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  • Principal Scientist (Residual Impurities)

    MacRogenics, Inc. 4.8company rating

    Senior scientist job in Rockville, MD

    Job Category: Development Apply now Posted : November 5, 2025 Full-Time On-site Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe. The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization. Summary of Position The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams. Responsibilities and Job Duties: Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release. Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness. Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations. Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts. Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders. Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions. Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support. Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays. Author and/or review SOPs, technical protocols and reports, and regulatory filings. Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership. Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences. Participate in industry consortia on relevant topics and align internal strategies with industry practice. Qualifications Education & Experience Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development; or Master's degree with 12+ years of related industry experience; or Bachelor's degree with 14+ years of related industry experience 2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams Prior experience in preparing analytical sections of IND, BLA and regulatory responses. Knowledge, Skills and Abilities Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA) Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment Skilled in stakeholder management, with clear, proactive, and collaborative communication style Strong technical writing skills and attention to detail in documentation and data review Experience mentoring and developing scientific staff; promotes open communication and teamwork Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines. Demonstrated leadership and influence in cross‑functional matrix environments Preferred Qualifications Familiarity with potency assays, physiochemical assays and other characterization assays Knowledge in novel techniques on detecting and analyzing residual impurities Strong publication record and external scientific presence Experience in fostering partnership with clients through CDMO service Supervisory Responsibilities Yes. This role may supervise Associate Scientist and/or Scientist Additional Information The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits. The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law. Statement MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies. #J-18808-Ljbffr
    $129.5k-197.5k yearly 4d ago
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  • Chief Scientist - Earth Science Modeling

    National Science Teachers Association 4.0company rating

    Senior scientist job in Silver Spring, MD

    ERT is seeking a Chief Scientist with experience in meteorology or atmospheric sciences, or other earth sciences to support tasks at National Oceanic and Atmospheric Administration's (NOAA) Earth Prediction Innovation Center (EPIC). The primary objective will be to enhance the research-to-operations-to-research pipeline for the weather forecasting community with the goal of improving the overall accuracy and reliability of US National Weather Service weather models. All research and development will be guided by the NOAA open‑source science principles. Required Skills 15+ years of experience in position of increasing responsibility and leadership in the field of climate or earth systems science, weather modeling and forecasting, or a closely related discipline. Facility with the computational and technical operational components of handling and using earth systems data for large-scale forecasting. Must be able to pass a background investigation to obtain a security badge to enter the applicable government facility. Education MS degree in atmospheric science, earth science or closely related discipline. PhD preferred. Location This position supports work at NOAA's Silver Spring, MD facility with some telework permitted. Compensation The salary range for this role is $46,000 - 221,000/year. This range is a good faith estimate based on similar roles across the organization. ERT considers several factors when extending an offer of employment, including the location, scope, and associated responsibilities of the specific position, as well as a candidate's work experience, education/training, and key skills. Benefits All full‑time employees are eligible to participate in our flexible benefits package, which includes: Medical, Rx, Dental, and Vision Insurance 401(k) retirement plan with company‑matching 11 Paid Federal Government Holidays Paid Time Off (PTO) Basic Life & Supplemental Life Health Savings Account, Flexible Spending and Dependent Care Flexible Spending Accounts Short‑Term & Long‑Term Disability Employee assistance program (EAP) Tuition Reimbursement, Personal Development & Learning Opportunities Skills Development & Certifications Professional Membership Reimbursement Employee Referral Program Competitive compensation plan Discretionary variable incentive bonuses based on factors such as individual performance, business unit performance, and/or the company's performance Publication and Conference Presentation Awards with bonuses ERT is a VEVRAA Federal Contractor and Equal Opportunity Employer - All qualified applicants will be considered for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status. #J-18808-Ljbffr
    $46k-221k yearly 1d ago
  • Principal Associate, Data Scientist - LLM Customization Team

