Senior scientist jobs in Santee, CA

This is a hybrid position, located in Vista, CA. Unfortunately, we are not able to provide visa sponsorship at this time. About the Company We are passionate about our mission to harness the amazing power of mushrooms for healthier lives. M2 Ingredients is the leading vertically integrated organic functional mushroom solution provider in the Western Hemisphere. We grow our portfolio of functional mushrooms indoors in our controlled, state-of-the-art facility in Vista, CA. M2 Ingredients sells its functional ingredients to global brands in the supplement, beverage and food channels. M2 Ingredients was founded in 2010 by Sandra Carter, a health and wellness expert with a PhD in preventative medicine, and Steve Farrar, a mycologist with over 30 years of experience in growing mushrooms. Both founders are active in the business. Position Summary: The R&D Principal Scientist will lead projects for testing method development & optimization for the M2 Ingredient business. The R&D Principal Scientist will be charged to lead projects related to the improvements of the M2 ingredient portfolio to improve the ingredients potency and bioavailability through strain selection, growth conditions, bioactive compound testing method development and ingredient processing. The R&D Principal Scientist will also participate in the operational readiness to ramp up and launch new ingredients on time, with a high level of quality and maximum customer availability. A successful R&D Principal Scientist is a creative and collaborative partner, is driven, organized, and detail oriented and is thoughtful and effective in problem solving and responding to the customer's needs. Position Responsibilities Collaborate with external labs to optimize and develop analytical methods to strengthen the M2 Ingredients product specifications. Develop and validate through testing the Finish Product Specifications of each new ingredient as it relates to the functional and nutritional benefits of the product. Support the FSQA team in investigation that involves testing method viability and accuracy. Actively participate in new ingredient development, from discovery and initial feasibility assessment to product qualification, business evaluation and commercialization such as new strain development to create ingredient specification that are more competitive in the marketplace. Contribute new ideas within the cross-functional team that drives the innovation pipeline at M2 Ingredients through scientific and technical insights. Ensure projects meet deadlines, quality and regulatory standards from ideation to full scale production by engaging the cross functional team on the project timeline and keeping the team informed and accountable throughout the development phases. Collaborate with CSO and Mycology team on creating patent filing submission dossiers and contribute to patent strategy. Qualifications M.Sc. in chemistry, biochemistry or other relevant science degrees. 5 + years of experience in the functional ingredients, dietary supplements or functional food industry in product development role including experience formulating, leading plant trials and production start-up. Laboratory experience or experience interpreting results for the following analytical methods an asset: mass spectrometry, DNA sequencing, chromatography, antibody assays. Experience managing external laboratories and contract research organization Excellent verbal and written communication skills. Proven ability to prioritize and organize workload to ensure timely delivery of tasks. Passion for product testing, food science and safety and quality in the food industry. Exceptional ability to identify and resolve problems efficiently and effectively by providing appropriate solutions. COMPENSATION & BENEFITS This full-time role will receive a competitive salary + benefits, including medical, dental, vision, PTO, 401k match. This position's anticipated annual pay range is $120,000 - $140,000 plus an annual bonus. Various factors are considered when determining an individual's compensation-including a candidate's professional background, education, certifications, experience, professional licenses, and location. Final offer amounts may vary from the amounts listed. We neither ask for nor consider the salary history of applicants. We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law. LOCATION M2 Ingredients is located in Vista, CA (about 35 miles north of San Diego and 60 south of Orange County). This position requires you to work full time, on-site in our Vista, CA location minimum of 3 days per week.

