Senior scientist jobs in Warwick, RI

Machine Learning Scientist - LLM Systems for Scientific Discovery About the Team Join the internal AI initiative of a prominent venture studio that has launched 100+ life sciences companies (including Moderna). You'll be part of a ~20-person technical team in Cambridge building advanced LLM and ML systems that accelerate scientific breakthroughs and help launch new AI-first ventures. What Will I Be Doing: Research & prototype novel LLM workflows (agents, reasoning systems, tool-use frameworks) tailored to scientific applications Define success metrics and design custom benchmarks to evaluate AI systems across diverse scientific domains Collaborate with ML engineers to scale promising prototypes into production systems Stay at the frontier by synthesizing state-of-the-art research and validating findings through rigorous experimentation Build feedback loops that incorporate user testing into system development What We're Looking For: PhD in machine learning, computer science, statistics, physics, mathematics, or related quantitative field Research excellence in LLMs or adjacent areas (reasoning/agents, sequence modeling, representation learning, optimization) demonstrated through publications at top venues or impactful work Hands-on ML experience with PyTorch or JAX, including reproducible experiment workflows Strong Python skills and fluency with standard ML tools Ability to work independently while collaborating effectively in a small team Experience building LLM systems: agentic frameworks, RAG, multi-agent simulations, RLHF/DPO, or evaluation methodologies Domain knowledge in chemistry, biology, physics, materials science, or related fields What's in it for me: Competitive Compensation: $140k-$240k dependent on experience Work on originating and fostering breakthrough ventures transforming human health and sustainability Relocation assistance available (typically $10k sign-on bonus) Apply now for immediate consideration!

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. Join a world-class research team dedicated to reducing the impact of natural hazards and climate risks. FM is a market leader in commercial and industrial property insurance and loss prevention, serving over one-third of FORTUNE 1000 companies with engineering-based risk management and property insurance solutions. FM helps clients maintain business continuity through state-of-the-art engineering and research. The Structures and Geohazards Research Group at FM is seeking a creative and self-motivated Senior Research Scientist with a strong foundation in wind engineering and a specialized focus on computational wind engineering (CWE). The ideal candidate will possess deep expertise in fluid dynamics, high-performance computing, and wind tunnel testing, along with a demonstrated ability to conduct innovative, high-impact research. This role is integral to a strategic research initiative aimed at advancing the understanding of wind-related hazards and developing effective mitigation strategies. The successful candidate will contribute to cutting-edge projects that blend computational modeling with experimental validation to address real-world challenges in wind engineering. Responsibilities: Develop computational fluid dynamics (CFD) models to simulate wind flow around buildings and infrastructure, capturing complex aerodynamic interactions. Analyze wind loading on structures using high-resolution simulations; validate results with wind tunnel experiments or field measurements. Collaborate with interdisciplinary teams to incorporate wind effects into risk models, design standards, and resilience strategies. Publish and present research in peer-reviewed journals and at scientific or industry conferences. Contribute to strategic planning and innovation in wind engineering research initiatives. PhD degree. Mechanical, Civil, Aerospace Engineering or related fields. Hands-on experience with CFD software, both open-source (e.g., OpenFOAM) and commercial (e.g., ANSYS Fluent). Proficient in programming languages such as C++, Python, R, MATLAB. Skilled in high-performance computing (HPC) and parallel computing environments. Experience with wind tunnel testing or field measurements is highly desirable. Familiarity with relevant building codes and standards is a plus. Proven track record of publishing high-quality research and effectively communicating complex technical concepts to diverse audiences.Strong problem-solving abilities, creativity, and the capacity to work independently as well as collaboratively. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce.

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients. Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits. Today, Strand has established multiple programmable mRNA platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a Phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts. Become the next standout single strand! Job Summary: Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company. We are looking for a highly motivated and innovative candidate for the role of Scientist of LNP Discovery. The expectation is that the candidate will have experience in the world of LNP discovery research particularly focused on the successful delivery of nucleic acid payloads. Reporting to the Principal Scientist of LNP Discovery, the right candidate will be a strategic thinker that brings a leadership presence and enthusiasm for Strand along with a deep scientific knowledge. Primary Responsibilities: Help advance Strand's mRNA delivery platform and capabilities. Lead and contribute to lipid innovation and development/optimization of lipid nanoparticle (LNP) formulations. Characterize the physicochemical properties and evaluate therapeutic indices of (lipid) nanoparticle formulations using standard or newly developed in-house assays. Execute LNP composition optimization and screening assays. Produce (lipid) nanoparticle formulations to support internal and partnered programs. Compile data reports and communicate the results with relevant team(s). Research and identify new opportunities and novel project ideas related to mRNA delivery that support Strand's vision. Maintain and establish new relationships with outside collaborators which provide access to proprietary (lipid) nanoparticles. Write study protocols, technical reports and SOPs that support the drug discovery efforts of Strand. Interact with IP counsel/consultants to assist with patent prosecution. Qualifications: B.S. or Advanced Degree with 6-7+ years of industry experience with a focus on lipid chemistry, nanoparticle formulation and in vivo delivery of nucleic acid-based payloads. Experience with lipid chemistry required. Experience with production and analytical characterization of (lipid) nanoparticles required. Prior experience with (high throughput) screenings of (lipid) nanoparticles preferred. Prior experience with development of tissue/cell targeting (lipid) nanoparticles would be a plus. Excellent knowledge of the scientific literature in the field of mRNA delivery. Demonstrated experience working across internal and external research teams. Highly analytical, decisive, and goal-oriented while maintaining the highest scientific and ethical standards. Ability to quickly adapt to change and thrive in a dynamic and entrepreneurial early-stage environment. A strong team player with excellent oral and written communication skills and a demonstrated ability to work independently. Strand offers a fast-paced, entrepreneurial, team-focused small company environment. We also offer a top-notch benefits package (health, dental, life, open PTO, onsite lunch catering, commuter support and more) and work/life flexibility and integration. Being part of the Strand team allows you to become part of a small team that supports professional development while working together to meet Strand's goals. Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates. Job Type: Full-time Salary: $100,000 - $140,000 annually plus bonus and equity incentives Pay Transparency Base Salary Range $100,000 - $140,000 USD

