Associate scientist jobs in West Memphis, AR - 43 jobs

The Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results. The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. At St. Jude Children's Research Hospital, talented faculty and staff work together and with colleagues worldwide to advance the research and treatment of pediatric cancer and other catastrophic diseases. We are seeking an outstanding, highly motivated, and creative Scientist to join Dr. Jonathan Yen's lab and the Therapeutic Genome Engineering (TGEn) group. You will be part of a multidisciplinary team of scientists and clinical researchers helping to advance genome editing strategies for treating sickle cell disease to a Phase 1 clinical trial. Our ongoing therapeutic pipeline is fueled by internal scientific discoveries directed from “bench-to-bedside” and academic collaborations. Come join TGEn to en GENEer concepts to cures! You will have the opportunity to work with a talented interdisciplinary team of scientists to develop a cellular therapy with the goal of treating patients here at St. Jude Children's Research Hospital and worldwide. The ideal candidate will have a strong combination of experience with genome editing and human hematopoietic stem cells (HSCs). You will also have the opportunity to learn about and support new, exciting projects, including the development and optimization of pre-clinical genome editing strategies to treat hemoglobinopathies and other hematological diseases, process development, and IND-enabling studies (Pharm/Tox). Job Responsibilities: Perform studies to develop genome editing strategies for human hematopoietic stem cells (HSC). Design and execute IND-enabling experiments to characterize the pharmacology of a genome-edited human hematopoietic stem cell product to treat sickle cell disease. Characterize the efficacy, safety, and potency of the HSC cellular drug product in in vitro and xenotransplantation assays. Multicolor flow cytometry and FACS to sort hematopoietic populations of relevance. Develop experimental methods including RT-PCR, dd PCR, next-generation sequencing, and single-cell sequencing. Perform NGS library preparation and analysis of editing outcomes, on-target and off-target. Evaluate scale-up and close-system processes to ensure reproducibility of the drug product. Conduct exploratory research on developing novel in-vitro and in-vivo delivery strategies. Interact and collaborate with multidisciplinary teams to advance the program. Establish tracking and trending analyses of process development and pilot runs. Draft documentation (protocols, batch records, reports) to standardize and transfer process to GMP facility. Maintains regular and predictable attendance. Performs other related duties as assigned to meet the goals of the department and institution. Minimum Education and/or Training: Bachelor's degree in a relevant scientific area is required. Master's or PhD degree in a relevant scientific area is highly preferred. Associate Scientist Minimum Experience: 7 + years of research experience is required 5 + years of research experience is required with a Master's degree 2 + years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel preferred Proven performance in earlier role/comparable role Salary range: $65,520.00 - $114,400.00 Scientist Minimum Experience: Eight (8) years of relevant post-degree work experience is required with a Bachelor's degree. Six (6) years of relevant post-degree work experience is required with a Master's degree. Three (3) years of relevant post-degree work experience is required with a PhD. Experience leading and supporting research experiments preferred. Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred. Experience in guiding and training other laboratory personnel preferred. Proven performance in earlier role/comparable role. Salary range: $86,320.00 - $154,960.00 Welcome to Memphis This position is based in Memphis, TN; relocation assistance is available. Memphis is a family-friendly metropolitan area that more than a million residents call home. Memphis is recognized for its world-class music, food, and hospitality. Cost of living is one of our biggest attractions; in fact, Money listed Memphis as one of the least expensive cities in which to raise a child. Mild winters and beautiful green spaces make the city a magnet for outdoor enthusiasts - there are over 200 miles of bike-friendly lanes with more being added. Forbes recently named Memphis the 4th happiest city in which to work. Apply today! A cover letter is highly recommended. Interested applicants should submit a cover letter as part of the application process. Please address your cover letter to: Jonathan Yen, PhD Department of Hematology Mail Stop 355 St. Jude Children's Research Hospital 262 Danny Thomas Place Memphis, TN 38105-3678 Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Associate Scientist or Scientist - Yen Lab/Therapeutic Genome Engineering (TGEn Group). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Our client is a public and rapidly growing diagnostics company that is looking to expand their Quality team in Memphis TN. They are willing to assist with relocation. Relocation assistance is provided! Excellent benefits, competitive salary, and stock options. Job Description Under direct supervision, responsible for design, performance and interpretation of experiments in support of the company's product development. Responsibilities: Responsible for the design and conduct of experiments as defined by work streams in accordance with the company's Quality System and to regulatory standards Ensures that work is completed to agreed timelines, communicating delays or issues to supervisor in timely manner Prioritizes workload to insure key objectives are met on time May supervise the work of a junior member of staff Presents data at internal and external meetings Ensures that conclusions in written reports reflect the data presented and reports are of the highest quality When required, operate as a scientist in support of running Laboratories, ensuring that the Quality Management System, including ISO 9001:2008, ISO 13485:2003, CLIA and CAP, is adhered to at all times and in all aspects of the job Perform other duties in departments on an occasional basis to meet critical company objectives Follows all company safety policies & other safety precautions within work area Regular attendance and timeliness is essential Qualifications BS or MS Degree in life sciences, Higher preferred Experience with cell culture techniques imperative Hands-on experience with flow cytometry and PCR techniques Demonstrated understanding of the diagnostic and pharmaceutical industries Familiarity with Quality System concepts and requirements including GMP and ISO Working knowledge of ELISA and ELISPOT a distinct advantage Expert at analyzing data Must be proficient in MS Office Additional InformationAll your information will be kept confidential according to EEO guidelines.