, please email ********************** We seek a highly qualified, motivated Scientist with a strong background in machine learning/generative AI to join the AI Platform at Sanford Laboratories for Innovative Medicine (Sanford Labs). Sanford Labs is an independent, not-for-profit biomedical research organization with a mission to discover and deliver the next generation of molecular medicines. RNA therapeutics are a rapidly expanding class of modalities (e.g., ASOs, si RNAs, mRNAs, and RNA aptamers) that can enable rapid clinical solutions. At Sanford Labs, you will help develop and implement AI/ML models and optimization paradigms to design best-in-class RNA therapeutics. As a Machine Learning Scientist, you will focus on designing and optimizing advanced AI/ML algorithms to address complex challenges in RNA therapeutics. You will develop and implement state-of-the-art architectures to enhance RNA sequence design, collaborating closely with interdisciplinary teams across Sanford Labs. This position offers an exciting opportunity to apply and refine cutting-edge machine learning methods while advancing innovative therapeutic solutions. The ideal candidate will have a strong foundation in machine learning, experience with modern AI architectures (e.g., transformers, diffusion models, or graph neural networks), and a keen interest in applying computational approaches to real-world problems in RNA biology and therapeutic discovery. Duties and Responsibilities: Develop innovative machine learning-based drug discovery algorithms and technologies to be applied across Sanford Labs' AI Platform. Implement AI/ML methodologies, including large language models and generative AI/ML, to address complex challenges in drug discovery. Monitor and evaluate the performance of AI/ML models and drug discovery solutions. Utilize software engineering best practices to develop complex AI applications at scale. Research and stay abreast of emerging technologies relevant to drug discovery and AI/ML. Proactively scope and deploy novel computational methods and digital technologies. Education and/or Experience: Doctorate or master's degree in computer science, mathematics, computational biology, bioinformatics, biomedical data science or a related field. Expertise in deep learning and machine learning. Strong experience with Python libraries for data science analysis (e.g., NumPy, Pandas, and Matplotlib) and deep learning (PyTorch or TensorFlow) Knowledge, Skills, and Abilities: Ph.D. in computer science, mathematics, computational biology, or bioinformatics, including industry experience. Deep experience in and theoretical understanding of statistical modeling, machine learning, deep learning, and other relevant quantitative methods. Familiarity with the latest AI architectures and frameworks, such as Transformer-based models, Graph Neural Networks (GNN), and other generative models including diffusion models, Variational Autoencoders (VAEs), and Generative Adversarial Networks (GANs). Knowledge of RNA biology, particularly RNA structure, function, and RNA-binding proteins. Fluency in scientific programming and tool development with Python, R, or equivalents. Proficiency in C++ or Java is a plus. Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for practical applications. Experience with software development good practices, including code versioning, documentation, and testing. Experience with cloud computing. Creative, open-minded, and passionate about scientific research. Demonstrated ability to thrive in a team environment. Strong interpersonal, collaborative, organizational, and presentation skills. Understanding of RNA therapeutic modality discovery and development. No relocation will be provided for this role; the candidate must be local to the San Diego, CA, region and/or the state of California. Supervisory Responsibilities: This position does not currently have direct reports. Perks and Benefits: Generous employer-paid healthcare for Medical, Dental, and Vision. 100% Employer Paid Life, STD and LTD 401(k) Employer Match Generous Vacation and Sick Leave 13 Holidays Closed over the Christmas and New Year Holiday Break

Representative responsibilities will include, but not necessarily be limited to, the following: Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically droplet digital PCR, HPLC, ELISA, culture of primary mammalian cells, and cell based potency assays. Participate in developing timelines, protocols and reports for assay transfers, qualifications / validations. Author and review QC analytical SOPs, protocols, and reports as needed Ensure the timely execution of all routine QC testing, data review, and preparation of summary reports Perform quality management activities such as deviation, CAPA, change control, investigation of OOS, OOT and anomalous results within the company QMS according to established procedures. Maintain QC laboratory, track critical reagents and equipment logbooks, and ensure all the equipment is calibrated Skills: Seeking a QC Scientist I with broad knowledge and expertise in cell-based potency assays, molecular biology assays, and chemical/biochemical assays as applied to AAV gene therapy products. The QC Scientist will be involved method development and/or method transfer. The QC Scientist will author and execute phase appropriate qualification/validation protocols and reports of QC methods to support product release and stability. The role will perform analysis on characterization, lot release and stability samples for clinical phase AAV Gene Therapy products. Education: BS or equivalent in relevant discipline with a minimum of 4 years of relevant industry experience or Master's degree in relevant discipline with a minimum of 1 year of relevant industry experience Experience in pharmaceutical industry with a GMP testing focus, ideally covering the analytical method and testing lifecycle from development through commercial drug product testing, with experience in a GMP QC release testing role Experience in an FDA-regulated environment Entrepreneurial spirit, with strong willingness to take on new challenges required to bring novel medicines to the clinic Excellent organizational and communication skills Experience with JMP statistical software a plus.

