Xeris Pharmaceuticals jobs - 36 jobs

The Manager, Clinical Supply and Logistics will be the liaison between the Clinical Research Operations team and the Technical Operations team to facilitate cross functional collaboration for proactive problem solving and alignment of end-to-end clinical supply chain management to support clinical trial execution. This position will be responsible for supporting the strategic planning and execution of new clinical trial supply chains on time and within budget and is tasked with supporting an integrated operating model with close collaboration with cross functional stakeholders. **Responsibilities** - Oversees clinical supply labeling, packaging, release, distribution, return and destruction at contract manufacturing organizations. - Manages inventory globally at depots and sites including order management and proof of delivery confirmation, return or destruction and distribution logistics. - Acts as a key interface between the Technical Operations and Clinical Research Operations teams to operationalize supply strategy to maximize supply efficiency, minimize waste while identifying risk and develop risk mitigation plans. - Interprets protocol or study overview to calculate total demand and translation of total demand into a demand forecast over time. - Manages clinical supply activities for clinical trials including clinical supply needs identification, determination of appropriate presentation to clinical site and participants and IP expiry date management. - Collaborates with project team members including Technical Operations, Regulatory and Quality to design and implement drug labelling, packaging and supply strategies that not only meet the requirements of the study design, the clinical study sites, project timeline and the relevant regulatory authorities, but also maximizes efficiency of supply. - Leads the logistics of the forecasting, planning, and distribution of ancillary supplies for all clinical trials in conjunction with senior team members. - Coordinates supply strategies with internal Supply Chain/Technical Operations team and external packaging suppliers in conjunction with senior team members. - Manages external clinical vendors including IRT vendors, as assigned, in conjunction with senior team members. - Proactively identifies, prevents, and mitigates cross functional program risks related to clinical supply logistics. - Work with the cross functional project team to ensure consistent communication of clinical trial material supply chain status. - Collaborates with cross-functional study team members to ensure compliance of department/study activities with ICH guidelines, GxP, FDA and other applicable country regulations. - Other tasks as requested by managers. **Qualifications** - Bachelor's degree (B.A./B.S.) or equivalent, preferably in life sciences or related discipline. - 5+ years of related experience supporting clinical trial teams. - Experience managing clinical trial vendors. - A high level of proficiency in Microsoft Office (Word, Excel, PowerPoint, Outlook) is also required -Competencies: Teamwork & Collaboration, Attention to Detail, Analytical skills, Organizational skills, Written and Verbal Communications, Adaptability, Time Management skills -Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. This is a hybrid position based in Xeris' Chicago office. A minimum of three days per week in the office is required. On-site requirements may change at management's discretion. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $95,000-180,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process._ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Manager, Clinical Supply & Logistics_ **ID** _2025-2272_ **Category** _Clinical Development_ **Type** _Full-Time_

The Associate Director, Biostatistics and Statistical Programming will drive biostatistical activities, performed primarily by vendors, in support of project timelines and budgets related to drug product development at Xeris. The individual will contribute to study design, protocol development, case report form development, clinical study reports, and exhibits for other reports and presentations. **Responsibilities** + Conducts basic statistical analysis of study datawith minimal supervision according to a statistical analysis planto generate results and insights used to support study findings. + Applies moderately advanced statistical methods, which may include simulation models and other statistical programming as needed, with guidance. + Generates sample size and power calculations and randomizations. + Oversees the review of statistical documents and operational activities outsourced to CROs ensuring adherence to cost, timeline, and data quality requirements to ensure that the analysis plans use the most appropriate statistical methods and that the data displays such as tables/figures/listings are accurate and complete. + Programs or independently validates key study results to support interpretation of data. + Provides statistical programming support to other clinical studies or regulatory submissions where another biostatistician is assigned as the sponsor lead. + Works closely with Data Management by providing input to data management-related documents and assisting with data review and cleaning activities, as needed. + Ensures compliance of data packages to regulatory requirements and CDISC and industry standards. + Assists in the development of abstracts, manuscripts, presentations for scientific congresses. + Closely collaborates and participates in knowledge sharing with other team members including non-statisticiansto assist with interpretation and understanding of results. **Qualifications** + MS/MPH degree in biostatistics, statistics, or epidemiology + A minimum of six years of clinical trial experience as a statistician and/or statistical programmer in the pharmaceutical, biotech, or CRO industry + Experience in Phases I-III of the clinical drug development process + Knowledge and basic understanding of statistical concepts and techniques commonly applied to the analysis of data from clinical trials and the ability to tackle from basic to moderately complex statistical or data issues + Basic understanding of real-world data and observational studies. + SAS programming experience required, R experience is a plus + Working knowledge of CDISC standards + Prior use and implementation of sample size and power calculation software (e.g., nQuery and PASS) preferred + Working knowledge of EDC systems + Competencies: Attention to Detail, Organizational skills, Adaptability, Multi-Tasking, Strong Written & Verbal Communication skills, Teamwork & Collaboration, Critical Thinking, Problem Solving, Presentation Skills + Working Conditions: This is a hybrid position based in Xeris' Chicago office. A minimum of three days per week on-site is required. On-site requirement may change at management's discretion.Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $140,000 to $240,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process_ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Associate Director, Biostatistics and Statistical Programming_ **ID** _2025-2295_ **Category** _Clinical Development_ **Type** _Full-Time_

Reporting directly to the Vice President of Clinical Development, the Medical Writer will be responsible for leading and executing all medical writing activities supporting Xeris' clinical programs. The individual will have a strong scientific background, exceptional writing skills, and a proven ability to translate complex clinical and scientific data into clear, accurate, and regulatory-compliant documents tailored to diverse audiences. **Responsibilities** + Develop and authora broad range of clinical and regulatory documents, including but not limited to: clinical study protocols, investigator brochures (IBs), clinical study reports (CSRs), and sections of regulatory submissions (e.g., IND, NDA, etc.). + Ensure accuracy, clarity, consistency, and compliancewith internal standards, applicable regulatory guidelines (e.g., ICH, FDA, EMA), and company SOPs. + Collaborate cross-functionallywith colleagues in Clinical, Regulatory Affairs, Medical Affairs, and other internal stakeholders to gather relevant data and ensure consistency of messaging across documents. + Translate highly technical and statistical informationinto clear, concise content suitable for a wide variety of audiences including regulators, healthcare professionals, and non-scientific business leaders, as required. + Contribute to the development of communication materials, including slide decks, manuscripts, abstracts, and presentations, to support internal and external scientific communications. + Maintain document quality controlthrough proofreading, editing, and adherence to templates, style guides, and version control procedures. + Manage timelines and priorities for multiple projects simultaneously, ensuring timely and accurate delivery of high-quality documents. + Provides detailed medical editing review of draft and final documents prepared by other writers before internal or external distribution. This includes both copy editing and content review. + Ensures document content and style adheres to FDA/EMA or other appropriate regulatory guidelines and complies with departmental SOPs and style guidelines. + Performs literature searches and reviews as necessary to obtain background information and provide literature references. + Provide input on processes, templates, and other business needs within the medical writing function. + Coordinate and/or manage review cycles to triage, incorporate, and resolve team comments, and lead discussion on document revision and finalization for both internally written and outsourced documents. + Serve as a point person for medical writing guidance and document-related problem resolution. **Qualifications** + Bachelor's degree in Life Sciences or a related field is required; advanced degree (PhD, PharmD, or MS) strongly preferred. + Minimum of 5 years of medical writing experience in the pharmaceutical, biotechnology, or clinical research industry, with a focus on late-stage clinical development (Phase 3). + Demonstrated experience in writing regulatory submission documents in compliance with regulatory agency guidelines. + Proficiency in Microsoft Office Suite and familiarity with document management systems and version control tools. + Competencies: Attention to Detail, Organizational skills, Adaptability, Multi-Tasking, Strong Written & Verbal Communication skills, Independent Judgement, Cross-Team Collaboration, Critical Thinking, Problem Solving + Working Conditions:Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. _This is a hybrid position located in Xeris' Chicago office and requires three days per week on-site. On-site requirement may change at management's discretion._ _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $75,000 to $150,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process._ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Medical Writer_ **ID** _2025-2296_ **Category** _Clinical Development_ **Type** _Full-Time_

