Associate scientist jobs in Pawtucket, RI - 1,066 jobs

Our commitment to people with neuromuscular diseases Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more ************************* and follow us on X, LinkedIn and Facebook. Role Summary: The Principal S cientist , ADME-PK in Preclinical Development (PCD) department utilize s their knowledge in drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamic and bioanalytical principles to advance Dyne 's efforts surrounding delivery of therapeutic payloads to muscle and CNS tissues with the FORCE platform . This role is based in Waltham, MA. Primary Responsibilities Include: Design and execute internal/external preclinical studies to understand the pharmacokinetics (PK) and absorption, metabolism, distribution, and excretion (ADME) of Dyne's drug candidates Represent PCD as the ADME-PK subject matter expert on discovery and program teams Partner with and support Research, Toxicology, Translational Biomarkers, Clinical, Regulatory, Project Management and other Dyne departments Collaborate with Clinical Pharmacology/Pharmacometrics to develop quantitative tools to translate PK/PD relationship from preclinical to clinical Author high quality Regulatory documents including INDs, CTAs, and NDA/BLA filings. Prepare strategic and science-based ADME strategies that meet regulatory requirements and program goals Facilitate strategic scientific communication via meetings, abstracts and manuscripts Education and Skill Requirements: PhD in Pharmacokinetics, Pharmacology, Pharmaceutics, Biomedical Sciences or other relevant field with >6 years (MS with >8 years, BS with >12 years) of experience in the biopharmaceutical industry, with evidence of drug development experience Strong knowledge of drug metabolism, ADME concepts, pharmacokinetics, pharmacodynamics and bioanalytical principles F amiliarity with regulatory submission including FIH dosing strategy is highly desirable Proficient in using WinNonlin or other pharmacokinetic software Excellent communication (verbal and written) and presentation skills, as well as interpersonal skills and the ability to represent PCD in a team environment Experience with PK characterization of protein therapeutics or antibody-drug conjugates (ADCs) is desired #LI-Onsite MA Pay Range $159,000 - $195,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. #J-18808-Ljbffr

A leading healthcare institution in Boston seeks a Sr. Principal Scientist to oversee operations in a GMP lab, focusing on the production and quality control of radiopharmaceuticals. The ideal candidate will have extensive experience in aseptic operations, knowledge of QC methodologies, and a strong educational background in pharmaceuticals. This role requires meticulous documentation, adherence to GMP standards, and the ability to thrive in a fast-paced environment, contributing to pioneering advancements in patient care. #J-18808-Ljbffr

A leading biotechnology company is seeking a Principal ML Scientist to innovate in drug discovery using machine learning techniques. This role involves conducting advanced research and providing technical leadership in the application of foundation models for drug discovery. Ideal candidates will possess a Ph.D. in a relevant field, have a strong publication record, and experience in programming with languages like Python and C++. The company offers competitive compensation and relocation benefits. #J-18808-Ljbffr

Qubit Pharmaceuticals is a French-American deeptech startup, focusing on discovering novel molecules for complex targets in healthcare and materials science. We leverage proprietary molecular simulation and quantum-physics based modeling technology to develop our own discovery programs that we either co-develop with or license out to pharmaceutical and industrial partners. This enables us to design more effective and safer drug candidates, aiming to significantly reduce the time and investment needed for discovery. In just 18 months, Qubit Pharmaceuticals grew its portfolio to 7 programs in oncology, immunology & antivirals. Our cutting-edge technology is based on over 30 years of research by our academic founders, and relies on three main components: in-depth expertise in computational science and high-performance computing (HPC), quantum chemistry and artificial intelligence algorithms, and a powerful, automated cloud platform for molecular simulation with chemical accuracy. We recently announced the launch of the world's most powerful AI foundation model for molecular simulation. Qubit Pharmaceuticals is looking for an Senior Machine Learning and Quantum Chemistry Scientist to lead the development of foundation models for chemistry. The perfect fit for this job At Qubit Pharmaceuticals, we are looking for a Senior Machine Learning and Quantum Chemistry Scientist who is quick at adapting to new challenges and issues. This person will be eager to learn, meet the needs of users, and work in a collaborative process with teammates and across multiple teams. Your role As a member of the Research team, you will be responsible for the Quantum Chemistry Foundation Model development, including molecules quantum datasets selection, model training, coding, testing and validation. Develop new methods to solve practical and challenging problems in Machine Learning and Quantum Chemistry applied to chemistry & drug discovery Communicate the results of your research by filing patent applications, publishing peer-reviewed papers and giving presentations at research conferences Provide technical support to users Your qualifications and skills Master degree or equivalent in Applied Maths / Computer Science / Chemistry PhD in Quantum Chemistry and Machine learning is strongly preferred Minimum of 5 years work experience (including PhD) is required Knowledge of quantum chemistry is strongly preferred Proficiency in active learning, architecture, and training methods, related to Machine Learning Force Field, Machine Learning Interaction Potentials, Neural Networks Potentials Ability to motivate and lead a project team Excellent communication skills for explaining complex concepts to non-specialists Agility in a startup environment (changing priorities, multiple projects) Open-source code development and maintenance is valuable The proposal benefits & perks Duration: Full time - Permanent Starting from October 2025 Salary according to profile Health insurance and provident fund 100% covered Lunch vouchers worth €9 covered at 50%. Location: Paris 14th arrondissement / Boston Possibility of remote work for 2 days per week. #J-18808-Ljbffr