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • The new Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams. • This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as an Associate Scientist. • The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays. • A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. • Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel. Qualifications A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. • Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. Additional Information Sneha Shrivastava Technical Recruiter (Clinical/Scientific) Artech Information Systems LLC 360 Mt. Kemble Avenue, Suite 2000 | Morristown, NJ 07960 Office: ************ | Fax: ************ Connect with us on - LinkedIn | Facebook | Twitter

Job TitleScientist II-Immunoassay About Us Revvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world's greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our team of 11,000+ colleagues from around the globe are vital to our success and the reason we're able to push boundaries in pursuit of better human health. Find your future at Revvity Job Summary We're looking for a motivated scientist to drive the development and commercialization of flow cytometry-based multiplex bead assays within our LEGENDplex product portfolio. In this role, you'll contribute to new product development from concept through transfer to QC, Manufacturing, and Commercial teams, ensuring high-quality launches that support BioLegend's strategic goals. This position is ideal for someone who thrives in a fast-paced biotech environment, communicates effectively, and takes pride in owning projects from start to finish. You'll gain hands-on experience across the full product lifecycle while working within a collaborative and growing product development team. Essential Functions Reasonable accommodation may be made to enable individuals with disabilities to perform the essential functions. Design and conduct research and experiments in feasibility, optimization, and validation for Immunoassay product development Expertise in mammalian cell culture techniques Proactively manage and track active projects with potential deliverables to multiple business functions. Support immunoassay assay troubleshooting, root cause analysis, process improvement Complete all documentation, including Standard Operating Procedures, DMR Index, project records, and product instructions required for new product launch. Provide data driven updates and collaborate with Immunoassay Manufacturing and QC teams throughout the product development process Prepare technical reports, summaries, protocols, and quantitative analyses Conduct project-related information searches and literature searches Operate lab instruments according to procedures. Prepare reagents as required Contribute to scientific discussions and collaborations and present results Apply knowledge of scientific principles and concepts to the design, development, and execution of experiments. Other projects or responsibilities may be required Minimum Qualifications - Education and Experience PhD in Biological Sciences (e.g. biology, biotechnology, immunology, cell biology, biochemistry), or related field 5+ years of experience and strong knowledge of immunoassay methods used for protein analysis, with experience in at least one of the following assay formats: flow cytometry-based multiplex bead-based immunoassays (e.g. Luminex platform), ELISA, ELISpot, or ECL. Preferred Qualifications - Education and Experience Postdoctoral training is preferred Industry experience is preferred Proven research and publication track records Leadership and management experiences Working experience in manufacturing or product development setting in compliance with ISO13485 and MDSAP standards would be a plus Demonstrated proficiency with Excel, PowerPoint, GraphPad Prism, and Word Programs Excellent written and verbal communication skills and the ability to understand, prepare, and communicate technical scientific information to a wide range of audiences Highly organized and detail-oriented Enthusiasm, attention to detail, the ability to meet aggressive deadlines, and ability to work effectively with others in a fast paced, highly productive environment Excellent cross-functional team participation skills Results and goals oriented Commitment to quality Applicants must be currently authorized to work in the United States on a full-time basis for any employer. Work Environment & Physical Demands Lab While performing the duties of this job, the employee regularly works in a laboratory environment with occasional data entry on a computer. Occasional exposure to a warehouse environment. The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. While performing the duties of this job, the employee is regularly required to use hands and fingers to handle, feel, or operate objects, tools or controls, and reach with hands and arms. The employee is frequently required to stand, talk and hear. The base salary range for this full-time position is $118,000 - 147,500 . This range reflects the minimum and maximum target for a new hire in this position. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific salary range for your preferred location during the hiring process. Please note that base pay is only one part of our total compensation package and is determined within a range. This range allows for the successful candidate to have an opportunity to progress within the position and develop at our company. This base pay range does not take into account bonuses, equity, or other benefits which may be applicable and are dependent on the level and position offered. What do we offer? We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits: Medical, Dental, and Vision Insurance Options Life and Disability Insurance Paid Time-Off Parental Benefits Compassionate Care Leave 401k with Company Match Employee Stock Purchase Plan Learn more about Revvity's benefits by visiting our Bswift page. Log-In instructions are provided towards the bottom of the Bswift page. *For benefit-eligible roles only. Part-time and temporary roles may not be eligible for all benefits listed. Please reach out to your recruiter for more information. Revvity is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to any characteristic or status protected by applicable federal, state, and/or local laws. If you are an applicant with a disability that requires reasonable accommodation to complete any part of the application process or are limited in the ability-or unable to use-the online application system and need an alternative method for applying, you may contact ********************.

