Research Scientist
Senior principal scientist job in Fremont, CA
We're representing a cutting-edge AI organization building autonomous systems that can
reason, plan, and interact with the physical world.
This is a chance to join a small, elite research team pushing the frontier of LLM-driven autonomy.
⭐ The Opportunity
You'll lead research that powers intelligent agents capable of long-horizon reasoning, structured tool-use, and real-world decision-making. This is deep ML research with immediate, tangible impact.
What You'll Work On
Building LLM reasoning and planning frameworks
Designing structured tool-use, memory, reflection, and multi-step workflows
Developing safe, robust policies for autonomous systems
Training and evaluating models across real engineering and scientific tasks
Collaborating with systems, simulation, and infrastructure experts
What We're Looking For
Strong research background in LLMs, reasoning, or agents
Experience with SFT, RLHF/DPO, verifier-guided RL, or related training techniques
Ability to design and evaluate long-horizon behaviors
Comfort working in a fast, interdisciplinary R&D environment
Why Join
Build models that control real physical-world systems, NOT just simulations
Massive scope for autonomy, creativity, and impact
Competitive compensation + meaningful ownership
Research Scientist - Data
Senior principal scientist job in Fremont, CA
⚡ Research Scientist - Data focus
💊 Foundation Models, AI Research Institute
🌎 San Francisco Bay Area, USA
💸 $200,000 - $350,000 salary + bonus
Come join a revolutionary AI research lab in SF Bay Area that is poised to develop & publish high-impact breakthroughs in GenAI - across LLMs and Multimodal AI.
As part of the team, you'll work at the intersection of data, large-scale training, and foundation model innovation. You will collaborate with world-class researchers, data scientists, and engineers to solve critical challenges in creating robust, scalable, and reasoning-capable LLMs. Your research will shape the way data is curated, processed, and leveraged to train the next generation of intelligent systems.
Responsibilities:
Lead research on data-centric approaches for LLMs, including pretraining corpus design, data valuation, and speculative decoding strategies.
Develop pipelines to process challenging data sources into structured and reproducible training datasets.
Build and optimize agentic data pipelines, integrating retrieval, self-curation, and multi-agent feedback for high-quality training and evaluation data.
Collaborate with researchers on alignment and reasoning-focused training that leverage data-driven approaches for improving LLM capabilities.
Prototype and deploy evaluation frameworks to measure data quality, coverage, and downstream impact on LLM reasoning.
Publish findings at top-tier venues (e.g., NeurIPS, ICLR, ACL, EMNLP) and represent the institute at international conferences.
Contribute to open-source tools, datasets, and benchmarks that advance the global foundation model research community.
Requirements:
Master's degree in Computer Science, Data Science, or a related technical field (PhD strongly preferred)
Experience collecting and curating high-quality text data including multi-lingual data.
Hands-on experience with large-scale dataset curation and preprocessing for ML/LLM training.
Prior works synthesizing complex datasets. Code, math, and agentic data are higher priority
Experience with ML infrastructure for scalable training, evaluation, and debugging.
Experience at the intersection of data and post-training (RL/SFT)
Proven ability to independently drive research questions related to data quality, scaling, or reasoning.
Preferred Experience:
Experience with retrieval-augmented generation (RAG), agentic data pipelines, or reasoning benchmarks.
Contributions to speculative decoding, self-curation, or reinforcement learning from synthetic data.
Background in knowledge graphs, semantic search, or indexing systems.
Strong publication record in leading AI conferences.
Prior contributions to open-source ML data tools or benchmarks.
Prior work on speculative decoding/contributions to LLM serving engines
Prior work on training LLM-as-a-judge
Deep expertise with tokenization/training tokenizers
Why apply:
Opportunity to build out a new division at the forefront of AI innovation
FAANG competitive salary & package
Work alongside superstars from FAANG labs & leading AI companies
Medical, Dental and Vision Insurance
Relocation package available
🌎 San Francisco Bay Area, USA
📧 Interested in applying? Please click on the ‘Easy Apply' button or alternatively email me your resume at
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Founding ML Scientist
Senior principal scientist job in Fremont, CA
Stage: Seed
Team Size: < 10
We're looking for an Applied RS who can run the gamut of ML from infra to modeling and own the entire ML pipeline--taking advanced models into production. Our ideal candidate will be looking to build a co-pilot product from the ground up: helping to drive everything from key architectural decisions, applying SOTA methods, and shipping advanced production models in close collaboration with the founders. In key role, you will have real product ownership and the chance to influence not just what gets built, but how it gets built in a true 0->1 scenario.
If you have 5+ years of experience in Machine Learning (infra and modeling) with 1+ years post-training LLM's and are thinking about starting your own company someday, this could be a great entry-way for you. Not only would you get real-world experience with something so early, but you'd get a chance to make a name for yourself with our investment team as well (making it much easier to get a chance to pitch us on your own idea in the future).
About Greylock
Greylock is a 1st-tier, early-stage venture capital firm that partners with exceptional founders at the seed and Series A stages. Our mission is to help realize rare potential - backing category-defining companies such as Figma, Anthropic, Ramp, Abnormal Security, Rubrik, Airbnb, LinkedIn, Roblox, Dropbox, and Coinbase.
About the Greylock Recruiting Team
As full-time, salaried employees of Greylock, our team provides free candidate referrals and introductions to our active portfolio companies. Combined, we bring over 125 years of in-house recruiting experience across startups and large-scale tech companies
Senior Scientist or Associate Principal Scientist, LBA Platforms
Senior principal scientist job in Pleasanton, CA
Crystal Bio Solutions is a CRO providing global-standard services in GLP/GCLP bioanalysis and biomarker. Our clients include multinational pharmaceutical companies and biotech companies. The Bioanalysis & Biomarkers Department specializes in Method Development, Method Validation, GLP/GCLP Bioanalysis for PK, immunogenicity and biomarkers. The team has successfully supported non-GLP, GLP (non-clinical) and GCLP (clinical) projects. The role is responsible for providing bioanalytical support for both pre-clinical and clinical projects and partnering with our clients for project success.
Key Responsibilities
* Independently propose assay design and/or strategy, develop, validate, conduct, and troubleshoot bioanalytical methods, including PK, ADA (Immunogenicity) and Biomarker, for GLP/GCLP sample testing and data reporting. Present and interpret data internally and/or externally as needed.
* Serve as the Principal Investigator responsible for interaction with the client from the study design to scheduling, conducting, reporting, and transferring data. Ensure responsiveness to the client, timely delivery, and overall customer satisfaction.
* Serve as Subject Matter Expert (SME) for LBA (ELISA multimode reader & Meso-Scale Discovery (ECL)).
* Author and/or review key regulatory documents, validation plans and reports, laboratory data, and technical reports.
* Provide oversight of the laboratory, mentor junior staff, and collaborate to keep improving operational excellence.
* Assist in establishing and improving policies, procedures, work instructions and SOPs.
* Understand and adhere to corporate standards regarding code of conduct, Environment Health & Safety (EHS), and GLP/GCP/GDP compliance.
* Perform other related duties as assigned.
Qualifications & Educational Requirements
* Ph.D., M.Sc., M.A., B.A., in Biology, Immunology, Chemistry, Pharmacology, or other related scientific fields required, including a minimum of 4+(Ph.D.), 9+(Master's) or 12+(Bachelor's) years of Pharma/Biotech/CRO experience.
* Hands-on experience and strong knowledge of GLP/GCLP bioanalysis.
* Experience in LBA-based Method Development, Validation for PK, ADA (Immunogenicity) and PD Biomarker assays.
* An extensive knowledge of Immunogenicity Method Development, Validation and Sample Analysis is highly desirable.
* Experience with Watson LIMS and in CRO environment is preferred.
* Supervisory experience in both project and talent (people) management is preferred.
* Ability to work independently and pay good attention to details.
* Ability to achieve objectives/timelines through collaborative efforts with co-workers, managers, and clients.
* Must be goal-oriented, compliance-ensured, quality-conscientious, and client-focused.
* Effective writing and communication skills.
How to Apply
CV can be e-mailed directly to: career_************************. Be sure to denote the Job Title of the position you are applying.