**Meet the Team** Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. **Your Impact** + Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. + Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. + Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. + Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. + Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. **Minimum Qualifications:** + PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. + Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. + Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) + Experience translating research ideas into production systems. **Preferred Qualifications:** + Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. + Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. + Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. + Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. + Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. + MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. + Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. **Why Cisco?** At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. **Message to applicants applying to work in the U.S. and/or Canada:** The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: + 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees + 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco + Non-exempt employees** receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees + Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) + 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next + Additional paid time away may be requested to deal with critical or emergency issues for family members + Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: + .75% of incentive target for each 1% of revenue attainment up to 50% of quota; + 1.5% of incentive target for each 1% of attainment between 50% and 75%; + 1% of incentive target for each 1% of attainment between 75% and 100%; and + Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. ** Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements. Cisco is an Affirmative Action and Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, national origin, genetic information, age, disability, veteran status, or any other legally protected basis. Cisco will consider for employment, on a case by case basis, qualified applicants with arrest and conviction records.

The University of Tennessee Health Science Center is seeking a Postdoctoral Scholar to work in Pediatrics Infectious Disease. This position develops and analyzes mathematical models of the immune response to viral and bacterial infections and coinfections. This lab is a dual dry/wet laboratory and uniquely generates robust data sets to train and validate model predictions. EDUCATION: Ph.D. in Mathematics, Computer Science, Physics, Engineering, or a related field. KNOWLEDGE, SKILLS, AND ABILITIES: Skill in viral and bacterial infection and immune response modeling. Demonstrated ability to conduct interdisciplinary research in these areas. Skill in model development, including formulation, implementation, and validation of computational approaches. Knowledge of parameter estimation techniques and skill in applying data-driven modeling methods to complex biological data. Proficient programming skills in Matlab and/or Python, with the ability to write efficient, well-documented code. Excellent oral and written communication skills, with the ability to present research clearly to scientific and non-scientific audiences. Ability to work independently, as well as collaboratively in a team. Skill in mentoring and providing guidance to graduate students, technicians, or undergraduate researchers. WORK SCHEDULE: This position may frequently be required to work weekends and evenings. May require occasional overnight travel. Designs, implements, and analyzes novel dynamical mathematical and computational models. Prepares manuscripts for peer-reviewed journals and contributes to grant proposals. Utilizes models to generate new hypotheses and help design new experiments. Develop independent research skills and career trajectory. Collaborate with other lab members, faculty, staff, and external colleagues on research projects. Presents findings at lab meetings, seminars, and conferences. Maintains accurate records and ensures reproducibility of results. Assists with progress reports and manages research resources responsibly. Provides technical guidance and mentorship to students.

NEW Senior Medical Technologist/MLT opening in the Memphis, Tennessee area for permanent, direct hire! This client is actively interviewing on all shifts! Job Details: -Full time, permanent MT/MLT opening -Full, comprehensive benefits package (PTO, health insurance, life insurance, 401k, etc) -All shifts open (you can choose!) -Lots of room for opportunity and career growth -LARGE sign on bonuses! Job Requirements: -ASCP (MLT/MT/MLS) certification or eligibility (need to obtain within 6 months of hire) -Experience in the laboratory is preferred -Minimum Associate Degree in Science Interested in hearing more? Apply now or send a resume to marissak@ka-recruiting.com for consideration/questions. (Reference Code: MK285)

The Scientist performs and/or coordinates a wide range of laboratory research procedures and conducts a spectrum of complex support tasks and projects determined by the field and scope of the particular research study. Also, performs a variety of laboratory techniques independently and presents results. The Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. St. Jude Children's Research Hospital is seeking a talented and motivated Associate Scientist or Scientist to join the clinical assay development team in Molecular Pathology. This bench-focused role, ideal for early-career researchers, will contribute to the advancement of innovative assays for future clinical applications. Our current priorities include developing assays that leverage long-read sequencing platforms and emerging methylation detection technologies. Strongly Desired Qualifications and Skills: Strong background in genomics, molecular biology, or a related field. Hands-on experience with different next-generation sequencing platforms. Ability to work effectively in a collaborative, multidisciplinary environment. Excellent communication skills and attention to detail. Experience with long-read sequencing and methylation detection would be a plus. Clinical laboratory training and experience with CAP-compliant documentation would be a plus. Experience with automation platforms would be a plus. Key Responsibilities: Contribute to the development and optimization of novel molecular assays for clinical implementation. Conduct pre-validation and validation wet-lab experiments with minimal supervision. Ensure high standards of data accuracy and reliability. Collaborate with bioinformatics scientists and pathologists to ensure analysis and interpretation of complex genomic data. Author and maintain SOPs and validation documentation in compliance with CAP regulations. Train laboratory staff on newly developed assays. Present research findings at internal and external conferences. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Scientist Minimum Experience: Eight (8) years of relevant work experience is required Six (6) years of relevant work experience is required with a Master's degree Three (3) years of relevant work experience is required with a PhD Salary range: $86,320.00 - $154,960.00 Associate Scientist Minimum Experience: 7 + years of research experience is required 5 + years of research experience is required with a Master's degree 2 + years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel preferred Proven performance in earlier role/comparable role Salary range: $65,520.00 - $114,400.00 Position is primarily onsite in Memphis, TN. Schedule Monday-Friday 8 a.m. to 4:30 p.m. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Associate Scientist or Scientist - Molecular Pathology. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Meet the Team Splunk, a Cisco company, is building a safer, more resilient digital world with an end‑to‑end, full‑stack platform designed for hybrid, multi‑cloud environments. Join the Foundational Modeling team at Splunk, where we advance the state of AI for high‑volume, real‑time, multi‑modal machine‑generated data - including logs, time series, traces, and events. We combine deep AI research expertise with the scale and operational excellence of Splunk and Cisco's global engineering capabilities. Our work spans networking, security, observability, and customer experience - designing and deploying foundation models that enhance reliability, strengthen security, prevent downtime, and deliver predictive insights across Splunk Observability, Security, and Platform at enterprise scale. You'll be part of a culture that values technical excellence, impact‑driven innovation, and cross‑functional collaboration - all within a flexible, growth‑oriented environment. Your Impact * Lead the research, design, and deployment of large‑scale foundation models for machine‑generated data - primarily time series, augmented with logs traces, and events. * Optimize distributed training and inference pipelines to maximize accuracy, performance, and efficiency at scale. * Work closely with engineering, product, and data science to ensure solutions meet defined technical requirements and deliver tangible business impact. * Mentor team members and contribute directly to model architecture reviews, experimental design, and production rollout processes. * Stay current with AI/ML developments and integrate relevant advancements into ongoing projects and technical plans. Minimum Qualifications: * PhD in Computer Science, or related quantitative field, plus 1+ years of industry research experience. * Proven track record in at least one of the following areas: large language modeling for both structure and unstructured data, deep learning‑based time series modeling, advanced anomaly detection, and multi-modality modeling. * Solid proficiency in Python and deep learning frameworks (e.g., PyTorch, TensorFlow) * Experience translating research ideas into production systems. Preferred Qualifications: * Deep Learning for Time Series & Forecasting - Proven expertise designing and deploying architectures such as temporal transformers, temporal convolutional networks, and spatial‑temporal models. * Advanced Anomaly Detection - Experience creating robust, scalable approaches (statistical, deep learning, or hybrid) for high‑volume, real‑time time series data. * Multi‑Modal AI Modeling - Strong track record fusing logs, time series, traces, tabular data, and graphs for foundation models tackling complex operational insights. * Probabilistic Forecasting & Uncertainty Quantification - Skills in Bayesian deep learning and probabilistic models to capture and communicate predictive uncertainty. * Large‑Scale Training & Optimization - Experience optimizing model architectures, distributed training pipelines, and inference efficiency to minimize cost and latency while preserving accuracy. * MLOps & Continuous Learning - Fluency in automated retraining, drift detection, incremental updates, and production monitoring of ML models. * Strong Research Track Record - Publications in top AI/ML conferences or journals (e.g., NeurIPS, ICML, ICLR, AAAI, CVPR, ACL, KDD) demonstrating contributions to state‑of‑the‑art methods and real‑world applications. Why Cisco? At Cisco, we're revolutionizing how data and infrastructure connect and protect organizations in the AI era - and beyond. We've been innovating fearlessly for 40 years to create solutions that power how humans and technology work together across the physical and digital worlds. These solutions provide customers with unparalleled security, visibility, and insights across the entire digital footprint. Fueled by the depth and breadth of our technology, we experiment and create meaningful solutions. Add to that our worldwide network of doers and experts, and you'll see that the opportunities to grow and build are limitless. We work as a team, collaborating with empathy to make really big things happen on a global scale. Because our solutions are everywhere, our impact is everywhere. We are Cisco, and our power starts with you. Message to applicants applying to work in the U.S. and/or Canada: The starting salary range posted for this position is $174,500.00 to $226,500.00 and reflects the projected salary range for new hires in this position in U.S. and/or Canada locations, not including incentive compensation*, equity, or benefits. Individual pay is determined by the candidate's hiring location, market conditions, job-related skillset, experience, qualifications, education, certifications, and/or training. The full salary range for certain locations is listed below. For locations not listed below, the recruiter can share more details about compensation for the role in your location during the hiring process. U.S. employees are offered benefits, subject to Cisco's plan eligibility rules, which include medical, dental and vision insurance, a 401(k) plan with a Cisco matching contribution, paid parental leave, short and long-term disability coverage, and basic life insurance. Please see the Cisco careers site to discover more benefits and perks. Employees may be eligible to receive grants of Cisco restricted stock units, which vest following continued employment with Cisco for defined periods of time. U.S. employees are eligible for paid time away as described below, subject to Cisco's policies: * 10 paid holidays per full calendar year, plus 1 floating holiday for non-exempt employees * 1 paid day off for employee's birthday, paid year-end holiday shutdown, and 4 paid days off for personal wellness determined by Cisco * Non-exempt employees receive 16 days of paid vacation time per full calendar year, accrued at rate of 4.92 hours per pay period for full-time employees * Exempt employees participate in