DTx Pharma Inc. is an RNA medicines company founded in 2017 and located in San Diego, CA. We are seeking highly motivated scientist(s) with experience in in vitro and/or in vivo pharmacology. The successful candidate will be a critical player in our efforts to break open new therapeutic areas for RNA medicines. Responsibilities: Assay development (Target engagement, PK) Characterization of hit/lead candidates in vitro and in vivo . Animal model characterization. New target identification Data analysis and presentation Requirements: MS or PhD with 3-5 years of experience post graduation, preferentially in a biotech or pharmaceutical company (but, not required). Exceptional candidates with a BS degree will be considered. Experience developing and executing in vitro assays (cell culture, transfection, qPCR, ELISA/Mesoscale, western etc.) In vivo experience (dosing, model development and characterization etc.) Knowledge of computer software and Microsoft applications (Word, Excel, PowerPoint, GraphPad Prism) Ability to work well in collaborative fast-paced team environment Demonstrate problem-solving and interpersonal skills. Optional but, a plus: Experience in ophthalmology, CNS and/or muscle disorders. Optional but, a plus: Experience with nucleic acid drugs (si RNA, Antisense etc.). Compensation: Competitive salary, health and dental insurance, benefits, 401k, stock options, gym etc. Keywords: biologist, scientist, si RNA, biotech, pharmaceutical, drug development, drug discovery, preclinical, animal models, antisense, CRISPR, eye, CNS, neurons

