we believe it fosters creativity, innovation, and effective problem-solving, which are essential in the fast-paced healthcare industry. For most roles, we require a minimum of 4 days of in-office presence per week to maintain our culture of excellence and ensure smooth operations, while also recognizing the importance of flexibility and work-life balance. Remote or field-based positions will have different workplace arrangements which will be indicated in the job posting. For certain roles at BD, employment is contingent upon the Company's receipt of sufficient proof that you are fully vaccinated against COVID-19. In some locations, testing for COVID-19 may be available and/or required. Consistent with BD's Workplace Accommodations Policy, requests for accommodation will be considered pursuant to applicable law. At BD, we are committed to supporting our associates' well-being, development, and success through a performance-based culture. For this position, BD offers a competitive compensation package along with the following benefits specific to this role: + Annual Bonus Health and Well-being Benefits + Medical coverage + Health Savings Accounts + Flexible Spending Accounts + Dental coverage + Vision coverage + Hospital Care Insurance + Critical Illness Insurance + Accidental Injury Insurance + Life and AD&D insurance + Short-term disability coverage + Long-term disability insurance + Long-term care with life insurance Other Well-being Resources + Anxiety management program + Wellness incentives + Sleep improvement program + Diabetes management program + Virtual physical therapy + Emotional/mental health support programs + Weight management programs + Gastrointestinal health program + Substance use management program + Musculoskeletal surgery, cancer treatment, and bariatric surgery benefit Retirement and Financial Well-being + BD 401(k) Plan + BD Deferred Compensation and Restoration Plan + 529 College Savings Plan + Financial counseling + Baxter Credit Union (BCU) + Daily Pay + College financial aid and application guidance Life Balance Programs + Paid time off (PTO), including all required State leaves + Educational assistance/tuition reimbursement + MetLife Legal Plan + Group auto and home insurance + Pet insurance + Commuter benefits + Discounts on products and services + Academic Achievement Scholarship + Service Recognition Awards + Employer matching donation + Workplace accommodations Other Life Balance Programs + Adoptionassistance + Backup day care and eldercare + Support for neurodivergent adults, children, and caregivers + Caregivingassistancefor elderly and special needs individuals + Employee Assistance Program (EAP) + Paid Parental Leave + Support for fertility, birthing, postpartum, and age-related hormonal changes Leave Programs + Bereavement leaves + Military leave + Personal leave + Family and Medical Leave (FML) + Jury and Witness Duty Leave **Why Join Us?** A career at BD means being part of a team that values your opinions and contributions and that encourages you to bring your authentic self to work. It's also a place where we help each other be great, we do what's right, we hold each other accountable, and learn and improve every day. To find purpose in the possibilities, we need people who can see the bigger picture, who understand the human story that underpins everything we do. We welcome people with the imagination and drive to help us reinvent the future of health. At BD, you'll discover a culture in which you can learn, grow, and thrive. And find satisfaction in doing your part to make the world a better place. To learn more about BD visit ********************** Becton, Dickinson, and Company is an Equal Opportunity Employer. We evaluate applicants without regard to race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status, and other legally-protected characteristics. Required Skills Optional Skills . **Primary Work Location** USA NJ - Franklin Lakes **Additional Locations** **Work Shift** At BD, we are strongly committed to investing in our associates-their well-being and development, and in providing rewards and recognition opportunities that promote a performance-based culture. We demonstrate this commitment by offering a valuable, competitive package of compensation and benefits programs which you can learn more about on our Careers Site under Our Commitment to You (********************************************* . Salary or hourly rate ranges have been implemented to reward associates fairly and competitively, as well as to support recognition of associates' progress, ranging from entry level to experts in their field, and talent mobility. There are many factors, such as location, that contribute to the range displayed. The salary or hourly rate offered to a successful candidate is based on experience, education, skills, and any step rate pay system of the actual work location, as applicable to the role or position. Salary or hourly pay ranges may vary for Field-based and Remote roles. **Salary Range Information** $130,400.00 - $215,200.00 USD Annual Becton, Dickinson and Company is an Equal Opportunity/Affirmative Action Employer. We do not unlawfully discriminate on the basis of race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status, or any other protected status.
    $130.4k-215.2k yearly 3d ago
  • Research Scientist

    ATG 4.2company rating

    Senior principal scientist job in New York, NY

    About us ATG (Autonomous Technologies Group) is an AI lab deploying frontier reasoning systems within financial markets. Founders: Early GPU cloud (9 figure exit). Investors: Garry Tan / YC + Founder of one of the most successful quant funds, BoxGroup (Plaid, Ramp, Stripe), top-tier angels. About the Role You'll drive original research at the boundaries of AI, working on new models, algorithms, and architectures for reasoning in complex environments. Your work will shape the scientific agenda of the lab and inform everything we build. You'll have autonomy to pursue fundamental research and see your ideas deployed in real-world settings. Responsibilities Formulate and explore open questions in deep learning, reinforcement learning, and agent-based AI. Develop novel architectures, algorithms, and theoretical insights. Collaborate with engineers to implement, experiment, and iterate rapidly. Publish, present, and contribute to the broader research community. Mentor and support the next generation of technical talent. Requirements Demonstrated track record of impactful AI/ML research (e.g., papers, open-source, or novel deployments). Deep expertise in at least one of: LLMs, RL, agent-based systems, generative modeling, theory of intelligence. Strong mathematical background (probability, optimization, statistics). Proficiency in Python and modern ML frameworks (e.g., PyTorch, JAX). Ability to turn theory into robust, practical code. Up-to-date on the latest research in LLMs from reading papers, articles, or re-implementing breakthroughs. Expertise in leveraging the latest AI tools (Cursor, Claude Code, Codex, etc) to increase productivity & code output while maintaining high code quality, maintainability, and structure. Why Join ATG We're building a small, elite team. If you're excited by AI, markets, and building from first principles, we'd love to meet you. Work on AI with a massive market opportunity Early team of repeat founders backed by top investors High agency, talent dense, zero bureaucracy
    $67k-100k yearly est. Auto-Apply 60d+ ago
  • Scientist, Discovery Science