Join Axon and be a Force for Good. At Axon, we're on a mission to Protect Life. We're explorers, pursuing society's most critical safety and justice issues with our ecosystem of devices and cloud software. Like our products, we work better together. We connect with candor and care, seeking out diverse perspectives from our customers, communities and each other. Life at Axon is fast-paced, challenging and meaningful. Here, you'll take ownership and drive real change. Constantly grow as you work hard for a mission that matters at a company where you matter. Your Impact We are seeking highly skilled and innovative Computer Vision and Machine Learning Scientist to join our AI team, focusing on AI applications in Cloud, Devices and Robotics. As a key member of our research and development efforts, you will play a crucial role in advancing the state-of-the-art in Multimodal Large Language Models (MLLMs), Computer Vision technologies for our cloud, devices and robotics. You will collaborate with cross-functional teams to design, develop, and deploy cutting-edge computer vision algorithms and solutions that enable intelligent perception and understanding of visual data. What You'll Do Location: Hybrid in Seattle OR Remotely from the US Reports to: Senior Manager, Research Science Own one or more key technical areas across CVML product portfolio. Provide technical leadership to junior scientists, guiding the transition of R&D concepts into impactful CVML product feature. Research and develop cutting-edge techniques in MLLMs, GenAI, and Computer Vision across cloud, devices and sensors based data sources. Design and implement efficient and scalable MLLM models for inference and analysis of visual data. Explore novel approaches to address challenges in object detection, recognition, tracking, segmentation, and scene understanding. Optimize algorithms for performance, memory footprint, and energy efficiency to meet the requirements of resource-constrained devices. Join forces with MLEs or firmware or hardware engineers to leverage hardware accelerators and optimize algorithms for specific hardware architectures. Evaluate the performance of MLLM models using real-world datasets and design experiments to validate their effectiveness. Stay up-to-date with the latest research trends and advancements in computer vision, machine learning, and deep learning, MLLMs, GenAI and integrate relevant findings into our projects. Contribute to patent disclosures, academic publications, and technical documentation to share insights and findings with the broader community. Experience coach and mentor junior scientists. What You Bring PhD and with +8 year experience in Computer Science or a related field with a focus on MLLMs, computer vision, machine learning, or artificial intelligence. Proven track record of research excellence in machine learning, computer vision, robotics perception, demonstrated through publications in top-tier conferences or journals. Strong proficiency in programming languages such as Python, C/C++, experience with deep learning frameworks such as TensorFlow, PyTorch, or Keras and experience with ROS or robotic operational system. Drive one or more phases of the ML development lifecycle: shape datasets, investigate modeling approaches and architectures, train/evaluate/tune models and implement the end-to-end training pipeline. Leverage state-of-the-art research to deliver high quality models enabling multiple AI projects at scale. Contribute back to the research community via academic publications, tech blogs, open-source code and contributing to internal/external AI challenges Experience in developing computer vision algorithms for resource-constrained devices such as mobile phones, IoT devices, or embedded systems is highly desirable. Excellent problem-solving skills, analytical thinking, and the ability to work autonomously as well as collaboratively in a team environment. Well-developed communication skills and the ability to effectively present complex technical concepts to both technical and non-technical audiences. Benefits that Benefit You Competitive salary and 401k with employer match Discretionary paid time off Paid parental leave for all Medical, Dental, Vision plans Fitness Programs Emotional & Mental Wellness support Learning & Development programs And yes, we have snacks in our offices Benefits listed herein may vary depending on the nature of your employment and the location where you work The Pay: Axon is a total compensation company, meaning compensation is made up of base pay, bonus, and stock awards. The starting base pay for this role is between USD 181,000 in the lowest geographic market and USD 266,000 in the highest geographic market.The actual base pay is dependent upon many factors, such as: level, function, training, transferable skills, work experience, business needs, geographic market, and often a combination of all these factors. Our benefits offer an array of options to help support you physically, financially and emotionally through the big milestones and in your everyday life. To see more details on our benefits offerings please visit ****************************** Don't meet every single requirement? That's ok. At Axon, we Aim Far. We think big with a long-term view because we want to reinvent the world to be a safer, better place. We are also committed to building diverse teams that reflect the communities we serve. Studies have shown that women and people of color are less likely to apply to jobs unless they check every box in the . If you're excited about this role and our mission to Protect Life but your experience doesn't align perfectly with every qualification listed here, we encourage you to apply anyways. You may be just the right candidate for this or other roles. Important Notes The above is not intended as, nor should it be construed as, exhaustive of all duties, responsibilities, skills, efforts, or working conditions associated with this job. The job description may change or be supplemented at any time in accordance with business needs and conditions. Some roles may also require legal eligibility to work in a firearms environment. Axon's mission is to Protect Life and is committed to the well-being and safety of its employees as well as Axon's impact on the environment. All Axon employees must be aware of and committed to the appropriate environmental, health, and safety regulations, policies, and procedures. Axon employees are empowered to report safety concerns as they arise and activities potentially impacting the environment. We are an equal opportunity employer that promotes justice, advances equity, values diversity and fosters inclusion. We're committed to hiring the best talent - regardless of race, creed, color, ancestry, religion, sex (including pregnancy), national origin, sexual orientation, age, citizenship status, marital status, disability, gender identity, genetic information, veteran status, or any other characteristic protected by applicable laws, regulations and ordinances - and empowering all of our employees so they can do their best work. If you have a disability or special need that requires assistance or accommodation during the application or the recruiting process, please ***************************. Please note that this email address is for accommodation purposes only. Axon will not respond to inquiries for other purposes. #J-18808-Ljbffr

