Senior scientist jobs in Maryland - 325 jobs

Principal Scientist (Residual Impurities)
MacRogenics, Inc. 4.8
Senior scientist job in Rockville, MD
Job Category: Development Apply now Posted : November 5, 2025 Full-Time On-site Headquarters 9704 Medical Center Dr Rockville, MD 20850, USA MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibody-based technologies. Our team of350+ dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer. Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe. The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics' corporate culture promotes an atmosphere of innovation, open communication and teamwork where employees can see firsthand how they contribute to the success of the organization. Summary of Position The Principal Scientist is a technical and strategic leader responsible for method development, qualification, transfer, and lifecycle management of residual impurity assays for biopharmaceutical products including monoclonal antibodies (mAbs), bispecifics, and antibody-drug conjugates (ADCs). This individual thrives in a cross-functional, fast-paced, and collaborative environment, applying strong troubleshooting ability, scientific rigor, and a results-driven mindset to support programs from early development through commercialization. The role demands high accountability, proactive planning, and timely execution of deliverables. The Principal Scientist will supervise and mentor team members while serving as a subject matter expert in residual impurity testing across Biopharmaceutical Development (BPD) and CMC teams. Responsibilities and Job Duties: Lead the development of fit-for-purpose and robust residual impurity assays (e.g., HCP, DNA, Protein, Enzyme, Surfactant etc.) to support biologic product development and release. Provide technical leadership and hands‑on troubleshooting for analytical methods and instrumentation to resolve issues efficiently and maintain method robustness. Own and drive method lifecycle activities including development, qualification, transfer to QC, and support method validation aligned with ICH and regulatory expectations. Ensure on‑time delivery of analytical method development and testing support for process development, process characterization, analytical comparability, and CQA assessment efforts. Manage project timelines for impurity analysis and proactively communicate risks, progress, and mitigation strategies to stakeholders. Collaborate with CMC teams and Regulatory Affairs to develop residual impurity control strategies, specifications, and regulatory submissions. Manage vendor activities and oversee outsourced work including critical reagents, HCP coverage analysis, and CRO support. Lead implementation of new technologies and data‑driven approaches to improve throughput and sensitivity of impurity assays. Author and/or review SOPs, technical protocols and reports, and regulatory filings. Foster a high‑performance culture by coaching and mentoring scientists, promoting scientific excellence, accountability, and ownership. Present findings and strategies at internal cross‑functional meetings, technical forums, and external conferences. Participate in industry consortia on relevant topics and align internal strategies with industry practice. Qualifications Education & Experience Ph.D. in Biochemistry, Analytical Chemistry, Chemical Engineering, Pharmaceutical Sciences or related discipline with 6+ years of related industry experience, including 5+ years on residual impurity method development; or Master's degree with 12+ years of related industry experience; or Bachelor's degree with 14+ years of related industry experience 2+ years of people management experience with demonstrated ability to coach, develop and motivate high‑performing teams Prior experience in preparing analytical sections of IND, BLA and regulatory responses. Knowledge, Skills and Abilities Deep knowledge of residual impurity assay development (e.g. ELISA for residual protein, qPCR for DNA) Excellent troubleshooting and problem‑solving skills, with a systematic, data‑driven approach to resolving technical challenges Strong sense of accountability and ownership; consistently delivers to project goals and regulatory milestones Ability to manage multiple projects and priorities in a dynamic, cross‑functional environment Skilled in stakeholder management, with clear, proactive, and collaborative communication style Strong technical writing skills and attention to detail in documentation and data review Experience mentoring and developing scientific staff; promotes open communication and teamwork Solid understanding of CMC strategy, regulatory expectations, and phase appropriate analytical requirements Strong track record of independent troubleshooting, root cause investigation, and method remediation for impurity assays Proven success in delivering high‑quality results on time, even under changing priorities and compressed timelines. Demonstrated leadership and influence in cross‑functional matrix environments Preferred Qualifications Familiarity with potency assays, physiochemical assays and other characterization assays Knowledge in novel techniques on detecting and analyzing residual impurities Strong publication record and external scientific presence Experience in fostering partnership with clients through CDMO service Supervisory Responsibilities Yes. This role may supervise Associate Scientist and/or Scientist Additional Information The annual rate of pay for this position ranges from $129,500 - $197,500. For non‑exempt roles, and according to applicable regulations, there may be the possibility for overtime pay. This role is eligible for the Company's discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Company's benefits programs, including medical / dental / vision / prescription coverage, employee wellness resources, 401(k) plan with employer match, access to an Employee Stock Purchase Plan, (ESPP), paid time off & paid parental leave benefits, and disability benefits. The annual pay rate range is described in good faith, and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidate's experience, qualifications, geographic location, and other factors permitted by law. The Company may ultimately pay more or less than the posted range, and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned, vested, and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company's sole discretion, consistent with the law. Statement MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race, color, national origin, sex, gender identity, sexual orientation, religion, age, disability, protected veteran status, or any other characteristic protected by federal, state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email ******************** or call ************** and/or 711 for TTD/TTY service. Equal Opportunity Employer/Veterans/Disabled Equal Opportunity Employer. This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor. We do not accept non‑solicited resumes or candidate submittals from search/recruiting agencies. #J-18808-Ljbffr
$129.5k-197.5k yearly 2d ago

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Chief Scientist - Earth Science Modeling
National Science Teachers Association 4.0
Senior scientist job in Silver Spring, MD
ERT is seeking a Chief Scientist with experience in meteorology or atmospheric sciences, or other earth sciences to support tasks at National Oceanic and Atmospheric Administration's (NOAA) Earth Prediction Innovation Center (EPIC). The primary objective will be to enhance the research-to-operations-to-research pipeline for the weather forecasting community with the goal of improving the overall accuracy and reliability of US National Weather Service weather models. All research and development will be guided by the NOAA open‑source science principles. Required Skills 15+ years of experience in position of increasing responsibility and leadership in the field of climate or earth systems science, weather modeling and forecasting, or a closely related discipline. Facility with the computational and technical operational components of handling and using earth systems data for large-scale forecasting. Must be able to pass a background investigation to obtain a security badge to enter the applicable government facility. Education MS degree in atmospheric science, earth science or closely related discipline. PhD preferred. Location This position supports work at NOAA's Silver Spring, MD facility with some telework permitted. Compensation The salary range for this role is $46,000 - 221,000/year. This range is a good faith estimate based on similar roles across the organization. ERT considers several factors when extending an offer of employment, including the location, scope, and associated responsibilities of the specific position, as well as a candidate's work experience, education/training, and key skills. Benefits All full‑time employees are eligible to participate in our flexible benefits package, which includes: Medical, Rx, Dental, and Vision Insurance 401(k) retirement plan with company‑matching 11 Paid Federal Government Holidays Paid Time Off (PTO) Basic Life & Supplemental Life Health Savings Account, Flexible Spending and Dependent Care Flexible Spending Accounts Short‑Term & Long‑Term Disability Employee assistance program (EAP) Tuition Reimbursement, Personal Development & Learning Opportunities Skills Development & Certifications Professional Membership Reimbursement Employee Referral Program Competitive compensation plan Discretionary variable incentive bonuses based on factors such as individual performance, business unit performance, and/or the company's performance Publication and Conference Presentation Awards with bonuses ERT is a VEVRAA Federal Contractor and Equal Opportunity Employer - All qualified applicants will be considered for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status. #J-18808-Ljbffr