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Expedition Medicines Inc., is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic modalities. Our platform integrates novel small molecule chemistry and chemoproteomic discovery technologies with Machine Learning (ML) to enable generative design. Expedition Medicines is backed by Flagship Pioneering, bringing their courage, vision, and resources to guide Expedition Medicines from platform validation to patient impact. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us! THE ROLE The Formulation team is seeking a highly motivated, attentive and self-driven candidate to join our team and contribute to the development of discovery compounds as an Senior Research Associate/Associate Scientist. This successful candidate will join an energizing and collaborative research environment working as part of cross function drug discovery teams in providing a develop-ability assessment of innovative molecules. KEY RESPONSIBILITIES Execute stage appropriate, fit-for-purpose preclinical formulations preparation (Solutions, suspensions, emulsions, nanoparticles, SEDDS etc.) for oral, and parenteral formulations on a small scale for small molecules Author protocols describing preparation of formulations for use at internal and external formulation labs Basic drug substance characterization by using techniques such as HPLC/UPLC, XRPD, DSC and PLM. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability Routine lab support such as buffer and mobile phase preparation, pH meter calibration, basic troubleshooting of lab equipment, and coordinating with external instrument and service vendors. Shipping and receiving samples between internal and external sites Summarize experimental results and presents at team meetings and department presentations Author templated memos and reports with limited guidance Maintain detailed lab notebooks and reports in compliance with GLP/GMP guidelines (as applicable) Evaluate novel drug delivery systems (e.g., lipid-based, amorphous solid dispersions, spray dry etc.) for poorly soluble compounds Support transition of formulations from discovery to clinical development (e.g., bridging studies) Independently design and perform focused experiments that drive progress in cross-functional formulation initiatives PROFESSIONAL EXPERIENCE & QUALIFICATIONS B.S. or M.S. in Chemistry, Biochemistry, Chemical Engineering, or a related discipline is required Three years minimum of industry, government or equivalent experience in small molecules formulation or a related field Hands-on experience with one or more of the following techniques: HPLC, UV-visible, DSC etc Experience with data analysis using standard software platforms (Excel, Prism etc.) Practical experience in developing and preparing preclinical formulations (small molecules) Basic knowledge of physicochemical properties and their relationship to formulation development Basic knowledge of pharmacokinetics (PK) and biopharmaceutics principles The ability to manage multiple parallel activities and deliver results to agreed timelines Ability to do bench work independently Strong collaboration, problem-solving, and adaptability in fast-paced research environments Excellent written, oral, and visual communication skills Excellent time management skills LOCATION: Cambridge, MA ABOUT FLAGSHIP PIONEERING Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at *************************** At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship. Recruitment & Staffing Agencies : Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. #LI-MB1 The salary range for this role is $81,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicine's good faith estimate as of the date of publication and may be modified in the future.

SES AI Corp. (NYSE: SES) is dedicated to accelerating the world's energy transition through groundbreaking material discovery and advanced battery management. We are at the forefront of revolutionizing battery creation, pioneering the integration of cutting-edge machine learning into our research and development. Our AI-enhanced, high-energy-density and high-power-density Li-Metal and Li-ion batteries are unique; they are the first in the world to utilize electrolyte materials discovered by AI. This powerful combination of "AI for science" and material engineering enables batteries that can be used across various applications, including transportation (land and air), energy storage, robotics, and drones. To learn more about us, please visit: ********** What We Offer: A highly competitive salary and robust benefits package, including comprehensive health coverage and an attractive equity/stock options program within our NYSE-listed company. The opportunity to contribute directly to a meaningful scientific project-accelerating the global energy transition-with a clear and broad public impact. Work in a dynamic, collaborative, and innovative environment at the intersection of AI and material science, driving the next generation of battery technology. Significant opportunities for professional growth and career development as you work alongside leading experts in AI, R&D, and engineering. Access to state-of-the-art facilities and proprietary technologies are used to discover and deploy AI-enhanced battery solutions. What we Need: The SES AI Prometheus team is seeking an exceptional Scientist, Molecular AI Architecture to pioneer the convergence of biological computation, large-scale multimodal foundation models, and explainable AI architectures. This visionary role will drive next-generation materials discovery by developing novel AI systems. Essential Duties and Responsibilities: AI Architecture & Design: Architect novel AI systems and deep neural architectures (e.g., Transformers, CNNs) inspired by principles of systems neuroscience and neural coding principles. Design and implement large-scale multimodal foundation models and agentic AI systems capable of complex reasoning over molecular and battery datasets. Develop methods for model interpretability, representation engineering, and causal reasoning to ensure AI results are explainable and trustworthy for materials science. High-Performance Computing & Efficiency Lead software development efforts for high-performance computing (HPC), focusing heavily on GPU programming and scaling the training and inference efficiency of large neural networks. Optimize complex ML frameworks (like JAX) within systems and cluster computing environments (e.g., Singularity). Scientific ML Integration Create automated data-labeling and behavioral encoding models specifically designed to enhance Molecular AI training and data efficiency. Apply Scientific ML principles to complex molecular and battery datasets, translating biological computation concepts into practical AI solutions for materials discovery. Education and/or Experience: Education: Ph.D. in Computational and Systems Biology, Computational Neuroscience, or a closely related quantitative field. Core Expertise: Deep, demonstrated expertise in systems neuroscience, machine learning, and the design and implementation of deep neural architecture. HPC Software: Proven experience with software development for High-Performance Computing (HPC) environments, including expert-level GPU programming. Model Design: Practical experience in designing and training foundation models and working with concepts like multi-agent reasoning models. Interpretability Focus: Demonstrated work in model interpretability and representation engineering applied to complex scientific data. Preferred Qualifications: Specialized Frameworks: Practical experience with advanced mathematical and machine learning frameworks like JAX and Julia. Advanced Techniques: Expertise in Bayesian inference and working within specialized container/computing environments like Singularity. Advanced AI: Experience with the design and application of agentic AI systems and multimodal reasoning architectures.

Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D FLSA Status: Exempt Salary: $100,000-$160,0000 Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ****************** About the Role The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes. Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities. Key Responsibilities Perform hands-on small molecule process development and scale-up work. Use Design of Experiments (DoE) for process screening, optimization, and robustness studies. Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies. Apply process analytical technology (PAT) and process modeling. Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance. Conduct independent research to achieve mechanistic understanding for rational process design. Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction. Use process modeling tools to inform scale-up strategies. Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing. Drive cycle time reduction and process intensification initiatives. Implement innovative technologies such as continuous flow chemistry and automation platforms. Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments. Support development of complex transformations such as catalytic hydrogenation. Exhibit a mindset of safety and quality compliance. Collaborate cross-functionally within US, UK, and China-based teams. Required Experience & Skills Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense. Experience performing lab-based research/process development in a chemical engineering-related area. Experience with organic chemical synthesis and wet chemistry. Experience with small molecule pharmaceutical drug substance development. Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling. A high level of innovation, creativity, and self-initiative. Highly effective communication and collaboration skills. Good organizational, interpersonal, writing, and time management skills. Preferred Experience & Skills Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale. Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production. Demonstrated experience with chemical engineering-related technology development. Familiarity with kilo-scale laboratory equipment. Experience with process modeling (e.g., population balance modeling, distillation modeling). Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills). Why Pharmaron? Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

ABOUT US There are more than 9 million immunocompromised people in the United States. Almost half a million of those represent a population that are moderately to severely immunocompromised and at highest risk for severe COVID-19, including stem cell and solid organ transplant patients as well as those with hematologic cancers. At Invivyd, Inc., we take those numbers very seriously and we come to work each day on a mission to deliver protection from serious viral infectious diseases, beginning with SARS-CoV-2. Invivyd deploys a proprietary integrated technology platform unique in the industry designed to assess, monitor, develop, and adapt to create best in class antibodies. In March 2024, Invivyd received emergency use authorization (EUA) from the U.S. FDA for a monoclonal antibody (mAb) in its pipeline of innovative antibody candidates. In October 2025, the FDA cleared the company's Investigational New Drug (IND) application and provided feedback to advance the company's REVOLUTION clinical program, Invivyd's development program for VYD2311, a vaccine alternative monoclonal antibody being investigated for the prevention of COVID-19. Be part of making a difference. Be part of Invivyd. Location: Newton, MA Invivyd's lab is in Newton, MA. This role will be an in-person role. Position Summary: In this role you will design, develop and execute functional assays for a cutting-edge antibody discovery platform. This involves applying a breadth of techniques in the virology, molecular biology, cell biology, and immunology spaces to advance innovative biotherapeutic products through discovery and pre-clinical development stages at Invivyd. This is a unique opportunity to join Invivyd's Antibody Discovery and Preclinical Development Team which generates and characterizes human therapeutic antibody candidates against infectious disease targets like SARS-CoV-2, influenza, and RSV. The Assay Development Senior Research Associate will serve as a key member of the discovery team, provide expert input, and execute new and established methods to meet project requirements and timelines. Responsibilities: * Development and independent troubleshooting of virus-based antibody screening functional assays and optimization of existing assays. * Contribute to high-impact projects within the Discovery group by characterizing lead antibody molecules for pre-clinical studies. * Design and perform experiments involving in vitro screening and characterization of antibody drug candidates using immunological, biochemical, and cell-based assays. * Design and generate pseudoviruses for use in evaluation of antibody candidates. * Generate authentic viruses in a BSL-2 setting for use in evaluation of antibody candidates. * Perform molecular design and characterization of DNA constructs used for assay development. * Execute basic molecular biology (DNA/RNA extraction, RT-PCR, PCR, cloning, etc.) and Cell Biology (mammalian cell culture, gene transfection and expression) to support antibody discovery efforts. * Collaborate closely across an interdisciplinary biologics research team to drive antibody discovery campaigns. * Employ high-throughput molecular biology methods for building new vectors and libraries. * Maintain appropriate records e.g. lab notebook, protocols, reports, data integrity. * Present data, both orally and as written reports, to internal stakeholders. Requirements: * Master's degree or Bachelor's degree and 6+ years of bench Industry experience in virology, molecular biology, cell biology, or other life science disciplines. * High proficiency in mammalian cell culture is required. * Previous experience working with virus in a BSL-2 setting is required. * Previous experience designing and optimizing cell-based assays and functional antibody characterization is highly preferred. * Ability to interpret in-process readouts for the purposes of assay optimization and troubleshooting. * Mammalian cell transfection with an understanding of expression vector design is highly preferred. * Strong understanding of molecular biology and experience with DNA construct design and sequence analysis is highly preferred. * Proactive team player and flexibility to work on multiple projects as the discovery programs evolve over time. * Excellent verbal and written technical and non-technical communication skills. At Invivyd we strive to create a welcoming and inclusive environment. Here all applicants will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. Invivyd is proud to be an equal opportunity employer. We do not accept unsolicited resumes from agencies.