Scientist, Life Science Organic Chemistry Join our dynamic and cutting-edge research program focused on the health and chemical senses. As part of our multi-disciplinary discovery team, you will collaborate with our global R&D community to explore receptor-driven discovery of new bioactive ingredients and their industrial applications. We are seeking an exceptional and goal-oriented expert in the field of organic and medicinal chemistry. The ideal candidate will be an accomplished synthetic organic chemist with a proven track record of conducting science-based and computer-aided discovery of new bioactive and/or bio-functional molecules. DSM-Firmenich is a leading global provider of innovative solutions in nutrition, health, and sustainable living. We combine scientific expertise with cutting-edge technology to develop sustainable solutions that improve the quality of life for people today and for future generations. Our collaborative approach and commitment to excellence make us a trusted partner for our customers worldwide. **Your Key Responsibilities:** + Leverage expertise in organic chemistry and medicinal chemistry to design and synthesize small molecules with optimal properties. + Partner cross-functionally with other internal Science and Research domains including Biology, Computational Science, AI, and Machine Learning teams to speed up discovery + Work with Clinical Research Organizations to maximize the synthesis of libraries and specific compounds. + Maintain and understanding of relevant cutting-edge science (e.g. new chemistries & medicinal chemistry techniques and principles) and technology trends (e.g. automation) to propose new creative solutions or ideas to address technology gaps and save cost. + Analyse and present chemistry and SAR data at internal and external meetings and conferences + Draft and submit invention disclosure, publication manuscripts, and lab reports **We Bring:** + A science led company with cutting edge research and creativity everywhere - from Science and Research breakthroughs to sustainability game-changers, you'll work on what's next + A unique career paths with growth that keeps up with you - you join an industry leader that will develop your expertise and leadership + A chance to impact millions of consumers every day + A community where your voice matters + A culture that lifts you up - with collaborative teams, shared wins, and people who cheer each other on. + Competitive pay, career growth opportunities, and outstanding benefit programs. **You Bring:** + Up to 5 years ofpost-PhD experience (or equivalent) in organic or medicinal chemistry in an academic, biotechnology, or pharmaceutical environment + Knowledge in modern medicinal chemistry and lead optimization techniques, including multi-parameter bioactivity and physicochemical properties optimization + Strong synthetic and analytical chemistry skills with ability to design and implement multi-steps synthesis and characterization of complex molecules + Familiarity with molecular modeling and other computational tools useful for speeding up the discovery of bioactive small molecules + Great team player and excellent communicator with a strong drive for collaboration, excellence, and impact + Ability to innovate and thrive in a multidisciplinary environment The salary or hourly wage scale provided reflects the pay range dsm-firmenich expects to pay the successful candidate for the position. Individual pay offered will be based on the applicant's job-related skills, experience, relevant education, or training, and primary work location. This position is also eligible for bonuses and benefits, which are not included in the pay scale provided. Salary $97,000-$139,000. **About dsm-firmenich** At dsm-firmenich, we don't just meet expectations - we go beyond them. Join our global team powered by science, creativity, and a shared purpose: to bring progress to life. From elevating health to making fortified food and sustainable skincare, the impact of your work here will be felt by millions - every single day. Whether it's fragrance that helps you focus, alternative meat that's better for the planet, or reducing sugar without losing flavor, this is where you help shape the future of nutrition, health, and beauty for everyone, everywhere. And while you're making a difference, we'll make sure you're growing too. With learning that never stops, a culture that lifts you up and the freedom to move across businesses, teams, and borders. Your voice matters here. And your ideas? They're essential to our future. Because real progress only happens when we **go beyond, together** . **The application process** Interested in this position? Please apply online by uploading your resume in English. **Inclusion, belonging and equal opportunity statement** At dsm-firmenich, we believe being a force for good starts with the way we treat each other. When people feel supported, included, and free to be themselves, they do their best work - and that's exactly the kind of culture we're building. A place where opportunity is truly equal, authenticity is celebrated, and everyone has the chance to grow, contribute, and feel they belong. We're proud to be an equal opportunity employer, and we're serious about making our hiring process as fair and inclusive as possible. From inclusive language and diverse interview panels to thoughtful sourcing, we're committed to reflecting the world we serve. We welcome candidates from all backgrounds - no matter your gender, ethnicity, sexual orientation, or anything else that makes you, you. And if you have a disability or need any support through the application process, we're here to help - just let us know what you need, and we'll do everything we can to make it work. **Agency statement** We're managing this search directly at dsm-firmenich. If you're applying as an individual, we'd love to hear from you. We're not accepting agency submissions or proposals involving fees or commissions for this role

Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************

Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities * Maintain a well-documented laboratory notebook * Track progress against project timelines, generate regular status updates, and communicate progress and issues to management * Perform tasks across projects * Manage time effectively to meet deadlines * Adhere to safe laboratory practices * Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: * B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry * 0-3 years of experience working in a chemistry laboratory * Experience with a wide range of analytical techniques, especially HPLC * Ability to quickly learn new procedures and techniques Preferred: * Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting * Experience with solid-phase peptide synthesis (automated and/or manual) * Prior experience in a pharmaceutical or biotechnology environment

R&D Scientist - NGS Technology and Applications title depends on qualification and experience) Universal Sequencing Technology (UST) Corporation (universalsequencing.com), a leading NGS technology company engaged in long range/long read sequencing technology and single cell sequencing technology development, headquartered in greater Boston with a branch in San Diego, is looking for an outstanding R&D scientist to join our NGS technology and product development team in San Diego. This position is a unique opportunity to work on a cutting edge NGS library technology which enables many previously unachievable applications, especially in the clinical space. This person will work closely with a team of molecular biologists, bioinformatics scientists, instrument engineers and manufacturing specialists to develop a revolutionary single cell sequencing technology. He/she will play a key role in the development and validation of the technology as well as the commercial launch of products. He/she will also interact with external collaborators and early access customers, and provide technical support. The ideal candidate should have extensive cellular and molecular biology experience. He/she must have direct experience on cellular assay development and RNA manipulation; strong project management skills; ability to take initiative; effective verbal and written communication skills; and be an excellent team player. RNA-Seq, NGS library preparation, and sequencing data analysis skill under both Linux and Windows environment are desired; Molecular biology reagent kit development experience is a plus. Key Responsibilities: Lead NGS based single cell sequencing assay and reagent kit development Establish product quality control assays for in-process & final product test and deliver well-characterized & robust processes to manufacture Design and execute experiments, and analyze data independently Support current product improvement and commercialization Interact with collaborators and customers to promote UST technology and product Qualifications: Ph.D. in molecular biology, cellular biology, biochemistry or related fields (M.Sc. with exceptional experience will be considered) Minimum 3-years of cellular assay development and gene expression profiling experience Single cell sequencing library preparation, immune repertoire sequencing or early tumor detection experience is a plus Product development experience is preferred