$46k-221k yearly 4d ago
Cell Culture Scientist
Astrix 4.1
Senior scientist job in Bethesda, MD
Manufactures cell and gene therapies for phase I and II clinical trials; (2) processes hematopoietic stem cell grafts for transplantation; (3) develops new cell therapies; (4) performs in-process and lot release testing of cell and gene therapies; (5) develops new assays to test cell and gene therapies; and (6) prepares chemistry, manufacturing, and controls (CMC) documents for investigational new drugs (IND) and summary data for annual reports to the Food and Drug Administration (FDA). ROLES / RESPONSIBILITES Build and optimize a robust cGMP compliant platform for generation, expansion and cryopreservation of autologous induced pluripotent stem cells (iPSCs) from peripheral blood derived CD34+ cells. Differentiate iPSCs to retinal pigment epithelial cells (RPE) to develop an iRPE patch for a phase I clinical trial to treat "dry" age related macular degeneration. Update and validate SOPs related to CD34 expansion, iPSC culturing, and RPE differentiation Manage a day to day operation of GMP facility Maintain iPSC colonies and freeze their early passages. GMP and aseptic culturing of iPCSs and differentiation of patient iPSCs into Retinal pigment epithelium (RPE) and maintenance of those RPE cultures. This work will include: Preparing media, supplements, and reagents needed cell culture work. Maintaining the cell culture room biosafety level 2 standards and maintaining aseptic conditions in cell culture flow hoods, incubators, and prepare sterile tools needed for work with cell cultures. The cell culture maintenance work will require working for short periods of times on the weekends and some holidays. Work to characterize the iPSC colonies for their pluripotency. This will require: Immunostaining of iPSCs, preparing RNA and cDNA from iPSCs, and Performing qRT-PCR assays. Additionally they will perform three germ layer assay based functional characterization of iPSCs. This work will also include any cell types that act as control for his iPSC work. Prepare regulatory documents for FDA and technology transfer Coordinate transfer of lab-technology to Good Manufacturing Practice (GMP suite) Develop Standard Operating Procedures (SOPs) with the Contract Research Organization (CRO) in relation to the cell therapy project. DESIRED BACKGROUND · Prior cell culture experience is required · Prior experience working in a cGMP environment is required
$71k-105k yearly est. 3d ago
Staff Scientist (Mouse Research) (49679)
Gap Solutions 4.4
Senior scientist job in Maryland
The MPC is a full scale, busy, and in demand mouse phenotyping core that provides technical and scientific expertise for the phenotypic characterization of mouse models. The organization collaborates on projects with investigators across NIH on a diversity of mouse models utilizing state of the art equipment and comprehensive testing methodologies to assess multiple physiological and behavioral systems. The core is equipped to handle all aspects of comprehensive, complex and diverse phenotyping projects in the areas of cardiovascular, metabolic, pulmonary, neuromuscular, behavioral phenotyping and exercise physiology testing while providing scientific consultation and collaboration with NIH research labs. The position offers diverse and exciting opportunities for interdisciplinary collaboration, development of comprehensive expertise in mouse phenotyping and comparative medicine, the ability to shape and steer ongoing growth of the core. Position Objective: The core seeks an experienced candidate with a strong mouse research background to assist in both the technical and scientific aspects involved in the core's daily work and collaborations. In addition to performing mouse phenotyping study work in the core (50% of time), the candidate would have the scientific background required to work alongside core staff in areas including: scientific collaboration and communications with investigators, experimental design, data analysis and interpretation, and new method development. The candidate for the position is expected to be able to perform a variety of specialized in vivo mouse phenotyping techniques and have a strong background in comparative medicine and/or physiology. The candidate is expected to develop expertise in in-vivo murine testing including: neuromuscular and behavioral phenotyping on diverse models, exercise testing, muscle/nerve stimulation, cardiovascular system testing, pulmonary system testing, metabolic phenotyping, and microsurgery. The successful applicant will be expected to already be experienced conducting in vivo mouse research in multiple listed areas and would be expected to become proficient in all areas over time. The individual would have the experiential and educational background required to read relevant scientific literature, and possess general understanding of physiology to develop the necessary knowledge in all areas serviced by the core (neuromuscular, behavioral, cardiovascular, pulmonary, exercise, and metabolic phenotyping of mouse models) in order to oversee scientific strategic testing planning, experimental design, data analysis and interpretation, and follow up testing suggestions for diverse mouse models with our NIH collaborators, as well as to independently develop new testing methods, validate or refine new or existing methods, and serve as a core liaison to provide educational outreach to scientists and students at NIH. Duties and Responsibilities: Perform a variety of in vivo mouse phenotyping testing and methods. Understand applications of the core's diverse phenotyping method repertoire and possess the ability to strategically apply testing strategies to target model specific questions. Prepare summaries of experiments, contribute to the evaluation and discussion of results. Study, adapt, and/or develop new techniques needed to answer new research questions. Maintain detailed records of laboratory experiments, perform statistical analysis of data, prepare tables, charts, graphs, summaries, and other materials for inclusion in publications. Provide training and guidance to students, fellow and other staff members in the DIR in the use of equipment/laboratory methods, procedures, and techniques. Contribute as an author and co-author in the writing and preparation of scientific papers for publication in recognized journals. Attend training sessions for new methodologies and techniques as needed and participate in conferences to stay abreast of latest scientific developments. Develop new methods and techniques independently where training does not exist by reviewing literature and applying own scientific knowledge, aptitude and insights to find new approaches to answering questions. Qualifications Basic Qualifications: Exceptional candidates with a master's degree in an appropriate area of specialization and at least 5 years of mouse research experience with relevant hands-on skill and proficiency conducting in vivo mouse testing will be considered. Must have prior experience conducting technically complex experimental protocols. Candidate must be able to lift 40lbs weight, move quickly and quietly in small, confined spaces, get up and down from ground easily, stand for extended periods of time. Minimum Qualifications: PhD degree in an appropriate area of specialization with experience working with mouse models. DVM or VMD with animal model research experience and/or transitioning into the research field. Excellent written and oral communication skills. Positive person with strong customer service mindset. Proficient hands-on technical abilities and mouse handling skills required. Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects. *This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at ********************. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law.