PRIDE Health is seeking a travel Cath Lab Technologist Senior for a travel job in framingham, Massachusetts. Job Description & Requirements Specialty: Cath Lab Technologist Discipline: Allied Health Professional Start Date: 01/19/2026 Duration: 13 weeks 40 hours per week Shift: 8 hours, days Employment Type: Travel Title: Cath Lab Tech Location: Framingham, MA Duration: 13 weeks Shift: 5x8 Days Schedule:40 hours Hourly Pay Rate: $75.25-$77.25 Qualifications & Experience required RCIS certification (Registered Cardiovascular Invasive Specialist) - core credential. 1-2 years of experience working in a cardiac catheterization lab environment. Associate degree in cardiovascular technology or a related field is commonly required or strongly preferred. Basic Life Support (BLS) certification; Advanced Cardiac Life Support (ACLS) is preferred. Roles & Responsibilities Prepare patients for cardiac catheterization procedures Set up and maintain sterile equipment and cath lab instruments Assist cardiologists during procedures like angiograms and stent placements Operate imaging and monitoring equipment (fluoroscopy, ECG, BP monitors) Monitor patient vital signs throughout the procedure Ensure patient safety and follow radiation & infection control guidelines Document procedure details accurately Clean, restock, and prepare the cath lab for the next case Work closely with doctors, nurses, and the cath lab team Benefits: Pride Global offers eligible employee's comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, auto, home insurance, pet insurance, and employee discounts with preferred vendors. About: Pride Health is the minority-owned healthcare recruitment division of Pride Global, an integrated human capital solutions and advisory firm. With our robust and abundant travel nursing and allied health employment options across the U.S., PRIDE Health will allow you to help change the way the world lives and heals as it connects you with the industry's leading healthcare organizations. About PRIDE Health PRIDE Health is the minority-owned healthcare recruitment division of Pride Global-an integrated human capital solutions and advisory firm. With our robust and abundant travel nursing and allied health employment options across the U.S., PRIDE Health will allow you to help change the way the world lives and heals as it connects you with the industry's leading healthcare organizations. Pride Global offers eligible employee's comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, auto, home insurance, pet insurance, and employee discounts with preferred vendors. Benefits Weekly pay Holiday Pay Guaranteed Hours 401k retirement plan Cancelation protection Referral bonus Medical benefits Dental benefits Vision benefits

Applied Physical Sciences (APS) is looking for a highly motivated Physical Scientist to join the Concord, MA team in a part-time, on-call (PTOC) position. Successful candidates will have a PhD in theoretical physics, expertise in inverse theory or tomography, and will support the development of state-of-the-art technologies for tomographic imaging with irregular experiment apertures, with a special emphasis on exploitation of high energy X-rays. APS works on exciting, technically challenging, cutting-edge technologies that will expose candidates to a wide variety of multidisciplinary fields, providing a stimulating environment with considerable opportunity for collegial interaction. At APS you will work in a small company environment where technical excellence is rewarded and an entrepreneurial spirit is encouraged, and you will have the chance to work directly with colleagues and customers that value innovation and creativity. Responsibilities Theoretical modeling of x-ray interaction physics, development of X-ray inversion paradigms for highly challenging experiment scenarios, rigorous characterization of the fundamental information limits of X-ray imaging. Software implementation of processing and modeling techniques, numerical execution of synthetic inversion experiments, display and quantification of model uncertainty Required Attributes and Skills PhD in theoretical physics, and expertise in modeling and inversion of X-ray data Subject matter expertise in one or more of the following: advanced numerical optimization, statistical methods, experiment design optimization, GPU-based computing Extensive experience with computational methods and programming for modeling physical phenomena and processing of real data e.g., Matlab, Python, PyTorch, or Fortran Exceptional communication skills (written and oral) for technical documentation and reviews with customers Desired Attributes and Skills Professional experience of 10+ years in DoD or related industry, a strong publication history in refereed technical journals, and a track record of successful performance on research programs under DARPA, IARPA, NAVSEA or ONR sponsorship is preferred. Experience as principal investigator working on advanced R&D programs Demonstrated technical leadership in modeling and simulation Expertise in one or more of the following: mathematical physics, model-based iterative methods for x-ray tomography, Monte Carlo radiative transport methods for Bremsstrahlung modeling, advanced numerical optimization techniques involving both continuous and discrete variables, regularization methods, uncertainty quantification using the Fisher Information Matrix and the Cramer-Rao Bound, and multi-objective optimization. Experience presenting talks at technical conferences APS, a wholly owned subsidiary of the General Dynamics Corporation, offers a small company environment including competitive salary, excellent benefits, and comfortable working conditions. This is a part-time on-call position open in the Concord, MA office. Candidates must possess or be able to obtain a Top Secret DOD security clearance. Qualified applicants are invited to submit a resume and application online at **************** fax them to ************, Attn: Human Resources, or mail to the company address. Please reference the requisition number and title of the position in the subject line of your submission. Equal Opportunity Employer/M/F/Disability/Protected Vet Invitation to Self-Identify In keeping with our commitment to Equal Employment Opportunity (EEO), Applied Physical Sciences invites all applicants to self-identify pre-offer as a protected veteran and/or an individual with a disability. Invitation to Self-Identify as Protected Veteran Online Form Invitation to Voluntary Self-Identification of Disability Online Form #J-18808-Ljbffr