Easy ApplySr Formulations Scientist III - Valent U.S.A LLC
Senior principal scientist job in San Ramon, CA
Job Description
About us:
Valent U.S.A. LLC, a wholly owned subsidiary of Sumitomo Chemical Company, Limited, engages in the development, registration, sales, and marketing of integrated technological solutions for crop production and pest management that deliver value for our customers and stakeholders. A leading crop protection firm serving the agricultural and non-crop products markets in North America, Valent products help growers produce safe and abundant food and fiber crops, and horticultural professionals improve the quality of life for their customers. The corporate motto, Products That Work, From People Who Care , describes the company's business philosophy. Valent seeks out and provides customers with innovative and effective solutions to their production challenges. Our vision is to be the best company delivering integrated solutions of biorational and traditional crop protection solutions to our customers. Valent is dedicated to creating a world that is healthier and more comfortable, and that has a sustainable abundance of quality, affordable food, helping crops to be the ultimate renewable resource.
General Description:
The purpose of this position is to conduct research and development efforts for Herbicide product development from conceptual phase through commercial production by working in coordination with the Senior Manager of Formulation Development and Analytical. The position is responsible to execute all related scientific research and/or development studies assigned for critical product development by individual effort or in collaboration with staff. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plan and executes lab research. Maintain broad knowledge of state-of-the-art principles and theories. Make major contributions to scientific literature and conferences. Serve as in-house and outside consultant. May act as spokesperson on corporate research and development and advise top management. Participate in development of patent applications. Participate in promoting the professional development of junior research staff. Interfaces with various associated departments. Uses professional concepts to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways.
Principal Responsibilities:
Use expert knowledge to independently plan, execute, and/or direct complex research and development projects for new or improved/innovative formulations and formulation technology, particularly in herbicide product segment. Manage formulation development activities through all stages of the project: development of preliminary formulations for efficacy testing, formulation optimization and processing studies to establish formulation for regulatory studies and EPA registration, scale-up, and commercial production. Exercise wide latitude in determining objectives and approaches, selecting methods, techniques and evaluation criteria for obtaining results. Requires coordination and communication with other Valent teams, including, Product Development Managers, Regulatory Project Managers, Toxicology Manager, Supply Chain, and production facility personnel. Provide technical support services to Manufacturing, Product Development Managers, Marketing, and Sales to solve technical problems or customer complaints related to Valent formulations.
Work directly and independently with Market/Product Managers, Technology Managers and Product Development specialists to investigate feasibility for exploratory projects and to set objectives and maintain timelines for development projects for new or improved/innovative formulations and formulation technology. Serve as a resource and source for ideas for product innovation. Interact with Sumitomo Group Companies' formulation chemists, consultants, and industry personnel regarding research, development, and alternative technologies for formulation improvements. Evaluate formulation technology advances for application to Valent products and lead implementation efforts across product line. Viewed as an expert in all aspects of formulation research and development.
Communicate proactively and effectively, both orally and in writing, with Senior Formulation Manager, Technology staff, personnel in other functional areas, and with appropriate external personnel, to ensure that projects are progressing on track and meet objectives and timelines: provide information on formulation project status and results; set priorities; resolve problems or issues; coordinate activities; and obtain feedback and needed information or assistance. Serve as consultant to management and as an external spokesperson for the company. Advise on direction for strategic planning from technical perspective to meet company objectives. May serve on industry committees or task forces.
Engage Associate/Formulations Scientists in conduct of tasks/projects; train and develop; communicate priorities and objectives when collaborating; review work from subordinates. Serve as a resource/trainer/mentor for junior members of the group. Follow safety and regulatory plans, and waste disposal procedures. Participate in all required safety meetings and training programs.
Perform research and/or development in collaboration with others for projects. Make detailed observations, analyze data and interpret results. Exercise technical discretion in the design, execution and interpretation of experiments that contribute to project strategies. Prepare technical reports, summaries, protocols, and quantitative analyses. Maintain familiarity with current scientific literature. Contribute to project process within his/her scientific discipline. Investigate, create and develop new methods and technologies for project advancement. Maintain high level of professional expertise through familiarity with scientific literature. May participate in scientific conferences and contribute to scientific journals. May be responsible for identifying patentable inventions. Use professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.
Manage all formulation development activities for assigned products. This includes constant interfacing with the other members of the Seed Treatment, Fungicide, Insecticide and Herbicide Teams in both Field Development and Marketing. Maintain expertise in all aspects of technology including requirements for various formulations, application methods, and test methods. Utilize knowledge and expertise to develop formulations that can be registered, commercialized, and meet customer needs and expectations. Serve as formulation technology expert in meetings with various companies, customers, and prospective or established business partners.
Qualifications:
MS, PhD, JD or equivalent, with 8+ years of related experience.
Chemistry, related science degree.
Experience in spreadsheets and word processing, problem solving, communication, detail oriented, evaluation and interpretation of data, instrument/equipment operation, maintenance and repair.
In-depth knowledge of chemistry lab procedures, formulation development, manufacturing and packaging of agricultural chemicals and EPA approved inerts. Techniques for preparation and evaluation of formulations.
More than 8 years of experience in preparation and evaluation of agricultural chemical formulations. More than 6 years experience in managing laboratory formulation research projects and technical support in the agricultural chemical industry.
Demonstrated creativity, championing skills and deep technical knowledge of herbicide formulations and performance/stability requirements.
Physical Demands and Work Environment (LAB Position)
The physical demands and work environment characteristics described below are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Physical Demands include constant sitting, walking, standing, bending at the neck and waist, squatting, climbing, kneeling, crawling, twisting at the neck and waist, simple grasping, power grasping, and fine manipulation with hands, pushing and pulling with hands, reaching above shoulder level, and lifting and carrying up to 25 lbs.; and occasional lifting and carrying of up to 50 lbs. Will require the employee to lift and carry up to a 2.5-gallon jug containing liquid formulations and products. May be required to work in powder room environment to test or develop dry formulation products. This includes milling activities for solid formulations (granular and powder) in a dusty environment that will require the use of respirator and other personal protective equipment.
Work Environment includes exposure to or working in or around moving cars, trucks, forklifts, equipment and machinery including a computer keyboard and mouse; uneven ground; excessive noise; extremes in temperature, humidity, or wetness; dust, gas, fumes, or chemicals; heights; operation of foot controls or repetitive foot movement. May be required to wear a respirator and other personnel protective equipment (including special visual or auditory equipment).
May require occasional travel.
Requires on-site laboratory base of operation.
Frequency Definitions: Constant = Over 40% / Frequent = Up to 40% / Occasional = Up to 10%
What We Offer
We recognize that compensation and benefits play a crucial role in your career decisions. That's why we're dedicated to equitable pay practices and transparency in how we reward our employees.
Base Salary: The estimated annual base salary for this position ranges from:
$100,000 to $145,000 . Individual pay is based upon location, skills, experience, and other relevant factors.
Incentives: All full-time employees are eligible for an incentive program or profit-sharing program in addition to their base salary.
Benefits:
High-quality healthcare coverage starting on day one, with options for medical (HSA/HRA), vision, and dental plans
5% company contribution to your 401(k), plus a quarterly discretionary bonus
Immediate 100% vesting of all retirement contributions
Financial assistance programs to support your goals
Life and disability insurance for added security
Generous paid time off, including vacation, holidays, and volunteer days
Our Commitment to a Sustainable Future
At Valent Group of Companies, we're proud to power a sustainable future through our work. Sustainability and corporate social responsibility (CSR) have been at the core of our culture since the beginning. Today, they continue to drive everything we do.
Join us in making a meaningful impact and contributing to a better world.
Valent U.S.A., Valent North America LLC, Valent BioSciences LLC and Mycorrhizal Applications LLC are an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation and/or identity, national origin, citizenship, immigration status, disabilities, or protected veteran status.