    Volastra

    Senior principal scientist job in New York, NY

    COMPANY Volastra Therapeutics, Inc. is a clinical-stage oncology biotech company based in New York City, pioneering novel approaches to treating cancer by targeting chromosomal instability (CIN), a unique vulnerability in cancer. Since its founding in 2019, Volastra has grown to support ongoing discovery efforts and a growing clinical organization. Our lead pipeline programs focus on two distinct inhibitors of KIF18A, a novel therapeutic target. VLS-1488, internally discovered, entered clinical trials in Q4 2023 for the treatment of advanced cancers. Sovilnesib, in-licensed from Amgen in 2023, re-entered the clinic in Q2 2024. Both assets have been granted Fast-Track Designation by the FDA. Volastra is also developing new techniques to understand the biology of chromosomal instability and leveraging these insights to drive forward a preclinical pipeline of therapies against innovative targets. Volastra is backed by top US and European venture firms such as Arch, Polaris, Vida, Droia, Catalio, and B Capital, alongside strategic investment from Eli Lilly. In addition to venture funding, Volastra has established partnerships with oncology leaders. Our senior leadership team is highly experienced, supported by a world-class advisory board. We are headquartered in West Harlem, New York City, within easy reach of Columbia, Cornell, Memorial Sloan Kettering, and surrounding areas. Please visit ****************** for more information. JOB DESCRIPTION: The role of Scientist of Discovery Science will report to the Senior Scientist/Senior Lab Manager in close collaboration with the Chief Scientific Officer and the rest of the Discovery Team, and work towards the successful execution of preclinical development programs. As a scientist, you will play a central role in turning foundational CIN biology into new medicines. You will design, execute, and interpret rigorous experiments that validate targets, elucidate mechanism of action, and accelerate progression from hit/lead to in vivo proof‑of‑concept. This is a bench‑forward position for a creative, self‑directed experimentalist who thrives in a fast‑moving biotech setting and loves collaborating across chemistry, biochemistry, DMPK, in vivo pharmacology, and computational biology. Volastra is a fast-paced biotech company of passionate employees, and there is ample opportunity for the ideal candidate to grow and develop with the organization. Individuals will have, from time to time, the opportunity to gain experience with projects outside their direct scope of work. Job is based in NYC and requires a minimum of 80% in office time. RESPONSIBILITIES: * Participate in key discovery workstreams from target validation through early pharmacology; design clear, decision‑driving experimental plans and timelines. * Interrogate mechanism using genetic perturbation (e.g. CRISPR/Cas9, RNAi), rescue, pathway mapping, and combination studies aligned with CIN biology. * Develop and optimize cellular assays to quantify phenotype and mechanism. * Build translationally relevant target‑engagement and PD assays to enable SAR and inform dose/PK-PD modeling for in vivo studies. * Track record of successfully managing external projects with CRO's from scoping to final data delivery * Work effectively with colleagues across the team to participate in adjacent discovery-related efforts * Provide clear updates to Discovery, Preclinical, and Leadership; write technical reports, support patent filings, and prepare data packages for milestones. REQUIREMENTS: * PhD in Molecular/Cell Biology, Biochemistry, Cancer Biology, Pharmacology or related field (or MS/BS with commensurate depth of industry experience). * 5+ years of hands-on lab experience with a range of relevant research techniques including cell-based assays and molecular biology. In vivo mouse experience is strongly preferred * Understanding of the drug development process from target identification to marketing authorization is strongly encouraged * Excellent communication, organizational, and problem-solving skills * Ability to collaborate well with team members PREFERRED EXPERIENCE: * Direct experience in CIN‑relevant biology (mitosis, microtubules/kinetochore function, replication stress, DNA‑damage response) or image‑based phenotyping * In vivo oncology familiarity (xenograft/PDX syngeneic models), PK/PD thinking, and translational biomarker awareness for discovery‑to‑development continuity. Salary Range: Approximately $130,000 - $150,000 which may vary depending on qualifications, experience, and ultimate leveling. Leveling outside of that stated may be considered for exceptional candidates on a case-by-case basis.
    $130k-150k yearly Auto-Apply 29d ago
  • Scientist, Molecular Profiling

    Immunai 4.0company rating

    Senior principal scientist job in New York, NY

    Immunai is an engineering-first platform company aiming to improve therapeutic decision-making throughout the drug discovery and development process. We are mapping the immune system at unprecedented scale and granularity and applying machine learning to this massive clinico-immune database, in order to generate novel insights into disease pathology for our partners - pharma companies and research institutes. We provide a comprehensive, end-to-end solution - from data generation and curation to therapeutics development, that continuously supports and validates the capabilities of our platform. As drug development is becoming increasingly inefficient, our ultimate goal is to help bring breakthrough medicines to patients as quickly and successfully as possible. Immunai is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. About the role: This position offers an opportunity to work in a highly-collaborative environment with world-leading scientists developing and applying state-of-the art profiling technologies to a diverse set of projects at the intersection of the immune system and disease. The successful candidate will work in a fast-paced team and will interface closely with a multidisciplinary team of immunology, molecular biology, and bioinformatics scientists. Specifically, they will contribute to the Molecular Profiling team performing advanced molecular analyses on a diverse set of clinical and experimental samples. The successful candidate will be an excellent team player, agile in thought, energetic, and willing to learn new methods and skills. Location: New York City (On-site role) What will you do? * Augment efforts of teams using a wide range of techniques including, but not limited to immune cell isolation and processing from human specimens, cell cultures and in vitro model systems * Domain expert with single cell genomics methods, and proven experience of innovation in this field (sample optimization, protocol development). * Operation, calibration and maintenance of flow cytometers, cell sorters and related equipment and associated computational hardware * Maintenance of a complete, accurate, and timely electronic record of all experiments using an informatics management system. * Active participation in cross-functional team meetings and effective communication with other members of the lab, computational biology, and software team * Expected to deliver impactful presentations to other colleagues including senior leadership Requirements Required qualifications: * 4-6 years of experience in Molecular Biology or Immunology; * MS with 2-4 years relevant experience, PhD with 1+ years of post-PhD experience is preferred. * Experience with protocols for sample and library preparation for single cell multiomics and familiarity with NGS processes. Additionally, familiarity with high-throughput, automated single cell profiling workflows is preferred. * Experience working with tissue samples, including single cell dissociation. * Experience with sectioning, staining (immunohistochemistry, fluorescence microscopy, in situ hybridization), imaging and basic image analysis is a distinct advantage * Familiarity with high throughput lab data management (e.g. Benchling) * Strong analytical skills, problem solving ability, and innovation aptitude required * Must be willing to discover and learn new software and technology applications quickly * Must have strong attention to detail and an ability to multitask * Ability to collaborate closely with interdisciplinary individuals from a broad range of backgrounds * Ability to work independently with minimal supervision * Ability to work successfully in a fast-paced environment * Excellent interpersonal skills and ability to effectively work as part of a team are essential * Excellent organization and time management skills Desired personal traits: * You want to make an impact on humankind * You prioritize "We" over "I" * You enjoy getting things done and striving for excellence * You collaborate effectively with people of diverse backgrounds and cultures * You have a growth mindset * You are candid, authentic, and transparent Compensation: This position offers a salary typically between $105,000 - $140,000. There is an opportunity to consider higher compensation above this range based on business need, candidate experience, and or skills. * Please note that when you apply for a position at Immunai, your application will be processed via our recruitment platform SparkHire. You can read more about how we process personal data here: ***************************************
    $105k-140k yearly 12d ago
  • Associate Scientist, Chemical & Process Sciences - Port Newark, NJ

