Researcher jobs at Vanderbilt University Medical Center - 21 jobs

Vanderbilt's University Medical Center, Division of Nephrology and Hypertension is seeking a Scientist to serve as a Research Instructor. Duties will include conducting bench research to model and develop novel biomedical technologies for renal replacement therapies. The Division of Nephrology and Hypertension has an active research program and there are excellent opportunities for candidates to develop their own programs or participate in ongoing studies. Applicants for the position must hold a minimum of a Ph.D., in Medicine, biochemistry, science, or a related field. Compensation will be dependent on the individual's qualifications.

The American Osteopathic Association (AOA) has two 100% remote 10-week summer research internship positions opening up. The internships are an opportunity to gain hands-on experience by assisting in research projects, engaging in literature reviews, data collection, data analysis, reporting, and potentially contributing to conference presentations and/or publications. The Intern Research Associate program at the AOA is for those currently enrolled in a Master's or PhD program in fields such as psychometrics, measurement, statistics, l/O psychology, or data science. This fully remote 10-week internship beginning June 2026 involves working closely with experienced psychometricians and assessment experts. Interns will gain hands-on experience with AOA data and research projects that support the organization's mission of advancing the distinctive philosophy and practice of osteopathic medicine. The Certifying Board Services (CBS) department serves 73 certification and certificate programs across 15 specialty certifying boards. Interns will work and collaborate with the psychometric and assessment teams of the CBS department to support the AOA's research agenda. The role provides an opportunity to support operational and research initiatives and offers practical experience in certification testing. Research topics may include exam design and development, administration and supportive validity studies for our certification and osteopathic continuing certification exams. Responsibilities Interns will work closely with the psychometric and assessment teams to develop a research plan for the internship. Over the 10 weeks, interns will attend weekly meetings with their supervisor to discuss progress and address questions, and with one or more research project teams to discuss ongoing work. Activities may include conducting and writing literature reviews, data gathering/cleaning, programming in R or Python, item and exam analyses with CTT and IRT, performing statistical analyses such as DIF or regression analysis, writing reports, and delivering presentations. At the conclusion of the internship, all files and equipment will be returned to the AOA. Current topics of interest to the AOA's Certifying Board Services: Application of AI in test assembly, content development, measurement and assessment fields Detecting compromised exam content Longitudinal assessment Detecting bias in exam content Qualifications Candidates must be actively pursuing a Master's or PhD degree in Educational Measurement, Statistics, I/O Psychology, or a related field and have completed a minimum of 75% of required coursework towards their Master's or 50% of required coursework towards their Ph.D. Recommendation of advisor, department chair, or other academic recommendation from current program of study Familiarity with Item Response Theory (IRT), Rasch modeling, Classical Test Theory, DIF analysis, and psychometric principles Intermediate programming skills in R and/or Python Strong research and analytical skills with attention to detail Interest in educational measurement, certification testing, LLMs, or data forensics Collaborative team player We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law. American Osteopathic Association is unable to sponsor work visas at this time.