    Capital One National Association 4.7company rating

    Senior scientist job in McLean, VA

    Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data‑driven decision‑making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description The LLM Customization team is on the cutting edge of GenAI and at the center of bringing our vision for AI at Capital One to life. The work of the AI Training Team touches every aspect of the model development life cycle and our deployed models in production drive business impact with visibility from our C‑Suite. Our team creates unprecedented amounts of high quality data for training and testing GenAI models; we care about how it's created, what's in those datasets, and the impact they have We are invested in building capabilities for evaluating and monitoring generative models; these methods must be state of the art, easy to use, and trusted by our users and contributors Horizontal capabilities enable vertical use case work; the team builds search, summarization, RAG, and agentic workflows for integration in production applications across the company We learn from our colleagues, attend conferences, publish papers, and maintain strong connections to the research community. In this role, you will: Partner with a cross‑functional team of data scientists, software engineers, machine learning engineers and product managers to deliver AI powered products that change how customers interact with their money. Leverage a broad stack of technologies - Pytorch, AWS Ultraclusters, Hugging Face, LangChain, Lightning, VectorDBs, and more - to reveal the insights hidden within huge volumes of numeric and textual data. Be the expert in Natural Language Processing (NLP) to harness the power of Large Language Models (LLMs), adapt and finetune them for customer facing applications and features. Build machine learning and NLP models through all phases of development, from design through training, evaluation, and validation; partnering with engineering teams to operationalize them in scalable and resilient production systems that serve 80+ million customers. Flex your interpersonal skills to translate the complexity of your work into tangible business goals. The Ideal Candidate is: Customer first. You love the process of analyzing and creating, but also share our passion to do the right thing. You know at the end of the day it's about making the right decision for our customers. Innovative. You continually research and evaluate emerging technologies. You stay current on published state‑of‑the‑art methods, technologies, and applications and seek out opportunities to apply them. Creative. You thrive on bringing definition to big, undefined problems. You love asking questions and pushing hard to find answers. You're not afraid to share a new idea. A leader. You challenge conventional thinking and work with stakeholders to identify and improve the status quo. You're passionate about talent development for your own team and beyond. Technical. You're comfortable with advanced ML and DL technologies including language models and are passionate about developing further. You have hands‑on experience working with LLMs and solutions using open‑source tools and cloud computing platforms. Influential. You are passionate about AI/ML and can bring along a cross functional team in breakthrough innovations. You communicate clearly and effectively to share your findings with non‑technical audiences. You are experienced in training language models or large computer vision models as well as have expertise in one or more key subdomains such as training optimization, self‑supervised learning, explainability, RLHF. You have an engineering mindset as shown by a track record of delivering models at scale both in training data and inference volumes. You have experience in delivering libraries, platforms, or solution level code to existing products. Basic Qualifications Currently has, or is in the process of obtaining one of the following with an expectation that the required degree will be obtained on or before the scheduled start date: A Bachelor's Degree in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) plus 5 years of experience performing data analytics A Master's Degree in a quantitative field or an MBA with a quantitative concentration plus 3 years of experience performing data analytics A PhD in a quantitative field (Statistics, Economics, Operations Research, Analytics, Mathematics, Computer Science, or a related quantitative field) Preferred Qualifications Master's Degree in “STEM” field (Science, Technology, Engineering, or Mathematics) plus 3 years of experience in data analytics, or PhD in “STEM” field (Science, Technology, Engineering, or Mathematics) At least 1 year of experience working with AWS At least 3 years' experience in Python, Scala, or R At least 3 years' experience with machine learning At least 3 years' experience with SQL Capital One will consider sponsoring a qualified applicant for employment authorization for this position. The minimum and maximum full‑time annual salaries for this role are listed below, by location. Please note that this salary information is solely for candidates hired to perform work within one of these locations, and refers to the amount Capital One is willing to pay at the time of this posting. Salaries for part‑time roles will be prorated based upon the agreed upon number of hours to be regularly worked. McLean, VA: $158,600 - $181,000 for Principal Associate, Data Science New York, NY: $173,000 - $197,400 for Principal Associate, Data Science San Jose, CA: $173,000 - $197,400 for Principal Associate, Data Science Candidates hired to work in other locations will be subject to the pay range associated with that location, and the actual annualized salary amount offered to any candidate at the time of hire will be reflected solely in the candidate's offer letter. This role is also eligible to earn performance based incentive compensation, which may include cash bonus(es) and/or long term incentives (LTI). Incentives could be discretionary or non discretionary depending on the plan. Capital One offers a comprehensive, competitive, and inclusive set of health, financial and other benefits that support your total well‑being. Learn more at the Capital One Careers website. Eligibility varies based on full or part‑time status, exempt or non‑exempt status, and management level. This role is expected to accept applications for a minimum of 5 business days. No agencies please. Capital One is an equal opportunity employer (EOE, including disability/vet) committed to non‑discrimination in compliance with applicable federal, state, and local laws. Capital One promotes a drug‑free workplace. Capital One will consider for employment qualified applicants with a criminal history in a manner consistent with the requirements of applicable laws regarding criminal background inquiries, including, to the extent applicable, Article 23‑A of the New York Correction Law; San Francisco, California Police Code Article 49, Sections 4901‑4920; New York City's Fair Chance Act; Philadelphia's Fair Criminal Records Screening Act; and other applicable federal, state, and local laws and regulations concerning criminal background inquiries. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation, please contact Capital One Recruiting at 1‑************ or via email at RecruitingAccommodation@capitalone.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodations. For technical support or questions about Capital One's recruiting process, please send an email to **********************. Capital One does not provide, endorse nor guarantee and is not liable for third‑party products, services, educational tools or other information available through this site. Capital One Financial is made up of several different entities. Please note that any position posted in Canada is for Capital One Canada, any position posted in the United Kingdom is for Capital One Europe and any position posted in the Philippines is for Capital One Philippines Service Corp. (COPSSC). #J-18808-Ljbffr
    $173k-197.4k yearly 2d ago
  • Research Scientist II (Infectious Disease Epidemiology Health Services Research)

    Mid-Atlantic Permanente Medical Group Careers

    Senior scientist job in Washington, DC

    Mid-Atlantic Permanente Medical Group (MAPMG) invites applications for the position of Research Scientist II (Infectious Disease Epidemiology/Health Services Research), which is an equivalent to an academic associate professor, to join the Mid-Atlantic Permanente Research Institute (MAPRI). This is a full-time position based in our regional office located in Capitol Hill, Washington D.C. with a hybrid work model. Reporting to the Director of Research Science, the Research Scientist II will design and implement major investigator-initiated health services and epidemiology-related research projects in the area of infectious diseases. You will also secure external funding through federal, foundation, or industry grants, and disseminate findings through peer-reviewed publications and conference presentations. The Research Scientist II may contribute to intramural projects relevant to MAPRI and MAPMG, providing assistance as needed for study design, analysis plans, and interpretation of results. Please note, this is not a basic research or bench science position. You can expect to: Develop an innovative research portfolio in infectious disease healthcare delivery and outcomes, working both independently and in collaboration with external partners, leveraging Kaiser Permanente's extensive clinical data Prepare and submit grant proposals and secure extramural research funding, aiming to achieve funding for 75-80% of annual effort within five years. Initiate and maintain collaborations with external partners, including federal agencies, other Kaiser Permanente regions, research networks, and academic or healthcare system partners. Publish one to two first-author papers and one to two collaborative papers annually, and present research findings (poster or oral) at national scientific meetings. Collaborate with MAPRI research teams (data analysts, project managers, and biostatisticians), leading research studies and ensuring they are completed successfully Mentor MAPMG staff, physician researchers, and research interns. Contribute to the scientific community through being a peer reviewer for journals (at least two per year) and participating in expert or grant review panels. What is required: MD/DO with an additional advanced research degree (e.g., MPH, MAS, MS, PhD) OR a PhD or equivalent degree in Epidemiology, Health Services Research, Nursing, or related discipline is required Extensive experience in infectious disease research Minimum of seven (7) years of post-doctoral research experience in epidemiology, health services research, or related field is required; experience in a health system research setting preferred Strong publication record in peer-reviewed journals Demonstrated ability to design and lead simultaneous original research studies and publish results. Successful track record of extramural grant funding as Principal Investigator Must be able to go into the regional office located in Capitol Hill, Washington D.C. at least quarterly, and on an as-needed basis Candidates must either currently live in or be willing to relocate to the Washington D.C., Maryland, or Virginia area Must provide documentation of the Covid vaccine 2-dose series (or J&J 1-dose) prior to October 1, 2023, or documentation for 1-dose of the most current Covid vaccine (Pfizer or Moderna) as a condition of employment. Must provide documentation for the influenza vaccine as a condition of employment. Competitive Benefits: Competitive compensation package 100% employer-funded medical and dental insurance premiums for employees and families Generous paid time off, including vacation, holidays, and sick leave, plus maternity and parental leave Pension plan, and 401(k) retirement plan with employer contributions Life insurance, short-term disability, and long-term disability coverage Education reimbursement The starting annual salary for this position ranges from $152,776.24 to $190,970.12 depending on circumstances including an applicant's skills and qualifications, certain degrees and certifications, prior job experience, training, market data, and other relevant factors. In addition to the salary range above, MAPMG offers rich benefits that add substantial value to the total compensation package. MAPMG continuously works to identify and mitigate healthcare inequities, and that starts with providing an inclusive, supportive environment for our physicians and staff. We encourage applicants of any race, color, religion, sex, sexual orientation, gender identity, or national origin who value diversity and will commit to practicing culturally competent healthcare. External hires must pass a background check and drug screening.
    $152.8k-191k yearly 60d+ ago
  • Research Scientist - CTRL Labs

