Daiichi Sankyo Group is dedicated to the creation and supply of innovative pharmaceutical therapies to improve standards of care and address diversified, unmet medical needs of people globally by leveraging our world-class science and technology. With more than 100 years of scientific expertise and a presence in more than 20 countries, Daiichi Sankyo and its 15,000 employees around the world draw upon a rich legacy of innovation and a robust pipeline of promising new medicines to help people. Under the Group's 2025 Vision to become a "Global Pharma Innovator with Competitive Advantage in Oncology," Daiichi Sankyo is primarily focused on providing novel therapies in oncology, as well as other research areas centered around rare diseases and immune disorders.
Summary
The Director, Translational Pathology will work across the Translational Science matrix to develop and implement pathology-based translational approaches to assessing PD and patient selection biomarkers for Oncology and Specialty Medicine programs. They will further serve as the scientific expert supporting digital pathology investigations and as a point of contact for developing and managing external partnerships in support of translational science and CDx programs. They will provide the expertise to create and integrate pathology datasets with broader multi-omic analyses to support hypothesis-driven translational research efforts with direct impact across the Development continuum. They will work in a highly collaborative environment.
Responsibilities
- Design and build internal digital pathology capabilities and support data generation for translational pathology evaluations across the portfolio. Develop and manage partnerships, largely focused on digital pathology, to support design and implementation of translational pathology plans.
- Lead development of the translational pathology strategic direction and support data generation for assigned assets, with a focus on the design and implementation of translational pathology plans.
- Provide expertise to the Daiichi Sankyo Global Research Development organization to ensure access to state-of-the-art thinking on appropriate translational pathology strategies, evaluating their scientific basis and clinical applicability, the validation status and any technical or statistical issues related to proposed business plans.
- Communicate with portfolio leaders in Clinical Development, Discovery, QCP, CDx, RA, MA or other relevant functions to ensure effective integration of translational pathology strategy into broader Translational/Program strategies
Education Qualifications (from an accredited college or university)
- MD MD or MD PhD with Anatomic/Clinical Pathology board certification required required Experience Qualifications
- 4 or More Years 5 or more years of post-doctoral and relevant industry experience with expertise in pathology-driven translational research, biomedical leadership and human translational research in clinical trials required. required
- Experience with digital/computational pathology technologies and translational research. required
- Extensive experience in the discovery, characterization and utilization of innovative translational strategies across the continuum of preclinical and clinical stages preferred. Experience/knowledge in companion diagnostics device development preferred preferred
- Demonstrated ability to define clear translational strategies anchored in disease biology and drug mechanism of action, aligned with clinical development. required
- Deep knowledge in pathology-based and other biomarker technologies including immunohistochemistry (monoplex and multiplex), digital pathology, spatial analyses, NGS, immunoassay, proteomics including expertise in assay validation. required
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.