Senior scientist jobs in Manchester, NH - 659 jobs

Applied Physical Sciences (APS) is looking for a highly motivated Physical Scientist to join the Concord, MA team in a part-time, on-call (PTOC) position. Successful candidates will have a PhD in theoretical physics, expertise in inverse theory or tomography, and will support the development of state-of-the-art technologies for tomographic imaging with irregular experiment apertures, with a special emphasis on exploitation of high energy X-rays. APS works on exciting, technically challenging, cutting-edge technologies that will expose candidates to a wide variety of multidisciplinary fields, providing a stimulating environment with considerable opportunity for collegial interaction. At APS you will work in a small company environment where technical excellence is rewarded and an entrepreneurial spirit is encouraged, and you will have the chance to work directly with colleagues and customers that value innovation and creativity. Responsibilities Theoretical modeling of x-ray interaction physics, development of X-ray inversion paradigms for highly challenging experiment scenarios, rigorous characterization of the fundamental information limits of X-ray imaging. Software implementation of processing and modeling techniques, numerical execution of synthetic inversion experiments, display and quantification of model uncertainty Required Attributes and Skills PhD in theoretical physics, and expertise in modeling and inversion of X-ray data Subject matter expertise in one or more of the following: advanced numerical optimization, statistical methods, experiment design optimization, GPU-based computing Extensive experience with computational methods and programming for modeling physical phenomena and processing of real data e.g., Matlab, Python, PyTorch, or Fortran Exceptional communication skills (written and oral) for technical documentation and reviews with customers Desired Attributes and Skills Professional experience of 10+ years in DoD or related industry, a strong publication history in refereed technical journals, and a track record of successful performance on research programs under DARPA, IARPA, NAVSEA or ONR sponsorship is preferred. Experience as principal investigator working on advanced R&D programs Demonstrated technical leadership in modeling and simulation Expertise in one or more of the following: mathematical physics, model-based iterative methods for x-ray tomography, Monte Carlo radiative transport methods for Bremsstrahlung modeling, advanced numerical optimization techniques involving both continuous and discrete variables, regularization methods, uncertainty quantification using the Fisher Information Matrix and the Cramer-Rao Bound, and multi-objective optimization. Experience presenting talks at technical conferences APS, a wholly owned subsidiary of the General Dynamics Corporation, offers a small company environment including competitive salary, excellent benefits, and comfortable working conditions. This is a part-time on-call position open in the Concord, MA office. Candidates must possess or be able to obtain a Top Secret DOD security clearance. Qualified applicants are invited to submit a resume and application online at **************** fax them to ************, Attn: Human Resources, or mail to the company address. Please reference the requisition number and title of the position in the subject line of your submission. Equal Opportunity Employer/M/F/Disability/Protected Vet Invitation to Self-Identify In keeping with our commitment to Equal Employment Opportunity (EEO), Applied Physical Sciences invites all applicants to self-identify pre-offer as a protected veteran and/or an individual with a disability. Invitation to Self-Identify as Protected Veteran Online Form Invitation to Voluntary Self-Identification of Disability Online Form #J-18808-Ljbffr

About the job: SciPro is partnered with a fast growing Scientific Data and AI platform startup who is searching for a Senior Applied AI/ML Engineer to join their team. They are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data across the scientific value chain and scientific vertices. They bring this AI data to life in a fast growing suite of universal lab data management solutions, scientific use cases, and AI-based scientific outcomes. Requirements: You will be a critical team member in a unique partnership to industrialize Scientific AI. As such, you will engage directly with customers onsite up to 4-5 days per week in the Boston region. Advanced degree in Biological, Data, or Computer Science Portfolio demonstrating end-to-end ownership of AI/ML products Proven track record of deploying AI models addressing real world problems Experience in biotech, biopharma, or pharma-adjacent projects Superior talent developing at least one of: ML-Reinforcement Learning, LLM/NLP, or Protein Design/Diffusion Models Responsibilities: Responsible for designing, developing, training, and validation of AI/ML products Support and advise executive leadership regarding technical and commercial feasibility Work with commercial teams to understand the impact of AI in life-sciences Collaborate with cross functional teams to build products Preferred Qualifications: Deep understanding of hurdles facing pharmaceutical drug development Demonstrated ability to make productized applications (for use by more than one group) Excellent communication skills Ability to advocate and evangelize for AI initiatives internally and externally Experience collaborating with teams on large software projects

A leading cancer research institute in Chelsea is seeking a Scientific Officer or Higher Scientific Officer to conduct in vivo experiments aimed at optimizing vaccination approaches for treating cancers with homologous recombination defects. The ideal candidate will hold a current Home Office License, possess expertise in in vivo assays, and contribute to cutting-edge cancer research. This role offers a competitive salary, a supportive research environment, and opportunities for professional development. #J-18808-Ljbffr

