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  • Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite)

    Cedars-Sinai 4.8company rating

    Associate scientist job in San Diego, CA

    The Svendsen Lab at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for a Postdoctoral Scientist to join the team! When the work you do every single day has a crucial impact on the lives of others, every effort, every detail, and every second matters. This shared culture of happiness, passion, and dedication pulses through Cedars-Sinai, and it's just one of the many reasons why we rank as one of the top hospitals in the nation by U.S. News & World Report. Are you ready to be a part of breakthrough research? The mission of the Svendsen Laboratory is to study neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD), and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Clive Svendsen, PhD, has significant experience in studying these diseases over the last twenty years and is merging his experience with the use of groundbreaking technologies, such as inducible pluripotent stem cells (iPSC cells). To learn more, please visit Svendsen Research Lab | Cedars-Sinai (cedars-sinai.edu). The Postdoctoral Scientist works independently but in close cooperation and consultation with the Principal Investigator and other Research Scientists. The incumbent will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols. Analyzes and interprets data. Please note that this position is onsite. Primary Job Duties and Responsibilities: May assist in the preparation of grant proposals, but is not responsible for generating grant funds. May participate in publications and presentations as author or co-author. Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. Analyzes interpret, summarizes, and compiles data. Operates and maintains equipment and instruments. May observe MD-patient or MD-human research subject interactions as they pertain directly to research being performed. Qualifications Education: Doctorate (MD, PhD, VMD, or DDS) in the area directly related to the field of research specialization. Experience and Skills: Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. Works independently on research projects designed by a mentor (typically the PI) within area of specialization. Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, analysis, operation, and maintenance of specialized equipment. Scheduling flexibility including evening, weekend, and holiday rotation commitments may be necessary. Travel may be required. Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students. Excellent written and oral communication skills are essential. Knowledge of safety standards and maintenance of specialized equipment. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13004 Working Title : Postdoctoral Scientist - Svendsen Lab - Regenerative Medicine Institute (Onsite) Department : Research - RMI Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Postdoctoral Scholar Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $62,400.00 - $93,600.00
    $62.4k-93.6k yearly 23h ago
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  • Sr. Staff Data Scientist

    Northrop Grumman Corp. (Au 4.7company rating

    Associate scientist job in San Diego, CA

    At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems that impact people's lives around the world today, and for generations to come. Our pioneering and inventive spirit has enabled us to be at the forefront of many technological advancements in our nation's history - from the first flight across the Atlantic Ocean, to stealth bombers, to landing on the moon. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aeronautics Systems has an opening for a Staff Data Scientist to join our team of qualified, diverse individuals within the Advanced Manufacturing Technology Organization. This position can be located in San Diego or Palmdale, CA; Clearfield, UT; St. Augustine or Melbourne, FL Locations. In this role, you will Provide leadership/direction to ensure technology initiatives and opportunities for process improvements are systematically identified, pursued, and supported. Develop architectures and concepts for advanced digital technologies with a focus on implementation within Northrop Grumman Interact with customers (internal and external) Reach out and work with colleges, universities, government, supplier as part of development and improvement projects Provide leadership/direction to ensure technology initiatives and opportunities for process improvements are systematically identified, pursued, and supported. Introduce and develop new technologies for the manufacturing floor Lead projects consisting of cross functional teams of high performing engineers developing advanced systems designs and concepts. Provide technical leadership and oversight to achieve efficient, effective, and innovative Engineering solutions Apply new technologies as well as common designs and products enabling rapid development, prototyping and affordable solutions. Basic Qualifications Bachelor of Science degree in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 14 years of experience in engineering; OR Master of Science degree in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 12 years of experience in engineering; OR PhD in a Science, Technology, Engineering or Mathematics (STEM) discipline from an accredited university with 10 years of experience in engineering. Secret Clearance Periodic Re-investigation within the last 5 years Knowledge of data gathering, cleansing and transformation techniques Experience with common data science toolkits/languages such as python/R, scikit-learn, PyTorch/TensorFlow, matplotlib, numpy, C++ or python Exceptional analytical skills. Familiarity with cloud Knowledge and experience performing model uncertainty analysis, error modelling, and/or error propagation. Knowledge of best practices in data analysis. Excellent interpersonal and communication skills. Experience developing mathematical models of dynamic systems from first principles. Knowledge and experience with System Identification techniques using statistical methods to validate dynamic system models with test data. Experience performing parametric and non-parametric system identification. Experience with data acquisition systems and/or post-processing experimental test data. Knowledge and experience performing model uncertainty analysis, error modelling, and/or error propagation. Fluent with Python or Matlab. Documenting processes and maintaining data records. Preferred Qualifications Secret Clearance Periodic Re-investigation within the last 5 years Special Access Program (SAP) Current Proficient with cloud Experience in hardware/software integration of manufacturing systems Experience with querying databases and defining schemas (MS SQL) with the ability to perform data analysis and report findings Proficient in Microsoft Excel and PowerPoint Experience with high volume production ETL pipelines Experience with production assembly/fabrication including Digital Transformation, Augmented Reality/Virtual Reality, Systems Integration, IIoT, RFID, Cloud Based Applications, and/or production manufacturing operations Working knowledge of classified information systems infrastructure Digital Manufacturing experience Architecture, Design & Integration experience for engineering systems and software Technical Writing capability Project / Program Management skills (proposal creation, scheduling, budget tracking) Strong Familiarity with Process Development & Controls Ability to lead through, overcome and adapt to obstacles and challenges Ability to deal effectively with change and challenges and helps others to do the same Ability to travel 10-15% of the time Primary Level Salary Range: $178,600.00 - $310,300.00 The above salary range represents a general guideline; however, Northrop Grumman considers a number of factors when determining base salary offers such as the scope and responsibilities of the position and the candidate's experience, education, skills and current market conditions. Depending on the position, employees may be eligible for overtime, shift differential, and a discretionary bonus in addition to base pay. Annual bonuses are designed to reward individual contributions as well as allow employees to share in company results. Employees in Vice President or Director positions may be eligible for Long Term Incentives. In addition, Northrop Grumman provides a variety of benefits including health insurance coverage, life and disability insurance, savings plan, Company paid holidays and paid time off (PTO) for vacation and/or personal business. The application period for the job is estimated to be 20 days from the job posting date. However, this timeline may be shortened or extended depending on business needs and the availability of qualified candidates. Northrop Grumman is an Equal Opportunity Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO and pay transparency statement, please visit *********************************** U.S. Citizenship is required for all positions with a government clearance and certain other restricted positions. #J-18808-Ljbffr
    $96k-147k yearly est. 4d ago
  • Lead In Vitro Pharmacology Scientist - GPCR Drug Discovery