+++ SiPhox Health is redefining clinical immunoassay diagnostics by miniaturizing the analytical power of a central lab into an accessible, affordable, at-home platform. Our silicon-photonics architecture unites advanced biochemistry, microfluidics, and semiconductor-grade manufacturing to deliver precise, multiplexed biomarker quantification in minutes on a device the size of a coffee maker. We are building what we believe will become the first mass-market photonic blood analyzer, enabling continuous improvement in chronic disease management through frequent, high-quality testing. +++ The Opportunity +++ We are looking for a Senior Assay Development Scientist or Engineer who wants to build assays that have never been built on this kind of platform before. If you thrive on developing rigorous, quantitative immunoassays, including challenging free/competitive assays, and want your work to directly ship in a consumer device used by millions, this is one of the rarest opportunities in diagnostics today. This role sits at the center of platform innovation, contributing directly to analytical chemistry, surface chemistry, microfluidics, and silicon photonics integration. You will shape a growing assay menu that spans hormones, inflammatory markers, metabolic proteins, and future pediatric/specialty panels. +++ What You'll Do +++ Core Assay Development Develop quantitative sandwich and competitive immunoassays (including free hormone assays, displacement-driven formats, and low-abundance biomarkers) on a silicon-photonic resonance platform. Design, execute, and interpret experiments focused on: Binding kinetics & equilibrium optimization Surface functionalization strategies Competitive assay dynamic-range shaping Calibrator and control development (matrix selection, commutability) Assay precision, stability, robustness Analytical Performance & Validation Own assay verification and validation aligned with CLSI standards (EP05, EP06, EP07, EP09, EP10, EP17). Establish and demonstrate performance for: Analytical sensitivity & functional limit (LoB/LoD/LoQ) Linearity & reportable range (including hook effects, competitive assay inflection characterization) Repeatability, reproducibility, and nested CV analysis Interference and cross-reactivity studies Matrix equivalency & recovery studies Build calibration models for a novel platform (e.g., 4PL/5PL, competitive curve inversion, chip-specific normalization frameworks). Cross-Functional Integration Collaborate deeply with photonics, microfluidics, reader electronics, manufacturing, and product engineering teams to close the loop on real-world assay performance. Work with process development and chemistry groups to scale assays from prototype to production, enabling high-volume, chip-based manufacturing. Documentation & Execution Deliver high-clarity technical reports, protocols, V&V documentation, and design-history file content that meets IVD and FDA expectations. Present results across the company to inform design decisions and product milestones. +++ What We're Looking For +++ Technical Background PhD + 2 years, or MS + 6 years in biochemistry, chemical engineering, analytical chemistry, biophysics, bioengineering, or related fields. Expertise in immunoassay development (sandwich and competitive). Experience with free hormone assays is a major plus. Demonstrated ability to independently solve complex analytical and biochemical problems. Hands-on experience with complex analytical workflows, assay automation, and instrumentation. Strong understanding of calibration design, commutability, and control strategies. Familiarity with statistical analysis of assay performance, including mixed-model ANOVA, CV decomposition, and method-comparison frameworks. Regulatory & Platform Experience (Bonus) Experience with IVD development, ISO 13485, or 21 CFR 820. Experience with POC or novel-platform assay development. Knowledge of label-free sensors, waveguides, or photonic resonance systems. Experience with Python, R, or MATLAB for data analysis, curve fitting, and automation. Personal Traits Strong scientific intuition paired with rigorous data discipline. Thrives in a fast-paced, milestone-driven startup environment. Creative problem solver willing to challenge established assay paradigms. High integrity, willingness to own outcomes, and a collaborative mindset. +++ Why This Role Is Unique +++ Most assay developers spend their careers optimizing assays on platforms that already exist. At SiPhox, you will: Build the first generation of photonic immunoassays deployed in consumer health. Design assays whose constraints are shaped by semiconductor physics as much as biochemistry. Work on hard problems (free hormone assays, multiplexing, competitive equilibrium, small-volume matrices) where innovation, not incrementalism, wins. See your work ship in a product used at home by real people, not just research labs. If you want to work at the frontier of diagnostics (where photonics, biochemistry, and consumer health converge) we'd love to meet you.

6-month Contract Onsite- Lexington, MA Must be able to work on a W2 The Formulation Scientist will support pharmaceutical research activities with a focus on the formulation and characterization of peptides, proteins, small molecules, and bioconjugates. This is an individual contributor role reporting into pharmaceutical formulation sciences and working closely with internal project teams and research colleagues. Requirements Prepare peptide and protein injectable formulations for in vitro and in vivo studies, including selection of buffers, excipients, and surfactants Conduct biophysical characterization and stability studies for injectable formulations Support injectable formulation preparation for animal studies Collaborate with cross-functional teams to ensure dosage forms meet desired biophysical and biochemical profiles Contribute to early screening strategies and execution Operate, maintain, and troubleshoot biophysical and analytical laboratory instrumentation Perform laboratory work in a safe and efficient manner to maintain a safe working environment Communicate effectively and address technical challenges as they arise Qualifications Bachelor's degree required; background in biological, biochemical, or pharmacological sciences preferred Minimum of 2 years of relevant technical experience Strong expertise in injectable formulation development and biophysical characterization Experience with spectroscopy, calorimetry, light scattering, and other biophysical methods preferred Proficiency in data analysis, interpretation, and scientific problem solving Experience managing projects and working collaboratively across functional teams Strong scientific communication skills High attention to detail and ability to document experimental work using ELN systems General knowledge of cGMP, GLP, and pharmaceutical regulatory requirements preferred