    Dsm-Firmenich

    Senior principal scientist job in Newark, NJ

    Associate Scientist - Chemical & Process Sciences Join us as an Associate Scientist, Chemical & Process Sciences, where you'll independently conduct and analyze lab experiments, collaborate on process scale-up, and drive innovation in a safety-focused, growth-oriented environment. Ideal for hands-on chemists passionate about process improvement and teamwork in a sustainable, leading-edge company. **Your Key Responsibilities:** + Plan and design experiments in alignment with supervisor guidance. + Set up and operate laboratory equipment-including glassware and high-pressure reactors-largely independently to conduct experimental procedures. + Analyze samples using gas chromatography (GC) and wet chemistry analytical techniques. + Compile, interpret, and present experimental data to the supervisor. + Interact with production personnel (operators, shift leaders) as needed during process industrialization and troubleshooting. + Maintain overall laboratory housekeeping, ensuring a safe and organized work environment. + Manage timely ordering and proper handling of laboratory supplies. **We Bring:** + A rich history and a promising future of bold scientific innovation and passionate creation with our customers; + A space to grow by encouraging and supporting curiosity and an open mindset; + A culture that prioritizes safety and well-being, both physically and mentally; + The opportunity to work for a company where sustainability is much more than a claim and is core to our strategy and purpose; + An eagerness to be one team and learn from each other to bring progress to life and create a better future; + We offer competitive pay, career growth opportunities, and outstanding benefit programs. **You Bring:** + M.S. in Organic Chemistry or a closely related field with at least 1 year of industrial experience, B.S. degree in Chemistry with at least 3-5 years of industrial experience will be considered. + Exceptionally qualified new graduates will also be considered. + Hands-on experience in synthetic chemistry and separation operations, such as fractional distillation, is required. + Curious and open-minded, with excellent communication skills and a team-player spirit + Ability to work largely independently, with strong organizational skills, the ability to set priorities, and a results-oriented approach + Passion for process improvement and precision + Background in industrially relevant organic chemistry + Good written and oral presentation skills + Strong interpersonal skills and a collaborative attitude The salary or hourly wage scale provided reflects the pay range dsm-firmenich expects to pay the successful candidate for the position. Individual pay offered will be based on the applicant's job-related skills, experience, relevant education, or training, and primary work location. This position is also eligible for bonuses and benefits, which are not included in the pay scale provided. Salary $97,000-$139K. **About dsm-firmenich** At dsm-firmenich, we don't just meet expectations - we go beyond them. Join our global team powered by science, creativity, and a shared purpose: to bring progress to life. From elevating health to making fortified food and sustainable skincare, the impact of your work here will be felt by millions - every single day. Whether it's fragrance that helps you focus, alternative meat that's better for the planet, or reducing sugar without losing flavor, this is where you help shape the future of nutrition, health, and beauty for everyone, everywhere. And while you're making a difference, we'll make sure you're growing too. With learning that never stops, a culture that lifts you up and the freedom to move across businesses, teams, and borders. Your voice matters here. And your ideas? They're essential to our future. Because real progress only happens when we **go beyond, together** . **The application process** Interested in this position? Please apply online by uploading your resume in English by December 15, 2025. **Inclusion, belonging and equal opportunity statement** At dsm-firmenich, we believe being a force for good starts with the way we treat each other. When people feel supported, included, and free to be themselves, they do their best work - and that's exactly the kind of culture we're building. A place where opportunity is truly equal, authenticity is celebrated, and everyone has the chance to grow, contribute, and feel they belong. We're proud to be an equal opportunity employer, and we're serious about making our hiring process as fair and inclusive as possible. From inclusive language and diverse interview panels to thoughtful sourcing, we're committed to reflecting the world we serve. We welcome candidates from all backgrounds - no matter your gender, ethnicity, sexual orientation, or anything else that makes you, you. And if you have a disability or need any support through the application process, we're here to help - just let us know what you need, and we'll do everything we can to make it work. **Agency statement** We're managing this search directly at dsm-firmenich. If you're applying as an individual, we'd love to hear from you. We're not accepting agency submissions or proposals involving fees or commissions for this role
    $97k-139k yearly 32d ago
  • Senior Food Scientist