    Crinetics Pharmaceuticals, Inc. 3.9company rating

    Associate scientist job in San Diego, CA

    A biopharmaceutical company in San Diego seeks a Principal Scientist to lead an in vitro pharmacology team. Candidates should have a Ph.D. and over 8 years in drug discovery, particularly with GPCRs. Responsibilities include designing assays, managing a team, and collaborating on research projects. The competitive salary ranges from $158,000 to $197,000, with comprehensive benefits including health insurance and PTO. #J-18808-Ljbffr
    $158k-197k yearly 6d ago
  • Lead Scientist, Targeted Drug Delivery & Receptor Biology

    Califesciences

    Associate scientist job in San Diego, CA

    A leading biotechnology company is seeking a Principal Research Scientist to focus on targeted drug delivery, including nucleic acid therapies. Located at their state-of-the-art site in San Diego, the successful candidate will have strong expertise in receptor biology and targeted drug delivery. The role includes developing strategic research plans, collaborating with cross-functional teams, and maintaining scientific rigor. This position offers a pay range of $136,000 - $204,000 with additional benefits, such as bonuses, equity awards, and comprehensive health coverage. #J-18808-Ljbffr
    $136k-204k yearly 5d ago
  • Principal CADD Scientist

    Genesis Therapeutics

    Associate scientist job in San Diego, CA

    Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Principal CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US. What You Will Do (Key Responsibilities) Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents. Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts. Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches. Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making. Adapt to a fast-paced environment where innovation and quick iteration are encouraged. What you'll bring PhD in Computational Chemistry, Structural Biology, or a related field. This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD. Deep understanding of structure-based drug design and protein-ligand interactions. Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite. Minimum of 5+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs. Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists. We are open to remote team members too. What we offer Competitive Pay Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) Stock Option Eligibility 401(k) Plan Open PTO Policy Paid Company Holidays Subsidized lunch and snacks at our offices Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets. Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer. #J-18808-Ljbffr
    $112k-173k yearly est. 4d ago
  • Lead Scientist, In Vitro Antibody Display & Discovery

    Eli Lilly and Company 4.6company rating

    Associate scientist job in San Diego, CA

    A leading global healthcare firm in San Diego is seeking a highly motivated scientist to contribute to biotherapeutics development. The successful candidate will discover and engineer antibodies, oversee experiments, and utilize various molecular biology techniques. Applicants should have at least 6 years of relevant experience and a strong background in flow cytometry. This position offers competitive compensation ranging from $110,250 to $187,000 along with comprehensive benefits. #J-18808-Ljbffr
    $110.3k-187k yearly 5d ago
  • Process Development Associate