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at ******************* Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Chemical Research Job Category: Scientific/Technology All Job Posting Locations: San Diego, California, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at *******************/innovative-medicine We are searching for the best talent for Scientist, Oligonucleotide Chemistry in San Diego, CA. Purpose: RNA Therapeutics and Delivery is embedded in Cell & Genetic Medicines, an organization within Therapeutics Discovery, where we are committed to the development of high-quality drug candidates in the Oligonucleotide Therapeutics space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific knowledge and expertise in several fields including oligonucleotide chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers growth opportunity within a dynamic and science driven organization. You will be responsible for: Perform solid phase synthesis, purification, and analysis of oligonucleotides and bioconjugates in a team environment. Support and trouble-shoot process development efforts for synthesis and characterization of oligonucleotides and their bioconjugates with higher throughput and automation. In collaboration with the team, support oligonucleotide analytical efforts, optimization and design for de-risked, tissue-specific delivery. Collect, document and evaluate experimental data and communicate scientific findings as verbal presentations and written reports. Qualifications/Requirements: Education: Minimum of a B.S./B.A. with a minimum of 2-4 years of experience, performing progressively advanced duties at the Associate Scientist level, or the equivalent training/experience is required. Advanced degree is preferred. Skills/Experience: Required: Hands-on experience with an emphasis on si RNA and/or ASO nucleic acid therapeutics synthesis and development. Experience in si RNA synthesis, purification, and analytical characterization Familiarity with the oligonucleotide delivery and drug discovery process Critical thinking and scientific skills and a demonstrated ability to interpret and clearly communicate data Strong team player with the ability to work effectively in a dynamic, matrixed team environment with diverse views Ability to adapt to changing priorities and timelines Preferred Qualifications: Experience in operating instruments and equipment including MerMade and Dr. Oligo synthesizers, as well as HPLC, LC-MS, and UV/Vis purification and characterization instrumentation. Experience in increasing throughput and automation of oligonucleotide synthesis, characterization and documentation processes. Knowledge and experience with delivery of oligonucleotides using bioconjugation strategies. Knowledge of RNA biology and oligonucleotide screening technologies to facilitate effective team collaboration. The expected pay range for this position is $76,000 to $121,000 The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/ performance year. Bonuses are awarded at the Company's discretion on an individual basis. Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave - 80 hours in a 52-week rolling period10 days Volunteer Leave - 32 hours per calendar year Military Spouse Time-Off - 80 hours per calendar year For additional general information on company benefits, please go to: ********************************************* This job posting is anticipated to close on December 11, 2025. The Company may however extend this time-period, in which case the posting will remain available on *************************** to accept additional applications. The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please contact us via *******************/contact-us/careers or contact AskGS to be directed to your accommodation resource. Required Skills: Preferred Skills: Analytical Reasoning, Chemistry, Data Analysis, Data Reporting, Drug Discovery Development, Execution Focus, Innovation, Interdisciplinary Work, Laboratory Experiments, Process Oriented, Quantitative Research, Research Ethics, Research Informatics, Scientific Evaluation, Scientific Research, Technical Writing, Technologically Savvy The anticipated base pay range for this position is : $76,000 to $121,000 Additional Description for Pay Transparency: Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation -120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year Holiday pay, including Floating Holidays -13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave - 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave - 10 days Volunteer Leave - 4 days Military Spouse Time-Off - 80 hours Additional information can be found through the link below. *********************************************

Qualifications: • General knowledge of Biology, Immunology, Flow Cytometry or other related discipline. • Familiarity with operation of routine laboratory instruments. • Effective oral and written communication skills. • Effective interpersonal skills. • Effective analytical and problem solving skills. • Demonstrated ability to to follow established policies and procedures. • Demonstrated ability to interpret and present data of simple to moderate complexity. • Demonstrated ability to keep accurate and complete laboratory records and logs. • Previous experience with Flow Cytometry and related software is a plus. Education and Experience: • Minimum Bachelor's degree in a biological science discipline • Minimum 0-2 years of relevant experience Responsibilities: The Scientist I is responsible for assisting in the development and evaluation of new reagents and enhancements to existing reagents. Executes experiments independently and evaluates and discusses data. Presents and explains material of simple to moderate complexity and prepares protocols and other documents. Has job skill and technical knowledge to perform established procedures. Under general supervision, plans, designs and performs reagent development activities. Work focus includes areas of Immunology, Cell Biology and Stem Cells using techniques such as multi-parameter flow cytometery, cell stimulation and cell culture assays. Direction is defined jointly with supervisor to meet short and mid-term goals. This position will regularly work with human and laboratory animal tissues. Primary duties include the following: • Performs experiments to evaluate new reagents using flow cytometer.. • Prepares protocols, reports and summaries. • Tabulates and analyzes experimental dat Qualifications Minimum Bachelor's degree in a biological science discipline Additional Information College degree or HS Diploma with +5 years biopharmaceutical industry experience