    Meta 4.8company rating

    Senior scientist job in Washington, DC

    Reality Labs at Meta is seeking Research Scientists with experience in product-focused machine learning and signal processing research to advance our pioneering work in neuromotor interfaces, which has grown out of the acquisition of CTRL-labs. We're building a practical interface drawing on the rich neuromotor signals that can be measured non-invasively via surface electromyography (EMG) with single motor neuron resolution. This technology could become one of the main pillars for interaction with virtual and augmented worlds.We are a multi-disciplinary team of researchers investigating the nature of human neuromotor signals, developing novel signal processing and machine learning methods to infer a user's intent, and creating novel interaction techniques and user experiences. Help us unleash human potential by removing the bottlenecks between user intent and action. **Required Skills:** Research Scientist - CTRL Labs Responsibilities: 1. Research and develop Deep Learning or other computational models 2. Design methods, tools and infrastructure to analyze and leverage rich multimodal data sets 3. Set technical direction for a project of 2-3 researchers and engineers 4. Help transition and deliver our work from research into product 5. Adapt standard machine learning methods to best leverage modern parallel environments (e.g. distributed clusters, multicore SMP, and GPU) **Minimum Qualifications:** Minimum Qualifications: 6. Bachelor's degree in Computer Science, Computer Engineering, relevant technical field, or equivalent practical experience 7. Ph.D. degree in Computer Science and Engineering, Electrical Engineering, Statistics/Mathematics 8. Experience with developing machine learning models at scale from inception to business impact 9. Programming experience in Python and hands-on experience with frameworks such as PyTorch 10. Exposure to architectural patterns of large scale software applications 11. Must obtain work authorization in the country of employment at the time of hire, and maintain ongoing work authorization during employment **Preferred Qualifications:** Preferred Qualifications: 12. Proven track record of achieving significant results as demonstrated by grants, fellowships, patents, as well as first-authored publications at peer-reviewed AI conferences (e.g. NeurIPS, CVPR, ICML, ICLR, ICCV, ACL, and ICASSP) 13. Demonstrated software engineer experience via an internship, work experience, coding competitions, or widely used contributions in open source repositories (e.g. GitHub) 14. Experience bringing machine learning-based products from research to production **Public Compensation:** $184,000/year to $257,000/year + benefits **Industry:** Internet **Equal Opportunity:** Meta is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, transgender status, sexual stereotypes, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. We also consider qualified applicants with criminal histories, consistent with applicable federal, state and local law. Meta participates in the E-Verify program in certain locations, as required by law. Please note that Meta may leverage artificial intelligence and machine learning technologies in connection with applications for employment. Meta is committed to providing reasonable accommodations for candidates with disabilities in our recruiting process. If you need any assistance or accommodations due to a disability, please let us know at accommodations-ext@fb.com.
    $184k-257k yearly 60d+ ago
  • Support Scientist IV

    STC 4.0company rating

    Senior scientist job in Greenbelt, MD

    About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site with global collaborations Travel: Frequent (domestic & international field missions, scientific meetings) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $130K - $175K Job Description: The Support Scientist IV will serve as a senior researcher under the ATMOS contract at NASA GSFC, leading major research efforts in atmospheric science. This includes computational modeling, instrument development, and analysis of large satellite datasets. The role requires collaboration with scientists across institutions and management of junior researchers. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Plan and direct scientific research tasks in atmospheric science. Lead development of computational models and instrumentation concepts. Publish extensively and represent NASA at international conferences. Mentor and oversee other scientists within project teams. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements 10+ years of scientific research experience. 5+ years of leadership in scientific project management. Strong background in atmospheric science with proven publication record. Advanced programming expertise (FORTRAN, C/C++, Python). Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or M.S. degree in one of the listed disciplines, plus ten years of experience relevant to the position. This experience is in addition to the experience required for the position level.
    $130k-175k yearly 60d+ ago
  • Scientist Physician (Traumatic Brain Injury)

    GDIT

    Senior scientist job in Silver Spring, MD

    Type of Requisition: Regular Clearance Level Must Currently Possess: None Clearance Level Must Be Able to Obtain: None Public Trust/Other Required: NACLC (T3) Job Family: Science and Research Job Qualifications: Skills: Brain Injury, Clinical Care, Physical Medicine and Rehabilitation Certifications: None Experience: 5 + years of related experience US Citizenship Required: No Job Description: GDIT's Federal Health/ Military Health team is hiring a TBI Subject Matter Expert (MD, DO, PhD, MD/PhD, OD) to join the Traumatic Brain Injury Center of Excellence (TBICoE) located at HQ in Silver Spring, MD. **Position is full-time, on-site** As the traumatic brain injury (TBI) Pathway of Care manager within the Military Health System (MHS), TBICoE promotes state-of-the-science care from point-of-injury to reintegration for Service members, veterans, and their families to prevent and mitigate consequences of mild to severe TBI. TBICoE unifies a system of TBI health care, reliably advancing the science for the warfighter and ready to meet future brain health challenges. Learn More here --> Traumatic Brain Injury Center of Excellence | Health.mil S/he serves as the SME for TBI across the spectrum of severity . S/he is expected to perform with minimal direction and oversight in her/his areas of expertise and responsibility as part of a high-tempo office environment that is responsive to needs of DHA and DOD leadership, TBI clinicians/providers, brain health educators, and cognitive monitoring programmatic issues. HOW YOU WILL MAKE AN IMPACT Serves as a TBICoE SME for mild, moderate, severe, and penetrating TBI including knowledge from prevention to rehabilitation and stays actively informed on emerging areas of brain health to include blast overpressure, high and low-level blast, cognitive monitoring and performance. Demonstrates knowledge of research on emerging areas of clinical practice, brain health threats, and warfighter-relevant demand signals. Provides expertise and analysis to TBICoE senior leadership on issues of TBI research, clinical care and standards of care for patients along the full continuum of TBI severity. Collaborates with and receives direction from TBICoE leadership, DoD health care policy offices and other SMEs to assist in enhancing metrics for evaluation of and standardization of TBI services and programs. May provide input for development of training platforms/tools. When appropriate, provides direct training. Provides consultation to leadership in TBICoE, DoD and clinical programs regarding the evidence on TBI evaluation, treatment and management, identification of gaps in evidence, the current and future needs in the military and future research requirements. Supports TBICoE researchers in their TBI research as an SME. May directly collaborate in TBICoE/DoD research projects. Attends and participates in scholarly, academic and scientific meetings related to TBI, brain health, blast, or cognitive monitoring. Must adhere to legal, professional and ethical codes with respect to confidentiality and privacy WHAT YOU'LL NEED TO SUCCEED (required): Professional degree (MD, DO, PhD, MD/PhD, OD or relevant terminal doctorate degree) with specialty training in TBI-related field (e.g., physical medicine and rehabilitation science, physical or occupational therapy, cognitive neuroscience, neuro-ophthalmology, neuro-optometry, cognitive behavioral science, neurology, neurosurgery, or a related discipline. 5+ years of experience in healthcare and/or healthcare research required. Published in peer review publications and/or presentations at professional meetings. Excellent oral and written communications required. Knowledge of TBI and statistics, required. Must have strong collaborative and organizational skills. Must be able to pass a favorable T3 security investigation. WHAT WOULD BE EVEN BETTER (preferred): Prior experience or knowledge of DoD and VA health care systems strongly preferred. Current or prior board certification in field of expertise may be granted preference. GDIT IS YOUR PLACE: Full-flex work week to own your priorities at work and at home 401K with company match Comprehensive health and wellness packages Internal mobility team dedicated to helping you own your career Professional growth opportunities including paid education and certifications Cutting-edge technology you can learn from Rest and recharge with paid vacation and holidays #GDITFedHealthJobs #GDITHealth #MilitaryHealthGDITJobs #GDITpriority The likely salary range for this position is $128,039 - $173,229. This is not, however, a guarantee of compensation or salary. Rather, salary will be set based on experience, geographic location and possibly contractual requirements and could fall outside of this range. Scheduled Weekly Hours: 40 Travel Required: None Telecommuting Options: Onsite Work Location: USA MD Silver Spring Additional Work Locations: Total Rewards at GDIT: Our benefits package for all US-based employees includes a variety of medical plan options, some with Health Savings Accounts, dental plan options, a vision plan, and a 401(k) plan offering the ability to contribute both pre and post-tax dollars up to the IRS annual limits and receive a company match. To encourage work/life balance, GDIT offers employees full flex work weeks where possible and a variety of paid time off plans, including vacation, sick and personal time, holidays, paid parental, military, bereavement and jury duty leave. To ensure our employees are able to protect their income, other offerings such as short and long-term disability benefits, life, accidental death and dismemberment, personal accident, critical illness and business travel and accident insurance are provided or available. We regularly review our Total Rewards package to ensure our offerings are competitive and reflect what our employees have told us they value most.We are GDIT. A global technology and professional services company that delivers consulting, technology and mission services to every major agency across the U.S. government, defense and intelligence community. Our 30,000 experts extract the power of technology to create immediate value and deliver solutions at the edge of innovation. We operate across 50 countries worldwide, offering leading capabilities in digital modernization, AI/ML, Cloud, Cyber and application development. Together with our clients, we strive to create a safer, smarter world by harnessing the power of deep expertise and advanced technology.Join our Talent Community to stay up to date on our career opportunities and events at gdit.com/tc. Equal Opportunity Employer / Individuals with Disabilities / Protected Veterans
    $128k-173.2k yearly Auto-Apply 6d ago
  • Scientist 2 - Product Characterization

    Merck KGaA

    Senior scientist job in Rockville, MD

    Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: At MilliporeSigma, as a Scientist 2 - Analytical Development, you will be the primary scientific resource for a given study with the Product Characterization Laboratory in our Biologics department. The Scientist will act as subject matter expert in analytical method development/validation and feasibility/transfer for testing required to manufacture clinical and commercial products. * Understand GMP requirements for validation/transfer and documentation * Act as subject matter expert (SME) in analytical methods and provide guidance to analysts and study managers. * Apply laboratory techniques and skills to complete experiments designed to address a variety of specific problems. * Lead development/validation and feasibility/transfer of analytical methods and ensure timely initiation and completion of studies. * Prepare/ review protocols, reports, SOPs, laboratory records, tech specifications, and other related documents. * Execute analytical methods in the lab for assay development/validation, feasibility/transfer. * Perform testing in accordance with SOPs and regulations (cGMP) * Transfer GMP assays to the routine team and provide training to the analysts, study managers, report writers and QA. * Operates, maintains lab equipment as required by SOPs and testing procedures. * Utilize applicable computer programs during testing and routine tasks (i.e. Word, Excel, Oracle, LIMS, BRIQS, etc) * Lead general change control and resolve deviations by completing event records * Contribute ideas and suggestions to improve standard laboratory techniques, protocols, processes, and equipment * Ensure current regulatory requirements and technical needs of internal and external clients are appropriately met. * Maintain strong communication skills to effectively interact with internally and externally stakeholders. * Engage directly with clients. * Performs other duties as assigned. Who You Are Minimum Qualifications: * Ph.D. in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 3+ years relevant experience -OR- * Master's Degree in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 5+ years relevant experience -OR- * Bachelor's Degree in a scientific discipline (e.g., Analytical Chemistry, Chemistry, Biology, etc.), with 7+ years industry experience Preferred Qualifications: * Experience with some or all of the following technical disciplines: * Liquid Chromatography (SEC, RP, IEX, etc.), * Mass Spectrometry (Intact Molecular weight, Peptide mapping, Disulfide mapping, Glycan Profiling, N-/C-Terminal Sequencing) * Capillary Electrophoresis Methods (CE-SDS, cIEF) * Compendial assays, etc. * Broad working knowledge of filed and experience with relevant laboratory practices, techniques, equipment, materials and mathematical calculations. * Intermediate skills in applicable computer programs. * Experience of method development in a pharmaceutical laboratory or similar field. * Excellent verbal and written communication skills that have been demonstrated through presentations/seminars, oversight of projects, implementation of new services, etc. * Excellent time management skills. * Demonstrates a high level of initiative and leadership capabilities. * Effective coaching and training skills for complex and highly technical work. Pay Range for this position - $75,400 - $131,400 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
    $75.4k-131.4k yearly 18d ago
  • Research Scientist - EM Modelling & Simulation

    Intelligent Automation, Inc. 4.2company rating

    Senior scientist job in Rockville, MD

    Intelligent Automation, Inc. (IAI) is seeking highly motivated Research Scientists with experience in electromagnetic theory and simulations, electromagnetic propagation modeling and ray tracing. Job duties include research and software development for modeling and simulation of advanced wireless propagation, ray tracing, radiative transfer, and physical/geometric optics algorithms. U.S. citizenship or green card is required for this job. Required Skills • M.S. or Ph.D. in Electrical Engineering (or a related field). • Experience in electromagnetic theory and computation electromagnetics. • Experience in software development and implementation of algorithms in MATLAB, C/C++, and Java. • Solid background in EM theory and simulations, including physical/geometric optics, ray tracing, diffraction. • Strong analytical, verbal and written communication skills. • Experience in authoring technical publications and grant proposals. Any experience with supporting software architecture and product development, generating system requirements and design documents, and software testing is a plus. ABOUT IAI Intelligent Automation, Inc. (IAI) is a technology innovation company headquartered in Rockville, MD. For over 30 years, we have specialized in providing advanced technology solutions and R&D services to federal agencies and corporations throughout the United States and internationally. Leveraging agile R&D processes, a multi-disciplinary collaborative environment, and its substantial intellectual property portfolio, IAI excels in developing concepts into market-focused products and customer-driven solutions. IAI's core R&D areas include: Air Traffic Management, Big Data and Social Media Analytics, Control and Signal Processing, Cyber Security, Education and Training Technologies, Health Technologies, Modeling and Simulation, Networks and Communications, Robotics, and Sensor Systems. US Citizenship or Permanent Residency required All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status. Research Scientist - Electromagnetic Modeling and Simulation (M&S)
    $73k-107k yearly est. Auto-Apply 60d+ ago
  • Staff Scientist Assay Development, Quality, and Manufacturing Support

    Novel Microdevices Inc.

    Senior scientist job in Baltimore, MD

    Job DescriptionSalary: Staff Scientist Assay Development, Quality, and Manufacturing Support Department: R&D / Quality / Manufacturing Reports To: VP of Assay Development and Chief Operating Officer The Scientist will play a key role in supporting the development, validation, and manufacturing of Novel Microdevices molecular diagnostic assays and reagents. This cross-functional position bridges R&D, Quality Control, and Manufacturing, ensuring that new assays and production lots meet performance, consistency, and regulatory requirements. The ideal candidate is a hands-on scientist who enjoys both bench-level experimentation and structured quality processes, thrives in a fast-paced startup environment, and contributes to the continuous improvement and commercialization of diagnostic products. Key Responsibilities Assay Development & Verification Support R&D in the design, optimization, and verification of new molecular diagnostic assays (e.g., qPCR, nucleic acid extraction, reagent formulation). Conduct feasibility, design transfer, and V&V (Verification & Validation) testing to ensure product performance and regulatory compliance. Perform analytical testing to assess assay sensitivity, specificity, reproducibility, and robustness. Analyze, interpret, and present experimental data to cross-functional teams. Reagent & Manufacturing Support Collaborate with Manufacturing to scale reagent formulations, optimize processes, and ensure lot-to-lot consistency. Conduct in-process, release, and stability testing on raw materials, intermediates, and finished products. Develop and refine SOPs, batch records, and test methods for reagent preparation and product release. Support troubleshooting of reagent production issues and contribute to process improvements. Execute and document QC methods in compliance with ISO 13485, FDA 21 CFR Part 820, and IVDR standards. Support method validation, transfer, and verification in alignment with CLSI and internal quality requirements. Participate in investigations of nonconformances, OOS/OOT events, and CAPA development. Ensure accurate and complete documentation consistent with design control, traceability, and QMS standards. Cross-Functional Collaboration Work closely with QA, R&D, and Operations to support technology transfer and readiness for scale-up. Provide technical input for product characterization, design reviews, and risk assessments (ISO 14971). Train and mentor laboratory staff on analytical methods, data integrity, and best practices. Contribute to continuous improvement initiatives to strengthen product performance and operational efficiency. Minimum Qualifications PhD or Masters degree in Molecular Biology, Biochemistry, Biotechnology, or a related life science field, or equivalent experience in assay development or molecular diagnostics; with at least 2 years of relevant experience; OR Bachelors degree in a related discipline with at least 5 years of relevant experience in assay development, molecular biology, or quality control within a regulated IVD or life sciences environment. Hands-on experience with qPCR and molecular assay techniques, including nucleic acid extraction, amplification, or detection. Working knowledge of ISO 13485, FDA 21 CFR Part 820, or similar quality management systems. Strong experimental design, troubleshooting, and data analysis skills. Excellent documentation, organization, and communication skills with a proven ability to collaborate across R&D, Manufacturing, and QA/QC. Preferred Qualifications Experience in IVD assay development and design transfer from prototype to production. Familiarity with reagent formulation, lyophilization, or stability studies. Prior involvement in V&V studies, design control documentation, or regulatory submissions. Knowledge of statistical tools for data trending and method validation (e.g., JMP, Minitab, or equivalent). Exposure to risk management (ISO 14971) and document control systems.
    $81k-124k yearly est. 28d ago
  • Applied AI Health Scientist (ARPA-H)