General information Location Cambridge, MA Ref # 43395 Job Family Research Date published 12/09/2025 Time Type Full time Pay Range 100,000 - 140,000 Usd Annual Description & Requirements The Broad Institute of MIT and Harvard is the world's leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. We seek to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community. We are seeking a highly motivated and innovative scientist to lead collaborative initiatives in partnership with the Cancer Dependency Map and Cancer Cell Line Factory programs and the Sellers and Getz labs at the Broad Institute. The primary goal of this role is to develop advanced laboratory cellular models to enable functional genomics, drug screening, and drug resistance studies. Our current focus is on deriving 3D models for pediatric and rare cancers, with an initial pilot to generate cancer-resistant cell lines for major oncology drugs. This work will lay the foundation for expanding cancer cell line diversity through additional grant funding and external collaborations. The ideal candidate will be a proactive, curious scientist with a strong background in cell biology, patient-derived cancer models, drug resistance research, and platform development. This position also offers the opportunity to build leadership skills while working closely with Senior Group Leaders. Qualified candidates should have: A Ph.D.in a biological science (such as cell biology, biochemistry, cancer biology, or a related field) and a completed or soon-to-be-completed postdoctoral fellowship in a similar field. 2+ years of experience as a postdoc or in the industry. Excellent organizational and time management skills with strong attention to detail. Experience in cell biology with a focus on method development, team management, and mentoring junior research associates is highly desirable. Required Skills: Self-motivated and curious, with the ability to lead scientific research effectively. Demonstrated excellent problem-solving and communication skills with leadership, colleagues, and junior research associates. Track record of independently delivering scientific results. Expertise in molecular and cell biology techniques, including flow cytometry, immunofluorescence staining, Western blotting, ELISA, HTS cell culturing, 3D cell culturing, drug testing, etc. Impeccable and efficient experimental design, assay development, and execution. Strong commitment to "leading from the bench". Excellent interpersonal, written, and oral communication skills, perform detailed data analysis, and accurate record-keeping to support the cell model team members. Extensive experience in following and improving assay protocols is preferred. Responsibilities: Lead experimental design for cell model development, implement newly developed protocols, and conduct proof-of-concept studies to evaluate feasibility and optimize workflows. Serve as the technical lead and subject matter expert for cell model development efforts, driving strategic improvements to enhance efficiency, success rates, and overall platform capabilities. Validate cell models through sequencing technologies and oversee model fidelity assessments using flow cytometry, immunofluorescence, western blotting, and other relevant assays in collaboration with internal Scientists and Research Associates. Lead drug resistance modeling projects to establish oncology drug-resistant clones for functional genomics analyses. Manage and mentor Research Associates, fostering scientific and professional growth while ensuring high-quality data generation. Collaborate with Sellers Lab, Getz Lab, Cancer Dependency Map, PRISM drug screening, Cancer Genomics, and Cancer Data Sciences teams to advance research initiatives and share expertise. Coordinate closely with cancer genomics core staff to integrate experimental data with genomic insights for comprehensive analysis and interpretation. Identify opportunities for platform innovation and expansion to address emerging scientific needs and challenges. Partner with internal teams on large-molecule discovery and validation efforts to support broader oncology research goals. The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact ***************************** for assistance.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. We serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world's greatest health challenges. At the Lilly Innovation Center in Boston, Massachusetts, we explore how next generation therapeutics, new technologies, data analytics and new care models can improve patient health and the healthcare system. Our Genetic Medicine team in Boston shares a passion for challenging conventional wisdom and creating an environment that embraces creative, break-through concepts. The Center offers a start-up environment with large company support. It is located in the heart of Massachusetts' exploding science and technology cluster and is within walking distance of some of the best academic and industry innovators in the world. The successful candidate will have a strong research track record in synthetic organic chemistry/chemical biology/biotechnology and be analytically minded, systematic, and embrace data-driven decision making. The scientist will collaborate with multidisciplinary teams across key Lilly therapeutic areas (e.g. neuroscience, diabetes, immunology) to perform synthesis and related experiments to aid development of RNA oligonucleotide drug candidates for the next generation of RNA therapies. Key responsibilities include: Perform synthesis and chromatographic purification of innovative phosphoramidite monomers, and carry out conjugation of novel ligands-such as small molecules and peptides-to oligonucleotides for targeted delivery. Design and execution of automated workflows for synthesizing, purifying, and analyzing ASOs, si RNAs, SSOs, and related oligonucleotides across various chemistries and scales using advanced instrumentation platforms. Apply analytical techniques including UV-Vis spectroscopy, NMR, HPLC, and LC-MS to evaluate both crude and purified synthetic compounds. Interpret and organize analytical data and research outcomes for presentation to project teams. Support resolution of technical issues and contribute scientific and technical insights to ongoing projects. Provide strategic input into experimental planning, integrated data analysis, and effective communication of results to scientific teams and leadership. Maintain meticulous records of experimental procedures and key steps to ensure reproducibility, including accurate documentation in electronic lab notebooks in accordance with Lilly's quality standards. Assist with general lab operations such as ordering supplies, preparing reagents, and maintaining equipment. Collaborate closely with colleagues across multiple sub-teams within the Lilly LGM group. Adhere strictly to all health and safety protocols. Demonstrate a strong commitment to fostering a diverse and inclusive laboratory environment every day. Basic Qualifications: Bachelor's or Master's Degree in chemistry, biochemistry, pharmacology, or related scientific field 1+ years of work experience in an academic laboratory, or preferably in an industrial setting Additional Skills/Preferences: Demonstrated expertise in organic synthesis and advanced chromatographic purification techniques is essential. Prior experience with the synthetic manipulation of nucleosides, nucleotides, phosphoramidites is highly desirable. Hands-on experience in conjugation and bioconjugation chemistry; familiarity with solid-phase synthesis methods for oligonucleotides or peptides is a plus. Proven laboratory proficiency with analytical instruments such as HPLC and LC-MS, including the ability to analyze, interpret, and effectively communicate data. Adaptable and highly motivated to thrive in a dynamic, fast-paced research environment. Strong communication skills and a collaborative mindset, with the ability to work efficiently across interdisciplinary teams. Exceptional organizational abilities, attention to detail, and critical thinking skills; capable of multitasking and eager to learn new methodologies and contribute to innovation. Skilled in processing, structuring, analyzing, and visualizing data from diverse sources, with the ability to derive meaningful insights. Proficient in Microsoft Excel, Word, PowerPoint, and analytical software relevant to experimental methods. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $69,000 - $179,300 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