About the job: SciPro is partnered with a fast growing Scientific Data and AI platform startup who is searching for a Senior Applied AI/ML Engineer to join their team. They are catalyzing the Scientific AI revolution by designing and industrializing AI-native scientific data across the scientific value chain and scientific vertices. They bring this AI data to life in a fast growing suite of universal lab data management solutions, scientific use cases, and AI-based scientific outcomes. Requirements: You will be a critical team member in a unique partnership to industrialize Scientific AI. As such, you will engage directly with customers onsite up to 4-5 days per week in the Boston region. Advanced degree in Biological, Data, or Computer Science Portfolio demonstrating end-to-end ownership of AI/ML products Proven track record of deploying AI models addressing real world problems Experience in biotech, biopharma, or pharma-adjacent projects Superior talent developing at least one of: ML-Reinforcement Learning, LLM/NLP, or Protein Design/Diffusion Models Responsibilities: Responsible for designing, developing, training, and validation of AI/ML products Support and advise executive leadership regarding technical and commercial feasibility Work with commercial teams to understand the impact of AI in life-sciences Collaborate with cross functional teams to build products Preferred Qualifications: Deep understanding of hurdles facing pharmaceutical drug development Demonstrated ability to make productized applications (for use by more than one group) Excellent communication skills Ability to advocate and evangelize for AI initiatives internally and externally Experience collaborating with teams on large software projects

Vaxess is developing a pipeline of next-generation therapeutics on our novel micro-array patch platform. With only five minutes of wear-time on the skin, the Vaxess' patch combines room temperature stability with simplified application to dramatically alter the way that drugs are delivered. Vaxess is committed to enabling products that are not only more effective, but also more accessible to patients around the world. The Role We are seeking a motivated and detail-oriented Research Associate with strong hands-on experience in chromatographic analysis to support QC release and stability testing. The successful candidate will perform routine cGMP QC testing using HPLC methods (RP-HPLC, SEC, IEX), Agilent HPLC systems, and additional supporting assays in a fast-paced, collaborative environment. This is a unique opportunity to be part of an emerging early-phase clinical company bringing innovative technology to the global market. Key Responsibilities Perform routine QC release and stability testing using HPLC methods including RP-HPLC, SEC, and IEX. Prepare samples, operate Agilent HPLC systems, verify system suitability, and ensure analyses meet method and specification requirements. Execute complementary analytical assays such as UV-Vis, pH, surface tension, and mechanical tests. Maintain complete, accurate documentation in compliance with cGMP, ALCOA+, and data integrity requirements. Conduct routine instrument care (solvent flushes, column care, daily checks) and assist troubleshooting under supervision. Process and review chromatographic data in Agilent OpenLab CDS. Support method qualification, validation, and transfer activities by executing protocols and recording observations. Maintain calibration, maintenance, and service records for analytical instrumentation. Independently author method SOPs, analytical protocols, technical reports, and contribute to regulatory submissions. Collaborate cross-functionally with QC, Analytical Development, Process Development, Manufacturing, and Regulatory teams to enable program success. Maintain rigorous laboratory documentation and complete, audit-ready analytical records. Thrive in a fast-paced, cross-functional environment with excellent communication and organizational skills. Qualifications Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or related field with 1-3 years of experience; or a master's degree with relevant laboratory experience. Hands-on experience operating HPLC systems; Agilent systems and OpenLab CDS experience strongly preferred. Practical experience with chromatographic techniques including RP-HPLC, SEC, and IEX. Experience supporting QC release or stability testing in a GMP/GLP environment. Strong attention to detail and ability to follow SOPs precisely. Excellent documentation practices and understanding of data integrity. Strong organizational skills with the ability to manage multiple workflows and prioritize effectively in a fast-paced environment. Excellent verbal and written communication skills and comfort working within interdisciplinary teams. Commitment to collaborative work within interdisciplinary project teams. At Vaxess, we're bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. To apply, please submit your CV/resume to ****************** .

A prominent pharmaceutical company is seeking a Translational PET Imaging Scientist to lead clinical implementation of novel PET tracers in oncology studies. Responsibilities include developing imaging strategies, overseeing studies, and managing regulatory submissions. The ideal candidate should hold a Ph.D. and have extensive experience in advancing PET tracers into clinical trials with proven project leadership. This role offers a hybrid work model and a competitive salary range. #J-18808-Ljbffr

Prepare injectable (parenteral) peptide and protein formulations to support in vivo and in vitro animal studies, including buffer, excipient, and surfactant selection Execute preclinical formulation development activities to support early research and screening programs Perform biophysical characterization and stability studies to assess formulation performance and robustness Support animal dosing studies by preparing, documenting, and delivering study-ready formulations Maintain accurate experimental records using ELN (Electronic Laboratory Notebook) and manage formulation requests/workflows Operate, maintain, and troubleshoot formulation, biophysical, and analytical laboratory instruments Analyze experimental data and contribute to scientific documentation and reporting Collaborate closely with cross-functional research teams to resolve formulation challenges and meet project timelines