Cisco's flexible vacation time off program, which has no defined limit on how much vacation time eligible employees may use (subject to availability and some business limitations) * 80 hours of sick time off provided on hire date and each January 1st thereafter, and up to 80 hours of unused sick time carried forward from one calendar year to the next * Additional paid time away may be requested to deal with critical or emergency issues for family members * Optional 10 paid days per full calendar year to volunteer For non-sales roles, employees are also eligible to earn annual bonuses subject to Cisco's policies. Employees on sales plans earn performance-based incentive pay on top of their base salary, which is split between quota and non-quota components, subject to the applicable Cisco plan. For quota-based incentive pay, Cisco typically pays as follows: * .75% of incentive target for each 1% of revenue attainment up to 50% of quota; * 1.5% of incentive target for each 1% of attainment between 50% and 75%; * 1% of incentive target for each 1% of attainment between 75% and 100%; and * Once performance exceeds 100% attainment, incentive rates are at or above 1% for each 1% of attainment with no cap on incentive compensation. For non-quota-based sales performance elements such as strategic sales objectives, Cisco may pay 0% up to 125% of target. Cisco sales plans do not have a minimum threshold of performance for sales incentive compensation to be paid. The applicable full salary ranges for this position, by specific state, are listed below: New York City Metro Area: $199,700.00 - $292,800.00 Non-Metro New York state & Washington state: $174,500.00 - $260,500.00 * For quota-based sales roles on Cisco's sales plan, the ranges provided in this posting include base pay and sales target incentive compensation combined. Employees in Illinois, whether exempt or non-exempt, will participate in a unique time off program to meet local requirements.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description They must have protein purification experience including non-labeled proteins and They are NOT looking for candidates with molecular/PCR/gene cloning, etc. Summary Description: Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. Duties: o Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). o Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. o Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. o Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. o Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. o Train Production Technicians in upstream and downstream manufacturing processes. o Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. o Write and execute validation protocols for new and existing manufacturing processes. o Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications Required Qualifications: o Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. o Extensive knowledge and hands on experience of protein purification and characterization. o Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. o Hands on experience with in vitro cell culture and recombinant protein fermentation o Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. o Proven experience with process scale-up procedures. o Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). o Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. Requirements (Physical, Mental, Environmental Demands): o Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. o Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. o Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. o Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. o Must be able to lift up to 30lbs. multiple times daily. o Must be able to travel by air/car to other locations of MBI as needed. o May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Manisha Jathar 732 429 1850

The Postdoctoral Scholar investigates the novel functions of autism spectrum disorder-associated genes in the blood-brain barrier. EDUCATION: Ph.D. in Neuroscience or a related field. KNOWLEDGE, SKILLS, AND ABILITIES: Skill in gene cloning, proteomics, confocal imaging, brain surgery, brain Ca2+ imaging in vivo, behavioral testing, brain histology, and computational/statistical analyses. Ability to work independently, self-motivated and detail oriented. WORK SCHEDULE: This position may occasionally be required to work weekends and evenings. Performs mouse brain surgery, in vivo Ca2+ imaging of the mouse brain. Performs behavioral testing using mice. Analyze data using statistical tools. Brain clearing and light-sheet imaging. Imaging using confocal microscopes. Gene cloning, cell culture, proteomics. RNA sequencing, flow cytometry. Performs western blotting, immunohistochemistry and immunocytochemistry. Writing manuscripts.

We are seeking a highly motivated and talented associate scientist to join our team and lead cutting-edge research investigating the therapeutic potential of intrinsically disordered regions. The project will leverage pooled lentiviral screening pipelines of peptide inhibitors to systematically perturb key molecular interactions. This is an exciting opportunity to apply innovative high-throughput screening technologies to reveal new regulatory mechanisms and therapeutic targets. The successful candidates will play a central role in developing and implementing advanced lentiviral-based screening platforms across diverse biological systems, working at the interface of molecular biology, genomics, and translational discovery. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Design, optimize, and execute pooled lentiviral screening workflows for large-scale peptide inhibitor characterization Collaborate closely with bioinformaticians and project investigators to ensure robust experimental design, data acquisition, and analysis. Support the development of innovative experimental strategies to expand and enhance existing screening capabilities. Contribute to collaborative research outputs, including publications and conference presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Demonstrated expertise in the design, production, and application of lentiviral vectors for genetic manipulation and screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Excellent organisational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Extensive expertise in the design, production, and application of lentiviral libraries for large-scale screening. Familiarity with large-scale data generation and interpretation in screening contexts. Proven expertise in the design and execution of assays to characterise protein-protein interactions. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The post-holder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterization of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localisation. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in a relevant scientific area Minimum Experience: 7 + years of research experience is required with a Bachelor's degree. 