    Schweid 4.0company rating

    Senior principal scientist job in East Rutherford, NJ

    & Sons: Schweid & Sons is a family-owned and operated premium ground beef company with a proud heritage spanning four generations. We supply top-quality beef to Retail, Foodservice, and National Account customers across the U.S. and are committed to quality, customer service, and innovation in protein manufacturing. Summary: Are you a creative and driven professional with a passion for developing innovative premium protein products? Schweid and Sons is looking for a Food Scientist to add to our team. Reporting to the Director of Innovation, you will lead innovation and product development projects and initiatives, formulation, process improvement, ingredient, recipe and nutritional development, and provide food science strategy and guidance to take the company into the future. This role focuses on developing, improving, and ensuring the safety and quality of premium protein products, from fresh cuts to processed meats. The ideal candidate will have an understanding of meat science, food safety regulations, and product development processes within the beef and other protein industries. To be successful in this role, you must have strong food science, product development experience in protein, ability to improve and build repeatable processes, experience in meat operations, and knowledge of regulatory requirements. You should be comfortable leading key projects, working independently to ensure deadlines are met while balancing priorities. This is an incredible opportunity to join a well-established food manufacturing company that prides itself on putting its team members first by providing an incredible culture, amazing benefits, and commitment to innovation. Job Functions /Responsibilities: * Manage innovation projects, communicate, and coordinate with internal stakeholders as well as customers. Research and develop new products, including raw, fresh, cooked, cured, and value-added items. * Improve existing products in terms of taste, texture, shelf life, yield, and nutritional profile. * Design and conduct experiments on meat formulations, marination, cooking processes, and preservation techniques. * Organize sensory panels and conduct rigorous product testing to ensure we deliver a great tasting product. * Ensure all products comply with USDA, FDA, HACCP, and company food safety standards. * Conduct shelf-life testing and sensory evaluations of beef products. * Analyze raw materials and finished products for microbial, chemical, and physical properties. * Collaborate with procurement, QA, production, and marketing teams to bring new products to market. * Monitor trends in meat science, consumer preferences and processing technologies. * Prepare responses to customer inquiries with adequate scientific and technical evidence and provide solutions. * Complete the verification of the implementation of standard operating procedures for the laboratory or kitchen facilities. * Responsible for maintaining accurate records of formulations, procedures, and processes in appropriate software systems and platforms. Qualifications / Experience: * Bachelor's degree in Food Science or related field or equivalent experience. * USDA, FDA, HACCP and SQF experience. * 3 - 5 + years of Food Science in the protein category required. * 2 + years related protein experience required, preference for beef experience. * Food/nutrition manufacturing experience required. * Fundamental understanding of regulatory compliance and nutritional calculation software. * Understanding of daily lab and production processes. Expertise in raw material handling and stability. * Ability to independently formulate products based on consumer and customer requirements, identifying potential issues and promptly alerting managers or customers. Experience in food concept development and prototype improvement. * Some culinary and recipe development experience is a plus. * Able to effectively analyze data to develop presentations and reports. * Must be proficient in the use of Microsoft Office (Excel, Outlook, Word, and PowerPoint). What We Offer * The expected compensation for this role is $90,000 - $120,000 per year, depending on experience and qualifications. Final compensation will be discussed during the interview process. * Time Off: PTO, Safe & Sick Time, and Paid Holidays. * Health Benefits: Medical, vision, dental, HRA and voluntary disability benefits. * Financial Benefits: 401(k) + employer match and life insurance. * Location: This is an on-site role located in either East Rutherford, NJ or College Park, GA. * Environment: Office environment.
    $90k-120k yearly 25d ago
  • Bench Scientist

    Artech Information System 4.8company rating

    Senior principal scientist job in Pearl River, NY

    Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • We are looking for a highly motivated, detail oriented scientist to support antibody drug conjugate (Client) and targeted immunotherapy drug discovery at Pharmaceutical Oncology (ORU) in Pearl River, NY. • The successful candidate will work in a matrixed team environment as part of the Oncology Rinat Research & Development (ORRD) Histology & Biomarker (OHB) group. • The candidate will work as part of a team that uses histology and immunohistology methods to study protein/target expression, biomarker development, pharmacodynamics, efficacy and safety effects of molecules/compounds in development. • The successful candidate will be responsible for receiving and data basing the incoming pipeline of samples, and will be responsible for essential histological lab processes such as trimming, processing, sectioning and H&E staining of tissues. • The successful candidate will also be responsible for entering data into databases and maintaining lab organization, including ordering and maintenance of supplies and reagents. • Although prior histology experience is a significant plus, the successful candidate will at minimum have an understanding of cell biology and the scientific method, and will have had experience in a laboratory setting. • Furthermore the candidate will be flexible and be able to adapt to change as the lab is in a dynamic research environment, responding to the needs of the ORRD unit. • The successful candidate will be enthusiastic, energetic, able to follow instructions, detail oriented, agile to change, and will be an excellent and honest communicator. • The successful candidate will be expected to maintain an electronic laboratory notebook, use email, and meet weekly with the group manager - therefore basic computer skills are required such as Microsoft Outlook and Office (Excel, PowerPoint). Qualifications • Bachelor degree with minimum 2 years academic or industrial (pharmaceutical or biotech) research experience. • Experience in histology a significant plus but not necessarily required. Experience and knowledge of Microsoft Excel, PowerPoint. Additional Information Best Regards, Anuj Mehta ************
    $73k-105k yearly est. 60d+ ago
  • AI Research Scientist (AI Agents) - Senior Associate

    Jpmorgan Chase & Co 4.8company rating

    Senior principal scientist job in New York, NY

    JobID: 210676234 JobSchedule: Full time JobShift: Base Pay/Salary: New York,NY $137,750.00-$195,000.00 The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Scientist Senior Associate in J.P. Morgan AI Research, you will work on novel techniques, tools, and frameworks to model and solve complex large-scale problems, collaborating with experts in AI Agents and contributing to high-impact business applications and the broader AI community. Your role involves formulating problems, generating hypotheses, developing algorithms and models, conducting experiments, and communicating research significance. Your output will result in publications, high-impact business applications, open-source software, and patents. Job responsibilities * Work on multiple research projects in collaboration with internal and external researchers and applied engineering teams * Formulate problems, generate hypotheses, develop new algorithms and models, conduct experiments, synthesize results, gather data, build prototypes, and communicate research significance * Contribute to publications in AI/ML conferences and journals, high-impact business applications, open-source software, and patents * Participate in relevant top-tier academic conferences, organize workshops, and engage with the AI research community to broaden the impact of your contributions Required qualifications, capabilities, and skills * PhD in Computer Science, Statistics, Engineering, or related fields * Programming skills in Python * Proficient understanding of fundamental AI and ML techniques (e.g., A*, regularization) * Practical experience with statistical data analysis and experimental design * Curiosity, creativity, resourcefulness, and a collaborative spirit * Effective verbal and written communication skills with technical and business audiences * Demonstrated ability to work on multi-disciplinary teams with diverse backgrounds * Interest in problems related to the financial services domain Preferred qualifications, capabilities, and skills * Research publications in prominent AI/ML or Software Engineering venues (e.g., conferences, journals) * Strong expertise in specialized areas such as deep learning (DL) or AI Agents * Practical experience with ML platforms such as TensorFlow/Keras, PyTorch * Comfort with rapid prototyping and disciplined software development processes * Practical software engineering experience in collaborative project settings * Hands-on experience developing and using AI Agents in a professional setting
    $137.8k-195k yearly Auto-Apply 60d+ ago
  • Research Scientist