Job Title: Research Associate/Sr. Research Associate, Discovery Biology/Drug Discovery Institute: Institute of Organic Chemistry and Biochemistry (IOCB) Boston Position Type: Full-Time, In-Person / Laboratory-Based (no remote work) Classification: Exempt -- This position is classified as exempt and involves advanced professional duties requiring specialized knowledge in a scientific field. About the Position The Institute of Organic Chemistry and Biochemistry (IOCB) is expanding its presence in the Boston area and is seeking a Research Associate or Associate Scientist to join our Drug Discovery team. This role offers a unique opportunity to contribute to both hypothesis-driven basic research and early pre-clinical drug discovery efforts. The ideal candidate is highly hands-on and intellectually curious, with strong experience in cell biology, molecular biology, and biochemistry, and an interest in building robust assays and generating high-quality data to support target validation and drug discovery. Key Responsibilities Experimental Design & Execution Under the guidance of the Head of Drug Discovery, independently plan and execute experiments, analyze data, and clearly communicate results in team meetings and to external collaborators. Maintain rigorous documentation and reproducibility standards (e.g., controls, repeatability, robust assay performance). Collaborative Drug Discovery Research Partner closely with interdisciplinary colleagues (proteomics, protein science, computational, external academic collaborators) to advance target validation, mechanism-of-action studies, and early discovery programs. Contribute to project planning, experimental prioritization, and interpretation of results in a drug-discovery context. Assay & Method Development Develop, optimize, and validate cellular and biochemical assays (e.g., potency, selectivity, pathway readouts). Support screening workflows and follow-up characterization of hits. Leverage and/or help expand capabilities in discovery biology, proteomics, biophysics, and protein science as needed. Required Qualifications Education & Experience Research Associate: Bachelor's degree with relevant research experience Sr. Research Associate: Master's degree with relevant research experience Core Competencies Strong hands-on experimental ability in one or more of: cell biology, molecular biology, biochemistry, biophysics Self-directed, organized, and motivated; able to work effectively both independently and in a collaborative team environment Strong written and verbal communication skills with attention to detail and data integrity Technical Expertise (or Strong Willingness to Learn) Drug Discovery Biology: biochemical and/or cell-based assay development; screening support; basic screening data analysis; data organization and tracking Molecular Biology: cloning, mutagenesis, PCR/Gibson, RT-qPCR, Western blotting; experience with CRISPR/Cas9 a plus Software & Data: proficiency with GraphPad Prism and Microsoft Office (Word/Excel/PowerPoint); familiarity with Python for data analysis is a plus Preferred Qualifications Prior experience in an academic or industry drug discovery environment (target validation, assay development, screening, hit follow-up) Experience working with compound libraries and follow-up screening logistics Demonstrated interest in translational science and using modern tools/technologies to answer biological questions Salary Range: Research Associate $69,000 - 71,000 USD per year, Sr. Research Associate $75,000 - 90,000 USD per year. The salary range listed represents IOCB Boston's good faith estimate for this position and is based on factors including, but not limited to, education, experience, skills, internal equity, and market data. Final compensation will be commensurate with qualifications and experience. Benefits: Competitive benefits package including employer-subsidized medical, dental, and vision insurance; transportation contribution; generous paid time off; and company-paid Accidental Death & Dismemberment (AD&D), Short-Term Disability (STD), Long-Term Disability (LTD), and life insurance. Work Authorization/Visa Sponsorship: IOCB Boston does not sponsor employment-based visas for this position. Candidates must be legally authorized to work in the United States at the time of hire and must maintain work authorization throughout the duration of employment without the need for current or future employer sponsorship. Employment eligibility will be verified in accordance with federal law. IOCB Boston participates in the federal E-Verify program. Employment offers are contingent upon the successful completion of a background check conducted in accordance with applicable federal and Massachusetts laws Why Join Us You'll join a collaborative and ambitious team working at the interface of basic biology and early drug discovery. This role provides meaningful ownership of experiments and methods, opportunities to work across disciplines, and the chance to contribute to high-impact science in a fast-moving, supportive environment. TO APPLY: Please email ********************************* to express your interest. Include your most recent curriculum vitae or resume as well as a cover letter that describes your interest in this position. Direct applicants only. IOCB Boston does not accept unsolicited resumes from recruitment or employment agencies. Equal Employment Opportunity Statement IOCB Boston is an Equal Opportunity/Affirmative Action Employer. We are committed to providing equal employment opportunities to all qualified applicants and employees without regard to race, color, religion, sex, sexual orientation, gender identity or expression, age, national origin, disability, protected veteran status, genetic information, or any other status protected by applicable law.

A prestigious research institution in Boston is seeking an Associate in Biomedical Informatics to support biomedical research training and projects. The role involves developing knowledge graphs, conducting data analyses, and writing research reports under the guidance of experienced mentors. Applicants should have a Bachelor's degree in computer science and a keen interest in healthcare technologies. #J-18808-Ljbffr