The IT Service Desk Lead is responsible for overseeing daily IT support operations, ensuring efficient service delivery, and driving continuous improvement across the helpdesk function in a Microsoft centric environment. This role serves as a key liaison between end-users and technical teams, ensuring secure, scalable, and premium support for both office and field-based employees. **Responsibilities** + Lead daily IT support operations across office and field teams, ensuring timely resolution of issues and minimal business disruption, utilizing ITIL best practices. Serve as the primary escalation point for complex technical problems and high-priority service requests. + Own and evolve ITSM processes (incident, service request, change and problem), document repeatable procedures, and lead support-related projects. + Incident Management - Lead incident response efforts by prioritizing and resolving IT issues swiftly, coordinating with support teams to minimize disruption, meet SLAs, and drive continuous improvement through analysis and reporting. + Service Request Management - Manage and optimize the service request lifecycle, ensuring timely fulfillment, process efficiency, and alignment with ITIL best practices of user requests in alignment to enhance user experience and operational performance. + Change Management - Coordinate and oversee change management activities, ensuring proper assessment, approval, and communication of changes to minimize risk and disruption to IT services. + Problem Management - Drive problem management processes by identifying recurring issues, performing root cause analysis, and implementing long-term solutions to improve service stability and reduce incident volume. Lead and report to management on a regular cadence. + Project Management - Lead support center projects, integrating new technologies and driving successful implementation. + Asset Management - Manage the lifecycle of user-facing technology, maintain accurate asset inventory, and enforce IT security protocols. + Take ownership of support issues, engaging other internal / external expertise as required. + Ability to communicate complex technical information to all stakeholders, including those who do not have a technical background. + Continuously educate employees and equip them with essential IT tools and best practices. **Qualifications** + Associate or bachelor's degree in information technology or equivalent work experience preferred + 5+ years of progressive experience in IT support/helpdesk roles + Proven supervisory experience with a strong grasp of helpdesk fundamentals-ticketing systems, SLA adherence, and performance metrics; ITIL Foundation knowledge or certification preferred. + Advanced capabilities using Microsoft products including Outlook, Excel, Word, PowerPoint, Teams and SharePoint. + Knowledge of modern workplace technologies, Windows system administration, M365 administration, enterprise backup and recovery, and system performance monitoring tools; agile project management techniques. + Strategic thinker with strong problem-solving abilities, capable of managing multiple priorities under pressure while maintaining attention to detail. + High emotional intelligence and discretion, with a proactive and customer-focused approach to anticipating needs and resolving issues. + Self-starter with initiative and adaptability, thriving in fast-paced, diverse environments and contributing effectively to team success. + Preferredexperience with SOX compliance, enterprise desktop management, mobile device management, cybersecurity tools and incident response processes. + Competencies: [Examples may include:] Leadership, Interpersonal Skills, High Emotional Intelligence, Independent Judgement, Teamwork / Collaboration, Verbal & Written Communication, Project Management, Microsoft Office Suite, Attention to Detail, Adaptability + Working Conditions: This is a hybrid position based in Xeris' Chicago office. A minimum of three days per week in the office is required. On-site requirements may change at management's discretion.Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $75,000 to $110,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process_ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _IT Service Desk Lead_ **ID** _2025-2300_ **Category** _IT_ **Type** _Full-Time_

The Scientist I, Analytical Development position is responsible for the development and implementation of analytical characterization methods for a range of pharmaceutical dosage forms to support formulation, process, and specification development. This position collaborates with product development scientists in developing therapeutic drug products utilizing the company's proprietary XeriSol and XeriJect platform technologies. This position also supports Quality Control and CMC functions in establishing product specifications, stability programs, material qualification, method validation, method transfer, and process validation. **Responsibilities** + Develop and perform specific and selective chromatographic methods (i.e. HPLC, UHPLC, LCMS) for use in characterizing prototype pharmaceutical formulations. Where applicable, methods should be compatible with mass selective/mass spectroscopic detection. + Collaborate with formulation and analytical scientists in the Product Development group to design appropriate stability programs for drug products. + Proficiently configure, operate, and maintain analytical instruments including liquid chromatography systems (HPLC), Karl Fischer titrators, and particle size analyzer. + Keep current with relevant literature and industry standards as applicable to research areas. + Implement analytical procedures according to compendial monographs and standards (USP, EP). + Perform the duties as required for reference standard programs, instrument maintenance and calibration, and drug product stability programs + Collect, analyze, and interpret analytical instrument data while maintaining detailed laboratory records. + Draft Standard Operating Procedures (SOPs) for laboratory equipment operation and maintenance. + Manage external contract laboratories for method development, transfer, and QC testing. + Assume a lead SME role in analytical chemistry related team roles and responsibilities (internal and external projects). + Prepare development reports and contribute to regulatory submissions, including IND and NDA documentation. + Adhere to departmental budgets and spending guidelines. **Qualifications** + A Bachelor of Science degree with 3+ years of method development experience in an industrial pharmaceutical laboratory OR + MS / PhD in analytical chemistry with 1+ years of relevant industrial pharmaceutical experience. + Alternatively, a Ph.D. with relevant academic research experience may substitute for some industrial experience. + An appropriate understanding of method development, method validation, and method transfer principles. + Hands-on experience and expertise with HPLC or UHPLC is a must. + Demonstrated understanding of modern chromatographic theory, particularly chromatographic methods focused on Peptides, Proteins and Biologics. + Familiarity with GMP/GLP environments and understanding of FDA and ICH guidelines is a plus. + Ability to work effectively both independently and collaboratively within a team environment. + Prior experience with successful regulatory submissions (IND/NDA/BLA) and commercial method support is a plus. + Developing study protocols and reports with meticulous attention to record accuracy and completeness. + Working knowledge of Microsoft Productivity software (Excel, Word, PowerPoint, etc.) and Agilent OpenLab. + Statistical analysis software such as GraphPad Prism, MiniTab, and JMP is a plus. + Competencies: Teamwork & CollaborationAttention to Detail, Self-Starter, Analytical skills, Problem Solving, Organizational skills, Adaptability, Professionalism, Strong Written and Verbal Communication skills. + Working Conditions: + Must be able to stand for extended periods of time. + Must be able to lift 25 lbs. or more. + Adequate vision (corrected or uncorrected) to read fine instruments such as calipers, instrument displays, etc., and perform visual inspection for defects. + Position works with potentially hazardous chemicals and active pharmaceutical ingredients. May require periodic evening and weekend work as needed to meet program deadlines. + Position may include periodic travel (domestic and international). + _This position is based in Xeris' Chicago office and requires five days per week on-site. On-site requirements may change at management's discretion._ _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-ONSITE _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $80,000 - $120,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for commission and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process._ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Scientist I, Analytical Development_ **ID** _2025-2314_ **Category** _Product Development_ **Type** _Full-Time_