$71k-103k yearly est. 8d ago
Support Scientist IV
STC 4.0
Senior scientist job in Greenbelt, MD
About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site with global collaborations Travel: Frequent (domestic & international field missions, scientific meetings) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $130K - $175K Job Description: The Support Scientist IV will serve as a senior researcher under the ATMOS contract at NASA GSFC, leading major research efforts in atmospheric science. This includes computational modeling, instrument development, and analysis of large satellite datasets. The role requires collaboration with scientists across institutions and management of junior researchers. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Plan and direct scientific research tasks in atmospheric science. Lead development of computational models and instrumentation concepts. Publish extensively and represent NASA at international conferences. Mentor and oversee other scientists within project teams. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements 10+ years of scientific research experience. 5+ years of leadership in scientific project management. Strong background in atmospheric science with proven publication record. Advanced programming expertise (FORTRAN, C/C++, Python). Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or M.S. degree in one of the listed disciplines, plus ten years of experience relevant to the position. This experience is in addition to the experience required for the position level.
$130k-175k yearly 60d+ ago
Senior Bioinformatics Scientist
BD (Becton, Dickinson and Company
Senior scientist job in Maryland
We are the makers of possible BD is one of the largest global medical technology companies in the world. Advancing the world of health is our Purpose, and it's no small feat. It takes the imagination and passion of all of us-from design and engineering to the manufacturing and marketing of our billions of MedTech products per year-to look at the impossible and find transformative solutions that turn dreams into possibilities. We believe that the human element, across our global teams, is what allows us to continually evolve. Join us and discover an environment in which you'll be supported to learn, grow and become your best self. Become a maker of possible with us. About us BD's Diagnostics Solutions business is seeking a Senior Bioinformatics Scientist to join a highly multi-disciplinary team developing new infectious disease diagnostic technologies. This individual will be expected to develop new methods and tools for data analysis and interpretation, including translating data into clinically actionable decision algorithms to support our customers and patients. The role will require extremely strong communication skills, and an ability to translate highly technical information into meaningful insights. Responsibilities: * Innovate, develop, train and validate automated algorithms to translate extensive microbiological datasets into clinically actionable decisions. * Collaborate to develop descriptive models and metrics from instrument platform data to enable exploratory data analysis and decision algorithm training. * Support project team activities by developing and maintaining algorithm and data analysis pipelines that collect, process and analyze, and display experimental data. * Collaborate with clinical and project teams to plan and analyze studies, experiments, and surveys; use statistics fundamentals to support and facilitate strategic decision making for management and project teams. * Program, document, and validate software code to execute data handling tasks, perform data analysis and produce data visualization results. * As a member of the R&D systems engineering and bioinformatics team, assist teams with identifying design risks and work to implement process improvement initiatives. * Serve as statistics and informatics subject-matter expert, mentor, and teacher to cross-functional teams * Present analyses and interpretations to internal and external customers. * Provide data analysis deliverables for projects to meet schedules and goals. * Review and/or prepare formal written reports/documents for distribution within and outside the department. QUALIFCATIONS Education: * Bachelor's degree in Computer Science/Engineering, Bioinformatics, Statistics or a related field is required * Masters degree in Computer Science/Engineering, Bioinformatics, Statistics or a related field preferred Required Experience: * 3+ years of equivalent experience * Proficiency with Python, R, or similar data scripting / programming language is required * Demonstrated database management skills and familiarity with SQL required * Strong communication skills and ability to discuss data, modeling, and analysis with technical and non-technical audiences * A high degree of professionalism, customer focus, and organizational skills is required * Self-Motivated Learner Preferred Experience: * Prior experience working within a regulated device or healthcare industry is preferred * Coursework or experience in statistics fundamentals * Ability to interpret project level requirements and develop programming specifications, as appropriate * Experience with Software production and Test management tools * Demonstrable scientific experimental design and data science experience preferred. * Clear understanding of fundamentals of biological sciences: specifically, biology or biochemistry experience * Knowledge in clinical microbiology is a plus. At BD, we prioritize on-site collaboration because we believe it fosters creativity, innovation, and effective problem-solving, which are essential in the fast-paced healthcare industry. For most roles, we require a minimum of 4 days of in-office presence per week to maintain our culture of excellence and ensure smooth operations, while also recognizing the importance of flexibility and work-life balance. Remote or field-based positions will have different workplace arrangements which will be indicated in the job posting. For certain roles at BD, employment is contingent upon the Company's receipt of sufficient proof that you are fully vaccinated against COVID-19. In some locations, testing for COVID-19 may be available and/or required. Consistent with BD's Workplace Accommodations Policy, requests for accommodation will be considered pursuant to applicable law. Why Join Us? A career at BD means being part of a team that values your opinions and contributions and that encourages you to bring your authentic self to work. It's also a place where we help each other be great, we do what's right, we hold each other accountable, and learn and improve every day. To find purpose in the possibilities, we need people who can see the bigger picture, who understand the human story that underpins everything we do. We welcome people with the imagination and drive to help us reinvent the future of health. At BD, you'll discover a culture in which you can learn, grow, and thrive. And find satisfaction in doing your part to make the world a better place. To learn more about BD visit ********************** Becton, Dickinson, and Company is an Equal Opportunity Employer. We evaluate applicants without regard to race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status, and other legally-protected characteristics. Required Skills Optional Skills . Primary Work Location USA MD - Sparks - 7 Loveton Circle Additional Locations Work Shift At BD, we are strongly committed to investing in our associates-their well-being and development, and in providing rewards and recognition opportunities that promote a performance-based culture. We demonstrate this commitment by offering a valuable, competitive package of compensation and benefits programs which you can learn more about on our Careers Site under Our Commitment to You. Salary or hourly rate ranges have been implemented to reward associates fairly and competitively, as well as to support recognition of associates' progress, ranging from entry level to experts in their field, and talent mobility. There are many factors, such as location, that contribute to the range displayed. The salary or hourly rate offered to a successful candidate is based on experience, education, skills, and any step rate pay system of the actual work location, as applicable to the role or position. Salary or hourly pay ranges may vary for Field-based and Remote roles. Salary Range Information $92,700.00 - $152,900.00 USD Annual
$92.7k-152.9k yearly 2d ago
Vulnerability Researcher / Exploit Developer
Redlattice
Senior scientist job in Maryland