    Ripple Effect 3.9company rating

    Senior scientist job in Washington, DC

    Job Description General Information Job Code: SHR-BI-05T Employee Type: Exempt, Full-Time Regular Telework: Ad hoc as determined by client Salary Range: $129,985.76 - $149,483.62 per year (how we pay and promote) Citizenship: U.S. Citizen as required by client Position Overview Are you passionate about managing information to drive innovation and impact? As a Applied AI Health Scientist supporting our client, you will play a pivotal role in shaping our success. This is a Science and Engineering and Technical Advisor (SETA) role in the Proactive Health Mission Office at the Advanced Research Projects Agency for Health (ARPA-H) responsible for providing expertise in artificial intelligence and machine learning to support a program advancing AI diagnostics for rare diseases. Successful candidates have the ability to critically assess technical approaches, advise program leadership, and ensure that funded performers and partners are meeting the highest standards of rigor, reproducibility, and real-world applicability. You will contribute expertise across the full lifecycle of AI system development: data aggregation and curation, model training and benchmarking, and deployment/validation in real-world clinical settings. Primary Responsibilities While not an exhaustive list, the key duties for the position include: Review and evaluate AI/ML technical proposals and deliverables from external teams. Provide guidance on model development, training methods, and validation strategies. Advise on integration of multimodal health data (EHR, imaging, genomic, and patient-reported). Assess alignment of model architectures and approaches with program goals and clinical use cases. Evaluate benchmarking results and provide feedback on methodological soundness. Advise on deployment considerations, including interpretability, reliability, and safety in real-world settings. Collaborate with clinical SMEs to ensure AI outputs align with clinician expectations and workflows. Identify risks, gaps, or weaknesses in technical approaches and recommend corrective actions. Support program leadership with technical assessments, reports, and recommendations. Produce high-quality written reports and presentations that synthesize complex technical findings for diverse audiences. Requirements Minimum Education and Experience: Master's degree in Computer Science, Machine Learning, Data Science, or related field. 10+ years of relevant professional experience. Basic Requirements: Experience applying advanced ML methods (LLMs, deep learning, etc) to complex health datasets. Familiarity with clinical and biomedical data types, including EHR, genomic, and imaging data. Demonstrated ability to review, critique, and guide AI/ML technical work at a high level. Strong understanding of evaluation methods for AI/ML, including robustness, fairness, interpretability, and reproducibility. Strong written and visual communication skills, with ability to produce high-quality reports and presentations. Intermediate experience with Microsoft Office productivity software and collaboration tools such as Microsoft Teams and SharePoint. Skills That Set You Apart: Experience in healthcare AI or biomedical applications. Familiarity with the rare disease field Prior involvement in technical advisory, evaluation, or SETA-style roles. Experience working with interdisciplinary teams including clinicians and patient stakeholders. Experience working in an early-stage, fast-paced, startup environment About Ripple Effect Ripple Effect is an award-winning women-owned, 200-person company of communicators, scientists, researchers, and analysts. Established in 2003, and named as one of the “Best and Brightest Companies to Work For” since 2020, Ripple Effect has earned acclaim for delivering unparalleled consulting services and top-tier talent across federal, private, and non-profit sectors. Benefits At Ripple Effect, we reward our employees for their contributions to our mission. Our comprehensive total rewards package includes competitive pay, exceptional benefits, and a range of programs that support your work/life balance and personalized preferences. Learn more about our benefits and culture here.
    $130k-149.5k yearly 11d ago
  • Machine Learning Scientist

    Systems Integration 4.3company rating

    Senior scientist job in Washington, DC

    Data Scientist Systems Integration, Inc. (SII) is a leading provider of customer experience, data analytics and digital transformation solutions . We are seeking a highly skilled Machine Learning Scientist to help the FBI uncover actionable insights from vast and complex data sets. This role focuses on identifying enterprise-level toolsets, applying advanced data mining techniques, and building predictive models that integrate with FBI systems. The ideal candidate will be a strategic thinker with deep technical expertise and the ability to communicate findings clearly across all levels of the organization. Responsibilities: Select, build, and optimize machine learning classifiers using advanced techniques Apply state-of-the-art data mining methods to extract meaningful patterns Enhance data collection procedures to ensure relevance for analytic systems Cleanse, process, and validate data integrity for analysis Conduct ad-hoc analyses and present results in a clear, actionable format Develop and monitor automated anomaly detection systems Design innovative approaches for handling and analyzing large-scale data sets Address fundamental challenges in data handling, search, and retention Solve complex data storage and retrieval issues Develop software solutions to improve data search and access processes Analyze results and deliver recommendations that support mission objectives. Qualifications: Must be US Citizen Requires a Top-Secret clearance (SCI Poly may be required later). Strong understanding of machine learning algorithms (e.g., kNN, Naive Bayes, SVM, Decision Forests) Proficiency with data science toolkits such as R, Weka, NumPy, and MATLAB Excellent communication and presentation skills Experience with tools like Microsoft Power BI, Anaconda, and SPSS Skilled in data visualization using D3.js, GGplot, or similar platforms Proficient in SQL and Hive for querying large datasets Experience with NoSQL databases (e.g., MongoDB, Cassandra, HBase) Solid foundation in applied statistics (distributions, testing, regression) Strong scripting and programming capabilities. Minimum 5 years of experience supporting data-driven projects of similar scope. Bachelor's degree required in data science, statistics, computer science or related field.
    $66k-97k yearly est. 60d+ ago
  • Scientist

    Camris 4.6company rating

    Senior scientist job in Bethesda, MD

    We are seeking a Scientist to support the National Institutes of Health's (NIH), world renowned National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, MD. Our NIAID professional, technical, and scientific support personnel are part of a preeminent team focused on positively impacting millions of lives around the world with groundbreaking research. Candidates will work at a prominent and vibrant NIAID worksite to directly support exciting ongoing research activities as a contractor team member. Accelerate your career and apply below to help us make a difference. CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs. Our employees enjoy a collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad. Responsibilities Plan and execute a wide range of complex procedures and techniques including, aseptic cell culture, molecular biology (DNA/RNA isolation, cloning, analysis, purification, Illumina next generation sequencing, RNAseq through single cell SMARTseq, 10X Genomics), and cellular assays (binding and neutralization). Design and implement improved methods to existing single-cell sequencing protocols. Develop and optimize assays for diverse new projects. Conduct research including planning and conducting experiments and data analysis. Maintain and operate a variety of laboratory instruments. Collaborate with scientists from other organizations or institutions involved in similar or related research projects. Provide support and mentor to students, post-doctoral fellows and non-doctoral research technicians on experimental design and laboratory-based methodologies. Maintain accurate daily records of experiments to include the organization and archiving of research data properly. Manage project pipeline for the Vaccine Immunology Program. Maintain, operate, and optimize robotics to increase library prep throughput and sample clean-up. Integrate single cell next generation sequencing instruments (NextSeq, Miseq, 10x Chromium) to increase the project versatility of the Genome Analysis Core. Produce high quality scientific data and analysis consistently using new methods such as single cell sequencing. Analyze and interpret research data, communicate results and methods in reports, presentations, and manuscripts. Prepare presentations of research for internal data review and for external audiences. Help train post-baccalaureate IRTAs in molecular biology assays in the core. Train collaborators in molecular biology assays performed by the core. Wear appropriate Personal Protective Equipment (PPE) in a BSL-2 laboratory. Work collaboratively with team members to complete all tasks for the day but also be accountable as an individual for personal tasks. Utilize various laboratory equipment such as Biological Safety Cabinet (BSC), centrifuge, pipettes, liquid nitrogen tank, and others. Perform basic equipment maintenance as needed. Write and revise SOPs within VIP's electronic database. Performs other duties as assigned. Qualifications Master's degree in Biology, Life Sciences, or a related discipline. Two (2) years of specialized experience plus a BA/BS degree is equivalent to a Master's degree. Minimum of five (5) years of experience in biology or a related field including cell and molecular biology, immunology, and/or next generation sequencing. Experience with complex procedures and techniques including but not limited to aseptic cell culture, molecular biology, and cellular assays: Specifically with DNA/RNA isolation, cloning, purification, Illunina net generation sequencing, RNAseq through single cell SMARTseq, and 10X Genomics. Experience maintaining and operating a variety of laboratory instruments. Strong communication skills. Ability to work well with others and independently. Physical Requirements: The physical requirements described here are representative of those that must be met by a candidate to perform the essential functions of this job. Reasonable accommodations may be provided to enable individuals with disabilities to perform essential job functions. Ability to lift or carry less than 25 pounds, lift or carry 25 - 50 pounds, push or pull less than 25 pounds, push or pull 25 - 45 pounds, reach above shoulder level, and use both hands. Will be required to stand or walk more than 25 of 30 min. Must have depth perception, ability to distinguish basic colors, and perform repetitive activities. Ability to work alone and closely with others, work on shifts, and work with solvents. Will be required to be in contact with human blood or other body fluids. Will have contact with HIV-1, HIV-2, MMR viruses, and Varicella virus. Will work with aerosols, biological inhalants, corrosive substances, plastics, and solvents. Must be able to wear personal protective equipment (PPE), including gloves, face shields/goggles, safety glasses, lab coat, and disposable dust/surgical mask. Please submit your resume online at ************** . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law. CAMRIS offers a comprehensive benefits package, including medical, dental, and vision insurance for individuals and families, FSAs, HSA, life and AD&D insurance, short- and long-term disability, legal services, voluntary hospital indemnity, critical illness and accident insurances, EAP, pet insurance, 401(k) with employer match and Roth option, tuition and professional reimbursement, public transportation support in the DMV area, a referral bonus program, vacation with tenure-based increases, PTO, 11 paid holidays, paid bonding leave, and paid supplemental short-term disability. Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.
    $77k-114k yearly est. Auto-Apply 6d ago
  • Scientist, Discovery