    Dyania Health

    Senior principal scientist job in Jersey City, NJ

    Role Description: Are you looking for a new career opportunity that will allow you to develop and use cutting-edge AI technologies to solve challenging NLP problems while making a positive impact on the world? If so, we would love to hear from you! Dyania Health is looking for Research Scientists to help us transform the way in which machines process biomedical information, and revolutionize the way in which clinical trials are conducted. You will be working alongside team members with deep technical expertise in NLP, top medical professionals (MDs, pharmacology PhDs, and others), and an experienced product team. The ideal candidate will have strong foundations in computer science and ML/NLP, superb communication skills, and a proven track record of delivery under tight deadlines. Requirements Required Qualifications: Graduate degree in a relevant field (Computer Science, Mathematics, Electrical Engineering) 2+ years experience in building and deploying ML models Experience in applying transformer-based deep-learning techniques to challenging NLP problems Fluency in Python and experience with Python-based ML frameworks such as PyTorch Outstanding communication skills Preferred Qualifications: Publications in top-tier NLP conferences Background in classical computational linguistics Experience with Java (or Kotlin/Scala) and/or a functional programming language Responsibilities: Design, build, evaluate, and deploy algorithms and models for accurately extracting medical information from structured and unstructured data sources Work closely with product, UX, and clinical teams to prototype and test new functionality Analyze performance results and convey your analyses to relevant stakeholders Conduct research, publish and present your findings at relevant scientific venues Team Culture: • We lead with empathy for patients and our teammates. • We value small egos, self-awareness, and humility in our teammates. • We appreciate flexible and adaptive attitudes towards solving problems, as strategic priorities may shift. • We love diversity of thought, perspective, working style, skill set, knowledge, and interests amongst our team. • We value open dialogue and brainstorming across multidisciplinary teams. Dyania Health is an equal opportunity employer that is committed to workplace diversity and inclusion. We do not discriminate on the basis of race, gender, gender identity, color, religion, national origin, sexual orientation, or any other legally protected characteristic as outlined by federal, state, or local laws.
    $75k-113k yearly est. Auto-Apply 60d+ ago
  • AI Research Scientist (AI Agents) - Senior Associate

    JPMC

    Senior principal scientist job in New York, NY

    The Chief Data & Analytics Office (CDAO) at JPMorgan Chase is responsible for accelerating the firm's data and analytics journey. This includes ensuring the quality, integrity, and security of the company's data, as well as leveraging this data to generate insights and drive decision-making. The CDAO is also responsible for developing and implementing solutions that support the firm's commercial goals by harnessing artificial intelligence and machine learning technologies to develop new products, improve productivity, and enhance risk management effectively and responsibly. As an AI Research Senior Associate in J.P. Morgan AI Research, you will work on novel techniques, tools, and frameworks to model and solve complex large-scale problems, collaborating with experts in AI Agents and contributing to high-impact business applications and the broader AI community. Your role involves formulating problems, generating hypotheses, developing algorithms and models, conducting experiments, and communicating research significance. Your output will result in publications, high-impact business applications, open-source software, and patents. Job responsibilities Work on multiple research projects in collaboration with internal and external researchers and applied engineering teams Formulate problems, generate hypotheses, develop new algorithms and models, conduct experiments, synthesize results, gather data, build prototypes, and communicate research significance Contribute to publications in AI/ML conferences and journals, high-impact business applications, open-source software, and patents Participate in relevant top-tier academic conferences, organize workshops, and engage with the AI research community to broaden the impact of your contributions Required qualifications, capabilities, and skills PhD in Computer Science, Statistics, Engineering, or related fields Programming skills in Python Proficient understanding of fundamental AI and ML techniques (e.g., A*, regularization) Practical experience with statistical data analysis and experimental design Curiosity, creativity, resourcefulness, and a collaborative spirit Effective verbal and written communication skills with technical and business audiences Demonstrated ability to work on multi-disciplinary teams with diverse backgrounds Interest in problems related to the financial services domain Preferred qualifications, capabilities, and skills Research publications in prominent AI/ML or Software Engineering venues (e.g., conferences, journals) Strong expertise in specialized areas such as deep learning (DL) or AI Agents Practical experience with ML platforms such as TensorFlow/Keras, PyTorch Comfort with rapid prototyping and disciplined software development processes Practical software engineering experience in collaborative project settings Hands-on experience developing and using AI Agents in a professional setting
    $65k-98k yearly est. Auto-Apply 60d+ ago
  • Machine Learning Research Scientist

    Smarterdx

    Senior principal scientist job in New York, NY

    Role As a Machine Learning Research Scientist, you will lead groundbreaking ML research and development at SmarterDx, collaborating closely with experienced engineers and clinicians to turn your inventions into enterprise-grade products. With minimal supervision, you will establish a research agenda informed by emerging trends in AI, develop and rigorously evaluate your proposed algorithms, deploy your algorithms into production, and monitor impact. You will collaborate closely with other machine learning research scientists to identify the most promising areas of AI/ML R&D for SmarterDx and establish shared infrastructure to accelerate research efforts across the team. What You'll Do * 45% Hands-on implementing new methods and relevant baseline models (ML Research) * 20% Working cross-functionally to deploy models into production (MLOps, MLE) * 20% Data Science (data engineering, dataset curation, experimental design, model updates, product domain expertise) * 15% Academics & Outreach (e.g., scientific reading & writing, publishing, presenting at conferences, recruiting) * Become a domain expert at clinical data and the healthcare ecosystem * Own end to end model development including deployment into production and production monitoring, learning Machine Learning Operations (MLOps) * Post training to align large language models (LLMs) on proprietary clinical data * Develop new self-supervised pre-training tasks for improving models * Develop novel retrieval, attribution and hallucination detection strategies for generative models * Develop novel methods for explaining and summarizing diagnostic classifications * Develop methods for selecting data sources to include in training (data-centric AI) * Develop novel graph-based algorithms for improving classification of diseases and procedures with few or no labels * Develop novel methods for multimodal data fusion (structured and unstructured data) * Long-sequence language modeling What You Bring * Desire to translate research into tangible positive impact by deploying research into production engineering systems (MLOps) * With scientific concepts, technical debugging or domain knowledge, ability and desire to communicate clearly and proactively when conveying or receiving * Deep "under-the-hood" understanding of modern neural network architectures and distributed training. ie knows the differences between SwiGLU vs. sigmoid, GRUs vs. transformers vs SSMs, encoders vs. decoders, masked language models vs. autoregressive language models, Megatron vs nanotron vs DeepSpeed * Extensive experience developing, implementing and training state-of-the-art deep learning models using multiple GPUs and nodes if necessary for large language models with frameworks such as PyTorch, JAX, etc * Ability to assess, understand and create high-quality machine learning research, as demonstrated through publications at top-tier conferences and journals (e.g., NeurIPS, ICML, ICLR, ACL, EMNLP, SIGIR, AAAI, NEJM AI, JAMIA, npj Digital Medicine, ar Xiv) Nice To Haves * MLSys skills ie knows the differences between tensor vs pipeline vs data parallelism, gloo vs mpi vs nccl, CUDA vs ROCm, Triton vs ThunderKittens * Familiarity with inference optimizations, ie vLLM, SGLang, continuous batching, KV Caching, speculative decoding Our Tech Stack * PyTorch, Python, GitHub, Snowflake, Huggingface Transformers, AWS Sagemaker, Microsoft DeepSpeed, TorchTune, Apache Airflow, SLURM, Kubernetes Compensation $200-220k base salary + equity incentives #LI-Remote
    $62k-93k yearly est. Auto-Apply 60d+ ago
  • Applied NLP Scientist

