Director Of Strategy jobs at Vertex Pharmaceuticals

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia and Acute Pain. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Type 1 diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, among others. The Director, Market Access Strategy Lead - AMKD (inaxaplin) is accountable for leading and overseeing the development of Market Access (MA) strategies, tactical support programs and overall execution of access resources across all payer channels for the commercialization of inaxaplin. This role requires a significant degree of collaboration, influencing and driving strategic alignment across multiple functions (Account Management, Trade, Pricing & Contracting, US Public Affairs, HEOR, New Product Planning, Global Value & Access Strategy (GVAS), and Marketing). A few core elements include the development of the value proposition and PIE resources. Key Duties and Responsibilities: Provide critical leadership in developing brand and market access strategies by payer channel, to support patient access for inaxaplin via the creation and delivery of impactful market access resources Refinement and execution of the go to market access strategy to compete in a dynamic external landscape Lead initiatives to understand, analyze and demonstrate the clinical, economic, and societal value to payers, decision-makers, and influencers based on FDAMA114 guidelines (aka Pre-approval Information Exchanges) Develop, train, and implement the necessary promotional resources and reimbursement pull-through that support field account teams' efforts with key customers Chair the inaxaplin LRT process across the cross-functional business partners Collaborate with Internal stakeholders to plan and implement Market Research Customize strategies based on Commercial, Medicaid & Medicare demographics, legislation, & trends Identify and address key product barriers to payer access and performance by applying advanced payer analytics and market trends. Oversee agency and external vendors to deliver resources and strategic insights on time and within budget Accountable for LRM materials and training of Field team Developing KPIs and metrics to assess impact of key initiatives Act as trusted, subject matter expert on US payer landscape to internal colleagues and externally customers Knowledge and Skills: Expert knowledge of US healthcare system, including gov't & commercial payers, policy, and regulatory environment Previous contract strategy leadership experience in the pharmaceutical/biotech or healthcare industry Experience in developing and articulating a clear and pragmatic value proposition Proven track record of meeting or exceeding objectives & goals, both as an individual and as part of a team Excellent communication skills with experience presenting to customers and internal leadership Demonstrated ability to successfully lead cross-functional teams, influencing without direct authority, with the interpersonal skills to foster collaboration and succeed in a highly matrixed environment Ability to perform in a fast-paced environment, manage multiple priorities simultaneously, and work effectively across cross-functional teams Preference for candidate with prior, directly relevant product experience (i.e., kidney diseases, genetic diseases, companion diagnostics) and launch experience Education and Experience: Bachelor's degree Typically requires 8+ years of MA experience or the equivalent combination of education and experience Pay Range: $201,200 - $301,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Director, Pain, Global Value & Access Strategy role will serve as Market Access Lead for the chronic indications (DPN/LSR/PNP) across our Pain portfolio, with a specific focus on suzetrigine. Based on positive Phase 2 data, Vertex is advancing into pivotal development in diabetic peripheral neuropathy (DPN) and lumbosacral radiculopathy, or LSR, which is pain caused by impairment or injury to nerve roots in the area of the lumbar spine. The individual will be responsible for leading the development of Global Market Access strategies, as well as co-lead the Global Commercial Team across the Vertex Pain portfolio. The role reports to Sr. Director, Pain Portfolio lead. Key Duties and Responsibilities: Responsible for Global payer strategic planning to support value and access optimization for chronic indications (DPN/LSR/PNP) for suzetrigine as well as the broader Pain portfolio Lead development of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process Responsible for Global payer strategic planning to support value and access optimization; lead development of Global Payer Plan which integrates value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing Accountable for ensuring that payer and market access perspectives are reflected in all cross-functional strategies (e.g. commercial, product development, regulatory affairs) Ensure identification and prioritization of all evidence required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs Inform financial forecasts Partner with Health Economics & Outcomes Research (HEOR), Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement Co-lead the Pain Global Commercial Team, and work cross-functionally and cross-regionally to develop optimal commercial strategies The Global Commercial Team facilitates development of a commercial strategy in order to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy Team This role should ensure collaboration and drive alignment across Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial success Support P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly Collaborate closely with HEOR, International P&R, Corporate Affairs, US Market Access, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization Knowledge and Skills: Deep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plus Experience in leading cross-functional teams required Experience in specialty and/or rare disease access models preferred Demonstrated ability to think strategically and make sound pricing and market access recommendations Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen" Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex General experience in commercialization and drug development Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex Demonstrated relationship building at all levels of the organization and across geographies Recognized as a team player with excellent interpersonal skills who is flexible and reliable Displays sound ethics and a fit for Vertex's core values Education and Experience: Bachelor's degree in relevant discipline requiring quantitative analysis; advanced degree preferred Typically requires 8 years of experience or the equivalent combination of education and experience Pay Range: $201,200 - $301,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: As the Director, you will partner closely with leadership to translate strategic vision into actionable execution, enabling teams across various therapeutic areas-including Fertility, Neurology & Immunology, Oncology, and Endocrinology-to achieve their ambitions. Location: Boston/hybrid preferred, remote possible (with travel). Key Responsibilities: Cross-Functional Leadership and Execution: Serve as the primary liaison for therapeutic areas and operations, designing and executing projects that address key priorities and stakeholder requests. Go-To-Market Strategy and Planning: Drive the development of high-impact cross-functional go-to-market strategies for new and existing products within our portfolio. Field Operations: Manage quarterly targeting and alignment processes across therapeutic areas to ensure optimal field performance. Field Enablement: Collaborate closely with field leadership to ensure that teams are equipped with the right tools, resources, and information necessary for success. Performance Tracking and Reporting: Track and report on key performance indicators to monitor progress against strategic objectives and identify opportunities for improvement. Ad Hoc Market and Business Analysis: Conduct deep dive analyses of market trends, customer segmentation, and performance metrics. Utilize data-driven insights to inform strategic decisions, optimize resource allocation, and enhance overall business performance. Account Planning Strategy: Lead account planning and execution program, including developing resources for account planning teams, conducting regular reviews with senior leadership, and developing and executing against a roadmap for future capability expansion. Program and Project Management: Lead high-priority initiatives, ensuring structured execution, clear communication, and follow-through across stakeholders to achieve business objectives. Team Coaching: Mentor and guide team members, supporting their professional development through objective setting, performance appraisals, and coaching. Other responsibilities as assigned Who You Are Minimum Qualifications: 10+ years of experience in pharma/biotech or consulting in the healthcare industry (or Master's Degree plus 8yrs; or PhD plus 6yrs) Bachelor's degree in a related discipline Proven experience in a combination of Operations, Analytics & Insights, Marketing, Market Access, and / or Business Technology in the biopharma industry Advanced knowledge of CRM technology relevant to Field Teams Preferred Qualifications: Ability to leverage and analyze big data to tell a compelling story for leadership Strong business acumen with keen analytical sense and ability to utilize quantitative analysis and sound business judgment in interpretation of sales and market data to drive strategy Recent go-to-market experience in launching new products Executive Leadership capabilities Program and project management experience Experience assessing operational program performance to identify potential gaps and opportunities for program improvement A forward-thinking mentality with a strategic