    Mastech Digital 4.7company rating

    Associate scientist job in San Diego, CA

    • Primarily responsible for commercial manufacturing. Also responsible for the transfer of manufacturing processes from R&D to Manufacturing and continuous improvement of existing processes. Essential Duties and Responsibilities The incumbent may be asked to perform other function-related activities in addition to the below mentioned responsibilities as reasonably required by business needs. • Maintains the Pilot Plant laboratory under cGMP conditions. • Produces development, pilot, and production materials per written instructions. • Completes ERP transactions. • Stocks and maintains the laboratory supplies. • Keeps accurate records and documentation. • Completes laboratory work and associated paperwork by assigned completion dates. • Produces notebook materials per written instructions. • Develops manufacturing processes for transfer to Manufacturing. • Assists with execution of process validation of new and existing manufacturing processes. • Improves manufacturing processes. • Completes cycle counts. • Washes lab ware. Qualifications Education • Bachelor's degree (sciences) Experience • 1+ years' experience preferred Skills • Basic knowledge of QMS (Quality Management System)/GMP requirements Must follow all applicable FDA regulations and ISO requirements.
    $70k-86k yearly est. 2d ago
  • In Vivo Research Associate II - Large Animal

    Proven Recruiting 4.3company rating

    Associate scientist job in Carlsbad, CA

    In Vivo Research Associate II/III, Large Animals (Contract to Hire) Looking to hone your animal surgery skills? One of San Diego's leading biotech companies is looking for a competent, reliable Research Associate to add to their dynamic team. This role offers the opportunity to build upon the foundation you've already laid in your industry experience and refine your in-vivo surgical skills. Don't miss this rare opportunity to learn from top professionals, grow into a more senior role, and excel in a challenging and supportive environment. What you will do: Administer test substances by various dosing methods, perform catheter placements, and prepare study activities. Manage and observe animals pre/post-surgery for general health and well-being. Collection of biological specimens including but not limited to skin, tissue, and blood from all animal species onsite. Who you are: AS OR BS with at least 4 years of experience with medical device studies or similar. Must have experience handling large animals (pigs, sheep, goats, rabbits, etc) Experience with dosing/injections (IM, SubQ, IV, IP, oral) Experience in a surgical environment is preferred. What does this position pay? Compensation is determined by several factors which may include skillset, experience level, and geographic location. The expected range for this role is $28.00 to $35.00 per hour. Please note this range is an estimate and actual pay may vary based on qualifications and experience. Please email your resume to sshields@provenrecruiting.com if you'd like to work alongside some of the finest professionals in the Life Sciences industry! Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!
    $28-35 hourly 4d ago
  • Associate Scientist - Assay Development

    Plantible Foods 3.8company rating

    Associate scientist job in Vista, CA

    How you will contribute: We are seeking a passionate and mission-driven Associate Scientist - Assay Development with passion for development, execution, and continuous improvement of the most critical assays and experimental methods in our drive towards producing the highest quality functional plant protein with exceptional yield and quality. This individual will lead efforts in our strain, nutrient, and environmental screens to optimize growth, protein production, and extraction while aiding in standardization of scale-down assay throughput & quality with fellow Scientists and Engineers. The individual will have the opportunity to make an immediate and sustainable impact in the development of the company. What you will be working on: Streamline assay development and assay throughput for key R&D projects related to plant strain screening, protein purification & extraction, odor and flavor modification, and protein functionality testing. Drive operational efficiency, precision, and scientific rigor to streamline bottlenecks in current experimental methods with a move towards standardization of methods and improved experimental outcomes. Leverage statistics and statistical design of experiments (DoE) to identify single and multi-factor variables that drive key metrics of interest as it relates to plant growth rate, protein production, protein extraction efficiency, and functional properties related to functionality, flavor, odor and color. Develop new and innovative experimental and scale-down assays to mimic plant growth and downstream processing. Implement improved analytical methods (chromatography, spectroscopy, etc.) to assess the effectiveness and robustness of extraction processes. Leverage these insights and in-process data to troubleshoot current processes and provide insights for the development of future research. What you bring to Plantible: B.S. or M.S in Biochemistry, Chemistry, Chemical Engineering or Bioengineering. 3 to 5+ years of industry experience in assay development in an industrial environment. Excellent laboratory skills and a passion for impacting R&D outcomes through experimentation where solid data is the ultimate influencer. Assay development experience in a diversity of applications where method improvement and standardization drove improved efficiency and outcomes. A willingness to solve problems using a combination of clever scientific approaches, rigorous and coordinated execution, and a bias to action. Relevant experience with screening photosynthetic organisms and/or protein production in varied organisms is preferred. Ability to learn quickly, solve complex problems and have excellent data analysis/interpretation skills. Excellent verbal and written communication and presentation skills. Being a self-starter and able to respond creatively and simply to continuous change and steady growth environment. Thrive in a fast-paced environment where the primary focus is on simplification and optimization. Choose Plantible Foods Joining Plantible means contributing to a sustainable future for all. We are a venture backed startup that is both spreading happiness amongst our employees and to current and future generations. We believe diversity creates uniqueness. Our team is composed of highly talented people with different interests and hobbies, which makes for a rich working environment. At Plantible we are continually working on our offerings to foster the best team. Check it out! Competitive health and wellness benefits Medical, Dental and Vision Insurance Discretionary Unlimited PTO Program Paid Holidays 401k Program Career Stipend Career development and growth opportunities Working in a rapidly growing, flexible and entrepreneurial environment Team building and company-wide events Financial support with your relocation, if necessary, ensuring a smooth transition Plantible Foods is an equal employment opportunity employer. Candidates are considered for employment without regard to race, creed, color, national origin, age, sex, religion, ancestry, veteran status, marital status, gender identity, sexual orientation, national origin, liability for military service, or any other characteristic protected by applicable federal, state, or local law. If you are interested in learning the status of your application, please note you will be contacted directly by the appropriate human resources contact person if you are selected for further consideration. Plantible Foods reserves the right to defer or close a vacancy at any time. If you feel your skill set does not meet all listed qualifications for the role, we still encourage you to apply. As we continue to grow our company, we are seeking a range of candidates and would gladly consider you for other current or upcoming roles that may be a fit!
    $74k-112k yearly est. 60d+ ago
  • Gas Chromatography Product Development Scientist

    Teledyne 4.0company rating

    Associate scientist job in San Diego, CA

    **Be visionary** Teledyne Technologies Incorporated provides enabling technologies for industrial growth markets that require advanced technology and high reliability. These markets include aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, deepwater oil and gas exploration and production, medical imaging and pharmaceutical research. We are looking for individuals who thrive on making an impact and want the excitement of being on a team that wins. **Job Description** **Job Summary:** TAPI is seeking a highly experienced Scientist, with a proven record of developing Gas Chromatography Instrumentation, to join our Research and Development team. This role will focus on the development of new GC-based instrumentation to support innovation in analytical chemistry and production workflows. The ideal candidate will bring deep expertise in gas chromatography, method development, and instrumentation, along with a strong background in production or R&D environments. **Key Responsibilities** + Lead the design and development of advanced gas chromatography (GC) methods and instrumentation. + Operate, maintain, and troubleshoot GC instruments including FID, DBD, FPD, and PID detectors. + Collaborate with cross-functional teams to support product development and quality assurance. + Perform sample preparation, calibration, and quantitative analysis with high precision. + Document and validate analytical methods in compliance with internal and regulatory standards. + Mentor junior technicians and contribute to technical training initiatives. + Communicate findings clearly through technical reports and presentations. **Minimum Qualifications** Education: Bachelor of Science (B.Sc.) in Chemistry, Biochemistry, Analytical Chemistry, or a related scientific field. Experience: Minimum of 10 years of relevant work experience in a R&D or Manufacturing environment. Technical Expertise: - Proficiency in GC method development, validation, and troubleshooting. - Proven experience with GC instruments including FID, DBD, FPD, and PID. - Familiarity with chromatography data systems such as Chromperfect . - Strong understanding of sample preparation, calibration, and quantitative analysis. Soft Skills: - Exceptional analytical thinking and attention to detail. - Excellent written and verbal communication skills. **Preferred Qualifications** + Experience in developing GC technologies for novel applications. + Knowledge of regulatory standards and documentation practices (e.g., cGMP, SOPs). + Ability to work independently and manage multiple projects simultaneously. **Why Join TAPI?** At TAPI, you'll be part of a dynamic team driving innovation in analytical science. We offer competitive compensation, a collaborative work environment, and opportunities for professional growth. **Salary Range:** $113,600.00-$151,400.000 **Pay Transparency** The anticipated salary range listed for this role is only an estimate. Actual compensation for successful candidates is carefully determined based on several factors including, but not limited to, location, education/training, work experience, key skills, and type of position. Teledyne conducts background checks on qualified applicants who receive a conditional offer of employment in accordance with applicable laws, regulations and ordinances. Background checks may include, but are not limited to, education verification, employment history and verification, criminal convictions, Motor Vehicle Report (MVR & driving history), reference check, credit checks/credit history and drug testing. All qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. Teledyne and all of our employees are committed to conducting business with the highest ethical standards. We require all employees to comply with all applicable laws, regulations, rules and regulatory orders. Our reputation for honesty, integrity and high ethics is as important to us as our reputation for making innovative sensing solutions. Teledyne is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, age, or any other characteristic or non-merit based factor made unlawful by federal, state, or local laws. You may not realize it, but Teledyne enables many of the products and services you use every day **.** Teledyne provides enabling technologies to sense, transmit and analyze information for industrial growth markets, including aerospace and defense, factory automation, air and water quality environmental monitoring, electronics design and development, oceanographic research, energy, medical imaging and pharmaceutical research.
    $113.6k-151.4k yearly 60d+ ago
  • R&D Scientist

    Kalon Executive Search

    Associate scientist job in San Diego, CA

    Job Description Our client, a fast-growing leader in the functional food, supplement, and wellness ingredient industry, is seeking an accomplished R&D Scientist to drive innovation and scientific excellence across their ingredient portfolio. This individual will play a critical role in developing, optimizing, and validating ingredient processes and analytical methods to advance the potency, consistency, and bioavailability of natural, bioactive compounds. This position is ideal for a technically driven and entrepreneurial scientist who thrives in a collaborative environment, excels at translating scientific insights into commercial outcomes, and is passionate about functional nutrition and wellness innovation. The R&D Scientist will lead research and development initiatives focused on ingredient optimization, analytical method development, and bioactive compound testing. Partnering closely with cross-functional teams-including Quality, Mycology, and Operations-this individual will support the full lifecycle of ingredient innovation, from discovery through commercialization. The successful candidate will be hands-on, organized, and capable of managing multiple complex projects simultaneously, while fostering a culture of scientific curiosity, precision, and accountability. **This is a hybrid position must onsite at least 3 days a week in San Diego, CA. Key Responsibilities Develop and optimize analytical and testing methods to support ingredient characterization and functional performance. Design and validate finished product specifications related to nutritional and bioactive properties. Partner with external laboratories and contract research organizations to conduct analytical testing and ensure data quality. Drive new ingredient development projects, including feasibility assessments, process optimization, and product qualification. Collaborate cross-functionally to ensure projects meet technical, regulatory, and commercial readiness milestones. Provide scientific input and data to support patent filings and intellectual property development. Support investigations related to food safety, quality, and testing accuracy in partnership with internal QA/FSQA teams. Contribute scientific insights and innovative concepts that expand the R&D and innovation pipeline. Qualifications Master's degree (M.Sc.) or higher in Chemistry, Biochemistry, Food Science, or a related scientific field. 5+ years of experience in R&D, product development, or analytical science within the functional ingredients, dietary supplement, or food industry. Experience with analytical methods such as mass spectrometry, chromatography, DNA sequencing, or immunoassays is strongly preferred. Proven experience collaborating with external laboratories or CROs. Strong technical writing, data interpretation, and presentation skills. Ability to manage multiple complex projects in a fast-paced, dynamic environment. Creative, detail-oriented, and motivated by scientific discovery and product excellence. This is an exciting opportunity to join a mission-driven organization at the forefront of functional ingredient innovation-combining science, sustainability, and wellness to shape the next generation of food and nutrition solutions. If you are an experienced R&D scientist seeking to make a meaningful impact in a rapidly growing segment of the health and wellness industry, we'd love to connect with you. Compensation: $120,000 - $140,000plus benefits If this sounds like the position you have been waiting for, please apply using the online application or the link below - all inquiries are strictly confidential. Our focus is to assist you to make your best next career move, and we will not use your information for any other purpose. Kalon Search is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. *******************
    $120k-140k yearly 5d ago
  • Associate Scientist I, Discovery Chemistry (Bioconjugation)

    Arrowhead Pharmaceuticals 4.6company rating

    Associate scientist job in San Diego, CA

    Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position Arrowhead is seeking a highly motivated Associate Scientist to join our growing Discovery Chemistry team at our San Diego site. This individual will primarily focus on oligonucleotide bioconjugation, peptide synthesis, purification, and analytical chemistry. As a discovery chemist, you will play a key role in the development and optimization of si RNA-based therapeutics by applying your expertise in bioconjugation strategies and peptide chemistry. Responsibilities Maintain a well-documented laboratory notebook Track progress against project timelines, generate regular status updates, and communicate progress and issues to management Perform tasks across projects Manage time effectively to meet deadlines Adhere to safe laboratory practices Prioritize and perform synthesis, purification, and analysis of conjugates based on project deliverable timelines Requirements: B.S. or M.S. Chemistry or Biochemistry degree with excellent understanding of organic and analytical chemistry 0-3 years of experience working in a chemistry laboratory Experience with a wide range of analytical techniques, especially HPLC Ability to quickly learn new procedures and techniques Preferred: Experience working with large-molecule synthetic targets, particularly oligonucleotides, in an academic or industry setting Experience with solid-phase peptide synthesis (automated and/or manual) Prior experience in a pharmaceutical or biotechnology environment California pay range $60,000-$80,000 USD Arrowhead provides competitive salaries and an excellent benefit package. All applicants must have authorization to work in the US for a company. California Applicant Privacy Policy
    $60k-80k yearly Auto-Apply 4d ago
  • Manufacturing Scientist