NATIONAL LEADERS IN PEDIATRIC CARE Ranked among the top 10 pediatric hospitals in the nation, Children's Hospital Los Angeles (CHLA) provides the best care for kids in California. Here world-class experts in medicine, education and research work together to deliver family-centered care half a million times each year. From primary to complex critical care, more than 350 programs and services are offered, each one specially designed for children. The CHLA of the future is brighter than can be imagined. Investments in technology, research and innovation will create care that is personal, convenient and empowering. Our scientists will work with clinical experts to take laboratory discoveries and create treatments that are a perfect match for every patient. And together, CHLA team members will turn health care into health transformation. Join a hospital where the work you do will matter-to you, to your colleagues, and above all, to our patients and families. The work will be challenging, but always rewarding. It's Work That Matters. Overview This is 100% remote position. CHLA requires a primary residence in California prior to start date. Schedule: Per Diem, Days Purpose Statement/Position Summary: Under the supervision of the Research Associates/Research Managers, recruits project participants and administers structured and/or interview survey materials. May be responsible for data collection, data entry, and/or study documentation. May be responsible for coordinating small research and evaluation projects and staff. Duties are performed with supervision, feedback and guidance from principal investigators. May be responsible for tracking study participants throughout the project life. Minimum Qualifications/Work Experience: 2+ years of qualitative and/or quantitative interviewing experience required. * Experience using CASI interviewing tools preferred. * Experience working with children, youth, and families preferred. * Experience using Microsoft Word, Excel, and Access preferred. Education/Licensure/Certification: High school diploma or equivalent. College education in related discipline preferred. Pay Scale Information USD $44.30 - USD $44.30 CHLA values the contribution each Team Member brings to our organization. Final determination of a successful candidate's starting pay will vary based on a number of factors, including, but not limited to education and experience within the job or the industry. The pay scale listed for this position is generally for candidates that meet the specified qualifications and requirements listed on this specific job description. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. We provide a competitive compensation package that recognizes your experience, credentials, and education alongside a robust benefits program to meet your needs. CHLA looks forward to introducing you to our world-class organization where we create hope and build healthier futures. Children's Hospital Los Angeles (CHLA) is a leader in pediatric and adolescent health both here and across the globe. As a premier Magnet teaching hospital, you'll find an environment that's alive with learning, rooted in care and compassion, and home to thought leadership and unwavering support. CHLA is dedicated to creating hope and building healthier futures - for our patients, as well as for you and your career! CHLA has been affiliated with the Keck School of Medicine of the University of Southern California since 1932. At Children's Hospital Los Angeles, our work matters. And so do each and every one of our valued team members. CHLA is an Equal Employment Opportunity employer. We consider qualified applicants for all positions without regard to race, color, religion, creed, national origin, sex, gender identity, age, physical or mental disability, sexual orientation, marital status, veteran or military status, genetic information or any other legally protected basis under federal, state or local laws, regulations or ordinances. We will also consider for employment qualified applicants with criminal history, in a manner consistent with the requirements of state and local laws, including the LA City Fair Chance Ordinance and SF Fair Chance Ordinance. Qualified Applicants with disabilities are entitled to reasonable accommodation under the California Fair Employment and Housing Act and the Americans with Disabilities Act. Please contact CHLA Human Resources if you need assistance completing the application process. Our various experiences, perspectives and backgrounds allow us to better serve our patients and create a strong community at CHLA. PRA Kipke Lab

The research technician will work in Dr. Nancy Carrasco's laboratory in the Department of Molecular Physiology and Biophysics (MPB) at Vanderbilt University School of Medicine. The research technician will be responsible for experiments conducted in the laboratory, including: mouse husbandry, tissue culture, recombinant DNA studies, site-directed mutagenesis, microscopy (both light and electron), electrophysiology, transport assays, protein purification, western blots, and cryoelectron microscopy (CryoEM). This position will require scientific excellence, well-honed experimental skills, accuracy, the ability to conduct research according to a predetermined schedule, and the ability to report experimental outcomes to the supervisor (i.e., the lab head) effectively. In addition, this position requires skill at record-keeping and basic computer skills such as the ability to use Microsoft Word, Excel, and PowerPoint. The successful candidate must commit to remaining in the position for a minimum of two years. Therefore, the position is suitable for an entry-level scientist aiming to gain substantial experience in experimental research in preparation for applying to graduate programs. The laboratory has an excellent track record of producing scientists who have been admitted to PhD, medical, and MSTP programs at top universities. The Carrasco laboratory focuses on pushing forward our understanding of the action of thyroid hormones-from their biosynthesis in the thyroid gland to their pleiotropic effects on many different tissues. We express and purify wild-type sodium/iodide symporter (NIS) protein and mutant NIS proteins engineered by site-directed mutagenesis; ascertain the effects of the relevant mutations on NIS function; and determine the atomic structures of the mutant proteins using cryoelectron microscopy (cryo-EM). We also use NIS knockout mice to investigate the metabolic effects of varying degrees of hypothyroidism, and we are currently investigating novel approaches to employing not only wild-type NIS but also NIS mutant proteins in gene-transfer studies to image and treat several cancers. We value excellence, commitment, motivation, hard work, creativity, curiosity, and passion for science. Our overall experimental approach runs the gamut from engineering NIS cDNA constructs, expressing proteins in mammalian cells, membrane protein purification biochemistry, high-resolution structure determination using cryo-EM, image processing, light microscopy, and electrophysiology to investigating the molecular mechanisms of wild-type and mutant NIS proteins. The results of our research deepen our understanding of sodium-driven active transport and molecular endocrinology more generally, which may ultimately lead to translational approaches to treating thyroid disease and several cancers. Duties and Responsibilities Conducting research to their, and our, highest standards, as well as to the highest possible standards of responsible conduct of research. Following laboratory protocols, conducting experiments, and reporting results to the principal investigator (PI: Dr. Nancy Carrasco). The research assistant will report directly to the PI, and must be fully engaged in the research projects assigned to them. Reading relevant research literature and presenting research outcomes at our weekly lab meetings. Attending MPB seminars and other relevant seminars. Performing efficient data control and storage management by organizing notebooks, files, and file names in appropriate data storage folders associated with detailed data/file annotation. Making use of their strong interpersonal and communication skills and their ability to work collaboratively with a wide range of constituencies in a diverse community. Following laboratory safety guidelines and institutional safety protocols. Making a substantial contribution to relevant research projects, so that they can be included as a co-author on the papers published by the group. Assisting the PI with general laboratory maintenance and equipment repair, which will include communicating with vendors and manufacturers. Assisting the PI in training new lab personnel according to protocols approved by the PI. Education and Certifications: A bachelor's degree in a related field and laboratory experience is preferred. Experience and Skills: Excellent communication skills and good teamwork skills are required. General computer skills are required. Experience with the general laboratory techniques listed in the research description is strongly preferred. Experience with animal handling and/or husbandry is preferred.