The Senior Financial Analyst is a key member of the Finance team responsible for providing financial support and analysis focused on inventory management, manufacturing expense and product cost. This person will be the lead business partner to supply chain, technical operations, and manufacturing to ensure accurate tracking and forecasting of manufacturing costs, inventory balances, and product margins. This role combines strong analytical and financial modeling skills with a solid understanding of biopharmaceutical supply chain and manufacturing dynamics. **Responsibilities** + Financial Planning & Forecasting + Lead the annual budgeting and quarterly forecasting processes across commercial and lifecycle management manufacturing teams + Prepare and update detailed expense templates and forecasts; consolidate departmental inputs for review + Collaborate with FP&A leadership to ensure all financial assumptions are accurate and consistent with company objectives + Present financial data to all levels of the organization to highlight important drivers and metrics + Support cash balance projection process through calculation of cash flow impacts related to procurement and production of commercial products + COGS planning & analysis + Support quarterly and annual COGS forecasting processes for commercial products + Develop and maintain cost models to project product gross margins under various volume and pricing scenarios + Analyze actual vs. forecasted manufacturing costs, including material, labor, and overhead variances + Provide insights into COGS trends and drivers for management and investor reporting + Partner with Accounting to lead standard cost setting process leveraging information contained in supplier contracts and production forecasts + Inventory planning & management + Collaborate with Supply Chain and Technical Operations to track and forecast inventory levels across raw materials, WIP, and finished goods + Monitor inventory obsolescence, write-offs, and production yields, providing timely financial impact assessments, including proactive tracking and communication of risks and opportunities + Support monthly close activities by reconciling inventory balances and COGS entries with Accounting and prepare analysis on key variance drivers + Help develop and refine inventory reporting tools to improve visibility and accuracy + Business Partnering + Act as a financial partner to Supply Chain, Manufacturing, and Quality functions. + Support budgeting and expense tracking for internal manufacturing and external contract manufacturing organizations (CMOs). + Assist with financial evaluations of supply agreements, purchase requests, production decisions, and capacity planning initiatives + Modeling & Systems Support + Support the FP&A team in maintaining accurate COGS and inventory components within the corporate financial model + Contribute to process improvements to increase forecasting efficiency and reporting quality, including supporting FP&A system implementation and maintenance **Qualifications** + Bachelor's Degree in Finance, Accounting, Supply Chain Management or a related field + 3-5 years of experience in FP&A or corporate finance, ideally within pharmaceuticals, biotech, life sciences, or manufacturing + Advanced Excel and financial modeling skills + Familiarity with FP&A systems + Strong analytical, organization, presentation and communication skills + Ability to manage multiple priorities and meet deadlines in a fast-paced environment + Competencies: Methodical, Detail-oriented, Interpersonal skills, Written and Verbal Communication skills, Strategic, Professionalism, Organizational skills, Self-directed, Teamwork, Adaptability + Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. _This is a hybrid role based in Xeris' Chicago office and requires a minimum of three days per week in the office. On-site requirement may change at management's discretion._ _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $75,000 to $100,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process_ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Senior Financial Analyst_ **ID** _2025-2313_ **Category** _Finance_ **Type** _Full-Time_

The Manager of Quality Control position is a hands-on role providing support for all aspects of Quality Control for clinical and commercial products. The position will provide expertise in drug substance (API), drug product and device analytical testing. Specifically, the role will provide support to release and stability testing of products, including providing support to investigations related to OOS/OOT results, nonconformances, deviations and other product associated incidents. The role will also oversee or support stability programs related to mid-stage clinical to commercial programs. The position will ensure timely and appropriate analytics activities to meet project target profiles and ICH, USP, FDA, and EMA standards. The Manager will effectively communicate results and issues to peers and management with excellent professional standards. **Responsibilities** 1. Manager Quality Control operations at contract sites (CDMO, CMO, Laboratories, etc.). Responsibilities include, but may not be limited to: - Managing contract relationships - Managing Contract Approval Forms, Purchase Orders and updates when required - Participating in vetting and selecting appropriate contract testing labs through the Xeris supplier management process - Supporting material qualification processes - Supporting the coordination of testing of raw, intermediate, and final product through the global supply chain - Managing analytical methods validation and transfer to/from contract testing labs - Overseeing release and stability testing operations at contract sites - Ensuring timely and appropriate analytics activities to meet project target profiles and ICH, USP, FDA, and EMA standards - Manage/validate SLIMstat software and trend manufacturing/stability data - Participating in the preparation of analytical, testing, and specification sections of regulatory submissions and communications - Adhering to CMC/QC budgets 2. Support Mid/late Stage clinical and commercial stability programs. Responsibilities include, but may not be limited to: - Supporting the clinical stability programs for Xeris mid-to-late stage products - Supporting the commercial stability programs for Xeris commercial products - Managing stability sample storage and testing at contract sites - Managing API retain and reference standard storage - Participating in the preparation of stability sections for drug substance and drug product sections of regulatory submissions **Qualifications** - Bachelor's/Master's degree in biology, chemistry, or similar discipline and 5+ years of experience working with pharmaceuticals/biopharmaceuticals, or Ph.D. and 5+ years' experience - A minimum of 5 years in a supervisor or manager role in a GMP pharmaceutical/biopharmaceutical environment, including knowledge of analytical requirements for clinical-phase and commercial products - Experience in Quality Controls and analytical method validation operations - Solid understanding of Quality Systems in support of investigations and quality events - Ability to effectively work with R&D scientists, CMC engineers, Supply Chain, Regulatory Affairs, and Quality Assurance functions - Proficient with Microsoft Word, PowerPoint, Outlook, and Excel, as well as web-based software for various applications - Experience in the use and application of statistical software. For example, SLIM, JMP, etc. -Competencies: Teamwork & Collaboration, Attention to Detail, Self-Starter, Analytical skills, Problem Solving, Organizational skills, Project Management, Adaptability, Professionalism, Written and Verbal Communications, Presentation skills -Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. This is a hybrid role based in Xeris' Chicago office and requires a minimum of three days per week in the office. On-site requirements may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. \#LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $110,000 to $160,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization. **Job Locations** _US-IL-Chicago_ **Title** _Manager, Quality Control_ **ID** _2026-2330_ **Category** _Quality Control_ **Type** _Full-Time_