mindset, balancing long-term goals with short-term value creation Excellent leadership skills with ability to lead, inspire, and manage diverse team and work in a highly matrixed organization A proactive understanding of change management and the ability to lead through transformation to meet strategic imperatives Advanced problem-solving skills and the capacity to navigate abstract ideas and complex situations Strong strategic mindset with excellent communication and negotiation skills, enabling influence in critical matters Launch experience Account planning experience Experience in Fertility, Oncology, HIV, or Neurology/Immunology Ability to communicate openly and share information to foster trust while encouraging constructive debate, making informed decisions, and ensuring shared commitment to outcomes. Demonstrated willingness to take risks and stand up for what is right while prioritizing the needs and experiences of customers and patients in all decisions. Commitment to setting and reaching ambitious goals and setting high standards while acting in the best interest of the company and taking initiative to drive results. Uphold ethical standards and being honest in all interactions. Ability to streamlining processes to focus on what matters and creates impact and acting quickly to adapt to changes. Demonstrated ability to embrace new ideas, challenge the status quo, and seek innovative solutions while valuing diverse perspectives and treating others with respect and dignity. Pay Range for this position: $188,000 - 282,000 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here. What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Vertex is seeking an experienced commercial leader to implement field sales and non-personal promotion tactics in support of the North America Commercial (NAC) business. The Customer Strategy & Execution Lead (CSEL) will partner with North America commercial organization to implement the go-to-market (GTM) strategy and deliver customer solutions that meet the business needs. This role will lead a team of Associate Directors, Customer Strategy & Execution Leads and will work directly with the BU stakeholders, Field Operations Leads, Digital Operations Leads, Customer Data Management, and technical stakeholders to optimize HCP customer experience. This role reports to the Executive Director, North America Commercial Operations & Insight Analytics. Key Duties and Responsibilities: Lead a team of 3-4 Associate Directors, Customer Strategy & Execution Leads, each with specific business unit (BU) alignments In addition to leading the team, this role will have responsibility for the Cystic Fibrosis BU. In that capacity, partner with key business leaders to understand business strategy and translate to prioritized commercial operations needs to enable all customer-facing engagements Build and strengthen relationships with key leaders (heads of BU, Marketing, Field) - become a trusted partner and have an ongoing, significant impact towards meeting / exceeding strategic business goals Define and lead portfolio of projects of field enablement and marketing campaigns, ensuring quality and timeliness of delivery while remaining within allocated budget limits Co-develop HCP and patient customer journey maps across Field Operations and Digital Operations Conduct periodic after-action reviews to identify gaps and forward-looking opportunities in evolving technologies and potential business process improvements in pursuit of driving efficiencies and exceeding business goals Budget management / accountability- plan and manage financial resources for field enablement, field customer-facing activities, non-personal promotion Create and manage an integrated brand engagement playbook that enables cross-functional teams to have a singular source for key strategic and executional insights and plans (targeting, approved messages, engagement planning) Lead quarterly business planning sessions and document outcomes to ensure alignment across BU leaders on key upcoming priorities to prioritize work for key cross-functional enablement teams (e.g., DTE, DSS) Active participation in recurring BU Leadership Team Meetings to provide strategic recommendations to drive brand growth and proactively identify any risks or dependencies related to field and marketing engagement Qualifications 10-12 years' experience working in delivering customer-facing programs with at least 8-10 years of industry experience Experience in commercial launch readiness, supporting launch planning across multiple systems including CRM, Digital Customer Engagement, Reporting & Analytics, and Digital Marketing, etc. Able to translate broad business strategies and functional priorities into effective operational goals and objectives; able to actively participate in strategic planning for the function Results oriented leader with a proven track record of on-time project delivery for large, cross-functional, and complex projects with stakeholders Exceptional written and verbal communication skills and ability to present in a clear and concise manner to all audiences Exceptional analytical, quantitative, problem-solving, and prioritization skills, including the development of business cases/ value propositions Substantial program/ project management, demand management, resource management and system life cycle expertise Education and Experience Bachelor's degree required Advanced degree preferred Pay Range: $188,000 - $282,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Director, Global Pricing Analytics, Global Value & Access Strategy (GVAS) role will support the creation of a new Vertex Center of Excellence dedicated to Global Pricing Analytics. As Vertex continues to grow in size and complexity, this newly created team is needed to build industry leading capabilities in Global Pricing Analytics that will assess pricing strategies, measure performance, and deliver actionable insights across regions and across the portfolio. The role reports to Sr. Director, Global Pricing Analytics. Key Duties and Responsibilities: Support development of a Global Pricing Analytics capability to sustain value optimization for the Vertex portfolio Assess the current Global pricing data infrastructure and provide recommendations for future requirements Develop a set of Global Pricing Analytics deliverables to guide decision-making and performance assessments across Vertex disease areas and Regions Build a Global Pricing Analytics reporting infrastructure that integrates multiple data sources and automates insight delivery, including realized prices Serve as the Global Value & Access Strategy subject matter expert on Advanced Analytics, including appropriate integration of Artificial Intelligence Oversee operations for Global Price Governance including continual updating of guidance documents to audit standards, templates and Regional training Jointly own Global Price Policies with GVAS Disease Area leads, and manage the annual review process for Global price floors Develop disease specific performance analytics analyzing negotiation outcomes and achievement of business results relative to pre-deal analysis Provide strategic guidance for pricing capability development including lifecycle pricing, contracting strategies, launch sequencing and risk assessment in close cooperation with relevant stakeholders Partner with key stakeholders, including US and International Market Access, Global Value & Access Strategy, Global Commercial Strategy, Finance, and DTE to support the development of key Global Pricing Analytics deliverables Knowledge and Skills: Deep working knowledge of both US and ex-US healthcare systems required Working knowledge of US and/or ex-US pricing environment is required Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen" Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement principles to support Vertex Excellent working knowledge of the Market Access data sets including MMIT, IQVIA, Pricing / GTN (Model-N), and Real-World Data (DRG, Market Scan, etc.). Experience creating and/or supporting complex analytics and working closely with data scientists and engineers Strong proficiency in Tableau and/or Power BI, along with working knowledge of data lake platforms such as Snowflake is a plus. General experience in commercialization and drug development Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex Demonstrated relationship building at all levels of the organization and across geographies Recognized as a team player with excellent interpersonal skills who is flexible and reliable Displays sound ethics and a fit for Vertex's core values Education and Experience: Bachelor's degree in relevant discipline 8+ years of direct biotechnology / pharmaceutical industry experience Experience building an analytics platform, including data integration and visualization using tools such as Tableau and/or PowerBI Pay Range: $201,200 - $301,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Director, Speaker Bureau and Content Lead, US Kidney is responsible for setting up and leading the speaker bureau and developing all approved content to support our launches in IgA nephropathy (IgAN) and APOL1-mediated kidney disease (AMKD). Additionally, this person will map and prioritize all Key Thought Leaders (KTLs), Digital Opinion Leaders (DOLs), and Centers of Excellence (COEs) to support the KTL engagement strategy and identify opportunities for educational partnerships. We are seeking a candidate who has KTL and speaker bureau experience and a background in developing engaging content for peer-to-peer forums. This role reports to the Head of Market Development, US Kidney Business Unit. Key Duties and Responsibilities: Owns the development, management, and evolution of the speakers' bureau from end to end including speaker selection, training, and field activation Works cross-functionally to create and approve engaging educational content for peer-to-peer educational