Synthes, Inc., together with its subsidiaries, develops, manufactures, and distributes instruments, implants, and biomaterials for the surgical fixation, correction, and regeneration of the human and animal skeleton and its soft tissues. It offers trauma implants and instruments for the treatment of fractures, deformities, and tumor diseases; and clinical solutions for shoulders and elbows, hands and wrists, hips and pelvis, knees, feet and ankles, pediatrics, and periprosthetics through screw and plate technologies. The company also provides spine implant products for the treatment of degenerative instabilities, fractures, tumors, and deformities by offering a range of solutions for the cervical, thoracic, and lumbar spine. In addition, it offers cranio-maxillofacial implants for the operative treatment of fractures of the mandible, mid-face, and skull; for the reconstruction of bones following tumor resections; and for the correction of deformities. Further, the company designs and manufactures surgical power tools, such as air, electric, and battery driven high and low power instrument systems, reamers, and saws for use in neurosurgery, neurotology, spinal procedures, otolaryngology, orthopaedic, traumatology, and cranio-facial surgery. Additionally, it provides biomaterials comprising bone substitutes and bioresorbable materials for the treatment in the areas of trauma, spine, and maxillofacial surgery. The company also offers plates, screws, biomaterials, and instruments for animal orthopedics. Synthes, Inc. markets its products primarily in the United States and internationally. The company is headquartered in West Chester, Pennsylvania. As of June 14, 2012, Synthes Inc. operates as a subsidiary of Johnson & Johnson.