The Research Scientist is part of the Wicked Problems Lab at the Institute of National Security at Vanderbilt University and is a key contributor responsible for providing research and developmental support for projects in artificial intelligence and cybersecurity. This position collaborates with research scientists, engineers, faculty, and external partners to assess threat landscapes, strengthen cyber resiliency, and accelerate the adoption of secure, advanced technologies across government, industry, and public-sector infrastructures. The Research Scientist will conduct experiments and execute on research proposals developed by the Principal Investigator across the domains of cybersecurity, artificial intelligence, and data science. This is a deeply technical position centered on data-driven analysis to defend against cyber threats as well as building and testing AI systems to support adaptive, mission-critical workflows. The Research Scientist will also be responsible for developing data-driven models relating to real-world events as well as engaging in hands-on deployment of cybersecurity and artificial intelligence-related hardware at partnered locations. This position reports to the Principal Investigator of the Wicked Problems Lab. About the Work Unit: The Wicked Problems Lab at the Vanderbilt University Institute of National Security focuses on high-impact challenges at the intersection of artificial intelligence, cybersecurity, and national security. The Lab brings together leading researchers, engineers, and operational experts to translate emerging technologies into pragmatic, real-world solutions. Work from the Wicked Problems Lab has been featured on the front page of The New York Times and has informed U.S. Congressional testimony. Key Functions and Expected Performance: Contributes research and development support to Institute portfolio of projects in artificial intelligence and cybersecurity Directly contributes to the technical mission(s) of the Institute of National Security and our sponsors, through activities including analysis, modeling, testing, design activities, and publication of research results Collaborates with internal and external stakeholders to reach desired project outcomes Provides leadership and direction to team members Maintains familiarity with emerging knowledge, technologies, techniques relevant to the Institute of National Security research discipline(s) and strategic goals Communicates regularly, effectively, and professionally with sponsors Functionally facilitates work for undergraduate and graduate students Other tasks as assigned Supervisory Relationships: This position may have supervisory responsibility over undergraduate and graduate students. This position reports administratively and functionally to Principal Investigator. Education and Certifications: A bachelor's degree in engineering or computer science is required. An advanced degree in engineering or computer science is preferred. Experience and Skills: 4+ years of experience in scripting languages (e.g., Python, MATLAB) is required. Technical and mathematical expertise in machine learning, artificial intelligence, computer vision techniques, and modern data science is required. Systems engineering experience working across disciplines is required. Strong written and oral communication skills - technical reports, published articles, large audience presentations - are required. Strong project management skills are required. Experience working with a variety of partners from different backgrounds and conveying complex technical concepts to each partner is required. Strong hands-on technical skills to help deliver an end-to-end functioning system that accomplishes research goals is required.

Job DescriptionThe Siciliano lab from the Department of Pharmacology at Vanderbilt University is seeking a self-motivated Research Assistant. Our lab research focuses on addiction and sensory neuroscience using cutting-edge technology to trace neural sensory tracts in combination with immunohistochemistry, optogenetics, in vivo fiber photometry, and behavioral pharmacology in rodents. Duties and Responsibilities Manage mouse colonies (experience with rodent colony management preferred) ● Experience with rodent behavior is preferred ● Experience with programmable microprocessors is a plus. ● Maintain laboratory inventories and ensure proper record-keeping ● Prepare reagents and other laboratory materials as needed ● Take initiative in delivering accurate results on time ● Collaborate and respond effectively to team needs ● Communicate clearly with lab members to ensure smooth workflow ● Trains new trainees and staff ● Self-motivation with a strong sense of personal responsibility and accountability is necessary Qualifications Bachelor's Degree Required

