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The largest CBD company in the U.S. is Charlotte’s Web, with a revenue of $74.13 million.
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As of 2023, the U.S. CBD industry has a market size of $12.8 billion.
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As of 2023, one-third of all Americans have used CBD products.
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The U.S. CBD market is projected to grow at a CAGR of 21.7% through 2028.
Since the legalization of industrial hemp farming in 2018, the CBD market has rapidly evolved, giving rise to a plethora of startups and established businesses. As of 2026, the industry continues to showcase significant growth potential, although it faces challenges such as regulatory hurdles and a saturated market. Consumers are increasingly discerning, prioritizing high-quality CBD products as they become more informed about their choices.
This article presents a comprehensive list of the 15 largest CBD companies in the U.S., ranked by their most recent estimated annual revenue. Discover how these companies are navigating the evolving landscape of the CBD industry.
15 Largest CBD Companies in the United States
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Charlotte’s Web. Boulder, Colorado
2022 Estimated Annual Revenue: $74.13 million
Founded in 2011 by seven brothers aiming to provide relief to those in need, Charlotte’s Web is named after Charlotte Figi, a child whose severe epilepsy was managed with a specially developed strain of CBD. The company’s product lines include CBDMedic and CBD Clinic, which integrate CBD with pharmaceutical ingredients for both over-the-counter and prescription use. Furthermore, Charlotte’s Web engages in philanthropic efforts with various organizations, including Denver Urban Gardens and Children’s Hospital Colorado.
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Gaia Herbs. Brevard, North Carolina
2022 Estimated Annual Revenue: $54.3 million
Established in 1987 in the Blue Ridge Mountains of North Carolina, Gaia Herbs is one of the oldest companies on this list. It specializes in a diverse range of products, including herbal supplements and CBD extracts in liquid and capsule forms, often combining CBD with other herbal ingredients to enhance health benefits.
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Pure Hemp Botanicals. Denver, Colorado
2022 Estimated Annual Revenue: N/A
Pure Hemp Botanicals embraces a mission of sustainability and compassion, providing a variety of vegan and cruelty-free products, including body care, mints, and teas aimed at promoting wellness. They also offer subscription plans and donate a portion of each sale to charitable causes.
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cbdMD. Charlotte, North Carolina
2022 Estimated Annual Revenue: $35 million
Founded in 2015, cbdMD offers a wide range of CBD products including tinctures, gummies, and topicals, and has partnered with various athletes to promote its brand.
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Medical Marijuana, Inc. San Diego, California
2021 Estimated Annual Revenue: $34.1 million
Medical Marijuana, Inc. operates through subsidiaries such as HempMeds and Kannaway, distributing brands like Real Scientific Hemp Oil and Dixie Botanicals. As the first publicly traded cannabis company in the U.S., it has a significant historical footprint in the industry.
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Green Roads. Deerfield Beach, Florida
2020 Estimated Annual Revenue: $33.8 million
With a foundation in pharmaceutical expertise, Green Roads is known for its quality control and diverse product range, including topicals, edibles, and pet products.
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Medterra. Irvine, California
2022 Estimated Annual Revenue: $24.6 million
Medterra, established in 2017, focuses on THC-free products and sources its hemp from Kentucky, ensuring rigorous quality testing for all its offerings.
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CBD American Shaman. Kansas City, Missouri
2022 Estimated Annual Revenue: $24.8 million
As one of the pioneers in the CBD sector, CBD American Shaman has expanded significantly through franchise opportunities and offers a wide array of CBD products, including oils and edibles.
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CV Sciences. San Diego, California
2022 Estimated Annual Revenue: $16.2 million
Founded in 2010, CV Sciences emphasizes research and clinical trials, being the first to receive the FDA’s Generally Recognized as Safe (GRAS) designation for its CBD products.
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CBDistillery – Balanced Health Botanicals. Denver, Colorado
2022 Estimated Annual Revenue: $12.4 million
Since its founding in 2016, CBDistillery has gained a reputation for affordability and accessibility, producing a range of products and offering military discounts.
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NuLeaf Naturals. Denver, Colorado
2022 Estimated Annual Revenue: $10.8 million
NuLeaf Naturals, established in 2014, focuses on high-quality, organic hemp-derived products, using CO2 extraction methods for purity.
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Koi CBD Ltd. Norwalk, California
2020 Estimated Annual Revenue: $8 million
Founded in 2015, Koi CBD emphasizes product traceability and offers a variety of flavors to enhance customer experience.
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Elixinol. Westminster, Colorado
2022 Estimated Annual Revenue: $7.8 million
With a history of working with hemp for 25 years, Elixinol collaborates with professionals to create a range of CBD products, including oils and gummies.
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H.Hemp. Boulder, Colorado
2020 Estimated Annual Revenue: $4 million
Founded by an advocate for mental health, H.Hemp donates a portion of profits to combat opioid and anxiety drug issues, embodying its commitment to honesty and wellness.
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Purespectrum. Evergreen, Colorado
2020 Estimated Annual Revenue: $4 million
Pure Spectrum emphasizes a farmer-first approach, providing safe CBD products to athletes and sponsoring numerous professional sports figures.
Largest CBD Companies FAQ
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Is the CBD industry growing?
Yes, the CBD industry is growing. The U.S. CBD market is projected to grow at a CAGR of 21.7% through 2028.
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What are popular CBD trends?
Popular CBD trends include CBD beverages, skin care products, and dietary supplements. Additionally, CBD edibles continue to gain traction among consumers.
Author
Abby is a writer who is passionate about the power of story. Whether it’s communicating complicated topics in a clear way or helping readers connect with another person or place from the comfort of their couch. Abby attended Oral Roberts University in Tulsa, Oklahoma, where she earned a degree in writing with concentrations in journalism and business.