About Somite Somite.ai is a venture-backed company aiming to become the OpenAI of stem cell biology, developing AI foundation models for human stem cells to drive novel cell therapies at scale. We take a full-stack approach - generating data at 1,000x lower cost, training large-scale models with unmatched predictive power, and using these models to discover, refine, and optimize high-impact applications in cell therapy. Our founding team includes repeat AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT (pioneered the foundational research on scaling laws), and three Harvard Medical School professors and National Academy of Sciences/Medicine members, including the Chair of the Genetics Department at HMS. Based in Boston and launching operations in January 2024, Somite has raised close to $60M to date (Forbes). Somite's Core Values: We show up - fully accountable, all-in, doing whatever it takes We act with urgency - swift, decisive, proactive We support one another - collaborative, helpful, empathetic Location: Boston, MA (onsite, full-time) About the Role: We seek a skilled Bioinformatician to lead the design and execution of analysis pipelines for large-scale transcriptomic datasets. You'll be responsible for preprocessing, quality control, and biological interpretation of sequencing data, contributing to the development of novel sequencing protocols and technologies in close collaboration with wet lab scientists, computational biologists and machine learning researchers to support Somite's therapeutic programs. This is a hands-on, data-centric role ideal for someone who thrives in a fast-paced, interdisciplinary environment and wants to help build transformative cell therapy technologies from the ground up. Responsibilities: Build, maintain, and run robust, reproducible pipelines for single-cell and bulk RNA-seq data (QC, alignment, quantification, normalization, clustering, annotation, etc.). Apply standard and advanced analyses using tools like Scanpy, Seurat, and R/Bioconductor packages. Process and interpret data from state-of-the-art single-cell transcriptomic and multiomic platforms, alongside new in-house protocols being developed to enable innovative microbiological sequencing workflows. Collaborate with wet lab scientists to support experimental design and data interpretation. Mentor and foster collaboration and knowledge sharing across disciplines. Help design and validate cutting-edge protocols for novel transcriptomic technologies, integrating new experimental modalities with bioinformatics pipeline. Qualifications: PhD in Bioinformatics, Genomics, Computational Biology, or a related field. Equivalent industry experience is also welcome 3+ years of hands-on experience analyzing large-scale single-cell or bulk transcriptomic datasets Proficiency with common genomics tools: SAMtools, STAR/STARsolo, Bowtie, Tophat, HTSeq, Clustal, bash scripting, etc. Strong command of Scanpy or Seurat Demonstrated fluency in Nextflow/Snakemake and workflow reproducibility principles. Strong R and/or Python programming skills Excellent organizational and documentation habits Preferred Qualifications: Experience working in a quantitative lab or with biotech/pharma pipelines Experience working in a fast-paced startup or interdisciplinary team The opportunity to contribute to platform technologies with real-world therapeutic impact Experience working at the interface of technology development and data analysis, particularly involving novel molecular biology or sequencing techniques What We Offer A mission-driven team reshaping healthcare through innovation in AI and cellular engineering. The opportunity to contribute to platform technologies with real-world therapeutic impact. Competitive compensation and equity in a high-growth company. Flexible work arrangements, generous benefits, and a collaborative environment. Exceptional candidates who demonstrate outstanding capabilities and potential will be considered, even if they do not meet every qualification listed. Join us and help unlock the full potential of AI for the benefit of human health!

Artech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution phases, and provide budgeting/financial flexibility by offering contingent labor as a variable cost. Job Description: Primary Responsibilities: •Assist Lead Biomarker Scientist to develop, optimize, validate, and perform FACS-based and other biomarker assays to support studies in New Haven CRU and external protocols if needed. •Perform general flow cytometry operation, including sample preparation and analysis. Experience in FACSCanto Flow Cytometer and FACSDiva software. •Perform quality control checks on Flow Cytometers and other Laboratory instruments, reagents, and techniques. •Operate, maintain, calibrate and trouble shoot Flow cytometers and other Laboratory instruments according to SOPs. •Maintain quality control and calibration logs of all Flow Cytometers. •Analyze, summarize and document experimental results. •Perform data entry using laboratory information management system (LIMS) •Write experimental SOPs. •Update Biomarker Lead on the status, results and problems in method development and performance of the assays. •Complete all NHCRU/Pharmaceutical required training. •Have a working knowledge of Microsoft office including Excel, Word and PowerPoint. •Possess multi-tasking and organizational skills. •Experience in ELISpot Assays and FlowJo software a plus. Qualifications: Minimum of either MS in Biology/BioChemistry/Medical Technology plus 1 year of relevant experience BS in Biology/BioChemistry/Medical Technology or 3 years of relevant experience. Additional Information Best Regards, Anuj Mehta ************