At REDLattice, we are a global leader in providing differentiated cyber products and services. As we continue to evolve in a rapidly changing cyber landscape, REDLattice is seeking an experienced Mobile Vulnerability Researcher/ / Exploit Developer with a strong background in Computer Network Operations (CNO) and software development. We are driven by impactful and innovative projects that contribute directly to safeguarding our country and our strategic partners. Our teams are engaged in advanced vulnerability research and cyber solutions that meet the complex demands of our mission. With offices in Northern Virginia, Melbourne, Florida, Tel Aviv, Israel, and other locations, we are expanding rapidly to support the evolving needs of our customers and partners. Position Overview: REDLattice is seeking a seasoned Exploit Developer and Vulnerability Researcher with deep experience in Linux kernel development, reverse engineering, and offensive cyber operations. This role is ideal for professionals who thrive in low-level systems work and have supported organizations like USCYBERCOM or MARFORCYBER, contributing directly to Offensive Cyberspace Operations (OCO). Key Responsibilities: Conduct in-depth vulnerability research and exploit development across modern operating systems and architectures Reverse engineer binaries using tools such as IDA Pro, Ghidra, or Binary Ninja to identify novel attack surfaces and develop proof-of-concept capabilities Leverage knowledge of Linux kernels, SELinux, and AppArmor to develop and test exploits in hardened environments Collaborate with Cyber Mission Force (CMF) development teams to support OCO mission requirements Apply advanced understanding of exploit mitigations (ASLR, DEP, PXN, Stack Canaries, etc.) to bypass protections and deliver reliable results Work closely with capability developers and mission leads to design and refine modular, operationally-relevant cyber capabilities Document research findings, proof-of-concepts, and technical workflows in support of mission deliverables Required Qualifications: Active TS/SCI clearance with polygraph Bachelor s degree in Computer Science, Software Engineering, or related technical field (Master s preferred) 10+ years of experience in exploit research and development Strong background in reverse engineering, Linux kernel development, and low-level systems programming Experience with C/C++, Assembly, and Python (preferred) Familiarity with common exploit mitigations and bypass techniques Operational knowledge of USCYBERCOM/MARFORCYBER CMF development processes and methodologies (preferred) Technical Skills: Vulnerability Analysis & Exploit Development Reverse Engineering Tools: IDA Pro, Ghidra, Binary Ninja Kernel & Low-level OS Development Deep Linux internals knowledge (SELinux, AppArmor) Familiarity with mitigations: ASLR, DEP, PXN, Stack Canaries Programming Languages: C/C++, Assembly, Python (preferred) Why REDLattice: At REDLattice, we don t just follow the cyber landscape we define it. You'll work with some of the most talented offensive cyber professionals in the field, directly impacting mission success and national defense. We offer competitive salaries, comprehensive benefits, and unmatched opportunities for growth and innovation. How to Apply: Interested candidates should submit their resume via our web site ************************************ REDLattice is an equal-opportunity employer. We welcome applicants from all backgrounds and do not discriminate on the basis of race, color, religion, gender, age, national origin, veteran status, disability, or any other protected status.
$69k-97k yearly est. 60d+ ago
Scientist, Discovery
Arcellx Inc. 4.0
Senior scientist job in Rockville, MD
Who We Are Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible. Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work. What Matters to Us Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team. Arcellx Core Values * Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work. * Think 'we' before 'me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals. * Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right. How You'll Make a Difference As a Scientist, your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients. The "Fine Print" - What You'll Do * Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies. * Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed. * Develop new methods, technologies and processes when necessary for project. * Exercise significant technical discretion in the design, execution and interpretation of experiments. * Communicate progress and project recommendations to team members. Skills and Experience We Look For * BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience. * Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis. * Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation). * Preference for experience in drug development, immunology or protein engineering. * The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams. Rewards at Arcellx Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits. The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required. Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more. Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to **************** #LI-Onsite
$100k-120k yearly 46d ago
Sr. Scientist, Product Development - Custom Flavor Solutions
McCormick 4.4
Senior scientist job in Huntingtown, MD
You may know McCormick as a leader in herbs, spices, seasonings, and condiments - and we're only getting started. At McCormick, we're always looking for new people to bring their unique flavor to our team. McCormick employees - all 14,000 of us across the world - are what makes this company a great place to work. We are looking to hire a Senior Scientist, Product Development immediately at our Technical Innovation Center in Hunt Valley, Maryland. What We Bring To The Table: The best people deserve the best rewards. In addition to the benefits you'd expect from a global leader (401k, health insurance, paid time off, etc.) we also offer: * Competitive compensation * Career growth opportunities * Flexibility and Support for Diverse Life Stages and Choices * Wellbeing programs including Physical, Mental and Financial wellness * Tuition assistance POSITION OVERVIEW: Reporting to the VP of Custom PD, the Product Development Scientist will provide technical support for customers in the Custom Flavor Solutions business segment. The Product Development Scientist will establish, maintain, and drive best practices in customer intimacy engagement and product development, and will execute the creation of market preferred products through bench top product development, leveraging McCormick innovation and corporate technical resources. This role will provide technical leadership and expertise in McCormick's US Flavor Solutions technical community and will be responsible for substantial direct customer contact and involvement with internal McCormick business partners in addition to external customers. RESPONSIBILITIES: * Provide Seasonings Product Development expertise for Flavor Solutions' Consumer Goods customers creating market preferred products through bench top product development, leveraging culinary input, technical innovation and consumer insights * Deliver seasonings solutions in a cost-effective manner while driving technical insulation to provide competitive advantage in the marketplace * Design and execute project plans that deliver appropriate business return for our product development investment * Actively network within the industry to stay current with latest technology advances, customer requirements and consumer trends * Lead, guide and participate in various business and technical community programs and team projects REQUIRED QUALIFICATIONS: * BS or MS Degree in Food Science, Chemical Engineering, Chemistry or related technical field * Minimum 10 years of product development (PD) experience with at least 5 years of dry seasonings PD and expertise * Majority of PD experience in an industrial ingredient environment * High level of communication, presentation and collaboration skills across levels and functions * Knowledge of competencies and capabilities of the industry vendor community and McCormick competition * Experience solving complex technical challenges to deliver both market preferred flavors and excellent functionality * Ability to be flexible and adaptable to manage challenging clients and situations * Proven success multi-tasking in a fast-paced environment * High degree of ownership and professional commitment * Strong business sense and intuitive understanding of how to productively navigate within and adjust to various corporate cultures * Experience effectively collaborating across levels and functions within own organization and with outside customers and vendors * Strong understanding of seasoning ingredients and flavors, their major vendors, and performance attributes (including flavor, functionality, and quality) PREFERRED QUALIFICATIONS: * MS Degree and/or PhD in a related field * Experience with SAP, product formulary and retrieval systems and Microsoft software * Culinary interest or related training * Experience training and developing junior technical team members * Experience formulating and scaling up seasonings * Proficiency in vendor management and development including the implementation of new ingredients as required * Ability and willingness to travel 20-30% * Experience in developing products for snack food industry #LI-CG1 McCormick & Company is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law. As a general policy, McCormick does not offer employment visa sponsorships upon hire or in the future. === Base Salary: $86,390 to $151,220 Base salary compensation will be determined based on factors such as geographic location, skills, education, experience for this role, and/or internal equity of our current employees as part of any final offer. This position is also eligible to participate in McCormick's Incentive Bonus (MIB) Plan. In addition to a competitive compensation package, permanent employees of McCormick are eligible for our extensive Total Rewards programs that include: * Comprehensive health plans covering medical, vision, dental, life and disability benefits * Family-friendly benefits such as paid parental leave, fertility benefits, Employee Assistance Program, and caregiver support * Retirement and investment programs including 401(k) and profit-sharing plans WHY WORK AT MCCORMICK? United by flavor. Driven by results. As a McCormick employee you'll be empowered to focus on more than your individual responsibilities. You'll have the opportunity to be part of something bigger than yourself-to have a say in where the company is going and how it's growing. Between our passion for flavor, our 130-year history of leadership and integrity, the competitive and comprehensive benefits we offer, and our culture, which is built on respect and opportunities for growth, there are many reasons to join us at McCormick.
