Senior associate scientist job description

Event Information:
Thursday, October 20th from 3:00 - 5:30 pm est

Reserve your spot to speak with the Pfizer team at the Virtual Hiring Event. Attend from your computer or smartphone. No app download required. Click ""Apply"" to complete your registration for the virtual event.

About the Position:

This is a laboratory-based position within the Vaccine Research and Development Analytical Development group. The candidate will provide support to the Critical Reagent and Sample Management group in the form of critical reagent management and documentation, assay development to support reagent characterization, in-vivo study coordination, and sample management.

Requirements:

• BS or MS or equivalent degree required with background in molecular biology (preferred) or chemistry with 1-3 years relevant experience.
• Lab experience required.
• Excellent organizational and communication skills is essential.
• Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is required.
• Strong verbal and written communication skills.

About Pfizer:

At Pfizer, we re driven to discover the cure driven to significantly improve the lives of everyone...everywhere. If you re similarly driven, you ll find there s no better place to begin and continue your career than at Pfizer.

Science is the foundation of our company. This is why it s no surprise that our scientists are among the best in the world. We arm them with the resources, technology, and facilities they need to solve some of the world s most complex health challenges. So, it s no wonder that the most driven scientists in the world choose to do their life s passion at Pfizer.

Join us and you ll partner with colleagues of diverse backgrounds and abilities, people who contribute to all aspects of what we do from drug development to marketing, technology to sales, and so much more.

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1) Develop highly sensitive, selective, and reproducible methods for the analysis of small molecule drugs in various biological matrices

2) Plan, execute, analyze, and document experiments

3) Conduct trouble-shooting and instrument maintenance of LC/MS

4) Perform analytical and pharmacokinetic/pharmacodynamic data analysis and metabolite identification research

5) Present and discuss data internally and externally, write reports

6) Work cohesively with a team of scientists and lead projects

7) QC and Review data package and reports

8) Supervise, train, and coach junior scientists

Essential Duties & Responsibilities

List below the major areas of responsibility of the job in descending order of importance (most important to least important). Indicate the approximate percentage of time spent on each responsibility (note the total of all percentages must equal 100%, 3-5 responsibilities is normal but may vary). Under each responsibility, summarize the specific duties required to perform the job. Give as much detail as necessary to fully explain the job and consider:

• Whether the reason the job exists is to perform that function and whether removing the function would fundamentally change the job;
• Whether serious consequences would arise if someone in this job is not required to perform a particular function/s;

• The number of employees available to perform the function or among whom the function can be distributed; and,
• The degree of expertise or skill required to perform the function.

% of Time

Duties & Responsibilities

15%

Develop highly sensitive, selective and reproducible methods for the analysis of small molecule drugs in various biological matrices

15%

Plan, execute, analyze, and document experiments. Conduct trouble-shooting and instrument maintenance of LC/MS

15%

Perform analytical and pharmacokinetic/pharmacodynamic data analysis and metabolite identification research

20%

Present and discuss data internally and externally, write reports

15%

Work cohesively with a team of scientists and lead projects

20%

QC and Review data package and reports. Supervise, train, and coach junior scientists

100%

Minimum Job Requirements & Qualifications

Describe the minimum level of formal education and experience required to successfully perform the job
as well as any required certification, licensure or registration. KSAs may include language requirements, required computer ability, communications skills, etc.

Educational/Training Requirement:

Ph.D degree in related scientific discipline with 4+ years industrial experience. or M.S degree with 8+ years relevant experience.

Experience:

4+ years industrial experience in related scientific field.

Licenses/Certifications (if applicable) :

• 
  
  

Knowledge, Skills, and Abilities (KSAs):

• 
  
  

Supervisory Responsibility

List the job titles that directly report to this job (formal supervision).

Travel Requirements

Estimate the percentage and nature (i.e., domestic or international) of travel; if no travel is required, indicate 0%). 5%

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

Americans with Disabilities Act (ADA)
PHYSICAL DEMANDS and work environment CHECKLIST

PHYSICAL DEMANDS

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. These may include lifting, pushing, climbing, degree of eyestrain, sitting for extended periods of time, prolonged standing, etc. Frequency refers to the amount of time one is engaged in the activity; please estimate time by checking the appropriate boxes.