About the Work Unit: The Karbstein Lab in the Department of Biochemistry at Vanderbilt University is seeking an enthusiastic molecular biology/biochemistry research assistant to aid in the lab's studies of ribosome assembly, quality control and repair. In addition to providing a better understanding about the cellular mechanisms underlying ribosome integrity, this basic science work is highly relevant to cancer biology, the biology of aging. The lab relies heavily on biochemistry and molecular biology, as well as yeast genetics. For examples of the type of research that will be undertaken see: Blomqvist et al, 2023, PLoS Genetics; Yang et al, 2023, Mol Cell; and Parker et al, 2024, PLoS Biology; Yang&Karbstein, BioRxiv 2024. The lab is a mid-sized lab seeking a research associate who will spend their time performing research, with some time spent maintaining lab infrastructure. The new research associate will be directly mentored and instructed by Dr. Karbstein, the Principle Investigator, and plan, conduct, interpret and present research. The laboratory is a supportive, fast-paced environment for driven candidates who enjoy a collaborative atmosphere. It is expected that the new research associate will produce enough data for a first author publication within 1-2 years of joining the lab. The lab strives to be a diverse, inclusive, and equitable working environment; prioritizes personal growth and wellness; and is committed to work-life balance. Overall, this is an excellent opportunity for an experienced researcher who enjoys the independence of an academic lab. Key Functions and Expected Performances: Research and Development: Purifies ribosomes from various organisms for mass spectrometry analysis Experience in RNA biochemistry is an asset Uses protein gels, Western blotting and mass spectrometry to analyze ribosome assembly factors and ribosomal proteins Uses Northern blotting to analyze ribosome assembly in cells Uses agarose gels to analyze PCR screens and PCR reactions Generates yeast and worm strains and human cell lines Uses quantitative growth measurements to monitor genetic interactions Designs and clones proteins and RNAs for yeast, worm or human in vivo work and in vitro assays Analyzes RNAseq data Analyzes experiments independently and prepares them for presentation to the PI Supervisory Relationships: Might supervise interns, work-study students or undergraduate researchers. The position reports administratively and functionally to the PI Education and Certifications: A Bachelor's degree in cellular biology, molecular biology, biochemistry, or a related field from an accredited institution of higher education and a minimum of four years of experience is required. Experience and Skills: Ability to perform all basic calculations related to buffer composition (Molarity, dilution factor, etc.) is necessary. Experience with protein and/or RNA biochemistry is strongly preferred. Computational experience is preferred. Being comfortable in learning new assays is necessary.

We are looking for a full-time Research Assistant for the Vanderbilt Stress and Early Adversity (SEA) Lab, a fast-paced highly collaborative interdisciplinary research group exploring brain development, caregiving, and interventions to improve child and family functioning. Under the supervision of Dr. Humphreys, the Research Assistant will play an integral role in the day-to-day operations of multiple ongoing longitudinal studies. The Research Assistant will actively conduct data collection sessions with pregnant individuals, children, and families, including MRI and EEG acquisition, laboratory-based parent-child interaction assessments, home visits, and biospecimen collection. Beyond data collection, the assistant will contribute to participant recruitment and retention efforts, coordinate study visit scheduling across multiple protocols, assist with quality assurance through data auditing and management tasks, and support protocol development and refinement. This role provides opportunities to develop research coordination skills, including oversight of study timelines and enrollment targets, training and scheduling undergraduate and master's student research assistants, and general administrative support for study operations. The position balances independent responsibilities with collaborative teamwork, allowing the assistant to build competencies in participant engagement, technical research skills, data management, and scientific problem-solving. The Research Assistant will gain exposure to cutting-edge developmental neuroscience methods and clinical translational research. This position offers excellent research preparation and substantial responsibility and mentorship, making it ideal for individuals planning to pursue graduate programs in psychology, neuroscience, public health, or medical school. An ideal candidate would commit to a minimum of 2 years, allowing sufficient time to contribute meaningfully to study milestones and develop advanced research competencies. Supervisory Relationships: This position does have supervisory responsibility of undergraduate and master's level research assistants; this position reports administratively and functionally to Dr. Humphreys. Education and Certifications: Bachelor's degree in a relevant academic area Experience and Skills: Demonstrated experience conducting research data collection with human participants, with preferred experience in neuroimaging and EEG Experience working with pregnant individuals, infants, or young children in research or clinical settings preferred Strong participant-facing skills with ability to establish rapport, provide clear instructions, and create comfortable environments for sensitive or complex procedures Excellent interpersonal skills with warmth, professionalism, and cultural sensitivity when working with diverse populations