    Teleskope

    Senior principal scientist job in New York, NY

    Teleskope is building the future of data security. Despite enormous growth in awareness and investment in data security, most companies still don't know where they are storing sensitive information and how to secure it. At Teleskope, we're building a modern and developer-friendly data security platform to automate data security and privacy at scale, from detection to remediation. About the role Teleskope is looking for an Applied NLP Scientist to play a critical role in the evolution of our remediation engine, which powers our data security and privacy platform. In this role, you will lead the development of agentic NLP systems that don't just detect risks in unstructured data but take proactive remediation and compliance actions directly within the Teleskope platform. You will design and build intelligent agents that operate across diverse enterprise data modalities (e.g., unstructured text, documents, tables, images), unifying extraction, prediction, and decision-making into action-oriented pipelines. This role involves working with massive datasets and building production-grade ML infrastructure that supports fast, reliable, and scalable inference for real-time remediation. This is a high-impact, in-office role based in NYC where you'll collaborate across engineering, product, and customer-facing teams to bring remediation-focused AI agents to life. What you'll do Own and evolve the Teleskope remediation and classification pipeline across multiple data modalities (e.g., text, documents, tables, images). Build and maintain agentic systems that unify information extraction with automated action-taking workflows. Apply modern NLP and LLM-based techniques for classification, clustering, summarization, and agent-driven decision-making. Define and build processes for evaluation, validation, and continuous monitoring of models and agents. Collaborate with product and engineering teams to integrate AI-driven remediation agents into customer-facing workflows. Stay on top of research and best practices in applied NLP, LLMs, and agentic architectures, contributing to the evolution of our ML stack. What you bring 4+ years of experience in applied NLP. Demonstrated success building and deploying LLM pipelines, agentic systems, or applied NLP models in production. Experience across the ML lifecycle: data preprocessing, model training, evaluation, and deployment. Bachelor's, Master's, or PhD in Computer Science, Computational Linguistics, or related field-or equivalent experience. Excellent communication and collaboration skills. Must be based in New York City-this is an in-office role. What you'll get An opportunity to join an early stage startup in one of today's fastest growing markets Space to build impactful features and own projects from start to finish Room to learn, grow, and rapidly advance in your data scientist career A beautiful, well-stocked office in NYC's Financial District Competitive salary and meaningful equity Health, vision, dental, 401k and more benefits, heavily subsidized by Teleskope What we value At Teleskope, we value technical excellence, practical execution, and a strong sense of ownership. We're looking for team members who bring domain expertise and a passion for shipping impactful ML solutions that meet real-world privacy and security needs.
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • ML Scientist

    Layer Health

    Senior principal scientist job in New York, NY

    Layer Health was founded in 2023 by leading machine learning researchers from MIT and Harvard Medical School. We are building an AI layer that can accurately and scalably synthesize information from medical records, with the mission to reduce friction everywhere in healthcare. Our LLM-powered platform is solving chart review once and for all, across use cases. For health systems, our first product dramatically accelerates clinical registry abstraction in areas ranging from surgery and cardiology, to oncology. Our long term vision is for our AI layer to safely transform patient care and minimize unnecessary heartbreak. Layer Health's diverse founding team brings expertise across machine learning, UI/UX, large language models, and medicine. We're seeking outstanding hires to join our team as early members. This is an opportunity to contribute to a high-impact, collaborative, mission-driven team, and help define the next stage of growth for Layer Health. Together, we will create the AI layer that will redefine healthcare for the better. Here's a collection of articles about our product, mission, recent funding round, etc. Job Description We're hiring an exceptional ML scientist. In this role, you will be responsible for pioneering innovative machine learning techniques to advance our fundamental clinical machine learning and large language model efforts. You can expect to: Design and implement state-of-the-art machine learning techniques to advance Layer Health's research agenda (in areas such as information extraction, multimodal reasoning, and summarization). Propose new agentic methods that tackle fundamental NLP and ML challenges such as modeling over multiple documents, long contexts, multiple modalities, and with limited or noisy labels Build foundation models to power the future of clinical information extraction & synthesis, from training through inference. Stay up-to-date and actively engage with cutting-edge research in NLP, generative AI, and clinical machine learning. Collaborate with the broader engineering team to ship performant products that meet user needs. Cultivate and foster a robust and thoughtful R&D culture that drives the company forward. We look for: Exceptional methodological research background and experience, including but not limited to: A PhD in computer science/applied mathematics or equivalent research experience, specializing in natural language processing and machine learning. High-impact, early-author publications at top peer-reviewed ML journals/conferences. Demonstrated record of delivering real-world impact from start to finish- with the ability to design, develop, and ship innovations. Strong programming skills and fluency with modern machine learning/LLM stacks (deep learning libraries e.g. PyTorch, Jax). Past experience in training/inference of foundation models (billions of parameters, distributed training, familiarity with state-of-the-art techniques). A strong communicator who thrives in a customer-focused, fast-paced environment. An excited and adaptable team player who wants to disrupt the healthcare industry with AI/ML, alongside an awesome team. Past experience in healthcare of life sciences is a plus, but not required. We are a Boston-based company, and expect employees to meet regularly in-person in Boston (employees from Boston, NYC, or east coast are welcome). Expected compensation range for this role is $200,000-250,000, in addition to stock options. Compensation is dependent on experience, overall fit to our role, and candidate location. Expected compensation ranges for this role may change over time. If your compensation requirement is greater than our posted salary ranges, please still consider applying to our role. We will make a determination as to whether an exception can be made. If you are excited about this role, we encourage you to apply even if you don't feel that you meet every single requirement. We're eager to meet people that believe in our mission and can contribute to our team in a variety of ways. We welcome diverse perspectives, rigorous thinking, and fearlessness in challenging the status quo. Layer Health is committed to fostering an environment of inclusion that is free from discrimination. We are an Equal Opportunity Employer where employment is decided on the basis of qualifications, merit, and business need. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected Veteran status, or any other characteristic protected by law. Join us and help us transform healthcare with AI.
    $66k-97k yearly est. Auto-Apply 35d ago
  • Applied Scientist, Prime Video - Content Understanding