Job Title: Senior Scientist / Associate Principal Scientist, Chemical Engineering R&D FLSA Status: Exempt Salary: $100,000-$160,0000 Pharmaron is a global CRO helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services. We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules to biologics and gene therapies, and we work with more than 3,000 global customers. To learn more, visit ****************** About the Role The Pharmaron Process Chemistry department is seeking highly motivated Chemical Engineers for an exciting role involving hands-on small-molecule process development and scale-up from laboratory to commercial manufacturing. Engineers in this position will design, plan, and implement both chemistry laboratory and in-silico experiments to support process and technology development for active pharmaceutical ingredients (APIs). This position will combine elements of chemistry, engineering, technology development, and data analysis to optimize manufacturing processes. Strong teamwork, innovation, creativity, and organizational skills are essential, along with clear and confident communication to address technical challenges. Effective collaboration across multidisciplinary teams in the US, UK, and China, is critical, and a strong commitment to safety, quality compliance, and technical leadership is expected throughout all activities. Key Responsibilities Perform hands-on small molecule process development and scale-up work. Use Design of Experiments (DoE) for process screening, optimization, and robustness studies. Define CPPs, PARs, NORs, and contribute to the development of scalable control strategies. Apply process analytical technology (PAT) and process modeling. Evaluate and model kinetics, mixing, mass/heat transfer, and reactor performance. Conduct independent research to achieve mechanistic understanding for rational process design. Design and optimize key unit operations including crystallization, filtration, drying, distillation, and extraction. Use process modeling tools to inform scale-up strategies. Translate lab-scale findings into actionable parameters for kilo lab and GMP manufacturing. Drive cycle time reduction and process intensification initiatives. Implement innovative technologies such as continuous flow chemistry and automation platforms. Support internal and external tech transfer activities, including scale-up studies, modeling, and verification experiments. Support development of complex transformations such as catalytic hydrogenation. Exhibit a mindset of safety and quality compliance. Collaborate cross-functionally within US, UK, and China-based teams. Required Experience & Skills Education Minimum Requirement: The position requires either a BS and/or MS in Chemical Engineering (or comparable) from an accredited college/university plus at least 5 years of relevant work experience in small-molecule chemical process development - OR - a PhD in Chemical Engineering (or comparable) from an accredited college/university with at least 2 years of relevant work experience post PhD defense. Experience performing lab-based research/process development in a chemical engineering-related area. Experience with organic chemical synthesis and wet chemistry. Experience with small molecule pharmaceutical drug substance development. Experience applying statistical experimental design (i.e. Design of Experiments) and/or process modeling. A high level of innovation, creativity, and self-initiative. Highly effective communication and collaboration skills. Good organizational, interpersonal, writing, and time management skills. Preferred Experience & Skills Experience with process scale-up and/or technology transfer, moving from laboratory to pilot plant or production scale. Familiarity with concepts and application of cGMP and GDP during pharmaceutical development and production. Demonstrated experience with chemical engineering-related technology development. Familiarity with kilo-scale laboratory equipment. Experience with process modeling (e.g., population balance modeling, distillation modeling). Knowledge with milling equipment (spiral jet mills, pin mills, co-mills, rotor-stator wet mills). Why Pharmaron? Collaborative Culture: Thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners and collaborators. Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package: Insurance including Medical, Dental & Vision with significant employer contributions Employer-funded Health Reimbursement Account Healthcare & Dependent Care Flexible Spending Accounts 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance 401k plan with generous employer match Access to an Employee Assistance Program How to Apply: Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today! Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China. As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

MST Process Engineer/Scientist III, Downstream - PLA JOB SUMMARY/OBJECTIVE: The primary responsibility is to participate in Manufacturing Sciences and Technology activities in support of downstream technology transfer, late stage clinical, PPQ and commercial manufacturing of viral vectors. The individual will serve as a process expert in downstream processing. This position requires close interaction with MS&T colleagues, Project Management, Manufacturing, Quality Assurance, Quality Control, Process Development, Engineering, Supply Chain, and other departments. This role will focus on aspects of implementing manufacturing processes to produce early- and late-phase human clinical trial and commercial gene therapy products. RESPONSIBILITIES: MST process lead for Downstream technology transfer activities involved in manufacturing viral vectors following cGMP guidelines. Collaborate with other sites or clients to ensure success of process transfer and scale up. Ensure effective information flow, risk assessment, timeline execution, issue resolution and documentation for multi-departmental teams (Process Development, Manufacturing, Quality, and Project Management). Includes authoring detailed process definition, facility fit, and raw material risk assessments. Author PPQ protocols and reports. Oversee execution of PPQ and PPQ related activities Develop sampling plans with clients and incorporate them into cGMP batch documentation. Monitor and trend process performance, including input and output parameters. Find opportunities to improve systems and practices KNOWLEDGE, SKILLS and QUALIFICATIONS: A degree in biochemical engineering, chemical engineering or related scientific field such as molecular biology, virology, biochemistry. Advanced degree preferred. B.S. with 8+ years, Master's degree with 6+ years, or PhD with 3+ years' professional history. Technical expertise in downstream biopharmaceutical manufacturing and/or process development. Experience with automated chromatography systems (AKTA) and automated tangential flow filtration (Repligen). Expertise in late stage/commercial technology transfer, process characterization and process validation biopharmaceutical/gene transfer vector manufacturing preferred. Knowledge of GMP and regulatory requirements of biopharmaceutical manufacturing, specifically cell and gene therapy vector production Ability to work both independently and as part of a team. Proficiency in operating effectively in a fast-paced dynamic environment while juggling multiple projects Project management skills desirable Ability to speak effectively before groups of customers. Excellent investigational skills and ability to solve technical issues. Ability to compile, analyze and interpret data; Ability to write routine reports and correspondence. Strong interpersonal skills to facilitate verbal and written communication. Excellent Benefits Benefits & Total Rewards | Thermo Fisher Scientific Medical, Dental, & Vision benefits-effective Day 1 Paid Time Off & Designated Paid Holidays Retirement Savings Plan Tuition Reimbursement OTHER Relocation assistance is not provided. Must be legally authorized to work in the United States now and in the future, without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening Compensation and Benefits The salary range estimated for this position based in Massachusetts is $83,300.00-$125,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: A choice of national medical and dental plans, and a national vision plan, including health incentive programs Employee assistance and family support programs, including commuter benefits and tuition reimbursement At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: *****************************************************