5 + years of research experience is required with a Master's degree. 2 + years of research experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist (Pooled Lentiviral Base Editing Screening). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Job Description Job Position: Senior Manufacturing Technician or Senior Manufacturing Process Scientist Location: Memphis, TN Duration: Fulltime Permanent Relocation: Relocation Package is Provided Our Client is looking for Senior Manufacturing Process Scientist- With protein purification etc. experience…..!!!!! Position will be responsible for overseeing and executing the process design and manufacturing of monoclonal antibodies, polyclonal antibodies and recombinant proteins products and services sold into IVD industry. The Senior Manufacturing Process Scientist will possess ‘hands-on' experience with various forms of chromatography (affinity, ion exchange, HIC, etc.), centrifugation, TFF/DF/UF, cell culture and fermentation. Experience with aseptic techniques particularly useful in the areas of eukaryotic cell culture, bacterial and yeast fermentation. The individual must be capable of executing and authoring Master Batch Records and Standard Operating Procedures in compliance with current Good Manufacturing Practices. This position will supervise Production Technicians. SUMMARY & RESPONSIBILITIES: • Perform bio separation of recombinant proteins, monoclonal/polyclonal antibodies. Bioseparation methods to include, but not limited to, preparative centrifugation, TFF filtration, and chromatographic methods (ion exchange, size exclusion, affinity, etc.). • Familiar with In vitro cell culture of monoclonal antibodies and fermentation of recombinant proteins. • Develop and perform various analytical protein methods for process monitoring and characterization of in-process and final product. The methods to include but not limited to SDS-PAGE, Western Blot, ELISA, UV-VIS, and Immunoassays methods. • Assess feasibility of contract manufacturing cell culture and purification opportunities, participate in development of proposal and costing estimates. • Author master batch records and SOPs for transferred/developed process in compliance with all current GMP regulations and company SOPs. • Train Production Technicians in upstream and downstream manufacturing processes. • Develop strategies to improving yields and reducing overall manufacturing costs. Investigate alternative materials or new process equipment to improve efficiency. • Write and execute validation protocols for new and existing manufacturing processes. • Assist with the writing of technical reports, customer proposals, and product release specifications Qualifications QUALIFICATIONS AND SKILLS NEEDED: • Ph.D. with 3+ years of industrial experience or MS with 6+ years of industrial experience in a GMP or GLP environment. • Extensive knowledge and hands on experience of protein purification and characterization. • Experience with virus like proteins and viruses a plus. A knowledge of AKTA Unicorn software and disposable systems a plus. • Hands on experience with in vitro cell culture and recombinant protein fermentation • Ability to independently apply bioseparation basic theory and scientific principles to conduct downstream process development for proteins. • Proven experience with process scale-up procedures. • Extensive knowledge and hands on experience with protein analytical methods including (SDS-PAGE, Western Blot, ELISA, BCA, UV-VIS, HPLC methods etc). • Concise and accurate oral and written reporting of technical including batch records, SOPs, validation protocols and customer proposals. • MUST BE US CITIZEN or GREEN CARD holder only. Requirements (Physical, Mental, Environmental Demands): • Ability to walk up and down several flights of stairs throughout the work day in a multi-location facility. • Must be able to concentrate, analyze and solve complex issues throughout the course of the work day. • Ability to work on a PC including repetitive use of a keyboard and mouse for long periods throughout the course of the work day. • Ability to sit for long periods of time, stoop, reach, bend throughout the course of the work day. • Must be able to lift up to 30lbs. multiple times daily. • Must be able to travel by air/car to other locations of MBI as needed. • May be required to work outside normal business hours including evenings and/or weekends to support business needs. Additional Information Regards Pooja Mishra Clinical Recruiter Integrated Resources, Inc. IT Life Sciences Allied Healthcare CRO Certified MBE |GSA - Schedule 66 I GSA - Schedule 621I Tel: 732 429 1636 (W) 732-549-2030 x 214 | (F) 732-549-5549 Gold Seal JCAHO Certified ™ for Health Care Staffing “INC 5000's FASTEST GROWING, PRIVATELY HELD COMPANIES” (8th Year in a Row)

FUNDED UNTIL JANUARY 1, 2027. JOB SUMMARY/ESSENTIAL JOB FUNCTIONS: The Department of Genetics, Genomics, and Informatics at the University of Tennessee Health Science Center is seeking a Postdoctoral Scholar. This position involves rodent handling and in vitro cell-based assays. It requires knowledge of rodent colony management and behavior, preparation of primary cell cultures, knowledge of basic molecular biology techniques, and a background in statistical analysis, and familiarity with statistical packages (e.g., JMP, Prism, R, or Python.) The position involves working independently and supervising graduate students and technical staff. It will require the ability to analyze and summarize results and present research findings in the form of weekly lab meetings, scientific conference posters and presentations, and manuscript preparation. MINIMUM REQUIREMENTS: Doctoral Degree. KNOWLEDGE, SKILLS, AND ABILITIES: Meticulous record-keeping skills. Attention to detail and basic computer skills. Basic knowledge of statistics and statistical software. Excellent communication and presentation skills. Ability to work as part of a team and follow directions. Ability to plan and complete experiments promptly and around the schedule of important collaborators and institutional cores. Performs and/or supervises trainee in vitro cell-based assays in primary neuronal and astrocyte cultures. Specific duties include culturing primary cells, transduction using viral vectors, flow cytometry, and sea horse assays. Assists with nucleic acid extractions, protein extractions, and other basic molecular biology as needed. Performs statistical analysis and quality control of data generated from molecular and behavioral assays. Prepares results for publication and presents data at internal and external meetings. Prepares weekly reports for lab meetings. Performs and/or supervises all aspects of rodent studies, including colony maintenance, estrus cycle monitoring, timed matings, embryo collection, blood collection, tissue collections, perfusions, injections, and performing multiple different behavioral phenotyping assays. May also perform stereotaxic injections to deliver viral vectors to select rodent brain regions.