The Kuriyan lab studies the structural mechanisms of the protein switches that carry out cellular signal transduction. We use biochemical, biophysical, structural and cell biological analyses to elucidate molecular mechanisms of how proteins function, and also study how these mechanisms change with evolution. Aberrant signaling from these molecular switches underlies the onset of many human diseases, including several types of cancers. The Kuriyan lab is actively pursuing innovative approaches to modulate the functions of these targets and to advance the development of better therapeutics. Duties and Responsibilities: The individual is expected to support research activities that include, but are not limited to, molecular cloning, cell culture, protein biochemistry, and cellular analysis of protein function. The ideal candidate would have prior laboratory experience working in molecular biology, cell biology, biochemistry, or related fields. The ability to operate independently, as well as part of a team, is critical. Preferred experience and skills: Preparation of competent cells, LB medium, and agar plates Aseptic technique for handling bacteria and mammalian cell culturing Molecular cloning to prepare various constructs and variants of the proteins of interest with suitable vectors, for recombinant protein expression or cellular analysis Maintenance and subculturing of insect cell and mammalian cell lines Recombinant protein expression using E.coli, insect cells, or mammalian cells. Protein purification using centrifugation, affinity chromatography, ion-exchange, and size-exclusion chromatography Expression, purification, and in vitro reconstitution of integral membrane proteins Biochemical and biophysical assay development to measure protein activity, protein-protein, and protein-small molecule interactions General duties in laboratory research and development: Provide general support for everyday lab maintenance tasks Participate in laboratory meetings and planning sessions Collect, record, organize, and verify the accuracy of experimental data Qualifications A Bachelor's degree in molecular biology, biochemistry, cell biology, biological sciences, chemistry, or a related field from an accredited institution of higher education is necessary. 2 or more years' experience in biomedical research is necessary. Experience with organization, inventory, and record keeping is preferred Excellent organizational and communication skills (verbal and written) are preferred

The Research Assistant is part of the Visual Cognition Lab in the Psychology and Human Development Department at Vanderbilt University and is responsible for coordinating laboratory research. This will involve work on two related projects funded by grants from the National Science Foundation and the Templeton foundation. In the first project we are exploring technological supports for nursing simulation training. In this project there are two key themes. The first is to understand how on-line indicators of a first-person simulation learning experience such as gaze are structured by event perception, and can ultimately support reflection and self-regulation. The second is to develop technological supports for simulation education that improve learning by integrating event perception and self regulation. The second project explores attention, memory, reflection and, ultimately, deeper understandings derived from the experience of viewing morally-challenging films. Both projects focus on links between visual cognition and higher-level cognition, and they explore how people learn from highly meaningful events. This position involves administering cognitive testing, running participants in experiments, data management, coding, data analysis, training and supervising undergraduate assistants, some scholarly writing and publication, conference presentations, as well as various administrative duties and assisting with reports. The position reports directly to the Laboratory Director, Daniel Levin, but works in support of our full interdisciplinary team including: Vanderbilt Researchers Gautam Biswas (Computer Science), Meiyi Ma (Computer Science), Angela McNelis (Nursing), Alyssa Wise (Teaching and Learning), along with Allison Eden (Michigan State University), Carl Plantinga (Calvin University), Murray Smith (University of Kent). Supervisory Relationships: This position has some supervisory responsibility managing several undergraduate research assistants. This position reports administratively and functionally to the Laboratory Director. Education and Certifications: An bachelors degree in Psychology or related field from an accredited institution of higher education is necessary. Experience and Skills: Experience in conducting behavioral research studies involving adult participants is necessary. Experience in institutional review board processes is necessary. Experience with computer software including media, office, and statistical applications is helpful. Willingness to work some evenings and weekends is helpful. Experience scripting and/or programming is helpful. Experience supervising research assistants is helpful. Experience in conducting experiments involving eye movement data collection is helpful.