HD Biosciences, Inc. (San Diego), a WuXi AppTec Company, is expanding its in vitro Pharmacology. We're seeking highly skilled and motivated Scientist II to lead assay development projects and support target discovery and validation efforts for HTS and assay screening group. **Responsibilities** - Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required. - Normally receives minimal instructions on routine work and detailed instructions on new assignments. - Works under close supervision from supervisor or senior personnel. - Performs support functions (e.g. Runner function) in the (fill in Specific Dept.) - Ability to work in a team environment and independently as required - Maybe required to work Holidays and weekends - Maybe required to work Overtime ( Remove only for Exempt positions) - Contributes to the overall operations and to the achievement of departmental goals - Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures. - Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices - Other duties as assigned - May be required to assist in other departments Job Requirements: - Design, implement, and perform projects for functional assay development. - Proven hands-on experience with cell based assays and biochemical assays. - Support target discovery and validation efforts by independently developing and performing assays to evaluate biologic drug targets and candidates, such as GPCR, Ion-channels, Enzymatic assay, kinase assays, etc. - Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats. - Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques. - Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred - Scientific creativity, critical thinking and fast learning capabilities. - Industrial drug R& D experience is a plus - Effectively communicate with internal team colleagues and external clients to promote a world-class services. **Qualifications** - 5-10 years of relevant experience or equivalent - Master or PhD degree preferred in Biochemistry, Biotechnology or Molecular Biology. - Demonstrated strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology - Industry experience in Pharma/Biotech or close exposures to R&D process is preferred. Prior work in CRO in a commercial setting will be considered an additional strength. - Outstanding written and oral communication skills, and interpersonal skills to seamlessly fit within a teamwork driven environment. Knowledge / Skills / Abilities: - Proficient in Oral & Written communication skills - Need to be able to read, write and understand English (Mandarin) - Proficient in Microsoft (Excel, Word, Outlook) - Travel is required X% , Domestic/International, Daily / Overnight Physical Requirements: - Must be able to work in an office environment with minimal noise conditions. - Must be able to work in Lab setting with exposure to Animals/biohazards / Chemicals (List specific Chemicals) - Must not have animal allergies to applicable species in this facility - Must be able to wear appropriate PPE - Must be able to work in environment with variable noise levels - Ability to stand /Sit/walk for long periods of time - Ability to Lift 10 lbs routinely - Ability to crouch, bend, twist, and reach - Ability to push/pull 10 lbs routinely/ often / occasionally - Clarity of Vision - Ability to identify and distinguish colors - Must be able to perform activities with repetitive motions - Ability to climb Ladders / Stairs / Scaffolding - Ability to work in variable temperatures high to freezing - Inside/outside working conditions Anticipated salary range: $80,322 to $104,00 An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management. **Need help finding the right job?** We can recommend jobs specifically for you! An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability (************************************************************************************************** **Job Locations** _US-CA-San Diego_ **Job ID** _2025-13857_

How you will contribute: We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company. What you will be working on: Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing. Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes. Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color. Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing. Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research. What you bring to Plantible: B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering. 3 to 5+ years of industry experience in assay development in an industrial environment. Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer. Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes. A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action. Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred. Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills. Excellent verbal and written communication and presentation skills. Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment. Thrive in a fast-paced environment where the primary focus is on simplification and optimization. Choose Plantible Foods Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment. At Plantible we are continually working on our offerings to foster the best team. Check it out! Competitive health and wellness benefits Medical, Dental and Vision Insurance Discretionary Unlimited PTO Program Paid Holidays 401k Program Career Stipend Career development and growth opportunities Working in a rapidly growing, flexible and entrepreneurial environment Team building and company-wide events Financial support with your relocation, if necessary, ensuring a smooth transition Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time. If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description • The candidate will be a key member of the Ion Channel/GPCR/Transporter Pharmacology group, and provide experimental support for programs from target nomination through declaration of a clinical candidate. S/he will assist with the characterization of Client membrane targets, MoA studies and the development of HTS assays. • A MS degree with a minimum of 3 - 5 years of experience or a BS degree with a minimum of 4 - 8 years of laboratory experience is required. Hands- on expertise with plate-based assays, molecular biology, biochemistry, binding assays and cell culture techniques is essential. Working knowledge of ion channel, transporter or GPCR pharmacology is preferred. This position will be located in La Jolla, CA and may require up to 10% travel. Additional Information Best Regards, Anuj Mehta ************** Morristown, NJ 07960

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy