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In 1955, Japan’s first radioisotope (RI) laboratory was established by Daiichi-Pure Chemicals to research and produce 14C labeled compounds..
But the lab soon expanded its niche role to also conduct the studies themselves, and in 1971 became the first in Japan to contract ADME studies in vivo.
The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) were cloned and/or established as xenobiotic receptors in 1998.
Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.[Pharmacogenomics J. 2002] Wei P, Zhang J, Dowhan DH, Han Y, Moore DD. Pharmacogenomics J. 2002; 2(2):117-26.
In 2016, the facility officially adopted the name Drug Development Solutions Center.
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| Company name | Founded date | Revenue | Employee size | Job openings |
|---|---|---|---|---|
| Pharm-Olam | 1994 | $55.1M | 400 | - |
| Catalent Pharma Solutions | 2007 | $4.4B | 14,000 | 337 |
| Inotek Pharmaceuticals | 1996 | $1.0M | 91 | - |
| Frontage Laboratories | 2001 | $560,000 | 50 | 161 |
| Tergus Pharma | 1994 | $11.6M | 116 | 11 |
| SCYNEXIS | 1999 | $3.7M | 24 | - |
| Interpharm Holdings Inc. | - | - | 670 | - |
| AMRI | 1991 | $276.6M | 3,085 | - |
| Collegium Pharmaceutical | 2002 | $310.0M | 266 | 10 |
| Neotropix | 2003 | $580,000 | 7 | - |
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Xenobiotic Laboratories, Inc., A Wholly Owned Subsidiary Of Wuxi... may also be known as or be related to XENOBIOTIC LABORATORIES INC, Xenobiotic Laboratories, Inc. and Xenobiotic Laboratories, Inc., A Wholly Owned Subsidiary Of Wuxi...