Support all functions of the pharmaceutical supply chain for all commercial products. Ensure product is manufactured in a quality manner under cGMP's and available for sale based on commercial forecasts. Ensure inventory and supplies are available at every point within the supply chain to meet production schedule. The Engineer I will provide a broad understanding of the manufacturing supply chain from drug substance manufacturing through commercial packaging and working within a matrixed organization. The Engineer I / II will assist with planning and execution of routine technical assignments and demonstrates firm understanding of relevant pharmaceutical regulations related to cGMP manufacturing. Responsibilities Support manufacturing operations at Contract sites (CMOs, etc.). Responsibilities include, but may not be limited to: Assist in commercial production planning Support colleagues in the day-to-day manufacturing activities on a routine basis to ensure commercial supply Helps with logistics activities such as quotes, invoices, inventory management and shipment of products and intermediates Frequently interacts with other functional peer group managers and CMOs to support the commercial manufacturing or development activities Accurately collects / performs data mining and appropriately records / trends observations Aid in the review of GMP batch records, work instructions, SOPs, deviations, CAPAs, or other required documents for cGMP operations Collaborate with other functions such as Device Development, Quality Assurance, Quality Control, Regulatory, and Finance Qualifications Bachelor's degree required, master's degree preferred in Engineering or relevant Supply Chain, Scientific, or equivalent degree with 3 to 5 years of experience working in pharmaceuticals Minimum 3 years of experience in a GMP pharmaceutical/biopharmaceutical environment with sterile drug product manufacturing Must have strong computer skills (including all Microsoft Office), Analytics, Technical Writing, Scheduling, Inventory Management Skills preferred: Data Management, Manufacturing/Supply Chain background Competencies: Teamwork & Collaboration, Attention to Detail, Self-Starter, Analytical skills, Problem Solving, Organizational skills, Project Management, Adaptability, Professionalism, Written and Verbal Communications, Presentation skills Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Travel may be required up to 20% at times to CMOs and CSPs location. Periodic overnight travel may occur for work. This position is based in Xeris' Chicago office. A minimum of four days per week on site is required. On site requirement may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $80,000 to $110,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

The Regional Business Director (RBD) is accountable for providing leadership, direction, and developmental guidance to a team of Territory Business Managers (TBMs) in pursuit of commercial objectives. Reporting to the Area Vice President of Sales, the RBD will participate in the development and execution of strategic and tactical plans in order to meet and exceed sales goals and business objectives while remaining aligned with Xeris' values. Travel requirements will vary by region but will minimally be 50%. This territory covers the following areas: Minneapolis, MN; Des Moines, IA: Omaha, NE; St. Louis, MO; Kansas City, MO; Wichita, KS; Tulsa, OK; Oklahoma City, OK; Denver, CO; and Salt Lake City, UT. Responsibilities Work closely with management to establish corporate objectives specific to assigned region Deliver on corporate objectives specific to region. With team and business partner input, develop, evolve, and execute regional business plans. Eliminate or minimize barriers to progress, engaging the VP of Sales when appropriate regarding marketplace trends, business opportunities & threats, competitive information, and recommendations for addressing each. Leverage internal expertise to maximize field impact. Work with the Channel/Trade & Market Access Teams and other Regional Business Directors, to develop region-specific strategies for managed care accounts and reimbursement clarity. Manage regional budget and resource allocations to maximize return on investment. Hire and develop Territory Business Managers (TBMs) who will effectively advance Xeris' business in alignment with strategic goals Identify and attract TBMs who will excel in the diabetes market (endo, ped. Endo, primary care, local diabetes chapters, hospitals, LTC, etc.). Lead, teach, motivate and inspire a team of TBMs to achieve / exceed sales objectives in their assigned sales territory. Engage TBMs frequently, including regular field visits & business reviews, listening to and coaching them to identify and maximize opportunities and leverage successes. Foster a solution-orientation throughout the region. Provide verbal and written feedback - positive and developmental - to foster a positive and productive environment of achievement that embraces personal accountability. Recognize and reward strong performers, and coach employees performing below expectations, holding them accountable for improvement. Develop, lead, and facilitate effective team sales meetings. Create a face to the internal and external customer that demonstrates Xeris' commitment to bringing value and solutions to the customers and patients we serve. Collaborate with peers, marketing and training personnel to share information and implement regional initiatives/strategies. Professionally and ethically represent Xeris to external customers and foster their respect by demonstrating our commitment to advancing patient care and outcomes. Professionally and ethically represent Xeris internally and foster professionalism within, among, and beyond the team of TBMs. Pre-launch: Engagement and profiling of key regional accounts (physicians, payers, PBMs, hospitals and other alternate site customers); post-launch: engagement with key accounts. Create, build and maintain relationships and regular communication with physicians and key thought leaders. Qualifications Bachelor's Degree in the Health Sciences, Business/Marketing, Accounting, or related field; advanced degree preferred. 8-10 years in bioscience commercial positions, including some but not limited to the following: sales representative, hospital representative, sales trainer, district manager, marketing manager, regional account manager, government affairs, and sales operations. 3-5 years previous leadership experience required. A valid, US State-issued driver's license is required. Recent experience managing key accounts (or leading teams doing the same) with experience in the diabetes market highly desirable. Ability to influence and drive business performance through establishment and management or key performance metrics. Ability to identify and facilitate business risk/issue mitigation and resolution. Strong track record leading teams demonstrating the ability to coach and mentor others to reach or exceed organization goals. Ability to hold others accountable to organizational goals and take action when team members are not meeting expectations. Competencies: Leadership skills, Strategic thinking, Organizational skills, Self-directed, Strong Written and Verbal Communication skills, Decision-making skills, Customer Service focus, Analytical skills, Teamwork & Collaboration. Position may require periodic evening and weekend work, as necessary to fulfill obligations. Frequent travel up to 50% domestically. Position requires vehicle travel, as necessary. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-REMOTE As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $180,000 to $240,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for commission and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization. Direct Employers Posting: Minneapolis, MN; Des Moines, IA: Omaha, NE; St. Louis, MO; Wichita, KS; Tulsa, OK; Denver, CO; Salt Lake City, UT.

Support all functions of the pharmaceutical supply chain for all commercial products. Ensure product is manufactured in a quality manner under cGMP's and available for sale based on commercial forecasts. Ensure inventory and supplies are available at every point within the supply chain to meet production schedule. The Engineer I will provide a broad understanding of the manufacturing supply chain from drug substance manufacturing through commercial packaging and working within a matrixed organization. The Engineer I / II will assist with planning and execution of routine technical assignments and demonstrates firm understanding of relevant pharmaceutical regulations related to cGMP manufacturing. **Responsibilities** Support manufacturing operations at Contract sites (CMOs, etc.). Responsibilities include, but may not be limited to: + Assist in commercial production planning + Support colleagues in the day-to-day manufacturing activities on a routine basis to ensure commercial supply + Helps with logistics activities such as quotes, invoices, inventory managementand shipment of products and intermediates + Frequently interacts with other functional peer group managers and CMOs to support the commercial manufacturing or development activities + Accurately collects / performs data mining and appropriately records / trends observations + Aid in the review of GMP batch records, work instructions, SOPs, deviations, CAPAs, or other required documents for cGMP operations + Collaborate with other functions such as Device Development, Quality Assurance, Quality Control, Regulatory, and Finance **Qualifications** + Bachelor's degree required, master's degree preferred in Engineering or relevant Supply Chain, Scientific, or equivalent degree with 3 to 5 years of experience working in pharmaceuticals + Minimum 3 years of experience in a GMP pharmaceutical/biopharmaceutical environment with sterile drug product manufacturing + Must have strong computer skills (including all Microsoft Office), Analytics, Technical Writing, Scheduling, Inventory Management + Skills preferred: Data Management, Manufacturing/Supply Chain background + Competencies: Teamwork & Collaboration, Attention to Detail, Self-Starter, Analytical skills, Problem Solving, Organizational skills, Project Management, Adaptability, Professionalism, Written and Verbal Communications, Presentation skills + Working Conditions:Position may require periodic evening and weekend work, as necessary to fulfill obligations. Travel may be required up to 20% at times to CMOs and CSPs location. Periodic overnight travel may occur for work. This position is based in Xeris' Chicago office. A minimum of four days per week on site is required. On site requirement may change at management's discretion. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $80,000 to $110,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process_ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Engineer I, Commercial Manufacturing_ **ID** _2025-2307_ **Category** _Technical Operations_ **Type** _Full-Time_

The Associate Medical Director will act as the Medical Monitor for Xeris clinical trials, collaborating with cross-functional study teams on clinical trial strategy, design and execution. In this role, the individual will oversee study conduct and safety monitoring for assigned trials, spanning Phases 1 through 3, and may also contribute to selected projects across multiple clinical development programs. **Responsibilities** + Provides project physician support to clinical study teams during the execution of clinical research studies, including but not limited to protocol development, electronic Case Report Form (eCRF) development, therapeutic area training, protocol queries, patient eligibility determination, clinical/safety data review, and clinical summary report generation. + Serves on cross-functional teams for assigned trials, working with other team members to achieve efficient, high-quality study execution. + Contributes to the preparation of regulatory documents in support of regulatory submissions, including but not limited to clinical section of Investigational New Drug's (IND) application and Clinical Trial Agreement (CTA), IND safety reports and annual reports for assigned trials, responses to regulatory authorities and Ethics Committees/Institutional Review Boards , and other documents as appropriate. + Provides scientific and clinical input to study-related documents and analysis plans [e.g. informed consent forms (ICF), statistical analysis plans (SAP), clinical study reports (CSR)]. + Performs other duties as assigned related to other aspects of Clinical Research. + Represents Xeris at clinical sites during studiesand in external reporting of study results. + Up to 30% global travel **Qualifications** + Medical Doctor (MD), Doctor of Osteopathy (DO), or non-US equivalent of MD degree with relevant therapeutic specialty in an academic or hospital environment. + Board certification/eligibility Internal Medicine, Endocrinology or another relevant medical field, is highly desired + Ability to run a clinical research study with minimal supervision + Clinical trial experience in the pharmaceutical industry, academia, or equivalent is desired + Knowledge of clinical trial methodology, regulatory and compliance requirements governing clinical trials + Excellent oral and written communication skills + Ability to work collaboratively in a fast moving, team-based matrix environment and to function independently as appropriate + This is a hybrid position based in Xeris' Chicago office and a minimum of three days per week on-site is required. On-site requirements may change at management's discretion. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-HYBRID _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $200,000 to $260,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process._ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Associate Medical Director_ **ID** _2025-2297_ **Category** _Medical Affairs_ **Type** _Full-Time_

The Senior Manager, Reimbursement Access will play a critical role in ensuring appropriate patient access to Xeris products by leading the Reimbursement Access team, shaping national access strategies, and supporting operational excellence across the function. The incumbent must have deep experience in reimbursement, patient access, and healthcare provider support services, and leadership experience that includes driving the execution of complex operations while developing a high performing team of Reimbursement Access Managers. Covers CA, WA, OR, NV, and ID including: Los Angeles, CA: San Diego, CA; San Jose, CA; San Francisco, CA; Seattle, WA; Spokane, WA; Portland, OR; Las Vegas, NV; Coeur d'Alene, ID. Responsibilities Team Leadership & Talent Development Identify, recruit, onboard, and develop a high-performing team of Reimbursement Access Managers (RAMs) across key geographies. Provide coaching, mentorship, and performance management to drive effectiveness and professional growth. Lead field-based access teams to execute patient support strategies that improve access and affordability for patients. Reimbursement Strategy & Execution Collaborate with Patient Access leadership to design and implement innovative reimbursement access strategies that align with product and company goals. Analyze access barriers and develop field-based solutions to improve access to therapies for rare disease patients. Partner with internal teams (Commercial, Medical Affairs, Legal, Compliance) to ensure alignment and seamless execution of access initiatives. Operational Excellence Assist in developing standard operating procedures (SOPs), metrics, and reporting tools to evaluate and optimize the effectiveness of the Reimbursement Access function. Drive continuous improvement initiatives to ensure the highest standards of patient access and compliance. Monitor and assess reimbursement trends, payer coverage, and changes in access environment; provide recommendations to senior leadership. Stakeholder Engagement Serve as a strategic liaison between internal stakeholders and field reimbursement teams to ensure market and patient needs are addressed. Provide insights from the field to inform leadership decisions on payer strategy, patient affordability programs, and other access-related initiatives. Represent the company at relevant industry meetings, conferences, and with key external stakeholders as needed. Qualifications Bachelor's degree in business, healthcare, or related field (advanced degree preferred). Minimum of 7 years of experience in market access, reimbursement, patient services, or related pharmaceutical roles. Prior leadership experience managing field reimbursement teams strongly preferred. In-depth understanding of the reimbursement landscape including buy-and-bill, specialty pharmacy, payer dynamics, copay assistance, and HUB services. Experience in rare diseases or specialty biologics/therapies. Demonstrated ability to lead cross-functional initiatives in a fast-paced, entrepreneurial environment. Willingness to travel (up to 30%) to support field teams and stakeholders. Competencies: Leadership, Presentation skills, Written and Verbal Communications, Analytical skills, Problem Solving, Teamwork & Collaboration, Customer Service focus, Adaptability, Professionalism A valid, US state-issued driver's license is required as occasional driving to client locations is a core requirement of this position. Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. Ability to Travel up to 30%. Travel may include air and ground travel to HCP locations, and company meetings The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-REMOTE As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $130,000 to $220,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for commission and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization. Direct Employers Posting: Los Angeles, CA: Seattle, WA; Portland, OR; Las Vegas, NV; Coeur d'Alene, ID.