    Universal Sequencing Technology Corporation

    Associate scientist job in Carlsbad, CA

    Universal Sequencing Technology, a biotech startup headquartered in Canton, MA (~15 miles southwest of Boston) with a location in Carlsbad, CA, is looking for a highly talented Manufacturing Scientist to join the team, located in Carlsbad, CA.* We are excited to provide novel DNA sequencing technology for the Next Generation Sequencing (NGS) platforms that enables many previously unachievable applications. This position is a unique opportunity to commercialize a novel NGS library technology, TELL-Seq TM , an ultra-low input single tube linked read technology which enables many previously unachievable long read applications and to develop disruptive single cell applications. The incumbent will have hands on experience on DNA conjugation and amplification, in-process quality control assay development, filling and labeling experience and capability to increase scalability using technology, equipment, manpower, etc… to meet increasing demand. S/He will work closely with R&D and manufacturing teams to scale up production procedure and accelerate product commercialization. S/He must have excellent documentation skills and strong interpersonal skills, be driven by making high quality products, and enjoy working in a multi-disciplinary environment. Key Responsibilities Engineer scale up procedures for bulk production, filling process and kit assembly Optimize reagent formulation and process for bulk DNA amplification in emulsions Develop in-process quality control assays (analytical) for reagent formulations, productions, characterization and identification Execute well thought out experiments, record results accurately along with in-depth analysis and reports that will be reviewed, approved and filed in QA Create/update manufacturing production protocols, execute protocol and/or train others to do the same Work with other manufacturing personnel to make bulks, fill reagents and assemble kits. This is a hands on, in the lab position Work with Inventory Management to ensure proper handling, storage, usage and accountability of all materials needed to produce or test products Manage and execute stability sampling, storage and testing Manage tasks, projects and timeline to meet deliverable on time and on quality. Manage resources accordingly for the same Write, review and revise SOP's through a Document Change Order. Initiates, Investigates and write up non-conformance reports. Required Skills and Background M.Sc. or Ph.D. in chemistry, chemical engineering, molecular biology, biochemistry, biology, biotechnology or a similar field (B.S. with exceptional experience WILL be considered) Prior GMP and GDP experience is required. Hands on experience with magnetic beads (suspension material), oligo conjugation and quantification Direct experience in nucleic acid amplification technologies, particularly in emulsion PCR Experience in Lean Six Sigma project implementation is a plus 5-7 years experience in a reagent GMP environment Detail oriented and very good documentation skill Hands on leaders perform well in this environment
    $79k-118k yearly est. Auto-Apply 60d+ ago
  • Scientist, Protein Production and Characterization

    Alivamab Discovery Services

    Associate scientist job in San Diego, CA

    Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: * Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems * Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required * Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics * Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets * Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems * Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making * Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: * Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required * Proven hands-on experience with multiple mammalian expression platforms is required * Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required * Experience with therapeutic antibody developability assessment is highly desirable * Strong analytical, troubleshooting, and communication skills with exceptional attention to detail * Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI
    $98.5k-140k yearly Auto-Apply 60d+ ago
  • Scientist, Protein Production and Characterization

    Director, Business Development In San Diego, California

    Associate scientist job in San Diego, CA

    Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI
    $98.5k-140k yearly Auto-Apply 60d+ ago
  • Scientist, Protein Production and Characterization

    Deerfield Management Companies 4.4company rating

    Associate scientist job in San Diego, CA

    Scientist, Protein Production and Characterization AlivaMab Biologics is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab Mouse suite of transgenic mice. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science. We are seeking a highly motivated and skilled Scientist to join our Protein Sciences team and contribute to both day-to-day operations and the advancement of Protein Science workflows. This position will focus on the design, optimization, and execution of transient transfection processes at various scales for antibody and protein production in mammalian expression systems. The successful candidate will leverage expertise in biophysical characterization and biochemical modification to evaluate key protein attributes. This position will report to the Associate Director of Protein Sciences and work closely with scientists in the Antibody Discovery, Antibody Engineering, Protein Sciences, and Project Management teams. The ideal candidate will drive innovation through process refinement, high-throughput automation, and growing proficiency of chemical conjugation techniques. This role offers the opportunity to work in a fast-paced, collaborative research environment, where creative solutions and a strong scientific approach are key to success. Responsibilities Responsibilities: Independently design, plan, and execute transient transfection workflows for antibody and protein production across various mammalian expression systems Develop, design, and optimize protein purification methods to enhance throughput, quality, and efficiency, as required Lead developability assessment studies by designing and conducting analytical experiments to evaluate protein stability, purity, and key biophysical characteristics Support production of complex construct design strategies (e.g VLPs, nanodiscs etc.), to enable immunization antibody discovery campaigns against challenging targets Drive implementation of automated high throughput processes to support protein production workflows using Bravo, and other robotic systems Maintain meticulous experimental records using electronic notebook (Benchling), and communicate results clearly through written reports and presentations to support project progression and scientific decision-making Contribute innovative ideas and collaborate effectively across teams to foster research excellence and ensure project success in a fast-paced environment Qualifications Qualifications: Ph.D. in Biochemistry, Chemistry, Molecular Biology, Protein Engineering, or a related field with a minimum of 2 years of industry experience or MS with minimum of 6 years of direct industry experience is required Proven hands-on experience with multiple mammalian expression platforms is required Proficiency with AKTA instrumentation, and a broad range of purification techniques, including affinity chromatography, ion exchange, HIC, and SEC, as well as standard protein QC methodologies is required Experience with therapeutic antibody developability assessment is highly desirable Strong analytical, troubleshooting, and communication skills with exceptional attention to detail Motivated self-starter with excellent organization, teamwork, and a passion for scientific innovation About AlivaMab Biologics AlivaMab Biologics sets its partners' antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, AMB delivers drug-quality, fully human antibodies on exceptional timelines. AMB achieves its partners' design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. AMB focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The AMB team's experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab Mouse platforms, ensure the highest probability of success. The salary range for this position considers various factors, including skills, experience, training, certifications, and organizational needs. Note that this range does not reflect any geographic adjustments based on the location where the role will be based. At AlivaMab Biologics, it is uncommon for a new hire to start at or near the top of the salary range, as compensation is tailored to each individual's skills and breadth and depth of experience. The current estimated range is $98,500 - $140,000, plus a bonus target, benefits, and equity. AlivaMab Biologics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. #LI-DNI
    $98.5k-140k yearly Auto-Apply 60d+ ago
  • Research Biologist

    Global Channel Management

    Associate scientist job in San Diego, CA

    Research Biologist needs 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Research Biologist requires: Bachelors degree in biology, biochemistry, molecular biology or similar discipline with 1 or more years of research experience in an academic institute, biotechnology or pharmaceutical industry Experience in running biochemical and immunological assays. Highly motivated and agile biochemist Research Biologist duties: Perform experiments to characterize protein-protein interactions using PAGE, Western Blot, ELISA & SPR technologies Perform basic tasks to support tissue culture and maintenance of immune competent cell lines Perform basic cell-based assays with immunology research-related technologies (e.g. human whole blood, primary human leukocyte isolation, cellular activation and differentiation, FACS, cytokine assay, etc.) Work with a cross-disciplinary team for data analysis Independently execute experiments, analyze, interpret and present experimental data
    $61k-93k yearly est. 60d+ ago
  • Research Associate I - Sati Lab - Department of Neurology

    Cedars-Sinai 4.8company rating

    Associate scientist job in San Diego, CA

    Are you a hardworking and dedicated research professional interested in being part of breakthrough Research? When you join Cedars-Sinai, you become part of a team that is at the forefront of medical advancements and life-saving medical and scientific breakthroughs. Cedars-Sinai is one of the leading institutes for driven research funding from the National Institutes of Health. Principal Investigator, Pascal Sati, PhD is searching for a Research Associate I to join the team! The Sati Laboratory focuses on the development of novel imaging biomarkers, magnetic resonance imaging (MRI) techniques, and artificial intelligence (AI) methods that strive to improve the clinical care offered to those impacted by neurological disorders. To learn more, please visit the Sati Research Lab. Working under direct supervision, the Research Associate I performs a variety of computational procedures to support the objectives of the laboratory research projects in Neuroimaging. Assists in laboratory activities, including maintenance of imaging pipelines and computer equipment. Keeps accurate and detailed records of imaging dataset, pipelines and results. The incumbent will be able to perform routine image processing and analysis of neuroimaging dataset. This position does not have supervisory responsibilities. Primary Duties and Responsibilities: Performs a variety of routine laboratory tasks and procedures related to Neuroimaging. Assists in the operation of specialized computing equipment. Performs lab maintenance duties, including data backup and software upgrades. Assists students and fellows at the laboratory. Maintains lab computer equipment and related records. Observes and aligns with safety standards and procedures. Department-Specific Duties: Performs image processing, image segmentation and image analysis of neuroimaging dataset. Implements and optimizes image processing algorithms used in neuroimaging research. Qualifications Education: Bachelor's degree in a Science related field, required. Experience and Skills: Research laboratory experience is preferred. Understanding of general research objectives. Solid understanding of programming languages, neuroimaging tools, computing environments, database management, personal and server computers, and statistical platforms. Experience with routine imaging processing procedures for neuroimaging research. Must possess digital literacy to include, but not limited to, Unix/Linux systems, Python, Matlab, Bash, R, REDCap, SPSS and Excel. About UsCedars-Sinai is a leader in providing high-quality healthcare encompassing primary care, specialized medicine and research. Since 1902, Cedars-Sinai has evolved to meet the needs of one of the most diverse regions in the nation, setting standards in quality and innovative patient care, research, teaching and community service. Today, Cedars- Sinai is known for its national leadership in transforming healthcare for the benefit of patients. Cedars-Sinai impacts the future of healthcare by developing new approaches to treatment and educating tomorrow's health professionals. Additionally, Cedars-Sinai demonstrates a commitment to the community through programs that improve the health of its most vulnerable residents. About the TeamCedars-Sinai is one of the largest nonprofit academic medical centers in the U.S., with 886 licensed beds, 2,100 physicians, 2,800 nurses and thousands of other healthcare professionals and staff. Choose this if you want to work in a fast-paced environment that offers the highest level of care to people in the Los Angeles that need our care the most. Req ID : 13460 Working Title : Research Associate I - Sati Lab - Department of Neurology Department : Neurology Business Entity : Cedars-Sinai Medical Center Job Category : Academic / Research Job Specialty : Research Studies/ Clin Trial Overtime Status : NONEXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $24 - $29.87
    $24-29.9 hourly 23h ago
  • Molecular and Cell Biology Principal Research Scientist, Targeted Drug Delivery