An Associate Scientist performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Also, performs tasks related to the research project independently, but within broad guidelines and subject to periodic review by supervisor or other research staff. An Associate Scientist position is available for a highly motivated scientist with a background in Circuits or Systems Neuroscience to coordinate the application of in vivo methodologies to assess neural function and animal behavior with multiple labs in the Developmental Neurobiology (DNB) department. This position is well-suited for an individual interested in transitioning from a postdoctoral position to a more stable, long-term position. The successful candidate will work directly with DNB labs to establish standard and innovative approaches for monitoring animal behavior in a wide variety of assays (motor, stress, cognitive, etc). It's expected that qualified candidates would have direct experience with several of the following methodologies: optogenetics, fiber photometry, in vivo calcium imaging, and/or machine-learning-based behavioral assessment. Additionally, it will be important for candidates to have familiarity with basic coding practices to coordinate data collection across multiple platforms (e.g, coordinating calcium imaging or optogenetic delivery with behavioral tracking). Job Responsibilities: Perform behavior-related experiments in collaboration with DNB lab members for the establishment and advancement of current projects. Implement and optimize algorithms for analyzing behavior data. Build or implement existing scripts to temporally align data across multiple modalities. Coordinate efforts with DNB researchers and established vendors (Med Associates, Inscopix, TDT Systems) to troubleshoot and optimize behavior-related data collection. Contribute to publications and presentations of research findings Maintains regular and predictable attendance Work independently and collaboratively with DNB labs. Provide guidance and training to less-experienced team members and may also train others outside the lab in relevant techniques. Perform other duties as assigned to meet the goals and objectives of the department and the institution. Maintain regular and predictable attendance. Preferred Qualifications: PhD in neuroscience, biology, computational neuroscience, or related fields. Demonstrated hands-on experience with neural circuit-based approaches. Strong programming skills (Python preferred). Experience analyzing time-series data, preferably from neuroimaging or behavioral studies. Knowledge of statistical analysis. Excellent communication skills and ability to work in a collaborative environment. Minimum Education and/or Training: Bachelor's degree in a relevant scientific area Minimum Experience: 7+ years of research experience is required 5+ years of research experience is required with a Master's degree 2+ years of research experience is required with a PHD Experience leading and supporting research experiments preferred Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred Experience in guiding and training other laboratory personnel is preferred Proven performance in earlier role/comparable role. Preference will be given to applicants who have a strong background in leveraging in vivo approaches to solve complex problems in behavioral neuroscience. The candidate will also benefit from an outstanding, highly collaborative work environment in which research labs have diverse interests in understanding the underlying mechanisms of neural circuit function related to neuromodulation, motor output, and psychiatric disease. The Department of Developmental Neurobiology houses specialized departmental shared resources, including an integrated support structure for in vivo and ex vivo neuroimaging, behavioral phenotyping, computational neuroscience, genetic engineering, and single-cell genomics. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Associate Scientist - Circuits/Systems/Behavioral Neuroscience. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing. Our client is a public and rapidly growing diagnostics company that is looking to expand their Quality team in Memphis TN. They are willing to assist with relocation. This position will have no direct reports. Overview: This position is responsible for carrying out T-SPOT assays and other processes during validation of procedures, QC of finished product and raw materials, and to support the Quality Manager in the running of the Quality Management System and general administration of documentation for the QMS. This will include the following: Responsibilities: Overall responsibilities: 1. Maintenance of reference material, including cell culture and stock validation 2. QC of raw materials, incoming goods and any product manufactured by Oxford Immunotec 3. QC of manufactured products and assembled kits 4. Validation of procedures, equipment and software 5. Planning and conducting of stability testing procedures 6. Performing other laboratory testing as required 7. Maintaining the equipment databases to ensure all equipment is calibrated, maintained and serviced as required 8. Assisting with the control of Quality Management system documentation 9. Assisting with the preparation of further documentation for the Quality Management system 10. Assisting with the monitoring of compliance with the QMS and with tracking systems associated with CLIA, CAP, State requirements, ISO 13485:2012, ISO 9001:2008 and ISO 17025:2005 and the QSR 11. Assist the Quality Manager to ensure the continuing effectiveness of the QMS 12. Assist during internal and external audits 13. Conduct laboratory spot check audits 14. Assist with the QA review of documentation including non-conformances, CAPAs and complaints 15. Perform miscellaneous duties as necessary and requested by the Quality Manager Specific deliverables for the role are: 1. Contributing towards the maintenance of the quality of the Company's products in fulfillment of the Company goals 2. Control and conduct of product stability testing to support expiry dates and shipping claims 3. Monitoring of product conformity through archive kit testing 4. Assisting with ensuring compliance in the manufacturing process and documentation 5. Ensure that areas of responsibility do not contribute to any major non-conformance during external audits for GMP, ISO 13485:2003, ISO 17025:2005 and ISO 9001:2008 6. Regular communication with QA/QC team members and other functional groups to provide QC and validation support for both Process and Design controls 7. Working to Oxford Immunotec's Company Values at all times. 8. Follows all company safety policies & other safety precautions within work area 9. Regular attendance and timeliness is essential Qualifications QUALIFICATIONS: • Bachelor's degree, or college education and equivalent experience • 5+ years Quality experience, preferably in laboratory or medical device environmen ***Must have cell culture experience*** • Good working knowledge of MS Office • Experienced in working to GLP and Quality Management principles • Strong attention to detail and Quality commitment • High standards of mathematics and writing ability • Conscientious, thrives in high pressure work, and demonstrates strong initiative PHYSICAL DEMANDS: The physical demands described within the Position Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Minimal travel required including international travel. Job requires employee to walk considerable distances in the facility during the course of his or her work. Additional InformationAll your information will be kept confidential according to EEO guidelines.

JOB SUMMARY/ESSENTIAL JOB FUNCTIONS: The Department of Physiology is seeking a Postdoctoral Scholar to perform and conduct research in the area of Vascular Biology/Oxidative stress. EDUCATION: PhD or MD. Proficiency in vascular physiology or a related field is required. EXPERIENCE: Experience in molecular biology, pharmacology and biochemistry fields related to basic and translational cardiac and neurovascular metabolic disorders. Previous research experience in cardiovascular and neurological sciences and animal models of disease is highly desirable WORK SCHEDULE: This position may occasionally be required to work weekends. The project includes studying the effects of oxidative stress on the physiological functions of cerebral vessels. Neonatal pigs are used as a clinically relevant large animal model of cerebral vascular disease and blood-brain barrier disruption caused by epileptic seizures and hypoxia-asphyxia. Placing particular emphasis on endogenous antioxidant cytoprotective mechanisms in the neonatal brain. Combine intravital microscopy of the brain vasculature with cellular-molecular studies in cerebrovascular myocytes, endothelial cells, and astrocytes to identify the mechanisms of neurovascular survival during oxidative stress.