+++ SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker. We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing. +++ The Opportunity +++ We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today. This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels. +++ What You'll Do +++ Core Assay Development Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform. Design, execute, and interpret experiments focused on: Binding kinetics & equilibrium optimization Surface functionalization strategies Competitive assay dynamic-range shaping Calibrator and control development (matrix selection, commutability) Assay precision, stability, robustness Analytical Performance & Validation Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17). Establish and demonstrate performance for: Analytical sensitivity & functional limit (LoB/LoD/LoQ) Linearity & reportable range (including hook effects, competitive assay inflection characterization) Repeatability, reproducibility, and nested CV analysis Interference and cross-reactivity studies Matrix equivalency & recovery studies Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks). Cross-Functional Integration Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance. Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing. Documentation & Execution Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations. Present results across the company to inform design decisions and product milestones. +++ What We're Looking For +++ Technical Background PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields. Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus. Demonstrated ability to independently solve complex analytical and biochemical problems. Hands-on experience with complex analytical workflows, assay automation, and instrumentation. Strong understanding of calibration design, commutability, and control strategies. Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks. Regulatory & Platform Experience (Bonus) Experience with IVD development, ISO 13485, or 21 CFR 820. Experience with POC or novel-platform assay development. Knowledge of label-free sensors, waveguides, or photonic resonance systems. Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation. Personal Traits Strong scientific intuition paired with rigorous data discipline. Thrives in a fast-paced, milestone-driven startup environment. Creative problem solver willing to challenge established assay paradigms. High integrity, willingness to own outcomes, and a collaborative mindset. +++ Why This Role Is Unique +++ Most assay developers spend their careers optimizing assays on platforms that already exist. At SiPhox, you will: Build the first generation of photonic immunoassays deployed in consumer health. Design assays whose constraints are shaped by semiconductor physics as much as biochemistry. Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins. See your work ship in a product used at home by real people, not just research labs. If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Expedition Medicines Inc., is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! THE ROLE The Formulation team is seeking a highly motivated, attentive and self-driven candidate to join our team and contribute to the development of discovery compounds as an Senior Research Associate/Associate Scientist. This successful candidate will join an energizing and collaborative research environment working as part of cross function drug discovery teams in providing a develop-ability assessment of innovative molecules. KEY RESPONSIBILITIES Execute stage appropriate, fit-for-purpose preclinical formulations preparation (Solutions, suspensions, emulsions, nanoparticles, SEDDS etc.) for oral, and parenteral formulations on a small scale for small molecules Author protocols describing preparation of formulations for use at internal and external formulation labs Basic drug substance characterization by using techniques such as HPLC/UPLC, XRPD, DSC and PLM. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability Routine lab support such as buffer and mobile phase preparation, pH meter calibration, basic troubleshooting of lab equipment, and coordinating with external instrument and service vendors. Shipping and receiving samples between internal and external sites Summarize experimental results and presents at team meetings and department presentations Author templated memos and reports with limited guidance Maintain detailed lab notebooks and reports in compliance with GLP/GMP guidelines (as applicable) Evaluate novel drug delivery systems (e.g., lipid-based, amorphous solid dispersions, spray dry etc.) for poorly soluble compounds Support transition of formulations from discovery to clinical development (e.g., bridging studies) Independently design and perform focused experiments that drive progress in cross-functional formulation initiatives PROFESSIONAL EXPERIENCE & QUALIFICATIONS B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline is required Three years minimum of industry, government or equivalent experience in small molecules formulation or a related field Hands-on experience with one or more of the following techniques: HPLC, UV-visible, DSC etc Experience with data analysis using standard software platforms (Excel, Prism etc.) Practical experience in developing and preparing preclinical formulations (small molecules) Basic knowledge of physicochemical properties and their relationship to formulation development Basic knowledge of pharmacokinetics (PK) and biopharmaceutics principles The ability to manage multiple parallel activities and deliver results to agreed timelines Ability to do bench work independently Strong collaboration, problem-solving, and adaptability in fast-paced research environments Excellent written, oral, and visual communication skills Excellent time management skills LOCATION: Cambridge, MA ABOUT FLAGSHIP PIONEERING Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-MB1 The salary range for this role is $81,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicine's good faith estimate as of the date of publication and may be modified in the future.

The Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN. Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of “Mentorship-By-Apprenticeship” in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team! The Team The Alloy Genetic Medicines group is innovating a novel RNA-based drug discovery platform, namely “AntiClastic”, spanning the fields of antisense therapeutics to immunomodulating therapeutics. This technology platform was launched by Alloy in 2023 after exclusively licensing its underlying intellectual property which implements a novel spatial conformation of the oligonucleotide developed by Sudhir Agrawal of Arnay Sciences. The team works closely with external partners to discover and develop AntiClastic RNA medicines. The Role This position reports to the Head of Nucleic Acid Chemistry. We are seeking a detail-oriented Nucleic Acid Chemistry Scientist to join our growing Nucleic Acid Chemistry team supporting the CMC development of oligonucleotides, mRNA, pDNA templates, and antibody-oligonucleotide conjugates (AOCs). The successful candidate will bring strong hands-on expertise in synthesis and purification of nucleic acids, as well as HPLC and LC-MS analytics for RNA, DNA, and nucleic acid medicines. You will have a proven track record of developing, documenting, qualifying, and troubleshooting analytical methods and production processes in a fast-paced industrial environment. This role also requires experience working with and managing Contract Research Organizations (CROs), and developing/synthesizing reference materials to enable method development and program progression. This role may be filled at Scientist I or Scientist II depending on experience and demonstrated level of independence. Principal Responsibilities Synthesis and Process Development pDNA Production: Execute microbial fermentation (E. coli) for plasmid DNA amplification; perform harvesting, lysis, and purification of pDNA. Linearization: Perform enzymatic restriction digests to linearize pDNA templates for downstream transcription. mRNA Synthesis: Lead in vitro transcription (IVT) reactions to produce mRNA, including enzymatic capping (Cap 1) and poly-adenylation. Oligonucleotide: Execute procedures to synthesize oligonucleotides. Purification: Utilize TFF (Tangential Flow Filtration) and chromatography (IEX, HIC, or Affinity) to purify intermediates and finished products from process-related impurities. Analytical Method Development & Qualification Develop, optimize, document, qualify, and transfer phase-appropriate analytical methods to support CMC activities for oligonucleotides, mRNA, pDNA, and AOCs. Design fit-for-purpose methods for identity, purity, integrity, potency/assay, and stability, including forced-degradation studies. Lead method qualification/verification activities for nucleic acid CQAs (e.g., product related purity, drug antibody ratios, mRNA capping efficiency, poly-A tail length, and residual template DNA). Execute and interpret analyses using HPLC/UPLC modalities (e.g., IPRP, AE, IEX, HILIC, SEC). Perform and interpret LC-MS analyses for intact oligos, mRNA mapping, sequence confirmation, impurity ID, and conjugate characterization. Independently troubleshoot instrument and method issues, ensuring data integrity and project continuity. Reference Materials Development Develop, qualify, and maintain analytical reference materials (e.g., standards, system suitability controls, impurity markers) to support method development, stability programs, and release testing. Coordinate and/or perform internal synthesis (chemical or enzymatic) of oligonucleotide and mRNA reference materials and related controls. CRO / External Partner Management Work effectively with and manage CRO/CDMO partners executing analytical studies, method development, or mRNA/pDNA manufacturing. Author, review, and approve CRO protocols, reports, data packages, and method documentation. Documentation & Data Integrity Document experiments in real time with excellent attention to detail in electronic lab notebooks. Support regulatory-compliant documentation for IND/BLA/MAA filings and respond to technical inquiries. Qualifications Ph.D. in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2-5 years of industry experience in nucleic acid synthesis or analytical development. Hands-on experience in pDNA, mRNA, and oligonucleotide production: Including microbial fermentation, pDNA purification, linearization, and in vitro transcription (IVT), solid-phase synthesis, & lyophilization. Extensive hands-on experience with HPLC/UPLC and LC-MS applied to mRNA, pDNA, oligonucleotides, and/or oligonucleotide conjugates. Demonstrated success developing and qualifying analytical methods for nucleic acids (e.g., Capillary Electrophoresis/Fragment Analyzer for mRNA integrity). Experience developing, synthesizing/sourcing, characterizing, and maintaining reference materials/standards. Proven experience working with and managing CRO and/or CDMO partners. Strong understanding of nucleic acid challenges (e.g., RNase-free handling, secondary structures, ion-pairing reagents, sequence variants, and conjugation heterogeneity). Experience with antibody-oligonucleotide conjugates (AOCs) and LNP-formulated mRNA. (Preferred) Familiarity with GMP/GLP environments and regulatory expectations for method lifecycle management. (Preferred) Hands-on knowledge of complementary techniques (e.g., qPCR/dd PCR, SEC-MALS, and biophysical assays). (Preferred) Taking Care of Our People We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together , we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one. Compensation Competitive base and equity compensation commensurate with level of experience and independence 401(k) company match Health & Family Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered Company-paid disability (STD, LTD) and life insurance Paid parental leave Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval) Unique Perks Unlimited PTO (paid time off) and flexible schedules Annual stipend for continuing education with commitment to your career through individualized professional development plan Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness Pay Transparency At Alloy Therapeutics, we believe in fostering trust and open communication. For this role, the estimated annual base salary range is $126,000 - $144,000 with the final offer based on factors like your experience, skills, and alignment with our needs. Additionally, this role is eligible for equity compensation, reflecting our commitment to shared success as we work together to make better medicines. We are proud to offer competitive compensation and benefits, aiming to support our team's professional and personal well-being. If you have any questions about pay or benefits, we're here to help. Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected] . We will make every effort to respond to your request for disability assistance as soon as possible.