    Prime Video

    Senior principal scientist job in New York, NY

    Prime Video is a first-stop entertainment destination offering customers a vast collection of premium programming in one app available across thousands of devices. Prime members can customize their viewing experience and find their favorite movies, series, documentaries, and live sports - including Amazon MGM Studios-produced series and movies; licensed fan favorites; and programming from Prime Video add-on subscriptions such as Apple TV+, Max, Crunchyroll and MGM+. All customers, regardless of whether they have a Prime membership or not, can rent or buy titles via the Prime Video Store, and can enjoy even more content for free with ads. Are you interested in shaping the future of entertainment? Prime Video's technology teams are creating best-in-class digital video experience. As a Prime Video technologist, you'll have end-to-end ownership of the product, user experience, design, and technology required to deliver state-of-the-art experiences for our customers. You'll get to work on projects that are fast-paced, challenging, and varied. You'll also be able to experiment with new possibilities, take risks, and collaborate with remarkable people. We'll look for you to bring your diverse perspectives, ideas, and skill-sets to make Prime Video even better for our customers. With global opportunities for talented technologists, you can decide where a career Prime Video Tech takes you! For examples of our work, please see a selection of our publications from ECCV, ICCV and ICLR: • ********************************************************************************************************************************** • **************************************************************************** • ************************************************************************************************************************ Key job responsibilities As an Applied Scientist, your day-to-day responsibilities will include: Defining technical strategy: You will collaborate with other leaders in Prime Video to define the problem we will solve long-term to serve customers. You will formulate our science and engineering strategy for achieving this vision. Execution: You will be at the forefront in bring the strategy to life. You will directly deliver key components of our science and research roadmap. You will act as a force-multiplier for other scientists in the team. Developing Others: You will mentor and coach junior scientists in the team. You will drive scientific and technical best practices for others and elevate the quality of the output produced by the entire team. About the team Our Prime Video Content Understanding team builds holistic media representations (e.g. descriptions of scenes, semantic embeddings) and apply them to new customer experiences supply chain problems. Our technology spans the entire Prime Video catalogue globally, and we enable instant recaps, skip intro timing, ad placement, search, and content moderation. As an Applied Scientist in our Content Understanding Team, you will lead the end-to-end research and deployment of multi-modal models applied to a variety of downstream applications. We are seeking a science leader with deep knowledge of multi-modal content understanding, including Vision Language Models (VLMs) and Multi-Modal Language Models (MMLMs). - PhD, or Master's degree and 4+ years of CS, CE, ML or related field experience - 3+ years of building models for business application experience - Experience programming in Java, C++, Python or related language - Experience using Unix/Linux - Experience in professional software development Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status. Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit ********************************************************* for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner. Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $136,000/year in our lowest geographic market up to $223,400/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit ******************************************************** This position will remain posted until filled. Applicants should apply via our internal or external career site.
    $66k-97k yearly est. 60d+ ago
  • Scientist II, Immuno-Oncology

    Cellectis

    Senior principal scientist job in New York, NY

    Scientist II, Immuno-Oncology FUNCTIONAL AREA: REPORTS TO: Team Leader EXEMPT/NON-EXEMPT In the Immuno-Oncology team, we are looking for an enthusiastic, inventive and team-oriented scientist to join us in the creation cutting-edge cellular treatments for cancer and other serious diseases. We are looking for colleagues with a strong background in one or multiple areas including: Immuno-Oncology, Oncology or Immunology, and who possess strong expertise in T-cell biology, intricate multicolor flow cytometry, and in vivo mouse models. The ideal candidate would have a remarkable scientific record, excellent communication and interpersonal abilities, be passionate about scientific research, and excel at pushing boundaries for innovation. We value candidates who are adept at problem-solving and approach difficulties with optimism. The chosen individual will join a dynamic, creative and goal-oriented atmosphere dedicated to making impactful advances in the way we treat disease. Responsibilities Responsibilities include, but are not limited to: Develop innovative adoptive cell therapies to treat cancer or other serious diseases. Design, execute, and analyze in vitro experiments (some examples include engineering of CAR T-cells, cytotox, ELISA, proliferation assays, flow cytometry analysis, cell culture). Design, execute and analyze in vivo preclinical studies (some examples of procedures include tumor implantation, adoptive cell therapy administration, mice dosing through different administration routes, tumor monitoring, blood collection and multiple tissue analysis). Efficiently and clearly present and communicate scientific data to the team, cross-functionally and at external meetings. Pro-actively suggest and evaluate innovative cell engineering solutions and develop new assays to enhance the company's intellectual portfolio and contribute to peer-reviewed publications. Stay up to date with external scientific research from academic and industry institutions. Keep timely detailed documentation of experiments. Effectively plan and manage projects and deliverables to meet deadlines. Foster cross-functional collaborations and train other colleagues. Prioritize company objectives and work towards shared success. Other duties as necessary to ensure the daily operations of the lab and support the team. Core Competencies Keen eye for detail, exceptional problem-solving abilities, and a commitment to producing robust and high-quality scientific data for internal/external reports, publications and IND-enabling studies Strong scientific creativity and analytical thinking skills. Curiosity and drive to initiate and advance programs to treat diverse important diseases. Excellent written, oral and interpersonal communication skills. Capable of adhering to SOP and develop new protocols. Works well autonomously and collaboratively with other team members and cross-functionally. Flexibility and ability to adapt positively to a dynamic environment with changing priorities. Pro-active, transparent and adaptable team-player with a professional demeanor who works well under pressure. Comfortable operating in a fast-paced, small-midsized company environment. Requirements PhD in oncology, immunology, or equivalent (minimum of 3 years of experience after PhD in related role). Experience in human T-cell biology, immuno-oncology and knowledge in cell engineering technologies. Hands on experience and troubleshooting proficiency in immunology assays including immune cell isolation, multicolor flow cytometry, immune cell and cytokine profiling assays using conventional and next-generation analytical methods. Demonstrated experience designing and executing mouse tumor model experiments including mouse handling (injections- IV, SC, IP- and organ dissection). Excellent abilities to analyze and synthesize data for different audiences and report types while supporting decision-making processes. Proficiency in molecular biology as well as analyzing and manipulating DNA/protein sequences using bioinformatics software is desired. Basic knowledge of gene editing and next-generation sequencing technologies is a plus. Experience in working in matrixed environments and in project management is desired. Strong record of scientific publications and demonstrated scientific curiosity. Willingness to quickly adapt, innovate, discover new approaches, collaborate and support the team towards shared company goals. Candidates should be authorized to work in the U.S., preferably without the need for current, or future, sponsorship. Role is onsite and based in New York, NY Physical Requirements Sedentary - primarily involves sitting and/or standing. Laboratory work performed within a BSL1 and BSL2 environments. Communicates with others daily to exchange information. Salary Range (105,000 to 115,000 USD), dependent on skills and experience
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • Machine Learning Scientist

    Inductive Bio

    Senior principal scientist job in New York, NY

    Drug discovery is a prediction problem. Scientists design molecules that they predict will be potent, safe, and readily absorbed into the body, but ultimately lab experiments must be run to know whether these predictions are accurate. Each one of these experiments can take weeks or months to run, and as a result it costs millions of dollars and takes years to design a molecule that is ready for testing in humans. At Inductive Bio, we're using AI to build in silico models that can more accurately predict how molecules will behave in experiments. By predicting complex molecular properties directly from the molecular structure, our platform helps scientists make better decisions faster-ultimately bringing safer, higher-quality medicines to patients more quickly. We are enabled by a unique and growing proprietary data set, and we are already applying our methods to dozens of active drug discovery programs. Backed by leading investors at the intersection of biotechnology and technology and advised by renowned experts in drug discovery, we are growing rapidly and poised to make a major impact in drug discovery. We are seeking Machine Learning Scientists to join our talented, ambitious, and kind team. You'll have the opportunity to innovate on methods, work with leading drug discovery scientists, and apply your work immediately to drug programs at some of the most innovative biotechs in the world. As an early machine learning scientist at a rapidly-growing startup, you'll have the opportunity for high impact while learning and growing with the company. What you'll do: Develop machine learning models to predict molecular properties from chemical structures Develop novel algorithms for generating ideas for new molecules Build agents that can synthesize complex information from drug programs and apply that information strategically toward molecular optimization Get your hands dirty by diving deep into our unique, proprietary dataset to iterate on modeling ideas and improve model performance Collaborate closely with chemists and software engineers to integrate models into our software platform, which is used by drug discovery scientists across the industry Build and optimize scalable infrastructure for model training, deployment, and monitoring Engage directly with our scientific users, incorporating their feedback into the product Contribute meaningfully to product strategy and company direction Who you are: You have 4+ years of experience as a Machine Learning Scientist, Machine Learning Engineer, Data Scientist, or similar role You have expertise in machine learning fundamentals, deep learning architectures, and evaluation approaches You are proficient in standard Python-based ML frameworks (e.g. PyTorch, TensorFlow, scikit-learn) You are comfortable writing high-quality, reusable code and productionizing models for serving in the cloud You are excited to dive deep into the science and practice of drug discovery You have exceptional written and oral communication skills Working at Inductive At Inductive Bio, we know that the people on the team are what make us great. We offer competitive salary and equity-based compensation; comprehensive healthcare benefits (including dental and vision); and the opportunity to grow along with a rapidly scaling company. We are a passionate, kind, and mature team. Working at a fast growing startup is not always a 9-5 job, but we believe that our employees should have full lives beyond their career.
    $66k-97k yearly est. Auto-Apply 60d+ ago
  • Associate Research Scientist | Functional Genomics

    Jackson Laboratory 4.3company rating

    Senior principal scientist job in New York, NY

    JAX/NYSCF is seeking an Associate Research Scientist to join the Functional Genomics team as part of the NYSCF Global Stem Cell Array, a robotic system that automates both iPSC derivation, gene editing, and downstream differentiations. The Associate Research Scientist will contribute to an innovative project centered on phenotyping cardiomyocytes derived from genetically diverse human induced pluripotent stem cell (hi PSC) lines. This work aims to uncover the genetic basis of cardiotoxic responses and to advance predictive models of cardiovascular health through high-throughput functional screening, transcriptomics, and metabolomics. The project is highly collaborative, involving multidisciplinary teams across several institutions. The primary focus of the work you'll do at JAX/NYSCF is developing automated protocols for the derivation/culture of iPSC-derived cardiomyocytes, drug testing, and sample preparation for downstream analyses, including imaging and single-cell sequencing. We want candidates with extensive expertise in human pluripotent stem cell culture, directed differentiation into cardiomyocytes, and functional assays. Experience with cell culture automation (including liquid handling systems) or high-throughput assays is a major plus. This role offers a unique opportunity to work with state-of-the-art screening technologies and automated platforms while contributing to impactful translational research in cardiac safety pharmacology and personalized medicine. As a Associate Research Scientist on the Functional Genomics team, you will: * Design, optimize, and execute experiments to advance a high-throughput iPSC-derived cardiomyocyte platform * Culture and expand iPSCs, generate iPSC-derived cardiomyocytes, and assess cardiomyocyte quality using automated liquid handling systems * Apply strong scientific knowledge and analytical skills to monitor, troubleshoot, and refine experimental workflows in real time. * Independently conduct literature reviews to identify and propose innovative experimental methods, procedures, or technologies * Contribute to project planning by preparing budgets, timelines, and resource estimates for supplies and equipment * Lead multiple, concurrent project components, ensuring progress toward research goals * Evaluate and document results, adapt methodologies as needed, and maintain compliance with regulatory standards * Communicate research goals and findings effectively, guiding team members and informing collaborators on past and future directions * Coordinate with external partners to explore new research opportunities Foster a collaborative environment by sharing expertise and demonstrating openness to learning from others Minimal requirements * PhD +3 years of work experience in Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline. * Experience with induced pluripotent stem cells or cardiomyocytes/ iPSC-derived cardiomyocytes. * Strong communication skills, with the ability to clearly explain research findings and methodologies in both written and verbal formats, as well as effectively discuss, troubleshoot, and resolve experimental challenges with team members and collaborators. * Ability to follow and adapt protocols accurately. * Excellent documentation and data management practices. Preferred experience: * Experience in differentiation of iPSC culture in cardiovascular lineages. * Exposure to automated cell culture systems (liquid handlers) * Electrophysiology experience is a plus * Flow cytometry Please submit a Cover Letter and CV for application consideration. Pay Range: $65018 - $108857 per year, dependent upon experience. About JAX: The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit ************ EEO Statement: The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
    $65k-108.9k yearly Auto-Apply 60d+ ago

Learn more about senior principal scientist jobs

How much does a senior principal scientist earn in Yonkers, NY?

The average senior principal scientist in Yonkers, NY earns between $74,000 and $144,000 annually. This compares to the national average senior principal scientist range of $83,000 to $169,000.

Average senior principal scientist salary in Yonkers, NY

$103,000

What are the biggest employers of Senior Principal Scientists in Yonkers, NY?

The biggest employers of Senior Principal Scientists in Yonkers, NY are:
  1. Regeneron
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