    Califesciences

    Associate scientist job in San Diego, CA

    Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has approved medicines that treat the underlying causes of multiple chronic, life‑shortening genetic diseases - cystic fibrosis, pain, sickle cell disease and transfusion‑dependent beta thalassemia - and continues to advance clinical and research programs in these diseases. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases. Principal Research Scientist The Principal Research Scientist will focus on targeted drug delivery including nucleic acid therapies. This role will be on‑site in our state‑of‑the‑art research site in San Diego. The successful candidate will have extensive expertise in receptor biology and targeted delivery in extrahepatic tissues/cells which is instrumental in the development of novel therapeutics. Key Duties and Responsibilities Develop and implement strategic plans for receptor & ligand identification, characterization, optimization, and application in drug discovery. Responsible for executing research plans, collecting and interpreting data, trouble shooting, and defining next steps. Collaborate with cross‑functional partners (medicinal chemistry, computational genomics, molecular and cellular biology, pharmacology, protein sciences) to support integrated drug discovery programs from target validation through lead optimization. Apply innovative approaches and stay current with advances in receptor biology, ligand discovery, and nucleic acid therapeutics to strengthen pipeline opportunities. Prepare and present data in project team meetings, contributing scientific insight and recommendations to guide program strategy. Maintain high standards of scientific rigor, accurate documentation, data integrity, and compliance with regulatory guidelines. Knowledge and Skills Strong expertise in receptor biology, ligand‑receptor interactions and signaling mechanisms. Hands‑on experience with biochemical, biophysical, and/or cell‑based assays to study receptor function and behavior. Experience with ligand‑mediated delivery into specific tissues or cell types is highly desirable. Demonstrated track record of scientific achievement (e.g., publications, presentations, or contributions to therapeutic programs) in receptor biology and targeted drug delivery. Ability to collaborate effectively within multidisciplinary project teams. Excellent personal and communication skills, with the ability to influence stakeholders and drive decision‑making across functions. Proven ability to thrive in a fast‑paced, multidisciplinary, and innovative environment. Education and Experience Ph.D. (or equivalent degree) in biology, biochemistry or related science and 4-7 years of relevant post‑doctoral employment experience, or Master's degree (or equivalent degree) in biology, biochemistry or related science and 7+ years of relevant employment experience, or Bachelor's Degree (or equivalent degree) in biology, biochemistry or related science and 10+ years of relevant employment experience. Pay Range $136,000 - $204,000 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job‑related factors permitted by law. Benefits At Vertex, our Total Rewards offerings also include inclusive market‑leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week‑long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation On‑Site Designated Flex Eligibility Status In this On‑Site designated role, you will work five days per week on‑site with ad‑hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. Company Information Vertex is a global biotechnology company that invests in scientific innovation. Equal Employment Opportunity Statement Vertex is committed to equal employment opportunity and non‑discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E‑Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com. #J-18808-Ljbffr
    $136k-204k yearly 5d ago
  • Lead Scientist, In Vitro Antibody Discovery

    Eli Lilly and Company 4.6company rating

    Associate scientist job in San Diego, CA

    A global healthcare leader in San Diego seeks a highly motivated scientist to contribute to the discovery and development of biotherapeutics. The role involves discovering and optimizing antibodies, utilizing flow cytometry, and requires strong skills in molecular biology and biochemistry. Ideal candidates should have significant industry experience and be detail-oriented, with excellent communication skills. Competitive compensation and benefits include a flexible benefits package and bonus potential. #J-18808-Ljbffr
    $120k-159k yearly est. 6d ago

Learn more about associate scientist jobs

How much does an associate scientist earn in Bonita, CA?

The average associate scientist in Bonita, CA earns between $62,000 and $153,000 annually. This compares to the national average associate scientist range of $53,000 to $109,000.

Average associate scientist salary in Bonita, CA

$98,000
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