The Senior Counsel, Clinical Development is a key role responsible for supporting all Xeris clinical development activities, with an initial focus on Xeris's lead pipeline asset. The ideal candidate has significant experience providing legal support for large-scale clinical trials, including drafting and negotiating a wide variety of trial-related agreements. This is an excellent opportunity to contribute to a high-impact legal function on a part-time basis. Responsibilities Provide direct legal support to Xeris' clinical development team for all clinical development matters, including those relating to the pivotal Phase 3 trial of Xeris' XP-8121 product candidate for the treatment of adults with hypothyroidism and any associated trials (e.g., open-label extension). Draft, review, and negotiate a broad range of clinical trial documents and contracts, including clinical trial site agreements, informed consent forms, clinical service provider agreement(s) and amendments, and indemnification agreements. Coordinate with CRO(s) and Xeris' clinical development team with respect to site contracting. Provide legal guidance on regulatory and compliance issues related to clinical trials, including data privacy and CRO/site/investigator compliance. Help manage outside counsel and legal vendors related to clinical trial activities. Leverage contract law expertise to provide support in other areas as needed and as workload allows Qualifications Juris Doctor (JD) degree from an accredited law school required Is a member in good standing of a state bar association Minimum of 5 years supporting large-scale, pivotal clinical trials at a mid- to large-sized law firm and/or established pharmaceutical company Capable of handling multiple and competing workloads with changing priorities to meet deadlines Able to work independently but know when to involve others or ask for guidance Can work effectively with all levels of the organization Competencies: Attention to Detail, Highly Organized, Strong Interpersonal Skills, Team Player, Self-Starter, Discrete, Excellent Verbal and Written Communication skills, Customer Service, Time Management Working Conditions: This is a part-time position, with an expectation of 30 hours of work per week Position may require periodic evening and weekend work, as necessary to fulfill obligations. This is a remote position, with an expectation of periodic attendance in Xeris' Chicago headquarters. On-site requirements may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-REMOTE As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $190,000 to $240,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

Xeris is seeking an experienced Director of Formulation Development to lead and manage a team developing innovative dosage forms and drug delivery systems. Reporting to the Sr. Director, Formulation Development, this role will provide strategic and technical leadership across formulation activities while also directing complex projects that are critical to advancing the company's product pipeline. As an expert in the areas of preformulation and formulation development studies, drug delivery technologies, and product development, this position will be responsible for providing guidance, oversight, and mentoring to a team of scientists. This role will anticipate potential developmental challenges and implement mitigation strategies to reduce program risk. **Responsibilities** + Lead and manage a team of scientists in the development and execution of complex formulation projects for injectable small molecules, peptides, and proteins using Xeris' novel proprietary formulation platforms. + Provide strategic direction and guidance to the formulation development team on all aspects of injectable small molecule, peptide, and protein formulations, including process development, characterization, scale-up, tech transfer and manufacturing support. + Lead high throughput screening of excipients, selection of primary drug container closure systems, identification of degradation pathways, and development of stable formulations. + Lead the development and implementation of novel formulation strategies for injectable products, including long-acting formulations, sustained release formulations, and targeted delivery systems. + Demonstrate a thorough understanding of relevant technical/scientific literature, standard procedures, and pharmaceutical regulations relevant to the programs. + Develop and implement innovative methods for characterization and stability testing of injectable biologics. + Drive the development of robust and scalable manufacturing processes for injectable products. + Identify and mitigate technical risks associated with formulation development and manufacturing. Anticipate manufacturability challenges associated with parenteral drug product development. + Develop and manage project budgets and timelines, ensuring efficient and on-time completion of projects. + Communicate effectively with cross-functional teams (e.g., R&D, Regulatory, Manufacturing) to ensure seamless product development. + Provide guidance on quality aspects across regulatory filings related to specifications, acceptance criteria, and stability protocols. + Cultivate partnerships by serving as lead point of contact with contract manufacturing organizations and external collaborators. + Ensure compliance with all relevant regulatory requirements for injectable products, including ICH guidelines and FDA regulations. + Contribute to the preparation and submission of regulatory documentation, including INDs, NDAs, and BLAs. + Provide expert technical support during regulatory inspections and audits. + Build a high performing team through mentoring, goal setting, and supporting the continuing education of junior staff. + Contribute to the development of internal training programs and seminars related to formulation science and technology. + Write and review study protocols and reports (both formal and informal) to support product development studies and regulatory filings. + Stay current with the latest scientific literature and present findings at industry conferences and events. + Identify and evaluate emerging technologies and trends in the field of injectable formulation development. + Develop and implement strategic initiatives to improve the efficiency and effectiveness of the formulation development process. **Qualifications** + Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering or related discipline. + A minimum of 10 years in pharmaceutical development, with increasing management responsibility. + Familiarity with regulatory requirements for pharmaceutical development. + Passion for innovation and scientific discovery, developing junior staff, and advancing healthcare through novel medicines. + Knowledge and proficiency using experimental design and statistical analysis software (e.g., JMP / MiniTab / GraphPad Prism). + Competencies:Attention to Detail, Independent Judgement, Teamwork & Collaboration, Self-Starter, Adaptability, Professionalism, Written & Verbal Communication skills, Functional Leadership, Problem-Solving skills, Project Management skills. + Working Conditions: + Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. + Must be able to stand for extended periods of time. Must be able to lift 25 lbs. or more. + Adequate vision (corrected or uncorrected) to read fine instruments such as instrument displays, etc., and perform visual inspection for defects. + This position is based in Xeris' Chicago office and requires five days per week on-site to ensure oversight and leadership of the laboratory team. + Position works with potentially hazardous chemicals and active pharmaceutical ingredients. + Domestic and/or international travel up to 10% may be required. _The level of the position will be determined based on the selected candidate's qualifications and experience._ \#LI-ONSITE _As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors._ _The anticipated base salary range for this position is $175,000 - $250,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for commission and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process._ _NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization._ **Job Locations** _US-IL-Chicago_ **Title** _Director, Formulation Development_ **ID** _2025-2291_ **Category** _Product Development_ **Type** _Full-Time_

The Associate Director, Biostatistics and Statistical Programming will drive biostatistical activities, performed primarily by vendors, in support of project timelines and budgets related to drug product development at Xeris. The individual will contribute to study design, protocol development, case report form development, clinical study reports, and exhibits for other reports and presentations. Responsibilities Conducts basic statistical analysis of study data with minimal supervision according to a statistical analysis plan to generate results and insights used to support study findings. Applies moderately advanced statistical methods, which may include simulation models and other statistical programming as needed, with guidance. Generates sample size and power calculations and randomizations. Oversees the review of statistical documents and operational activities outsourced to CROs ensuring adherence to cost, timeline, and data quality requirements to ensure that the analysis plans use the most appropriate statistical methods and that the data displays such as tables/figures/listings are accurate and complete. Programs or independently validates key study results to support interpretation of data. Provides statistical programming support to other clinical studies or regulatory submissions where another biostatistician is assigned as the sponsor lead. Works closely with Data Management by providing input to data management-related documents and assisting with data review and cleaning activities, as needed. Ensures compliance of data packages to regulatory requirements and CDISC and industry standards. Assists in the development of abstracts, manuscripts, presentations for scientific congresses. Closely collaborates and participates in knowledge sharing with other team members including non-statisticians to assist with interpretation and understanding of results. Qualifications MS/MPH degree in biostatistics, statistics, or epidemiology A minimum of six years of clinical trial experience as a statistician and/or statistical programmer in the pharmaceutical, biotech, or CRO industry Experience in Phases I-III of the clinical drug development process Knowledge and basic understanding of statistical concepts and techniques commonly applied to the analysis of data from clinical trials and the ability to tackle from basic to moderately complex statistical or data issues Basic understanding of real-world data and observational studies. SAS programming experience required, R experience is a plus Working knowledge of CDISC standards Prior use and implementation of sample size and power calculation software (e.g., nQuery and PASS) preferred Working knowledge of EDC systems Competencies: Attention to Detail, Organizational skills, Adaptability, Multi-Tasking, Strong Written & Verbal Communication skills, Teamwork & Collaboration, Critical Thinking, Problem Solving, Presentation Skills Working Conditions: This is a hybrid position based in Xeris' Chicago office. A minimum of three days per week on-site is required. On-site requirement may change at management's discretion. Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $140,000 to $240,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