meetings Maps all KTLs, DOLs, and COEs and partners with marketing, medical, and sales operations to ensure an optimal engagement plan Collects, synthesizes, and disseminates insights from speaker programs Manages agency relationships to optimize spend and performance Models a culture of compliance focused on ethics and integrity in all we do Required Skills: Ability to drive large programs from ideation through execution Excellent cross-functional skills with strong customer orientation Content development including promotional review and approval Agency management to optimize budget and performance Innovative mindset when leading projects and solving problems Ability to generate insights and apply those insights to business problems/opportunities Ability to assess the impact of promotional investments and make strategic and tactical recommendations Strong planning, communication, and presentation skills Highly collaborative with the ability to manage multiple projects simultaneously Self-driven and accustomed to a fast-paced, launch environment Ability to travel up to 30% Required Education and Experience: Bachelor's degree Typically requires 10 years of experience in healthcare / biopharmaceuticals, or an equivalent combination of experience and education Experience in one or more of the following: product marketing, pharmaceutical sales, thought leader engagement, speaker bureau, market development, or ad agency Rare disease / specialty product launch experience Experience working in highly competitive markets Kidney experience preferred by not required Pay Range: $194,400 - $291,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex Pharmaceuticals is looking to hire an Associate Director, North America Commercial Field Team- Pain on a full-time basis. The AD will report to the Head of Pain Training to develop training materials/curriculum and enhance the skill and knowledge for our US field teams for our Pain portfolio. The ideal candidate must possess a unique blend of customer-facing field & pharmaceutical training experience, but most importantly scientific aptitude that will enable them to lead through science. The individual must be a strong collaborator to work cross-functionally within the US Commercial Team (Sales, Marketing, Managed Markets) but more importantly across the entire organization (Medical Affairs, HR, Legal, Regulatory and Compliance teams). Key Duties and Responsibilities: Leading training activities primarily for the strategic account teams (Health Systems) and front line managers (Coaching Effectiveness) Work cross functionally across our Pain program teams to develop, deliver and evaluate training programs, curricula and corresponding training materials and programs for field representatives and field leadership Designing relevant training modules and onboarding materials/curriculum in accordance with Medical, Marketing, Regulatory and Legal guidance Proactively identify training needs and develop effective strategies for deployment to field teams Organize, facilitate and continually improve field team(s) training and orientation, plan of action meetings and the roll-out of new materials Work with Commercial cross-functional teams to plan, design and deliver all training at National Meetings and POAs Develop and deliver initial and advanced training curriculum for new hires and current field team members to improve skills throughout their tenure to meet business goals Proactively conduct on-going communications with field management and other key stakeholders to identify training needs and develop specific training objectives and strategies to meet those needs Hold joint responsibility for creating and implementing field organizational development plans Represent Learning and Development in brand and business planning and product launches and/or label expansions Partner with HR team to ensure alignment with company learning and development philosophy Manage the identification and selection of vendors as well as manage subsequent relationships and projects relating to field training Stay abreast of learning, training and development best practices and current trends in pharmaceutical and life science industries - utilizing current advances within digital, live, and virtual platforms Document and maintain policies and procedures for areas of responsibility Partner with international colleagues to share best practices and create global efficiencies when required Effectively manage vendor relationships including deliverable dates & budget management Completion of ad hoc projects and analysis relating to group responsibilities as requested Education and Experience: Bachelor's Degree required. MBA or relevant Master's degree preferred 5+ years of experience in the pharmaceutical/biotech industry 2+ years Training and Development experience in field or training role Demonstrated proficiency in creating customized workshops for field teams based on instructional design/adult learning principles Proven communication skills with a well-developed ability to efficiently and productively communicate both verbally and in writing Ability to influence, collaborate and interact effectively with senior leadership and multiple key stakeholders across teams to align on objectives and provide consistent training direction Demonstrated excellence in project management and effectively managing multiple projects/priorities including budgeting and actual spend against budget is required Ensure that all training programs are consistent with, and supporting of, company legal, regulatory and compliance guidelines Skillful team player able to develop rapport and credibility with key stakeholders Ability to work independently and on a team; positive, team-focused approach is essential Experience with and ability to use Microsoft Office and associated tools (WORD, Excel, PowerPoint) Ability to travel domestically as needed Preferred Qualifications 3+ years of leadership experience (Field, HQ) In depth understanding of account management principles and engaging organized customer groups (IDNs) in complicated health ecosystems health systems Pain marketplace experience, clinical pain management experience, hospital sales, and JOURNAVX™ (suzetrigine) knowledge and/or selling experience Familiarity with traditional and modern training methods (mentoring, coaching, on-the-job or in classroom training, e-learning, workshops, simulations etc.) Commercial pharmaceutical training experience Experience as an account executive in complicated markets US Market Access training experience preferred Pay Range: $157,100 - $235,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex Pharmaceuticals is looking to hire an Associate Director, North America Commercial Field Team- Pain on a full-time basis. The AD will report to the Head of Pain Training to develop training materials/curriculum and enhance the skill and knowledge for our US field teams for our Pain portfolio. The ideal candidate must possess a unique blend of customer-facing field & pharmaceutical training experience, but most importantly scientific aptitude that will enable them to lead through science. The individual must be a strong collaborator to work cross-functionally within the US Commercial Team (Sales, Marketing, Managed Markets) but more importantly across the entire organization (Medical Affairs, HR, Legal, Regulatory and Compliance teams). Key Duties and Responsibilities: * Leading training activities primarily for the strategic account teams (Health Systems) and front line managers (Coaching Effectiveness) * Work cross functionally across our Pain program teams to develop, deliver and evaluate training programs, curricula and corresponding training materials and programs for field representatives and field leadership * Designing relevant training modules and onboarding materials/curriculum in accordance with Medical, Marketing, Regulatory and Legal guidance * Proactively identify training needs and develop effective strategies for deployment to field teams * Organize, facilitate and continually improve field team(s) training and orientation, plan of action meetings and the roll-out of new materials * Work with Commercial cross-functional teams to plan, design and deliver all training at National Meetings and POAs * Develop and deliver initial and advanced training curriculum for new hires and current field team members to improve skills throughout their tenure to meet business goals * Proactively conduct on-going communications with field management and other key stakeholders to identify training needs and develop specific training objectives and strategies to meet those needs * Hold joint responsibility for creating and implementing field organizational development plans * Represent Learning and Development in brand and business planning and product launches and/or label expansions * Partner with HR team to ensure alignment with company learning and development philosophy * Manage the identification and selection of vendors as well as manage subsequent relationships and projects relating to field training * Stay abreast of learning, training and development best practices and current trends in pharmaceutical and life science industries - utilizing current advances within digital, live, and virtual platforms * Document and maintain policies and procedures for areas of responsibility * Partner with international colleagues to share best practices and create global efficiencies when required * Effectively manage vendor relationships including deliverable dates & budget management * Completion of ad hoc projects and analysis relating to group responsibilities as requested Education and Experience: * Bachelor's Degree required. MBA or relevant Master's degree preferred * 5+ years of experience in the pharmaceutical/biotech industry * 2+ years Training and Development experience in field or training role * Demonstrated proficiency in creating customized workshops for