Physical Demands

Physical Demand

None

Rarely

Occasionally

Frequently

Constantly

Weight

Standing

x

Walking

x

Sitting

x

Lifting

x

Up to 10 pounds

Carrying

x

Up to 10 pounds

Pushing

x

Choose weight

Pulling

x

Choose weight

Climbing or balancing

x

Stooping, kneeling, crouching
or crawling

x

Reaching with hands/arms

x

Using hands to finger, handle, grasp or feel

x

Talking

x

Hearing

x

Tasting or smelling

x

Repetitive motions

x

Ginkgo's mission is to make biology easier to engineer. We are constructing, editing, and redesigning the living world in order to answer the globe's growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms. Today, our foundry is developing over 40 different organisms to make different products across multiple industries.

Ginkgo is continuously crossing new frontiers of biological engineering and we have a record of delivering what was, until recently, thought impossible. Now, our expansion into mammalian cell engineering promises to push our boundaries even further, and so we're looking for pioneering engineers to make Ginkgo's new mammalian cell foundry a success.

While cell and gene therapies have seen remarkable success in the clinic, we are at the dawn of a new age in our ability to precisely control gene expression. We're searching for an outstanding scientist to join our team to execute synthetic promoter discovery screens in mammalian cells. In particular, we are looking for people with experience using recombinase-mediated cassette exchange and other pooled screening techniques. In this role, you will bring your fluency with molecular biology techniques and mammalian cell culture to help optimize and execute RMCE experiments in the context of cell and gene therapy. To be successful in this role, you will think big and execute systematically. You will work closely with a cross-functional technical team to contribute to the optimization of selection strategies, design of barcoding strategies and analysis methods. You will put your organizational and communication muscles to work every day as you work closely with teams across Ginkgo. The level of the position is flexible depending on prior experience.
Please note this position is located at our Cambridge site

#LI-MB1
ResponsibilitiesContribute to the optimization of RMCE-based integration methods Work with teammates to execute massively parallel pooled screens Independently analyze and interpret experimental results Work with fellow Ginkgo engineers to integrate screens into Ginkgo's automation and software platforms Maintain laboratory records using Ginkgo internal software tools Contribute to laboratory organization and maintenance Contribute to mammalian team growth and development
Desired Experience and CapabilitiesTitle/responsibility commensurate with experience - open to diverse backgrounds and degrees in biology, bio-engineering, or related field Undergraduate degree and 2 years of hands on post-degree research experience, OR, masters degree and 1 year of hands on post-degree research experience, OR PhD and relevant hands on research experience Experience with mammalian cell engineering or pooled screens, preferably using recombinase-mediated methods Exposure to mammalian synthetic biology, including mammalian construct design, gene editing and/or high-throughput screening Ability to work with interdisciplinary teams in a fast-paced, high-growth environment For more senior candidates, excellent project management skills, with the ability to achieve milestones in a timely manner and communicate project status with stakeholders
Additional Preferred Requirements (desired, but not essential) Familiarity with cell and gene therapy Familiarity with laboratory automation Familiarity with data analysis platforms such as Python, R, and/or JMP Please note: this role requires the willingness and ability to share occasional weekend cell culture duties
To learn more about Ginkgo, visit www.ginkgobioworks.com/press/ or check out some curated press below:
What is it really like to take your company public via a SPAC? One Boston biotech shares its journey (Fortune)
Ginkgo Bioworks resizes the definition of going big in biotech, raising $2.5B in a record SPAC deal that weighs in with a whopping $15B-plus valuation (Endpoints News)
Ginkgo Bioworks CEO on scaling up Covid-19 testing: ‘If we try, we can win' (CNBC)
Ginkgo raises $70 million to ramp up COVID-19 testing for employers, universities (Boston Globe)
Ginkgo Bioworks Redirects Its Biotech Platform to Coronavirus (Wall Street Journal)
Ginkgo Bioworks Provides Support on Process Optimization to Moderna for COVID-19 Response (PRNewswire)
The Life Factory: Synthetic Organisms From This $1.4 Billion Startup Will Revolutionize Manufacturing (Forbes)
Synthetic Bio Pioneer Ginkgo Raises $290 Million in New Funding (Bloomberg)
Ginkgo Bioworks raises $350 million fund for biotech spinouts (Reuters)
Can This Company Convince You to Love GMOs? (The Atlantic)

We also feel that it's important to point out the obvious here - there's a serious lack of diversity in our industry, and that needs to change. Our goal is to help drive that change. Ginkgo is deeply committed to diversity, equity, and inclusion in all of its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.

We're developing a powerful biological engineering platform, so we must remain mindful of the many ways our technology can - and will - impact people around the world. We care about how our platform is used, and having a diverse team to build it gives us the best chance that it's something we'll be proud of as it continues to grow. Therefore, it's critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees and employment applicants.