Reporting directly to the Vice President of Clinical Development, the Medical Writer will be responsible for leading and executing all medical writing activities supporting Xeris' clinical programs. The individual will have a strong scientific background, exceptional writing skills, and a proven ability to translate complex clinical and scientific data into clear, accurate, and regulatory-compliant documents tailored to diverse audiences. Responsibilities Develop and author a broad range of clinical and regulatory documents, including but not limited to: clinical study protocols, investigator brochures (IBs), clinical study reports (CSRs), and sections of regulatory submissions (e.g., IND, NDA, etc.). Ensure accuracy, clarity, consistency, and compliance with internal standards, applicable regulatory guidelines (e.g., ICH, FDA, EMA), and company SOPs. Collaborate cross-functionally with colleagues in Clinical, Regulatory Affairs, Medical Affairs, and other internal stakeholders to gather relevant data and ensure consistency of messaging across documents. Translate highly technical and statistical information into clear, concise content suitable for a wide variety of audiences including regulators, healthcare professionals, and non-scientific business leaders, as required. Contribute to the development of communication materials, including slide decks, manuscripts, abstracts, and presentations, to support internal and external scientific communications. Maintain document quality control through proofreading, editing, and adherence to templates, style guides, and version control procedures. Manage timelines and priorities for multiple projects simultaneously, ensuring timely and accurate delivery of high-quality documents. Provides detailed medical editing review of draft and final documents prepared by other writers before internal or external distribution. This includes both copy editing and content review. Ensures document content and style adheres to FDA/EMA or other appropriate regulatory guidelines and complies with departmental SOPs and style guidelines. Performs literature searches and reviews as necessary to obtain background information and provide literature references. Provide input on processes, templates, and other business needs within the medical writing function. Coordinate and/or manage review cycles to triage, incorporate, and resolve team comments, and lead discussion on document revision and finalization for both internally written and outsourced documents. Serve as a point person for medical writing guidance and document-related problem resolution. Qualifications Bachelor's degree in Life Sciences or a related field is required; advanced degree (PhD, PharmD, or MS) strongly preferred. Minimum of 5 years of medical writing experience in the pharmaceutical, biotechnology, or clinical research industry, with a focus on late-stage clinical development (Phase 3). Demonstrated experience in writing regulatory submission documents in compliance with regulatory agency guidelines. Proficiency in Microsoft Office Suite and familiarity with document management systems and version control tools. Competencies: Attention to Detail, Organizational skills, Adaptability, Multi-Tasking, Strong Written & Verbal Communication skills, Independent Judgement, Cross-Team Collaboration, Critical Thinking, Problem Solving Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. This is a hybrid position located in Xeris' Chicago office and requires three days per week on-site. On-site requirement may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $75,000 to $150,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

The IT Service Desk Lead is responsible for overseeing daily IT support operations, ensuring efficient service delivery, and driving continuous improvement across the helpdesk function in a Microsoft centric environment. This role serves as a key liaison between end-users and technical teams, ensuring secure, scalable, and premium support for both office and field-based employees. Responsibilities Lead daily IT support operations across office and field teams, ensuring timely resolution of issues and minimal business disruption, utilizing ITIL best practices. Serve as the primary escalation point for complex technical problems and high-priority service requests. Own and evolve ITSM processes (incident, service request, change and problem), document repeatable procedures, and lead support-related projects. Incident Management - Lead incident response efforts by prioritizing and resolving IT issues swiftly, coordinating with support teams to minimize disruption, meet SLAs, and drive continuous improvement through analysis and reporting. Service Request Management - Manage and optimize the service request lifecycle, ensuring timely fulfillment, process efficiency, and alignment with ITIL best practices of user requests in alignment to enhance user experience and operational performance. Change Management - Coordinate and oversee change management activities, ensuring proper assessment, approval, and communication of changes to minimize risk and disruption to IT services. Problem Management - Drive problem management processes by identifying recurring issues, performing root cause analysis, and implementing long-term solutions to improve service stability and reduce incident volume. Lead and report to management on a regular cadence. Project Management - Lead support center projects, integrating new technologies and driving successful implementation. Asset Management - Manage the lifecycle of user-facing technology, maintain accurate asset inventory, and enforce IT security protocols. Take ownership of support issues, engaging other internal / external expertise as required. Ability to communicate complex technical information to all stakeholders, including those who do not have a technical background. Continuously educate employees and equip them with essential IT tools and best practices. Qualifications Associate or bachelor's degree in information technology or equivalent work experience preferred 5+ years of progressive experience in IT support/helpdesk roles Proven supervisory experience with a strong grasp of helpdesk fundamentals-ticketing systems, SLA adherence, and performance metrics; ITIL Foundation knowledge or certification preferred. Advanced capabilities using Microsoft products including Outlook, Excel, Word, PowerPoint, Teams and SharePoint. Knowledge of modern workplace technologies, Windows system administration, M365 administration, enterprise backup and recovery, and system performance monitoring tools; agile project management techniques. Strategic thinker with strong problem-solving abilities, capable of managing multiple priorities under pressure while maintaining attention to detail. High emotional intelligence and discretion, with a proactive and customer-focused approach to anticipating needs and resolving issues. Self-starter with initiative and adaptability, thriving in fast-paced, diverse environments and contributing effectively to team success. Preferred experience with SOX compliance, enterprise desktop management, mobile device management, cybersecurity tools and incident response processes. Competencies: [Examples may include:] Leadership, Interpersonal Skills, High Emotional Intelligence, Independent Judgement, Teamwork / Collaboration, Verbal & Written Communication, Project Management, Microsoft Office Suite, Attention to Detail, Adaptability Working Conditions: This is a hybrid position based in Xeris' Chicago office. A minimum of three days per week in the office is required. On-site requirements may change at management's discretion. Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $75,000 to $110,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