About Us: SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team (AI Research) is seeking an exceptional Machine Learning Scientist to spearhead the development of our Large Language Models (LLM) and advanced AI agents. This role is pivotal in enabling groundbreaking research in machine learning for scientific discovery, particularly in the realm of material science and battery technology. Harness internal expertise and collaborate with external research labs to advance scientific ML. Work will be incorporated directly into our groundbreaking Deep Space multi-agent system for battery technology discovery. This position can be remote. Essential Duties and Responsibilities: Research & Development Lead cutting-edge research in machine learning for scientific discovery, with a focus on (multimodal) Large Language Models and their application (including AI agents) in battery and material discovery. Conduct groundbreaking research on integrating domain-specific data (including literature and internal documents) into LLM training and inference. Investigate the mechanisms through which LLMs approach problem-solving, planning, and solution generation, particularly in the context of basic battery design questions. Model Optimization & Implementation Troubleshoot and optimize the training process of large language models, addressing complexities and challenges related to data quality, model architecture, and computational efficiency. Implement innovative solutions to enhance model performance and scalability. Collaborate closely with a multidisciplinary team to integrate findings into practical AI solutions that contribute to the discovery of new battery materials and the advancement of lithium battery technology. Collaboration & Communication Contribute to academic and industry discussions by publishing research findings in top-tier journals and presenting at conferences. Engage in machine learning research aimed at addressing battery design challenges and enhancing system ability to interpret data-driven science efficiently. The ability to communicate complex concepts clearly and effectively to both technical and non-technical team members. Education and/or Experience: MS or PhD in Computer Science, Statistics, Computational Neuroscience, Cognitive Science or a related field, or equivalent practical experience. Strong foundational knowledge and practical experience in Machine Learning, Deep Learning, and Large Language Models. Proficiency in programming languages relevant to machine learning, with a strong preference for Python. Experience with deep learning frameworks such as PyTorch or TensorFlow. Proficiency in utilizing causal graphs for AI research and application. A solid track record of innovative research, preferably with published work in relevant areas. Excellent problem-solving abilities and a passion for tackling complex technical challenges. Preferred Qualifications: Experience with AI applications in material science or battery technology. Familiarity with the latest trends and methodologies in AI research, including algorithms such as GRPO.

Your Impact at Lila We are seeking a motivated and detail-oriented Senior Research Associate / Associate Scientist to join our high-throughput autonomous chemistry team. This is a hands-on role at the intersection of organic and inorganic synthesis, advanced characterization, and laboratory automation. You will design and execute high-throughput experiments, synthesize small molecules, and perform rigorous downstream analysis while working side-by-side with senior scientists to translate ambitious product goals into scalable experimental workflows that directly drive our company's growth. This position offers first-hand exposure to automated chemistry platforms, with real ownership over experiments that inform company strategy and scientific direction. Ideal candidates are execution-driven, thrive in fast-paced laboratory environments, and are eager to build deep technical expertise while contributing meaningfully to next-generation chemical discovery at Lila Sciences. What You'll Be Building Independently execute experiments to synthesize, purify, and characterize organic and inorganic small molecules Optimize reactions, perform method development, and interpret analytical data to guide project decisions Translate early-stage ideas into reproducible, functional experiments Apply retrosynthetic planning to support target molecule synthesis Operate Schlenk lines, gloveboxes, and other inert-atmosphere systems for sensitive compounds Use PAT tools (UPLC, LCMS, NMR, IR, Fluroescence, DLS) to monitor reactions, ensure quality control, and generate high-quality data for ML workflows Leverage automation and AI-driven platforms to accelerate workflows and reduce experimental cycle times Collaborate with engineers, ML scientists, and stakeholders to validate model-suggested conditions, analyze trends, troubleshoot issues, and communicate results clearly through reports, discussions, and presentations Document results, maintain accurate digital records and adhere to EHS and laboratory best practices What You'll Need to Succeed M.S. in Chemistry or related discipline (organic, organometallics, catalysis) with 2+ years of hands-on high-fidelity laboratory experience in an academic or industry setting, or B.S. + 5 years Hands-on experience in organic/inorganic synthesis, purification, chromatographic techniques, product analysis Strong understanding of retrosynthesis, reaction mechanisms, and method optimization workflows Proficiency with analytical techniques such as TLC, HPLC, LCMS, NMR, and IR Ability to follow SOPs and work safely with diverse chemical reagents and automated platforms Ability to thrive in a fast-paced, multidisciplinary research environment Required proficiency in using SciFinder, Reaxys, Chemdraw to search public database and literature Basic proficiency in Python or other scripting languages for data handling Good document practices, strong attention to detail and a proactive, problem-solving mindset Effective oral and written communication skills; contributed to internal reports, technical documentation, or peer-reviewed publications Bonus Points For Experience with high-throughput or AI-driven automated platforms Authored publications in peer-reviewed journals in chemical catalysis, organic methodology Ability to handle air/moisture/light sensitive compounds About Lila Lila Sciences is the world's first scientific superintelligence platform and autonomous lab for life, chemistry, and materials science. We are pioneering a new age of boundless discovery by building the capabilities to apply AI to every aspect of the scientific method. We are introducing scientific superintelligence to solve humankind's greatest challenges, enabling scientists to bring forth solutions in human health, climate, and sustainability at a pace and scale never experienced before. Learn more about this mission at *********** If this sounds like an environment you'd love to work in, even if you only have some of the experience listed below, we encourage you to apply. Compensation We expect the base salary for this role to fall between $80,000-$118,000 USD per year, along with bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact. We're All In Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy. A Note to Agencies Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