#LI-ONSITE
Sr Formulations Scientist III - Valent U.S.A LLC
Senior principal scientist job in San Ramon, CA
About us:
Valent U.S.A. LLC, a wholly owned subsidiary of Sumitomo Chemical Company, Limited, engages in the development, registration, sales, and marketing of integrated technological solutions for crop production and pest management that deliver value for our customers and stakeholders. A leading crop protection firm serving the agricultural and non-crop products markets in North America, Valent products help growers produce safe and abundant food and fiber crops, and horticultural professionals improve the quality of life for their customers. The corporate motto, Products That Work, From People Who Care , describes the company's business philosophy. Valent seeks out and provides customers with innovative and effective solutions to their production challenges. Our vision is to be the best company delivering integrated solutions of biorational and traditional crop protection solutions to our customers. Valent is dedicated to creating a world that is healthier and more comfortable, and that has a sustainable abundance of quality, affordable food, helping crops to be the ultimate renewable resource.
General Description:
The purpose of this position is to conduct research and development efforts for Herbicide product development from conceptual phase through commercial production by working in coordination with the Senior Manager of Formulation Development and Analytical. The position is responsible to execute all related scientific research and/or development studies assigned for critical product development by individual effort or in collaboration with staff. Investigates the feasibility of applying a wide variety of scientific principles and concepts to potential inventions, products and problems. Plan and executes lab research. Maintain broad knowledge of state-of-the-art principles and theories. Make major contributions to scientific literature and conferences. Serve as in-house and outside consultant. May act as spokesperson on corporate research and development and advise top management. Participate in development of patent applications. Participate in promoting the professional development of junior research staff. Interfaces with various associated departments. Uses professional concepts to contribute to the development of company concepts and principles to achieve objectives in creative and effective ways.
Principal Responsibilities:
Use expert knowledge to independently plan, execute, and/or direct complex research and development projects for new or improved/innovative formulations and formulation technology, particularly in herbicide product segment. Manage formulation development activities through all stages of the project: development of preliminary formulations for efficacy testing, formulation optimization and processing studies to establish formulation for regulatory studies and EPA registration, scale-up, and commercial production. Exercise wide latitude in determining objectives and approaches, selecting methods, techniques and evaluation criteria for obtaining results. Requires coordination and communication with other Valent teams, including, Product Development Managers, Regulatory Project Managers, Toxicology Manager, Supply Chain, and production facility personnel. Provide technical support services to Manufacturing, Product Development Managers, Marketing, and Sales to solve technical problems or customer complaints related to Valent formulations.
Work directly and independently with Market/Product Managers, Technology Managers and Product Development specialists to investigate feasibility for exploratory projects and to set objectives and maintain timelines for development projects for new or improved/innovative formulations and formulation technology. Serve as a resource and source for ideas for product innovation. Interact with Sumitomo Group Companies' formulation chemists, consultants, and industry personnel regarding research, development, and alternative technologies for formulation improvements. Evaluate formulation technology advances for application to Valent products and lead implementation efforts across product line. Viewed as an expert in all aspects of formulation research and development.
Communicate proactively and effectively, both orally and in writing, with Senior Formulation Manager, Technology staff, personnel in other functional areas, and with appropriate external personnel, to ensure that projects are progressing on track and meet objectives and timelines: provide information on formulation project status and results; set priorities; resolve problems or issues; coordinate activities; and obtain feedback and needed information or assistance. Serve as consultant to management and as an external spokesperson for the company. Advise on direction for strategic planning from technical perspective to meet company objectives. May serve on industry committees or task forces.
Engage Associate/Formulations Scientists in conduct of tasks/projects; train and develop; communicate priorities and objectives when collaborating; review work from subordinates. Serve as a resource/trainer/mentor for junior members of the group. Follow safety and regulatory plans, and waste disposal procedures. Participate in all required safety meetings and training programs.
Perform research and/or development in collaboration with others for projects. Make detailed observations, analyze data and interpret results. Exercise technical discretion in the design, execution and interpretation of experiments that contribute to project strategies. Prepare technical reports, summaries, protocols, and quantitative analyses. Maintain familiarity with current scientific literature. Contribute to project process within his/her scientific discipline. Investigate, create and develop new methods and technologies for project advancement. Maintain high level of professional expertise through familiarity with scientific literature. May participate in scientific conferences and contribute to scientific journals. May be responsible for identifying patentable inventions. Use professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.
Manage all formulation development activities for assigned products. This includes constant interfacing with the other members of the Seed Treatment, Fungicide, Insecticide and Herbicide Teams in both Field Development and Marketing. Maintain expertise in all aspects of technology including requirements for various formulations, application methods, and test methods. Utilize knowledge and expertise to develop formulations that can be registered, commercialized, and meet customer needs and expectations. Serve as formulation technology expert in meetings with various companies, customers, and prospective or established business partners.
Qualifications:
MS, PhD, JD or equivalent, with 8+ years of related experience.
Chemistry, related science degree.
Experience in spreadsheets and word processing, problem solving, communication, detail oriented, evaluation and interpretation of data, instrument/equipment operation, maintenance and repair.
In-depth knowledge of chemistry lab procedures, formulation development, manufacturing and packaging of agricultural chemicals and EPA approved inerts. Techniques for preparation and evaluation of formulations.
More than 8 years of experience in preparation and evaluation of agricultural chemical formulations. More than 6 years experience in managing laboratory formulation research projects and technical support in the agricultural chemical industry.
Demonstrated creativity, championing skills and deep technical knowledge of herbicide formulations and performance/stability requirements.
Physical Demands and Work Environment (LAB Position)
The physical demands and work environment characteristics described below are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Physical Demands include constant sitting, walking, standing, bending at the neck and waist, squatting, climbing, kneeling, crawling, twisting at the neck and waist, simple grasping, power grasping, and fine manipulation with hands, pushing and pulling with hands, reaching above shoulder level, and lifting and carrying up to 25 lbs.; and occasional lifting and carrying of up to 50 lbs. Will require the employee to lift and carry up to a 2.5-gallon jug containing liquid formulations and products. May be required to work in powder room environment to test or develop dry formulation products. This includes milling activities for solid formulations (granular and powder) in a dusty environment that will require the use of respirator and other personal protective equipment.
Work Environment includes exposure to or working in or around moving cars, trucks, forklifts, equipment and machinery including a computer keyboard and mouse; uneven ground; excessive noise; extremes in temperature, humidity, or wetness; dust, gas, fumes, or chemicals; heights; operation of foot controls or repetitive foot movement. May be required to wear a respirator and other personnel protective equipment (including special visual or auditory equipment).
May require occasional travel.
Requires on-site laboratory base of operation.
Frequency Definitions: Constant = Over 40% / Frequent = Up to 40% / Occasional = Up to 10%
What We Offer
We recognize that compensation and benefits play a crucial role in your career decisions. That's why we're dedicated to equitable pay practices and transparency in how we reward our employees.
Base Salary: The estimated annual base salary for this position ranges from:
$100,000 to $145,000 . Individual pay is based upon location, skills, experience, and other relevant factors.
Incentives: All full-time employees are eligible for an incentive program or profit-sharing program in addition to their base salary.
Benefits:
High-quality healthcare coverage starting on day one, with options for medical (HSA/HRA), vision, and dental plans
5% company contribution to your 401(k), plus a quarterly discretionary bonus
Immediate 100% vesting of all retirement contributions
Financial assistance programs to support your goals
Life and disability insurance for added security
Generous paid time off, including vacation, holidays, and volunteer days
Our Commitment to a Sustainable Future
At Valent Group of Companies, we're proud to power a sustainable future through our work. Sustainability and corporate social responsibility (CSR) have been at the core of our culture since the beginning. Today, they continue to drive everything we do.
Join us in making a meaningful impact and contributing to a better world.
Valent U.S.A., Valent North America LLC, Valent BioSciences LLC and Mycorrhizal Applications LLC are an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation and/or identity, national origin, citizenship, immigration status, disabilities, or protected veteran status.
#LI-ONSITE
Auto-ApplyScientist
Senior principal scientist job in Hayward, CA
Job Description
Title: Scientist
Reports To: Group Leader
Company
Frontage Laboratories Inc. is an award winning, publicly listed, full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada, and China, growing significant growth. Our core competencies include pre-clinical, drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
Position/Job Summary
We are seeking a highly motivated and experienced Scientist specializing in LC-MS/MS to join our dynamic team. This individual will play a pivotal role in quantitative bioanalysis and the characterization and identification of drug metabolites, contributing to our understanding of DMPK (Drug Metabolism and Pharmacokinetics) and its impact on drug safety and efficacy.