$86.4k-151.2k yearly 13d ago
Associate Scientist II, Molecular & Computational Biology
Tonix Pharmaceutical 3.8
Senior scientist job in Frederick, MD
About Tonix* Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace SymTouch (sumatriptan injection) 3 mg and Tosymra (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults. Tonix's development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA. Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md. Please visit ******************* for specifics on the pipeline. * All of Tonix's product candidates are investigational new drugs or biologics and have not been approved for any indication. Position Overview Tonix Pharmaceuticals is seeking a highly motivated Associate Scientist to join our multidisciplinary R&D team at the Frederick Research & Development Center. This role integrates computational protein structure analysis with hands-on molecular biology and protein biochemistry. The successful candidate will contribute to host-directed therapeutic discovery, antiviral platforms, and vaccine design by combining AI/ML-based protein modeling with molecular biology and protein science to generate, express, and analyze protein targets. Key Responsibilities * Perform protein structure modeling and design using platforms such as AlphaFold2/3, ESM, RFdiffusion, ProteinMPNN, and NetMHC. * Build and refine bioinformatics workflows for large-scale sequence and structural analysis of host and viral proteins * Perform molecular cloning, PCR, DNA and RNA isolation, bacterial transformation, and mutagenesis to generate expression constructs. * Carry out protein expression and purification followed by protein characterization * Collaborate with Tonix's imaging and cell biology teams to translate computational predictions into testable hypotheses in assays and animal models. * Contribute to the development of user-friendly computational pipelines and visualization tools for internal scientists. * Document and communicate results in reports, regulatory filings, and presentations to internal teams, collaborators, and external partners. * Maintain awareness of emerging computational biology technologies to enhance Tonix's drug discovery capabilities. Required Qualifications * B.S. or M.S. in Microbiology, Biochemistry, Bioinformatics, Computational Biology, or related field. * Hands-on experience with protein structure prediction and computational protein design tools. * Familiarity with core molecular biology and protein biochemistry methods (PCR, cloning, bacterial expression, Western blotting). * Strong communication skills and ability to work in cross-functional teams within Tonix's integrated discovery pipeline. Preferred: * Experience with cloud computing platforms (Google Cloud, AWS) for large-scale protein modeling. * Exposure to machine learning approaches in protein design and immunology. * Prior experience with protein engineering for therapeutic applications. * Track record of contributions to publications, posters, or conference presentations. * Proficiency in Python, especially ML/AI packages. Experience in Linux operating systems and shell programming is desirable. Recruitment & Staffing Agencies Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes. Compensation & Benefits Annualized base salary ranges from $60,000 to $90,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit. Tonix provides a comprehensive compensation and benefits package which includes: * Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs * Pet Insurance * Retirement Savings 401k with company match and annual discretionary stock options * Generous Paid Time Off, Sick Time, & Paid Holidays * Career Development and Training Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.
$60k-90k yearly 55d ago
Associate Scientist
Us Tech Solutions 4.4
Senior scientist job in Gaithersburg, MD
US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description • BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations. • This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data. • The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment. Qualifications Education: • Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field. Experience: • For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience. • For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience. Additional Information Special Skills/ Abilities • Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred. • Good documentation, writing and communication skills in a team based setting are essential.
$56k-84k yearly est. 1d ago
Lead Residual Impurity Scientist - Biologics
MacRogenics, Inc. 4.8
Senior scientist job in Rockville, MD
A biopharmaceutical company seeks a Principal Scientist to lead the development of residual impurity assays for biologic products. This role demands strong technical leadership, project management, and a collaborative spirit in a fast-paced environment. Candidates should hold a Ph.D. with over 6 years of relevant experience. The role offers significant support in both professional growth and performance-driven compensation. #J-18808-Ljbffr
$87k-114k yearly est. 2d ago
Chief Scientist, Earth System Modeling & Forecasts
National Science Teachers Association 4.0
Senior scientist job in Silver Spring, MD
A leading environmental organization is seeking a Chief Scientist in Silver Spring, MD. The ideal candidate will have over 15 years of experience in earth sciences, specializing in climate and weather modeling. This role involves enhancing NOAA's forecasting accuracy and leading research initiatives guided by open-source principles. Strong operational capabilities with earth systems data and a relevant advanced degree are required. Flexibility for telework is available, complementing a competitive compensation and benefits package. #J-18808-Ljbffr
$84k-114k yearly est. 4d ago
Scientist (49930)
Gap Solutions 4.4
Senior scientist job in Maryland
Position Objective: Provide services as a Scientist in support of the overall functions of the Flow Cytommetry Core on the NIH Bethesda campus by supporting collaborative research in the intramural community of the NIH. Duties and Responsibilities: Method Development: Establish best practices in conducting complex multi-parameter flow cytometry experiments through experimentation and testing of different methods and protocols. Evaluate and test fluorescent reagents available from commercial vendors and advise on their use. Identify and implement new flow cytometry-related technologies to enhance VRC's capabilities in deep profiling immune cells. Explore and be familiar with analytical tools available to conduct high-dimension data analysis. Develop protocols for sorting infectious samples, ensuring compliance with international safety standards. Training: Conduct routine basic and advanced training and educational efforts on flow cytometry methods and applications for researchers and collaborators, including safety and technical workshops for analyzers and cell sorters. Train staff and users on new equipment and ensure new equipment performs up to the existing standards and tolerances. Ensure that best practices in flow cytometry are implemented and educate FCC staff and VRC users accordingly. Work with VRC PIs to develop flow cytometric protocols, data analysis, and data presentation to ensure the highest level of quality. Operations: Support cell sorting projects with well-documented quality procedures and practices. Engage in risk assessment program for all active cell sorting projects and advise researchers accordingly. Calibrate and maintain laboratory equipment, troubleshoot issues, and update procedural manuals and methods for the FCC cell sorting facility. Analyze laboratory testing reports and maintain detailed logs of all work-related activities. Identify and address unexpected test discrepancies, recommending solutions. Interface with researchers, suppliers, reference labs, and equipment personnel to support operational needs. Qualifications Basic Qualifications: Ph.D., M.D., or equivalent degree in Immunology, Cell Biology, Biotechnology, or a related biomedical research field. A minimum of 5 years of relevant experience in flow cytometry and immunology. Demonstrated success in developing and implementing cutting-edge flow cytometry techniques. Experience in providing supervised and unsupervised single cell data analysis solutions for highparameter flow cytometry. Experience in setting up immunophenotyping pipelines for high-dimensional flow cytometry. Minimum Qualifications: Experience in working within a core/shared resource facility preferred. Ability to work independently, multitask, and pay close attention to detail. Strong written, oral, and visual communication skills. Ability and willingness to work on a team, excellent customer relations. Proficiency with Microsoft Word, PowerPoint, or other equivalent software suites *This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position. To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. GAP Solutions provides reasonable accommodations to qualified individuals with disabilities. If you need an accommodation to apply for a job, email us at ********************. You will need to reference the requisition number of the position in which you are interested. Your message will be routed to the appropriate recruiter who will assist you. Please note, this email address is only to be used for those individuals who need an accommodation to apply for a job. Emails for any other reason or those that do not include a requisition number will not be returned. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law. This position is contingent upon contract award.
$70k-103k yearly est. 3d ago
Support Scientist I
STC 4.0
Senior scientist job in Greenbelt, MD
About Science and Technology Corporation (STC): Founded in 1979, Science and Technology Corporation (STC) provides award-winning scientific, engineering, and technical services to U.S. Government and industry partners. We are dedicated to advancing our customers' missions through innovation, trusted partnerships, and science-driven engineering excellence. With integrity and precision, we deliver reliable solutions that make a real impact. At STC, we invest in our employees' growth, well-being, and success-fostering a culture of respect, trust, and empowerment. Join our world-class team and help shape the future of science and technology. Employment Category: Full-Time Location: Greenbelt, MD - On-site with some field support Travel: Some (domestic field campaigns, scientific meetings) Security Clearance: None Citizenship: Requires U.S. Citizenship Salary: $80K - $110K Number of Positions: 5 Job Description: STC is seeking a Support Scientist I to support the ATMOS contract at NASA Goddard Space Flight Center (GSFC). This entry-level scientist role provides research and analysis support to NASA scientists, including model development, data analysis, and operational instrument support. The Support Scientist I will contribute to scientific publications, proposals, and presentations. ATMOS is a NASA support services contract that provides advanced scientific, engineering, and technical expertise to enable Earth and space science missions. The program supports research, data analysis, technology development, and mission operations across multiple NASA centers. Through ATMOS, our teams deliver innovative solutions that help advance NASA's mission and expand scientific discovery. Key Responsibilities Include: Assist with modeling, instrument development, and data analysis. Provide scientific expertise in one or more areas of atmospheric science. Contribute to research proposals, peer-reviewed publications, and conference presentations. Support operations of scientific instruments at GSFC or during field missions. Benefits: Paid Time Off Starting at 80 hrs/yr, 11 Federal holidays, and 40 hrs/yr Sick Leave 401K with up to 4% employer matching contribution Comprehensive Medical, Dental, Vision Insurance, Short Term/Long Term Disability Flexible spending account Health savings account Tuition reimbursement Requirements Experience in scientific programming (FORTRAN, C/C++, Python). Familiarity with MATLAB, IDL, LabVIEW, or similar analysis tools. Record of academic or research publications desirable. Education: Ph.D. in atmospheric science, physical science, mathematics, or computer science, or M.S. degree in one of the listed disciplines, plus six years of experience relevant to the position. This experience is in addition to the experience required for the position level.
$80k-110k yearly 60d+ ago
Discovery Scientist
Arcellx Inc. 4.0
Senior scientist job in Rockville, MD
Arcellx (************************ is a clinical-stage biotech company headquartered in Gaithersburg, MD and Redwood City, CA. Arcellx is focused on the development of novel cell-based cancer therapies. A team of biotechnology professionals with expertise in biologics, discovery and tumor immunology incorporate proprietary technologies into genetically engineered human immune cells therapies. Arcellx's mission is to advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible. Primary Objective: Arcellx is seeking Scientists (levels Associate Scientist to Senior Scientist , depending on skill and experience) to collaborate in the innovation, discovery and development of protein and cell-based therapies. The successful candidate will work closely with a dedicated team of protein engineers and more broadly with scientists in other departmental groups (e.g. immunology, translation and manufacturing) to identify, produce, characterize and optimize recombinant proteins for use as therapeutic agents in a variety of oncology indications. The candidate will bring to the role expertise in protein engineering as well as a strong track record of innovation and creativity. Main Responsibilities: Responsibilities will depend, in part, on hiring level, but are likely to include some or all of the following: Collaborate with other scientists to design, generate and characterize recombinant proteins, including biopharmaceutical products. Develop and execute selection and screening strategies using phage, yeast and mammalian display. Evaluate existing and emerging technologies, techniques and tools enhance products and streamline discovery workflows. Independently plan, design, execute, record and analyze experiments. Summarize and present data in internal meetings and discussions. Write and review technical protocols and reports. Coauthor scientific abstracts, manuscripts and presentations. Manage and drive the advancement of internal projects, products or technology initiatives. Preferred Qualifications: Preferred qualification will depend, in part, on hiring level, but are likely to include some or all of the following: PhD in the life sciences (e.g. Biochemistry, Chemistry, Chemical Engineering, Biology, immuno-oncology), with minimum of 2 years post-degree experience in protein engineering. Extensive experience in the design, construction, expression, characterization and optimization of recombinant proteins. Experience with biopharmaceutical product design and lead optimization is ideal. Experience in the design and execution of selection and screening strategies, utilizing phage display (or a related display method). Proficiency with high throughput screening, sequencing and characterization of bacterial clones. Experience with optimizing expression yield and quality. Experience with multiple protein expression systems (e.g. bacterial, yeast or mammalian systems) is preferred. Experience utilizing and developing appropriate methods for assessment of protein-protein interactions (e.g. ELISA, Octet BLI, Biacore SPR, MSD) Experience with sequence analysis software (e.g. SnapGene, Sequencher, Lasergene, BLAST, etc.), including construct and primer design and sequence confirmation. Programming experience with Python and/or R (R Studio) is ideal. Experience in oncology, immunology, and translational research is ideal. Submit cover letter and resume to: ************** Without exception, applicants must submit both a cover letter and resume to be considered for these positions and must have experience as described above.