. . . . . GROWTH OPPORTUNITY BIOPHYSICAL CHEMISTRY | BIOCHEMISTRY MISSION STATEMENT: Develop BioPhysical and Biochemical Assays for screening and characterizing small molecules. Do your skills include the following? Biophysical methods: SPR for determining small molecule affinity to protein targets Biochemical assays: develop, analyze and troubleshoot (e.g. FRET, FP, AlphaScreen/LISA, ADPGlo) Protein characterization techniques: size exclusion chromatography, dynamic light scattering, DSF, TSA If you are answering YES - - Reach out to learn more about this exciting new opportunity: Call: ************ or Schedule a time: ******************************** or Email: ************************* Visit our Company Website - ************************ Visit our Career Opportunities Page - *****************************

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description Job Focus: A contractor position is available for a skilled scientist to join in Pfizer's Pharmacokinetics Dynamics and Metabolism New Biological Entities (PDM-NBE) ADME group to address diverse and complex scientific ADME issues pertaining to protein biotherapeutics. This lab based role involves the scientific and technical support of in vitro and in vivo pre-clinical studies designed to understand mechanistic ADME characteristics of biotherapeutics which will support the development of predictive pharmacological tools. The candidate will participate in all phases of laboratory operations relating to biotherapeutic PK/tissue distribution/tissue catabolism study execution, sample preparation, and data analysis. We are looking for a scientist passionate about learning and able to quickly apply new skills to the project needs. Responsibilities: • Independent sample preparation and analysis for in vitro and in vivo radiolabeled PK/drug tissue distribution/tissue catabolism studies using appropriate method of analysis (primarily gamma counter detection) • Handling of biological samples, preclinical serum and tissues • Occasional use of cell culture, SDS-PAGE, or binding assays may be required • Perform under minimal supervision; initiative in method development is expected • Independent daily operation, calibration, maintenance, and trouble shooting of instrumentation • Summarization and documentation of experiments Qualifications, Technical Skills and Experience: • BS/MS level education in Biochemistry, Biology, Pharmacology or closely related fields required • Industry experience in biopharma preferred • Experience using radioactive materials (125I, 111In) is strongly preferred • Experience with SDS-PAGE, binding assays, or cell culture is a plus • Knowledge of IACUC, animal use protocols, PKPD study design and concepts is a plus • High level of initiative in performing experiments, multi-tasking and troubleshooting • Fast learner and be able to master running/maintaining instruments after a short period of training • Strong interpersonal skills, communication (verbal and written) • Works well both independently and as part of a team. Collaborative skills and effective partnering skills in a matrix-environment is necessary • Strong data organization and analysis skills Additional Information Best Regards, Anuj Mehta ************