Roles & Responsibilities
Develop and optimize sample preparation and analytical methodology for quantitative measurement of drugs in a variety of modalities and metabolite profiling/identification using state-of-the-art LC-MS/MS and high-resolution mass spectrometry (HRMS).
Lead and execute LC-MS/MS-based projects in a timely and high-quality manner.Interact with clients to provide actionable insights on method development and sample analysis-related challenges.
Operate, maintain, and troubleshooting LC-MS/MS instruments; serve as instrument lead as needed.
Prepare and review scientific reports, presentations, and regulatory documents to ensure accuracy and compliance with industry standards.
Stay updated on advancements in LC-MS/MS technologies and methodologies.
Collaborate with cross-functional teams and provide technical guidance when needed.
Mentor and train junior lab staff.
Education, Experience & Skills Required
Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
Solid hands-on experience with LC-MS/MS-based bioanalytical method development including sample preparation, instrument operation and data processing.
Proven track record operating LC-MS/MS systems in a bioanalytical lab
Strong expertise in drug metabolism and biotransformation, with hands-on experience in metabolite identification using LC-MS/MS and HRMS.
Demonstrated ability to analyze and interpret complex mass spectrometry data and provide detailed reports.
Excellent communication skills and ability to work both independently and collaboratively in a cross-functional team environment.
Experience in pharma or biotech environment is a plus
Salary and Benefits:
Frontage Laboratories offers a competitive compensation and generous benefits package including health and dental insurance, a 401(k) plan, health insurance, short and long-term disability insurance, life insurance etc
Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.
Scientist
Senior principal scientist job in Pleasanton, CA
Our client's Pathology Biology & Integrated Analytics group is seeking a highly motivated Scientist for molecular cloning, cell culture, FPLC purification and antibody engineering and characterization. The qualified candidate will join a team of scientists focused on monoclonal antibody development for IVD and CDx assay. This position will be actively participating in antibody development, engineering, production and characterization. Job function requires the ability to evaluate, summarize and report study results, make independent decision and collaborate with teams at multiple sites.
Responsibilities:
Plans and/or manages smaller, less complex local projects (e.g. with moderate project management complexity, problem definition, and/or short to medium term implications).
Participates in project teams across the R&D department and functional groups
Can represent the Team Lead in project teams in his/her absence on instruction
Ensures that quality standards are met and plans and coordinates the performance of tasks largely independently.
Is aware of new developments in the field and refers to the possible use of these in diagnostics.
Contributes to collaboration and close networking within the departments as part of R&D projects.
Analyzes and interprets the R&D results largely independently and presents them to the relevant committees within their own function.
Uses specified strategies to resolve problems and acts within defined guidelines.
Scientist
Senior principal scientist job in Pleasanton, CA
Our client, a world leader in diagnostics and life sciences, is looking for a "Scientist” based out of Pleasanton, CA.
Job Duration: Long Term Contract (Possibility Of Further Extension)
Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K
Job Description:
This position plays a key role in the development of molecular diagnostic tests for the Point -of -Care market. The ideal candidate will have hands -on experience in developing and optimizing molecular assays, including reagent formulation, test design, and method validation. Proficiency in PCR assay data analysis, use of standard development tools, and familiarity with process capability analysis and IT systems are highly desirable.
Responsibilities:
Design, conduct, and monitor laboratory experiments following established procedures and quality standards (ISO, QSR, OSHA).
Analyze and interpret experimental data using quantitative and software -based methods; prepare and present technical reports.
Maintain accurate and timely documentation in electronic lab notebooks.
Support routine lab operations, safety compliance, and instrument troubleshooting.
Collaborate with cross -functional teams and communicate project progress and findings.
Work independently to plan, execute, and optimize experiments, offering solutions to technical challenges.
Qualifications:
Bachelor's degree in Biological/Life Sciences, Chemistry, Biochemistry, or a related field (or equivalent combination of education and experience).
0-1 year of related laboratory experience in molecular diagnostics, assay development, or related field.
Strong analytical, documentation, and communication skills.
Experience with PCR, reagent optimization, and data analysis tools preferred.
If interested, please send us your updated resume at
**********************/***************************
Easy ApplyScientist, Preclinical - Sacramento CA
Senior principal scientist job in Sacramento, CA
The Jackson Laboratory in Sacramento, CA has an excellent opportunity for a Scientist to join the Preclinical team! The Scientist may be responsible for designing, executing, and overseeing scientific research projects, applying advanced methodologies and techniques to explore and expand knowledge within a specific discipline. They lead experiments, analyze data, and interpret results while collaborating with interdisciplinary teams to achieve research goals.
Key Responsibilities
* May Design, plan, and execute experiments, applying advanced scientific principles and methodologies within the field.
* Analyze and may interpret experimental data using statistical tools and software, drawing meaningful conclusions and identifying trends.
* May prepare research findings for publication in scientific journals, present at conferences, and communicate discoveries to peers and stakeholders.
* Lead research initiatives, setting objectives, timelines, and strategies to achieve project goals.
* Collaborate with cross-functional teams, providing guidance and mentorship to junior researchers, fostering a collaborative research environment.
* Contribute to grant proposals, securing funding for research projects, and managing budgets effectively.
Minimum Qualifications
* Master's Degree in oncology, immunology, animal pharmacology, or a relevant field required. Ph.D. preferred.
* Four or more years of relevant experience in a contract research laboratory, pharmaceutical industry, 6 years preferred
* May have a proven track record of conducting high-quality scientific research, evidenced by publications in reputable journals and successful project leadership.
* Proficiency in specific methodologies, tools, and instrumentation pertinent to the research area.
* Strong leadership, project management, and mentorship abilities to guide and inspire a team of researchers.
* Excellent written and verbal communication skills for presenting findings, collaborating with peers, and writing grant proposals.
* May have ability to innovate, propose novel approaches, and solve complex scientific problems.
* Flexibility to adapt to changing research needs and technologies.
* Strong networking skills to establish collaborations and partnerships within the scientific community.
* Ability to develop long-term research strategies aligned with organizational goals.
The salary range is $99,284-$129,069. Salary will be determined based on qualifications and experience.
#CA-AM11
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit ************
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Auto-ApplySenior Scientist - Formulation Development (R&D)
Senior principal scientist job in Sacramento, CA
About the Company:
Nivagen is a global company dedicated to enhancing lives by developing and providing cost-effective generic prescription drugs and over-the-counter products for the North American market. For over a decade, we've remained steadfast in our commitment to core values of excellence, integrity, and respect for people. Our team of professionals collaborates tirelessly to pioneer advancements in manufacturing, distribution, and quality control, ensuring a holistic approach to healthcare. Through vertical integration of the pharmaceutical supply chain, cutting-edge technology, and unwavering dedication to excellence, we continually strive to redefine medication accessibility and affordability. We prioritize our employees' well-being by offering competitive pay, comprehensive benefits, and robust training and development opportunities. By investing in our workforce and fostering a culture of growth and support, we empower our team to drive innovation and make a positive impact in the healthcare industry. At Nivagen, our mission is clear: to make a meaningful difference in people's lives by delivering high-quality, affordable medications while upholding the highest standards of integrity and excellence.
Job Type:
Full Time
Job Location:
Nivagen Pharmaceuticals Inc., Sacramento, CA
About the Job:
Title of the Position: Senior Scientist - Formulation Development
We are seeking a highly skilled and experienced Senior Scientist to join our Formulation Development team. The successful candidate will play a critical role in the development and optimization of drug formulations from early-stage research through commercialization. This position requires a deep understanding of formulation principles, a strong scientific background, and a proven track record of success in the pharmaceutical industry.
Responsibilities:
Lead the design, development, and optimization of complex injectable and sterile dosage forms.
Develop and implement robust formulation development strategies aligned with regulatory guidelines (e.g., Quality by Design, FDA).
Apply scientific fundamentals and creative problem-solving skills to solve complex technical issues
Conduct rigorous experimental design studies (e.g., factorial design) to achieve project objectives.
Collaborate closely with cross-functional teams, including Technical Services, Operations, and Regulatory Affairs.
Define scope, timeline, and resource needs of functional activities and keep team on schedule
Participate in evaluation of new product opportunities.