The Belfer Center for Applied Cancer Science is an integrative research center within Dana-Farber Cancer Institute. Our mission is to enhance and accelerate oncology drug discovery & development through bridging of academia, industry, and clinical research. We apply industrial capabilities to cutting edge academic/clinical science. We partner with industry in drug discovery/development & work with industrial partners to delineate the clinical path of novel therapies for cancer patients. This integrated, goal-oriented organization represents a new academic construct that provides an unprecedented opportunity to change the way anti-cancer therapeutics are discovered and developed. For more information please visit: ************************************* Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. + Lead multi-laboratory collaborations to characterize novel targets and therapeutic approaches for cancer + Design experiments and execute on protocols; propose modification to protocols as needed + Maintain accurate records, write reports, and prepare presentations + Contribute to project team as well as overall laboratory organization and safety + Operation and maintenance of mass spectrometer instrumentation + Manage project Team + Ph.D. in mass spectrometry or related field with 4-5 years experience + Experience working in proteomics and biochemistry + Experience performing quantitative mass spectrometry assays + Familiarity with Thermo instrumentation (Eclipse, Fusion, Q Exactive Plus, EASY-nLC, Astral-Orbitrap) + Familiarity with mass spectrometry methods (DIA, DDA, TMT-MS3, MRM, PRM, Intact Mass, etc.) + Independent, self-motivated, and innovative + Excellent written and oral communication skills + Outstanding interpersonal and team skills + Ability to excel in a goal-oriented and fast-moving team environment + Basic immunology a plus **Pay Transparency Statement** The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA) $74,600 - $82,900 At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. **EEOC Poster**

We are seeking a highly motivated and innovative Scientist to support the discovery and development of gene therapies for rare genetic diseases. The candidate is expected to have proven practical technical capability and experience in, cell culture and cell based assays, protein purification and analytical assays. She/he should be scientifically motivated and capable of critically analyzing and interpreting data and reporting experimental results. Strong presentation and communication skills and the ability to work in a fast-paced and team-oriented environment will be vital. The position will support the development of a pipeline of gene therapy - associated product concepts while working in a cross- functional and collaborative environment Skills: • Experience with mammalian cell culturing techniques and cell based assays. • Experience with PCR, qPCR, Southern / Western blotting, Experience with FPLC / HPLC systems. • Ability to work in a team orientated, collaborative environment Strong communication and presentation skills • Prior experience with production and purification of AAV vectors is a plus Keywords: Education: BS/MS with a minimum of 8 years of related experience Qualifications BS/MS with a minimum of 8 years of related experience

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham. We're offering a generous sign-on bonus of $10,000 to eligible candidates who join our team. Recognizing and valuing exceptional talent, we're excited to discuss the details of this bonus during the interview process. Job Summary Summary As required by CLIA, testing personnel are responsible for specimen processing, test performance, and reporting test results. Each individual performs only those tests authorized by the laboratory director and requiring a level of skill appropriate to their education, training, experience, and technical abilities. The role requires working independently in an efficient and organized manner to ensure accurate results and documentation. This position requires professional-level knowledge to accurately read and interpret test results used by providers in diagnosing and treating diseases. The Medical Laboratory Scientist, Senior I, in their role as Technical Supervisor, Technical Consultant, or General Supervisor as defined by CLIA, may be delegated responsibility for technical oversight of the laboratory, including day-to-day supervision of operations and personnel performing testing and reporting results. Under the general supervision of the Technical Director and Clinical Supervisors, the Senior Technologist I also oversees assigned workstations, including Quality Control (QC) review, staff training, competency assessments, and inventory management. Does this position require patient care? No Essential Functions After successful completion of orientation, training, and competency assessment on all applicable instruments and methods, the Senior Technologist I must: Follow the laboratory's procedures for specimen handling and processing, test analyses, reporting, and recordkeeping. Maintain records demonstrating that proficiency testing samples are analyzed in the same manner as patient samples. Adhere to quality control policies and document all QC activities, calibrations, and maintenance. Follow established corrective action procedures when test systems fall outside acceptable performance standards. Identify issues that may adversely affect test performance or result reporting, and either correct them or immediately notify the appropriate supervisor or director. Document all corrective actions taken when test systems deviate from established performance specifications, in accordance with 42 CFR 493.1425 and 493.1495. Qualifications Education Bachelor's Degree Clinical Laboratory Sciences required or Bachelor's Degree Medical Technology required or Bachelor's Degree Laboratory Sciences required and Can this role accept experience in lieu of a degree? No Licenses and Credentials Medical Technologist (ASCP) [MLT, MT, MLA, Histologists] - American Society for Clinical Pathology Board of Certification (ASCP-BOC) required Experience lab experience 4 years required Knowledge, Skills and Abilities * The knowledge, both practical and theoretical, of tests and procedures necessary to review findings and advise and direct subordinates in action. * Demonstrates advanced level of analytical skills and judgement. * Must have understanding of computer technology and its application to analytical procedures and quality control. * Must have a comprehensive understanding of laboratory equipment and its operation, maintenance, and repair, and analytic techniques. * Must have the ability to work independently, evaluate situations and act appropriately. * Ability to multitask in a fast-paced environment. * Must have the ability to pay careful attention to detail and to adhere to written protocols, including communication with supervisors when issues are identified. * Must be able to perform as a team member. * Excellent interpersonal skills. * Ability to interact professionally and effectively with numerous staff including physicians, hospital personnel, employees, and patients. * Advanced knowledge of federal, state and accreditation requirements. Additional Job Details (if applicable) Physical RequirementsStanding Frequently (34-66%) Walking Frequently (34-66%) Sitting Occasionally (3-33%) Lifting Frequently (34-66%) 35lbs+ (w/assisted device) Carrying Frequently (34-66%) 20lbs - 35lbs Pushing Occasionally (3-33%) Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing Frequently (34-66%) Stooping Occasionally (3-33%) Kneeling Occasionally (3-33%) Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%) Reaching Frequently (34-66%) Gross Manipulation (Handling) Frequently (34-66%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision - Far Constantly (67-100%) Vision - Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%) Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America) Pay Range $33.46 - $48.66/Hourly Grade 7 At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package. EEO Statement: The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at **************. Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