    Arcellx 4.0company rating

    Senior scientist job in Rockville, MD

    Who We Are Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible. Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work. What Matters to Us Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team. Arcellx Core Values Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work. Think ‘we' before ‘me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals. Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right. How You'll Make a Difference As a Scientist , your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients. The “Fine Print” - What You'll Do Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies. Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed. Develop new methods, technologies and processes when necessary for project. Exercise significant technical discretion in the design, execution and interpretation of experiments. Communicate progress and project recommendations to team members. Skills and Experience We Look For BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience. Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis. Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation). Preference for experience in drug development, immunology or protein engineering. The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams. Rewards at Arcellx Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits. The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required. Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to **************** #LI-Onsite
    $100k-120k yearly Auto-Apply 60d+ ago
  • Research Scientist

    Howard University 4.4company rating

    Senior scientist job in Washington, DC

    The Talent Acquisition department hires qualified candidates to fill positions which contribute to the overall strategic success of Howard University. Hiring staff “for fit” makes significant contributions to Howard University's overall mission. At Howard University, we prioritize well-being and professional growth. Here is what we offer: Health & Wellness: Comprehensive medical, dental, and vision insurance, plus mental health support Work-Life Balance: PTO, paid holidays, flexible work arrangements Financial Wellness: Competitive salary, 403(b) with company match Professional Development: Ongoing training, tuition reimbursement, and career advancement paths Additional Perks: Wellness programs, commuter benefits, and a vibrant company culture Join Howard University and thrive with us! *************************************** JOB PURPOSE: Howard University seeks a highly skilled and motivated Biomedical Research Scientist specializing in neuroscience and genomic regulation to join its growing biomedical research enterprise. The incumbent will design and implement independent and collaborative projects focused on neuroscience and molecular/cellular signaling, contributing to Howard University's mission of advancing health equity through cutting-edge biomedical research. SUPERVISORY AUTHORITY: Under the supervision of the Principal Investigator, formally plans, executes the designated project (s) in the laboratory. Typically, responsible for performing non-supervisory duties, but usually participates in the training and supervision of the laboratory work of students. NATURE AND SCOPE: Internal contacts include investigators, administrators, faculty, staff and students both within the department/center and University-wide. External contacts include government agencies, scientific collaborators, vendors, visitors, and the general public. PRINCIPAL ACCOUNTABILITIES: Design and execute experimental studies in molecular and cellular neuroscience, focusing on neuroprotection, neuroinflammation and genomics. Perform advanced rodent stereotaxic surgeries, tissue collection, immunohistochemistry (IHC), confocal microscopy, and image analysis. Conduct molecular and biochemical assays (DNA, RNA, and protein-based techniques) to characterize neuronal and metabolic functions. Utilize and maintain advanced imaging and spatial profiling systems (e.g., confocal, expansion microscopy, nCounter, or GeoMx digital spatial profiling). Analyze, interpret, and present data at internal seminars, conferences, and scientific meetings. Prepare manuscripts, progress reports, and grant proposals in collaboration with principal investigators. Mentor students, fellows, and research trainees in laboratory methods and research ethics. Ensure full compliance with Howard University, NIH, and federal policies on biosafety, animal care, and research integrity Perform other related duties as assigned. CORE COMPETENCIES: Familiarity with digital spatial profiling, multiplex imaging, or bioinformatics analysis. Experience contributing to NIH-funded research projects. Prior supervisory or mentoring experience in academic or laboratory settings Advanced technical expertise in neuroscience and metabolism research. Strong analytical and problem-solving abilities. Attention to detail and accuracy in data management. Commitment to promoting diversity, equity, inclusion, and ethical research practices. MINIMUM REQUIREMENTS: Doctoral degree (Ph.D., M.D., D.V.M., or equivalent) in Neuroscience, Biochemistry, Physiology, Molecular Biology, or a related biomedical field. At least 5 years of postdoctoral or equivalent research experience in neuroscience, molecular biology, or related biomedical research areas. Demonstrated proficiency with rodent models, stereotaxic surgery, microscopy, and molecular biology techniques. Evidence of a strong publication record in high-impact journals. Excellent written and oral communication skills. Demonstrated ability to work independently and collaboratively in a multidisciplinary research environment. Compliance Salary Range Disclosure $80,000-$90,000
    $80k-90k yearly Auto-Apply 55d ago
  • Scientist (Cell Culture)

