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Senior staff scientist vs principal scientist

The differences between senior staff scientists and principal scientists can be seen in a few details. Each job has different responsibilities and duties. It typically takes 2-4 years to become both a senior staff scientist and a principal scientist. Additionally, a senior staff scientist has an average salary of $123,740, which is higher than the $119,982 average annual salary of a principal scientist.

The top three skills for a senior staff scientist include data analysis, FDA and next-generation sequencing. The most important skills for a principal scientist are oncology, data analysis, and drug discovery.

Senior staff scientist vs principal scientist overview

Senior Staff ScientistPrincipal Scientist
Yearly salary$123,740$119,982
Hourly rate$59.49$57.68
Growth rate17%17%
Number of jobs113,26580,899
Job satisfaction--
Most common degreeBachelor's Degree, 59%Bachelor's Degree, 51%
Average age4141
Years of experience44

What does a senior staff scientist do?

A Senior Staff Scientist is responsible for supervising projects and activities of a company. They manage the technical, budgetary, and scheduling aspects of scientific research projects.

What does a principal scientist do?

A Principal Scientist is focused on leading scientific teams and conducting research. They ensure that their teams have the resources to properly perform research tasks.

Senior staff scientist vs principal scientist salary

Senior staff scientists and principal scientists have different pay scales, as shown below.

Senior Staff ScientistPrincipal Scientist
Average salary$123,740$119,982
Salary rangeBetween $86,000 And $177,000Between $84,000 And $169,000
Highest paying CitySan Francisco, CASan Francisco, CA
Highest paying stateCaliforniaCalifornia
Best paying companyAirbnbPayPal
Best paying industryTechnologyFinance

Differences between senior staff scientist and principal scientist education

There are a few differences between a senior staff scientist and a principal scientist in terms of educational background:

Senior Staff ScientistPrincipal Scientist
Most common degreeBachelor's Degree, 59%Bachelor's Degree, 51%
Most common majorChemistryChemistry
Most common collegeDuke UniversityDuke University

Senior staff scientist vs principal scientist demographics

Here are the differences between senior staff scientists' and principal scientists' demographics:

Senior Staff ScientistPrincipal Scientist
Average age4141
Gender ratioMale, 74.7% Female, 25.3%Male, 76.8% Female, 23.2%
Race ratioBlack or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.5% Asian, 26.5% White, 53.6% American Indian and Alaska Native, 0.1%Black or African American, 6.3% Unknown, 4.1% Hispanic or Latino, 9.6% Asian, 26.4% White, 53.4% American Indian and Alaska Native, 0.1%
LGBT Percentage8%8%

Differences between senior staff scientist and principal scientist duties and responsibilities

Senior staff scientist example responsibilities.

  • Manage pediatric dose development project, technology transfer project and alternate API supplier qualification project on budget and on schedule
  • Conduct research and analyze data to identify potential biomarkers and provide input for selection of candidates for non-clinical studies development.
  • Establish methods for OTFT parameters extraction, physics-base device modeling, and circuit elements simulation.
  • Interpret metabolism data and review reports to support strategies forward thinking with a specialization in drug metabolism and metabolic enzymes.

Principal scientist example responsibilities.

  • Manage pediatric dose development project, technology transfer project and alternate API supplier qualification project on budget and on schedule
  • Provide development of and line support for assign immunoassay reagents, calibrators and controls.
  • Transfer controls to manufacturing for product launch and include all require studies, testing and documentation under GMP guidelines.
  • Maintain several lab documents for ISO certification.
  • Understand drug metabolism and pharmacokinetics and design stable molecules.
  • Image visualization and manipulation of background plates for animation and post-processing.
  • Show more

Senior staff scientist vs principal scientist skills

Common senior staff scientist skills
  • Data Analysis, 10%
  • FDA, 7%
  • Next-Generation Sequencing, 6%
  • Statistical Analysis, 5%
  • Regulatory Submissions, 5%
  • PK, 5%
Common principal scientist skills
  • Oncology, 7%
  • Data Analysis, 6%
  • Drug Discovery, 5%
  • GMP, 3%
  • Experimental Design, 3%
  • Clinical Trials, 3%

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