The University of Connecticut Proteomics and Metabolomics Facility (UConn PMF, ***************************** is hiring a Facilities Scientist 2 to assist the Facility Director with quantitative proteomics analysis using advanced mass spectrometry instrumentation and leading bioinformatics software. The PMF opened in 2017 as the University of Connecticut's first proteomics-focused and full service mass spectrometry core facility, and is housed administratively within the Center for Open Research Resources and Equipment (************************ UConn PMF in Storrs has outstanding instrumentation (2 Waters TOFs, 2 Thermo Scientific Orbitraps, and a Bruker tims TOF HT) and is expanding its footprint to the UConn Health medical research campus (Farmington, CT) in Summer 2025 with a brand new Bruker tims TOF Ultra 2 mass spectrometer. UConn PMF exists to provide fully customized analysis to more than 200 faculty across multiple UConn campuses and at other regional academic and industry research institutions. This position will be a full-time appointment and will provide a unique opportunity to work in a rapidly growing and highly productive core facility at a large research university currently ranked in the top 25 of all public universities in the U.S. MINIMUM QUALIFICATIONS * Master's degree in chemistry, biochemistry, analytical chemistry, or related field with at least 3 years of experience, OR Ph.D. degree in a similarly relevant field, with demonstrated experience implementing high resolution mass spectrometry for the analysis of proteins and peptides, and familiarity with operation, maintaining, and troubleshooting high resolution mass spectrometer and nanoflow ultra-high performance liquid chromatography systems. * Publication history that demonstrates successful application of state-of-the-art mass spectrometry for label-free and/or label-based (e.g. Tandem Mass Tags, iTRAQ, SILAC) quantitative proteomics. * Demonstrated experience using common proteomics software platforms for peptide/protein identification and quantification such as Spectronaut, MaxQuant/Andromeda, Proteome Discoverer, Byonic, and/or Scaffold Q+S. * Demonstrated mastery of sample preparation techniques for downstream proteomics analysis such as in-gel/in-solution digestions, co-immunoprecipitations, and processing of whole cell lysates or tissue homogenates for bottom-up proteomics. * Demonstrated clear and effective communication skills while communicating with researchers of varied scientific backgrounds, specifically regarding analytical techniques and informatics methods. * Experience working in a highly collaborative environment that emphasizes comprehensive analysis and one-on-one consultations with researchers. PREFERRED QUALIFICATIONS * Experience with extensive collaborative projects or experience in a core facility setting. * Experience using Bruker tims TOF instrumentation for low input proteomic analysis utilizing DDA-PASEF and DIA-PASEF acquisition methods. * Experience with untargeted metabolomics workflows, including sample preparation and analysis using TOF instrumentation and small molecule identification using Progenesis QI, XCMS, and/or other programs. APPOINTMENT TERMS This is a full-time, 12-month, non-tenure-track position with an anticipated start date in September 2025. Salary will be commensurate with qualifications and experience. Other rights, terms, and conditions of employment are contained in the collective bargaining agreement between the University of Connecticut and the American Association of University Professors UConn Chapter (AAUP). The University offers a competitive salary, and outstanding benefits, including employee and dependent tuition waivers at UConn, and a highly desirable work environment. For additional information regarding benefits, please visit hr.uconn.edu and explore the sections under the Benefits & Leaves and Engagement & Learning headers. TERMS AND CONDITIONS OF EMPLOYMENT Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check. TO APPLY Please apply online at ************************** Faculty and Staff Positions, Search #499108 and submit the following application materials: resume, cover letter, and contact information for three (3) professional references. Questions regarding this search should be addressed to Dr. Jeremy Balsbaugh, Director of COR²E and PMF (**************************). This job posting is scheduled to be removed at 11:55 p.m. Eastern time on December 17, 2025. All employees are subject to adherence to the State Code of Ethics which may be found at ****************************************** All members of the University of Connecticut are expected to exhibit appreciation of, and contribute to, an inclusive, respectful, and diverse environment for the University community. The University of Connecticut aspires to create a community built on collaboration and belonging and has actively sought to create an inclusive culture within the workforce. The success of the University is dependent on the willingness of our diverse employee and student populations to share their rich perspectives and backgrounds in a respectful manner. This makes it essential for each member of our community to feel secure and welcomed and to thoroughly understand and believe that their ideas are respected by all. We strongly respect each individual employee's unique experiences and perspectives and encourage all members of the community to do the same. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. The University of Connecticut is an AA/EEO Employer.

Senior Materials Scientist - Battery Materials & Computational Design We are hiring a Senior Materials Scientist with deep expertise across next-generation battery materials, computational modeling, and AI-driven materials design. This role sits at the intersection of chemistry, physics, and machine intelligence-driving the discovery and validation of novel materials for high-performance energy systems. Key Responsibilities Lead end-to-end battery material development: raw-material chemistry, electrode fabrication, and electrochemical testing. Build and refine computational models for molecular property prediction, multi-physics simulation, and materials screening. Apply AI/ML techniques to accelerate material selection, structure-property prediction, and generative chemistry workflows. Design experiments, validate computational predictions, and iterate material performance through lab-based testing. Collaborate with cross-functional teams across materials, chemistry, modeling, and hardware engineering. Core Requirements PhD in Mechanical Engineering, Aerospace Engineering, Materials Science, Chemical Engineering, Applied Physics, or related field. Proven experience in battery material R&D, solid-state systems, or advanced electrode technologies. Strong background in computational modeling (DFT, molecular modeling, multi-physics simulations). Hands-on experimental validation expertise with electrochemical characterization and material testing. Knowledge of AI/ML model development for materials informatics, property prediction, or generative chemistry.