We are seeking a highly motivated and talented scientist to join our team and lead cutting-edge research exploring the therapeutic potential of intrinsically disordered regions. This project will harness pooled lentiviral screening platforms for base/prime editing mutagenesis to systematically perturb key molecular interactions. It offers an exciting opportunity to apply innovative high-throughput technologies to uncover new regulatory mechanisms and identify novel therapeutic targets. The successful candidate will play a central role in developing and implementing advanced lentiviral-based screening pipelines across diverse biological systems, working at the interface of molecular biology, genomics, and translational discovery. The World's Brightest Minds Always Innovate At St. Jude Children's Research Hospital, we know what can be achieved when the brightest scientific minds face the fewest barriers. That's why we provide world-class facilities. State-of-the-art technologies. Extraordinary support. And a collaborative, bench-to-bedside environment where you can see, firsthand, how your science translates into survival for the children we serve. Quite simply, at St. Jude, we encourage you to dream big and stop at nothing when it comes to finding cures and saving children. Key Responsibilities: Design, optimize, and execute pooled lentiviral screening workflows for large-scale base/prime editing mutagenesis. Collaborate closely with bioinformaticians and project investigators to ensure robust experimental design, data acquisition, and analysis. Drive the development of innovative experimental strategies to expand and enhance existing screening capabilities. Contribute to collaborative research outputs, including publications and conference presentations. Ideal Candidate: PhD (or equivalent experience) in Molecular Biology, Cell Biology, Genetics, or a closely related field. Demonstrated expertise in the design, production, and application of lentiviral vectors for genetic manipulation and screening. Proven track record in developing, implementing, or applying high-throughput genetic perturbation or functional screening approaches. Excellent organisational, communication, and record-keeping skills. Strong problem-solving ability and capacity to work independently as well as collaboratively. Desirable Attributes: Extensive experience in CRISPR-based genome engineering in mammalian cell systems. Demonstrated expertise in the design, production, and application of lentiviral libraries for large-scale screening. Experience with base or prime editing systems. Familiarity with large-scale data generation and interpretation in screening contexts. Evidence of contributions to collaborative research initiatives or consortia. About the Research Environment: The Davey lab has recently joined the Department of Cell and Molecular Biology to launch a research program applying high-throughput screening approaches to uncover the therapeutic potential of intrinsically disordered regions. The post-holder will work within a collaborative, supportive team and benefit from world-class core facilities and excellent opportunities for professional development. What problem are we tackling? Target discovery is a critical foundation of drug development, underpinning efforts to overcome the persistent challenges of drug resistance, emerging pathogens, and complex diseases that lack effective therapies. By uncovering novel proteins and molecular pathways driving disease progression, we can enable the rational design of more selective interventions that reduce off-target effects and improve patient outcomes. The development of tool molecules, coupled with detailed characterisation of their inhibitory mechanisms, provides a direct bridge between phenotypic observations and small-molecule drug design, accelerating the translation of basic discoveries into clinically actionable therapies. What is our approach? Short Linear Motifs (SLiMs) are compact functional modules embedded within the intrinsically disordered regions of proteins. They mediate a wide range of regulatory processes, including the assembly of dynamic complexes, recruitment of modifying enzymes, control of protein stability, and specification of subcellular localisation. Despite their central role in cellular regulation, SLiM-binding pockets remain a largely untapped class of therapeutic targets. By applying large scale base-editing and peptide inhibitor studies the project will address three key questions: (i) How essential are SLiM-mediated interactions for cellular fitness? (ii) Does SLiM essentiality differ between healthy and diseased cells? (iii) Can these interactions be selectively targeted for therapeutic intervention? Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required with a Bachelor's degree. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Better at Work. Better at Life. When you work at St. Jude, you'll join a highly collaborative work culture that inspires you every day to be your best. With opportunities for learning and growth, you can shape a career path that is right for you while also enjoying all the benefits and stability of working for a world-class institution. This includes work-life balance with generous paid time-off and on-campus conveniences that make life a little easier. Join us and you'll quickly see why St. Jude is consistently ranked by our employees on Glassdoor as a “Best Place to Work.” Benefits Your health and well-being are important to us. That's why St. Jude Children's Research Hospital provides employees with high-quality benefits choices. We are committed to ensuring our benefits are competitive and affordable. St. Jude continues to cover medical premiums for employees and offers low additional costs for dependents. View all the benefits offered including Medical & Prescription Drug Plans, Dental Plan, Vision Plan, Financial Security, Retirement Plan, Living Well - Employee Wellness Program, Time Off Programs, Educational Benefits, Family Friendly Benefits, and Benefits Unique to St. Jude. Have More in Memphis Get the best of big-city amenities mixed with all the charm of a small-town feel when you live in Memphis. From our world-renowned music scene to our eclectic mix of food and people. Memphis is a place our employees are proud to call home. Our region enjoys a cost of living more than 20% lower than the national average and our state places no personal income tax on wages. Plus, Memphians spend five hours less per year in their daily commute compared to the national average. Learn how you can “Have More in Memphis.” Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Scientist (Pooled Lentiviral Base Editing Screening). Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The University of Tennessee Health Science Center is the flagship statewide, public, academic health institution in Tennessee. Founded in 1911, the mission of the University of Tennessee Health Science is to improve the health and well-being of Tennesseans and the global community by fostering integrated, collaborative, and inclusive education, research, scientific discovery, clinical care, and public service. Employing more than 4,600 people on its faculty, staff, and not-for-profit corporation faculty practice groups, and with more than 3,200 students across the state, UTHSC contributes $4 billion to the economy of Tennessee. Part of the University of Tennessee System, the Health Science Center is headquartered in Memphis and includes all six of UT's doctoral-degree-granting health science colleges -- Medicine, Dentistry, Pharmacy, Nursing, Graduate Health Sciences, and Health Professions. UTHSC spans the state with its four major, regional clinical health science locations in Memphis, Knoxville, Chattanooga, and Nashville, as well as more than 100 clinical education sites across Tennessee. UTHSC is the largest educator of health care professionals in the state and operates the state's largest residency and fellowship advanced training programs. Located in West Tennessee on the banks of the Mississippi River, Memphis is the second-largest city in the state and among the largest cities in the Southeast. The Greater Memphis metropolitan area has more than 1.3 million residents, and the city ranks among those with the lowest cost of living in the country. It is home to a vibrant restaurant scene, a revitalized Downtown, the Midtown Arts District, many scenic neighborhoods, an active medical district, and a burgeoning airport in the midst of a $214 million modernization. Memphis boasts attractions, including Elvis Presley's Graceland, the Memphis Grizzlies, historic Beale Street, the National Civil Rights Museum, the second-largest urban county park in the United States, and the Memphis in May World Championship Barbecue Cooking Contest. Responsibilities Applicants should have a demonstrated commitment to and knowledge of equal employment opportunity and affirmative action. Qualifications PhD in Biological or Biomedical Sciences, or a closely related field. Minimum four-years' experience in research that may include PhD thesis, at least three publications as the first or the senior author, familiarity with biochemical, molecular, cell biological assays, data management and data analysis, research with laboratory animals specifically mouse and rats, and strong communication and excellent writing skills.

Join Our Team! The Center of Excellence for Pediatric Immuno-Oncology (CEPIO) is seeking an experienced Scientist to manage the Center's immuno-oncology preclinical murine modeling core. CEPIO serves as the central hub to advance and coordinate cross-disciplinary studies in immuno-oncology across St. Jude basic and clinical Departments, Cores, and Centers. The successful candidate is expected to have significant prior experience in developing and standardizing preclinical murine models to support target discovery, validation, and functional testing, including the generation of new genetically engineered mouse models (GEMMs). The Scientist will play a central role in developing and managing faithful disease models in vivo (e.g., GEMMs, surgically induced murine models) to support immuno-oncology research and translational efforts. This position offers the opportunity to engage in high-impact research with translational potential, contributing directly to developing novel cancer immunotherapies. Maintaining an up-to-date knowledge of, and having a high level of enthusiasm for, new and emerging technologies in preclinical murine modelling for immuno-oncology and their potential applications will be important. This includes beta-testing new tools, customizing technologies to fit CEPIO's research needs, and developing in-house protocols for complex experiments. The ideal candidate will work with collaborators across CEPIO with the goals of establishing faithful models to enable and support immuno-oncology research and translational efforts. Responsibilities Coordinate multiple aspects of research projects and execute laboratory experiments utilizing appropriate laboratory techniques, tools, and methods. Provide inputs regarding research protocols and experiments, set up protocols, and assist in developing new laboratory techniques as required. Identify, process, organize, summarize, review, and report relevant experimental data. Draft sections of research manuscripts as directed. Support monitoring and stocking of supplies, and calibration, maintenance, troubleshooting, and purchase of equipment within area. Instruct other staff in basic laboratory techniques and procedures. Design, troubleshoot, and refine experimental approaches to answer critical research questions. Process, organize, and analyze complex datasets, providing detailed reports on findings. Provide technical support for ongoing projects, including maintaining datasets, lab documentation, and compliance with safety regulations. Engage in collaborative research projects with internal and external teams to advance research and translation in immuno-oncology. Maintain regular and predictable attendance, contributing to a positive and productive lab environment. Minimum Education and/or Training: Bachelor's degree in relevant scientific area is required. Minimum Experience: Eight (8) years of relevant work experience is required. Six (6) years of relevant work experience is required with a Master's degree. Three (3) years of relevant work experience is required with a PhD. Prior experience in lab techniques is preferred. Experience in lab and scientific project coordination, maintenance, and other research support activities preferred. Prior experience with the generation of GEMMs in immunology and/or cancer biology is highly preferred. Professional Growth Opportunities CEPIO provides a vibrant research environment with access to advanced tools and resources, including state-of-the-art imaging platforms and cutting-edge molecular biology techniques. CEPIO fosters a culture of collaboration, offering opportunities for professional development and advancement. We invite motivated scientists passionate about preclinical murine models and immuno-oncology to apply and join us in pushing the boundaries of immuno-oncology and immunotherapy in the fight against pediatric cancers. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Preclinical Modeling Scientist - Center of Excellence for Pediatric Immuno-Oncology. Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The Postdoctoral Scholar performs and conducts research in cardiovascular and neuronal research in the Department of Physiology. Responsibilities Performs critical experiments studying the disruption of calcium homeostasis in the setting of cardiac and neuronal damage. Studies underlying molecular signaling. Utilizes approaches including the extensive use of mouse models, molecular biology and biochemistry, immunofluorescence, super-resolution microscopy, calcium imaging, and surgical procedures. Performs other duties as assigned. Qualifications PhD or MD in Physiology or a related field of study. Experience in Molecular Biology, Pharmacology, and Biochemistry fields related to basic and translational cardiac and neurovascular metabolic disorders. Previous research experience in cardiovascular and neurological sciences and animal models of disease is highly desirable.