Ensure timely and high-quality documentation for regulatory submissions.
Stay updated with all FDA and regulatory requirements/guidelines.
Provide mentorship and leadership to team members.
Stay up to date with the latest scientific advancements in formulation development and applying new technologies to improve product performance.
Author and review technical reports, protocols, and regulatory documents.
Additional duties and assignments as needed.
Qualifications:
Education/Experience:
Ph.D. or Postgraduate degree in Pharmacy, Pharmaceutical Sciences, Chemistry, or a related field.
3+ years of hands-on experience in sterile/Injectable pharmaceutical formulation development. (Strong candidates with combinations of education and experience will be considered.)
Strong understanding of formulation principles, excipients, and drug delivery systems.
Hands-on experience with various formulation techniques and equipment.
Proven track record of successful formulation development and commercialization.
Experience with statistical design of experiments (DOE) and data analysis.
Knowledge, Skills, and Abilities:
Proven track record of successful formulation development for various sterile dosage forms.
Strong leadership, project management, and organizational skills.
Expertise in complex injectable and sterile dosage form development.
Demonstrated ability to conduct independent research and problem-solving.
Requirements:
Must live in or be willing to move to the Sacramento Metropolitan Region (approximately 40 miles in radius).
Benefits:
Pay range $70,000-$90,000 per Year
Yearly bonus eligibility
Benefits: Nivagen offers a wide variety of benefits and programs to support health and well-being
Medical, dental and vision coverage
Paid time off plan
401k savings plan
Additional Information:
Nivagen to afford equal opportunity for employment to all individuals regardless of race, color, age, national origin, physical or mental disability, history of disability, ancestry, citizenship status, political affiliation, religion, gender, transgender, gender identity, marital status, status as a parent, sexual orientation, veteran status, genetic information or other factors prohibited by law, and to prohibit harassment or retaliation based on any of these factors.
Auto-ApplyScientist - Bioanalysis & Biomarkers- LCMS
Senior principal scientist job in Pleasanton, CA
Purpose
Amador Bioscience (AmadorBio) is a Translational & Clinical Pharmacology CRO providing global-standard services in quantitative clinical pharmacology, GLP/GCLP bioanalysis, clinical research, and regulatory filing to leading biopharmaceutical companies. Our clients include multinational pharmaceuticals and mid- and small-size biotech companies.
Amador Laboratory Services Division specializes in bioanalysis (PK/PD/ADA), biomarkers, assay development & validation, and sample analysis. The team has successfully supported multiple non-GLP, GLP (nonclinical) and GCLP (clinical) projects. To meet the needs of business growth, we are looking for a highly motivated, experienced scientist/senior scientist to join our passionate team to partner with our clients for success. The successful candidate will be responsible for providing bioanalytical supports for both pre-clinical and clinical projects and will report to the Laboratory Head.
Role and Responsibilities
Develop, validate, conduct, and troubleshoot UHPLC and LC-MS analytical methods to quantitate large molecules and metabolites in biological fluids
Present/interpret data internally and/or externally as needed.
Participate in interactions with clients and ensure overall customer satisfaction.
Interacts with QA to ensure all audit findings are addressed in a timely fashion.
Author and/or review key regulatory documents, laboratory data, and technical reports.
Assist with the oversight of the laboratory and mentor junior staff.
Assist in establishing and improving all policies, procedures and required SOP documentation.
Understand and adhere to corporate standards regarding code of conduct, safety, and GLP/GCP/GDP compliance.
Ensure and reviews lab maintenance activities and maintains a clean and safe lab environment
Develop, write, and review protocols and SOPs.
Participate in regulatory compliance activities
Perform all other related duties as assigned
Qualifications and Education Requirements
Ph.D., Master's, or Bachelor's degree in biology, immunology, chemistry, pharmacology, or other related scientific fields required.
Requires a minimum 0-9 years of relevant experience in a CRO or drug-development environment.
Ability to work independently and have good attention to details.
Good knowledge of regulated bioanalysis. GLP/GCLP experience preferred.
Ability to achieve objectives/timelines through collaborative efforts with coworkers, managers, and clients.
Must be goal-oriented, quality-conscientious, and client-focused.
Effective written and verbal communication skills.
Experienced with LCMS or tandem Mass-Spec method development and validation for PK and/or biomarker analysis.
Preferred Skills
Proficient in MS Office
Watson LIMS
Strong knowledge of GLP/GCLP regulations
Salary range is from $105,000 to 120,000
Auto-ApplySenior Bioinformatics Scientist
Senior principal scientist job in Pleasanton, CA
PromptBio, established in 2023 in Pleasanton, California, is a biotechnology company dedicated to developing AI-driven workflows that automate the discovery of novel biomarkers from multi-omics data, translating them into clinical diagnostic applications.
Job Description
We seek a motivated Senior Bioinformatics Scientist to join our interdisciplinary team, focusing on integrating AI solutions within the life sciences domain. The role will have significant customer facing responsibilities.
Key Responsibilities
Work closely with the Business Development team and serve as the primary scientific point of contact for enterprise customers, building deep technical relationships and helping customers derive biological insights.
Design and implement custom multi-omics analysis workflows (genomics, transcriptomics, proteomics, metabolomics, epigenomics) tailored to customer use cases
Evaluate and incorporate new bioinformatics tools, algorithms, and computational methods to stay at the forefront of the field.
Author and contribute to scientific publications, presentations, and IP filings.
Qualifications
Minimum of 3 years of industry experience in processing and analyzing mutli-omics datasets (e.g., genomics, transcriptomics, proteomics, metabolomics, epigenomics) and deriving meaningful insights
Hands-on experience with applying advanced statistical methods and machine learning techniques to analyze omics data and identify novel biomarkers, therapeutic targets, and molecular mechanisms.
Excellent publication record and communication skills with ability to explain concepts to diverse audiences.
Fluency in programming languages like Python, R, and bioinformatics workflows (e.g., using Nextflow, Snakemake, or similar).
Familiarity with software engineering best practices, including testing, code reviews, version control (e.g., Git), and containerization.
Experience with cloud computing environments and AI technologies is a significant plus.
PhD in Bioinformatics, Computational Biology, Genomics, or related field
Desired Attributes
Entrepreneurial mindset with comfort in ambiguous, fast-paced environments.
Proactive, results-oriented, and driven with a "get things done" mindset.
Strong problem-solving skills and adaptability to evolving project requirements.
Intellectual curiosity about emerging AI technologies and their biological applications.
Collaborative team player who thrives in dynamic environments.
Additional Information
Financial security through competitive compensation, incentives, and retirement plan
Healthcare and well-being programs including competitive medical, dental, and vision benefits
Generous paid time-off including vacation, sick time, holidays, and discretionary winter shutdown
401(k) retirement savings with a generous company match
Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more
We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs
Hybrid work opportunities.
Senior Bioinformatics Scientist
Senior principal scientist job in Pleasanton, CA
PromptBio, established in 2023 in Pleasanton, California, is a biotechnology company dedicated to developing AI-driven workflows that automate the discovery of novel biomarkers from multi-omics data, translating them into clinical diagnostic applications.
Job Description
We seek a motivated Senior Bioinformatics Scientist to join our interdisciplinary team, focusing on integrating AI solutions within the life sciences domain. The role will have significant customer facing responsibilities.
Key Responsibilities
Work closely with the Business Development team and serve as the primary scientific point of contact for enterprise customers, building deep technical relationships and helping customers derive biological insights.
Design and implement custom multi-omics analysis workflows (genomics, transcriptomics, proteomics, metabolomics, epigenomics) tailored to customer use cases
Evaluate and incorporate new bioinformatics tools, algorithms, and computational methods to stay at the forefront of the field.
Author and contribute to scientific publications, presentations, and IP filings.
Qualifications
Minimum of 3 years of industry experience in processing and analyzing mutli-omics datasets (e.g., genomics, transcriptomics, proteomics, metabolomics, epigenomics) and deriving meaningful insights
Hands-on experience with applying advanced statistical methods and machine learning techniques to analyze omics data and identify novel biomarkers, therapeutic targets, and molecular mechanisms.
Excellent publication record and communication skills with ability to explain concepts to diverse audiences.