Established nearly two centuries ago, FM is a leading mutual insurance company whose capital, scientific research capability and engineering expertise are solely dedicated to property risk management and the resilience of its policyholder-owners. These owners, who share the belief that the majority of property loss is preventable, represent many of the world's largest organizations, including one of every four Fortune 500 companies. They work with FM to better understand the hazards that can impact their business continuity to make cost-effective risk management decisions, combining property loss prevention with insurance protection. The purpose of this position is to develop new scientific knowledge, technologies and engineering solutions to problems in material flammability, fire dynamics and Lithium-ion battery safety research, which can be used for the prevention or control of industrial property loss. The principal responsibilities are to carry out research projects in the areas of flammability, fire spread, and heat transfer in fires from solid combustible as well as Lithium-ion batteries. Key areas of research include understanding of fire behavior at the medium and large scales via bench-scale experiments and theoretical models on material flammability and flame heat transfer. Projects can also involve advanced flame diagnostic of buoyant turbulent sooty flames and wall fires. The experimental and theoretical studies will be closely integrated with Computational Fluid Dynamic (CFD) model development and validation within the work group. The position is responsible for all aspects of project management including project proposals, execution, and reporting. The position requires a PhD in Mechanical, Chemical Engineering, Fire Protection Engineering, or related fields with a strong fundamental background in combustion, fluid mechanics, heat transfer, material science and applied mathematics. Extensive experience in experimental methods in thermal fluids, material flammability, heat transfer, combustion/fire, and an understanding of associated numerical methods are required. Research experience with advanced laser diagnostics in flame, experimental measurement in turbulent flame, heat transfer and failure analysis of battery is desirable. Also needed are excellent written and verbal communication skills, as well as demonstrated expertise in developing solutions to challenging technical problems. The final salary offer will vary based on geographic location, individual education, skills, and experience. The position is eligible to participate in FM's comprehensive Total Rewards program that includes an incentive plan, generous health and well-being programs, a 401(k) and pension plan, career development opportunities, tuition reimbursement, flexible work, time off allowances and much more. FM is an Equal Opportunity Employer and is committed to attracting, developing, and retaining a diverse workforce. #FMG #LI-TA1

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing, and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. The LIGM RNA Group is seeking an experienced analytical scientist with extensive hands-on experience in analytical techniques for characterizing and analyzing small molecules, biologics, and/or oligonucleotides. The ideal candidate will have a proven track record in analytical method development and troubleshooting, as well as experience with liquid chromatography, (high resolution) mass spectrometry, and other advanced analytical techniques. They must possess strong technical problem-solving skills, be computer savvy with the ability to navigate multiple instrument control programs and data analysis environments, and be able to work independently to achieve efficient, quality results in a fast-paced environment. Responsibilities: Work closely with the chemistry team to source, explore, and implement the latest separation science and analytical technologies for the purification and characterization of oligonucleotides and their conjugates, including carbohydrates, lipids, peptides, and proteins. Conduct LC and LC-MS based method development for sensitive characterization of biologics including intact mass, reduced mass, peptide mapping, and glycan mapping to provide better understanding of attributes. Conduct semi-preparative and preparative method development activities to advance downstream processing for challenging modified oligonucleotides, utilizing RP purification, ion-exchange chromatography, spin filtration, TFF, FPLC, size exclusion chromatography, and MS-direct auto-scale preparative LC-MS techniques. Work with contractors and third-party vendors to troubleshoot and maintain lab instruments, including but not limited to UPLC, LC-MS, osmometer, and NanoDrop, ensuring they remain in peak operational condition. Learn new technologies quickly and apply effective scientific concepts and methods across multiple areas. Process and present data leveraging Microsoft Office apps, GraphPad and Spotfire for data organization and data visualization. Document experiments, data, technical reports, and findings electronically in an accessible manner with good documentation practices. Present findings, progress, and data proactively and regularly in group and department meetings. Possess a collaborative and willing-to-share mindset with excellent verbal and written communication skills, presentation skills, and attention to detail. Ability to follow Global Health, Safety & Environment Center (HSE) guidelines while performing tasks. Basic Qualifications: Bachelor's or Master's degree in Analytical Chemistry, Biochemistry, Chemistry, Food Science, or a related scientific field, with over 2 years of relevant post-graduate experience in industry. Additional Skills/Preferences: Strong analytical thinking skills with a demonstrated ability to articulate issues and extract and synthesize complex information into key focus areas. Extensive experience in operating and troubleshooting a range of mass spectrometers including Q-ToF, QQQ and Orbitrap Proficient with Thermo XCalibur, Agilent ChemStation and MassHunter software. Understanding tandem mass spectrometry and interpretation of MS/MS based characterization of including but not limited to peptide, peptide-oligonucleotide conjugates, and lipid conjugates. Extensive hands-on experience in downstream workflows for small molecules, biologics, and oligonucleotides. Experience with antibody-drug-conjugates (ADCs) or antibody-oligonucleotide-conjugates (AOCs) is a plus. Proven expertise in liquid chromatography including ion-pair reverse phase liquid chromatography as well as ion chromatography. Prior experience in native mass spectrometry and understanding of electrospray ionization as well as molecular behavior in the gas phase. Prior experience in proteomics, bioanalysis, and/or CMC is a significant advantage. Highly self-motivated and self-driven attitude with ability to own and drive projects into success. Strong organizational and communication skills and effective people skills. Capable of continuous learning, open-minded, highly organized, and detail oriented. Ability to balance multiple activities, prioritize and handle ambiguity. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly

We are seeking a highly motivated and innovative Scientist to support the discovery and development of gene therapies for rare genetic diseases. The candidate is expected to have proven practical technical capability and experience in, cell culture and cell based assays, protein purification and analytical assays. She/he should be scientifically motivated and capable of critically analyzing and interpreting data and reporting experimental results. Strong presentation and communication skills and the ability to work in a fast-paced and team-oriented environment will be vital. The position will support the development of a pipeline of gene therapy - associated product concepts while working in a cross- functional and collaborative environment Skills: • Experience with mammalian cell culturing techniques and cell based assays. • Experience with PCR, qPCR, Southern / Western blotting, Experience with FPLC / HPLC systems. • Ability to work in a team orientated, collaborative environment Strong communication and presentation skills • Prior experience with production and purification of AAV vectors is a plus Keywords: Education: BS/MS with a minimum of 8 years of related experience Qualifications BS/MS with a minimum of 8 years of related experience