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of self-assembly nanostructures by exploiting a family of naturally occurring commensal viruses to create the first re-doseable and targetable medicines utilizing a variety of payloads, such as oligos, small molecules, and DNA. This approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad pipeline of novel, targeted medicines for disease with high unmet medical need. Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (NASDAQ:MCRB), , , and Indigo Agriculture. Summary of Role: We are seeking a highly motivated In Vivo Pharmacology Translational Scientist / Senior Principle Research Associate with an oncology background to work as part of a highly collaborative, fast paced team. The successful candidate will independently execute complex preclinical in vivo oncology studies. They will design, execute, and interpret efficacy, PK, and PD in vivo studies that drive translational decision-making across our pipeline. This role is hands-on requiring advanced technical expertise, is highly collaborative, ideal for a scientist who thrives in a dynamic startup environment and is passionate about turning data into actionable insights. You will work closely with discovery, biology, and translational teams to establish robust in vivo models, generate high-quality data, and support target validation and candidate progression. Key Responsibilities Design, plan, and execute complex in vivo oncology studies (including model development, efficacy, PK/PD, and mechanism-of-action studies) to support discovery and translational objectives Develop and optimize disease-relevant animal models aligned with human biology and clinical hypotheses Manage study execution, timelines, and logistics with minimal oversight, ensure complete, accurate and timely data capture and documentation. Perform hands-on in vivo procedures, including tumor implantation and measurement, dosing (IP, IV IM, SC), sample collection, and tissue processing Utilize a range of tumor models including xenograft, syngeneic and orthotopic models Analyze, interpret, and clearly communicate in vivo data to guide project decisions Collaborate cross-functionally with in vitro biology, bioinformatics, chemistry, and external partners Contribute to translational strategies, biomarker identification, and hypothesis-driven study design Maintain high standards of experimental rigor, documentation, and reproducibility Execute all work in compliance with IACUC and institutional polices Support CRO oversight, study planning, and data review where appropriate Required Qualifications BSc, MSc, or PhD in Biology, Pharmacology, Biomedical Sciences, or a related discipline Hands-on experience with in vivo models in an academic or industry setting Strong understanding of translational biology and how in vivo data informs human disease Experience with animal handling, dosing, imaging and necropsy procedures Ability to independently plan experiments and troubleshoot challenges Strong data analysis, record-keeping, and scientific communication skills Preferred Qualifications Industry experience in biotech or pharma Experience supporting immune-oncology programs and immune modulating modalities Hands on experience with xenograft and orthotopic tumor models in immunocompromised and humanized mouse strains Experience with in vivo bioluminescence and fluorescence imaging is highly desirable. Experience with GraphPad Prism for in vivo data analysis and visualization Experience with PK/PD studies, biomarkers, or translational endpoints Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The Scientist will contribute to Extractables & Leachables studies performed in the E&L laboratory at Boston Analytical to support client submissions. The ideal candidate will have experience operating LC-MS and GC-MS systems for analysis of volatile, semi-volatile, and nonvolatile organic extractables and leachables samples. PRIMARY DUTIES AND RESPONSIBILITIES • Prepares extractions for analysis. • Analysis of sample extract solutions by GC-MS and LC-MS to adequately resolve and identify all compounds. • Coordinate findings with the team to generate conclusions. • Author detailed cGMP report sections for work performed outlining study findings. • Develop analysis methods for drug product leachables testing. • Performs system maintenance and calibrations to ensure equipment is operating with specified requirements. Ensures all work performed strictly adheres to Company, client and Pharmacopial requirements. • Proper handling of hazardous waste in compliance with the Company and DES hazardous waste rules. REQUIREMENTS & QUALIFICATIONS Qualification includes a Ph.D. in Analytical Chemistry with 2+ years' experience or a Master's degree and 4+ years' experience or a Bachelor's with 6+ years' of experience performing and interpreting MS analysis. Knowledge of current Extractable & Leachables guidance (USP, ISO 10993) and best practices preferred. Experience working in a cGMP environment required. MINIMUM SKILLS REQUIREMENTS • Must have the ability and skill to perform the detailed job requirements noted above competently, safely and proficiently. • A self-starter, motivated person who possesses good interpersonal skills capable of effectively interacting with all departments and client personnel. • Must have excellent organizational, verbal communication and technical writing skills. • Must be a team player with integrity and concern for the quality of Company products, services and staff members. • Demonstrated LC-MS and/or GC-MS operation and data interpretation capability. • Ability to develop and optimize HPLC, UPLC, and GC methods. • Documented success managing complex projects to completion within customer expectations for deadline, cost, and overall deliverable

Weston & Sampson is seeking a full-time Senior Wetland Scientist and Permitting Specialist to support our permitting group in our Reading, MA office. The candidate will support multiple projects simultaneously and will have the opportunity to represent the company and our clients at public meetings, workshops, meetings with federal, state, and local agencies, and meetings with other stakeholders in conjunction with permit application review. Experience in regulatory permitting is a must. What you'll do: Preparation of federal, state, and local environmental permit applications and technical reports, including MA Wetlands Protection Act, Section 401/404 Permitting, Chapter 91 Waterways and MEPA/NEPA submittals Management of projects, understand and apply environmental regulations, develop schedules and budgets, mentor staff and communicate clearly and effectively to the public and clients Conduct wetland resource area delineations, wetland mitigation site design, construction period erosion and sediment control inspections and reporting Conduct environmental monitoring and mitigation to ensure consistent documentation and compliance with environmental requirements of permits/licenses What you will bring: Experience drafting and developing MA specific permit applications and documents (MEPA, WPA, Chapter 91) is a must Bachelor's degree in environmental/wetland science, biology, ecology, geology, engineering, planning, or related physical sciences disciple; Master's degree preferred 8-12 years of relevant professional experience in environmental permitting or consulting required; specifically, Massachusetts permitting Understanding of federal, state and local environmental regulations and permits (Army Corps Section 404/401, NEPA) Exceptional writing and oral communication skills Proven ability to work productively on multiple projects simultaneously as part of a multidisciplinary project team Willingness to travel (both in state and out of state in the northeast), prepare for and participate in public hearings Experience utilizing GPS equipment preferred Experience with ArcMAP or ArcPRO GIS software preferred Salary Range: $86,670 - $110,510 based on experience #LI-HYBRID Overview Weston & Sampson is an 100% employee-owned, full-service environmental and infrastructure consulting firm made up of more than 1,000 professionals, who work together to develop innovative, cost-effective solutions for our clients. Since our founding in 1899, Weston & Sampson's mission has been to protect, improve, and sustain the natural and built environment to enhance the quality of life. As we grow, we are seeking dedicated technical and professional individuals who want to collaborate on meaningful projects with a team that respects and values their ideas. Weston & Sampson offers a flexible work environment, competitive compensation, industry-leading benefits, and exciting career growth opportunities-all in a supportive and dynamic corporate culture that embraces diverse perspectives and recognizes people for their contributions. Weston & Sampson is an Equal Opportunity Employer. We embrace the rich perspectives and experiences that arise from people of different races, ethnicities, cultures, sexual orientation, gender identities, ages, socio-economic statuses, abilities, and religions, as well as other untapped groups, within our Weston & Sampson family and the communities we serve. Weston & Sampson is committed to the principles of Inclusion, Diversity, Equity, and Access (IDEA). Our goal is to foster a sense of belonging and equitable representation across our organization and to empower our employees to incorporate IDEA values into the work they perform. Your world is always changing, and so are we. Join us as we grow: *********************************************** A Note to Third-Party Recruiters: Weston & Sampson coordinates all recruiting and hiring at our company. We do not accept unsolicited resumes from third-party recruiters, staffing agencies, or related firms. Resumes are only accepted if a signed agreement is in place. All unsolicited resumes will be considered the property of Weston & Sampson. Weston & Sampson is not responsible for any fees related to unsolicited resumes. #midlevelprofessionals #seniorlevelprofessionals #LI-HYBRID