Fluency in programming languages like Python, R, and bioinformatics workflows (e.g., using Nextflow, Snakemake, or similar).
Familiarity with software engineering best practices, including testing, code reviews, version control (e.g., Git), and containerization.
Experience with cloud computing environments and AI technologies is a significant plus.
PhD in Bioinformatics, Computational Biology, Genomics, or related field
Desired Attributes
Entrepreneurial mindset with comfort in ambiguous, fast-paced environments.
Proactive, results-oriented, and driven with a "get things done" mindset.
Strong problem-solving skills and adaptability to evolving project requirements.
Intellectual curiosity about emerging AI technologies and their biological applications.
Collaborative team player who thrives in dynamic environments.
Additional Information
Financial security through competitive compensation, incentives, and retirement plan
Healthcare and well-being programs including competitive medical, dental, and vision benefits
Generous paid time-off including vacation, sick time, holidays, and discretionary winter shutdown
401(k) retirement savings with a generous company match
Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more
We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs
Hybrid work opportunities.
Senior Bioinformatics Scientist
Senior principal scientist job in Pleasanton, CA
PromptBio, established in 2023 in Pleasanton, California, is a biotechnology company dedicated to developing AI-driven workflows that automate the discovery of novel biomarkers from multi-omics data, translating them into clinical diagnostic applications.
Job Description
We seek a motivated Senior Bioinformatics Scientist to join our interdisciplinary team, focusing on integrating AI solutions within the life sciences domain. The role will have significant customer facing responsibilities.
Key Responsibilities
Work closely with the Business Development team and serve as the primary scientific point of contact for enterprise customers, building deep technical relationships and helping customers derive biological insights.
Design and implement custom multi-omics analysis workflows (genomics, transcriptomics, proteomics, metabolomics, epigenomics) tailored to customer use cases
Evaluate and incorporate new bioinformatics tools, algorithms, and computational methods to stay at the forefront of the field.
Author and contribute to scientific publications, presentations, and IP filings.
Qualifications
Minimum of 3 years of industry experience in processing and analyzing mutli-omics datasets (e.g., genomics, transcriptomics, proteomics, metabolomics, epigenomics) and deriving meaningful insights
Hands-on experience with applying advanced statistical methods and machine learning techniques to analyze omics data and identify novel biomarkers, therapeutic targets, and molecular mechanisms.
Excellent publication record and communication skills with ability to explain concepts to diverse audiences.
Fluency in programming languages like Python, R, and bioinformatics workflows (e.g., using Nextflow, Snakemake, or similar).
Familiarity with software engineering best practices, including testing, code reviews, version control (e.g., Git), and containerization.
Experience with cloud computing environments and AI technologies is a significant plus.
PhD in Bioinformatics, Computational Biology, Genomics, or related field
Desired Attributes
Entrepreneurial mindset with comfort in ambiguous, fast-paced environments.
Proactive, results-oriented, and driven with a "get things done" mindset.
Strong problem-solving skills and adaptability to evolving project requirements.
Intellectual curiosity about emerging AI technologies and their biological applications.
Collaborative team player who thrives in dynamic environments.
Additional Information
Financial security through competitive compensation, incentives, and retirement plan
Healthcare and well-being programs including competitive medical, dental, and vision benefits
Generous paid time-off including vacation, sick time, holidays, and discretionary winter shutdown
401(k) retirement savings with a generous company match
Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more
We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs
Hybrid work opportunities.
Scientist - TS/MS Parenteral
Senior principal scientist job in Concord, CA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Responsibilities:
The Scientist - TSMS PAR will initially focus on the delivery of parenteral operations, specifically regarding technical transfer and process validation. TSMS PAR Scientists will support one of either formulation, filling, or visual
inspection (VI), although may support multiple areas during start-up phase. Upon the start of commercial production, this role's objectives include maintaining the validated state of applicable processes, establishing and monitoring
metrics/methods to ensure a state of capability and control, harmonization of control strategies across process
teams, evaluate process improvement, and serving as an escalation point for day-to-day operations issues. The role will also author and execute protocols as well as conduct root cause investigations. The principal role is a position
that develops and implements a technical agenda and is responsible for providing technical leadership for the
Parenteral Process Team. The principal role expected to serve as a mentor within the TSMS team and engage in
upstream and external to site activities related to parenteral manufacturing.
Key Objectives/Deliverables:
* Support the assigned Process Team (formulation, filling, or VI) as TSMS representative. • (Associate/Senior) Serve as floor-level support and technical interface for manufacturing components, equipment, and operations for the TSMS team.
* Represent Concord TSMS team for internal and external communications on a regular basis
* Lead risk management activities as it pertains to product/process
* Provide technical support to non-routine (e.g., deviation, complaint) investigations, including consultation on quality and stability issues
* Prepare and Review or approve, as required, relevant technical documents such as: Annual Product Reviews, Change Controls, Regulatory Submissions, Deviations, Validations, Procedures, PFDs, PFMEAs, etc.
* Develop, monitor, and appropriately react to established statistically based metrics in real-time to assess process variability and capability
* Identify opportunities and lead technical projects to improve process control and/or productivity
* Serve as interface with upstream suppliers and parenteral product networks
* Drive stability strategy for Concord products
* Provide Audit support as needed
* Identify opportunities and participate in projects to improve process control and/or productivity
Basic Qualifications:
* Bachelor's degree or higher an engineering, packaging science, or related field
Additional Skills/Preferences:
* Pharmaceutical and/or medical device manufacturing experience
* Root Cause Investigation Experience
* Proficiency with computer systems including Microsoft Office products, Veeva Vault, TrackWise, electronic batch records, and SAP
* Demonstrated successful leadership of cross-functional teams
* Strong interpersonal and teamwork skills
* Strong self-management and organizational skills
Additional Information:
* Role is Monday through Friday. Must be flexible in providing support to accommodate other inputs (production schedules, shutdowns, etc.). Occasional extended hour and /or off-hour work may be required.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (******************************************************** for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), en Able (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$66,000 - $171,600
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Auto-ApplySENIOR TOXICOLOGIST
Senior principal scientist job in Sacramento, CA
The Senior Toxicologist serves as the Chief of the Cancer Toxicology and Epidemiology Section (CTES), within the Reproductive and Cancer Hazard Assessment Branch (RCHAB). CTES provides technical support for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65), including identifying chemicals for consideration for listing as carcinogens under Proposition 65, conducting dose-response and exposure assessments, and developing carcinogen risk assessment guidance and methodology. CTES also provides technical assistance to other programs in the Office of Environmental Health Hazard Assessment (OEHHA), the Attorney General's Office, and other California government entities.
The Senior Toxicologist supervises the activities of the personnel in CTES and provides expert scientific and management supervision of Section projects by coordinating, as appropriate, with the Chief of RCHAB, and other programs within OEHHA. Duties include the direct supervision of Section staff, granting time off, and coordinating various projects involving other parts of the department. The incumbent will review the work of staff and will be responsible for the most sensitive documents prepared by the Section.
Please let us know how you heard about this position by taking a brief survey:
**************************************
LIST ELIGIBILITY - EXAMINATION PROCESS
List eligibility is established through an examination process in which one must apply and successfully pass the examination for the classification. If you have not established list eligibility for the Senior Toxicologist, please click on the link to the examination bulletin for more information - ********************************************************************************
You will find additional information about the job in the Duty Statement.
Working Conditions
OEHHA has a hybrid work environment that includes work in an office setting in a high-rise building and telework at home. Requires extended periods of reading and writing, frequently using computer workstations, and data and word processing software. Work in office space may not have direct natural lighting. Day trips and overnight travel may be required to attend meetings, public hearings, and/or to work with other governmental entities to complete projects and work assignments. May be required to travel to other locations for business related needs as necessary.
This position may be located either at 1515 Clay Street, 16th Floor, Oakland, or at 1001 I Street, 12th Floor, Sacramento, California.
Minimum Requirements
You will find the Minimum Requirements in the Class Specification.
* SENIOR TOXICOLOGIST
Additional Documents
* Job Application Package Checklist
* Duty Statement
Position Details
Job Code #:
JC-484890
Position #(s):
811-140-7943-006
Working Title:
Chief, Cancer Toxicology and Epidemiology Section
Classification:
SENIOR TOXICOLOGIST
$12,295.00 - $15,730.00
New to State candidates will be hired into the minimum salary of the classification or minimum of alternate range when applicable.