The Mchaourab laboratory is in search of a motivated research assistant who will play a role in the establishment of novel efforts aimed at characterizing neurotransmitter sodium symporters. The individual will be key personnel responsible for research conducted and support efforts of graduate students and postdoctoral fellows in the lab. This position requires knowledge of basic laboratory procedures, record keeping, and experience in molecular biology techniques and recombinant protein production. Determined individuals will have the opportunity to build their own project. About the Work Unit: Our overall approach integrates knowledge of protein structure with sophisticated spectroscopic methods and reaction kinetics to develop mechanistic models of functional dynamics. The lab capitalizes on state-of-the-art instrumentation at Vanderbilt, including cryogenic electron microscopy (cryo-EM) and electron paramagnetic resonance (EPR), to facilitate discoveries. Our goal is to uncover relationships between target molecular properties and disease-linked variants to aid rational drug design strategies. Duties and Responsibilities Manage, order and maintain inventory of lab reagents and equipment Apply molecular biology techniques to generate novel DNA constructs of target genes Express, purify and characterize recombinant proteins. Opportunity to perform independent research Qualifications The minimum requirement is a Master's degree in chemistry, biology or a related field is necessary.

The position is part of the Department of Pharmacology at Vanderbilt University. This role involves general lab maintenance, administrative duties, and overseeing compliance issues. The candidate will also set up and conduct experiments, report data, and continue research projects following established protocols under moderate supervision. We seek a dedicated individual with a long-term commitment to growing with our team. Every major advance in medicine starts with fundamental discoveries that teach us how living organisms work in both health and disease. These discoveries are made in biomedical sciences laboratories that study life at all levels from the individual molecules that encode heredity to the complex associations of cells that form tissues and organs. Vanderbilt Basic Sciences is a tightly integrated research and education division within the School of Medicine comprising four academic departments, eight interdisciplinary centers, twenty-seven service core facilities, and the Office of Biomedical Research, Education, and Training. Our team of over 1000 faculty, fellows, students, and staff are making new discoveries every day - discoveries that enrich our understanding of biological processes and provide the foundation for new insights into the causes, prevention, diagnosis, and treatment of human diseases. Duties and Responsibilities Provide administrative support to the Principal Investigator, including calendar management, meeting coordination, and correspondence. Prepare agendas and coordinate follow-up actions on lab and project meetings. Manage general paperwork of lab operations. Assist with preparation, coordination, and submission of grant applications. Under minimal supervision, plan, conduct and evaluate experiments and assays of varying complexity. Provide appropriate written/oral documentation of experiments. Analyze and summarize test results. Oversee purchasing of supplies, reagents, and equipment; negotiate with vendors when appropriate. Maintain inventory of consumables, clean glassware/lab space, prepare and aliquot stock solutions. Assist in the efficient operation of the lab. Aid in compound management duties. Qualifications A Bachelor's degree from an accredited institution of higher education in chemistry, biochemistry or similar field is necessary Strong interpersonal and communication skills and the ability to work collaboratively with a wide range of constituencies in a diverse community is necessary. Skill in organizing resources and establishing priorities is strongly preferred. Vanderbilt experience is preferred.

About the Work Unit: The Meydan Lab is interested in the mechanisms of protein synthesis, and the role of translation regulation and ribosomes in human health. We use various biochemistry techniques, sequencing of ribosome protected mRNA fragments, (a.k.a ribosome profiling (Ribo-seq), disome profiling (Disome-seq), and mitoribosome profiling), and RNA-seq in model systems of Saccharomyces cerevisiae (budding yeast), immortalized human cells, and neurons differentiated from induced pluripotent stem cells (iPSCs) to address our questions. Key Functions and Expected Performance: Assists in Research and Development: Collects data using appropriate lab experiments, procedures, and techniques Maintains knowledge of current literature on Meydan Lab's research focus Prepares buffers and reagents Generates and maintains plasmids, yeast strains and mammalian cell lines Analyzes and interprets data with assistance of other members of the laboratory Writes and updates laboratory protocols Reports on the status of research activities in oral and written formats Assembles and compiles research data for presentations and/or publications Maintenance Conducts general lab maintenance Assists in set up, operation, and maintenance of laboratory equipment including, but not limited to - biosafety cabinets, incubators, centrifuges, etc. Performs administrative duties Monitors inventory of supplies and assists with ordering Participates in one-on-one meetings and group lab meetings to discuss project progress Other tasks as directed by supervisor Supervisory Relationships: This position does not have supervisory responsibility. The position reports administratively and functionally to the PI. Education and Certifications: A Bachelor's degree in biochemistry, biological sciences, chemistry, or related field from an accredited institution of higher education is necessary. Experience and Skills: Knowledge and experience with mammalian cell culture, iPSC and neurons is preferred. Knowledge and experience with plasmid cloning is preferred. Knowledge and experience with next generation sequencing is preferred. Knowledge and experience of yeast growth and maintenance techniques is preferred. Experience with organization, inventory, and record keeping is preferred. Excellent organizational and communications skills (both verbal and written) are preferred.