    Hunterian Medicine 3.3company rating

    Senior scientist job in Baltimore, MD

    We are seeking a highly motivated individual to join our R&D team to develop novel therapeutics using CRISPR and gene therapies. We are looking for a Cell Culture Scientist who will be responsible for maintaining cell cultures and carrying out in vitro studies. Candidates should have extensive experience in mammalian cell culture, ideally with previous stem cell culturing and/or cell engineering expertise. Other responsibilities include general upkeep and maintenance of cell culture supplies and equipment. The successful candidate will have the opportunity to work collaboratively in a small team using cutting-edge techniques to treat diseases. We are seeking a team player who can learn quickly and carry out assignments independently. An ideal candidate is expected to display a high level of passion and curiosity, with a strong sense of urgency to develop important new therapeutics for devastating genetic diseases. Required Skills and Qualifications 3+ years of mammalian cell culture. Advanced degree is a plus. Previous experience with functional cellular assays. Stem cell culturing and/or cell engineering experience is a plus. Python, R, or any programming experience. Good oral and written communication skills is required. What We Offer Hunterian Medicine offers a dynamic start-up environment and a collaborative, passionate team. Competitive salary and compensation. Paid vacation and sick time. Medical insurance, retirement plan and other employee benefits. Company Overview Hunterian Medicine is a pre-clinical gene-editing and gene therapy company working to cure genetic diseases. Areas of in vivo development focus include CNS, ophthalmology, neuromuscular, and pulmonary, among others. For more information, please visit ****************** Located in Cambridge, Massachusetts, and Baltimore, Maryland, Hunterian Medicine LLC is an equal opportunity employer. We consider applicants for employment, and make employment decisions, without unlawful regard to sex, race, color, religion, national origin, sexual orientation, age, disability, marital or domestic partner/civil union status, or veteran status, and any other characteristic covered by applicable federal, state or local nondiscrimination laws.
    $71k-105k yearly est. Auto-Apply 60d+ ago
  • Scientist

    Vandstrom

    Senior scientist job in Gaithersburg, MD

    Vandstrom is seeking a scientist with expertise in integral membrane proteins. Please refer to the attached job description for the details.
    $69k-101k yearly est. Auto-Apply 60d+ ago
  • Senior/Junior BI Scientist

    Psomagen Inc.

    Senior scientist job in Rockville, MD

    Job Description Senior/Junior Bioinformatics Scientist About Psomagen Psomagen Inc. is a rapidly growing biotechnology company renowned for providing a variety of genomics-based molecular assay solutions to research and clinical communities. We are looking to expand our bioinformatic analysis capabilities to broaden our service area into Multi-Omics solutions. We are searching for a highly motivated Senior Manager in Bioinformatic analysis with extensive experience in NGS based bioinformatic analysis. Position Overview Are you seeking an opportunity where you can lead the technological advancement of precision medicine in a well-established research environment? Do you want to use your knowledge and experience to lead the expansion of a rapidly growing biotechnology company? If you are eager to pursue a challenge in developing new biotechnological assays with well-motivated colleagues, join our bioinformatics team! The ideal candidate will take ownership of the development, execution, and improvement of analysis pipelines for Next-Generation Sequencing (NGS) services. The individual may also execute collaborative projects with external researchers and join the customer facing discussion. This role will contribute to growing, coaching, and aligning the team towards the shared vision of delivering high quality data analysis for our customers. This role is an on-site position in Rockville, MD Key Responsibilities ● Generate analytical pipelines and perform data analysis using the Illumina Dragen suite. ● Perform bioinformatic analyses on NGS data, ensuring accuracy and reliability of the dataset and conduct quality control assessments of NGS data, adhering to industry standards and company protocols ● Develop and maintain reproducible NGS data analysis pipelines in the AWS environment, ensuring the reliability and scalability of workflows. ● Develop HTML-based data analysis reports for customers, summarizing and visualizing raw and analyzed datasets. ● Supervise bioinformatics team members, including task delegation, performance evaluation, and continuous professional development of junior team members. ● Support research projects, including managing large amounts of data, monitoring, and running the developed pipelines. ● Generate the documentation related to the pipelines (Reports, README, etc). ● Stay abreast of current developments in public bioinformatics tools, pipelines and databases. ● Participation in customer-facing discussions with field application scientists to support business development/customer services activities. ● Planning and writing various ad-hoc scripts and visualization scripts to analyze specific data and interpret results. ● Demonstrate good judgment in selecting methods and techniques for obtaining solutions while resolving a wide range of issues in creative ways. ● Research independently within a team environment to develop and improve genomics analysis solutions. Qualifications ● Junior Level: Bachelor's or Master's degree in Biology, Bioinformatics, Computer Science, or a related field with 1-3 years of relevant experience. ● Senior Level: Master's degree with 3+ years of industry experience OR a Ph.D. in Bioinformatics, Computer Science, Biology, Genetics, or a similar field. ● Strong knowledge and proficiency in Bash, R, Python, and other relevant programming languages for bioinformatics pipeline development. ● Proficiency in NextFlow is highly preferred and other workflow languages are a plus. ● Experience operating the Illumina DRAGEN package from command line or web-based UI is a plus. ● Advanced experience working with Linux environments and familiarity with HPC systems for large-scale NGS data analysis. ● Experience using bioinformatics tools and familiarity with genomics databases. ● Good communication, interpersonal and presentation skills for team work. ● Ability to work as part of a team and with external collaborators. ● Ability to independently and reliably complete tasks and projects. ● Detail oriented and team-oriented leadership What We Offer ● Competitive base salary with a performance-based commission structure. ● Comprehensive medical, dental, and vision insurance. ● 401(k) retirement plan with company match. ● Generous paid time off (PTO) and holidays. ● Opportunity to lead a pioneering business unit within a rapidly growing company. ● Target Salary Range: $47,000 - $100,000. Salary is determined within this range based on the qualifications.
    $47k-100k yearly 14d ago
  • Flow Cytometry Scientist

    Cs&S Staffing Solutions

    Senior scientist job in Rockville, MD

    Please, review and apply for this position through the QCI system following the link below (Copy and Paste): http://jobs.qcitech.com/jobseeker/Flow_Cytometry_Scientist_J02098387.aspx *You can apply through Indeed using mobile devices with this link. Additional Information
    $69k-101k yearly est. 1d ago
  • Flow Cytometry Scientist

    CS&S Staffing Solutions

    Senior scientist job in Rockville, MD

    Please, review and apply for this position through the QCI system following the link below (Copy and Paste): http://jobs.qcitech.com/jobseeker/Flow_Cytometry_Scientist_J02098387.aspx *You can apply through Indeed using mobile devices with this link. Additional Information
    $69k-101k yearly est. 60d+ ago

Learn more about senior scientist jobs

How much does a senior scientist earn in Baltimore, MD?

The average senior scientist in Baltimore, MD earns between $74,000 and $146,000 annually. This compares to the national average senior scientist range of $74,000 to $153,000.

Average senior scientist salary in Baltimore, MD

$104,000
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