The Scientist I, Analytical Development position is responsible for the development and implementation of analytical characterization methods for a range of pharmaceutical dosage forms to support formulation, process, and specification development. This position collaborates with product development scientists in developing therapeutic drug products utilizing the company's proprietary XeriSol and XeriJect platform technologies. This position also supports Quality Control and CMC functions in establishing product specifications, stability programs, material qualification, method validation, method transfer, and process validation. Responsibilities Develop and perform specific and selective chromatographic methods (i.e. HPLC, UHPLC, LCMS) for use in characterizing prototype pharmaceutical formulations. Where applicable, methods should be compatible with mass selective/mass spectroscopic detection. Collaborate with formulation and analytical scientists in the Product Development group to design appropriate stability programs for drug products. Proficiently configure, operate, and maintain analytical instruments including liquid chromatography systems (HPLC), Karl Fischer titrators, and particle size analyzer. Keep current with relevant literature and industry standards as applicable to research areas. Implement analytical procedures according to compendial monographs and standards (USP, EP). Perform the duties as required for reference standard programs, instrument maintenance and calibration, and drug product stability programs Collect, analyze, and interpret analytical instrument data while maintaining detailed laboratory records. Draft Standard Operating Procedures (SOPs) for laboratory equipment operation and maintenance. Manage external contract laboratories for method development, transfer, and QC testing. Assume a lead SME role in analytical chemistry related team roles and responsibilities (internal and external projects). Prepare development reports and contribute to regulatory submissions, including IND and NDA documentation. Adhere to departmental budgets and spending guidelines. Qualifications A Bachelor of Science degree with 3+ years of method development experience in an industrial pharmaceutical laboratory OR MS / PhD in analytical chemistry with 1+ years of relevant industrial pharmaceutical experience. Alternatively, a Ph.D. with relevant academic research experience may substitute for some industrial experience. An appropriate understanding of method development, method validation, and method transfer principles. Hands-on experience and expertise with HPLC or UHPLC is a must. Demonstrated understanding of modern chromatographic theory, particularly chromatographic methods focused on Peptides, Proteins and Biologics. Familiarity with GMP/GLP environments and understanding of FDA and ICH guidelines is a plus. Ability to work effectively both independently and collaboratively within a team environment. Prior experience with successful regulatory submissions (IND/NDA/BLA) and commercial method support is a plus. Developing study protocols and reports with meticulous attention to record accuracy and completeness. Working knowledge of Microsoft Productivity software (Excel, Word, PowerPoint, etc.) and Agilent OpenLab. Statistical analysis software such as GraphPad Prism, MiniTab, and JMP is a plus. Competencies: Teamwork & CollaborationAttention to Detail, Self-Starter, Analytical skills, Problem Solving, Organizational skills, Adaptability, Professionalism, Strong Written and Verbal Communication skills. Working Conditions: Must be able to stand for extended periods of time. Must be able to lift 25 lbs. or more. Adequate vision (corrected or uncorrected) to read fine instruments such as calipers, instrument displays, etc., and perform visual inspection for defects. Position works with potentially hazardous chemicals and active pharmaceutical ingredients. May require periodic evening and weekend work as needed to meet program deadlines. Position may include periodic travel (domestic and international). This position is based in Xeris' Chicago office and requires five days per week on-site. On-site requirements may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-ONSITE As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $80,000 - $120,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for commission and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process. NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

The Senior Financial Analyst is a key member of the Finance team responsible for providing financial support and analysis focused on inventory management, manufacturing expense and product cost. This person will be the lead business partner to supply chain, technical operations, and manufacturing to ensure accurate tracking and forecasting of manufacturing costs, inventory balances, and product margins. This role combines strong analytical and financial modeling skills with a solid understanding of biopharmaceutical supply chain and manufacturing dynamics. Responsibilities Financial Planning & Forecasting Lead the annual budgeting and quarterly forecasting processes across commercial and lifecycle management manufacturing teams Prepare and update detailed expense templates and forecasts; consolidate departmental inputs for review Collaborate with FP&A leadership to ensure all financial assumptions are accurate and consistent with company objectives Present financial data to all levels of the organization to highlight important drivers and metrics Support cash balance projection process through calculation of cash flow impacts related to procurement and production of commercial products COGS planning & analysis Support quarterly and annual COGS forecasting processes for commercial products Develop and maintain cost models to project product gross margins under various volume and pricing scenarios Analyze actual vs. forecasted manufacturing costs, including material, labor, and overhead variances Provide insights into COGS trends and drivers for management and investor reporting Partner with Accounting to lead standard cost setting process leveraging information contained in supplier contracts and production forecasts Inventory planning & management Collaborate with Supply Chain and Technical Operations to track and forecast inventory levels across raw materials, WIP, and finished goods Monitor inventory obsolescence, write-offs, and production yields, providing timely financial impact assessments, including proactive tracking and communication of risks and opportunities Support monthly close activities by reconciling inventory balances and COGS entries with Accounting and prepare analysis on key variance drivers Help develop and refine inventory reporting tools to improve visibility and accuracy Business Partnering Act as a financial partner to Supply Chain, Manufacturing, and Quality functions. Support budgeting and expense tracking for internal manufacturing and external contract manufacturing organizations (CMOs). Assist with financial evaluations of supply agreements, purchase requests, production decisions, and capacity planning initiatives Modeling & Systems Support Support the FP&A team in maintaining accurate COGS and inventory components within the corporate financial model Contribute to process improvements to increase forecasting efficiency and reporting quality, including supporting FP&A system implementation and maintenance Qualifications Bachelor's Degree in Finance, Accounting, Supply Chain Management or a related field 3-5 years of experience in FP&A or corporate finance, ideally within pharmaceuticals, biotech, life sciences, or manufacturing Advanced Excel and financial modeling skills Familiarity with FP&A systems Strong analytical, organization, presentation and communication skills Ability to manage multiple priorities and meet deadlines in a fast-paced environment Competencies: Methodical, Detail-oriented, Interpersonal skills, Written and Verbal Communication skills, Strategic, Professionalism, Organizational skills, Self-directed, Teamwork, Adaptability Working Conditions: Position may require periodic evening and weekend work, as necessary to fulfill obligations. Periodic overnight travel. This is a hybrid role based in Xeris' Chicago office and requires a minimum of three days per week in the office. On-site requirement may change at management's discretion. The level of the position will be determined based on the selected candidate's qualifications and experience. #LI-HYBRID As an equal employment opportunity and affirmative action employer, Xeris Pharmaceuticals, Inc. does not discriminate on the basis of race, color, religion, sex, gender identity, sexual orientation, national origin, age, disability, veteran status, genetics or any other characteristic protected by law. It is our intention that all qualified applications are given equal opportunity and that selection decisions be based on job-related factors. The anticipated base salary range for this position is $75,000 to $100,000. Final determination of base salary offered will depend on several factors relevant to the position, including but not limited to candidate skills, experience, education, market location, and business need. This role will include eligibility for bonus and equity. The total compensation package will also include additional elements such as multiple paid time off benefits, various health insurance options, retirement benefits and more. Details about these and other offerings will be provided at the time a conditional offer of employment is made. Candidates are always welcome to inquire about our compensation and benefits package during the interview process NOTE: This job description is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.