Site: North Shore Medical Center, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. Job Summary Summary As required by CLIA, the testing personnel are responsible for specimen processing, test performance and for reporting test results. Each individual performs only those tests that are authorized by the laboratory director and require a degree of skill commensurate with the individual's education, training or experience, and technical abilities. Works independently in an efficient and organized manner to assure accurate results and records. The work requires a professional level of knowledge to read and interpret accurately test results used by providers in the diagnosis and treatment of diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated the responsibility of the technical oversight of the laboratory including the day-to-day supervision or oversight of the laboratory operation and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I is responsible for supervision of assigned workstations including Quality Control (QC) review, training, competency assessment of staff and inventory management. Does this position require Patient Care?No Essential Functions -After success completion of orientation, training and competency assessment on all instruments/methods applicable to their role: -Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting and maintaining records of patient test results. -Maintain records that demonstrate that proficiency testing samples are tested in the same manner as patient samples. -Adhere to the laboratory's quality control policies, document all quality control activities, instrument and procedural calibrations and maintenance performed. -Follow the laboratory's established corrective action policies and procedures whenever test systems are not within the laboratory's established acceptable levels of performance. -Be capable of identifying problems that may adversely affect test performance or reporting of test results and either must correct the problems or immediately notify the general supervisor, technical consultant, technical supervisor, clinical consultant or director; and -Document all corrective actions taken when test systems deviate from the laboratory's established performance specifications. 42 CFR 493.**************. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) - American Society for Clinical Pathology Board of Certification (ASCP-BOC) preferred Experience lab experience 3-5 years required Knowledge, Skills and Abilities - The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. - Demonstrates advanced level of analytical skills and judgement. - Must have understanding of computer technology and its application to analytical procedures and quality control. - Must have comprehensive understanding of laboratory equipment and its operation, maintenance and repair and analytic techniques. - Must have the ability to work independently, evaluate situations and act appropriately. - Ability to multitask in a fast-paced environment. - Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. - Must be able to perform as a team member. - Excellent interpersonal skills. - Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. - Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical Requirements Standing Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 81 Highland Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Evening (United States of America) Pay Range $31.83 - $46.30/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: 3200 North Shore Medical Center, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health. Research Associate/Associate Scientist: We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs. This role is based onsite in our lab in Woburn, MA 5 days/wk. Responsibilities: Test and execute immunoassay workflows on high-throughput, semi-automated platforms Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects Assist in data analysis Acquire necessary equipment and supplies for various projects Qualifications: Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab Direct experience running biofluid-based immunoassays and qPCR experimentation is required Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.) Experience characterizing and troubleshooting immunoassays Strong proficiency in molecular biology lab techniques General Qualifications: Self-motivated and ability to perform complex tasks in an effective manner Ability to follow instructions and grow in a mentorship setting Excellent organizational and documentation skills Desire to learn and implement new technologies Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position. We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company. Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability. Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.