$75k-111k yearly est. Auto-Apply 60d+ ago
Associate Scientist II, Molecular & Computational Biology
Tonix Pharmaceuticals Inc. 3.8
Senior scientist job in Frederick, MD
Job Description About Tonix* Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya™ (cyclobenzaprine HCl sublingual tablets), a first-in-class, once-daily, non-opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement. Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace SymTouch (sumatriptan injection) 3 mg and Tosymra (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults. Tonix's development portfolio includes product candidates in central nervous system (CNS), immunology, immuno-oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases. Finally, the rare disease portfolio includes a product in development for Prader-Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA. Tonix owns and operates a state-of-the art infectious disease research facility in Frederick, Md. Please visit ******************* for specifics on the pipeline. *All of Tonix's product candidates are investigational new drugs or biologics and have not been approved for any indication. Position Overview Tonix Pharmaceuticals is seeking a highly motivated Associate Scientist to join our multidisciplinary R&D team at the Frederick Research & Development Center. This role integrates computational protein structure analysis with hands-on molecular biology and protein biochemistry. The successful candidate will contribute to host-directed therapeutic discovery, antiviral platforms, and vaccine design by combining AI/ML-based protein modeling with molecular biology and protein science to generate, express, and analyze protein targets. Key Responsibilities Perform protein structure modeling and design using platforms such as AlphaFold2/3, ESM, RFdiffusion, ProteinMPNN, and NetMHC. Build and refine bioinformatics workflows for large-scale sequence and structural analysis of host and viral proteins Perform molecular cloning, PCR, DNA and RNA isolation, bacterial transformation, and mutagenesis to generate expression constructs. Carry out protein expression and purification followed by protein characterization Collaborate with Tonix's imaging and cell biology teams to translate computational predictions into testable hypotheses in assays and animal models. Contribute to the development of user-friendly computational pipelines and visualization tools for internal scientists. Document and communicate results in reports, regulatory filings, and presentations to internal teams, collaborators, and external partners. Maintain awareness of emerging computational biology technologies to enhance Tonix's drug discovery capabilities. Required Qualifications B.S. or M.S. in Microbiology, Biochemistry, Bioinformatics, Computational Biology, or related field. Hands-on experience with protein structure prediction and computational protein design tools. Familiarity with core molecular biology and protein biochemistry methods (PCR, cloning, bacterial expression, Western blotting). Strong communication skills and ability to work in cross-functional teams within Tonix's integrated discovery pipeline. Preferred: Experience with cloud computing platforms (Google Cloud, AWS) for large-scale protein modeling. Exposure to machine learning approaches in protein design and immunology. Prior experience with protein engineering for therapeutic applications. Track record of contributions to publications, posters, or conference presentations. Proficiency in Python, especially ML/AI packages. Experience in Linux operating systems and shell programming is desirable. Recruitment & Staffing Agencies Tonix does not accept agency resumes unless contacted directly by internal Tonix Talent Acquisition. Please do not forward resumes to Tonix employees or any other company location; Tonix is not responsible for any fees related to unsolicited resumes. Compensation & Benefits Annualized base salary ranges from $60,000 to $90,000 plus target incentive; actual salaries will vary and may be above or below this range commensurate with several factors including experience, education, training, location, and merit. Tonix provides a comprehensive compensation and benefits package which includes: Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs Pet Insurance Retirement Savings 401k with company match and annual discretionary stock options Generous Paid Time Off, Sick Time, & Paid Holidays Career Development and Training Tonix provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, genetics, or any other characteristic protected by law. In addition to federal law requirements, Tonix complies with applicable state and local laws governing nondiscrimination in employment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfers, leaves of absence, compensation, and training. Tonix expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic, information, disability, veteran status, or any other characteristic protected by law.
$60k-90k yearly 26d ago
Vulnerability Researcher / Exploit Developer
Redlattice
Senior scientist job in Gambrills, MD
Job DescriptionVulnerability Researcher / Exploit Developer At REDLattice, we are a global leader in providing differentiated cyber products and services. As we continue to evolve in a rapidly changing cyber landscape, REDLattice is seeking an experienced Mobile Vulnerability Researcher/ / Exploit Developer with a strong background in Computer Network Operations (CNO) and software development. We are driven by impactful and innovative projects that contribute directly to safeguarding our country and our strategic partners. Our teams are engaged in advanced vulnerability research and cyber solutions that meet the complex demands of our mission. With offices in Northern Virginia, Melbourne, Florida, Tel Aviv, Israel, and other locations, we are expanding rapidly to support the evolving needs of our customers and partners. Position Overview: REDLattice is seeking a seasoned Exploit Developer and Vulnerability Researcher with deep experience in Linux kernel development, reverse engineering, and offensive cyber operations. This role is ideal for professionals who thrive in low-level systems work and have supported organizations like USCYBERCOM or MARFORCYBER, contributing directly to Offensive Cyberspace Operations (OCO). Key Responsibilities: Conduct in-depth vulnerability research and exploit development across modern operating systems and architectures Reverse engineer binaries using tools such as IDA Pro, Ghidra, or Binary Ninja to identify novel attack surfaces and develop proof-of-concept capabilities Leverage knowledge of Linux kernels, SELinux, and AppArmor to develop and test exploits in hardened environments Collaborate with Cyber Mission Force (CMF) development teams to support OCO mission requirements Apply advanced understanding of exploit mitigations (ASLR, DEP, PXN, Stack Canaries, etc.) to bypass protections and deliver reliable results Work closely with capability developers and mission leads to design and refine modular, operationally-relevant cyber capabilities Document research findings, proof-of-concepts, and technical workflows in support of mission deliverables Required Qualifications: Active TS/SCI clearance with polygraph Bachelor's degree in Computer Science, Software Engineering, or related technical field (Master's preferred) 10+ years of experience in exploit research and development Strong background in reverse engineering, Linux kernel development, and low-level systems programming Experience with C/C++, Assembly, and Python (preferred) Familiarity with common exploit mitigations and bypass techniques Operational knowledge of USCYBERCOM/MARFORCYBER CMF development processes and methodologies (preferred) Technical Skills: Vulnerability Analysis & Exploit Development Reverse Engineering Tools: IDA Pro, Ghidra, Binary Ninja Kernel & Low-level OS Development Deep Linux internals knowledge (SELinux, AppArmor) Familiarity with mitigations: ASLR, DEP, PXN, Stack Canaries Programming Languages: C/C++, Assembly, Python (preferred) Why REDLattice: At REDLattice, we don't just follow the cyber landscape - we define it. You'll work with some of the most talented offensive cyber professionals in the field, directly impacting mission success and national defense. We offer competitive salaries, comprehensive benefits, and unmatched opportunities for growth and innovation. How to Apply: Interested candidates should submit their resume via our web site ************************************ REDLattice is an equal-opportunity employer. We welcome applicants from all backgrounds and do not discriminate on the basis of race, color, religion, gender, age, national origin, veteran status, disability, or any other protected status.