field teams based on instructional design/adult learning principles * Proven communication skills with a well-developed ability to efficiently and productively communicate both verbally and in writing * Ability to influence, collaborate and interact effectively with senior leadership and multiple key stakeholders across teams to align on objectives and provide consistent training direction * Demonstrated excellence in project management and effectively managing multiple projects/priorities including budgeting and actual spend against budget is required * Ensure that all training programs are consistent with, and supporting of, company legal, regulatory and compliance guidelines * Skillful team player able to develop rapport and credibility with key stakeholders * Ability to work independently and on a team; positive, team-focused approach is essential * Experience with and ability to use Microsoft Office and associated tools (WORD, Excel, PowerPoint) * Ability to travel domestically as needed Preferred Qualifications * 3+ years of leadership experience (Field, HQ) * In depth understanding of account management principles and engaging organized customer groups (IDNs) in complicated health ecosystems health systems * Pain marketplace experience, clinical pain management experience, hospital sales, and JOURNAVX (suzetrigine) knowledge and/or selling experience * Familiarity with traditional and modern training methods (mentoring, coaching, on-the-job or in classroom training, e-learning, workshops, simulations etc.) * Commercial pharmaceutical training experience * Experience as an account executive in complicated markets * US Market Access training experience preferred Pay Range: $157,100 - $235,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex Pharmaceuticals is seeking a dynamic leader as the Director of Data and Analytics Capabilities to join our U.S. Market Access (USMA) organization leading transformative innovation within the Data & Analytics (D&A) Center of Excellence (COE). This is an individual contributor role that will over time lead a team of data analysts and scientists, offering a unique opportunity to shape and lead the future of AI-powered decision-making across Market Access functions while supporting one of the most innovative pipelines in the pharmaceutical industry. We are looking for a proven leader with a strong track record of designing and executing transformative AI/ML strategies-including emerging areas such as Generative AI and Agentic AI frameworks. This individual will bring deep domain expertise across at least two core pillars of U.S. Market Access, such as Pricing & Contracting, Trade & Distribution, Gross-to-Net Management, Chargebacks, Rebates & Discounts, and Market Access Strategy. As a senior leader within the D&A COE, the Director will work cross-functionally with senior executives across USMA, Commercial, and Enterprise functions to align data-driven insights with strategic business priorities. The ideal candidate will possess exceptional storytelling and executive communication skills, with a strong ability to drive organizational buy-in for data and analytics initiatives, influence stakeholders, and translate complex data into actionable, value-driven narratives. This role is not only about analytics-it's about leading change. The Director will elevate the impact of data science and AI by fostering innovation, championing data-centric thinking, and raising the analytical capabilities across key Market Access domains, from pipeline planning to in-market optimization. You'll join a purpose-driven team of Vertexians who are deeply committed to transforming the lives of patients, pushing the boundaries of science and technology, and delivering outcomes that matter. Key Duties and Responsibilities: This is an individual contributor position and reports directly to the Senior Director, US Market Access Data & Analytics COE. Vertex Pharmaceuticals is seeking a dynamic leader as the Director of Data and Analytics Capabilities to join our U.S. Market Access (USMA) organization leading transformative innovation within the Data & Analytics (D&A) Center of Excellence (COE). This is an individual contributor role that will over time lead a team of data analysts and scientists, offering a unique opportunity to shape and lead the future of AI-powered decision-making across Market Access functions while supporting one of the most innovative pipelines in the pharmaceutical industry. We are looking for a proven leader with a strong track record of designing and executing transformative AI/ML strategies-including emerging areas such as Generative AI and Agentic AI frameworks. This individual will bring deep domain expertise across at least two core pillars of U.S. Market Access, such as Pricing & Contracting, Trade & Distribution, Gross-to-Net Management, Chargebacks, Rebates & Discounts, and Market Access Strategy. As a senior leader within the D&A COE, the Director will work cross-functionally with senior executives across USMA, Commercial, and Enterprise functions to align data-driven insights with strategic business priorities. The ideal candidate will possess exceptional storytelling and executive communication skills, with a strong ability to drive organizational buy-in for data and analytics initiatives, influence stakeholders, and translate complex data into actionable, value-driven narratives. This role is not only about analytics-it's about leading change. The Director will elevate the impact of data science and AI by fostering innovation, championing data-centric thinking, and raising the analytical capabilities across key Market Access domains, from pipeline planning to in-market optimization. You'll join a purpose-driven team of Vertexians who are deeply committed to transforming the lives of patients, pushing the boundaries of science and technology, and delivering outcomes that matter. This is an individual contributor position and reports directly to the Senior Director, US Market Access Data & Analytics COE. Responsible for developing and executing a data & analytics capabilities that enables scalable insights across in line brands, pipeline assets aligning with US Market Access business priorities to drive business results and transform patient outcomes. Manage direct reports that have Data Enablement, Data Governance and Advanced Analytics responsibilities. Oversee the Data Enablement, to lead the establishment a common data foundation of analytics ready data products, ensuring seamless data and analytics capability integration across multiple data domains including payer accounts and field operations, pricing, chargebacks and reimbursements, trade and distribution and 3rd party data acquisition and vendor management. Oversee the Data Governance, to lead the implementation of a data governance framework, driving data discipline, integrity, security, and compliance to strengthen the baseline for D&A innovation Take charge of the Advanced Analytics capabilities, building a strong team over time, to enable real-time insights through AI-driven models, self-service analytics, and predictive intelligence to generate pipeline value narratives for market shaping, strengthen coverage and utilization via access expansion and barrier reduction, and drive launch success. Elevate analytics with Advanced ML, implementing multi-level analytical models to accurately attribute 340B vs. non-340B dispenses, stop 340B revenue leakage, using isolation forests for anomaly detection. Drive new KPIs and continuous performance monitoring in post-deal analytics, identifying opportunities for pull-through effectiveness and provide inputs to inform pre-deal feasibility assessment. Foster a data-driven culture by leading enterprise-wide data literacy and training initiatives, empowering Payer Field teams, Trade & Distribution, Pricing & Contracting teams to leverage AI/ML-powered insights. Lead change management efforts to embed Gen AI-enhanced data & analytics capabilities into strategic decision-making, ensuring agility and scalability including intelligent knowledge hub with conversational agent interfaces. Partner with Digital Technology & Engineering (DTE), GIACO (Global Insights Analytics & Commercial Operations), HEOR, DSS (Data Strategy & Solutions) to create a seamless AI-powered data ecosystem. Monitor emerging technologies, trends, and best practices, ensuring continuous innovation in ML, Generative AI, and analytics-driven decision-making. Partner with DTE (Digital Technology & Engineering), GIACO (Global Insights Analytics and Commercial Operations) members to describe the current state of the business and identify the factors influencing them (the “Why” behind the “What”). Serve as an advocate and develop strong partnerships in integrating market access insights across the Vertex enterprise. Minimum Qualifications: Master's degree in a quantitative discipline required (e.g., Engineering, Statistics, Economics, Finance) required. 10+ years of experience in the biotech/pharmaceuticals industries in Managed Markets or in biopharma consulting (analytics, management, or strategic) post-MBA/PhD, with meaningful biotech/pharmaceuticals and quantitative decision support experience. 