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Upstream biomanufacturing technician skills for your resume and career

Updated January 8, 2025
1 min read
Quoted experts
Daniel Lindstrom Ph.D.,
Kyle DiVito Ph.D.
Below we've compiled a list of the most critical upstream biomanufacturing technician skills. We ranked the top skills for upstream biomanufacturing technicians based on the percentage of resumes they appeared on. For example, 43.6% of upstream biomanufacturing technician resumes contained cell culture as a skill. Continue reading to find out what skills an upstream biomanufacturing technician needs to be successful in the workplace.

5 upstream biomanufacturing technician skills for your resume and career

1. Cell Culture

Here's how upstream biomanufacturing technicians use cell culture:
  • Monitored cell culture and harvest processes via the DCS (Distributed Control System).
  • Provided technical assistance to Principal Investigator and lab personnel -Molecular Biology, Cell Culture, non- survival animal surgery.

2. Harvest

Here's how upstream biomanufacturing technicians use harvest:
  • Assisted senior level manufacturing technicians within a cGMP facility in the fermentation and harvest of proprietary biopharmaceuticals for purification and packaging.
  • Participated and collaborated in a sugar beet growth operation from germination to harvest.

3. CIP

A Capital Improvement Plan (CIP) is a planning tool used to coordinate the timing and financing of capital improvements over a period of several years. It helps organizations make good budget decisions for large projects and purchases based on objectives and resources. The purpose of a CIP is to identify capital improvement projects, identify and forecast funding sources, prioritize improvements based on available funds, and estimate a timeline for completing the improvements.

Here's how upstream biomanufacturing technicians use cip:
  • Maintained inventory of raw ingredients, packaging materials and CIP chemicals to promote an efficient and well-organized pilot plant.
  • Used steam heating, air mixing and sanitation equipment daily including Cleaning IN Place (CIP).

4. Clean Rooms

As the name suggests, clean rooms are scientifically cleansed from microbes, dirt particles, and many other pollutants. It has a shallow level of external particles and is useful in the manufacturing and engineering of products. Since chemical reactions and scientific procedures can be affected by outside factors, they provide dirt and an interaction-free environment where scientific manufacturing can occur. Clean rooms are beneficial in various industries, including the aerospace, optics, and nanotechnology industries.

Here's how upstream biomanufacturing technicians use clean rooms:
  • Work on opened and closed systems in ISO, EU and cGMP clean rooms.
  • Qualified in microbiological monitoring of clean room environment.

5. Bioreactors

Here's how upstream biomanufacturing technicians use bioreactors:
  • Set up and operate wave bioreactors from 10L to 1000L.
  • Set up 250L and 1000L HyClone Single Use Bioreactors.
top-skills

What skills help Upstream Biomanufacturing Technicians find jobs?

Tell us what job you are looking for, we’ll show you what skills employers want.

What skills stand out on upstream biomanufacturing technician resumes?

Daniel Lindstrom Ph.D.

Associate Professor of Biology, University of Guam

I would expect that individuals that have developed skills that span disciplines will be the most desirable. For instance, someone who has mathematical/data analysis abilities or technical/laboratory skills/experience in addition to knowledge of basic biology will be far more employable. The pandemic has also forced us to rethink how to conduct business where physical distancing from coworkers is mandatory and those with computer application skills may have an advantage in this new abnormal world we have been forced to occupy. This may be a gift in disguise for already isolated places like Guam and may open an at a distance job market for some of our graduates. Historically, the bulk of the market for these types of jobs were near Mainland urban centers and large Universities and Medical Centers.

What hard/technical skills are most important for upstream biomanufacturing technicians?

Kyle DiVito Ph.D.

Associate Director of Biotechnology, Assistant Professor, Georgetown University School of Medicine

From my perspective, the technical skills that are frequently noticed are individuals with training in specific techniques such as gene editing (think CRISPR), vaccine development, tissue engineering, fermentation/bioprocessing skills, and broad knowledge of immunology. While these are a list of varied topics, the biotechnology sector itself is broad and varied, and therefore students or employees seeking to enter the discipline should consider taking courses in these areas or seeking professional advancement in one of the many opportunities that are available within this sector.

What soft skills should all upstream biomanufacturing technicians possess?

Kristen Johnson Ph.D.

Assistant Professor of Biotechnology, University of New Hampshire- Manchester

Communication, Team work, problem-solving.

What type of skills will young upstream biomanufacturing technicians need?

Dr. Roger S. Greenwell, Jr.Dr. Roger S. Greenwell, Jr. LinkedIn profile

Associate Professor, Biology Department Co-Coordinator, Undergraduate Biotechnology Program, Worcester State University

The skills that students should have as they graduate fall into two major categories: the technical skills and the interpersonal "professional" skills (often referred to as "soft" skills). The technical skills include scientific knowledge and laboratory practices, such as aseptic technique, pipetting, proper recording keeping, and so forth. An important technical skill is also following the established protocols and procedures without deviation. Those are skills many graduates gain through their coursework, independent research, and/or internship opportunities. Some advanced laboratory skills acquired (for example, hands-on experience with flow cytometry, electron microscopy, etc.) may be a requirement for certain roles, and that experience can make candidates stand out, but are not essential for every role as you are entering the field.

The second category, the interpersonal "professional" skills, are just as (or, arguably, more) important than the technical skills. Communication is at the forefront of these skills - being able to collaborate clearly and effectively with others, to problem solve individually and as part of a team, and to engage in purposeful and respectful interpersonal interactions. A person can have all of the technical skills needed but may struggle in the role if they cannot effectively communicate and interact with their colleagues.

The working environment, by its very nature, requires communication and collaboration for success. These communication skills can include things like writing an appropriate email, using active listening and having meaningful dialogues with colleagues, and receiving and processing constructive criticism. Problem solving and creativity are also skills that fall into this category - you have to have the initiative to seek the answers and address issues; at the same time, you also need to recognize when to ask for help and seek that assistance. Lastly, time management, being flexible to situations, and a willingness to work hard are the bedrock of the skills that will be expected for a professional in biotechnology (or any field, for that matter). A 2019 article in Scientific American by Karla Talanian from the Massachusetts Biotechnology Foundation (MassBioEd) highlights more of the "soft skills" that biotechnology companies and laboratories are looking for in their new hires and employees.

List of upstream biomanufacturing technician skills to add to your resume

The most important skills for an upstream biomanufacturing technician resume and required skills for an upstream biomanufacturing technician to have include:

  • Cell Culture
  • Harvest
  • CIP
  • Clean Rooms
  • Bioreactors

Updated January 8, 2025

Zippia Research Team
Zippia Team

Editorial Staff

The Zippia Research Team has spent countless hours reviewing resumes, job postings, and government data to determine what goes into getting a job in each phase of life. Professional writers and data scientists comprise the Zippia Research Team.

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