# of Positions:
1
Work Location:
United States
Telework:
Hybrid
Job Type:
Permanent, Full Time
Department Information
The Office of Environmental Health Hazard Assessment (OEHHA) values diversity, equity, and inclusion throughout the organization. We foster an environment where employees from a variety of backgrounds, cultures, and personal experiences are welcomed and can thrive. We believe the diversity of our employees is essential to inspiring innovative solutions. Together we further our mission to protect and enhance the health of Californians and our state's environment through scientific evaluations that inform, support and guide regulatory and other actions.
Join OEHHA to improve the lives of all Californians. OEHHA is a small agency that will provide lots of varied experience. OEHHA is responsible for developing and providing risk managers in state and local government agencies with toxicological and medical information relevant to decisions involving public health.
Department Website: ************************
This position may be eligible for hybrid telework under Government Code 14200 for eligible applicants residing in California, subject to the candidate meeting telework eligibility criteria set forth in the CalEPA telework policy and/or future program need. Employees not residing in California are not eligible for telework. Regardless of telework eligibility, all employees may be required to report to the position's designated headquarters location, as indicated on their duty statement, at their own expense.
Special Requirements
Electronic applications through your Cal Career Account are highly recommended.
We highly recommend electronic submission of applications. Applications Packages may be submitted electronically through your CalCareer Account by 11:59 p.m. on or before the above final filling date. Electronic applications submitted through your CalCareer Account are highly recommended and will be received faster that other methods of applying.
Application Instructions
Dates printed on Mobile Bar Codes, such as the Quick Response (QR) Codes available at the USPS, are not considered Postmark dates for the purpose of determining timely filing of an application.
Final Filing Date: Until Filled
Who May Apply
Individuals who are currently in the classification, eligible for lateral transfer, eligible for reinstatement, have list or LEAP eligibility, are in the process of obtaining list eligibility, or have SROA and/or Surplus eligibility (please attach your letter, if available). SROA and Surplus candidates are given priority; therefore, individuals with other eligibility may be considered in the event no SROA or Surplus candidates apply.
Applications will be screened and only the most qualified applicants will be selected to move forward in the selection process. Applicants must meet the Minimum Qualifications stated in the Classification Specification(s).
How To Apply
Complete Application Packages (including your Examination/Employment Application (STD 678) and applicable or required documents) must be submitted to apply for this Job Posting. Application Packages may be submitted electronically through your CalCareer Account at ********************** When submitting your application in hard copy, a completed copy of the Application Package listing must be included. If you choose to not apply electronically, a hard copy application package may be submitted through an alternative method listed below:
Address for Mailing Application Packages
You may submit your application and any applicable or required documents to:
Environmental Health Hazard Assessment Office
N/A
Attn: Julia Rollison - JC-484890
P.O. Box 67
1001 I Street, 12th Floor
Sacramento, CA 95812-0067
Address for Drop-Off Application Packages
You may drop off your application and any applicable or required documents at:
Environmental Health Hazard Assessment Office
N/A
Julia Rollison- JC-484890
P.O. Box 67
1001 I Street, 12th Floor
Sacramento, CA 95812-0067
10:00 AM - 05:00 PM
Required Application Package Documents
The following items are required to be submitted with your application. Applicants who do not submit the required items timely may not be considered for this job:
* Current version of the State Examination/Employment Application STD Form 678 (when not applying electronically), or the Electronic State Employment Application through your Applicant Account at ********************** All Experience and Education relating to the Minimum Qualifications listed on the Classification Specification should be included to demonstrate how you meet the Minimum Qualifications for the position.
* Resume is required and must be included.
* Statement of Qualifications - Please see Statement of Qualifications below.
* Other - Curriculum Vitae
Applicants requiring reasonable accommodations for the hiring interview process must request the necessary accommodations if scheduled for a hiring interview. The request should be made at the time of contact to schedule the interview. Questions regarding reasonable accommodations may be directed to the EEO contact listed on this job posting.
Desirable Qualifications
In addition to evaluating each candidate's relative ability, as demonstrated by quality and breadth of experience, the following factors will provide the basis for competitively evaluating each candidate:
* Knowledge and proficiency in general principles of toxicology, with an emphasis in the area of carcinogenesis.
* An understanding of the general principles of public health and risk assessment.
* Ability to critically review and evaluate highly complex scientific studies and other information relevant to carcinogen risk assessment.
* Knowledge of principles and techniques of effective supervision.
* Ability to produce high quality work products that clearly and concisely convey scientific findings and concepts.
* Ability to function effectively and work cooperatively in a team.
* Ability to communicate complex technical matters effectively in person and in writing.
* Ability to analyze situations accurately and take effective action in a timely manner.
* Ability to produce high quality written reports.
* Knowledge of statistical and dose-response modeling software.
Benefits
In addition to a compelling vision for California, the Office of Environmental Health Hazard Assessment offers competitive pay, benefits, and features for its workforce. To review the pay and benefits offered to California civil service staff, please review CalHR's website at *************************************************************
Contact Information
The Human Resources Contact is available to answer questions regarding the application process. The Hiring Unit Contact is available to answer questions regarding the position.
Human Resources Contact:
Julia Rollison
**************
***************************
Hiring Unit Contact:
Brian Brown
**************
************************
Please direct requests for Reasonable Accommodations to the interview scheduler at the time the interview is being scheduled. You may direct any additional questions regarding Reasonable Accommodations or Equal Employment Opportunity for this position(s) to the Department's EEO Office.
EEO Contact:
Cassaundra Willis
**************
******************************
California Relay Service: ************** (TTY), ************** (Voice) TTY is a Telecommunications Device for the Deaf, and is reachable only from phones equipped with a TTY Device.
APPLICATION INFORMATION
All applicable fields on the State Application Form (STD. 678) must be filled out completely. Clearly indicate on the Form STD. 678 in the field titled "Examination(s) or Job Titles for Which You Are Applying" the position as Senior Toxicologist - Job Code (JC)-460026 as indicated on this job announcement and your basis of eligibility (*list eligibility, lateral transfer, reinstatement, etc.). Employment history on your application must be complete with dates, description of duties and responsibilities for each position held, contact names and phone numbers of supervisors. Applicants who do not submit all of the required documentation (incomplete application package) may be eliminated from the selection process.
Statement of Qualifications
The Statement of Qualifications (SOQ) serves as documentation of your ability to present information clearly and concisely in writing. The SOQ is a narrative discussion, not a bulleted summary. Please answer each of the following questions for the SOQ. Identify each response with the number of the SOQ question, single-spaced, and using Arial 12-point font. The SOQ should be no more than three (3) pages in length.
* Describe how your education, experience, and other skills qualify you to effectively direct a multidisciplinary team of scientists to conduct scientifically rigorous, accurate, and complete evaluations and analyses of scientific studies that provide evidence relevant to the evaluation of cancer hazards and/or cancer risks of specific chemicals and chemical substances.
* Discuss your role and contributions to a project that involved the evaluation and analysis of a complex set of toxicological issues and data related to assessing cancer hazards and/or cancer risks. Include a brief description of the methods applied, the analyses conducted, and the key outcomes of the project.
* Describe your experience giving oral presentations on issues related to cancer hazards and/or cancer risks at scientific conferences, meetings of expert panels, or other public meetings.
Equal Opportunity Employer
The State of California is an equal opportunity employer to all, regardless of age, ancestry, color, disability (mental and physical), exercising the right to family care and medical leave, gender, gender expression, gender identity, genetic information, marital status, medical condition, military or veteran status, national origin, political affiliation, race, religious creed, sex (includes pregnancy, childbirth, breastfeeding and related medical conditions), and sexual orientation.
It is an objective of the State of California to achieve a drug-free work place. Any applicant for state employment will be expected to behave in accordance with this objective because the use of illegal drugs is inconsistent with the law of the State, the rules governing Civil Service, and the special trust placed in public servants.