The Kuriyan lab studies the structural mechanisms of the protein switches that carry out cellular signal transduction. We use biochemical, biophysical, structural and cell biological analyses to elucidate molecular mechanisms of how proteins function, and also study how these mechanisms change with evolution. Aberrant signaling from these molecular switches underlies the onset of many human diseases, including several types of cancers. The Kuriyan lab is actively pursuing innovative approaches to modulate the functions of these targets and to advance the development of better therapeutics. Duties and Responsibilities: The individual is expected to support research activities that include, but are not limited to, molecular cloning, cell culture, protein biochemistry, and cellular analysis of protein function. The ideal candidate would have prior laboratory experience working in molecular biology, cell biology, biochemistry, or related fields. The ability to operate independently, as well as part of a team, is critical. Preferred experience and skills: * Preparation of competent cells, LB medium, and agar plates * Aseptic technique for handling bacteria and mammalian cell culturing * Molecular cloning to prepare various constructs and variants of the proteins of interest with suitable vectors, for recombinant protein expression or cellular analysis * Maintenance and subculturing of insect cell and mammalian cell lines * Recombinant protein expression using E.coli, insect cells, or mammalian cells. * Protein purification using centrifugation, affinity chromatography, ion-exchange, and size-exclusion chromatography * Expression, purification, and in vitro reconstitution of integral membrane proteins * Biochemical and biophysical assay development to measure protein activity, protein-protein, and protein-small molecule interactions General duties in laboratory research and development: * Provide general support for everyday lab maintenance tasks * Participate in laboratory meetings and planning sessions * Collect, record, organize, and verify the accuracy of experimental data Qualifications * A Bachelor's degree in molecular biology, biochemistry, cell biology, biological sciences, chemistry, or a related field from an accredited institution of higher education is necessary. * 2 or more years' experience in biomedical research is necessary. * Experience with organization, inventory, and record keeping is preferred * Excellent organizational and communication skills (verbal and written) are preferred

About the Work Unit: The Karbstein Lab in the Department of Biochemistry at Vanderbilt University is seeking an enthusiastic molecular biology/biochemistry research assistant to aid in the lab's studies of ribosome assembly, quality control and repair. In addition to providing a better understanding about the cellular mechanisms underlying ribosome integrity, this basic science work is highly relevant to cancer biology, the biology of aging. The lab relies heavily on biochemistry and molecular biology, as well as yeast genetics. For examples of the type of research that will be undertaken see: Blomqvist et al, 2023, PLoS Genetics; Yang et al, 2023, Mol Cell; and Parker et al, 2024, PLoS Biology; Yang&Karbstein, BioRxiv 2024. The lab is a mid-sized lab seeking a research associate who will spend their time performing research, with some time spent maintaining lab infrastructure. The new research associate will be directly mentored and instructed by Dr. Karbstein, the Principle Investigator, and plan, conduct, interpret and present research. The laboratory is a supportive, fast-paced environment for driven candidates who enjoy a collaborative atmosphere. It is expected that the new research associate will produce enough data for a first author publication within 1-2 years of joining the lab. The lab strives to be a diverse, inclusive, and equitable working environment; prioritizes personal growth and wellness; and is committed to work-life balance. Overall, this is an excellent opportunity for an experienced researcher who enjoys the independence of an academic lab. Key Functions and Expected Performances: Research and Development: * Purifies ribosomes from various organisms for mass spectrometry analysis * Experience in RNA biochemistry is an asset * Uses protein gels, Western blotting and mass spectrometry to analyze ribosome assembly factors and ribosomal proteins * Uses Northern blotting to analyze ribosome assembly in cells * Uses agarose gels to analyze PCR screens and PCR reactions * Generates yeast and worm strains and human cell lines * Uses quantitative growth measurements to monitor genetic interactions * Designs and clones proteins and RNAs for yeast, worm or human in vivo work and in vitro assays * Analyzes RNAseq data * Analyzes experiments independently and prepares them for presentation to the PI Supervisory Relationships: * Might supervise interns, work-study students or undergraduate researchers. * The position reports administratively and functionally to the PI Education and Certifications: * A Bachelor's degree in cellular biology, molecular biology, biochemistry, or a related field from an accredited institution of higher education and a minimum of four years of experience is required. Experience and Skills: * Ability to perform all basic calculations related to buffer composition (Molarity, dilution factor, etc.) is necessary. * Experience with protein and/or RNA biochemistry is strongly preferred. * Computational experience is preferred. * Being comfortable in learning new assays is necessary.