$69k-98k yearly est. 2d ago
Associate Scientist
Us Tech Solutions 4.4
Senior scientist job in Gaithersburg, MD
US Tech Solutions is a global staff augmentation firm providing a wide-range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit our website ************************ We are constantly on the lookout for professionals to fulfill the staffing needs of our clients, sets the correct expectation and thus becomes an accelerator in the mutual growth of the individual and the organization as well. Keeping the same intent in mind, we would like you to consider the job opening with US Tech Solutions that fits your expertise and skillset. Job Description • BioProcess Engineering (BPE) department is responsible for scale up, tech transfer, and facility fit of clinical and commercial processes to manufacturing. BPE is also responsible for producing development drug substance material and data from pilot facilities. Members of Development Scale-up Center (DSC), within BPE, produce materials up to 500L scale for toxicology and process development studies, to confirm process performance and to troubleshoot issues in GMP facility, and work with cross functional team on technology evaluations. • This position is focused on upstream cell culture and fermentation processes supporting scalability and production of therapeutic proteins in DSC. Position is a hands-on laboratory and production-based role. Responsibilities include but are not limited to media preparations, routine sub-culturing of cells and fermentations. The candidate will assist in adaptation of transferred information for scale-up processes from late stage development to DSC as well as assisting in the production of various tox and development materials, troubleshooting and resolving technical issues with the production processes and/or equipment, identifying root causes for deviations, implementing corrective/preventative actions, assisting in implementing new technologies, and trending/analyzing data. • The candidate will assist in compiling data and expected to summarize and assist in interpreting results. The candidate will also maintain production and laboratory equipment. Qualifications Education: • Bachelor of Science (BS) or Master of Science (MS) in scientific, engineering or related field. Experience: • For the RA, we require a BS with 2 - 5 years or a MS with 0 - 2 years of relevant experience. • For the AS, we require a BS with a minimum of 5 years or MS with a minimum of 2 years of relevant experience. Additional Information Special Skills/ Abilities • Hands on proficiency in cell culture and/or fermentation and good aseptic techniques. Bioreactor/fermenter operation experience is preferred. • Good documentation, writing and communication skills in a team based setting are essential.
$56k-84k yearly est. 60d+ ago
Associate Scientist, CPD
McCormick 4.4
Senior scientist job in Huntingtown, MD
You may know McCormick as a leader in herbs, spices, seasonings, and condiments - and we're only getting started. At McCormick, we're always looking for new people to bring their unique flavor to our team. McCormick employees - all 14,000 of us across the world - are what makes this company a great place to work. We are looking to hire an Associate Scientist, CPD immediately at our Technical Innovation Center in Hunt Valley, Maryland. What We Bring To The Table: The best people deserve the best rewards. In addition to the benefits you'd expect from a global leader (401k, health insurance, paid time off, etc.) we also offer: * Competitive compensation * Career growth opportunities * Flexibility and Support for Diverse Life Stages and Choices * Wellbeing programs including Physical, Mental and Financial wellness * Tuition assistance POSITION OVERVIEW: The Associate Scientist will support product development initiatives within McCormick's U.S. Consumer Products Division (USCPD), contributing to innovation and renovation projects across McCormick's retail brands. RESPONSIBILITIES: * Develop and formulate products from concept through commercialization to meet consumer, regulatory, and manufacturing requirements. * Plan and prioritize project work to meet deadlines and business objectives. * Manage and protect proprietary technical information, including formulas, ingredient technologies, and manufacturing processes. * Collaborate with cross-functional teams (Marketing, Regulatory, Technical Services, Sensory, etc.) to share updates and align on project actions. * Partner with McCormick facilities and external co-packers to develop, launch, and optimize products; participate in plant trials as needed. * Communicate with ingredient suppliers to obtain information and samples to support development activities as directed by Senior PD staff REQUIRED QUALIFICATIONS: * Bachelor's degree in Food Science preferred, Chemistry or a related technical field considered * Minimum one year of product development experience in the food industry (co-op and internship experience will be considered) * Experience in effective collaboration in a team environment * Ability to adapt quickly to changing business priorities * Strong written and verbal communication skills * Strong decision-making skills * Passion for food and flavor * Curiosity and innovative thinking PREFERRED QUALIFICATIONS: * Experience developing new products * Culinary skills * Experience with SAP, product formulary, and retrieval systems #LI-CG1 McCormick & Company is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law. As a general policy, McCormick does not offer employment visa sponsorships upon hire or in the future. == Base Salary: $53,990 to $94,480 Base salary compensation will be determined based on factors such as geographic location, skills, education, experience for this role, and/or internal equity of our current employees as part of any final offer. This position is also eligible to participate in McCormick's Incentive Bonus (MIB) Plan. In addition to a competitive compensation package, permanent employees of McCormick are eligible for our extensive Total Rewards programs that include: * Comprehensive health plans covering medical, vision, dental, life and disability benefits * Family-friendly benefits such as paid parental leave, fertility benefits, Employee Assistance Program, and caregiver support * Retirement and investment programs including 401(k) and profit-sharing plans WHY WORK AT MCCORMICK? United by flavor. Driven by results. As a McCormick employee you'll be empowered to focus on more than your individual responsibilities. You'll have the opportunity to be part of something bigger than yourself-to have a say in where the company is going and how it's growing. Between our passion for flavor, our 130-year history of leadership and integrity, the competitive and comprehensive benefits we offer, and our culture, which is built on respect and opportunities for growth, there are many reasons to join us at McCormick.
$54k-94.5k yearly 10d ago

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