Sr Scientist/ Associate Principal Scientist, LCMS Platforms
Senior principal scientist job in Pleasanton, CA
Job DescriptionBenefits:
401(k)
401(k) matching
Bonus based on performance
Dental insurance
Free food & snacks
Health insurance
Paid time off
Parental leave
Vision insurance
Position Summary:
Crystal Bio Solutions is a CRO providing global-standard services in GLP/GCLP bioanalysis and biomarker. Our clients include multinational pharmaceutical companies and biotech companies.
The Bioanalysis & Biomarkers Department specializes in Method Development, Method Validation, GLP/GCLP Bioanalysis for PK, and biomarkers. The team has successfully supported non-GLP, GLP (non-clinical) and GCLP (clinical) projects. The role is responsible for providing bioanalytical support for both pre-clinical and clinical projects and partnering with our clients for project success.
Key Responsibilities:
Independently propose assay design and/or strategy, develop, validate, conduct, and troubleshoot LCMS-based bioanalytical methods for the quantification of small molecule (and its metabolites) and biologics (e.g. ADC, mAB, protein, peptide, oligonucleotide etc) in support of PK, and Biomarker measurement
Conduct or oversee GLP/GCLP sample analysis and data reporting.
Present and interpret data internally and/or externally as needed.
Serve as the Principal Investigator responsible for interaction with the client from the study design to scheduling, conducting, reporting, and transferring data. Ensure responsiveness to the client, timely delivery, and overall customer satisfaction.
Serve as Subject Matter Expert (SME) for LCMS platform
Ensure GLP/GCLP compliance, including accurate documentation and adherence to established procedures
Author and/or review key regulatory documents, validation plans and reports, laboratory data, and technical reports.
Provide technical leadership for LC-MS as a Subject Matter Expert, and mentor junior scientists.
Assist in improving policies, procedures, work instructions and SOPs
Understand and adhere to corporate standards regarding code of conduct, Environment Health & Safety (EHS), and GLP/GCP/GDP compliance.
Perform other related duties as assigned
Qualifications & Educational Requirements:
Ph.D., M.Sc., M.A., B.A., in Biology, Immunology, Chemistry, Pharmacology, or other related scientific fields required, including a minimum of 4+(Ph.D.), 9+(Masters) or 12+(Bachelors) years of CRO/Pharma/Biotech experience.
Hands-on experience and strong knowledge of GLP/GCLP bioanalysis.
Experienced with GLP/GCLP LCMS method development and validation for PK and/or biomarker analysis.
Functional experience utilizing LIMS and QMS systems for GLP/GCLP bioanalysis
Established record of independent achievement of objectives and timelines while maintaining high work quality.
Effective in team environments co-workers, managers, and clients
Must be goal-oriented, compliance-ensured, quality-conscientious, and client-focused.
Effective writing and communication skills are required.
Experience in large molecule LCMS analysis (e.g. ADC, mAB, protein, peptide, oligonucleotide etc) preferred.
Familiarity with additional bioanalytical platforms (e.g. LBA, PCR, Flow Cytometry) preferred.
Supervisory experience in both project and talent (people) management is preferred.
Pay Transparency Statement
Title and compensation will be based on experience ( Senior Scientist / Associate Principal Scientist).
At CP, your base pay is only part of your overall total compensation package. At the time of this posting, this role typically pays an annual base salary between $110,000 and $160,000 per year. The range displayed reflects the minimum and maximum target for new hires. Actual pay may be more or less than the posted range. Factors that influence pay include the individual's skills, qualifications, education, experience, and the position level and location.
Agency Notice Direct Applicants OnlyWe are currently handling this recruitment directly and are not engaging with external recruiters or staffing vendors for this position. Thank you for your understanding.
Scientist - Bioanalysis & Biomarkers- LCMS
Senior principal scientist job in Pleasanton, CA
Purpose
Amador Bioscience (AmadorBio) is a Translational & Clinical Pharmacology CRO providing global-standard services in quantitative clinical pharmacology, GLP/GCLP bioanalysis, clinical research, and regulatory filing to leading biopharmaceutical companies. Our clients include multinational pharmaceuticals and mid- and small-size biotech companies.
Amador Laboratory Services Division specializes in bioanalysis (PK/PD/ADA), biomarkers, assay development & validation, and sample analysis. The team has successfully supported multiple non-GLP, GLP (nonclinical) and GCLP (clinical) projects. To meet the needs of business growth, we are looking for a highly motivated, experienced scientist/senior scientist to join our passionate team to partner with our clients for success. The successful candidate will be responsible for providing bioanalytical supports for both pre-clinical and clinical projects and will report to the Laboratory Head.
Role and Responsibilities
Develop, validate, conduct, and troubleshoot UHPLC and LC-MS analytical methods to quantitate large molecules and metabolites in biological fluids
Present/interpret data internally and/or externally as needed.
Participate in interactions with clients and ensure overall customer satisfaction.
Interacts with QA to ensure all audit findings are addressed in a timely fashion.
Author and/or review key regulatory documents, laboratory data, and technical reports.
Assist with the oversight of the laboratory and mentor junior staff.
Assist in establishing and improving all policies, procedures and required SOP documentation.
Understand and adhere to corporate standards regarding code of conduct, safety, and GLP/GCP/GDP compliance.
Ensure and reviews lab maintenance activities and maintains a clean and safe lab environment
Develop, write, and review protocols and SOPs.
Participate in regulatory compliance activities
Perform all other related duties as assigned
Qualifications and Education Requirements
Ph.D., Master's, or Bachelor's degree in biology, immunology, chemistry, pharmacology, or other related scientific fields required.
Requires a minimum 0-9 years of relevant experience in a CRO or drug-development environment.
Ability to work independently and have good attention to details.
Good knowledge of regulated bioanalysis. GLP/GCLP experience preferred.
Ability to achieve objectives/timelines through collaborative efforts with coworkers, managers, and clients.
Must be goal-oriented, quality-conscientious, and client-focused.
Effective written and verbal communication skills.
Experienced with LCMS or tandem Mass-Spec method development and validation for PK and/or biomarker analysis.
Preferred Skills
Proficient in MS Office
Watson LIMS
Strong knowledge of GLP/GCLP regulations
Salary range is from $105,000 to 120,000
Auto-ApplyScientist II
Senior principal scientist job in Pleasanton, CA
Our client, a world leader in diagnostics and life sciences, is looking for a "Scientist II” based out of Pleasanton, CA.
Job Duration: Long term Contract (Possibility Of Further Extension)
Pay Rate: $55/hr on W2
Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K
The BioSpecimen Acquisition and Management function is a centralized service function which supports the acquisition, characterization, and management of biological materials, as well as build of select panels for clinical research and cultivation and characterization of various Microorganisms and Mammalian cell lines. The Scientist II position will facilitate the daily operations associated with fulfilling service requests for Culture Collection and panel activities, while providing best -in -class simple biological solutions to our customers to drive innovation.
Responsibilities:
Under minimal supervision, executes assigned project activities using established procedures and applying scientific knowledge and accumulated experience to complete projects involving manipulating human cell lines, microorganism and/or other biological material.
Perform standard recombinant DNA techniques including cloning, restriction digestion, ligation, and transformation of bacteria.
Grow bacterial cultures under sterile conditions to ensure successful transformation and plasmid propagation.
Analyze plasmid DNA and RNA transcripts for purity, concentration, and quality.
Qualifications:
Bachelor's degree in Molecular Biology, Cellular Biology, or Microbiology or related field and 4+ years of relevant experience.
Master's Degree in Molecular Biology, Cellular Biology, or Microbiology or related field and 2+ years of relevant experience.
Experience with aseptic techniques and bacterial culture or cell culture.
Must be able to manually manipulate samples (plating, pipetting, labeling and vialing) on a routine basis.
Experience with cloning techniques including plasmid design and preparation, restriction enzyme digestion, ligation and bacterial transformation and processing.
Experience in performing nucleic acid extractions (DNA/RNA), quantification, amplification and characterization using Qubit, Nanodrop, Gel electrophoresis, PCR machines etc.
Must be able to work in a laboratory environment on a daily basis under BSL -2 laboratory conditions. May work a variety of infectious human material (HxV, pathogenic bacteria, or engineered material, etc) and sample types (blood, serum, urine, stool etc).
Experience with LIMS software, eLN and JMP (Preferred).
If interested, please send us your updated resume at
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