The Siciliano lab from the Department of Pharmacology at Vanderbilt University is seeking a self-motivated Research Assistant I. Our lab research focuses on addiction and sensory neuroscience using cutting-edge technology to trace neural sensory tracts in combination with immunohistochemistry, optogenetics, in vivo fiber photometry, and behavioral pharmacology in rodents. The individual hired for this position will be directly supervised by PI Siciliano and expected to assist with experiments. Duties and Responsibilities Assist with mouse colonies management (experience with rodent colony management preferred) * Experience with rodent behavior is preferred * Experience with programmable microprocessors is a plus * Assist senior lab members in maintaining laboratory inventories and ensuring proper record-keeping * Prepare reagents and other laboratory materials as needed * Take initiative in delivering accurate results on time * Collaborate and respond effectively to team needs * Communicate clearly with lab members to ensure smooth workflow * Self-motivation with a strong sense of personal responsibility and accountability is necessary Qualifications * Bachelor's Degree required

About the Work Unit:The Lab in the Department of Biochemistry at Vanderbilt University is seeking a biochemistry research assistant to aid in the lab's study of biomolecular condensates. Biomolecular condensates are macroscopic structures that function to spatially organize biological functions and biochemical reactions within the cell. The lab is interested in elucidating mechanisms by which biomolecular condensates are utilized to execute proper animal embryogenesis and development. To understand the function, structure, and regulation of biomolecular condensates the lab utilizes multidisciplinary approaches including biochemistry, biophysical approach, genome editing, cell biology, single-molecule imaging, and super-resolution imaging. The work unit is made up of faculty, undergraduate students, and graduate students.Key Functions and Expected Performances: Assist in Research and Development Preparation of buffers and reagents Writing and updating laboratory protocols Production of DNA vectors for protein expression Overexpression and purification of proteins from bacterial and insect cells for biophysical characterization Use biophysical methods to characterize interactions of proteins Use microscopy approach to characterize cellular phenomena and biochemical reactions Writing and updating laboratory protocols Collecting and assembling research data for presentation and/or reports Participating in weekly meetings to discuss project progress Lab space maintenance Assists with orders and maintenance of inventory and supplies Other tasks as directed by the supervisor Supervisory Relationships: No supervisory responsibilities The position reports administratively and functionally to the PI. Education and Certifications: A Bachelor's degree in cellular biology, molecular biology, biochemistry, or a related field from an accredited institution of higher education is necessary. Experience and Skills: Ability to perform all basic calculations related to buffer composition (Molarity, dilution factor, etc.) is necessary. Ability to be organized, have excellent verbal and written communication skills, and show great attention to detail is necessary.

Job DescriptionThe Siciliano lab from the Department of Pharmacology at Vanderbilt University is seeking a self-motivated Research Assistant I. Our lab research focuses on addiction and sensory neuroscience using cutting-edge technology to trace neural sensory tracts in combination with immunohistochemistry, optogenetics, in vivo fiber photometry, and behavioral pharmacology in rodents. The individual hired for this position will be directly supervised by PI Siciliano and expected to assist with experiments. Duties and Responsibilities Assist with mouse colonies management (experience with rodent colony management preferred) • Experience with rodent behavior is preferred •Experience with programmable microprocessors is a plus • Assist senior lab members in maintaining laboratory inventories and ensuring proper record-keeping • Prepare reagents and other laboratory materials as needed • Take initiative in delivering accurate results on time • Collaborate and respond effectively to team needs • Communicate clearly with lab members to ensure smooth workflow •Self-motivation with a strong sense of personal responsibility and accountability is necessary Qualifications Bachelor's Degree required

At Vanderbilt University , our work - regardless of title or role - is in service to an important and noble mission in which every member of our community serves in advancing knowledge and transforming lives on a daily basis. Located in Nashville, Tennessee, on a 330+ acre campus and arboretum dating back to 1873, Vanderbilt is proud to have been named as one of "America's Best Large Employers" as well as a top employer in Tennessee and the Nashville metropolitan area by Forbes for several years running. We welcome those who are interested in learning and growing professionally with an employer that strives to create, foster and sustain opportunities as an employer of choice. We understand you have a choice when choosing where to work and pursue a career. We understand you are unique and have a story. We want to hear it. We encourage you to apply today so that you might become a part of our story. Vanderbilt University is an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran, or any other characteristic protected by law.