7+ years of experience in developing insights that inform value, access, reimbursement, and contracting strategies. Proficiency in D&A with deep expertise in evolving U.S. Market Access strategies, payer account management, channel dynamics, payer/distribution channels (commercial, government, SP, GPOs, etc.). Demonstrated experience working with syndicated Market Access databases (IQVIA, MMIT etc.) and shipment data (852, 867, Integrichain, etc.). Strong analytical capabilities with expertise in data analysis tools (e.g., Excel, SQL, SAS, Alteryx, PowerBI), with a working knowledge of analytical tools/software such as R, Python and data warehouse platforms (Snowflake). Ability to network with internal and external stakeholders capable of forming strong, productive partnerships. Strategic thinker who can see operational trends, identify necessary activities, and summarize their impact to the bigger strategic picture. Strong written and verbal communication skills, strong presentation skills to C-suite management and external stakeholders. Flexible, adaptable, diplomatic, and able to effectively deal with ambiguity. Ability to partner and communicate with senior leadership to support financial forecasting and analytics, and/or commercial launch planning. Strong story telling skills with the ability to distill complex information synthesized into concise, impactful messages. Preferred Qualifications: PhD or MBA/ MPH in combination with a Master's in a quantitative discipline. Good understanding of state/federal policies, government programs impacting market access, and statutory government pricing methodologies. 8-10 years of pharmaceutical manufacturer market access experience and subject matter expertise with Health Plans, PBMs, Hospital Systems, Specialty Pharmacies and Healthcare Policy stakeholders. Diverse US product launch experience across different therapeutic areas strongly preferred. Pay Range: $201,200 - $301,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Sickle Cell Disease and Transfusion-Dependent Beta Thalassemia. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in Pain, Type 1 diabetes, IgA Nephropathy (IgAN), APOL-1 Mediated Kidney Disease, and Muscular Dystrophy, among others. The Director, Market Access Transformation & Strategic Marketing is accountable for leading the development of a strategic “above-brand” market access platform to help guide portfolio investments and support customer engagement as well as access across the Vertex portfolio. This role will focus on three core areas: Above brand initiatives that “connect the dots” within the Vertex portfolio along with the vertical integration of the large mega accounts (Payer & Trade); move from transactional relationships to professional alliances Customer and competitive insight mining to develop big innovative ideas which align and complement the transformative Vertex portfolio of products to bring the most value to patients (e.g., alternative contracting models, patient centric initiatives, health equity strategies and value frameworks) Elevate Market Access knowledge across the organization to ensure the latest Access trends are incorporated into product launch GTM strategies, pipeline, brand planning and long range planning initiatives Additionally, this will include conducting annual market landscape scans, and ensuring a streamlined, one Vertex voice related to customer engagements (preapproval information exchanges, value prop development and supporting deliverables) to ensure optimal impact and utility. This is a highly visible, cross functional role that will work closely with matrixed teams across the MA portfolio to ensure strategic integration, advancing long term MA goals. Key Duties and Responsibilities: Own and integrate Above Brand/Unbranded initiatives across the Vertex portfolio to advance customer interactions across the mega accounts and where applicable, broad, timely and sustainable access (including solution development, implementation, pull-through and measurement) alongside cross-functional leaders In tandem with HEOR, define strategic payer collaborations (i.e. health equity, quality, population health, etc.) with mega accounts (non-branded) across the various therapeutic categories Partner with the Access COE (data, analytics and insights) and CRM teams responsible for customer and data insight tracking across the broad and evolving access environment and Vertex portfolio Evaluate alternative contracting frameworks such as VBC/OBA/Warranties that support the clinical profile of the product and allow for easy measurement of a desire outcome Deliver impactful insights and analysis to shape GTM strategies Own and manage market access assessments/environmental scans to inform LRP assumptions including the development of action plans to manage risks and opportunities Provide an annual landscape assessment across all access channels to support brand planning and upcoming launches (Channels: Payers/Mega Accounts, IDNs, GPOs, SP/SDs, Pharmacy) as well as to establish prioritization of products across access channels Partner with external agencies and vendors as needed and ensure approvals and budget allocation as required. Establish a value framework and communication platform to deliver a portfolio of PVPs via HEOR integration leveraging IT capabilities; uniform look and feel and construct (PIE, PVP, etc..) to maximize customer engagements Knowledge and Skills: Expert knowledge of US healthcare system, including gov't & commercial payers, hospitals, IDNs, policy, and the regulatory environment as well as the flow of funds Previous strategic leadership experience in the pharmaceutical/biotech or healthcare industry; mega account experience Understanding of alternative Value Base Contracts and evaluate various models and drive initiative and strategies to support OBA, warranty like models. Proven track record of meeting or exceeding objectives & goals, both as an individual and as part of a team Excellent communication skills with experience presenting to customers and internal leadership Demonstrated ability to successfully navigate cross-functional teams, influencing without direct authority, with the interpersonal skills to foster collaboration and succeed in a highly matrixed environment Ability to perform in a fast-paced environment, manage multiple priorities simultaneously, and work effectively across cross-functional teams Education and Experience: Bachelor's degree in relevant field, Master's Degree preferred Deep market access experience (10 yrs) across all channels including experience in: payer marketing, contracting, Account Management (Payer) Typically requires 10-12 years of MA experience or the equivalent combination of education and experience Location: Remote, HQ or hybrid schedule (3 days a week in HQ) Pay Range: $201,200 - $301,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Associate Director, Consumer Digital Marketing will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with US immunoglobulin A Nephropathy (IgAN) patients as part of the US Povetacicept Marketing team within the US Kidney Business Unit. This role will focus on creating and implementing the consumer omnichannel communication journeys, including but not limited to display, CRM, social, and search integration while considering the evolving AI landscape. The Associate Director will also serve as the Consumer Digital lead for CRC, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities: Develop and execute consumer digital marketing strategies, including omnichannel communication journeys to reach and engage consumers effectively and precisely Lead the creation of Consumer digital assets, in alignment with strategic focus areas, including CRM, automated engagement tactics, banner ads, and website content Implement and optimize search, AI, and predictive analytics strategies to enhance digital marketing efforts and improve targeting and personalization Collaborate with cross-functional teams, including marketing, IT, analytics, insights, and compliance, to ensure seamless execution of digital marketing initiatives Define and oversee digital measurement frameworks, build performance dashboards, and translate analytics into actionable insights that inform targeting, content, and next-best-action strategies Stay updated on industry trends and best practices in digital marketing, consumer engagement, and regulatory compliance, infusing learnings as appropriate Serve as the CRC Digital lead, ensuring all digital marketing activities comply with regulatory and compliance standards Knowledge and Skills: Strong understanding of digital marketing strategies, including content creation, omnichannel ecosystem planning, and measurement design best practices Experience with CRM systems, real-time engagement (RTE) tools, banner ads, and website content management Proficiency in search and AI strategies for digital marketing Excellent project management skills, with the ability to manage multiple initiatives simultaneously Strong analytical skills, with the ability to interpret data from digital programs and provide actionable insights Excellent communication and collaboration skills, with the ability to work effectively with cross-functional teams Knowledge of regulatory and compliance standards in the pharmaceutical industry Education and Experience: Bachelor's degree in Marketing, Business, or a related field. Advanced degree preferred. Minimum of 7 years of experience in digital marketing, with a focus on patient engagement in the pharmaceutical or healthcare industry. Proven track record of developing and executing successful digital marketing strategies and campaigns. Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex is seeking a strategic and collaborative marketing professional to join our US Kidney Business Unit to support our aspirations of bringing Povetacicept to patients, a Phase 3 investigational therapy that has the potential to transform lives across multiple serious diseases. The Senior Patient Marketing Manager, US Kidney - will lead the strategic execution for the Patient marketing team within The US Kidney marketing team, which is preparing for potential commercialization of an investigational therapeutic being studied for the treatment of Immunoglobulin A nephropathy (IgAN) and other B cell-mediated diseases. This role will be pivotal in shaping and delivering impactful patient engagement strategies that support launch readiness, and drive awareness to Vertex's innovative treatment. The ideal candidate will bring deep experience in launch planning, patient-centric marketing, and cross-functional collaboration, with a passion for improving outcomes in the kidney disease space. This role reports to the Director, Patient Marketing for the US Kidney Business Unit and is based in Boston, MA. Key Duties and Responsibilities: Support the development and execution of patient marketing initiatives, including patient ambassador program and core marketing material rollout to support the launch of a new kidney disease therapy Translate patient insights into compelling, compliant messaging and resources that resonate with diverse patient populations Develop and update marketing materials that drive marketing strategy and business objectives Analyze material usage metrics to determine optimal patient education experience and ensure field sales utilization Manage agency partners effectively to deliver quality outputs, while ensuring adherence to budget and timeline Shape patient focused market research efforts and infuse learnings throughout key business processes Ensure consistency of messaging across channels and touchpoints, tailoring communications to patient needs and cultural considerations Drives assets through internal Communications Review Committee process Collaborate cross-functionally with the field, HCP Marketing, Patient Advocacy, and Market Research partners Knowledge and Skills: Ability to understand all elements of brand strategy and role in executing that strategy Broad understanding of regulatory rules and regulations with direct experience with communications review committee for review of tactics Exhibits ownership and broad accountability for projects and internal assignments; understand when it is appropriate to flag issues to management Ability to understand insights and the implications, and apply those insights to tactics, business problems, and opportunities Experience in pharmaceutical marketing, or closely related field(s) (e.g., pharmaceutical sales, ad agency, etc.) Proficient in launch planning, patient engagement strategy, and promotional initiatives. Education and Experience: Bachelor's degree required; advanced degree (MBA, MPH, PharmD, or similar) preferred Typically requires 6+ years marketing, consulting or agency experience in healthcare / biopharmaceuticals and demonstrated supervisory / management experience, or an equivalent combination of experience and education Additional preferred experiences: Specialty product launch experience Work within highly competitive markets Kidney experience Pay Range: $138,400 - $207,600 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Associate Director, HCP Marketing works within the HCP Marketing team for Vertex's U.S. Commercial Pain Business Unit and reports to the Senior Director, HCP Marketing. In Q1, 2025, Vertex launched JOURNAVX, an oral, non-opioid medication for the treatment of moderate-to-severe acute pain. To engage multiple HCP specialties involved in treatment of acute pain treatment in adults, promotion will expand to a new set of HCP customers, including office-based (surgeons, internists, oral surgeons among others) with new Customer engagement team (i.e. sales team) which is being hired and deployed. This role has responsibility for working within the HCP team to identify opportunities within this customer group for promotion, adapt and develop new materials appropriately and support the success of the Customer engagement team in driving customer interest and demand for JOURNAVX. Key Duties and Responsibilities: Work with Market Insights to assess the practice and educational differences and needs for this customer group as pertains to other existing (e.g. hospital-based surgical and anesthesia) specialties and translate them into overall promotional strategy Identify and develop or adapt materials for the team to use in promotion with these HCPs as well as develop other promotional initiatives that would be impactful. These include emerging digital media and technology assets Manage agency focus and internal processes to achieve work targets on time and within budget. Work in close partnership with other HCP marketing leaders (i.e. brand promotion lead for other customer team, media specialists, CRM lead, Congress and Speaker programs) to ensure overall HCP promotional mix and initiatives are maximized and synergies realized across the team Support launch including information and training needs of a newly formed Field sales team Maintain close working relationships with Field leaders to evolve and respond to needs Work with Market Insights and analytics partners to plan and measure effectiveness of promotion as well as gaps among target customers Other related duties as needed Knowledge and Skills: Ability to oversee generation of insights and apply those insights to business problems/opportunities Strong analytical mindset to lead others to solve complex problems Demonstrated ability to develop strategy, make strategic recommendations, and monitor performance Agency management and marketing material development, implementation and assessment (min 2 years) Direct experience with communications review committee (CRC) for review of tactics and compliance processes Experience with assessing impact of promotional investments Ability to work across large teams to both influence and support to get outcomes for team success Strong communication and presentation skills including comfort with Field discussions Agility in thought and action, ability to function in a fast-paced, brand-launch environment Education and Experience: Bachelor's degree in marketing, business, or scientific degree or equivalent; combination of scientific and business/marketing degrees preferred Minimum of 6 years of experience in pharmaceutical marketing or closely related fields (e.g., pharmaceutical sales, ad agency, etc.) Field experience (including training, promotional initiatives and planning, etc.) and HCP direct interfaces (Congresses, Advisory/consulting work, market research, etc.) Strong budget management and program management experience Ability to travel 25% of time Pay Range: $162,800 - $244,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Associate Director, Media/Social Marketing - HCP will lead the development and execution of comprehensive media and social marketing strategies to enhance the digital presence and engagement of the US Kidney business unit. This role will focus on driving influencer strategies, managing digital opinion leaders (DOLs), and leading HCP media planning and execution. The ideal candidate will have a strong background in media planning, media buying, analytics measurement, as well as channel selection and optimization. Key Duties and Responsibilities: Oversee media planning and media buying activities to ensure effective allocation of resources. Develop Marketing content for media platforms for HCPs. Develop and implement social media strategies, including influencer strategies and managing digital opinion leaders (DOLs). Define and oversee digital measurement frameworks, build performance inform targeting, content, and strategies. Select and optimize channels to maximize reach and engagement. Collaborate with technology partners to integrate digital technologies and enhance marketing strategies. Knowledge and Skills: Experience in HCP Marketing Proven experience in social media strategy development and execution Strong understanding of influencer strategies and HCP digital opinion leaders (DOLs) Excellent leadership and communication skills Proficiency in media planning and media buying Strong analytical skills with the ability to measure and optimize KPIs Experience in channel selection and optimization Ability to collaborate effectively with cross-functional teams and external partners Education and Experience: Bachelor's degree in Marketing, Communications, or a related field Minimum of 7 years of experience in media and social marketing, preferably in the healthcare industry Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Povetacicept is a pipeline in a molecule with a potential to transform treatment outcomes for patients. The Director, Global Marketing of Povetacicept is accountable for key indications understanding the market landscape and Vertex's position within the market, actively contributing to defining the strategy and performance goals of the portfolio and tracking performance against those goals. Key Duties and Responsibilities: Develops the indication strategy for povetacicept for key indications, and oversees creation of brand strategies and lifecycle activities including launch planning and prioritization Oversees development and implementation of strategic and tactical plans working across functions for a unified indication plan Provides input into forecasting assumptions, both short term and long term Generates and consolidates key insights across HCPs and patient stakeholders (through market research, ad boards, etc.) Leads the development of strong partnerships with cross-functional team to support business goals including R&D and regional teams Knowledge and Skills: Experience defining the strategy for a brand or portfolio of products with multiple indications/pipeline in a product Ability to oversee generation of insights, and apply those insights to business problems/opportunities Analytical mindset, with demonstrated ability to develop strategy, make strategic recommendations, monitor performance, understand ROI and allocate resources Exceptional working knowledge of market forecasts and relationship of business drivers to revenue Experience in pharmaceutical marketing. In-market and /or global marketing experience required. Neurology experience preferred. Education and Experience: Bachelor's degree in marketing, business, or scientific degree Typically requires 12 years of experience or the equivalent combination of education and experience Pay Range: $195,200 - $292,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