Spear Bio, founded in 2021, is a well-funded and rapidly growing biotech start-up headquartered in Woburn, Massachusetts. Our proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), is a novel wash-free immunoassay platform, offering unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring by providing scalable, ultrasensitive solutions that deliver unparalleled accuracy in measuring low-abundant biomarkers, enabling clinicians and researchers to improve patient outcomes and advance global health. Research Associate/Associate Scientist: We are seeking a highly motivated and experienced Research Associate/Associate Scientist to join our growing Assay Development team, with hands-on experience running ultrasensitive immunoassays and the desire to be at the forefront of innovative research. This individual will play a pivotal role in advancing Spear Bio's new range of ultrasensitive immunoassays and assay biomarker programs. This role is based onsite in our lab in Woburn, MA 5 days/wk. Responsibilities: Test and execute immunoassay workflows on high-throughput, semi-automated platforms Assist in optimizing methods for processing different types of biofluid samples (ie. serum, plasma) for assay development Set up, calibrate, and maintain laboratory equipment, as specified by the requirements of various projects Assist in data analysis Acquire necessary equipment and supplies for various projects Qualifications: Master's degree in Biology, Biochemistry, Biophysics, Biomedical Engineering or a related discipline plus 1-3 years of assay development experience in an industry or academic lab Direct experience running biofluid-based immunoassays and qPCR experimentation is required Experience with neurodegenerative disease protein biomarkers a plus (ie. pTau217, pTau181, NFL, GFAP, alpha-synuclein, etc.) Experience characterizing and troubleshooting immunoassays Strong proficiency in molecular biology lab techniques General Qualifications: Self-motivated and ability to perform complex tasks in an effective manner Ability to follow instructions and grow in a mentorship setting Excellent organizational and documentation skills Desire to learn and implement new technologies Strong presentation and interpersonal skills, ability to build collaborative working relationships, and become a key contributor within the assay development team Work 5 days/week on site in Woburn, MA. LOCAL CANDIDATES will be given priority consideration for this position. We offer competitive compensation, meaningful stock ownership, comprehensive benefits, and a great work environment. This is an opportunity to enter an innovative, high-growth startup at an early stage and play an integral role in the company's growth and success. We are focused on identifying candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of building an industry-leading company. Spear Bio Inc. provides equal opportunity in employment to all persons. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability. Spear Bio does not accept resume submissions from external recruiting agencies. Any unsolicited resumes or candidate information submitted without prior written agreement will be deemed the property of Spear Bio, and no placement fees will be paid.

Piper Health & Sciences is seeking a full-time iPSC Production Scientist to join a growing organization's Bio/Engineering Production team onsite at their Massachusetts location. The ideal candidate will have a strong biology background and hands-on experience in iPSC stem cell culture, differentiation, and QC within a pharmaceutical or biotech environment. Responsibilities of the iPSC Production Scientist Include: * Full-time onsite schedule: Monday-Friday, 9:00 AM - 5:00 PM * Lead and support iPSC production and related lab activities * Perform hands-on stem cell culture and differentiation * Execute QC-related tasks in accordance with SOPs * Maintain accurate lab documentation and records * Support Bio/Engineering Production workflows * Follow all safety, GMP, and GLP standards Qualifications of the iPSC Production Scientist Include: * Biology degree is strongly preferred (Biomedical Engineering degrees are NOT a fit) * Proven hands-on experience with: * iPSC cell culture * Stem cell differentiation * Quality Control (QC) processes * Pharmaceutical or biotech industry experience preferred Compensation of the iPSC Production Scientist Includes: * Salary Range: $83,200.00 - $114,000.00 per year (equivalent to $40.00 - $55.00 per hour), based on experience and certifications. * Comprehensive Benefits: CIGNA Medical, Dental, Vision; 401k through ADP and sick leave as required by law. * Ability to work with a well renowned and growing organization that has a robust pipeline and quality culture. This job opens for applications on 1/12/2026. Applications for this job will be accepted for at least 30 days from the posting date. #LI-AW1 #LI-ONSITE keywords: Scientist, iPSC Production, stem cell culture, induced pluripotent stem cells, cell differentiation, quality control, QC, laboratory scientist, cell biology, biotechnology, pharmaceutical production, bioengineering, GMP, GLP, SOP compliance, tissue engineering, regenerative medicine, bioprocessing, cell therapy, stem cell research, lab operations, onsite scientist, Medford MA jobs, contract scientist, PhD biology, master's biology, postdoctoral research, biotech scientist, pharma scientist, cell culture specialist, stem cell specialist, iPSC scientist, QC scientist, bio production scientist, laboratory techniques, cell-based assays, biotech careers, pharma careers, stem cell manufacturing, cell culture workflows, life sciences jobs, biopharma jobs, laboratory compliance, scientific documentation, biotech industry experience, pharmaceutical industry experience, cell line development, research scientist, production scientist, laboratory QC, stem cell differentiation protocols, cell culture maintenance, full-time onsite scientist, bioengineering production team, regenerative biology, tissue culture, cell therapy manufacturing, biotechnology research, pharmaceutical QC, biomanufacturing, cell biology techniques, stem cell QC testing, scientific method, laboratory safety standards, GMP compliance, GLP compliance, biotech contract role, scientist contract position, iPSC culturing, stem cell production, biotech Medford MA, pharma Medford MA, scientific careers, laboratory scientist jobs, cell therapy scientist, bioprocess scientist, QC laboratory scientist, stem cell lab work, biotech production workflows, pharmaceutical production workflows, life sciences contract jobs, biotech contract scientist, pharma contract scientist.