Piper Health & Sciences is seeking a full-time iPSC Production Scientist to join a growing organization's Bio/Engineering Production team onsite at their Massachusetts location. The ideal candidate will have a strong biology background and hands-on experience in iPSC stem cell culture, differentiation, and QC within a pharmaceutical or biotech environment. Responsibilities of the iPSC Production Scientist Include: * Full-time onsite schedule: Monday-Friday, 9:00 AM - 5:00 PM * Lead and support iPSC production and related lab activities * Perform hands-on stem cell culture and differentiation * Execute QC-related tasks in accordance with SOPs * Maintain accurate lab documentation and records * Support Bio/Engineering Production workflows * Follow all safety, GMP, and GLP standards Qualifications of the iPSC Production Scientist Include: * Biology degree is strongly preferred (Biomedical Engineering degrees are NOT a fit) * Proven hands-on experience with: * iPSC cell culture * Stem cell differentiation * Quality Control (QC) processes * Pharmaceutical or biotech industry experience preferred Compensation of the iPSC Production Scientist Includes: * Salary Range: $83,200.00 - $114,000.00 per year (equivalent to $40.00 - $55.00 per hour), based on experience and certifications. * Comprehensive Benefits: CIGNA Medical, Dental, Vision; 401k through ADP and sick leave as required by law. * Ability to work with a well renowned and growing organization that has a robust pipeline and quality culture. This job opens for applications on 1/12/2026. Applications for this job will be accepted for at least 30 days from the posting date. #LI-AW1 #LI-ONSITE keywords: Scientist, iPSC Production, stem cell culture, induced pluripotent stem cells, cell differentiation, quality control, QC, laboratory scientist, cell biology, biotechnology, pharmaceutical production, bioengineering, GMP, GLP, SOP compliance, tissue engineering, regenerative medicine, bioprocessing, cell therapy, stem cell research, lab operations, onsite scientist, Medford MA jobs, contract scientist, PhD biology, master's biology, postdoctoral research, biotech scientist, pharma scientist, cell culture specialist, stem cell specialist, iPSC scientist, QC scientist, bio production scientist, laboratory techniques, cell-based assays, biotech careers, pharma careers, stem cell manufacturing, cell culture workflows, life sciences jobs, biopharma jobs, laboratory compliance, scientific documentation, biotech industry experience, pharmaceutical industry experience, cell line development, research scientist, production scientist, laboratory QC, stem cell differentiation protocols, cell culture maintenance, full-time onsite scientist, bioengineering production team, regenerative biology, tissue culture, cell therapy manufacturing, biotechnology research, pharmaceutical QC, biomanufacturing, cell biology techniques, stem cell QC testing, scientific method, laboratory safety standards, GMP compliance, GLP compliance, biotech contract role, scientist contract position, iPSC culturing, stem cell production, biotech Medford MA, pharma Medford MA, scientific careers, laboratory scientist jobs, cell therapy scientist, bioprocess scientist, QC laboratory scientist, stem cell lab work, biotech production workflows, pharmaceutical production workflows, life sciences contract jobs, biotech contract scientist, pharma contract scientist.

Title: Toxicologist The Toxicologist will play a critical role in the assessment of the safety profile of small molecule drug candidates throughout the drug development process. This position requires a deep understanding of toxicological principles, regulatory requirements, and the ability to interpret complex data to inform decision-making. Responsibilities Conduct comprehensive toxicological evaluations of small molecules Analyze data from non-clinical studies to identify potential safety concerns and recommend strategies for risk mitigation. Prepare toxicology sections for regulatory submissions (INDs, NDAs) in accordance with FDA, EMA, and ICH guidelines. This will include liaising with the regulatory agencies related to toxicological data. Participate in project teams to provide expert advice on safety-related issues throughout the product lifecycle. Conduct risk assessments based on toxicological data to support decision-making processes regarding compound progression Profile Ph.D. or equivalent degree in Toxicology, Pharmacology, or a related field Mulitple years experience in the pharmaceutical or biotechnology industry. Small molecules experience Strong knowledge of GLP regulations, ICH guidelines, and FDA/EMA submission requirements. Experience working directly with regulatory agencies is an advantage. Benefits: Competitive salary with performance-based bonuses and comprehensive benefits package Home office option Excellent company culture

We are seeking a highly motivated and innovative Scientist to support the discovery and development of gene therapies for rare genetic diseases. The candidate is expected to have proven practical technical capability and experience in, cell culture and cell based assays, protein purification and analytical assays. She/he should be scientifically motivated and capable of critically analyzing and interpreting data and reporting experimental results. Strong presentation and communication skills and the ability to work in a fast-paced and team-oriented environment will be vital. The position will support the development of a pipeline of gene therapy - associated product concepts while working in a cross- functional and collaborative environment Skills: • Experience with mammalian cell culturing techniques and cell based assays. • Experience with PCR, qPCR, Southern / Western blotting, Experience with FPLC / HPLC systems. • Ability to work in a team orientated, collaborative environment Strong communication and presentation skills • Prior experience with production and purification of AAV vectors is a plus Keywords: Education: BS/MS with a minimum of 8 years of related experience Qualifications BS/MS with a minimum of 8 years of related experience

A biotechnology company in Waltham, MA is seeking a Principal Scientist in ADME-PK to enhance drug delivery to muscle and CNS tissues. The successful candidate will design preclinical studies, author regulatory documents, and collaborate across various teams. Candidates should possess a PhD in a relevant field and over 6 years of industry experience, with expertise in pharmacokinetics and drug metabolism. This role offers a competitive salary in the range of $159,000 to $195,000 USD depending on experience. #J-18808-Ljbffr