The Associate Director, Digital Marketing HCP will be responsible for developing and executing digital marketing strategies to enhance the engagement and communication with healthcare professionals (HCPs) within the US Kidney Business Unit. This role will focus on creating and implementing omnichannel communication journeys, non-personal promotion (NPP) execution, and leveraging search and AI strategies. The Associate Director will also serve as the Legal and Regulatory HCP Digital lead, ensuring alignment with regulatory and compliance standards. Key Duties and Responsibilities: Develop and execute HCP digital marketing strategies, including content creation and omnichannel communication journeys, to reach and engage HCPs effectively Lead the execution of non-personal promotion (NPP) initiatives, including CRM, automated engagement tactics, banner ads, and website content Implement and optimize search, AI, and predictive analytics strategies to enhance digital marketing efforts and improve targeting and personalization Collaborate with cross-functional teams, including marketing, IT, analytics, insights, and compliance, to ensure seamless execution of digital marketing initiatives Define and oversee digital measurement frameworks, build performance dashboards, and translate analytics into actionable insights that inform targeting, content, and next-best-action strategies Stay updated on industry trends and best practices in digital marketing, HCP engagement, and regulatory compliance Serve as the Legal and Regulatory Digital lead, ensuring all digital marketing activities comply with regulatory and compliance standards. Knowledge and Skills: Strong understanding of digital marketing strategies, including content creation, omnichannel communication, and non-personal promotion (NPP) execution Experience with CRM systems, real-time engagement (RTE) tools, banner ads, and website content management Proficiency in search and AI strategies for digital marketing Excellent project management skills, with the ability to manage multiple initiatives simultaneously Strong analytical skills, with the ability to interpret data from digital programs and provide actionable insights Excellent communication and collaboration skills, with the ability to work effectively with cross-functional teams Knowledge of regulatory and compliance standards in the pharmaceutical industry Education and Experience: Bachelor's degree in Marketing, Business, or a related field. Advanced degree preferred Minimum of 7 years of experience in digital marketing, with a focus on HCP engagement in the pharmaceutical or healthcare industry Proven track record of developing and executing successful digital marketing strategies and campaigns Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Biologics, Cell and Gene Therapy is a rapidly growing part of Vertex Pharmaceuticals where research, development, and clinical manufacturing are highly integrated together at our new R&D site in Boston Seaport. Vertex is seeking a highly skilled technical leader to join our Process Development / Engineering team to lead the development and manufacturing of biologics drug products for our growing pipeline. The Vertex Process Development team offers a dynamic, fast-paced, and highly collaborative environment with a tremendous impact on our programs and for our patients. Our team focuses on bringing together the best process design, scale-up and cutting-edge manufacturing technologies to enable the successful implementation of Biologics, Cell and Genetic therapeutics. The successful candidate will lead the development and manufacturing of biologics drug products. The responsibilities include formulation development, primary container development, fill-finish process development, technology transfer of manufacturing processes to CDMOs, and process validation to support our clinical pipeline toward commercialization. This is a highly cross-functional role that will work closely with drug substance development, analytical development, device development and supply chain management in CMC teams to drive technical and strategic decision-making. Key Duties and Responsibilities: Lead phase-appropriate strategies for drug product development, process transfer, scale-up and process characterization to support commercial readiness. Set-up and oversee external capabilities for developability assessment and formulation screening for high concentration biologics, ADCs and other biologics modalities. Define and develop robust fill-finish manufacturing processes for liquid and lyophilized drug products in vials, pre-filled syringes and other novel primary packaging. Oversee drug product technology transfer, process development and GMP manufacturing operations at CDMOs. Define and develop clinical dose preparation and administration strategies for drug products for multiple indications. Collaborate with clinical and supply chain teams to prepare clinical study documentation. Collaborate with the device development team to develop combination product presentations such as pre-filled syringes, autoinjectors and advance delivery technologies. Define and implement drug substance and drug product stability and shelf-life assessment approaches. Develop and manage project timelines, resource allocation, and budget for drug product programs. Manage deviations and OOT/OOS investigations at the CDMOs in collaboration with Quality, External Manufacturing and Regulatory team. Define and implement control strategies, validation protocols, and process characterization studies in accordance with Quality by Design (QbD) principles. Author and review regulatory submissions: IND/IMPD, briefing books and BLA. Serve as a subject matter expert in regulatory agency interactions, audits, and inspections. Identify and implement innovative technologies and best practices to improve process robustness, efficiency, and compliance. Potential in the future to build and manage a team of scientists and engineers to deliver high-quality, scalable, and compliant drug product processes from early development through commercialization. Expected travel: 10-20% (domestic and international) Required Education: PhD in Chemical Engineering, Biochemical Engineering, Pharmaceutical Sciences or related discipline with commensurate years of education and experience. Minimum of 11 years of experience in drug product development and manufacturing. MS with 14+ years of relevant experience may be considered. Required Experience and Skills: Expertise in formulation development of recombinant proteins including antibodies, ADCs, and fusion proteins. Expertise in developing stable, high concentration liquid formulation and dosage forms for biologics and applying cutting-edge technologies to develop stable drug products. Deep knowledge in developing aseptic fill-finish manufacturing process for biologics drug products in vials, pre-filled syringe and cartridge presentation. Experience successfully delivering development programs with CDMOs. Proven track record of advancing drug products from INDs into late phase development and commercialization. Experience with process characterization, process control strategy establishment and process performance qualification for commercialization using Quality by Design (QbD) principles. Extensive knowledge of cGMPs and regulatory guidelines for biologics and can serve as an internal thought-leader to drive decision making. Strong data analysis and scientific communication skills, including experience with regulatory documentation, with the ability to influence and drive decision making at multiple levels within a CMC organization. Demonstrated leadership with experience managing technical staff (internal or external) and cross-functional collaborations. #LI-LE1 Pay Range: $195,500 - $293,200 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Onsite Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

As a key Team Manager and leader in the Strategic Sourcing function, the Director, Strategic Sourcing Digital & User Orchestration Transformation leader is responsible for enabling the strategic sourcing organizational value delivery through relevant, effective, and optimized digital solutions enabling strategic and simplified solutions for users from business need through the source to pay end to end. This leader role is responsible for shaping and driving the digital strategy, technology enablement, and user experience within the global strategic sourcing and procurement function. This role will lead initiatives that simplify the procurement journey for business users, deploy advanced digital tools, and optimize end-to-end processes to deliver efficiency, transparency, and value creation across the enterprise. The ideal candidate is a forward-thinking leader with a deep understanding of procurement, digital technologies, change management, and user-centric design principles. Digital Transformation & Technology Enablement Define and execute the digital roadmap for procurement, aligning with enterprise technology and business strategies. Lead implementation and continuous improvement of Source-to-Pay (S2P) platforms, automation, and AI-driven solutions. Evaluate and integrate emerging technologies (AI, ML, RPA, analytics, GenAI, chatbots) to enhance decision-making and operational agility. User Experience & Orchestration Redesign procurement processes to prioritize simplicity, speed, and positive user experiences. Develop user journey maps to identify pain points and streamline the procurement interface for internal stakeholders and suppliers. Champion adoption by creating intuitive self-service tools, guided buying channels, and digital assistant capabilities. Process Optimization & Value Delivery Standardize and automate procurement workflows to reduce complexity and cycle times. Ensure digital investments deliver measurable business outcomes including cost savings, risk reduction, compliance, and improved supplier collaboration. Drive analytics and data-driven insights for proactive decision support. Develop and enforce policies and procedures to ensure compliance with global regulations and internal SOPs, regularly conducting reviews to assess compliance, gaps, and opportunities for improvement. Collaborate with cross-functional teams to ensure strategy to pay process integration, simple and visible user experience, streamline workflows, reduce cycle times, and enhance overall efficiency. Define key performance indicators (KPIs) for strategic sourcing and procurement processes and monitor performance against these metrics. Leadership & Change Management Partner with senior executives, business leaders, DTE, and suppliers to influence digital adoption and mindset shift. Align sourcing and procurement processes with overall business objectives and collaborate with key stakeholders to understand evolving needs; own, develop and embed tools and processes to enable consistency, simplification, and sustainability of strategic sourcing value to the business. Act as a change agent, embedding digital-first and user-centric culture across procurement. Foster strong partnerships and a culture of continuous learning and development within the strategic sourcing and procurement function to mature and sustain digital procurement journey and the value of the organization to the business. Success Measures Increased adoption and satisfaction with procurement tools and processes. Demonstrated cost, efficiency, and compliance improvements through digitalization. Reduction of procurement cycle times and user effort. High stakeholder engagement and positive business feedback on procurement's role as a strategic partner. Bachelor's degree in Business, Supply Chain, Technology, or related field (MBA or advanced degree preferred). Required Experience 10+ years of progressive experience in procurement, supply chain, or digital transformation roles, with at least 5 years in leadership. Required Knowledge/Skills Proven experience deploying large-scale procurement technology (Ariba, Coupa, Jaggaer, Ivalua, SAP, Oracle, etc.) and digital solutions. Strong knowledge of S2P processes, category management, and supplier engagement models. Track record of delivering measurable outcomes through process transformation, automation, and user experience redesign. Exceptional leadership, communication, and stakeholder management skills. Ability to operate strategically while driving operational execution. Able to establish and maintain strong business partner relationships at highest levels within the organization, partner on and shape strategies and develop multi-year plans to drive value for the business, gaining their respect and trust; Thoughtful and active listener; able to think quickly and effectively articulate points of view. Ability to work in collaborative, team environment; ability to cultivate and maintain effective business partner relationships through earned respect and trust Ability to manage multiple priorities while ensuring deliverables are fully met on-time, including more complex and involved projects. Once given direction, able to work autonomously with minimal support/direction from their Manager. Other Requirements Indicate required certifications, licenses or specialized trainings. Advanced degree (e.g. MBA) and/or supply chain professional designation preferred International assignments / experience a plus. Pay Range: $175,200 - $262,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Vertex is a global biotechnology company that invests in scientific innovation. The Digital, Technology and Engineering (DTE) Research, Pre-Clinical, Manufacturing & Supply (RPMS) Group's mission is to improve the lives of patients through data, and technology innovation - with AI at the core of our transformation strategy. Vertex is in a transformational period where we are accelerating our capabilities, technology and data to augment our mission and enable Vertex to grow in scale; ensuring we remain on the forefront of science, medicine and technology. The Senior Director, Supply Chain Data & Technology will define, lead and execute the vision for how Vertex will revolutionize our global Supply Chain through AI, data science and technology solutions. You will champion the adoption of AI-driven approaches to optimize supply chain operations, drive predictive analytics, enable intelligent automation across clinical and commercial supply based upon a foundation of robust transactional systems to plan, track and action supply chain activities. Working with multiple Vertex business units, the Senior Director is accountable for the end-to-end Supply Chain experience worldwide, across a broad range of internal and external teams, partner companies and operating models, powering both clinical and commercial supply. The role is a critical part of the Data Technology & Engineering leadership community. The Senior Director will bring their multi-disciplinary expertise to orchestrate innovation with leaders across Supply Chain, finance, legal, data science and technology, including core disciplines in infrastructure, data and software engineering, data science, architecture, portfolio and security, to ensure coordinated transformation through smart, scalable solutions. Reporting directly to the VP RPMS, the dynamic and experienced Senior Director, Supply Chain Data & Technology will play a key role on the RPMS Leadership Team to drive our digital transformation initiatives across Research, Pre-clinical, Manufacturing and Supply Chain. Key Duties and Responsibilities Vision and Strategy Develops, articulates, and executes a clear vision for delivering AI-powered technology solutions for Supply Chain worldwide, internally and externally, across multiple business units, in alignment with Vertex's strategic goals. Influences a broad internal and external landscape to cultivate a roadmap of opportunities to transform supply chain activities through cutting-edge AI technologies including generative and agentic AI, machine learning and data driven automation. Leads with agility to think strategically about planning, logistics, trade, business, product, and technical challenges simultaneously. Collaborates as a trusted partner to Supply Chain leadership to ensure technology strategies robustly accelerate portfolio and commercial goals and as key enablers of operational excellence. Operational Execution Specializes in driving transformative strategies that foster innovation, elevate organizational performance and drive growth. Leads in the identification of opportunities for innovation in delivery, evaluation of state-of-the-art AI (including generative AI and agentic AI), data product, data science, external and internal integrations, software, hardware and protocols, applicability and risks. Combines creativity, practicality and integrity to ensure technology solutions that are strategic, flexible, scalable, reusable and are achieved through the application of Vertex's architectural principles, standards and governance. Leads with rigor and discipline maximizing fiscal, resource and operational effectiveness. Manages an effective and efficient technology operation that enhances Supply Chain at Vertex, ensuring stakeholders can depend on technology as a robust enabler of drug research and production whilst maximizing ROI. Partners effectively with suppliers ensuring effective delivery aligned to Vertex's high expectations in compliance, quality and security. Leadership Leads and develops a high-performing, diverse team of professionals, fostering a culture of innovation, collaboration, and accountability. Creates a culture of inclusion, diversity, and equity where everyone can do their best work and feels valued. Aligns the Supply Chain technology team with enterprise priorities, ensuring data strategies drive business outcomes and regulatory compliance. Represent the Supply Chain technology organization in internal and external forums, advocating for its ability to achieve strategic goals and for innovation leadership. Required Education and Experience Bachelor's degree in science, engineering, computer science or a related field 10+ years of experience in life sciences technology or related fields. Relevant experience in creating and applying technologies to solve computationally intensive and data intensive problems in Supply Chain, inclusive of 5+ years in a leadership role. Required Knowledge and Skills Extensive knowledge of global Supply Chain environments to effectively understand user needs. Extensive technical knowledge and experience across broad range of complex Supply Chain technology. Extensive experience in applying AI and machine learning to solve complex, data intensive problems in global Supply Chain environments. Experience with varied compute environments including distributed, cloud and high performance computing. Experience of successfully developing and implementing technology strategy; preferably within a complex pharmaceutical Supply Chain organization. Expertise in successful development and delivery of multiple complex technology development initiatives. Strong leadership and team-building skills, with demonstrated success in managing diverse teams and fostering high engagement. Excellent communication skills including the ability to produce strategic documents, present ideas and solutions to technical and non-technical audiences and all levels of the organization. A strong commitment to compliance and integrity in systems, processes, and actions, with a deep understanding of the biotech regulatory environment. Exceptional problem-solving and strategic thinking abilities, with a focus on driving innovation and operational excellence. Other Requirements Experience with enabling advanced technologies, such as AI and machine learning, through data engineering strategies is highly desirable. Advanced certifications in product, agile, software engineering, cloud technologies, or leadership. #LI-hybrid Pay Range: $236,000 - $354,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com